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Conserved domains on  [gi|2054988920|ref|WP_216264666|]
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MULTISPECIES: hypothetical protein [Enterobacteriaceae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cro super family cl46781
Cro; Members of this family are involved in the repression of transcription by binding as a ...
 48-84 5.07e-04

Cro; Members of this family are involved in the repression of transcription by binding as a homodimer to palindromic DNA operator sites in phage lambda: they repress genes expressed in early phage development and are necessary for the late stage of lytic growth. These proteins have a secondary structure consisting of three alpha-helices and three beta-sheets, and dimerize through interactions between the two antiparallel beta-strands.


The actual alignment was detected with superfamily member COG4197:

Pssm-ID: 481121  Cd Length: 68  Bit Score: 36.04  E-value: 5.07e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2054988920  48 MELVIEAYGGIAKTAKELGVSIQVVQQWIK-RGMISAD 84
Cdd:COG4197     1 LEKAIEALGSQSALARALGVSQQAVSQWLNgKRRVPAE 38
 
Name Accession Description Interval E-value
YdaS COG4197
DNA-binding transcriptional regulator YdaS, prophage-encoded, Cro superfamily [Transcription];
48-84 5.07e-04

DNA-binding transcriptional regulator YdaS, prophage-encoded, Cro superfamily [Transcription];


Pssm-ID: 443351  Cd Length: 68  Bit Score: 36.04  E-value: 5.07e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2054988920  48 MELVIEAYGGIAKTAKELGVSIQVVQQWIK-RGMISAD 84
Cdd:COG4197     1 LEKAIEALGSQSALARALGVSQQAVSQWLNgKRRVPAE 38
 
Name Accession Description Interval E-value
YdaS COG4197
DNA-binding transcriptional regulator YdaS, prophage-encoded, Cro superfamily [Transcription];
48-84 5.07e-04

DNA-binding transcriptional regulator YdaS, prophage-encoded, Cro superfamily [Transcription];


Pssm-ID: 443351  Cd Length: 68  Bit Score: 36.04  E-value: 5.07e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2054988920  48 MELVIEAYGGIAKTAKELGVSIQVVQQWIK-RGMISAD 84
Cdd:COG4197     1 LEKAIEALGSQSALARALGVSQQAVSQWLNgKRRVPAE 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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