NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2088662739|gb|QZR91982|]
View 

NADH dehydrogenase subunit 2 (mitochondrion) [Filchnerella sunanensis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 2.55e-97

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 291.34  E-value: 2.55e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIQL 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  81 KYPLNWEqqiIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIqNSMFISTIIIMSIAI 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI-NNNFIIIIIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 161 GALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 241 FLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNMKSPKFILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*...
gi 2088662739 321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160  317 FLSFISLFGLILSSLLFL 334
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 2.55e-97

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 291.34  E-value: 2.55e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIQL 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  81 KYPLNWEqqiIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIqNSMFISTIIIMSIAI 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI-NNNFIIIIIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 161 GALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 241 FLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNMKSPKFILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*...
gi 2088662739 321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160  317 FLSFISLFGLILSSLLFL 334
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 2.83e-27

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 108.55  E-value: 2.83e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  24 SNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNEPSIKYFIVQAMASTMLLFSILII--------------QLKYPLNWEQ 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  89 QIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMML-MTWQKIAPMMVL-------SYCIQNSMFISTIIIMSIAI 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 161 GALGGLNQISLRQLMAYSSISHLGWMIASISI----SETMWEVYFLVYSLLSVIMILLFN-----QSKLFFMNQIYTSEN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAGsviyrRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2088662739 232 MNIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-293 1.75e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 1.75e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   8 LLFLSSLmmGTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNEPSIKYFIVQAMASTMLLF----------SIL 76
Cdd:COG1007   107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  77 IIQLKYPLNWEQQIIPSMMISSSLLL-----KIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVL---------SY 142
Cdd:COG1007   185 LAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpGL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 143 CIQNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWM-IASISISETMWE---VYFLVYSLLSV---IMILLF 215
Cdd:COG1007   265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLGVSaalFYLLAYLFMNLgafAVILLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 216 NQSKlffmnqiytSENMNIE-----------IKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTI 284
Cdd:COG1007   345 SRKG---------GEAEEIEdlaglarrsplLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVI 415


                  ....*....
gi 2088662739 285 TLYYYMRIM 293
Cdd:COG1007   416 SAYYYLRVV 424
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-331 7.88e-22

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 95.79  E-value: 7.88e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  17 GTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNEPSIKYFIVQAMASTMLLFSILII----------QLKYPLN 85
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslnfeDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  86 WEQQIIPSM-----MISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIA---PMMVLSYCIQ------NSMFIS 151
Cdd:TIGR01770 194 NGMLNISLLllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgfseaWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 152 TIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWE----VYFLVYSLLSV----IMILLFNQSK---- 219
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkavlFYIFIYALMSLgafgVLSLLRSYKDewie 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 220 -LFFMNQIYTSenmNIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRImfsAMI 298
Cdd:TIGR01770 354 yISDFAGLFKT---NPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKV 427

                         330       340       350
                  ....*....|....*....|....*....|....
gi 2088662739 299 MTFSE-NSWSINNNMKSPKFILPTLVTISTLGLI 331
Cdd:TIGR01770 428 MYFDKpERRIPSNPQSKAQSLLLSISALFILFLG 461
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 2.55e-97

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 291.34  E-value: 2.55e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIQL 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  81 KYPLNWEqqiIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIqNSMFISTIIIMSIAI 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI-NNNFIIIIIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 161 GALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 241 FLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNMKSPKFILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*...
gi 2088662739 321 TLVTISTLGLISTSTMIS 338
Cdd:MTH00160  317 FLSFISLFGLILSSLLFL 334
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 8-340 2.28e-66

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 212.40  E-value: 2.28e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   8 LLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSIlIIQLKYPLNWE 87
Cdd:MTH00105    7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAI-IINLMYSGQWT 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  88 QQIIP----SMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLsYCIQNSMFISTII---IMSIAI 160
Cdd:MTH00105   86 ITKLTnptaSTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSIL-YQISPSINPNLLLtlaILSILI 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 161 GALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLM 240
Cdd:MTH00105  165 GGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLI 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 241 FLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSEnswsiNNNMK------- 313
Cdd:MTH00105  245 LLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPS-----TNNMKmkwqfen 319

                         330       340
                  ....*....|....*....|....*...
gi 2088662739 314 -SPKFILPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00105  320 tKPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 6-340 1.19e-64

