|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
15-583 |
0e+00 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 1125.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 15 AMPHEEPELTDGFHLVIDALKLNGIETIYNVPGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVS 94
Cdd:PRK09259 1 TAMSDQLQLTDGFHLVIDALKLNGIDTIYGVVGIPITDLARLAQAEGIRYIGFRHEQSAGNAAAAAGFLTQKPGVCLTVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 95 APGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGR 174
Cdd:PRK09259 81 APGFLNGLTALANATTNCFPMIMISGSSEREIVDLQQGDYEELDQLNAAKPFCKAAFRVNRAEDIGIGVARAIRTAVSGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 175 PGGVYLDLPAKLFSQVIDADLGARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEES 254
Cdd:PRK09259 161 PGGVYLDLPAKVLAQTMDADEALTSLVKVVDPAPAQLPAPEAVDRALDLLKKAKRPLIILGKGAAYAQADEQIREFVEKT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 255 GIPYVPMSMAKGLLPDTHPLSAGAARSTALKDSDVVLLVGARLNWLLSHGKGKTWGepGSKRFIQIDIEPREMDSNVEIV 334
Cdd:PRK09259 241 GIPFLPMSMAKGLLPDTHPQSAAAARSLALANADVVLLVGARLNWLLSHGKGKTWG--ADKKFIQIDIEPQEIDSNRPIA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 335 APVVGDIGSCVEALLDGIRKDWKGAPSNWLETLRGKREANIAKMAPKLMKNSSPMCFHSALGALRTVIKERPDAILVNEG 414
Cdd:PRK09259 319 APVVGDIGSVMQALLAGLKQNTFKAPAEWLDALAERKEKNAAKMAEKLSTDTQPMNFYNALGAIRDVLKENPDIYLVNEG 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 415 ANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMGFAVAAAVETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIFNNN 494
Cdd:PRK09259 399 ANTLDLARNIIDMYKPRHRLDCGTWGVMGIGMGYAIAAAVETGKPVVAIEGDSAFGFSGMEVETICRYNLPVTVVIFNNG 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 495 GIYRGTDTDPTG-RDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEIDPAAGSESGNIGS 573
Cdd:PRK09259 479 GIYRGDDVNLSGaGDPSPTVLVHHARYDKMMEAFGGVGYNVTTPDELRHALTEAIASGKPTLINVVIDPAAGTESGHITN 558
|
570
....*....|
gi 2030910552 574 LNPQSTLKKK 583
Cdd:PRK09259 559 LNPKSVAGKK 568
|
|
| oxalate_oxc |
TIGR03254 |
oxalyl-CoA decarboxylase; In a number of bacteria, including Oxalobacter formigenes from the ... |
22-577 |
0e+00 |
|
oxalyl-CoA decarboxylase; In a number of bacteria, including Oxalobacter formigenes from the human gut, a two-gene operon of oxc (oxalyl-CoA decarboxylase) and frc (formyl-CoA transferase) encodes a system for degrading and therefore detoxifying oxalate. Members of this family are the thiamine pyrophosphate (TPP)-containing enzyme oxalyl-CoA decarboxylase. [Cellular processes, Detoxification]
Pssm-ID: 132298 [Multi-domain] Cd Length: 554 Bit Score: 976.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 22 ELTDGFHLVIDALKLNGIETIYNVPGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNG 101
Cdd:TIGR03254 1 ALTDGFHLVIDALKLNGINTIYGVVGIPVTDLARLAQAKGMRYIGFRHEQSAGYAAAAAGFLTQKPGVCLTVSAPGFLNG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 102 LTALANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLD 181
Cdd:TIGR03254 81 LTALANATTNCFPMIMISGSSERHIVDLQQGDYEEMDQLAAAKPFAKAAYRVLRAEDIGIGIARAIRTAVSGRPGGVYLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 182 LPAKLFSQVIDADLGARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVPM 261
Cdd:TIGR03254 161 LPAAVLGQTMEAEKAKKTLVKVVDPAPKQLPSPDSVDRAVELLKDAKRPLILLGKGAAYAQADEEIREFVEKTGIPFLPM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 262 SMAKGLLPDTHPLSAGAARSTALKDSDVVLLVGARLNWLLSHGKGKTWGEPgsKRFIQIDIEPREMDSNVEIVAPVVGDI 341
Cdd:TIGR03254 241 SMAKGLLPDTHPQSAAAARSFALAEADVVMLVGARLNWLLSHGKGKLWGED--AKFIQVDIEPTEMDSNRPIAAPVVGDI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 342 GSCVEALLDGIRKDWKGAPSNWLETLRGKREANIAKMAPKLMKNSSPMCFHSALGALRTVIKERPDAILVNEGANTLDLA 421
Cdd:TIGR03254 319 GSVVQALLSAAKNGGVKPPADWRNAIKTKSEKNVAKMAERLSASESPMNYHGALEAIRDVLKDNPDIYLVNEGANTLDLA 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 422 RGIIDMYQPRKRLDVGTWGVMGIGMGFAVAAAVETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIFNNNGIYRGTD 501
Cdd:TIGR03254 399 RNVIDMYKPRHRLDVGTWGVMGIGMGYAIAAAVETGKPVVALEGDSAFGFSGMEVETICRYNLPVCVVIFNNGGIYRGDD 478
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2030910552 502 TDPTGRDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEIDPAAGSESGNIGSLNPQ 577
Cdd:TIGR03254 479 VNVVGADPAPTVLVHGARYDKMMKAFGGVGYNVTTPDELKAALNEALASGKPTLINAVIDPSAGTESGHIGNLNPK 554
|
|
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
26-574 |
1.41e-138 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 413.40 E-value: 1.41e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 26 GFHLVIDALKLNGIETIYNVPGIPITDLGR-LAQAEGLRVISFRHEQNAGnaaaiagF-------LTKKPGICLTVSAPG 97
Cdd:COG0028 5 GADALVEALEAEGVETVFGVPGGAILPLYDaLRRQSGIRHILVRHEQGAA-------FmadgyarATGKPGVCLVTSGPG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 98 FLNGLTALANATTNCFPMILISGSSEREivDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGG 177
Cdd:COG0028 78 ATNLVTGLADAYMDSVPVLAITGQVPTS--LIGRGAFQEVDQVGLFRPITKWSYLVTDPEDLPEVLRRAFRIATSGRPGP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 178 VYLDLPAKLFSQVIDADLGARSLVKVidaAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIP 257
Cdd:COG0028 156 VVLDIPKDVQAAEAEEEPAPPELRGY---RPRPAPDPEAIEEAAELLAAAKRPVILAGGGARRAGAAEELRALAERLGAP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 258 YVPMSMAKGLLPDTHPLSAG-------AARSTALKDSDVVLLVGARLNWLLShGKGKTWgePGSKRFIQIDIEPREMDSN 330
Cdd:COG0028 233 VVTTLMGKGAFPEDHPLYLGmlgmhgtPAANEALAEADLVLAVGARFDDRVT-GNWDEF--APDAKIIHIDIDPAEIGKN 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 331 VEIVAPVVGDIGSCVEALLDGIRKDWKGAPSnWLETLRGKREANIAKMAPklmkNSSPMCFHSALGALRTVIKErpDAIL 410
Cdd:COG0028 310 YPVDLPIVGDAKAVLAALLEALEPRADDRAA-WLARIAAWRAEYLAAYAA----DDGPIKPQRVIAALREALPD--DAIV 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 411 VNEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIV 489
Cdd:COG0028 383 VTDVGQHQMWAARYLRFRRPRRFLTSGGLGTMGYGLPAAIGAKLaRPDRPVVAITGDGGFQMNLQELATAVRYGLPVKVV 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 490 IFNNNG---IYRGTDTDPTGRDPGTTvfVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEIDPAAGS 566
Cdd:COG0028 463 VLNNGGlgmVRQWQELFYGGRYSGTD--LPNPDFAKLAEAFGAKGERVETPEELEAALEEALASDGPALIDVRVDPEENP 540
|
....*...
gi 2030910552 567 ESGNIGSL 574
Cdd:COG0028 541 PGATLDEM 548
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
29-564 |
4.52e-88 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 282.77 E-value: 4.52e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 29 LVIDALKLNGIETIYNVPGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTALANA 108
Cdd:PRK05858 10 LAARRLKAHGVDTMFTLSGGHLFPLYDGAREEGIRLIDVRHEQTAAFAAEAWAKLTRVPGVAVLTAGPGVTNGMSAMAAA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 109 TTNCFPMILISGSSEReiVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLPAK-LF 187
Cdd:PRK05858 90 QFNQSPLVVLGGRAPA--LRWGMGSLQEIDHVPFVAPVTKFAATAQSAENAGRLVDQALQAAVTPHRGPVFVDFPMDhAF 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 188 SQvidADLGARSLVKVIdAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVPMSMAKGL 267
Cdd:PRK05858 168 SM---ADDDGRPGALTE-LPAGPTPDPDALARAAGLLAEAQRPVIMAGTDVWWGHAEAALLRLAEELGIPVLMNGMGRGV 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 268 LPDTHPLSAGAARSTALKDSDVVLLVGARLNWLLSHGkgkTWGepGSKRFIQIDIEPREMDSNVEIVAPVVGDIGSCVEA 347
Cdd:PRK05858 244 VPADHPLAFSRARGKALGEADVVLVVGVPMDFRLGFG---VFG--GTAQLVHVDDAPPQRAHHRPVAAGLYGDLSAILSA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 348 LLD--GIRKDWKGapsnWLETLRGKREANIAKMAPKLMKNSSPMCFHSALGALRTVIKErpDAILVNEGANTLDLARGII 425
Cdd:PRK05858 319 LAGagGDRTDHQG----WIEELRTAETAARARDAAELADDRDPIHPMRVYGELAPLLDR--DAIVIGDGGDFVSYAGRYI 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 426 DMYQPRKRLDVGTWGVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIfNNNGIYrGTDTDP 504
Cdd:PRK05858 393 DPYRPGCWLDPGPFGCLGTGPGYALAARLaRPSRQVVLLQGDGAFGFSLMDVDTLVRHNLPVVSVI-GNNGIW-GLEKHP 470
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 505 T----GRD------PGTtvfvknsRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEIDPAA 564
Cdd:PRK05858 471 MealyGYDvaadlrPGT-------RYDEVVRALGGHGELVTVPAELGPALERAFASGVPYLVNVLTDPSV 533
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
391-561 |
3.41e-74 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 233.96 E-value: 3.41e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 391 FHSALGALRTVIKErpDAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMGFAVAAAVET-GKPVLAVEGDSAF 469
Cdd:cd02004 1 PYRVLHELQEALPD--DAIIVSDGGNTMDWARYILRPRKPRHRLDAGTFGTLGVGLGYAIAAALARpDKRVVLVEGDGAF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 470 GFSGMEVETICRYELPVCIVIFNNNGIYRGTDTDP--TGRDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEA 547
Cdd:cd02004 79 GFSGMELETAVRYNLPIVVVVGNNGGWYQGLDGQQlsYGLGLPVTTLLPDTRYDLVAEAFGGKGELVTTPEELKPALKRA 158
|
170
....*....|....
