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Conserved domains on  [gi|2065955867|gb|QXM27040|]
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NADH dehydrogenase subunit II (mitochondrion) [Emberizoides herbicola]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 5.03e-157

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 443.88  E-value: 5.03e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   1 MNPQASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQ 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  81 TGQWDITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLKLSTLMTAWAKTPPL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 241 STMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMTPTATLLSILSLLSLFFYLRLAYCTMITLPPHTTNHMKQWRTGKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 2065955867 321 TSTMIAVLTASSLMLLPISPMILTIV 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 5.03e-157

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 443.88  E-value: 5.03e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   1 MNPQASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQ 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  81 TGQWDITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLKLSTLMTAWAKTPPL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 241 STMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMTPTATLLSILSLLSLFFYLRLAYCTMITLPPHTTNHMKQWRTGKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 2065955867 321 TSTMIAVLTASSLMLLPISPMILTIV 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-276 4.18e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.64  E-value: 4.18e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  14 LLGTTITISSNHWVMAWAGLEINTLAVLPLIS-KSHHPRAIEAATKYFLTQAAASALVLF-SSMTNAwQTGQWDITQLTH 91
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIAA 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  92 PVS------------CLIFTSAIAMKLGLVPFHFWFPEVLQGSSlttglllstlmklPPIT-----------------LL 142
Cdd:COG1007   191 ALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAP-------------TPVTaflatapkiaafaallrLL 257

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 143 YMTSPSLNP---TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAV-IIIYNPN-LTLLNFYL--YAMMTTTV 215
Cdd:COG1007   258 VEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLgLAAGTPLgVSAALFYLlaYLFMNLGA 337

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2065955867 216 FLTLNTI-KVLKLSTLMTAWA----KTPPLSTMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMT 276
Cdd:COG1007   338 FAVILLLsRKGGEAEEIEDLAglarRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLY 403
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 4.52e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.61  E-value: 4.52e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  23 SNHWVMAWAGLEINTLAVLPLI-SKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  91 HPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPT------LLTTLAILSAAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 165 GGWMGLNQTQIRKILAFSSISHLGWMAVII----IYNPNLTLLNFYLYAMMTTTVFL-TLNTIKVLKLSTLMTA----WA 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcAGSVIYRRVHTRNIRDygglAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2065955867 236 KTPPLSTMLLLTLLSLAGLPPLTGFLPKWFILQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-275 2.68e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 82.69  E-value: 2.68e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  14 LLGTTITISSNHWVMAWAGLEINTLAVLPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  93 VSCLIFT------------SAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLP---PITLLYMTSPS----LNPTL 153
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFgfseAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 154 LTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGW--MAVIIIYNPNLTLLNFYL--YAMMTTTVFLTLNTIKVLKLS- 228
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYilIGLLAGTLEGIKAVLFYIfiYALMSLGAFGVLSLLRSYKDEw 351

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2065955867 229 ----TLMTAWAKTPPLSTMLLLTLL-SLAGLPPLTGFLPKWFILQELTKQDM 275
Cdd:TIGR01770 352 ieyiSDFAGLFKTNPILAILILIFMfSLAGIPPLAGFFGKFYVFFALLKSGL 403
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 5.03e-157

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 443.88  E-value: 5.03e-157
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   1 MNPQASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQ 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  81 TGQWDITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLKLSTLMTAWAKTPPL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 241 STMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMTPTATLLSILSLLSLFFYLRLAYCTMITLPPHTTNHMKQWRTGKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                         330       340
                  ....*....|....*....|....*.
gi 2065955867 321 TSTMIAVLTASSLMLLPISPMILTIV 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-346 1.66e-126

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 366.44  E-value: 1.66e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   1 MNPQASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQ 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  81 TGQWDITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSlNPTLLTTLAIL 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLKLSTLMTAWAKTPPL 240
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 241 STMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMTPTATLLSILSLLSLFFYLRLAYCTMITLPPHTTNHMKQWRTGKP 320
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                         330       340
                  ....*....|....*....|....*..
gi 2065955867 321 TSTM-IAVLTASSLMLLPISPMILTIV 346
Cdd:MTH00135  320 QLTLpLAISTTATLMLLPLTPAILALL 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-345 1.19e-125