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 208.14  E-value: 1.19e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   6 TKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSIL--------- 76
Cdd:MTH00112    5 AKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTtnawntgqw 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  77 -IIQLKYPlnweqqiIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLsYCIQNSM---FIST 152
Cdd:MTH00112   85 dITQLTNP-------TSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLL-LMTSNSLnptLLLT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 153 IIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENM 232
Cdd:MTH00112  157 LAILSTLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTK 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 233 NIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMI-----MTFSENSWS 307
Cdd:MTH00112  237 SPTLNTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTItlppnTTNMMMKWR 316

                         330       340       350
                  ....*....|....*....|....*....|...
gi 2088662739 308 INNNMKSPkfiLPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00112  317 TKPKKNTL---TATLTTLSTLLLPLSPMILTII 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 8-340 8.42e-63

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 203.24  E-value: 8.42e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   8 LLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSILiIQLKYPLNW- 86
Cdd:MTH00041    7 IFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGAL-IQAWLSGSWs 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  87 ---EQQIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQ--NSMFISTIIIMSIAIG 161
Cdd:MTH00041   86 ingPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNllNSNILILCGILSVLVG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 162 ALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLMF 241
Cdd:MTH00041  166 GWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFI 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 242 LTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNMKSPKF---- 317
Cdd:MTH00041  246 LSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNItvyg 325

                         330       340
                  ....*....|....*....|....
gi 2088662739 318 -ILPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00041  326 vILSILSSISILGLLLIPLFLSFL 349
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 9-339 2.13e-60

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 196.95  E-value: 2.13e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   9 LFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSIL----------II 78
Cdd:MTH00135    8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnawltgqwdIQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  79 QLKYPLnweqqiiPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMmVLSYCIQ--NSMFISTIIIM 156
Cdd:MTH00135   88 QMSHPL-------PTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPF-ALILQIAptNPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 157 SIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEI 236
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 237 KFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFsAMIMTFSENswsiNNNMKSPK 316
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSY-AMTLTISPN----TLNGTTPW 314

                         330       340
                  ....*....|....*....|...
gi 2088662739 317 FILPTLVTIstlgLISTSTMIST 339
Cdd:MTH00135  315 RLPSTQLTL----PLAISTTATL 333
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 10-340 3.75e-60

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 196.30  E-value: 3.75e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  10 FLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSILI---IQLKYPLNW 86
Cdd:MTH00070    9 LLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTInawFTGEWTIMN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  87 EQQIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQ--NSMFISTIIIMSIAIGALG 164
Cdd:MTH00070   89 MQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHllNSNLLIIMGLLSTLIGGWG 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 165 GLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLMFLTL 244
Cdd:MTH00070  169 GLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTL 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 245 LSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFsAMIMTFSENS------WSINNNmksPKFI 318
Cdd:MTH00070  249 LSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSY-AMSLTTSPNTsnsklyWRFKNK---TNNL 324

                         330       340
                  ....*....|....*....|..
gi 2088662739 319 LPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00070  325 LSLTIILSLMLLPITPTILNLF 346
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 3-320 2.09e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 180.85  E-value: 2.09e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   3 SNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIqlkY 82
Cdd:MTH00144    2 SSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIM---Y 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  83 PLNWEQQIipSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNSMFISTIIIMSIA--- 159
Cdd:MTH00144   79 NLSFSWFS--MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVLsal 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 160 IGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIyTSENMNIEIKFL 239
Cdd:MTH00144  157 VGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDL-GSLKPSYKTGLS 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 240 MFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNMKSPKFIL 319
Cdd:MTH00144  236 IISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSIISL 315


                  .
gi 2088662739 320 P 320
Cdd:MTH00144  316 N 316
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 6-340 6.64e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 180.16  E-value: 6.64e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   6 TKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSIL---IIQLKY 82
Cdd:MTH00200    5 ILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLlnaWTSGQW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  83 PLNWEQQIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLS--YCIQNSMFISTIIIMSIAI 160
Cdd:MTH00200   85 GISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 161 GALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLM 240
Cdd:MTH00200  165 GGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 241 FLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMT--FSENSWSINNNMKSPKFI 318
Cdd:MTH00200  245 GLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLspNQINMMSSWRTKSNSNLL 324

