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Conserved domains on  [gi|2070647664|gb|QXT45770|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Leucrocuta aphrodite]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009599)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 1-167 2.05e-29

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214445  Cd Length: 160  Bit Score: 105.66  E-value: 2.05e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664   1 MLMFSTLIVGFTFMTMNHPLAMGLVLLCQTLLVALFTGILAPSFWFSYILFLVFLGGMLVLFIYVTSLASNEMFSISSKS 80
Cdd:MTH00166    3 MLMMLLLILSIIFLFLNHPLSMGLILIIQTILISLLLGLMMKSFWFSYILFLIFLGGMLVLFIYITSLASNEKFKFSLKL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664  81 LMLIMAAAGLLIFFCLINDPLSwatpefpdqaVSSQACNPSNLANILVKLYSSPSYFLTLLLVSYLFLTLVAVVTITQIF 160
Cdd:MTH00166   83 LILFLLMLLLMLNNFIKNSEMS----------NFNNNFNFFENSFSLSKLYNFPTMLITLFMIIYLLLTLIVVVKITNIF 152


                  ....*..
gi 2070647664 161 EGPLRSK 167
Cdd:MTH00166  153 KGPLRSK 159
 
Name Accession Description Interval E-value
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 1-167 2.05e-29

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 105.66  E-value: 2.05e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664   1 MLMFSTLIVGFTFMTMNHPLAMGLVLLCQTLLVALFTGILAPSFWFSYILFLVFLGGMLVLFIYVTSLASNEMFSISSKS 80
Cdd:MTH00166    3 MLMMLLLILSIIFLFLNHPLSMGLILIIQTILISLLLGLMMKSFWFSYILFLIFLGGMLVLFIYITSLASNEKFKFSLKL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664  81 LMLIMAAAGLLIFFCLINDPLSwatpefpdqaVSSQACNPSNLANILVKLYSSPSYFLTLLLVSYLFLTLVAVVTITQIF 160
Cdd:MTH00166   83 LILFLLMLLLMLNNFIKNSEMS----------NFNNNFNFFENSFSLSKLYNFPTMLITLFMIIYLLLTLIVVVKITNIF 152


                  ....*..
gi 2070647664 161 EGPLRSK 167
Cdd:MTH00166  153 KGPLRSK 159
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
13-156 2.71e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 39.02  E-value: 2.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664  13 FMTMNHPLAMGLVLLCQTLLVALFTGILAPSFwFSYILFLVFLGGMLVLFIYVTSLASNEMFSISSKSLMLIMAAAGLLI 92
Cdd:pfam00499   3 VVTSRNPVHSALFLVLTFFGVAGLYLLLGAEF-LAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGLL 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2070647664  93 FFCLINDPLSWATPEFPDQAVSSQACNPSNLANILVKlysspSYFLTLLLVS-YLFLTLVAVVTI 156
Cdd:pfam00499  82 LLALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFT-----DYLLPFELASvLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 1-167 2.05e-29

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 105.66  E-value: 2.05e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664   1 MLMFSTLIVGFTFMTMNHPLAMGLVLLCQTLLVALFTGILAPSFWFSYILFLVFLGGMLVLFIYVTSLASNEMFSISSKS 80
Cdd:MTH00166    3 MLMMLLLILSIIFLFLNHPLSMGLILIIQTILISLLLGLMMKSFWFSYILFLIFLGGMLVLFIYITSLASNEKFKFSLKL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664  81 LMLIMAAAGLLIFFCLINDPLSwatpefpdqaVSSQACNPSNLANILVKLYSSPSYFLTLLLVSYLFLTLVAVVTITQIF 160
Cdd:MTH00166   83 LILFLLMLLLMLNNFIKNSEMS----------NFNNNFNFFENSFSLSKLYNFPTMLITLFMIIYLLLTLIVVVKITNIF 152


                  ....*..
gi 2070647664 161 EGPLRSK 167
Cdd:MTH00166  153 KGPLRSK 159
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 1-167 3.17e-13