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 364.24  E-value: 1.19e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   1 MNPQASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQ 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  81 TGQWDITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLKLSTLMTAWAKTPPL 240
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 241 STMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMTPTATLLSILSLLSLFFYLRLAYCTMITLPPHTTNHMKQWRTGKP 320
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320

                         330       340
                  ....*....|....*....|....*
gi 2065955867 321 TSTMIAVLTASSLMLLPISPMILTI 345
Cdd:MTH00070  321 TNNLLSLTIILSLMLLPITPTILNL 345
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-345 3.51e-110

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 324.88  E-value: 3.51e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   1 MNPQASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQ 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  81 TGQWDITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLKLSTLMTAWAKTPPL 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 241 STMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMTPTATLLSILSLLSLFFYLRLAYCTMITLPPhTTNHMK---QWRT 317
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFP-STNNMKmkwQFEN 319

                         330       340
                  ....*....|....*....|....*...
gi 2065955867 318 GKPTsTMIAVLTASSLMLLPISPMILTI 345
Cdd:MTH00105  320 TKPM-TLLPTLIILSTMLLPLTPMLSIL 346
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-345 1.11e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 282.63  E-value: 1.11e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   1 MNPQASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQ 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  81 TGQWDITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLKLSTLMTAWAKTPPL 240
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 241 STMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMTPTATLLSILSLLSLFFYLRLAYCTMITLPPHTTNHMKQWRTGKP 320
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                         330       340
                  ....*....|....*....|....*
gi 2065955867 321 TSTMIAVLTASSLMLLPISPMILTI 345
Cdd:MTH00200  321 SNLLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-267 1.04e-72

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 229.05  E-value: 1.04e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   1 MNPQASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQ 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  81 TGQWDITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAIL 160
Cdd:MTH00041   81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLKLSTLMTAWAKTPPL 240
Cdd:MTH00041  161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                         250       260
                  ....*....|....*....|....*..
gi 2065955867 241 STMLLLTLLSLAGLPPLTGFLPKWFIL 267
Cdd:MTH00041  241 AFLFILSILSLGGLPPLTGFLNKFISL 267
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-345 4.68e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 170.00  E-value: 4.68e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   1 MNPQASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWq 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  81 tgqwdITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTspsLNPTLLTTLAIL 160
Cdd:MTH00160   81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 161 SAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLKLSTLMTAWAKTPPL 240
Cdd:MTH00160  153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 241 STMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMTPTATLLSILSLLSLFFYLRLAYCTMITLPPHTTNHMKQwrTGKP 320
Cdd:MTH00160  233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKK--KKNK 310

                         330       340
                  ....*....|....*....|....*
gi 2065955867 321 TSTMIAVLTASSLMLLPISPMILTI 345
Cdd:MTH00160  311 FSLILNFLSFISLFGLILSSLLFLL 335
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 5-275 2.64e-43

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 152.35  E-value: 2.64e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   5 ASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQW 84
Cdd:MTH00144    5 SNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  85 DITqlthpvscLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNP-TLLTTLAILSAA 163
Cdd:MTH00144   85 FSM--------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSAL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 164 LGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTiKVLKLSTLMTAWAKTPPLSTM 243
Cdd:MTH00144  157 VGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWS-GDSGSMKDLGSLKPSYKTGLS 235

                         250       260       270
                  ....*....|....*....|....*....|..
gi 2065955867 244 LLLTLLSLAGLPPLTGFLPKWFILQELTKQDM 275
Cdd:MTH00144  236 IISLLLSLGGLPPFLGFCSKLLVLISSMESSP 267
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-275 1.38e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 150.32  E-value: 1.38e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   6 SLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSmtnawqTGQWD 85
Cdd:MTH00011    8 MFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  86 ITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAILSAALG 165
Cdd:MTH00011   82 FPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 166 GWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLKLSTLMTAWAKTPPLSTMLL 245
Cdd:MTH00011  162 GLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLF 241

                         250       260       270
                  ....*....|....*....|....*....|
gi 2065955867 246 LTLLSLAGLPPLTGFLPKWFILQELTKQDM 275
Cdd:MTH00011  242 IMLLSLGGLPPFTGFMPKLMAIETLTSNSM 271
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-270 2.81e-37