                         330       340
                  ....*....|....*....|..
gi 2088662739 319 LPTLVTISTLGLISTSTMISTF 340
Cdd:MTH00200  325 VGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-337 3.68e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 177.56  E-value: 3.68e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   9 LFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIQLKYPLnweq 88
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYL---- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  89 QIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNSMFISTIIIMSIAIGALGGLNQ 168
Cdd:MTH00197   78 SLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 169 ISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKFLMFLTLLSLG 248
Cdd:MTH00197  158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 249 GLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTfseNSWSINNNMKSPKFILPTLVTISTL 328
Cdd:MTH00197  238 GLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILS---NWMINFLMKINLLYSGLFILLMMML 314


                  ....*....
gi 2088662739 329 GLISTSTMI 337
Cdd:MTH00197  315 PLLMIFTMI 323
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-331 2.91e-49

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 167.65  E-value: 2.91e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   1 MTSNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSIliiQL 80
Cdd:MTH00011    2 MSTFPTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM---TM 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  81 KYPLNWEQQIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYC--IQNSMFISTIIIMSI 158
Cdd:MTH00011   79 MWSFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFtsHNILPMMTSMAAMSA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 159 AIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSENMNIEIKF 238
Cdd:MTH00011  159 LAGGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSM 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 239 LMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMtfSENSWSINNNMKSPKFI 318
Cdd:MTH00011  239 SLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYL--SPTFSSLKSAPYEPKTK 316

                         330
                  ....*....|...
gi 2088662739 319 LPTLVTISTLGLI 331
Cdd:MTH00011  317 ILISMCTLSLGLI 329
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 2.83e-27

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 108.55  E-value: 2.83e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  24 SNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNEPSIKYFIVQAMASTMLLFSILII--------------QLKYPLNWEQ 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMynytgtlsfdelskALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  89 QIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMML-MTWQKIAPMMVL-------SYCIQNSMFISTIIIMSIAI 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 161 GALGGLNQISLRQLMAYSSISHLGWMIASISI----SETMWEVYFLVYSLLSVIMILLFN-----QSKLFFMNQIYTSEN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAgtiyGIQAAIFHLLTHGLFSAGLFLCAGsviyrRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2088662739 232 MNIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-319 1.83e-25

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 105.11  E-value: 1.83e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  16 MGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMN-EPSIKYFIVQAMASTMLLF----------SILIIQLKYPL 84
Cdd:MTH00196    4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGYSaEAGLKYFVLGALSSGLFLFgcallcgttgGLHLSYINLVL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  85 NWEQQI------IPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNSMFISTIIIMSI 158
Cdd:MTH00196   84 NSGQSFssvsvpIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 159 AIGALGGLNQISLRQLMAYSSISHLGWMIASISI-------SETMWEVYFLVYSLLSVIMILLFNQSKLFFMNQIYTSEN 231
Cdd:MTH00196  164 FVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfesiqASLVYLFIYIIMSICVFSIILALNVYKNLIIEFSGLSRR 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 232 MNIeIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMfsaMIMTFSENSW--SIN 309
Cdd:MTH00196  244 LPI-LAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV---KILFFQANSFllIST 319

                         330
                  ....*....|
gi 2088662739 310 NNMKSPKFIL 319
Cdd:MTH00196  320 KILKKENKIN 329
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-293 1.75e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 1.75e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   8 LLFLSSLmmGTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNEPSIKYFIVQAMASTMLLF----------SIL 76
Cdd:COG1007   107 LLLFATL--GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygatgSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  77 IIQLKYPLNWEQQIIPSMMISSSLLL-----KIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVL---------SY 142
Cdd:COG1007   185 LAGIAAALAAGGANSPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveafpGL 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 143 CIQNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWM-IASISISETMWE---VYFLVYSLLSV---IMILLF 215
Cdd:COG1007   265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPLGVSaalFYLLAYLFMNLgafAVILLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 216 NQSKlffmnqiytSENMNIE-----------IKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTI 284
Cdd:COG1007   345 SRKG---------GEAEEIEdlaglarrsplLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVI 415


                  ....*....
gi 2088662739 285 TLYYYMRIM 293
Cdd:COG1007   416 SAYYYLRVV 424
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-303 5.67e-24

