Chain W, General transcription factor IIE subunit 1
transcription initiation factor IIE subunit alpha family protein( domain architecture ID 12214403)
transcription initiation factor IIE (TFIIE) subunit alpha family protein may be involved in melting promoter DNA at the transcription initiation site.
List of domain hits
Name | Accession | Description | Interval | E-value | |||
TFIIE | smart00531 | Transcription initiation factor IIE; |
28-175 | 3.15e-64 | |||
Transcription initiation factor IIE; : Pssm-ID: 128804 [Multi-domain] Cd Length: 147 Bit Score: 203.37 E-value: 3.15e-64
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TFIIE-A_C | pfam11521 | C-terminal general transcription factor TFIIE alpha; TFIIE is compiled of two subunits, alpha ... |
394-439 | 2.29e-26 | |||
C-terminal general transcription factor TFIIE alpha; TFIIE is compiled of two subunits, alpha and beta. This family of proteins are the C terminal domain of the alpha subunit of the protein which is the largest subunit and contains several functional domains which are important for basal transcription and cell growth. The C terminal end of the protein binds directly to the amino-terminal PH domain of p62/Tfb1 (of IIH) which is involved in the recruitment of the general transcription factor IIH to the transcription preinitiation complex. P53 competes for the same binding site as TFIIE alpha which shows their structural similarity. Like p53, TFIIE alpha 336-439 can activate transcription in vivo. : Pssm-ID: 463287 Cd Length: 85 Bit Score: 101.64 E-value: 2.29e-26
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Name | Accession | Description | Interval | E-value | |||
TFIIE | smart00531 | Transcription initiation factor IIE; |
28-175 | 3.15e-64 | |||
Transcription initiation factor IIE; Pssm-ID: 128804 [Multi-domain] Cd Length: 147 Bit Score: 203.37 E-value: 3.15e-64
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TFIIE_alpha | pfam02002 | TFIIE alpha subunit; The general transcription factor TFIIE has an essential role in ... |
16-123 | 5.08e-44 | |||
TFIIE alpha subunit; The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits TFIIE-alpha and TFIIE-beta and joins the pre-initiation complex after RNA polymerase II and TFIIF. This family consists of the conserved amino terminal region of eukaryotic TFIIE-alpha and proteins from archaebacteria that are presumed to be TFIIE-alpha subunits also Swiss:O29501. Pssm-ID: 280224 Cd Length: 105 Bit Score: 149.47 E-value: 5.08e-44
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TFIIE-A_C | pfam11521 | C-terminal general transcription factor TFIIE alpha; TFIIE is compiled of two subunits, alpha ... |
394-439 | 2.29e-26 | |||
C-terminal general transcription factor TFIIE alpha; TFIIE is compiled of two subunits, alpha and beta. This family of proteins are the C terminal domain of the alpha subunit of the protein which is the largest subunit and contains several functional domains which are important for basal transcription and cell growth. The C terminal end of the protein binds directly to the amino-terminal PH domain of p62/Tfb1 (of IIH) which is involved in the recruitment of the general transcription factor IIH to the transcription preinitiation complex. P53 competes for the same binding site as TFIIE alpha which shows their structural similarity. Like p53, TFIIE alpha 336-439 can activate transcription in vivo. Pssm-ID: 463287 Cd Length: 85 Bit Score: 101.64 E-value: 2.29e-26
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Name | Accession | Description | Interval | E-value | |||
TFIIE | smart00531 | Transcription initiation factor IIE; |
28-175 | 3.15e-64 | |||
Transcription initiation factor IIE; Pssm-ID: 128804 [Multi-domain] Cd Length: 147 Bit Score: 203.37 E-value: 3.15e-64
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TFIIE_alpha | pfam02002 | TFIIE alpha subunit; The general transcription factor TFIIE has an essential role in ... |
16-123 | 5.08e-44 | |||
TFIIE alpha subunit; The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits TFIIE-alpha and TFIIE-beta and joins the pre-initiation complex after RNA polymerase II and TFIIF. This family consists of the conserved amino terminal region of eukaryotic TFIIE-alpha and proteins from archaebacteria that are presumed to be TFIIE-alpha subunits also Swiss:O29501. Pssm-ID: 280224 Cd Length: 105 Bit Score: 149.47 E-value: 5.08e-44
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TFIIE-A_C | pfam11521 | C-terminal general transcription factor TFIIE alpha; TFIIE is compiled of two subunits, alpha ... |
394-439 | 2.29e-26 | |||
C-terminal general transcription factor TFIIE alpha; TFIIE is compiled of two subunits, alpha and beta. This family of proteins are the C terminal domain of the alpha subunit of the protein which is the largest subunit and contains several functional domains which are important for basal transcription and cell growth. The C terminal end of the protein binds directly to the amino-terminal PH domain of p62/Tfb1 (of IIH) which is involved in the recruitment of the general transcription factor IIH to the transcription preinitiation complex. P53 competes for the same binding site as TFIIE alpha which shows their structural similarity. Like p53, TFIIE alpha 336-439 can activate transcription in vivo. Pssm-ID: 463287 Cd Length: 85 Bit Score: 101.64 E-value: 2.29e-26
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TF_Zn_Ribbon | pfam08271 | TFIIB zinc-binding; The transcription factor TFIIB contains a zinc-binding motif near the ... |
127-175 | 1.39e-06 | |||
TFIIB zinc-binding; The transcription factor TFIIB contains a zinc-binding motif near the N-terminus. This domain is involved in the interaction with RNA pol II and TFIIF and plays a crucial role in selecting the transcription initiation site. The domain adopts a zinc ribbon like structure. Pssm-ID: 400527 [Multi-domain] Cd Length: 43 Bit Score: 44.61 E-value: 1.39e-06
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Blast search parameters | ||||
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