gi 2030910552 548 MNSGKPTLINAEID 561
Cdd:cd02004 159 LASGKPALINVIID 172
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
21-567 |
4.79e-69 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 232.59 E-value: 4.79e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 21 PELTDGFHLViDALKLNGIETIYNVPGIPITDL-GRLAQAEG-LRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGF 98
Cdd:PRK08266 2 TTMTGGEAIV-AGLVAHGVDTVFGLPGAQLYWLfDALYKAGDrIRVIHTRHEQAAGYMAFGYARSTGRPGVCSVVPGPGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 99 LNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEM-DQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGG 177
Cdd:PRK08266 81 LNAGAALLTAYGCNSPVLCLTGQIPSALIGKGRGHLHEMpDQLATLRSFTKWAERIEHPSEAPALVAEAFQQMLSGRPRP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 178 VYLDLPAKLFSQVIDADlgarsLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAayAQADEAVRALVEESGIP 257
Cdd:PRK08266 161 VALEMPWDVFGQRAPVA-----AAPPLRPAPPPAPDPDAIAAAAALIAAAKNPMIFVGGGA--AGAGEEIRELAEMLQAP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 258 YVPMSMAKGLLPDTHPLSAGAARSTAL-KDSDVVLLVGARLNWLLSHGKGKtwgePGSKRFIQIDIEPREMD---SNVEI 333
Cdd:PRK08266 234 VVAFRSGRGIVSDRHPLGLNFAAAYELwPQTDVVIGIGSRLELPTFRWPWR----PDGLKVIRIDIDPTEMRrlkPDVAI 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 334 VApvvgDIGSCVEALLDGIRKDWKGAPSNWLETLRGKREAN--IAKMAPKlmknsspmcfHSALGALRTVIKErpDAILV 411
Cdd:PRK08266 310 VA----DAKAGTAALLDALSKAGSKRPSRRAELRELKAAARqrIQAVQPQ----------ASYLRAIREALPD--DGIFV 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 412 NEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVI 490
Cdd:PRK08266 374 DELSQVGFASWFAFPVYAPRTFVTCGYQGTLGYGFPTALGAKVaNPDRPVVSITGDGGFMFGVQELATAVQHNIGVVTVV 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 491 FNNN---GIYRGTDTDPTGRDPGTTvfVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLInaEIDPAAGSE 567
Cdd:PRK08266 454 FNNNaygNVRRDQKRRFGGRVVASD--LVNPDFVKLAESFGVAAFRVDSPEELRAALEAALAHGGPVLI--EVPVPRGSE 529
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
26-563 |
5.41e-60 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 209.61 E-value: 5.41e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 26 GFHLVIDALKLNGIETIYNVPG---IPITDLgrLAQAEgLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGL 102
Cdd:PRK06276 3 GAEAIIKALEAEGVKIIFGYPGgalLPFYDA--LYDSD-LIHILTRHEQAAAHAADGYARASGKVGVCVATSGPGATNLV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 103 TALANATTNCFPMILISGSSEREIVDlqQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDL 182
Cdd:PRK06276 80 TGIATAYADSSPVIALTGQVPTKLIG--NDAFQEIDALGIFMPITKHNFQIKKPEEIPEIFRAAFEIAKTGRPGPVHIDL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 183 PAKLfsQVIDADLGARSLVKVIDAAPAQLPAP---AAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYV 259
Cdd:PRK06276 158 PKDV--QEGELDLEKYPIPAKIDLPGYKPTTFghpLQIKKAAELIAEAERPVILAGGGVIISGASEELIELSELVKIPVC 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 260 PMSMAKGLLPDTHPLSAG-------AARSTALKDSDVVLLVGARLNwllshgkGKTWGEPGS----KRFIQIDIEPREMD 328
Cdd:PRK06276 236 TTLMGKGAFPEDHPLALGmvgmhgtKAANYSVTESDVLIAIGCRFS-------DRTTGDISSfapnAKIIHIDIDPAEIG 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 329 SNVEIVAPVVGDIGSCVEALLDGIRKDWKGAPSNWLETLRGKREANIakmaPKLMKNSSPMCFHSALGALRTVIKER--- 405
Cdd:PRK06276 309 KNVRVDVPIVGDAKNVLRDLLAELMKKEIKNKSEWLERVKKLKKESI----PRMDFDDKPIKPQRVIKELMEVLREIdps 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 406 PDAILVNE-GANTLDLARgIIDMYQPRKRLDVGTWGVMGIGMGFAVAAAVET-GKPVLAVEGDSAFGFSGMEVETICRYE 483
Cdd:PRK06276 385 KNTIITTDvGQNQMWMAH-FFKTSAPRSFISSGGLGTMGFGFPAAIGAKVAKpDANVIAITGDGGFLMNSQELATIAEYD 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 484 LPVCIVIFNN----------NGIY--RGTDTDpTGRDPGttvFVknsrydKMMEAFGGVGVNVTTPDELKRAVDEAMNSG 551
Cdd:PRK06276 464 IPVVICIFDNrtlgmvyqwqNLYYgkRQSEVH-LGETPD---FV------KLAESYGVKADRVEKPDEIKEALKEAIKSG 533
|
570
....*....|..
gi 2030910552 552 KPTLINAEIDPA 563
Cdd:PRK06276 534 EPYLLDIIIDPA 545
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
26-561 |
2.71e-58 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 204.18 E-value: 2.71e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 26 GFHLVIDALKLNGIETIYNVPGIPITDL-GRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTA 104
Cdd:PRK08527 5 GSQMVCEALKEEGVKVVFGYPGGAILNIyDEIYKQNYFKHILTRHEQAAVHAADGYARASGKVGVAIVTSGPGFTNAVTG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 105 LANATTNCFPMILISGSSEREIVDLQQgdYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLPA 184
Cdd:PRK08527 85 LATAYMDSIPLVLISGQVPNSLIGTDA--FQEIDAVGISRPCVKHNYLVKSIEELPRILKEAFYIARSGRPGPVHIDIPK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 185 KLFSQVidADLGARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVPMSMA 264
Cdd:PRK08527 163 DVTATL--GEFEYPKEISLKTYKPTYKGNSRQIKKAAEAIKEAKKPLFYLGGGAILSNASEEIRELVKKTGIPAVETLMA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 265 KGLLPDTHPLSAGA-------ARSTALKDSDVVLLVGARLNWLLShgkGKTWGEPGSKRFIQIDIEPREMDSNVEIVAPV 337
Cdd:PRK08527 241 RGVLRSDDPLLLGMlgmhgsyAANMAMSECDLLISLGARFDDRVT---GKLSEFAKHAKIIHVDIDPSSISKIVNADYPI 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 338 VGDIGSCVEALLDGIRKDWKGAPSNWLETLRGKREANiakmapklmknssPMCFHSAlgalRTVIKerPDAILVNEGANT 417
Cdd:PRK08527 318 VGDLKNVLKEMLEELKEENPTTYKEWREILKRYNELH-------------PLSYEDS----DEVLK--PQWVIERVGELL 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 418 LDLARGIIDMYQ-------------PRKRLDVGTWGVMGIGMGFAVAAAVETG-KPVLAVEGDSAFGFSGMEVETICRYE 483
Cdd:PRK08527 379 GDDAIISTDVGQhqmwvaqfypfnyPRQLATSGGLGTMGYGLPAALGAKLAVPdKVVINFTGDGSILMNIQELMTAVEYK 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 484 LPVCIVIFNNN--GIYRGTDTDPTGRDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEID 561
Cdd:PRK08527 459 IPVINIILNNNflGMVRQWQTFFYEERYSETDLSTQPDFVKLAESFGGIGFRVTTKEEFDKALKEALESDKVALIDVKID 538
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
30-561 |
3.15e-57 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 201.54 E-value: 3.15e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 30 VIDALKLNGIETIYNVPGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTALANAT 109
Cdd:PRK06048 14 IIKCLEKEGVEVIFGYPGGAIIPVYDELYDSDLRHILVRHEQAAAHAADGYARATGKVGVCVATSGPGATNLVTGIATAY 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 110 TNCFPMILISGSSEREIVDlqQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLPAKLfsQ 189
Cdd:PRK06048 94 MDSVPIVALTGQVPRSMIG--NDAFQEADITGITMPITKHNYLVQDAKDLPRIIKEAFHIASTGRPGPVLIDLPKDV--T 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 190 VIDADLGARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVPMSMAKGLLP 269
Cdd:PRK06048 170 TAEIDFDYPDKVELRGYKPTYKGNPQQIKRAAELIMKAERPIIYAGGGVISSNASEELVELAETIPAPVTTTLMGIGAIP 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 270 DTHPLSAGAA-------RSTALKDSDVVLLVGARLNwllSHGKGKTWGEPGSKRFIQIDIEPREMDSNVEIVAPVVGDIG 342
Cdd:PRK06048 250 TEHPLSLGMLgmhgtkyANYAIQESDLIIAVGARFD---DRVTGKLASFAPNAKIIHIDIDPAEISKNVKVDVPIVGDAK 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 343 SCVEALLDGI----RKDWKGAPSNWLET--LRGKREANIAKmaPK-LMKNSSPMCfhsalgalrtvikerPDAILVNEGA 415
Cdd:PRK06048 327 QVLKSLIKYVqycdRKEWLDKINQWKKEypLKYKEREDVIK--PQyVIEQIYELC---------------PDAIIVTEVG 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 416 NTLDLARGIIDMYQPRKRLDVGTWGVMGigMGFAVAAAVETGKP---VLAVEGDSAFGFSGMEVETICRYELPVCIVIFN 492
Cdd:PRK06048 390 QHQMWAAQYFKYKYPRTFITSGGLGTMG--YGFPAAIGAKVGKPdktVIDIAGDGSFQMNSQELATAVQNDIPVIVAILN 467
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2030910552 493 NN--GIYRGTDTDPTGRDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEID 561
Cdd:PRK06048 468 NGylGMVRQWQELFYDKRYSHTCIKGSVDFVKLAEAYGALGLRVEKPSEVRPAIEEAVASDRPVVIDFIVE 538
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
28-564 |
3.45e-56 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 197.89 E-value: 3.45e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 28 HLVIDALKLNGIETIYNVPGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTALAN 107
Cdd:PRK07524 6 EALVRLLEAYGVETVFGIPGVHTVELYRGLAGSGIRHVTPRHEQGAGFMADGYARVSGKPGVCFIITGPGMTNIATAMGQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 108 ATTNCFPMILISGSSEREIVDLQQGDYEEM-DQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLPAKL 186
Cdd:PRK07524 86 AYADSIPMLVISSVNRRASLGKGRGKLHELpDQRAMVAGVAAFSHTLMSAEDLPEVLARAFAVFDSARPRPVHIEIPLDV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 187 FSQVIDADLGARSLVKvidaaPAQLPAPAAIARALDVLKSAERPLIILGKGAayAQADEAVRALVEESGIPYVPMSMAKG 266
Cdd:PRK07524 166 LAAPADHLLPAPPTRP-----ARPGPAPAALAQAAERLAAARRPLILAGGGA--LAAAAALRALAERLDAPVALTINAKG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 267 LLPDTHPLSAGAARSTA-----LKDSDVVLLVGARLnwllshgkGKT-------WGEPGSKRFIQIDIEPREMDSNVEIV 334
Cdd:PRK07524 239 LLPAGHPLLLGASQSLPavralIAEADVVLAVGTEL--------GETdydvyfdGGFPLPGELIRIDIDPDQLARNYPPA 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 335 APVVGDIGSCVEALLDGI-----RKDWkGAPSnwletLRGKREANIAKMAPKlmknsspmcFHSALGALRTVIKERPDAI 409
Cdd:PRK07524 311 LALVGDARAALEALLARLpgqaaAADW-GAAR-----VAALRQALRAEWDPL---------TAAQVALLDTILAALPDAI 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 410 LVNEGANTLDLARGIIDMYQPRKRLDVGT-WGVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETICRYELPVC 487
Cdd:PRK07524 376 FVGDSTQPVYAGNLYFDADAPRRWFNASTgYGTLGYGLPAAIGAALgAPERPVVCLVGDGGLQFTLPELASAVEADLPLI 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 488 IVIFNNNGiYR-------GTDTDPTGRDPGTTVFVKNSRydkmmeAFGGVGVNVTTPDELKRAVDEAMNSGKPTLInaEI 560
Cdd:PRK07524 456 VLLWNNDG-YGeirrymvARDIEPVGVDPYTPDFIALAR------AFGCAAERVADLEQLQAALRAAFARPGPTLI--EV 526
|
....