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 136.34  E-value: 2.81e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   8 IFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQTgqwdit 87
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL------ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  88 qLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLymTSPSLNPTLLTTLAILSAALGGW 167
Cdd:MTH00197   76 -YLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL--AFNSSSFMGLLICSVLSSLIGGI 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 168 MGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLKLSTLMTAWAKTPPLSTMLLLT 247
Cdd:MTH00197  153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                         250       260
                  ....*....|....*....|...
gi 2065955867 248 LLSLAGLPPLTGFLPKWFILQEL 270
Cdd:MTH00197  233 FLSLGGLPPLSGFFLKWLILTSL 255
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 14-276 4.18e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 93.64  E-value: 4.18e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  14 LLGTTITISSNHWVMAWAGLEINTLAVLPLIS-KSHHPRAIEAATKYFLTQAAASALVLF-SSMTNAwQTGQWDITQLTH 91
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIAA 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  92 PVS------------CLIFTSAIAMKLGLVPFHFWFPEVLQGSSlttglllstlmklPPIT-----------------LL 142
Cdd:COG1007   191 ALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAP-------------TPVTaflatapkiaafaallrLL 257

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 143 YMTSPSLNP---TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAV-IIIYNPN-LTLLNFYL--YAMMTTTV 215
Cdd:COG1007   258 VEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLgLAAGTPLgVSAALFYLlaYLFMNLGA 337

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2065955867 216 FLTLNTI-KVLKLSTLMTAWA----KTPPLSTMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMT 276
Cdd:COG1007   338 FAVILLLsRKGGEAEEIEDLAglarRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLY 403
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 4.52e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.61  E-value: 4.52e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  23 SNHWVMAWAGLEINTLAVLPLI-SKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  91 HPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPT------LLTTLAILSAAL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 165 GGWMGLNQTQIRKILAFSSISHLGWMAVII----IYNPNLTLLNFYLYAMMTTTVFL-TLNTIKVLKLSTLMTA----WA 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcAGSVIYRRVHTRNIRDygglAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2065955867 236 KTPPLSTMLLLTLLSLAGLPPLTGFLPKWFILQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-267 8.98e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 88.93  E-value: 8.98e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  13 LLLGTTITISSNHWVMAWAGLEINTLAVLPLI-SKSHHPRAIEAATKYFLTQAAASALVLFS-------------SMTNA 78
Cdd:MTH00196    2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  79 WQTGQWDITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNptLLTTLA 158
Cdd:MTH00196   82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 159 ILSAALGGWMGLNQTQIRKILAFSSISHLGW----MAVIIIYNPNLTLLNFYLYAMMTTTVFLTLNTIKVLK--LSTLMT 232
Cdd:MTH00196  160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFvlwgIEIGSFESIQASLVYLFIYIIMSICVFSIILALNVYKnlIIEFSG 239

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2065955867 233 AWAKTPPLSTMLLLTLLSLAGLPPLTGFLPKWFIL 267
Cdd:MTH00196  240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 4-267 1.18e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 86.61  E-value: 1.18e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   4 QASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQTG 82
Cdd:MTH00199   97 QSSPILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTG 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  83 QWDI----TQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTtlA 158
Cdd:MTH00199  177 ETSIqginSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--A 254

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 159 ILSAALGGWMGLNQTQIRKILAFSSISHLGWM--AVIIIYNPNL--TLLNFYLYAMMTTTVFLTLNTIKVLK--LSTLMT 232
Cdd:MTH00199  255 VLSIIYGAIGALNQTKIKRLLAYSGIGHMGFIlfGVAIGSFESIqaSLIYMIIYVIMSICSFSIILSLKLTKglIVEVSG 334

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 2065955867 233 AWAKTPPLSTMLLLTLLSLAGLPPLTGFLPKWFIL 267
Cdd:MTH00199  335 LSRKNPVIALTLALTFLSIAGIPPLAGFLSKWLIL 369
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-279 2.44e-18

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 85.64  E-value: 2.44e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  14 LLGTTITISSNHWVMAWAGLEINTLAVLPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQWDITQLTHP 92
Cdd:PRK05777  113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKA 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  93 VS------------CLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKL----PPITLLYMTSPSLNPT---L 153
Cdd:PRK05777  193 LAdgsgnsllllfgLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGLSEDwqqV 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 154 LTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTL--LNFYL--YAMMTTTVFLTLNTI-KVLKLS 228
Cdd:PRK05777  273 LAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYsaVLFYLlaYLFMTLGAFGVISLLrRKGGEA 352