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 101.82  E-value: 5.67e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   8 LLFLSSLMmGTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNEPSIKYFIVQAMASTMLLF----------SIL 76
Cdd:PRK05777  107 LLVLFALL-GMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYgmsllygatgSLS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  77 IIQLKYPLNWEQQIIPSM-----MISSSLLLKIGAAPFHFWFPEV-----------MGATSWINCMMLMTwqKIAPMMVL 140
Cdd:PRK05777  186 FAGIAKALADGSGNSLLLlfglvFLLVGLAFKLSAVPFHMWTPDVyegaptpvtafLATAPKIAAFAVLL--RLLVVAFG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 141 SYCIQNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIM------ILL 214
Cdd:PRK05777  264 GLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFMtlgafgVIS 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 215 FNQSKLFFMNQIYTSENMNIE---IKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMR 291
Cdd:PRK05777  344 LLRRKGGEAESISDFAGLSKRsplLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLR 423

                         330
                  ....*....|..
gi 2088662739 292 IMfsaMIMTFSE 303
Cdd:PRK05777  424 VI---KLMYFDE 432
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-292 5.35e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 96.24  E-value: 5.35e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  16 MGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMN-EPSIKYFIVQAMASTMLLFSILiiqLKYPLNWEQQI---- 90
Cdd:MTH00199  108 LGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSAYStEAGLKYFVLGAVSSGLFLFGCA---LLYGLTGETSIqgin 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  91 ------IPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIApmmVLSYCIQNSMFISTII---IMSIAIG 161
Cdd:MTH00199  185 siltgdVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIG---VFSILVQIGPVTNVVLicaVLSIIYG 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 162 ALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIM------ILLFNQSKLFFMNQIYTSENMNIE 235
Cdd:MTH00199  262 AIGALNQTKIKRLLAYSGIGHMGFILFGVAIGSFESIQASLIYMIIYVIMsicsfsIILSLKLTKGLIVEVSGLSRKNPV 341

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2088662739 236 IKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRI 292
Cdd:MTH00199  342 IALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 17-331 7.88e-22

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 95.79  E-value: 7.88e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  17 GTVLSVSSNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNEPSIKYFIVQAMASTMLLFSILII----------QLKYPLN 85
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslnfeDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  86 WEQQIIPSM-----MISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIA---PMMVLSYCIQ------NSMFIS 151
Cdd:TIGR01770 194 NGMLNISLLllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILfgfseaWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 152 TIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWE----VYFLVYSLLSV----IMILLFNQSK---- 219
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIkavlFYIFIYALMSLgafgVLSLLRSYKDewie 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 220 -LFFMNQIYTSenmNIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRImfsAMI 298
Cdd:TIGR01770 354 yISDFAGLFKT---NPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKV 427

                         330       340       350
                  ....*....|....*....|....*....|....
gi 2088662739 299 MTFSE-NSWSINNNMKSPKFILPTLVTISTLGLI 331
Cdd:TIGR01770 428 MYFDKpERRIPSNPQSKAQSLLLSISALFILFLG 461
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-293 4.26e-17

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 82.21  E-value: 4.26e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  16 MGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPS---------IKYFIVQAMASTMLLF------------- 73
Cdd:MTH00198  199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHFPSpgntppesgLKYWILGAMSSGFYLFgcalyfgftgneg 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  74 ---SILIIQLKYP-LNWEQQIIPSMMISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNSMF 149
Cdd:MTH00198  279 mlgTILSATLETTnIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKL 358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 150 ISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISI-------SETMWEVYFLVYSLLSVIMILLFN------ 216
Cdd:MTH00198  359 LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAgtyeslqASWTYAVTYLVSALASFTVICTLEefgtrt 438

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 217 ------QSKLFFMNQIYTSENMNI------EIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAI------- 277
Cdd:MTH00198  439 ptsrqrDGSFGNYNLVRRLVDLTIlsrgqpYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKIAFSSSLSIyylvalf 518

                         330
                  ....*....|....*.
gi 2088662739 278 MTVLTTITLYYYMRIM 293
Cdd:MTH00198  519 AIICTCISAFYYIRIV 534
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-296 7.59e-17

