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Conserved domains on  [gi|2065889770|gb|KAG7652638|]
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Phospholipid/glycerol acyltransferase [Arabidopsis thaliana x Arabidopsis arenosa]

Protein Classification

glycerol-3-phosphate acyltransferase( domain architecture ID 10168560)

glycerol-3-phosphate acyltransferase (GPAT) catalyzes the incorporation of an acyl group from acylCoA into the acceptor glycerol 3-phosphate

CATH:  1.10.1200.50
EC:  2.3.1.-
Gene Ontology:  GO:0008374
SCOP:  4003349

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 140-377 1.75e-85

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


:

Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 258.69  E-value: 1.75e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 140 RVLLFVFGFYWIHESCPDRDsdmdsnpkttsteinqkgeaateePERPGAIVSNHVSYLDILYHMSASFPSFVAKRSVGK 219
Cdd:cd07991     2 RVLLFAFGFYVIKVHGKPDP------------------------PEAPRIIVANHTSFIDPLILFSDLFPSIVAKKELGK 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 220 LPLVGLISKCLGCVYVQREakspDFKGVSGTVNERVREAHSnKSAPTIMLFPEGTTTNGDYLLTFKTGAFLAGTPVLPVI 299
Cdd:cd07991    58 LPFIGTILRALGCIFVDRS----EPKDRKKVVEEIKERATD-PNWPPILIFPEGTTTNGKALIMFKKGAFEPGVPVQPVA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 300 LKYPYeRFSVAWDTISGA---RHILFLLCQFVNHLEVIRLPVYYPSqEEKDDPKLYASNVRKLMATEGNLILSELGLSDK 376
Cdd:cd07991   133 IRYPN-KFVDAFWNSSGYsslMYLFRLLTQPANVLEVEFLPVYTPS-EEGEDPKEFANRVRLIMANKLGLPATDWTGEDK 210


                  .
gi 2065889770 377 R 377
Cdd:cd07991   211 R 211
 
Name Accession Description Interval E-value
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 140-377 1.75e-85

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 258.69  E-value: 1.75e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 140 RVLLFVFGFYWIHESCPDRDsdmdsnpkttsteinqkgeaateePERPGAIVSNHVSYLDILYHMSASFPSFVAKRSVGK 219
Cdd:cd07991     2 RVLLFAFGFYVIKVHGKPDP------------------------PEAPRIIVANHTSFIDPLILFSDLFPSIVAKKELGK 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 220 LPLVGLISKCLGCVYVQREakspDFKGVSGTVNERVREAHSnKSAPTIMLFPEGTTTNGDYLLTFKTGAFLAGTPVLPVI 299
Cdd:cd07991    58 LPFIGTILRALGCIFVDRS----EPKDRKKVVEEIKERATD-PNWPPILIFPEGTTTNGKALIMFKKGAFEPGVPVQPVA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 300 LKYPYeRFSVAWDTISGA---RHILFLLCQFVNHLEVIRLPVYYPSqEEKDDPKLYASNVRKLMATEGNLILSELGLSDK 376
Cdd:cd07991   133 IRYPN-KFVDAFWNSSGYsslMYLFRLLTQPANVLEVEFLPVYTPS-EEGEDPKEFANRVRLIMANKLGLPATDWTGEDK 210


                  .
gi 2065889770 377 R 377
Cdd:cd07991   211 R 211
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 190-302 1.95e-25

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 99.74  E-value: 1.95e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770  190 IVSNHVSYLDILYHMSASF-----PSFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDfkgvSGTVNERVREAHSNKSa 264
Cdd:smart00563   3 VVANHQSFLDPLVLSALLPrklgrVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKA----RAALREAVELLKEGEW- 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 2065889770  265 ptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVILKY 302
Cdd:smart00563  78 --LLIFPEGTRSRPGKLLPFKKGAARlaleAGVPIVPVAIRG 117
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 184-363 7.92e-25

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 100.85  E-value: 7.92e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 184 PERPGAIVSNHVSYLDILYhMSASFP---SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDFKgvsgTVNERVREAHS 260
Cdd:COG0204    41 ADGPVLIVANHQSWLDILL-LLAALPrpvRFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAALR----ALRQAVEALKA 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 261 NKSaptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVILKYPYERFSvaWDTISGARHIlfllcqfvnhlEVIRL 336
Cdd:COG0204   116 GES---LVIFPEGTRSPDGRLLPFKTGAARlaleAGVPIVPVAIDGTERALP--KGFLPRPGKV-----------TVRIG 179

                         170       180
                  ....*....|....*....|....*..
gi 2065889770 337 PVYYPSQEEKDDPKLYASNVRKLMATE 363
Cdd:COG0204   180 PPIDPSDLEGEDRRELAERLRAAIEAL 206
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 184-301 3.31e-21

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 88.49  E-value: 3.31e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 184 PERPGAIVSNHVSYLD------ILYHMSASfPSFVAKRSVGKLPLVGLISKCLGCVYVQREakspDFKGVSGTVNERVRE 257
Cdd:pfam01553  12 RGGPAIVVANHQSYLDvlllslALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDRK----NRKDAAGTLEYLVEL 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2065889770 258 AHSNKSaptIMLFPEGTTTNGDYLLTFKTGAF----LAGTPVLPVILK 301
Cdd:pfam01553  87 LREGKL---VVIFPEGTRSREGELLPFKKGAFrlaiEAGVPIVPVAIS 131
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 184-300 1.72e-20

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 86.63  E-value: 1.72e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 184 PERPGAIV-SNHVSYLDILYhMSASFP---SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDfkgvsGTVNERVREAH 259
Cdd:TIGR00530  13 PAKSPVLVvANHQSNLDPLT-LSAAFPppiVFIAKKELKWIPFFGIMLWLTGAIFIDRENIRAI-----ATALKAAIEVL 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2065889770 260 SNKSAptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVIL 300
Cdd:TIGR00530  87 KQGRS--IGVFPEGTRSRGRDILPFKKGAFHiaikAGVPILPVVL 129
PLN02833 PLN02833
glycerol acyltransferase family protein
 186-366 3.05e-11

glycerol acyltransferase family protein


Pssm-ID: 215447  Cd Length: 376  Bit Score: 64.41  E-value: 3.05e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 186 RPGAI-VSNHVSYLD--ILYHMSAsFpSFVAKRSVGklpLVGLISK----CLGCVYVQR-EAKSPDfkgvsgTVNERVRE 257
Cdd:PLN02833  162 RPKQVfVANHTSMIDfiVLEQMTP-F-AVIMQKHPG---WVGFLQNtileSVGCIWFNRtEAKDRE------VVAKKLRD 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 258 AHSNKSAPTIMLFPEGTTTNGDYLLTFKTGAFLAGTPVLPVILKYPYERFSVAWDT--ISGARHILFLLCQFvnhleVIR 335
Cdd:PLN02833  231 HVQDPDRNPLLIFPEGTCVNNEYTVMFKKGAFELGCTVCPIAIKYNKIFVDAFWNSrkQSFTMHLLRLMTSW-----AVV 305

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2065889770 336 LPVYYPSQEEK---DDPKLYASNVRKLMATEGNL 366
Cdd:PLN02833  306 CDVWYLEPQTLrpgETPIEFAERVRDMIAKRAGL 339
 
Name Accession Description Interval E-value
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 140-377 1.75e-85

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 258.69  E-value: 1.75e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 140 RVLLFVFGFYWIHESCPDRDsdmdsnpkttsteinqkgeaateePERPGAIVSNHVSYLDILYHMSASFPSFVAKRSVGK 219
Cdd:cd07991     2 RVLLFAFGFYVIKVHGKPDP------------------------PEAPRIIVANHTSFIDPLILFSDLFPSIVAKKELGK 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 220 LPLVGLISKCLGCVYVQREakspDFKGVSGTVNERVREAHSnKSAPTIMLFPEGTTTNGDYLLTFKTGAFLAGTPVLPVI 299
Cdd:cd07991    58 LPFIGTILRALGCIFVDRS----EPKDRKKVVEEIKERATD-PNWPPILIFPEGTTTNGKALIMFKKGAFEPGVPVQPVA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 300 LKYPYeRFSVAWDTISGA---RHILFLLCQFVNHLEVIRLPVYYPSqEEKDDPKLYASNVRKLMATEGNLILSELGLSDK 376
Cdd:cd07991   133 IRYPN-KFVDAFWNSSGYsslMYLFRLLTQPANVLEVEFLPVYTPS-EEGEDPKEFANRVRLIMANKLGLPATDWTGEDK 210


                  .
gi 2065889770 377 R 377
Cdd:cd07991   211 R 211
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 190-302 1.95e-25

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 99.74  E-value: 1.95e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770  190 IVSNHVSYLDILYHMSASF-----PSFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDfkgvSGTVNERVREAHSNKSa 264
Cdd:smart00563   3 VVANHQSFLDPLVLSALLPrklgrVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKA----RAALREAVELLKEGEW- 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 2065889770  265 ptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVILKY 302
Cdd:smart00563  78 --LLIFPEGTRSRPGKLLPFKKGAARlaleAGVPIVPVAIRG 117
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 184-307 2.83e-25

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 101.19  E-value: 2.83e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 184 PERPGAIVSNHVSYLDILYHMSASFP--SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDFKGVSgTVNERVREAHSn 261
Cdd:cd07989    22 PKGPVIIVANHQSYLDPLVLGAALPRpiRFVAKKELFKIPFLGWLLRLLGAIPIDRGNGRSAREALR-EAIEALKEGES- 99

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2065889770 262 ksaptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVILKYPYERF 307
Cdd:cd07989   100 -----VVIFPEGTRSRDGELLPFKSGAFRlakeAGVPIVPVAISGTWGSL 144
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 184-363 7.92e-25

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 100.85  E-value: 7.92e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 184 PERPGAIVSNHVSYLDILYhMSASFP---SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDFKgvsgTVNERVREAHS 260
Cdd:COG0204    41 ADGPVLIVANHQSWLDILL-LLAALPrpvRFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAALR----ALRQAVEALKA 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 261 NKSaptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVILKYPYERFSvaWDTISGARHIlfllcqfvnhlEVIRL 336
Cdd:COG0204   116 GES---LVIFPEGTRSPDGRLLPFKTGAARlaleAGVPIVPVAIDGTERALP--KGFLPRPGKV-----------TVRIG 179

                         170       180
                  ....*....|....*....|....*..
gi 2065889770 337 PVYYPSQEEKDDPKLYASNVRKLMATE 363
Cdd:COG0204   180 PPIDPSDLEGEDRRELAERLRAAIEAL 206
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 184-301 3.31e-21

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 88.49  E-value: 3.31e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 184 PERPGAIVSNHVSYLD------ILYHMSASfPSFVAKRSVGKLPLVGLISKCLGCVYVQREakspDFKGVSGTVNERVRE 257
Cdd:pfam01553  12 RGGPAIVVANHQSYLDvlllslALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDRK----NRKDAAGTLEYLVEL 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2065889770 258 AHSNKSaptIMLFPEGTTTNGDYLLTFKTGAF----LAGTPVLPVILK 301
Cdd:pfam01553  87 LREGKL---VVIFPEGTRSREGELLPFKKGAFrlaiEAGVPIVPVAIS 131
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 184-300 1.72e-20

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 86.63  E-value: 1.72e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 184 PERPGAIV-SNHVSYLDILYhMSASFP---SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDfkgvsGTVNERVREAH 259
Cdd:TIGR00530  13 PAKSPVLVvANHQSNLDPLT-LSAAFPppiVFIAKKELKWIPFFGIMLWLTGAIFIDRENIRAI-----ATALKAAIEVL 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2065889770 260 SNKSAptIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVIL 300
Cdd:TIGR00530  87 KQGRS--IGVFPEGTRSRGRDILPFKKGAFHiaikAGVPILPVVL 129
PLN02833 PLN02833
glycerol acyltransferase family protein
 186-366 3.05e-11

glycerol acyltransferase family protein


Pssm-ID: 215447  Cd Length: 376  Bit Score: 64.41  E-value: 3.05e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 186 RPGAI-VSNHVSYLD--ILYHMSAsFpSFVAKRSVGklpLVGLISK----CLGCVYVQR-EAKSPDfkgvsgTVNERVRE 257
Cdd:PLN02833  162 RPKQVfVANHTSMIDfiVLEQMTP-F-AVIMQKHPG---WVGFLQNtileSVGCIWFNRtEAKDRE------VVAKKLRD 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 258 AHSNKSAPTIMLFPEGTTTNGDYLLTFKTGAFLAGTPVLPVILKYPYERFSVAWDT--ISGARHILFLLCQFvnhleVIR 335
Cdd:PLN02833  231 HVQDPDRNPLLIFPEGTCVNNEYTVMFKKGAFELGCTVCPIAIKYNKIFVDAFWNSrkQSFTMHLLRLMTSW-----AVV 305

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2065889770 336 LPVYYPSQEEK---DDPKLYASNVRKLMATEGNL 366
Cdd:PLN02833  306 CDVWYLEPQTLrpgETPIEFAERVRDMIAKRAGL 339
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
 184-300 8.79e-09

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 55.12  E-value: 8.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 184 PERPGAIVSNHVSYLDI--LYHMSASFpSFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDFKGVsgtvnERVREAHSN 261
Cdd:PLN02901   48 PDEPAVYVSNHQSFLDIytLFHLGRPF-KFISKTSIFLIPIIGWAMYMTGHIPLKRMDRRSQLECL-----KRCMELLKK 121

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2065889770 262 KSapTIMLFPEGTTTNGDYLLTFKTGAFL----AGTPVLPVIL 300
Cdd:PLN02901  122 GA--SVFFFPEGTRSKDGKLAAFKKGAFSvaakTGVPVVPITL 162
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
 184-361 3.17e-08

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 53.19  E-value: 3.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 184 PERPGAIVSNHVSYLD------ILYHMSASFPSFVAKRSvgKLPLVGLISKClGCVYVQReaksPDFKGVSGTVNErVRE 257
Cdd:cd06551    24 GGGPVLFVSNHSSWWDglilflLLERGLRRDVYGLMDEE--LLERYPFFTRL-GAFSVDR----DSPRSAAKSLKY-VAR 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 258 AHSNKSAPtIMLFPEGTTTNGDY-LLTFKTGAF----LAGTPVLPVILKYPYERFsvawdtisgarhilflLCQFVNHLE 332
Cdd:cd06551    96 LLSKPGSV-VWIFPEGTRTRRDKrPLQFKPGVAhlaeKAGVPIVPVALRYTFELF----------------EQFPEIFVR 158

                         170       180
                  ....*....|....*....|....*....
gi 2065889770 333 VIRLPVYYPSQEEKDDPKLYASNVRKLMA 361
Cdd:cd06551   159 IGPPIPYAETALGEELAAELANRLTRLLD 187
LPLAT_AAK14816-like cd07992
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 190-288 9.66e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.


Pssm-ID: 153254 [Multi-domain]  Cd Length: 203  Bit Score: 49.18  E-value: 9.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 190 IVSNHV-SYLDIL-YHMSASFP-SFVAKRSVGKLPLVGLISKCLGCVYVQREAKSPDfKGVSGTVNERVREAHSN--KSA 264
Cdd:cd07992    32 FLGNHPnALIDPLlLAATLRRPvRFLAKADLFKNPLIGWLLESFGAIPVYRPKDLAR-GGIGKISNAAVFDAVGEalKAG 110

                          90       100
                  ....*....|....*....|....
gi 2065889770 265 PTIMLFPEGTTTNGDYLLTFKTGA 288
Cdd:cd07992   111 GAIGIFPEGGSHDRPRLLPLKAGA 134
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 191-298 2.93e-06

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 48.09  E-value: 2.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 191 VSNHVSYLDILYHMSASFPSFV--AKRSVGKLPLVGLISKCLGCVYVQREAKSPDFKGVSGTVNervreaHSNKSAPTIM 268
Cdd:PRK15018   70 IANHQNNYDMVTASNIVQPPTVtvGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVN------HFKKRRISIW 143

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2065889770 269 LFPEGTTTNGDYLLTFKTGAF----LAGTPVLPV 298
Cdd:PRK15018  144 MFPEGTRSRGRGLLPFKTGAFhaaiAAGVPIIPV 177
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 189-303 4.65e-05

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 43.36  E-value: 4.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 189 AIVSNHVSYLDILYHMSASF-----PSFVAKRSVGKLPLvGLISKCLGCVYVQREAKSpdfkgvsGTVNERVREAHSNKS 263
Cdd:cd07988    24 VIGAPHTSNWDFVLGLLAAFalglkISFLGKHSLFKPPL-GPFMRWLGGIPVDRSRAG-------GLVEQVVEEFRRREE 95

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2065889770 264 ApTIMLFPEGTTTNGDYlltFKTG----AFLAGTPVLPVILKYP 303
Cdd:cd07988    96 F-VLAIAPEGTRSKVDK---WKTGfyhiARGAGVPILLVYLDYK 135
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
 190-274 5.06e-05

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 43.77  E-value: 5.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065889770 190 IVSNHVSYLDILYHMSASFPS-------FVAKRSVGKLPLVGLISKCLGCVYVQReakspdfkgvSGTVNERVREAHSNK 262
Cdd:cd07990    28 IISNHRSEVDWLVLWMLADRFgrlgrlkIVLKDSLKYPPLGGWGWQLGEFIFLKR----------KWEKDEKTIKRQLKR 97

                          90
                  ....*....|....*..
gi 2065889770 263 SAPT-----IMLFPEGT 274
Cdd:cd07990    98 LKDSpepfwLLIFPEGT 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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