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 63.49  E-value: 3.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664   1 MLMFSTLIVGFTFMTMNHPLAMGLVLLCQTLLVALFTGILApSFWFSYILFLVFLGGMLVLFIYVTSLASNEMFSISSKS 80
Cdd:MTH00212    5 LLLSLLLLLMLLFPLSAHPLTLGVSLLLSSLLSCLIITMES-NSWYGYILFLIYIGGLLVLFGYMVALSPNEHLFFKKYF 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664  81 LMLIMAAAGLLIFFCLINDPLSWATPEFpdqavssqacnPSNLANILVKLYSSPSYFLTLLLVSYLFLTLVAVVTITQIF 160
Cdd:MTH00212   84 KGFGMILISLNLYLLLMTLGSSNFSPML-----------NLKLELNVSKILSNNNIPILLFLGLILLIALLMVVKICQYY 152


                  ....*..
gi 2070647664 161 EGPLRSK 167
Cdd:MTH00212  153 KGPLRPF 159
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 1-165 2.39e-11

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 58.74  E-value: 2.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664   1 MLMFSTLIVGFTFMTMNHPLAMGLVLLCQTLLVALFTGILApSFWFSYILFLVFLGGMLVLFIYVTSLASNEMFSISSKS 80
Cdd:MTH00152    5 ILLSVCFSLFLLLPLSKQPLSLGLVLLLLSLFVCVEIGLTL-SSWYGYLLFLVYVGGLLVMFAYVVSLSPNPLFGSNFKF 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664  81 LMLIMAAAGLLIFFCLINDPLSwatpeFPDQAVSSQACNPSNLANILVKLYSSPSYFLTLLLVSYLFLTLVAVVTITQIF 160
Cdd:MTH00152   84 VFFSLTLFGFLGLFFFFLYLYS-----SGGLSLSSLFDGSSGSLSFGGGLYSSSGWSIFVFLAVLLLIVMVSVVKICYYE 158


                  ....*
gi 2070647664 161 EGPLR 165
Cdd:MTH00152  159 EGSLR 163
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
13-156 2.71e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 39.02  E-value: 2.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664  13 FMTMNHPLAMGLVLLCQTLLVALFTGILAPSFwFSYILFLVFLGGMLVLFIYVTSLASNEMFSISSKSLMLIMAAAGLLI 92
Cdd:pfam00499   3 VVTSRNPVHSALFLVLTFFGVAGLYLLLGAEF-LAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGLL 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2070647664  93 FFCLINDPLSWATPEFPDQAVSSQACNPSNLANILVKlysspSYFLTLLLVS-YLFLTLVAVVTI 156
Cdd:pfam00499  82 LLALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFT-----DYLLPFELASvLLLVALVGAIVL 141
ND6 MTH00015
NADH dehydrogenase subunit 6; Validated
 1-168 2.40e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 164590  Cd Length: 155  Bit Score: 36.76  E-value: 2.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664   1 MLMFSTLIVGFTFMTMNHPLAMGLVLLCQTLLVALfTGILAPSFWFSYILFLVFLGGMLVLFIYVTSLASNEMFSISSKS 80
Cdd:MTH00015    5 FFLILMISLTCSLFLATTPITLGINILMMALLLAT-TMASALSSWFAFLTFLIYVGGMLVMFAYFLALTPNQQLNLGPMA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2070647664  81 LMlimaaagLLIFFCLINDPLSWATPEFPDQAVSSQAcnpsnlaniLVKLYSSPSYFLTLLLVSYLFLTLVAVVTITQIF 160
Cdd:MTH00015   84 KY-------TLITLLTLSTTLKLTNPPSPSFFSSTQG---------NTFLYQPENAPLLIFLALILLLTMVIVVKLTRRS 147


                  ....*...
gi 2070647664 161 EGPLRSKH 168
Cdd:MTH00015  148 SGPLRPFK 155
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 21-70 5.42e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 35.50  E-value: 5.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2070647664  21 AMGLVLLCqtllvALFTGILAP---SFwFSYILFLVFLGGMLVLFIYVTSLAS 70
Cdd:MTH00138   29 ALGLVVVA-----GVGCGVLVGhggSF-LSLVLFLIYLGGMLVVFAYSAALAA 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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