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 80.96  E-value: 7.59e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  10 FLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSILIIQLKYP-LNWEQ 88
Cdd:COG0651   112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGtLNMAD 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  89 ------------QIIPSMMISSSLLLKIGAAPFHFWFPEVMG-ATSWINCMM--LMTwqKIAP-----MMVLSYCIQNSM 148
Cdd:COG0651   192 laarlaeldpglLLAAFALLLVGFGIKAALFPLHFWLPDAYPaAPSPVSALLsgLLT--KVGVyailrVLTLLFGADPAL 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 149 FISTIII----MSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISIsetmwevyFLVYSLLSVIMILL---FNQSKLF 221
Cdd:COG0651   270 FLGTLLLvlglLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGL--------GTPLGLAGALFHLLnhaLAKALLF 341

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 222 F----MNQIYTSENMNIE---------IKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYY 288
Cdd:COG0651   342 LaagaIERATGTRDLDKLgglgkrmplTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAY 421


                  ....*...
gi 2088662739 289 YMRIMFSA 296
Cdd:COG0651   422 FVRIFGRA 429
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 6-296 7.33e-10

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 60.11  E-value: 7.33e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   6 TKLLFLSSLMMGTVLSvssNSWFGVWMGLEINLLSFIPLLA-NNKNMMMNEPSIKYFIVQAMASTMLLFSILIIQLKY-P 83
Cdd:PRK08376  125 TLILLLELGMLGMAIT---GDLFNFFVFLEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGIALLYGQYgT 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  84 LN------------WEQQIIPSMMISSSLLLKIGAAPFHFWFPEVMG-ATSWINCMMLMTWQ-KIAPMMVLSYCIQ---- 145
Cdd:PRK08376  202 LNmaylavkmsenpTVVAKIALALFIAGLAMKSGAVPVHMWLPDAYPaAPSSISAMLLVIKQaGLYALARVLFSIYgpai 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 146 NSMFISTIII----MSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISI------SETMWEV--------------YF 201
Cdd:PRK08376  282 NLATVGWVIIilgcLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLGLGVglaalgDPAMASYgeialaggiyhivnHA 361

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 202 LVYSLLSVIMILLFNQSKLFFMNQIY-TSENMNIEIKFLMfLTLLSLGGLPPFLGFMPKWMVMQSMVENNlSALMAIMTV 280
Cdd:PRK08376  362 LYKALLFLTAGAVIYETGTRNLNELGgLARTMPKTTIAFL-IGAAAIVGLPPFNGFASKWLIYESSALFN-PILGVIAMI 439

                         330
                  ....*....|....*.
gi 2088662739 281 LTTITLYYYMRIMFSA 296
Cdd:PRK08376  440 GSVLTLASFVKVFHTA 455
PRK12650 PRK12650
DUF4040 family protein;
94-298 1.93e-08

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 55.82  E-value: 1.93e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  94 MMISSSLLLKIGAAPFHFWFPEVMGATSWINCMM---LMTWQKIAPMMVLSYCIQNSMFISTIII---MSIAI-GALGGL 166
Cdd:PRK12650  212 VLIAVAAFTKSAQFPFHFWLPEAMAAITPVSAFLhaaAVVKAGIYLLLRFSPVFHDVAVWNWLLIivgMITALmGAVFAV 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 167 NQISLRQLMAYSSISHLGWMIASISISETmwevYFLVYSLLSVIMILLFnQSKLFFMNQIYTSENMNIEIKFL------- 239
Cdd:PRK12650  292 QKTDLKKLTAYSTVSQLGWIVATIGVGTP----FALTAAVVHTLAHALF-KSSLFMLIGVVDHQAGTRDIRRLgslwrrm 366

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 240 ------MFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSA-----LMAIMTVLTTITLYYYMRIMFSAMI 298
Cdd:PRK12650  367 pftfvsVTIAALSMAAVPPLFGFVSKEGMLTAFLEAPGGNagvvlLLVGAALGAVFTFAYSARLVLGAFV 436
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-295 3.52e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 54.59  E-value: 3.52e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  55 EPSIKYFIVQAMASTMLLFSILIIQLKY---------PLNWEQQIIPSMMISSSLLLKIGAA---------------PFH 110
Cdd:PRK12667  164 EAAIKYALIGAVGTTLYFLALAFLYATFgtlnmadlsAKIRGLSFPLTGGLAGNPPLALGVAlalalwaftikaaifPNH 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 111 FWFPEVM-GATSWINCMMLMTWQK-----IAPMMVLSYCIQNS------MFISTIIIM---SIAIGALGGLNQISLRQLM 175
Cdd:PRK12667  244 FWLPDAHpAAPSPVSAMLSGLVVNvgayaIIRFLYTIFGISPSlidfraALSPILIILgavSAIIGALMMVVQKDVKRLL 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 176 AYSSISHLGWMIASISISETMWEVYFLVYSLL-SVIMILLFNQSKLFF-------MNQIYTSENMNIEIKFLMFLTLLSL 247
Cdd:PRK12667  324 AYSTISHMGYIFMGIGIGTQLGLAAALFHIINhAIAKSLLFLASGVFIhaagtrdIDELAGLGRKMPIASFAFLIGALSL 403