gi 2030910552 561 DPAA 564
Cdd:PRK07524 527 DQAC 530
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
29-561 |
2.09e-55 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 196.20 E-value: 2.09e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 29 LVIDALKLNGIETIYNVPGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTALANA 108
Cdd:PRK08322 6 LFVKCLENEGVEYIFGIPGEENLDLLEALRDSSIKLILTRHEQGAAFMAATYGRLTGKAGVCLSTLGPGATNLVTGVAYA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 109 TTNCFPMILISGssEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLPaklfs 188
Cdd:PRK08322 86 QLGGMPMVAITG--QKPIKRSKQGSFQIVDVVAMMAPLTKWTRQIVSPDNIPEVVREAFRLAEEERPGAVHLELP----- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 189 QVIDADLGARSLVKViDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVPMSMAKGLL 268
Cdd:PRK08322 159 EDIAAEETDGKPLPR-SYSRRPYASPKAIERAAEAIQAAKNPLILIGAGANRKTASKALTEFVDKTGIPFFTTQMGKGVI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 269 PDTHPLSAGAAR-------STALKDSDVVLLVGarlnwllsHG----KGKTWGEPGSKRFIQIDIEPREMDSNVEIVAPV 337
Cdd:PRK08322 238 PETHPLSLGTAGlsqgdyvHCAIEHADLIINVG--------HDviekPPFFMNPNGDKKVIHINFLPAEVDPVYFPQVEV 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 338 VGDIGSCVEALLDGIRKDWkGAPSNWLETLRGKREANIAKMApklMKNSSPMCFHSALGALRTVIkERPDAILVNEGANT 417
Cdd:PRK08322 310 VGDIANSLWQLKERLADQP-HWDFPRFLKIREAIEAHLEEGA---DDDRFPMKPQRIVADLRKVM-PDDDIVILDNGAYK 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 418 LDLARgiidMYQPRKR----LDVGtWGVMGIGMGFAVAAA-VETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIFN 492
Cdd:PRK08322 385 IWFAR----NYRAYEPntclLDNA-LATMGAGLPSAIAAKlVHPDRKVLAVCGDGGFMMNSQELETAVRLGLPLVVLILN 459
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2030910552 493 NN--GIYRGTDTDPTGRDPGTTV----FVknsrydKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEID 561
Cdd:PRK08322 460 DNayGMIRWKQENMGFEDFGLDFgnpdFV------KYAESYGAKGYRVESADDLLPTLEEALAQPGVHVIDCPVD 528
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
14-558 |
1.24e-52 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 189.88 E-value: 1.24e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 14 GAMPHEEPELTDGFHLVIDALKLNGIETIYNVPG---IPITDLGRLAQAEG-LRVISFRHEQNAGNAAAIAGFLTKKPGI 89
Cdd:PRK07418 9 GDSTTVTPQRATGAYALMDSLKRHGVKHIFGYPGgaiLPIYDELYKAEAEGwLKHILVRHEQGAAHAADGYARATGKVGV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 90 CLTVSAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQgdYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRA 169
Cdd:PRK07418 89 CFGTSGPGATNLVTGIATAQMDSVPMVVITGQVPRPAIGTDA--FQETDIFGITLPIVKHSYVVRDPSDMARIVAEAFHI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 170 AVSGRPGGVYLDLPAKLFSQVIDADLGARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRA 249
Cdd:PRK07418 167 ASSGRPGPVLIDIPKDVGQEEFDYVPVEPGSVKPPGYRPTVKGNPRQINAALKLIEEAERPLLYVGGGAISAGAHAELKE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 250 LVEESGIPYVPMSMAKGLLPDTHPLSAG-------AARSTALKDSDVVLLVGARLNWLLShGKGKTWGEpgSKRFIQIDI 322
Cdd:PRK07418 247 LAERFQIPVTTTLMGKGAFDEHHPLSVGmlgmhgtAYANFAVTECDLLIAVGARFDDRVT-GKLDEFAS--RAKVIHIDI 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 323 EPREMDSNVEIVAPVVGDIGSCVEALLDGIRKDwKGAP--SNWLETLRGKREaNIAKMAPKLMKNSSPmcfHSALGALRt 400
Cdd:PRK07418 324 DPAEVGKNRRPDVPIVGDVRKVLVKLLERSLEP-TTPPrtQAWLERINRWKQ-DYPLVVPPYEGEIYP---QEVLLAVR- 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 401 viKERPDAILvneganTLDLarGIIDMYQ-------PRKRLDVGTWGVMGIGMGFAVAAAVETGK-PVLAVEGDSAFGFS 472
Cdd:PRK07418 398 --DLAPDAYY------TTDV--GQHQMWAaqflrngPRRWISSAGLGTMGFGMPAAMGVKVALPDeEVICIAGDASFLMN 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 473 GMEVETICRYELPVCIVIFNN--NGIYR-------GTDTDPTGRDPGTTVFVknsrydKMMEAFGGVGVNVTTPDELKRA 543
Cdd:PRK07418 468 IQELGTLAQYGINVKTVIINNgwQGMVRqwqesfyGERYSASNMEPGMPDFV------KLAEAFGVKGMVISERDQLKDA 541
|
570
....*....|....*
gi 2030910552 544 VDEAMNSGKPTLINA 558
Cdd:PRK07418 542 IAEALAHDGPVLIDV 556
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
26-561 |
1.70e-50 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 183.12 E-value: 1.70e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 26 GFHLVIDALKLNGIETIYNVPGI---PITD--LGRLAQAEgLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLN 100
Cdd:PRK06456 4 GARILVDSLKREGVKVIFGIPGLsnmQIYDafVEDLANGE-LRHVLMRHEQAAAHAADGYARASGVPGVCTATSGPGTTN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 101 GLTALANATTNCFPMILISGSSEREIVDlqQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYL 180
Cdd:PRK06456 83 LVTGLITAYWDSSPVIAITGQVPRSVMG--KMAFQEADAMGVFENVTKYVIGIKRIDEIPQWIKNAFYIATTGRPGPVVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 181 DLPAKLFSQVIDaDL---------GARSLVKVIDaapaqlpaPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALV 251
Cdd:PRK06456 161 DIPRDIFYEKME-EIkwpekplvkGYRDFPTRID--------RLALKKAAEILINAERPIILVGTGVVWSNATPEVLELA 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 252 EESGIPYVPMSMAKGLLPDTHPLSAG-------AARSTALKDSDVVLLVGARLN--WLLSHGKGKTWGepgsKRFIQIDI 322
Cdd:PRK06456 232 ELLHIPIVSTFPGKTAIPHDHPLYFGpmgyygrAEASMAALESDAMLVVGARFSdrTFTSYDEMVETR----KKFIMVNI 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 323 EPREMDSNVEIVAPVVGDIGSCVEALLDGIRK-DWKGAPSNWLETLRGKRE--------ANIAKMAP-KLMKnsspmcfh 392
Cdd:PRK06456 308 DPTDGEKAIKVDVGIYGNAKIILRELIKAITElGQKRDRSAWLKRVKEYKEyysqfyytEENGKLKPwKIMK-------- 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 393 salgALRTVIkerPDAILVNEGANTLDLARGII-DMYQPRKRLDVGTWGVMGIGMGFAVAAAVetGKP---VLAVEGDSA 468
Cdd:PRK06456 380 ----TIRQAL---PRDAIVTTGVGQHQMWAEVFwEVLEPRTFLTSSGMGTMGFGLPAAMGAKL--ARPdkvVVDLDGDGS 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 469 FGFSGMEVETICRYELPVCIVIFNNN--GIYRGTDTDPTGRDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDE 546
Cdd:PRK06456 451 FLMTGTNLATAVDEHIPVISVIFDNRtlGLVRQVQDLFFGKRIVGVDYGPSPDFVKLAEAFGALGFNVTTYEDIEKSLKS 530
|
570
....*....|....*
gi 2030910552 547 AMNSGKPTLINAEID 561
Cdd:PRK06456 531 AIKEDIPAVIRVPVD 545
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
26-562 |
1.56e-49 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 180.29 E-value: 1.56e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 26 GFHLVIDALKLNGIETIYNVPG---IPITDlgRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGL 102
Cdd:PRK08155 15 GAELIVRLLERQGIRIVTGIPGgaiLPLYD--ALSQSTQIRHILARHEQGAGFIAQGMARTTGKPAVCMACSGPGATNLV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 103 TALANATTNCFPMILISGSSEREIVDLQQgdYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDL 182
Cdd:PRK08155 93 TAIADARLDSIPLVCITGQVPASMIGTDA--FQEVDTYGISIPITKHNYLVRDIEELPQVISDAFRIAQSGRPGPVWIDI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 183 PAKLFSQVIDADlgarSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVPMS 262
Cdd:PRK08155 171 PKDVQTAVIELE----ALPAPAEKDAAPAFDEESIRDAAAMINAAKRPVLYLGGGVINSGAPARARELAEKAQLPTTMTL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 263 MAKGLLPDTHPLSAG-----AARST--ALKDSDVVLLVGARLNwllSHGKGKTWGEPGSKRFIQIDIEPREMDsnvEIVA 335
Cdd:PRK08155 247 MALGMLPKAHPLSLGmlgmhGARSTnyILQEADLLIVLGARFD---DRAIGKTEQFCPNAKIIHVDIDRAELG---KIKQ 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 336 PVV---GDIGSCVEALLDGIRKDwkgAPSNWLETLRG-KREaniakmAPKLMKNSS-PMCFHsalGALRTVIkerpdAIL 410
Cdd:PRK08155 321 PHVaiqADVDDVLAQLLPLVEAQ---PRAEWHQLVADlQRE------FPCPIPKADdPLSHY---GLINAVA-----ACV 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 411 VNEGANTLDLarGIIDMY--------QPRKRLDVGTWGVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETICR 481
Cdd:PRK08155 384 DDNAIITTDV--GQHQMWtaqayplnRPRQWLTSGGLGTMGFGLPAAIGAALaNPERKVLCFSGDGSLMMNIQEMATAAE 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 482 YELPVCIVIFNNN--GIYRGTDTDPTGRD------PGTTVFVknsrydKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKP 553
Cdd:PRK08155 462 NQLDVKIILMNNEalGLVHQQQSLFYGQRvfaatyPGKINFM------QIAAGFGLETCDLNNEADPQAALQEAINRPGP 535
|
....*....