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2065955867 229 TLMTAWA----KTPPLSTMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMTPTA 279
Cdd:PRK05777  353 ESISDFAglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLA 407
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 14-275 2.68e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 82.69  E-value: 2.68e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  14 LLGTTITISSNHWVMAWAGLEINTLAVLPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  93 VSCLIFT------------SAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLP---PITLLYMTSPS----LNPTL 153
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFgfseAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 154 LTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGW--MAVIIIYNPNLTLLNFYL--YAMMTTTVFLTLNTIKVLKLS- 228
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYilIGLLAGTLEGIKAVLFYIfiYALMSLGAFGVLSLLRSYKDEw 351

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2065955867 229 ----TLMTAWAKTPPLSTMLLLTLL-SLAGLPPLTGFLPKWFILQELTKQDM 275
Cdd:TIGR01770 352 ieyiSDFAGLFKTNPILAILILIFMfSLAGIPPLAGFFGKFYVFFALLKSGL 403
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 3-267 5.60e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 72.97  E-value: 5.60e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   3 PQASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAI---------EAATKYFLTQAAASALVLFS 73
Cdd:MTH00198  187 PRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFG 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  74 SMTNAWQTGQ--------------WDITQLTHPVSCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPI 139
Cdd:MTH00198  267 CALYFGFTGNegmlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVY 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 140 TLLymTSPSLNPTLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLYAMM-------T 212
Cdd:MTH00198  347 ILL--TSLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTylvsalaS 424

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2065955867 213 TTVFLTL------------------NTIKVLKLSTLMTAWAKTPPLSTMLLLTLLSLAGLPPLTGFLPKWFIL 267
Cdd:MTH00198  425 FTVICTLeefgtrtptsrqrdgsfgNYNLVRRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 13-268 4.08e-13

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 69.79  E-value: 4.08e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  13 LLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQWDITQLTHP 92
Cdd:COG0651   116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAAR 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  93 VS----------CLIFTSAIAMKLGLVPFHFWFPEVlqgsslttglllstlMKLPP----------------------IT 140
Cdd:COG0651   196 LAeldpglllaaFALLLVGFGIKAALFPLHFWLPDA---------------YPAAPspvsallsglltkvgvyailrvLT 260

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 141 LLYMTSPSLNP-TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLY----AMMTTTV 215
Cdd:COG0651   261 LLFGADPALFLgTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHllnhALAKALL 340

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2065955867 216 FLTLNTIKVL----KLSTLMTAWAKTPPLSTMLLLTLLSLAGLPPLTGFLPKWFILQ 268
Cdd:COG0651   341 FLAAGAIERAtgtrDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQ 397
ndhB CHL00049
NADH dehydrogenase subunit 2
 1-263 5.39e-10

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 60.40  E-value: 5.39e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   1 MNPQASLIFTISLLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHP-RAIEAATKYFLTQAAASALVL--FSSM-- 75
Cdd:CHL00049  108 MAITEFLLFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSGYTKKDvRSNEATMKYLLMGGASSSILVygFSWLyg 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  76 TNAWQTGQWDI------TQLTHPVSCLI----FTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITL---- 141
Cdd:CHL00049  188 LSGGEIELQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALatri 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 142 LYMTSPSLNP---TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAV-IIIYNPNLTllnfylYAMMTTT--- 214
Cdd:CHL00049  268 FDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIgIIVGDSNDG------YASMITYmlf 341