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2088662739 248 GGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFS 295
Cdd:PRK12667  404 VGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
147-296 8.13e-08

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 53.42  E-value: 8.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 147 SMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISI---SETMWEVYFLVYS--------LLSVIMILLF 215
Cdd:PRK12663  272 HPLLATMAAITMVIGALGALAYKDIRRIAGYQVISSIGFILLGLALgtpAGINGAIFYLVHDmvvktalfLIAGSLVRLT 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 216 NQSKLFFMNQIYTSENMnieIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFS 295
Cdd:PRK12663  352 GYRSLQYLGGLYRKEPL---FGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRIFFL 428


                  .
gi 2088662739 296 A 296
Cdd:PRK12663  429 A 429
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
54-292 1.88e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 52.36  E-value: 1.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  54 NEPSIKYFIVQAMASTMLLFSIliiQLKYPLNWEQ----QIIPSMMISSSLLL-------------KIGAAPFHFWFPEV 116
Cdd:PRK02504  160 NEAALKYLLIGAASSAIFLYGS---SLLYGLSGGStqlsAIALALITSPSLGLalalvfviagiafKISAVPFHQWTPDV 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 117 MGATSWINCMMLMTWQKIA----PMMVLSYCI-----QNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGW-M 186
Cdd:PRK02504  237 YEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFpsfdeQWKLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFvM 316

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 187 IASISISETMWE---VYFLVY---SLLSVIMILLFnqSKLFFMNQIYTSENMNIEIKFLMF---LTLLSLGGLPPFLGFM 257
Cdd:PRK02504  317 IGLVAGTEAGYAsmvFYLLAYlfmNLGAFACVILF--SLRTGTDQISDYAGLYQKDPLLTLglsLCLLSLGGIPPLAGFF 394

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2088662739 258 PKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRI 292
Cdd:PRK02504  395 GKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRV 429
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 34-292 3.39e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 51.80  E-value: 3.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  34 LEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFSI-LIIQLKYPLNWE--QQIIPSM--------MISSSLLL 102
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVgLLYGVTGTLNMAdlAGALAENptvvtafgFVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 103 KIGAAPFHFWFPEVMGATS--------------WINCMMLMTWQ--KIAPMMVLSYCIqnsmFISTIIIMSIAIGALGGL 166
Cdd:PRK08375  215 KAAVFPLHTWLPRAYPAAPpvvtallsglvtkvAVYALIRIYFTvfGGDFRFALGLGW----LLAVLALLSMLVGSLAAL 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 167 NQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMIllfnqSKLFF----MNQIYTSENMN--------I 234
Cdd:PRK08375  291 GQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLHHALMK-----GALFLaagaIEVTYGTRRLSelsglgrrM 365

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2088662739 235 EIKFLMFLTL-LSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRI 292
Cdd:PRK08375  366 PLTAAAFAVAsLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRI 424
ndhB CHL00049
NADH dehydrogenase subunit 2
 49-315 9.95e-07

