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Conserved domains on  [gi|2033627795|gb|QUV72172|]
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N-acetylglucosaminyltransferase, partial [Paraburkholderia sp.]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
nodulat_NodC super family cl37405
chitooligosaccharide synthase NodC; Members of this family are NodC, an ...
 1-182 8.78e-101

chitooligosaccharide synthase NodC; Members of this family are NodC, an N-acetylglucosaminyltransferase involved in the production of nodulation factors through which rhizobia establish symbioses with leguminous plants.


The actual alignment was detected with superfamily member TIGR04242:

Pssm-ID: 275076 [Multi-domain]  Cd Length: 395  Bit Score: 295.88  E-value: 8.78e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795   1 AVMCCCGPCAIYRRTALLLLLDLYETQTFRGKRSDFGEDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRWA 80
Cdd:TIGR04242 202 AVMCCCGPCAMYRRSALLSLLDQYETQLFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDKLGPYLRQQLRWA 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795  81 RSTYRDTLLALQLLPRLDSYLTLDVLAQNMGSLLLAISMLAGFLQMVLTATAPWDACFVIASMPIVRCSVAAIRTRQIRF 160
Cdd:TIGR04242 282 RSTFRDTLLALRLLPGLDRYLTLDVIGQNLGPLLLALSVLTGLAQLALTATVPWWTILVIAAMTIIRCCVAALRARQLRF 361

                         170       180
                  ....*....|....*....|..
gi 2033627795 161 LGFSAHTLINLSLLLPVKAYAL 182
Cdd:TIGR04242 362 LGFSLHTFINIFLLLPLKAYAL 383
 
Name Accession Description Interval E-value
nodulat_NodC TIGR04242
chitooligosaccharide synthase NodC; Members of this family are NodC, an ...
 1-182 8.78e-101

chitooligosaccharide synthase NodC; Members of this family are NodC, an N-acetylglucosaminyltransferase involved in the production of nodulation factors through which rhizobia establish symbioses with leguminous plants.


Pssm-ID: 275076 [Multi-domain]  Cd Length: 395  Bit Score: 295.88  E-value: 8.78e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795   1 AVMCCCGPCAIYRRTALLLLLDLYETQTFRGKRSDFGEDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRWA 80
Cdd:TIGR04242 202 AVMCCCGPCAMYRRSALLSLLDQYETQLFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDKLGPYLRQQLRWA 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795  81 RSTYRDTLLALQLLPRLDSYLTLDVLAQNMGSLLLAISMLAGFLQMVLTATAPWDACFVIASMPIVRCSVAAIRTRQIRF 160
Cdd:TIGR04242 282 RSTFRDTLLALRLLPGLDRYLTLDVIGQNLGPLLLALSVLTGLAQLALTATVPWWTILVIAAMTIIRCCVAALRARQLRF 361

                         170       180
                  ....*....|....*....|..
gi 2033627795 161 LGFSAHTLINLSLLLPVKAYAL 182
Cdd:TIGR04242 362 LGFSLHTFINIFLLLPLKAYAL 383
GT2_HAS cd06434
Hyaluronan synthases catalyze polymerization of hyaluronan; Hyaluronan synthases (HASs) are ...
 2-85 5.24e-14

Hyaluronan synthases catalyze polymerization of hyaluronan; Hyaluronan synthases (HASs) are bi-functional glycosyltransferases that catalyze polymerization of hyaluronan. HASs transfer both GlcUA and GlcNAc in beta-(1,3) and beta-(1,4) linkages, respectively to the hyaluronan chain using UDP-GlcNAc and UDP-GlcUA as substrates. HA is made as a free glycan, not attached to a protein or lipid. HASs do not need a primer for HA synthesis; they initiate HA biosynthesis de novo with only UDP-GlcNAc, UDP-GlcUA, and Mg2+. Hyaluronan (HA) is a linear heteropolysaccharide composed of (1-3)-linked beta-D-GlcUA-beta-D-GlcNAc disaccharide repeats. It can be found in vertebrates and a few microbes and is typically on the cell surface or in the extracellular space, but is also found inside mammalian cells. Hyaluronan has several physiochemical and biological functions such as space filling, lubrication, and providing a hydrated matrix through which cells can migrate.


Pssm-ID: 133056 [Multi-domain]  Cd Length: 235  Bit Score: 67.28  E-value: 5.24e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795   2 VMCCCGPCAIYRRTALLLLLDLYE--TQTFRGKRSDFGEDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRW 79
Cdd:cd06434   149 VPCLSGRTAAYRTEILKDFLFLEEftNETFMGRRLNAGDDRFLTRYVLSHGYKTVYQYTSEAYTETPENYKKFLKQQLRW 228


                  ....*.
gi 2033627795  80 ARSTYR 85
Cdd:cd06434   229 SRSNWR 234
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 5-178 2.28e-09