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 215 -VFLTLNTIKVLKLSTLMTA----------WAKTPPLSTMLLLTLLSLAGLPPLTGFLPK 263
Cdd:CHL00049  342 yIFMNLGTFACIVLFGLRTGtdnirdyaglYTKDPFLALSLALCLLSLGGIPPLAGFFGK 401
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-266 1.37e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 56.21  E-value: 1.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  50 PRAIEAATKYFLTQAAASALVLF---------------SSMTNAWQTGQWDITQLThpvscLIFTSA-IAMKLGLVPFHF 113
Cdd:PRK02504  157 PRSNEAALKYLLIGAASSAIFLYgssllyglsggstqlSAIALALITSPSLGLALA-----LVFVIAgIAFKISAVPFHQ 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 114 WFPEVLQGSSLTTGLLLSTLMKLP----PITLLYMTSPSLNP---TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISH 186
Cdd:PRK02504  232 WTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDEqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQ 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 187 LGWMAVIIIYNPNLTLLNFYLYamMTTTVFLTLNTIKVLKLSTLMTA----------WAKTPPLSTMLLLTLLSLAGLPP 256
Cdd:PRK02504  312 AGFVMIGLVAGTEAGYASMVFY--LLAYLFMNLGAFACVILFSLRTGtdqisdyaglYQKDPLLTLGLSLCLLSLGGIPP 389

                         250
                  ....*....|
gi 2065955867 257 LTGFLPKWFI 266
Cdd:PRK02504  390 LAGFFGKIYL 399
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-266 3.56e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 54.72  E-value: 3.56e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  33 LEINTLAVLPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQWDITQLTHPVS----------CLIFTSA 101
Cdd:PRK08376  150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGIALLYGQYGTLNMAYLAVKMSenptvvakiaLALFIAG 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 102 IAMKLGLVPFHFWFPEVlQGSSLTTGLLLSTLMKLPPITLLY-----MTSPSLNPT----LLTTLAILSAALGGWMGLNQ 172
Cdd:PRK08376  230 LAMKSGAVPVHMWLPDA-YPAAPSSISAMLLVIKQAGLYALArvlfsIYGPAINLAtvgwVIIILGCLTMFVGVAMAVVQ 308

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 173 TQIRKILAFSSISHLGWM------AVIIIYNPNLT----------LLNFYLYAMMTTTVFLT-------LNTIKVLKLST 229
Cdd:PRK08376  309 KDVKRLLAYHSVSQIGYMllglgvGLAALGDPAMAsygeialaggIYHIVNHALYKALLFLTagaviyeTGTRNLNELGG 388

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 2065955867 230 LmtawAKTPPLSTMLLLT-LLSLAGLPPLTGFLPKWFI 266
Cdd:PRK08376  389 L----ARTMPKTTIAFLIgAAAIVGLPPFNGFASKWLI 422
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 96-263 2.63e-07

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 52.23  E-value: 2.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  96 LIFTSAIAmKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLL------YMTSPSLNPTLLTtLAILSAALGGWMG 169
Cdd:PRK12644  208 LILVGALS-KSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVarlapgFADVPVWRPTVLV-LGLATMLLGGWRA 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 170 LNQTQIRKILAFSSISHLGWMAVII-IYNPNLTLLNFYL---YAMMTTTVFLTLNTI-------KVLKLSTLmtaWAKTP 238
Cdd:PRK12644  286 LRQHDLKLILAYGTVSQLGFLTVLVgIGTRDAALAGLAMllaHALFKAALFLVVGIIdhstgtrDIRKLSGL---GRRQP 362

                         170       180
                  ....*....|....*....|....*
gi 2065955867 239 PLSTMLLLTLLSLAGLPPLTGFLPK 263
Cdd:PRK12644  363 VLAVVAALAAASMAGLPPLLGFVAK 387
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-188 6.77e-07

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 50.85  E-value: 6.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  49 HPRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQW--DITQLTH-----PVSCLIFTS---AIAMKLGLVPFHFWFPEV 118
Cdd:COG1008   156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAaplplTAQLLLFLAffiAFAVKVPMFPFHTWLPDA 235

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2065955867 119 L-QGSSLTTGLLLSTLMKLP-------PITLLYMTSPSLNPTLLTtLAILSAALGGWMGLNQTQIRKILAFSSISHLG 188
Cdd:COG1008   236 HvEAPTAGSVLLAGVLLKMGgygllrfALPLFPEASAYFAPLLAA-LGVIGIIYGALVALAQTDLKRLIAYSSVSHMG 312
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-194 1.73e-06

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 49.55  E-value: 1.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  50 PRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQ-WDITQL-THPVSC-------LIFTSAIAMKLGLVPFHFWFPEV-L 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLELlNLPLPFgvqtwlfLAFFIAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 120 QGSSLTTGLLLSTLMKLPP-------ITLLYMTSPSLNPtLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAV 192
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTygflrfnLPLFPDASLYFAP-VLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLL 310