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 50.00  E-value: 9.95e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  49 KNMMMNEPSIKYFIVQAMASTMLL--FSILI------IQLKYPLN--WEQQIIPSMMISSSLLL-------KIGAAPFHF 111
Cdd:CHL00049  156 KDVRSNEATMKYLLMGGASSSILVygFSWLYglsggeIELQEIVNglINTQMYNSPGISIALIFitvgigfKLSLAPFHQ 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 112 WFPEVMGATSWINCMMLMTWQKIAPMM--------VLSYCIQNSMFISTII-IMSIAIGALGGLNQISLRQLMAYSSISH 182
Cdd:CHL00049  236 WTPDVYEGSPTPVVAFLSVTSKVAASAlatrifdiPFYFSSNEWHLLLEILaILSMILGNLIAITQTSMKRMLAYSSIGQ 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 183 LGW-MIASISISETMWEVYFLVYSLLSVIMIL-LFNQSKLFFM----NQIYTSENMNIEIKFLMF---LTLLSLGGLPPF 253
Cdd:CHL00049  316 IGYvIIGIIVGDSNDGYASMITYMLFYIFMNLgTFACIVLFGLrtgtDNIRDYAGLYTKDPFLALslaLCLLSLGGIPPL 395

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2088662739 254 LGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNMKSP 315
Cdd:CHL00049  396 AGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKIIKLLMTGRNQEITPYVRNYRRSP 457
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 14-312 4.29e-05

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 44.48  E-value: 4.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  14 LMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNepsikYFIVQAMASTMLLFSILIIQLkyplnweqqiips 93
Cdd:MTH00091    3 LSLLNFMSLNIFVWWSVFLLMTLLFVFLNKGMGSYSSLFNY-----FVLQESLGLLFLLFSFGYFQF------------- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  94 mmisSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNSMFIstIIIMSIAIGALGGLNQISLRQ 173
Cdd:MTH00091   65 ----LILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFF--LLLFGLLICFFQMFLLKSYKN 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 174 LMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMILLFnqsklffmnqiytseNMNIEIKFLMFLTLLSLGGLPPF 253
Cdd:MTH00091  139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKF---------------NNVNKLNFVSWETLLVFMNLPFS 203

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2088662739 254 LGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIMFSAMIMTFSENSWSINNNM 312
Cdd:MTH00091  204 VTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFFF 262
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 3-305 8.47e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 44.04  E-value: 8.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739   3 SNSTKLLFLSSLMMGTVLSVSSNSWFGVWMGLEINLLSFIPLLANNKNMMMNEPSIKYFIVQAMASTMLLFS--ILIIQL 80
Cdd:PRK06589  114 SSSRFLFFFNLTILIGVLIALSSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPavILIYTK 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  81 KYPLNWEQQII----PSMMISSSLLLKIGAA---PFHFWFPEVMGATSWINCMM---------LMTWQKIAPMM----VL 140
Cdd:PRK06589  194 TGNLDFVSGGLfsknQSIILLLMFIYGIAKTaifPVHSWLPAAMVAHYPVSALLhavivvktgLFCIYKILLYIfglsYL 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 141 SYCIQNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISI----SETMWEVYFLVYSL----LSVIMI 212
Cdd:PRK06589  274 QRIFAEFNWLIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFIltpkALGAAILHLVSHSFakicLFYSMG 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 213 LLFNQSKLFFMNQIYTSENMNIEIKFLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVL----TTITLYY 288
Cdd:PRK06589  354 SIYSLKKEDQVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVMLVviasSILSALY 433

                         330
                  ....*....|....*..
gi 2088662739 289 YMRIMFSAMIMTFSENS 305
Cdd:PRK06589  434 LLKILSSIYKPSLSENS 450
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 95-297 9.46e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 43.79  E-value: 9.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  95 MISSSLLLKIGAAPFHFWFPEVMGATSWINCMMLMTWQKIAPMMVLSYCIQNS----MFISTIIIMSIAIGALGGLNQIS 170
Cdd:PRK07234  189 LIALGLLVKGGIFVSGLWLPLTHSEAEPPVSALLSGVVVKAGVFPLVRCALDVpgldLIVRIFGVGTALLGVLFALLEKD 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 171 LRQLMAYSSISHLGWMIASISISEtmwevyflVYSLLSVIMillfnQSKLFFMNQIYTSEN------MNIEIKFLMFLTL 244
Cdd:PRK07234  269 LKRMLAFSTISQLGFILAAPLVGG--------LYALAHGLV-----KSTLFLCAGALPSRNftelisQMLGIGKWIPLTM 335