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 55.13  E-value: 2.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795   5 CCGPCAIYRRTALLllldlyETQTFRgkRSDFGEDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRWARSTY 84
Cdd:COG1215   143 ASGANLAFRREALE------EVGGFD--EDTLGEDLDLSLRLLRAGYRIVYVPDAVVYEEAPETLRALFRQRRRWARGGL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795  85 RdtllalqllprldSYLTLDVLAQNMGSLLLAISMLAGFLQMVLTATAPWDACFVIASMPIVRCSVAAIRTRQIRFLGFS 164
Cdd:COG1215   215 Q-------------LLLKHRPLLRPRRLLLFLLLLLLPLLLLLLLLALLALLLLLLPALLLALLLALRRRRLLLPLLHLL 281

                         170
                  ....*....|....
gi 2033627795 165 AHTLINLSLLLPVK 178
Cdd:COG1215   282 YGLLLLLAALRGKK 295
bcsA PRK11498
cellulose synthase catalytic subunit; Provisional
 6-81 6.15e-06

cellulose synthase catalytic subunit; Provisional


Pssm-ID: 236918 [Multi-domain]  Cd Length: 852  Bit Score: 45.40  E-value: 6.15e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2033627795   6 CGPCAIYRRTALLLL-LDLYETQTfrgkrsdfgEDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRWAR 81
Cdd:PRK11498  419 CGSCAVIRRKPLDEIgGIAVETVT---------EDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWAR 486
Chitin_synth_2 pfam03142
Chitin synthase; Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They ...
 37-83 1.02e-04

Chitin synthase; Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They catalyze chitin synthesis as follows: UDP-N-acetyl-D-glucosamine + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N) <=> UDP + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N+1).


Pssm-ID: 367353 [Multi-domain]  Cd Length: 527  Bit Score: 41.67  E-value: 1.02e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2033627795  37 GEDRHLPLLLLAA--GYGTEYVRGAVAATVVPDSLQPYLRQQLRWARST 83
Cdd:pfam03142 326 GEDRYLTTLMLKTfpKRKTVFVPQAVCKTIAPDTFKVLLSQRRRWINST 374
 
Name Accession Description Interval E-value
nodulat_NodC TIGR04242
chitooligosaccharide synthase NodC; Members of this family are NodC, an ...
 1-182 8.78e-101

chitooligosaccharide synthase NodC; Members of this family are NodC, an N-acetylglucosaminyltransferase involved in the production of nodulation factors through which rhizobia establish symbioses with leguminous plants.


Pssm-ID: 275076 [Multi-domain]  Cd Length: 395  Bit Score: 295.88  E-value: 8.78e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795   1 AVMCCCGPCAIYRRTALLLLLDLYETQTFRGKRSDFGEDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRWA 80
Cdd:TIGR04242 202 AVMCCCGPCAMYRRSALLSLLDQYETQLFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDKLGPYLRQQLRWA 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795  81 RSTYRDTLLALQLLPRLDSYLTLDVLAQNMGSLLLAISMLAGFLQMVLTATAPWDACFVIASMPIVRCSVAAIRTRQIRF 160
Cdd:TIGR04242 282 RSTFRDTLLALRLLPGLDRYLTLDVIGQNLGPLLLALSVLTGLAQLALTATVPWWTILVIAAMTIIRCCVAALRARQLRF 361

                         170       180
                  ....*....|....*....|..
gi 2033627795 161 LGFSAHTLINLSLLLPVKAYAL 182
Cdd:TIGR04242 362 LGFSLHTFINIFLLLPLKAYAL 383
GT2_HAS cd06434
Hyaluronan synthases catalyze polymerization of hyaluronan; Hyaluronan synthases (HASs) are ...
 2-85 5.24e-14

Hyaluronan synthases catalyze polymerization of hyaluronan; Hyaluronan synthases (HASs) are bi-functional glycosyltransferases that catalyze polymerization of hyaluronan. HASs transfer both GlcUA and GlcNAc in beta-(1,3) and beta-(1,4) linkages, respectively to the hyaluronan chain using UDP-GlcNAc and UDP-GlcUA as substrates. HA is made as a free glycan, not attached to a protein or lipid. HASs do not need a primer for HA synthesis; they initiate HA biosynthesis de novo with only UDP-GlcNAc, UDP-GlcUA, and Mg2+. Hyaluronan (HA) is a linear heteropolysaccharide composed of (1-3)-linked beta-D-GlcUA-beta-D-GlcNAc disaccharide repeats. It can be found in vertebrates and a few microbes and is typically on the cell surface or in the extracellular space, but is also found inside mammalian cells. Hyaluronan has several physiochemical and biological functions such as space filling, lubrication, and providing a hydrated matrix through which cells can migrate.


Pssm-ID: 133056 [Multi-domain]  Cd Length: 235  Bit Score: 67.28  E-value: 5.24e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795   2 VMCCCGPCAIYRRTALLLLLDLYE--TQTFRGKRSDFGEDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRW 79
Cdd:cd06434   149 VPCLSGRTAAYRTEILKDFLFLEEftNETFMGRRLNAGDDRFLTRYVLSHGYKTVYQYTSEAYTETPENYKKFLKQQLRW 228


                  ....*.
gi 2033627795  80 ARSTYR 85
Cdd:cd06434   229 SRSNWR 234
CESA_CelA_like cd06421
CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Family of ...
 5-85 3.79e-11

CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.


Pssm-ID: 133043 [Multi-domain]  Cd Length: 234  Bit Score: 59.51  E-value: 3.79e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795   5 CCGPCAIYRRTALLLLLDLYETqtfrgkrsDFGEDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRWARSTY 84
Cdd:cd06421   160 CCGSGAVVRREALDEIGGFPTD--------SVTEDLATSLRLHAKGWRSVYVPEPLAAGLAPETLAAYIKQRLRWARGML 231


                  .
gi 2033627795  85 R 85
Cdd:cd06421   232 Q 232
Chitin_synth_C cd04190
C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate ...
 35-84 2.16e-09

C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin; Chitin synthase, also called UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase, catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of GlcNAc residues formed by covalent beta-1,4 linkages. Chitin is an important component of the cell wall of fungi and bacteria and it is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. Studies with fungi have revealed that most of them contain more than one chitin synthase gene. At least five subclasses of chitin synthases have been identified.


Pssm-ID: 133033 [Multi-domain]  Cd Length: 244  Bit Score: 55.01  E-value: 2.16e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2033627795  35 DFGEDRHLPLLLLAAGYGTE--YVRGAVAATVVPDSLQPYLRQQLRWARSTY 84
Cdd:cd04190   191 DLGEDRILCTLLLKAGPKRKylYVPGAVAETDVPETFVELLSQRRRWINSTI 242
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 5-178 2.28e-09

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 55.13  E-value: 2.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795   5 CCGPCAIYRRTALLllldlyETQTFRgkRSDFGEDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRWARSTY 84
Cdd:COG1215   143 ASGANLAFRREALE------EVGGFD--EDTLGEDLDLSLRLLRAGYRIVYVPDAVVYEEAPETLRALFRQRRRWARGGL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2033627795  85 RdtllalqllprldSYLTLDVLAQNMGSLLLAISMLAGFLQMVLTATAPWDACFVIASMPIVRCSVAAIRTRQIRFLGFS 164
Cdd:COG1215   215 Q-------------LLLKHRPLLRPRRLLLFLLLLLLPLLLLLLLLALLALLLLLLPALLLALLLALRRRRLLLPLLHLL 281

                         170
                  ....*....|....
gi 2033627795 165 AHTLINLSLLLPVK 178
Cdd:COG1215   282 YGLLLLLAALRGKK 295
bcsA PRK11498
cellulose synthase catalytic subunit; Provisional
 6-81 6.15e-06

cellulose synthase catalytic subunit; Provisional


Pssm-ID: 236918 [Multi-domain]  Cd Length: 852  Bit Score: 45.40  E-value: 6.15e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2033627795   6 CGPCAIYRRTALLLL-LDLYETQTfrgkrsdfgEDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRWAR 81
Cdd:PRK11498  419 CGSCAVIRRKPLDEIgGIAVETVT---------EDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWAR 486
Chitin_synth_2 pfam03142
Chitin synthase; Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They ...
 37-83 1.02e-04

Chitin synthase; Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They catalyze chitin synthesis as follows: UDP-N-acetyl-D-glucosamine + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N) <=> UDP + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N+1).


Pssm-ID: 367353 [Multi-domain]  Cd Length: 527  Bit Score: 41.67  E-value: 1.02e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2033627795  37 GEDRHLPLLLLAA--GYGTEYVRGAVAATVVPDSLQPYLRQQLRWARST 83
Cdd:pfam03142 326 GEDRYLTTLMLKTfpKRKTVFVPQAVCKTIAPDTFKVLLSQRRRWINST 374
Glyco_trans_2_3 pfam13632
Glycosyl transferase family group 2; Members of this family of prokaryotic proteins include ...
 37-81 1.81e-03

Glycosyl transferase family group 2; Members of this family of prokaryotic proteins include putative glucosyltransferases, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433365 [Multi-domain]  Cd Length: 192  Bit Score: 37.32  E-value: 1.81e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2033627795  37 GEDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRWAR 81
Cdd:pfam13632  96 SEDFDFGLRLQRAGYRVRFAPYSAVYEKSPLTFRDFLRQRRRWAY 140
CESA_NdvC_like cd06435
NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase; ...
 38-80 2.06e-03

NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase; NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. Bradyrhizobium japonicum synthesizes periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans during growth under hypoosmotic conditions. Two genes (ndvB, ndvC) are involved in the beta-(1, 3), beta-(1,6)-glucan synthesis. The ndvC mutant strain resulted in synthesis of altered cyclic beta-glucans composed almost entirely of beta-(1, 3)-glycosyl linkages. The periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans function for osmoregulation. The ndvC mutation also affects the ability of the bacteria to establish a successful symbiotic interaction with host plant. Thus, the beta-glucans may function as suppressors of a host defense response.


Pssm-ID: 133057 [Multi-domain]  Cd Length: 236  Bit Score: 37.38  E-value: 2.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2033627795  38 EDRHLPLLLLAAGYGTEYVRGAVAATVVPDSLQPYLRQQLRWA 80
Cdd:cd06435   183 EDSELGLRMHEAGYIGVYVAQSYGHGLIPDTFEAFKKQRFRWA 225
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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