                  ..
gi 2065955867 193 II 194
Cdd:TIGR01972 311 GI 312
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 34-279 2.70e-06

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 48.84  E-value: 2.70e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  34 EINTLAVLPLISKSHHpRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQWDIT-------QLTHPVSCLIFT----SAI 102
Cdd:PRK08668  128 EIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFAdisqgliNDTSTGFALIVFlfllAFG 206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 103 AMKLGLVPFHFWFPEV------------------LQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNpTLLTTLAILSAAL 164
Cdd:PRK08668  207 VAKAGIFPLHVWAPDAyseapqsfsavlsgqlskLGAYGFLLVLYVLPGTKLFSEFGTYRGVPLFN-YILAWLGNISIIV 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 165 GGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLT----LLNFYLYAMMTTTVFLTLNTI----KVLKLSTLMTAWAK 236
Cdd:PRK08668  286 GTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGfaggLFHVFNHALFKGLFFLIFAAViyrtGTTKISEMGGLIEK 365

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2065955867 237 TPPLSTMLLLTLLSLAGLPPLTGFLPKWFILQELTKQDMTPTA 279
Cdd:PRK08668  366 MPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITA 408
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 7-192 5.68e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 44.76  E-value: 5.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   7 LIFTISLLLgttITISSNHWVMaWAGLEINTLAVLPLISKSHH-PRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQWD 85
Cdd:COG1009   118 LLFMAAMLG---LVLSDNLLLL-FVFWELVGLCSYLLIGFWYEkPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLN 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  86 ITQLTH------------PVSCLIFTSAIAmKLGLVPFHFWFPEvlqgsslttglllstLMKLP-PI-TLL--------- 142
Cdd:COG1009   194 FSELLAaaptilssplltLILLLLLLGAFG-KSAQFPLHFWLPD---------------AMEGPtPVsALLhaatmvkag 257

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2065955867 143 -YM---TSP--SLNPTLLTTLAILSAA---LGGWMGLNQTQIRKILAFSSISHLGWMAV 192
Cdd:COG1009   258 vYLlarLSPlfALSPVWLTVVAIIGAItalFAALIALAQTDIKRVLAYSTVSQLGYMFL 316
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 295-340 9.09e-05

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 39.55  E-value: 9.09e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2065955867 295 RLAYCTMITLPPHTTNHMKQWRTGKP-TSTMIAVLTASSLMLLPISP 340
Cdd:pfam06444   5 RLSYSTTLTLFPNTNNSKMKWRFNSTkNTLLLPTLTTLSILLLPLTP 51
PRK12650 PRK12650
DUF4040 family protein;
87-263 9.24e-05

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 44.26  E-value: 9.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  87 TQLTHPVSCLIFTSAIAmKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSL--NPT---LLTTLAILS 161
Cdd:PRK12650  204 PGLTTVVAVLIAVAAFT-KSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFhdVAVwnwLLIIVGMIT 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 162 AALGGWMGLNQTQIRKILAFSSISHLGWM-AVIIIYNP---NLTLLNFYLYAMMTTTVFLTLNTIK----VLKLSTLMTA 233
Cdd:PRK12650  283 ALMGAVFAVQKTDLKKLTAYSTVSQLGWIvATIGVGTPfalTAAVVHTLAHALFKSSLFMLIGVVDhqagTRDIRRLGSL 362

                         170       180       190
                  ....*....|....*....|....*....|
gi 2065955867 234 WAKTPPLSTMLLLTLLSLAGLPPLTGFLPK 263
Cdd:PRK12650  363 WRRMPFTFVSVTIAALSMAAVPPLFGFVSK 392
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 48-263 1.45e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 43.66  E-value: 1.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  48 HHPRAIEAATKYFLTQAAASALVLFSSMTNAWQTGQWDITQLTHPVS---------------CLIFTSAiAMKLGLVPFH 112
Cdd:PRK12649  156 HRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDSElienikghplflitlILIFIGA-AAKSAQGPFY 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 113 FWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPT-----LLTTLAILSAALGGWMGLNQTQIRKILAFSSISHL 187
Cdd:PRK12649  235 IWLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPIFSGTeawfiLVSGTGMITMVLAGFLAFRQTDIKAILAYSTISQL 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 188 GWMAVIIIYN----PNLTLL--NFYL--YAMMTTTVFLTLN-------TIKVLKLSTLMTawaKTPPLSTMLLLTLLSLA 252
Cdd:PRK12649  315 AYLMTMYGYTtyhePGLGVAaaTFHLlnHATFKACLFLVAGivaheaaTRDIRKLGGLRK---EMPITFIVASIAALAMA 391

                         250
                  ....*....|.
gi 2065955867 253 GLPPLTGFLPK 263
Cdd:PRK12649  392 GIPPLNGFLSK 402
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 109-267 1.56e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 43.37  E-value: 1.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 109 VPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPTLL--TTLAILSAA---LGGWMGLNQTQIRKILAFSS 183
Cdd:PRK12647  212 FPFHFWLPNAMEAPTPVSAYLHSATMVKAGIYLLARLNPVLGGTPLwqTILPLFGGLtmlTGALLAVRQTDLKLILAYST 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 184 ISHLGWMAVIIIYNPNLTLLNFYLY----AMMTTTVFLTLNTIK-------VLKLSTLMTAwakTPPLSTMLLLTLLSLA 252
Cdd:PRK12647  292 VSALGTLVMLLGLGSELAIKAAVLFlvahSLYKGALFMVAGIIDhetgtrdITKLGGLRRA---MPITAAAALLAALSMA 368

                         170
                  ....*....|....*
gi 2065955867 253 GLPPLTGFLPKWFIL 267
Cdd:PRK12647  369 GLPPLFGFLAKELIY 383
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 13-194 2.05e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 42.82  E-value: 2.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  13 LLLGTTITISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAA------SALVLFSSMTNAWQTGQWDI 86
Cdd:PRK08676  111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  87 TQLTHPV----------SCLIFTSAIAMKLGLVPFHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPT---- 152
Cdd:PRK08676  191 TELAAHAsllspsvlgaSFLFIFIGFLAKSGLVPFHTWLPAAYAKAPSVVSALLSGTVLNIGIYGILRLSALLRQSgaae 270

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2065955867 153 ----LLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAVII 194
Cdd:PRK08676  271 qfsnVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGI 316
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 142-267 2.16e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 42.80  E-value: 2.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 142 LYMTSPSLNpTLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAVIIIYNPNLTLLNFYLY----AMMTTTVFL 217
Cdd:PRK12662  271 FVFTTLPFN-NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYivnhSIVKSALFM 349

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2065955867 218 TLNTIK----VLKLSTLMTAWAKTPPLSTMLLLTLLSLAGLPPLTGFLPKWFIL 267
Cdd:PRK12662  350 VSGSISyhfgTTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-270 3.03e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 42.56  E-value: 3.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  33 LEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFS-SMTNAwQTGQWDITQLT------HPVSC--LIFTSAIA 103
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvGLLYG-VTGTLNMADLAgalaenPTVVTafGFVLLALA 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 104 MKLGLVPFHFWFPE-----------VLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNpTLLTTLAILSAALGGWMGLNQ 172
Cdd:PRK08375  214 LKAAVFPLHTWLPRaypaappvvtaLLSGLVTKVAVYALIRIYFTVFGGDFRFALGLG-WLLAVLALLSMLVGSLAALGQ 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 173 TQIRKILAFSSISHLGWMAVIIIYNPNLTLLN--FYL--YAMMTTTVFLTLNTIKVL----KLSTLMTAWAKTPPLSTML 244
Cdd:PRK08375  293 DDVKRVLAYSTVSQMGYILLGLALLTPLALAAglLHLlhHALMKGALFLAAGAIEVTygtrRLSELSGLGRRMPLTAAAF 372

                         250       260
                  ....*....|....*....|....*.
gi 2065955867 245 LLTLLSLAGLPPLTGFLPKWFILQEL 270
Cdd:PRK08375  373 AVASLSLIGVPPTSGFVSKWYLVVGA 398
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 8-192 3.96e-04

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 42.22  E-value: 3.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867   8 IFTISLLLgttiTISSNHWVMAWAGLEINTLAVLPLISKSHHPRAIEAATKYFLTQAAASALVLFSSM---TNAWqtgqw 84
Cdd:PRK06458  116 LFLFTMLL----ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTIlvyANAA----- 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  85 diTQLTHPVSCLIFTSAIAM----------------------KLGLVPFHFWFPE-----------VLQGSSLTTGLLLS 131
Cdd:PRK06458  187 --TVMGDGEMAILWTELLKHaslldptlmklafvflligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAV 264

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2065955867 132 TLMKlppITLLYMTSPSLNPTLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLGWMAV 192
Cdd:PRK06458  265 LRYY---ILIDAAIGSDFPGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
96-268 4.94e-04

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 41.86  E-value: 4.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  96 LIFTSAIAMKLGLVPFhFWFPEVLQGSSLTTGLLLSTLMKLPPI-------TLLYMTSPSLNPTLLTTLAILSAALGGWM 168
Cdd:PRK12663  211 LLFLLAFGMKAALFPF-MWLPAAYHTPNTEVAALFAALLTKVGIyalirvfTLLFPQERELLHPLLATMAAITMVIGALG 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 169 GLNQTQIRKILAFSSISHLGWM-AVIIIYNPN-LTLLNFYLYAMMT--TTVFLTLNTIKVL----KLSTLMTAWAKTPPL 240
Cdd:PRK12663  290 ALAYKDIRRIAGYQVISSIGFIlLGLALGTPAgINGAIFYLVHDMVvkTALFLIAGSLVRLtgyrSLQYLGGLYRKEPLF 369

                         170       180
                  ....*....|....*....|....*...
gi 2065955867 241 STMLLLTLLSLAGLPPLTGFLPKWFILQ 268
Cdd:PRK12663  370 GALFLILIFAIGGLPPFSGFWGKVLLVQ 397
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-188 6.99e-04

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 41.34  E-value: 6.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867  50 PRAIEAATKYFLTQAAASALVLFSSMT----NAWQTGQWDITQL-THPVSC-------LIFTSAIAMKLGLVPFHFWFPE 117
Cdd:PRK05846  157 KNRIYAATKFFLYTLLGSLLMLVAIIYlvvvYYNATGTFDIADLlNLPLPPgvqywlfLAFFIAFAVKMPMFPLHTWLPD 236

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2065955867 118 V-LQGSSLTTGLLLSTLMKLPPITLLYMTSPsLNP-------TLLTTLAILSAALGGWMGLNQTQIRKILAFSSISHLG 188
Cdd:PRK05846  237 AhVQAPTAGSVLLAGILLKMGAYGLLRFSLP-LFPdashefaPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMG 314
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 105-271 1.65e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 40.33  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 105 KLGLvpfHFWFPEVLQGSSLTTGLLLSTLMKLPPITLLYMTSPSLNPTLLTTLAI-----LSAALGGWMGLNQTQIRKIL 179
Cdd:MTH00032  241 QLGL---HTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPLFEKAPLTLLIItifgaLTAFFAATVGLVQNDLKKVI 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065955867 180 AFSSISHLGWMAVIIIY--NPNLTLLNFYLYAMMTTTVFLTLNTI---------KVLKLSTLMTAwakTPPLSTMLLLTL 248
Cdd:MTH00032  318 AYSTCSQLGYMVLIIGIegSHNVGLFHLVNHAFFKALLFLSAGSVihsttvdeqDMRKMGGLIHS---IPFTYTMMLIGS 394

                         170       180
                  ....*....|....*....|...
gi 2065955867 249 LSLAGLPPLTGFLPKWFILqELT 271
Cdd:MTH00032  395 FSIMGLPYLTGFYSKDLIL-ELT 416
PRK06590 PRK06590
NADH:ubiquinone oxidoreductase subunit L; Reviewed
 148-190 6.52e-03

NADH:ubiquinone oxidoreductase subunit L; Reviewed


Pssm-ID: 235836 [Multi-domain]  Cd Length: 624  Bit Score: 38.22  E-value: 6.52e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2065955867 148 SLNPTLLTTLAILSAA---LGGWMGLNQTQIRKILAFSSISHLGWM 190
Cdd:PRK06590  275 ELSPEALLFVAIVGAVtalFAAFIGLVQTDIKRVLAYSTMSQLGYM 320
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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