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2088662739 245 --LSLGGLPPFLGFMPKWMVMQSMVEnNLSALMAIMTVLTTITLYYYMRIMFSAM 297
Cdd:PRK07234  336 asFSIAGFPLLAGFVSKVLTLKNLLP-WQAIALNLAAVGTAASFWKFIFLPFSAD 389
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 160-292 1.08e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 43.80  E-value: 1.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 160 IGALGGLNQISLRQLMAYSSISHLGWMIASISISETMW---EVYFLVYSLLSvimillfnQSKLFFMNQIYTSENMNIEI 236
Cdd:PRK12665  286 VGILGAIAQSDIKRLLSFTLVSHIGYMVFGIALSTVAGlsgAIYYVAHHITV--------QTTLFLVVGLIERQAGSSSL 357

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2088662739 237 K-------------FLMFLTLLSLGGLPPFLGFMPKWMVMQSMVENNLS---ALMAIMTVLTTITLYYYMRI 292
Cdd:PRK12665  358 RrlgglakaspllaVLFFVPALNLGGIPPFSGFIGKVALLEAGAEDGTWlawALVAGGVVTSLLTLYAVARV 429
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 57-293 1.98e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 43.06  E-value: 1.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  57 SIKYFIVQAMASTMLLFSILIIQLKYPLNWEQQIIPSMMISSSL--------------LLKIGAAPFHFWFPEV------ 116
Cdd:PRK08668  149 SLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADISQGLINDTSTgfalivflfllafgVAKAGIFPLHVWAPDAyseapq 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 117 ------------MGATSWINCMMLMTWQKIAPMMVLsycIQNSMFISTIII----MSIAIGALGGLNQISLRQLMAYSSI 180
Cdd:PRK08668  229 sfsavlsgqlskLGAYGFLLVLYVLPGTKLFSEFGT---YRGVPLFNYILAwlgnISIIVGTLMAILQEDIKKLIAYSSV 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 181 SHLGWMIASISISETmwevYFLVYSLLSVIMILLFnqSKLFFMNQ---IYTSENMNIE----------IKFLMFL-TLLS 246
Cdd:PRK08668  306 ANGGYILVGLGLGTS----LGFAGGLFHVFNHALF--KGLFFLIFaavIYRTGTTKISemggliekmpFTFAMYLvAIIS 379

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 2088662739 247 LGGLPPFLGFMPKWMVMQSMVENNLSALMAIMTVLTTITLYYYMRIM 293
Cdd:PRK08668  380 LAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPL 426
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 84-301 5.88e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 41.68  E-value: 5.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  84 LNWEQQIIPSMMISSSLLLKIGAA-------PFHFWFPEVM-----------GATswincM------MLMtwqKIAPMMV 139
Cdd:COG1009   198 LAAAPTILSSPLLTLILLLLLLGAfgksaqfPLHFWLPDAMegptpvsallhAAT-----MvkagvyLLA---RLSPLFA 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 140 LSYCIQnsMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVY-----SLL-----SV 209
Cdd:COG1009   270 LSPVWL--TVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVGAYVAALFHLLThaffkALLflgagSV 347

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 210 IMIL----LFNQSKLF-FMNQIYTsenmnieikfLMFLTLLSLGGLPPFLGFMPKWMVMQSMVE-NNLSALMAIMTVLT- 282
Cdd:COG1009   348 IHATgtrdIRKMGGLRkKMPITAI----------TFLIGALSLAGIPPFAGFFSKEAILEAALEaGGLGPLLLAVALLGa 417

                         250
                  ....*....|....*....
gi 2088662739 283 TITLYYYMRIMFsamiMTF 301
Cdd:COG1009   418 FLTAFYSFRLFF----LVF 432
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 84-222 7.56e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 37.81  E-value: 7.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739  84 LNWEQQIIPSMMISSSLLL------------KIGAAPFHFWFPEVMG-ATSWINCMMLMTWQKIAPMMVLSYCI------ 144
Cdd:PRK08676  188 LNWTELAAHASLLSPSVLGasflfifigflaKSGLVPFHTWLPAAYAkAPSVVSALLSGTVLNIGIYGILRLSAllrqsg 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2088662739 145 ---QNSMFISTIIIMSIAIGALGGLNQISLRQLMAYSSISHLGWMIASISISETMWEVYFLVYSLLSVIMillfnQSKLF 221
Cdd:PRK08676  268 aaeQFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHMLAHSLV-----KSGLF 342


                  .
gi 2088662739 222 F 222
Cdd:PRK08676  343 F 343
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH