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Conserved domains on  [gi|2052112515|ref|XP_041873433|]
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interleukin-22 receptor subunit alpha-2 isoform X4 [Corvus kubaryi]

Protein Classification

Tissue_fac and Interfer-bind domain-containing protein( domain architecture ID 10471435)

Tissue_fac and Interfer-bind domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tissue_fac pfam01108
Tissue factor; This family is found in metazoa, and is very similar to the fibronectin type ...
 16-100 9.78e-27

Tissue factor; This family is found in metazoa, and is very similar to the fibronectin type III domain. The family is found in cytokine receptors, interleukin and interferon receptors and coagulation factor III proteins. It occurs multiple times, as does fn3, family pfam00041.


:

Pssm-ID: 460067  Cd Length: 107  Bit Score: 98.61  E-value: 9.78e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052112515  16 KPQKVEFHSLNFNTTLHWQPGWAREaRDALYFVQYKVYGQSTWQNKDDCWGIPSRVCDLTHETSDIQEPYYGRVRATLAG 95
Cdd:pfam01108  24 APQNVTFQSTNFKNILTWEPGPNSP-PDVVYTVQYKIYGSGDWKNVPNCTNITRTECDLTDETSDLTETYYARVRAVSGG 102


                  ....*
gi 2052112515  96 VYSSW 100
Cdd:pfam01108 103 GTSSW 107
Interfer-bind pfam09294
Interferon-alpha/beta receptor, fibronectin type III; Members of this family adopt a secondary ...
 112-216 1.92e-19

Interferon-alpha/beta receptor, fibronectin type III; Members of this family adopt a secondary structure consisting of seven beta-strands arranged in an immunoglobulin-like beta-sandwich, in a Greek-key topology. They are required for binding to interferon-alpha.


:

Pssm-ID: 462746  Cd Length: 103  Bit Score: 79.69  E-value: 1.92e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052112515 112 TMVGPPMVTVVHSNKSIIVKLQAPQspykRKRGSKITMTNYY-DLLYQVFIINNllDEQHRVLVYEGKDKVIKIQDLRPG 190
Cdd:pfam09294   1 TIIGPPEVELEVEGGSLNVTVKDPE----TREGKNLSLRDLYgSLQYRVSYWKN--SSNGEKKNTTSTNSFVVLSDLEPG 74

                          90       100
                  ....*....|....*....|....*.
gi 2052112515 191 VSYCIVAKTYVPMLDRSSAYSSRQCT 216
Cdd:pfam09294  75 TTYCVSVQAFSPLDNKSSQRSPPQCI 100
 
Name Accession Description Interval E-value
Tissue_fac pfam01108
Tissue factor; This family is found in metazoa, and is very similar to the fibronectin type ...
 16-100 9.78e-27

Tissue factor; This family is found in metazoa, and is very similar to the fibronectin type III domain. The family is found in cytokine receptors, interleukin and interferon receptors and coagulation factor III proteins. It occurs multiple times, as does fn3, family pfam00041.


Pssm-ID: 460067  Cd Length: 107  Bit Score: 98.61  E-value: 9.78e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052112515  16 KPQKVEFHSLNFNTTLHWQPGWAREaRDALYFVQYKVYGQSTWQNKDDCWGIPSRVCDLTHETSDIQEPYYGRVRATLAG 95
Cdd:pfam01108  24 APQNVTFQSTNFKNILTWEPGPNSP-PDVVYTVQYKIYGSGDWKNVPNCTNITRTECDLTDETSDLTETYYARVRAVSGG 102


                  ....*
gi 2052112515  96 VYSSW 100
Cdd:pfam01108 103 GTSSW 107
Interfer-bind pfam09294
Interferon-alpha/beta receptor, fibronectin type III; Members of this family adopt a secondary ...
 112-216 1.92e-19

Interferon-alpha/beta receptor, fibronectin type III; Members of this family adopt a secondary structure consisting of seven beta-strands arranged in an immunoglobulin-like beta-sandwich, in a Greek-key topology. They are required for binding to interferon-alpha.


Pssm-ID: 462746  Cd Length: 103  Bit Score: 79.69  E-value: 1.92e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052112515 112 TMVGPPMVTVVHSNKSIIVKLQAPQspykRKRGSKITMTNYY-DLLYQVFIINNllDEQHRVLVYEGKDKVIKIQDLRPG 190
Cdd:pfam09294   1 TIIGPPEVELEVEGGSLNVTVKDPE----TREGKNLSLRDLYgSLQYRVSYWKN--SSNGEKKNTTSTNSFVVLSDLEPG 74

                          90       100
                  ....*....|....*....|....*.
gi 2052112515 191 VSYCIVAKTYVPMLDRSSAYSSRQCT 216
Cdd:pfam09294  75 TTYCVSVQAFSPLDNKSSQRSPPQCI 100
 
Name Accession Description Interval E-value
Tissue_fac pfam01108
Tissue factor; This family is found in metazoa, and is very similar to the fibronectin type ...
 16-100 9.78e-27

Tissue factor; This family is found in metazoa, and is very similar to the fibronectin type III domain. The family is found in cytokine receptors, interleukin and interferon receptors and coagulation factor III proteins. It occurs multiple times, as does fn3, family pfam00041.


Pssm-ID: 460067  Cd Length: 107  Bit Score: 98.61  E-value: 9.78e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052112515  16 KPQKVEFHSLNFNTTLHWQPGWAREaRDALYFVQYKVYGQSTWQNKDDCWGIPSRVCDLTHETSDIQEPYYGRVRATLAG 95
Cdd:pfam01108  24 APQNVTFQSTNFKNILTWEPGPNSP-PDVVYTVQYKIYGSGDWKNVPNCTNITRTECDLTDETSDLTETYYARVRAVSGG 102


                  ....*
gi 2052112515  96 VYSSW 100
Cdd:pfam01108 103 GTSSW 107
Interfer-bind pfam09294
Interferon-alpha/beta receptor, fibronectin type III; Members of this family adopt a secondary ...
 112-216 1.92e-19

Interferon-alpha/beta receptor, fibronectin type III; Members of this family adopt a secondary structure consisting of seven beta-strands arranged in an immunoglobulin-like beta-sandwich, in a Greek-key topology. They are required for binding to interferon-alpha.


Pssm-ID: 462746  Cd Length: 103  Bit Score: 79.69  E-value: 1.92e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2052112515 112 TMVGPPMVTVVHSNKSIIVKLQAPQspykRKRGSKITMTNYY-DLLYQVFIINNllDEQHRVLVYEGKDKVIKIQDLRPG 190
Cdd:pfam09294   1 TIIGPPEVELEVEGGSLNVTVKDPE----TREGKNLSLRDLYgSLQYRVSYWKN--SSNGEKKNTTSTNSFVVLSDLEPG 74

                          90       100
                  ....*....|....*....|....*.
gi 2052112515 191 VSYCIVAKTYVPMLDRSSAYSSRQCT 216
Cdd:pfam09294  75 TTYCVSVQAFSPLDNKSSQRSPPQCI 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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