gi 2030910552 554 TLINAEIDP 562
Cdd:PRK08155 536 ALIHVRIDA 544
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
15-564 |
2.23e-49 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 180.34 E-value: 2.23e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 15 AMPHEEPELTdGFHLVIDALKLNGIETIYNvPGIPiTDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVS 94
Cdd:PRK06112 6 SAPGFTLNGT-VAHAIARALKRHGVEQIFG-QSLP-SALFLAAEAIGIRQIAYRTENAGGAMADGYARVSGKVAVVTAQN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 95 APGFLNGLTALANATTNCFPMILISGSSEREIVDlqQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGR 174
Cdd:PRK06112 83 GPAATLLVAPLAEALKASVPIVALVQDVNRDQTD--RNAFQELDHIALFQSCTKWVRRVTVAERIDDYVDQAFTAATSGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 175 PGGVYLDLPAKLFSQVIDA-------DLGARSLVKVIdaapaqlPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAV 247
Cdd:PRK06112 161 PGPVVLLLPADLLTAAAAApaaprsnSLGHFPLDRTV-------PAPQRLAEAASLLAQAQRPVVVAGGGVHISGASAAL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 248 RALVEESGIPYVPMSMAKGLLPDTHPLSAG------AARSTA------LKDSDVVLLVGARLNwllsHGKGKTWGE-PGS 314
Cdd:PRK06112 234 AALQSLAGLPVATTNMGKGAVDETHPLSLGvvgslmGPRSPGrhlrdlVREADVVLLVGTRTN----QNGTDSWSLyPEQ 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 315 KRFIQIDIEPREMDSNVEIVApVVGDIGSCVEALLDGIRK----DWKGAPSNWLETLRGKREANIAKMAPKLMKNSSPMC 390
Cdd:PRK06112 310 AQYIHIDVDGEEVGRNYEALR-LVGDARLTLAALTDALRGrdlaARAGRRAALEPAIAAGREAHREDSAPVALSDASPIR 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 391 FHSALGALRTVIKerPDAILVNEGANTLDLARGIIDMYQPRKRLdVGTWGVMGIGMG--FAVAAAV-ETGKPVLAVEGDS 467
Cdd:PRK06112 389 PERIMAELQAVLT--GDTIVVADASYSSIWVANFLTARRAGMRF-LTPRGLAGLGWGvpMAIGAKVaRPGAPVICLVGDG 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 468 AFGFSGMEVETICRYELPVCIVIFNNN--GIYRGTDTDPTGrDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVD 545
Cdd:PRK06112 466 GFAHVWAELETARRMGVPVTIVVLNNGilGFQKHAETVKFG-THTDACHFAAVDHAAIARACGCDGVRVEDPAELAQALA 544
|
570
....*....|....*....
gi 2030910552 546 EAMNSGKPTLINAEIDPAA 564
Cdd:PRK06112 545 AAMAAPGPTLIEVITDPSA 563
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
29-561 |
2.90e-48 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 176.58 E-value: 2.90e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 29 LVIDALKLNGIETIYNVPGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTALANA 108
Cdd:PRK08617 10 LVVDSLINQGVKYVFGIPGAKIDRVFDALEDSGPELIVTRHEQNAAFMAAAIGRLTGKPGVVLVTSGPGVSNLATGLVTA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 109 TTNCFPMILISGSSEREivDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLP----- 183
Cdd:PRK08617 90 TAEGDPVVAIGGQVKRA--DRLKRTHQSMDNVALFRPITKYSAEVQDPDNLSEVLANAFRAAESGRPGAAFVSLPqdvvd 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 184 ----AKLFSQVIDADLGARSLVKVidaapaqlpapaaiARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYV 259
Cdd:PRK08617 168 apvtSKAIAPLSKPKLGPASPEDI--------------NYLAELIKNAKLPVLLLGMRASSPEVTAAIRRLLERTNLPVV 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 260 PMSMAKGLLPdtHPLSA------GAARSTA----LKDSDVVLLVG-------ARLnwllshgkgktWGEPGSKRFIQIDI 322
Cdd:PRK08617 234 ETFQAAGVIS--RELEDhffgrvGLFRNQPgdelLKKADLVITIGydpieyePRN-----------WNSEGDATIIHIDV 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 323 EPREMDSNVEIVAPVVGDIGSCVEAL---LDGIRkdwkgAPSNWLETLRGKREANIAKMAPKLMKNSSPMcfH--SALGA 397
Cdd:PRK08617 301 LPAEIDNYYQPERELIGDIAATLDLLaekLDGLS-----LSPQSLEILEELRAQLEELAERPARLEEGAV--HplRIIRA 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 398 LRTVIKErpDAILvneganTLDLARGIIDM------YQPRKRLDVGTWGVMGIGMGFAVAAA-VETGKPVLAVEGDSAFG 470
Cdd:PRK08617 374 LQDIVTD--DTTV------TVDVGSHYIWMaryfrsYEPRHLLFSNGMQTLGVALPWAIAAAlVRPGKKVVSVSGDGGFL 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 471 FSGMEVETICRYELPVCIVIFNNNGI----------YrgtdtdptGRDPGttvfVKNSRYD--KMMEAFGGVGVNVTTPD 538
Cdd:PRK08617 446 FSAMELETAVRLKLNIVHIIWNDGHYnmvefqeemkY--------GRSSG----VDFGPVDfvKYAESFGAKGLRVTSPD 513
|
570 580
....*....|....*....|...
gi 2030910552 539 ELKRAVDEAMNSGKPTLINAEID 561
Cdd:PRK08617 514 ELEPVLREALATDGPVVIDIPVD 536
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
16-564 |
5.53e-48 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 175.83 E-value: 5.53e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 16 MPHEEPELTDGfHLVIDALKLNGIETIYNVPG---IPITDlgRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLT 92
Cdd:PRK08199 1 MTSTPRARTGG-QILVDALRANGVERVFCVPGesyLAVLD--ALHDETDIRVIVCRQEGGAAMMAEAYGKLTGRPGICFV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 93 VSAPGFLNGLTALANATTNCFPMILISGSSEREIVD---LQQGDYEEMDQlaiakPLCKAAFRVLHAADIGIGVARAIRA 169
Cdd:PRK08199 78 TRGPGATNASIGVHTAFQDSTPMILFVGQVARDFREreaFQEIDYRRMFG-----PMAKWVAEIDDAARIPELVSRAFHV 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 170 AVSGRPGGVYLDLPAKLFSQVIDADLGARslVKVIDAAPAQLPAPAAIARaldvLKSAERPLIILGKGAAYAQADEAVRA 249
Cdd:PRK08199 153 ATSGRPGPVVLALPEDVLSETAEVPDAPP--YRRVAAAPGAADLARLAEL----LARAERPLVILGGSGWTEAAVADLRA 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 250 LVEESGIPYVPMSMAKGLLPDTHPLSAG----------AARstaLKDSDVVLLVGARLNWLLShgKGKTWGE-PGSK-RF 317
Cdd:PRK08199 227 FAERWGLPVACAFRRQDLFDNRHPNYAGdlglginpalAAR---IREADLVLAVGTRLGEVTT--QGYTLLDiPVPRqTL 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 318 IQIDIEPREMDSNVEIVAPVVGDIGSCVEALLD---GIRKDWKGapsnWLETLRGKREANIAK-MAPKLMKNSSPMCFhs 393
Cdd:PRK08199 302 VHVHPDAEELGRVYRPDLAIVADPAAFAAALAAlepPASPAWAE----WTAAAHADYLAWSAPlPGPGAVQLGEVMAW-- 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 394 algaLRTVIKErpDAILVNEGAN-TLDLARgiidmYQPRKRLDVG---TWGVMGIGMGFAVAAAVET-GKPVLAVEGDSA 468
Cdd:PRK08199 376 ----LRERLPA--DAIITNGAGNyATWLHR-----FFRFRRYRTQlapTSGSMGYGLPAAIAAKLLFpERTVVAFAGDGC 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 469 FGFSGMEVETICRYELPVCIVIFnNNGIYrGT-----DTDPTGRDPGTTvfVKNSRYDKMMEAFGGVGVNVTTPDELKRA 543
Cdd:PRK08199 445 FLMNGQELATAVQYGLPIIVIVV-NNGMY-GTirmhqEREYPGRVSGTD--LTNPDFAALARAYGGHGETVERTEDFAPA 520
|
570 580
....*....|....*....|.
gi 2030910552 544 VDEAMNSGKPTLINAEIDPAA 564
Cdd:PRK08199 521 FERALASGKPALIEIRIDPEA 541
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
34-558 |
1.17e-47 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 175.57 E-value: 1.17e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 34 LKLNGIETIYNVPGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTALANATTNCF 113
Cdd:PRK07525 16 LQAHGITHAFGIIGSAFMDASDLFPPAGIRFIDVAHEQNAGHMADGYTRVTGRMGMVIGQNGPGITNFVTAVATAYWAHT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 114 PMILISGSSEREIVDlqQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRpGGVYLDLPAKLFSQVIDA 193
Cdd:PRK07525 96 PVVLVTPQAGTKTIG--QGGFQEAEQMPMFEDMTKYQEEVRDPSRMAEVLNRVFDKAKRES-GPAQINIPRDYFYGVIDV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 194 DL-----------GARSLVKvidaapaqlpapaaiarALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVPMS 262
Cdd:PRK07525 173 EIpqpvrlergagGEQSLAE-----------------AAELLSEAKFPVILSGAGVVLSDAIEECKALAERLDAPVACGY 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 263 MAKGLLPDTHPLSAG--------AARSTaLKDSDVVLLVGARLNW---LLSHGKgKTWgePGSKRFIQIDIEPREMDSNV 331
Cdd:PRK07525 236 LHNDAFPGSHPLWVGplgyngskAAMEL-IAKADVVLALGTRLNPfgtLPQYGI-DYW--PKDAKIIQVDINPDRIGLTK 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 332 EIVAPVVGDIGSCVEALLDGIRKDWKG-------------APSNWLETL---------------RGKREANIAKMAPKLm 383
Cdd:PRK07525 312 KVSVGICGDAKAVARELLARLAERLAGdagreerkaliaaEKSAWEQELsswdhedddpgtdwnEEARARKPDYMHPRQ- 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 384 knsspmcfhsalgALRTVIKERP-DAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMGFAVAAAV-ETGKPVL 461
Cdd:PRK07525 391 -------------ALREIQKALPeDAIVSTDIGNNCSIANSYLRFEKGRKYLAPGSFGNCGYAFPAIIGAKIaCPDRPVV 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 462 AVEGDSAFGFSGMEVETICRYELPVCIVIFNN--------------NGIYRGTDTDPtgrdpgttvfvkNSRYDKMMEAF 527
Cdd:PRK07525 458 GFAGDGAWGISMNEVMTAVRHNWPVTAVVFRNyqwgaekknqvdfyNNRFVGTELDN------------NVSYAGIAEAM 525
|
570 580 590
....*....|....*....|....*....|....
gi 2030910552 528 GGVGVNVTTPDELKRAVDEAM---NSGKPTLINA 558
Cdd:PRK07525 526 GAEGVVVDTQEELGPALKRAIdaqNEGKTTVIEI 559
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
15-557 |
4.66e-47 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 173.62 E-value: 4.66e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 15 AMPHEEPELTDGFHLVIDALKLNGIETIYNVPGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVS 94
Cdd:PRK06725 6 TYEKLQCEEVTGAGHVIQCLKKLGVTTVFGYPGGAILPVYDALYESGLKHILTRHEQAAIHAAEGYARASGKVGVVFATS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 95 APGFLNGLTALANATTNCFPMILISGSSEREIVDlqQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGR 174
Cdd:PRK06725 86 GPGATNLVTGLADAYMDSIPLVVITGQVATPLIG--KDGFQEADVVGITVPVTKHNYQVRDVNQLSRIVQEAFYIAESGR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 175 PGGVYLDLPAKLFSQVIDADLGARslVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEES 254
Cdd:PRK06725 164 PGPVLIDIPKDVQNEKVTSFYNEV--VEIPGYKPEPRPDSMKLREVAKAISKAKRPLLYIGGGVIHSGGSEELIEFAREN 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 255 GIPYVPMSMAKGLLPDTHPLSAGA-------ARSTALKDSDVVLLVGARLNWLLShGKGKTWgEPGSKRfIQIDIEPREM 327
Cdd:PRK06725 242 RIPVVSTLMGLGAYPPGDPLFLGMlgmhgtyAANMAVTECDLLLALGVRFDDRVT-GKLELF-SPHSKK-VHIDIDPSEF 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 328 DSNVEIVAPVVGDIGSCVEALLDGI----RKDWKGAPSNWLETLRGKREANIAKMAPKLMKNsspMCFHSALGalrtvik 403
Cdd:PRK06725 319 HKNVAVEYPVVGDVKKALHMLLHMSihtqTDEWLQKVKTWKEEYPLSYKQKESELKPQHVIN---LVSELTNG------- 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 404 erpDAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMgiGMGFAVAAAVETGKP---VLAVEGDSAFGFSGMEVETIC 480
Cdd:PRK06725 389 ---EAIVTTEVGQHQMWAAHFYKAKNPRTFLTSGGLGTM--GFGFPAAIGAQLAKEeelVICIAGDASFQMNIQELQTIA 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 481 RYELPVCIVIFNNN--GIYRG-----TDTDPTGRDPGTTVFVknsrydKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKP 553
Cdd:PRK06725 464 ENNIPVKVFIINNKflGMVRQwqemfYENRLSESKIGSPDFV------KVAEAYGVKGLRATNSTEAKQVMLEAFAHEGP 537
|
....
gi 2030910552 554 TLIN 557
Cdd:PRK06725 538 VVVD 541
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
12-548 |
7.11e-43 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 162.46 E-value: 7.11e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 12 TAGAMPHEEPELTDGFHLVIDALKLNGIETIYNVPG---IPITDlgRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPG 88
Cdd:PRK07789 19 PAARPRIVAPERMTGAQAVVRSLEELGVDVVFGIPGgaiLPVYD--PLFDSTKVRHVLVRHEQGAGHAAEGYAQATGRVG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 89 ICLTVSAPGFLNGLTALANATTNCFPMILISGssereivdlQQGD-------YEEMDQLAIAKPLCKAAFRVLHAADIGI 161
Cdd:PRK07789 97 VCMATSGPGATNLVTPIADANMDSVPVVAITG---------QVGRgligtdaFQEADIVGITMPITKHNFLVTDADDIPR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 162 GVARAIRAAVSGRPGGVYLDLPAKL------FSQVIDADL-GARSLV----KVIDAapaqlpapaaiarALDVLKSAERP 230
Cdd:PRK07789 168 VIAEAFHIASTGRPGPVLVDIPKDAlqaqttFSWPPRMDLpGYRPVTkphgKQIRE-------------AAKLIAAARRP 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 231 LIILGKGAAYAQADEAVRALVEESGIPYVPMSMAKGLLPDTHPLSAG-------AARSTALKDSDVVLLVGARLNWLLSh 303
Cdd:PRK07789 235 VLYVGGGVIRAEASAELRELAELTGIPVVTTLMARGAFPDSHPQHLGmpgmhgtVAAVAALQRSDLLIALGARFDDRVT- 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 304 GKGKTWGePGSKrFIQIDIEPREMDSNVEIVAPVVGDIGSCVEALLDGIRKDWKGAP----SNWLETLRGKREANIAKMA 379
Cdd:PRK07789 314 GKLDSFA-PDAK-VIHADIDPAEIGKNRHADVPIVGDVKEVIAELIAALRAEHAAGGkpdlTAWWAYLDGWRETYPLGYD 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 380 PKLMKNSSPMCFHSALGALRTvikerPDAILVNEGANTLDLARGIIDMYQPRKRLDVGtwgvmGIG-MGFAVAAAV---- 454
Cdd:PRK07789 392 EPSDGSLAPQYVIERLGEIAG-----PDAIYVAGVGQHQMWAAQFIDYEKPRTWLNSG-----GLGtMGYAVPAAMgakv 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 455 -ETGKPVLAVEGDSAFGFSGMEVETiCRYE-LPVCIVIFNN--------------NGIYRGTDTDP-TGRDPGttvFVkn 517
Cdd:PRK07789 462 gRPDKEVWAIDGDGCFQMTNQELAT-CAIEgIPIKVALINNgnlgmvrqwqtlfyEERYSNTDLHThSHRIPD---FV-- 535
|
570 580 590
....*....|....*....|....*....|.
gi 2030910552 518 srydKMMEAFGGVGVNVTTPDELKRAVDEAM 548
Cdd:PRK07789 536 ----KLAEAYGCVGLRCEREEDVDAVIEKAR 562
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
26-194 |
1.02e-42 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 150.85 E-value: 1.02e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 26 GFHLVIDALKLNGIETIYNVPGIPITDLGR-LAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTA 104
Cdd:pfam02776 1 GAEALADVLKALGVDTVFGVPGGHILPLLDaLAKSPGIRYVLTRHEQGAAFAADGYARATGKPGVVLVTSGPGATNALTG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 105 LANATTNCFPMILISGSSEREIVDlQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLPA 184
Cdd:pfam02776 81 LANAYVDSVPLLVISGQRPRSLVG-RGALQQELDQLALFRPVTKWAVRVTSADEIPEVLRRAFRAALSGRPGPVYLEIPL 159
|
170
....*....|
gi 2030910552 185 KLFSQVIDAD 194
Cdd:pfam02776 160 DVLLEEVDED 169
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
22-548 |
2.08e-42 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 160.76 E-value: 2.08e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 22 ELTDGFHLVIDALKLNGIETIYNVPGIPITDL-GRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLN 100
Cdd:PRK08979 2 EMLSGASMIVRSLIDEGVKHIFGYPGGSVLDIyDALHEKSGIEHILVRHEQAAVHMADGYARATGKVGVVLVTSGPGATN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 101 GLTALANATTNCFPMILISGSSEREIVDlqQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYL 180
Cdd:PRK08979 82 TITGIATAYMDSIPMVVLSGQVPSNLIG--NDAFQECDMIGISRPVVKHSFLVKDAEDIPEIIKKAFYIASTGRPGPVVI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 181 DLPAKLFSQVIDADLGARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVP 260
Cdd:PRK08979 160 DLPKDCLNPAILHPYEYPESIKMRSYNPTTSGHKGQIKRGLQALLAAKKPVLYVGGGAIISGADKQILQLAEKLNLPVVS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 261 MSMAKGLLPDTHPLSAGA-------ARSTALKDSDVVLLVGARLNWLLSHGKGKTWgePGSKrFIQIDIEPREMDSNVEI 333
Cdd:PRK08979 240 TLMGLGAFPGTHKNSLGMlgmhgryEANMAMHNADLIFGIGVRFDDRTTNNLEKYC--PNAT-ILHIDIDPSSISKTVRV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 334 VAPVVGDIGSCVEALL-----DGIRKDwKGAPSNWLETLRGKREANIAKMApklmKNSSPMCFHSALGALRTVIKErpDA 408
Cdd:PRK08979 317 DIPIVGSADKVLDSMLalldeSGETND-EAAIASWWNEIEVWRSRNCLAYD----KSSERIKPQQVIETLYKLTNG--DA 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 409 ILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIG----MGFAVAAAVETgkpVLAVEGDSAFGFSGMEVETICRYEL 484
Cdd:PRK08979 390 YVASDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGlpaaMGVKFAMPDET---VVCVTGDGSIQMNIQELSTALQYDI 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 485 PVCIVIFNN----------NGIYRGTDTdptgrdpgttvfvkNSRYD------KMMEAFGGVGVNVTTPDELKRAVDEAM 548
Cdd:PRK08979 467 PVKIINLNNrflgmvkqwqDMIYQGRHS--------------HSYMDsvpdfaKIAEAYGHVGIRISDPDELESGLEKAL 532
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
15-556 |
6.48e-42 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 159.21 E-value: 6.48e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 15 AMPHE----EPELTDGFHLVIDALKLNGIETIYnvpGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLT--KKPG 88
Cdd:PRK06154 7 ALPNAhlpaEAKTMKVAEAVAEILKEEGVELLF---GFPVNELFDAAAAAGIRPVIARTERVAVHMADGYARATsgERVG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 89 ICLTVSAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQqgdyEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIR 168
Cdd:PRK06154 84 VFAVQYGPGAENAFGGVAQAYGDSVPVLFLPTGYPRGSTDVA----PNFESLRNYRHITKWCEQVTLPDEVPELMRRAFT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 169 AAVSGRPGGVYLDLPAKLFSQvidaDLGARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVR 248
Cdd:PRK06154 160 RLRNGRPGPVVLELPVDVLAE----ELDELPLDHRPSRRSRPGADPVEVVEAAALLLAAERPVIYAGQGVLYAQATPELK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 249 ALVEESGIPYVPMSMAKGLLPDTHPLSAGAA-----RSTA--LKDSDVVLLVGA---RLNWLLSHGKGKTwgepgskrFI 318
Cdd:PRK06154 236 ELAELLEIPVMTTLNGKSAFPEDHPLALGSGgrarpATVAhfLREADVLFGIGCsltRSYYGLPMPEGKT--------II 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 319 QIDIEPREMDSNVEIVAPVVGDIGSCVEALLDGIRKDWKGAPSNWLET---LRGKREANIAKMAPKLMKNSSPMCFHSAL 395
Cdd:PRK06154 308 HSTLDDADLNKDYPIDHGLVGDAALVLKQMIEELRRRVGPDRGRAQQVaaeIEAVRAAWLAKWMPKLTSDSTPINPYRVV 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 396 GALRTVIKERpDAILVNEGANTLDLargIIDMYQPRKRLDVGTWGV---MGIGMGFAVAAA-VETGKPVLAVEGDSAFGF 471
Cdd:PRK06154 388 WELQHAVDIK-TVIITHDAGSPRDQ---LSPFYVASRPGSYLGWGKttqLGYGLGLAMGAKlARPDALVINLWGDAAFGM 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 472 SGMEVETICRYELPVCIVIFNNN--GIYrgTDTDPTGRDPGTTVFVKNSrYDKMMEAFGGVGVNVTTPDELKRAVDEAM- 548
Cdd:PRK06154 464 TGMDFETAVRERIPILTILLNNFsmGGY--DKVMPVSTTKYRATDISGD-YAAIARALGGYGERVEDPEMLVPALLRALr 540
|
570
....*....|
gi 2030910552 549 --NSGKPTLI 556
Cdd:PRK06154 541 kvKEGTPALL 550
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
28-184 |
1.06e-41 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 147.68 E-value: 1.06e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 28 HLVIDALKLNGIETIYNVPGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTALAN 107
Cdd:cd07035 1 DALVEALKAEGVDHVFGVPGGAILPLLDALARSGIRYILVRHEQGAVGMADGYARATGKPGVVLVTSGPGLTNAVTGLAN 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2030910552 108 ATTNCFPMILISGSSEREivDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLPA 184
Cdd:cd07035 81 AYLDSIPLLVITGQRPTA--GEGRGAFQEIDQVALFRPITKWAYRVTSPEEIPEALRRAFRIALSGRPGPVALDLPK 155
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
22-579 |
1.41e-41 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 158.32 E-value: 1.41e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 22 ELTDGFHLvIDALKLNGIETIYNVPG---IPITDLGRLAQAEGL-RVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPG 97
Cdd:CHL00099 9 EKTGAFAL-IDSLVRHGVKHIFGYPGgaiLPIYDELYAWEKKGLiKHILVRHEQGAAHAADGYARSTGKVGVCFATSGPG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 98 FLNGLTALANATTNCFPMILISGSSEREIVDLQQgdYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGG 177
Cdd:CHL00099 88 ATNLVTGIATAQMDSVPLLVITGQVGRAFIGTDA--FQEVDIFGITLPIVKHSYVVRDARDISRIVAEAFYIAKHGRPGP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 178 VYLDLPA-----KLFSQVIDAdlgARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVE 252
Cdd:CHL00099 166 VLIDIPKdvgleKFDYYPPEP---GNTIIKILGCRPIYKPTIKRIEQAAKLILQSSQPLLYVGGGAIISDAHQEITELAE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 253 ESGIPYVPMSMAKGLLPDTHPLSAG-------AARSTALKDSDVVLLVGARLNWLLShgkGKTWGEPGSKRFIQIDIEPR 325
Cdd:CHL00099 243 LYKIPVTTTLMGKGIFDEDHPLCLGmlgmhgtAYANFAVSECDLLIALGARFDDRVT---GKLDEFACNAQVIHIDIDPA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 326 EMDSNVEIVAPVVGDIGSCVEALLDGIRKDWKGAPS----NWLETLRGKREAnIAKMAPKLMKNSSPMcfhsalGALRTV 401
Cdd:CHL00099 320 EIGKNRIPQVAIVGDVKKVLQELLELLKNSPNLLESeqtqAWRERINRWRKE-YPLLIPKPSTSLSPQ------EVINEI 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 402 IKERPDAILvneganTLDLarGIIDMY-------QPRKRLDVGTWGVMGIGMGFAVAAAVETGK-PVLAVEGDSAFGFSG 473
Cdd:CHL00099 393 SQLAPDAYF------TTDV--GQHQMWaaqflkcKPRKWLSSAGLGTMGYGLPAAIGAQIAHPNeLVICISGDASFQMNL 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 474 MEVETICRYELPVCIVIFNN--NGIYR-------GTDTDPTGRDPGTTVFVknsrydKMMEAFGGVGVNVTTPDELKRAV 544
Cdd:CHL00099 465 QELGTIAQYNLPIKIIIINNkwQGMVRqwqqafyGERYSHSNMEEGAPDFV------KLAEAYGIKGLRIKSRKDLKSSL 538
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 2030910552 545 DEAMNSGKPTLINAEIDP--------AAG-SESGNIGSLNPQST 579
Cdd:CHL00099 539 KEALDYDGPVLIDCQVIEdencypmvAPGkSNSQMIGILKQSTT 582
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
19-560 |
3.42e-41 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 156.91 E-value: 3.42e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 19 EEPelTDGFHLVIDALKLNGIETIYNVPG---IPITDlgRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSA 95
Cdd:PRK07282 7 ESP--KSGSDLVLETLRDLGVDTIFGYPGgavLPLYD--AIYNFEGIRHILARHEQGALHEAEGYAKSTGKLGVAVVTSG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 96 PGFLNGLTALANATTNCFPMILISGSSEREivDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRP 175
Cdd:PRK07282 83 PGATNAITGIADAMSDSVPLLVFTGQVARA--GIGKDAFQEADIVGITMPITKYNYQIRETADIPRIITEAVHIATTGRP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 176 GGVYLDLPAKLfsQVIDADLGARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESG 255
Cdd:PRK07282 161 GPVVIDLPKDV--SALETDFIYDPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVILAGGGINYAEAATELNAFAERYQ 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 256 IPYVPMSMAKGLLPDTHPLSAGA-------ARSTALKDSDVVLLVGARLNWLLShGKGKTWGEpgSKRFIQIDIEPREMD 328
Cdd:PRK07282 239 IPVVTTLLGQGTIATSHPLFLGMggmhgsyAANIAMTEADFMINIGSRFDDRLT-GNPKTFAK--NAKVAHIDIDPAEIG 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 329 SNVEIVAPVVGDIGSCVEALL--DGIRKDWkgapSNWLET-LRGKREANIAKMAPKLMKnssPMCFHSALGALrtvikER 405
Cdd:PRK07282 316 KIIKTDIPVVGDAKKALQMLLaePTVHNNT----EKWIEKvTKDKNRVRSYDKKERVVQ---PQAVIERIGEL-----TN 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 406 PDAILVNE-GANTLDLARgiidmYQP----RKRLDVGTWGVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETI 479
Cdd:PRK07282 384 GDAIVVTDvGQHQMWAAQ-----YYPyqneRQLVTSGGLGTMGFGIPAAIGAKIaNPDKEVILFVGDGGFQMTNQELAIL 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 480 CRYELPVCIVIFNNN--GIYRGTDTDPTGRDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVdEAMNSGKPTLIN 557
Cdd:PRK07282 459 NIYKVPIKVVMLNNHslGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAYGIKHYKFDNPETLAQDL-EVITEDVPMLIE 537
|
...
gi 2030910552 558 AEI 560
Cdd:PRK07282 538 VDI 540
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
21-548 |
5.66e-41 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 156.44 E-value: 5.66e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 21 PELTDGFHLVIDALKLNGIETIYNVPG---IPITDlgRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPG 97
Cdd:PRK06466 1 MELLSGAEMLVRALRDEGVEYIYGYPGgavLHIYD--ALFKQDKVEHILVRHEQAATHMADGYARATGKTGVVLVTSGPG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 98 FLNGLTALANATTNCFPMILISGSSEREIVdlqqGD--YEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRP 175
Cdd:PRK06466 79 ATNAITGIATAYMDSIPMVVLSGQVPSTLI----GEdaFQETDMVGISRPIVKHSFMVKHASEIPEIIKKAFYIAQSGRP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 176 GGVYLDLPAKLFSQVIDADLGARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESG 255
Cdd:PRK06466 155 GPVVVDIPKDMTNPAEKFEYEYPKKVKLRSYSPAVRGHSGQIRKAVEMLLAAKRPVIYSGGGVVLGNASALLTELAHLLN 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 256 IPYVPMSMAKGLLPDTHPLSAGA-------ARSTALKDSDVVLLVGARLNWLLSHGKGKTWgePGSKrFIQIDIEPREMD 328
Cdd:PRK06466 235 LPVTNTLMGLGGFPGTDRQFLGMlgmhgtyEANMAMHHADVILAVGARFDDRVTNGPAKFC--PNAK-IIHIDIDPASIS 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 329 SNVEIVAPVVGDIGSCVEALLDGIRKDW----KGAPSNWLETLRGKREANiaKMAPKLMKNSSPMCFHSALGALRTVIKE 404
Cdd:PRK06466 312 KTIKADIPIVGPVESVLTEMLAILKEIGekpdKEALAAWWKQIDEWRGRH--GLFPYDKGDGGIIKPQQVVETLYEVTNG 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 405 rpDAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETICRYE 483
Cdd:PRK06466 390 --DAYVTSDVGQHQMFAAQYYKFNKPNRWINSGGLGTMGFGLPAAMGVKLaFPDQDVACVTGEGSIQMNIQELSTCLQYG 467
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 484 LPVCIVIFNNN--GIYRG-TDTDPTGRDPGTTVfvkNSRYD--KMMEAFGGVGVNVTTPDELKRAVDEAM 548
Cdd:PRK06466 468 LPVKIINLNNGalGMVRQwQDMQYEGRHSHSYM---ESLPDfvKLAEAYGHVGIRITDLKDLKPKLEEAF 534
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
15-555 |
1.55e-39 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 152.55 E-value: 1.55e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 15 AMPHEEPELTDGFHLVIDALKLNGIETIYNVPG---IPITDlgRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICL 91
Cdd:PRK09107 2 AQKSHMPRQMTGAEMVVQALKDQGVEHIFGYPGgavLPIYD--EIFQQDDIQHILVRHEQGAGHAAEGYARSTGKPGVVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 92 TVSAPGFLNGLTALANATTNCFPMILISGSSEREIVdlqqGD--YEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRA 169
Cdd:PRK09107 80 VTSGPGATNAVTPLQDALMDSIPLVCITGQVPTHLI----GSdaFQECDTVGITRPCTKHNWLVKDVNDLARVIHEAFHV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 170 AVSGRPGGVYLDLPAKL-FS-------QVIDADLGARSLVKvidaapaqlPAPAAIARALDVLKSAERPLIILGKGA--A 239
Cdd:PRK09107 156 ATSGRPGPVVVDIPKDVqFAtgtytppQKAPVHVSYQPKVK---------GDAEAITEAVELLANAKRPVIYSGGGVinS 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 240 YAQADEAVRALVEESGIPYVPMSMAKGLLPDTHPLSAGA-------ARSTALKDSDVVLLVGARLNWLLShgkGKTWG-E 311
Cdd:PRK09107 227 GPEASRLLRELVELTGFPITSTLMGLGAYPASGKNWLGMlgmhgtyEANMAMHDCDVMLCVGARFDDRIT---GRLDAfS 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 312 PGSKRfIQIDIEPREMDSNVEIVAPVVGDIGSCVEALLDGIRKDWKGAPSNWLETLRGKREANIAKMAPKLMKNSSPMCF 391
Cdd:PRK09107 304 PNSKK-IHIDIDPSSINKNVRVDVPIIGDVGHVLEDMLRLWKARGKKPDKEALADWWGQIARWRARNSLAYTPSDDVIMP 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 392 HSALGALRTVIKERPDAILVNEGANTLDLARgIIDMYQPRKRLDVGTWGVMgiGMGFAVAAAVETGKP---VLAVEGDSA 468
Cdd:PRK09107 383 QYAIQRLYELTKGRDTYITTEVGQHQMWAAQ-FFGFEEPNRWMTSGGLGTM--GYGLPAALGVQIAHPdalVIDIAGDAS 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 469 FGFSGMEVETICRYELPVCIVIFNNN--GIYRG--------------TDTDPTgrdpgttvFVknsrydKMMEAFGGVGV 532
Cdd:PRK09107 460 IQMCIQEMSTAVQYNLPVKIFILNNQymGMVRQwqqllhgnrlshsyTEAMPD--------FV------KLAEAYGAVGI 525
|
570 580
....*....|....*....|...
gi 2030910552 533 NVTTPDELKRAVDEAMNSGKPTL 555
Cdd:PRK09107 526 RCEKPGDLDDAIQEMIDVDKPVI 548
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
219-348 |
3.94e-39 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 140.01 E-value: 3.94e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 219 RALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVPMSMAKGLLPDTHPLSAG-------AARSTALKDSDVVL 291
Cdd:pfam00205 3 KAAELLKKAKRPVILAGGGVRRSGASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLGmlgmhgtPAANEALEEADLVL 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2030910552 292 LVGARLNWLLSHGKGKTWgePGSKRFIQIDIEPREMDSNVEIVAPVVGDIGSCVEAL 348
Cdd:pfam00205 83 AVGARFDDIRTTGKLPEF--APDAKIIHIDIDPAEIGKNYPVDVPIVGDAKETLEAL 137
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
28-571 |
1.05e-38 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 150.15 E-value: 1.05e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 28 HLVIDALKLNGIETIYNVPGIPI---TDLGRLAQaEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTA 104
Cdd:PRK08611 8 EALVKLLQDWGIDHVYGIPGDSIdavVDALRKEQ-DKIKFIQVRHEEVAALAAAAYAKLTGKIGVCLSIGGPGAIHLLNG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 105 LANATTNCFPMILISGSSEREIVD---LQQGDYEEM-DQLAIAKPlckaafRVLHAADIGIGVARAIRAAVSGRpGGVYL 180
Cdd:PRK08611 87 LYDAKMDHVPVLALAGQVTSDLLGtdfFQEVNLEKMfEDVAVYNH------QIMSAENLPEIVNQAIRTAYEKK-GVAVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 181 DLPAKLFSQVIDADLGARSlvkVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQadEAVRALVEESGIPYVP 260
Cdd:PRK08611 160 TIPDDLPAQKIKDTTNKTV---DTFRPTVPSPKPKDIKKAAKLINKAKKPVILAGLGAKHAK--EELLAFAEKAKIPIIH 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 261 MSMAKGLLPDTHPLSAG-------AARSTALKDSDVVLLVGAR---LNWLlshgkgktwgePGSKRFIQIDIEPREMDSN 330
Cdd:PRK08611 235 TLPAKGIIPDDHPYSLGnlgkigtKPAYEAMQEADLLIMVGTNypyVDYL-----------PKKAKAIQIDTDPANIGKR 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 331 VEIVAPVVGDIGSCVEALLDGI-RKDWKGapsnWLETLRGKREANIAKMAPKLMKNSSPMCFHSALGALRTVIKErpDAI 409
Cdd:PRK08611 304 YPVNVGLVGDAKKALHQLTENIkHVEDRR----FLEACQENMAKWWKWMEEDENNASTPIKPERVMAAIQKIADD--DAV 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 410 L-VNEGANTLDLARgIIDMyQPRKRLDVGTW-GVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETICRYELPV 486
Cdd:PRK08611 378 LsVDVGTVTVWSAR-YLNL-GTNQKFIISSWlGTMGCGLPGAIAAKIaFPDRQAIAICGDGGFSMVMQDFVTAVKYKLPI 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 487 CIVIFNNNGI----YR---------GTDtdptgrdpgttvfVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKP 553
Cdd:PRK08611 456 VVVVLNNQQLafikYEqqaageleyAID-------------LSDMDYAKFAEACGGKGYRVEKAEELDPAFEEALAQDKP 522
|
570
....*....|....*...
gi 2030910552 554 TLINAEIDPAAGSESGNI 571
Cdd:PRK08611 523 VIIDVYVDPNAAPLPGKI 540
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
22-548 |
3.10e-38 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 148.85 E-value: 3.10e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 22 ELTDGFHLVIDALKLNGIETIYNVPGIPITDL-GRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLN 100
Cdd:PRK07979 2 EMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIyDALHTVGGIDHVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 101 GLTALANATTNCFPMILISGSSEREIVDLQQgdYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYL 180
Cdd:PRK07979 82 AITGIATAYMDSIPLVVLSGQVATSLIGYDA--FQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 181 DL------PAKLFSQVIDADLGARSLVKVIDaapaqlPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEES 254
Cdd:PRK07979 160 DLpkdilnPANKLPYVWPESVSMRSYNPTTQ------GHKGQIKRALQTLVAAKKPVVYVGGGAINAACHQQLKELVEKL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 255 GIPYVPMSMAKGLLPDTHPLSAGA-------ARSTALKDSDVVLLVGARLNWLLSHGKGKTWgePGSKrFIQIDIEPREM 327
Cdd:PRK07979 234 NLPVVSSLMGLGAFPATHRQSLGMlgmhgtyEANMTMHNADVIFAVGVRFDDRTTNNLAKYC--PNAT-VLHIDIDPTSI 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 328 DSNVEIVAPVVGDIGSCVEALLDGIRKDWKGAPSNWLETLRGKREANIAKMAPKLMKNSSPMCFHSALGALRTVIKErpD 407
Cdd:PRK07979 311 SKTVTADIPIVGDARQVLEQMLELLSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKG--D 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 408 AILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMgfAVAAAVETGKP---VLAVEGDSAFGFSGMEVETICRYEL 484
Cdd:PRK07979 389 AYVTSDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGL--PAALGVKMALPeetVVCVTGDGSIQMNIQELSTALQYEL 466
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2030910552 485 PVCIVIFNNNgiYRG-----TDTDPTGRDPGTTV-----FVknsrydKMMEAFGGVGVNVTTPDELKRAVDEAM 548
Cdd:PRK07979 467 PVLVLNLNNR--YLGmvkqwQDMIYSGRHSQSYMqslpdFV------RLAEAYGHVGIQISHPDELESKLSEAL 532
|
|
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
30-547 |
1.19e-37 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 147.05 E-value: 1.19e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 30 VIDALKLNGIETIYNVPGIPITDL-GRLAQAEGLRVISFRHEQNAGNAAAIagFLTKKPG---ICLTVSAPGFLNGLTAL 105
Cdd:PRK11269 10 AVLVLEKEGVTTAFGVPGAAINPFySAMRKHGGIRHILARHVEGASHMAEG--YTRATAGnigVCIGTSGPAGTDMITGL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 106 ANATTNCFPMILISGSSEREIvdLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLPAK 185
Cdd:PRK11269 88 YSASADSIPILCITGQAPRAR--LHKEDFQAVDIESIAKPVTKWAVTVREPALVPRVFQQAFHLMRSGRPGPVLIDLPFD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 186 LFSQVIDADLGARSLVKVidaaPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVPMSMAK 265
Cdd:PRK11269 166 VQVAEIEFDPDTYEPLPV----YKPAATRAQIEKALEMLNAAERPLIVAGGGVINADASDLLVEFAELTGVPVIPTLMGW 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 266 GLLPDTHPLSAGA---------ARSTALKdSDVVLLVGARlnWLLSH-GKGKTWgePGSKRFIQIDIEPREMDsnvEIVA 335
Cdd:PRK11269 242 GAIPDDHPLMAGMvglqtshryGNATLLA-SDFVLGIGNR--WANRHtGSVEVY--TKGRKFVHVDIEPTQIG---RVFG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 336 P---VVGDIGSCVEALLDgIRKDWKGA-----PSNWLETLRGKReaniAKMAPKLMKNSSPM-------CFHSALGalrt 400
Cdd:PRK11269 314 PdlgIVSDAKAALELLVE-VAREWKAAgrlpdRSAWVADCQERK----RTLLRKTHFDNVPIkpqrvyeEMNKAFG---- 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 401 vikerPDAILVnegaNTLDL----ARGIIDMYQPRKRLDVGTWGVMG--IGMGFAVAAAvETGKPVLAVEGDSAFGFSGM 474
Cdd:PRK11269 385 -----RDTCYV----STIGLsqiaAAQFLHVYKPRHWINCGQAGPLGwtIPAALGVRAA-DPDRNVVALSGDYDFQFLIE 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 475 EVETICRYELPVCIVIFNNN--GIYR----GTDTD-------PTGRDPGTTVF-VKNSrydKMMEAFGGVGVNVTTPDEL 540
Cdd:PRK11269 455 ELAVGAQFNLPYIHVLVNNAylGLIRqaqrAFDMDycvqlafENINSPELNGYgVDHV---KVAEGLGCKAIRVFKPEDI 531
|
....*..
gi 2030910552 541 KRAVDEA 547
Cdd:PRK11269 532 APALEQA 538
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
19-563 |
5.42e-36 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 142.21 E-value: 5.42e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 19 EEPELTDGFHLVIDALKLNGIETIYNVPG---IPITDlgRLAQAEGLRVISfRHEQNAGNAAAIAGFLTKKPGICLTVSA 95
Cdd:PRK07710 11 TEEKLMTGAQMLIEALEKEGVEVIFGYPGgavLPLYD--ALYDCGIPHILT-RHEQGAIHAAEGYARISGKPGVVIATSG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 96 PGFLNGLTALANATTNCFPMILISGSSEREIVDlqQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRP 175
Cdd:PRK07710 88 PGATNVVTGLADAMIDSLPLVVFTGQVATSVIG--SDAFQEADIMGITMPVTKHNYQVRKASDLPRIIKEAFHIATTGRP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 176 GGVYLDLPAKLfsQVIDADLGARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESG 255
Cdd:PRK07710 166 GPVLIDIPKDM--VVEEGEFCYDVQMDLPGYQPNYEPNLLQIRKLVQAVSVAKKPVILAGAGVLHAKASKELTSYAEQQE 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 256 IPYVPMSMAKGLLPDTHPLSAGAA-------RSTALKDSDVVLLVGARLNWLLShGKGKTWGEpgSKRFIQIDIEPREMD 328
Cdd:PRK07710 244 IPVVHTLLGLGGFPADHPLFLGMAgmhgtytANMALYECDLLINIGARFDDRVT-GNLAYFAK--EATVAHIDIDPAEIG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 329 SNVEIVAPVVGDIGSCVEALLDgiRKDWKGAPSNWLETLRGKREaniakmapklmknSSPMCFHSALGALR-----TVIK 403
Cdd:PRK07710 321 KNVPTEIPIVADAKQALQVLLQ--QEGKKENHHEWLSLLKNWKE-------------KYPLSYKRNSESIKpqkaiEMLY 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 404 E--RPDAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETIC 480
Cdd:PRK07710 386 EitKGEAIVTTDVGQHQMWAAQYYPFKTPDKWVTSGGLGTMGFGLPAAIGAQLaKPDETVVAIVGDGGFQMTLQELSVIK 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 481 RYELPVCIVIFNNN--GIYRGTDTDPTGRDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINA 558
Cdd:PRK07710 466 ELSLPVKVVILNNEalGMVRQWQEEFYNQRYSHSLLSCQPDFVKLAEAYGIKGVRIDDELEAKEQLQHAIELQEPVVIDC 545
|
....*
gi 2030910552 559 EIDPA 563
Cdd:PRK07710 546 RVLQS 550
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
26-547 |
5.52e-36 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 141.98 E-value: 5.52e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 26 GFHLVIDALKLNGIETIYNVPGIPITDL-GRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTA 104
Cdd:PRK06882 6 GAEMVVQSLRDEGVEYVFGYPGGSVLDIyDAIHTLGGIEHVLVRHEQAAVHMADGYARSTGKVGCVLVTSGPGATNAITG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 105 LANATTNCFPMILISGSSEREIVDLQQgdYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDL-- 182
Cdd:PRK06882 86 IATAYTDSVPLVILSGQVPSNLIGTDA--FQECDMLGISRPVVKHSFIVKNAEDIPSTIKKAFYIASTGRPGPVVIDIpk 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 183 ----PAKLFSQVIDADLGARSLVKVIDaapaqlPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPY 258
Cdd:PRK06882 164 dmvnPANKFTYEYPEEVSLRSYNPTVQ------GHKGQIKKALKALLVAKKPVLFVGGGVITAECSEQLTQFAQKLNLPV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 259 VPMSMAKGLLPDTHPLSAGA-------ARSTALKDSDVVLLVGARLNWLLSHGKGKTWgePGSKrFIQIDIEPREMDSNV 331
Cdd:PRK06882 238 TSSLMGLGAYPSTDKQFLGMlgmhgtyEANNAMHESDLILGIGVRFDDRTTNNLAKYC--PNAK-VIHIDIDPTSISKNV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 332 EIVAPVVGDIGSCVEALL-----DGIRKDWKGAPSNWLETLRGKreaniAKMAPKLMKNSSPMCFHSALGALRTVIKErp 406
Cdd:PRK06882 315 PAYIPIVGSAKNVLEEFLslleeENLAKSQTDLTAWWQQINEWK-----AKKCLEFDRTSDVIKPQQVVEAIYRLTNG-- 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 407 DAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMgiGMGFAVAAAVETGKP---VLAVEGDSAFGFSGMEVETICRYE 483
Cdd:PRK06882 388 DAYVASDVGQHQMFAALHYPFDKPRRWINSGGAGTM--GFGLPAAIGVKFAHPeatVVCVTGDGSIQMNIQELSTAKQYD 465
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2030910552 484 LPVCIVIFNNN---GIYRGTDTDPTGRDPGTTVfvkNSRYD--KMMEAFGGVGVNVTTPDELKRAVDEA 547
Cdd:PRK06882 466 IPVVIVSLNNRflgMVKQWQDLIYSGRHSQVYM---NSLPDfaKLAEAYGHVGIQIDTPDELEEKLTQA 531
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
12-547 |
6.37e-36 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 142.25 E-value: 6.37e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 12 TAGAMPHEEPELTdGFHLVIDALKLNGIETIYNVPG---IPITDlgRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPG 88
Cdd:PRK06965 10 TAESLSPPAADSI-GAEILMKALAAEGVEFIWGYPGgavLYIYD--ELYKQDKIQHVLVRHEQAAVHAADGYARATGKVG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 89 ICLTVSAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQgdYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIR 168
Cdd:PRK06965 87 VALVTSGPGVTNAVTGIATAYMDSIPMVVISGQVPTAAIGQDA--FQECDTVGITRPIVKHNFLVKDVRDLAETVKKAFY 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 169 AAVSGRPGGVYLDLP------AKLFSQVIDADLGARSLVKvidaapaqLPAPAAIARALDVLKSAERPLIILGKGAAYAQ 242
Cdd:PRK06965 165 IARTGRPGPVVVDIPkdvsktPCEYEYPKSVEMRSYNPVT--------KGHSGQIRKAVSLLLSAKRPYIYTGGGVILAN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 243 ADEAVRALVEESGIPYVPMSMAKGLLPDTHPLSAGA-------ARSTALKDSDVVLLVGARLNwllshgkGKTWGEPG-- 313
Cdd:PRK06965 237 ASRELRQLADLLGYPVTNTLMGLGAYPASDKKFLGMlgmhgtyEANMAMQHCDVLIAIGARFD-------DRVIGNPAhf 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 314 ---SKRFIQIDIEPREMDSNVEIVAPVVGDIGSCVEALLDGIR----KDWKGAPSNWLETLRGKREANIAK--MAPKLMK 384
Cdd:PRK06965 310 asrPRKIIHIDIDPSSISKRVKVDIPIVGDVKEVLKELIEQLQtaehGPDADALAQWWKQIEGWRSRDCLKydRESEIIK 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 385 nssPMCFHSALGALRTVikerpDAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMGFAVaaAVETGKP---VL 461
Cdd:PRK06965 390 ---PQYVVEKLWELTDG-----DAFVCSDVGQHQMWAAQFYRFNEPRRWINSGGLGTMGVGLPYAM--GIKMAHPdddVV 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 462 AVEGDSAFGFSGMEVETICRYELPVCIVIFNNN--GIYRG-TDTDPTGRDPGTTV-----FVknsrydKMMEAFGGVGVN 533
Cdd:PRK06965 460 CITGEGSIQMCIQELSTCLQYDTPVKIISLNNRylGMVRQwQEIEYSKRYSHSYMdalpdFV------KLAEAYGHVGMR 533
|
570
....*....|....
gi 2030910552 534 VTTPDELKRAVDEA 547
Cdd:PRK06965 534 IEKTSDVEPALREA 547
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
29-562 |
2.08e-35 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 139.96 E-value: 2.08e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 29 LVIDALKLNGIETIYNVPGIPITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTALANA 108
Cdd:PRK06457 7 VIIRVLEDNGIQRIYGIPGDSIDPLVDAIRKSKVKYVQVRHEEGAALAASVEAKITGKPSACMGTSGPGSIHLLNGLYDA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 109 TTNCFPMILISGSSEreiVDLQQGDY-EEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRpGGVYLDLPAKLF 187
Cdd:PRK06457 87 KMDHAPVIALTGQVE---SDMIGHDYfQEVNLTKLFDDVAVFNQILINPENAEYIIRRAIREAISKR-GVAHINLPVDIL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 188 SQVIDADLGARSLVKVIDaapaqlpAPAAIARALDVLKSAERPLIILGKGAayAQADEAVRALVEESGIPYVPMSMAKGL 267
Cdd:PRK06457 163 RKSSEYKGSKNTEVGKVK-------YSIDFSRAKELIKESEKPVLLIGGGT--RGLGKEINRFAEKIGAPIIYTLNGKGI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 268 LPDTHPLSAGA-------ARSTALKDSDVVLLVGARL---NWLlshgkgktwgePGSKRFIQIDIEPREMDSNVEIVAPV 337
Cdd:PRK06457 234 LPDLDPKVMGGigllgtkPSIEAMDKADLLIMLGTSFpyvNFL-----------NKSAKVIQVDIDNSNIGKRLDVDLSY 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 338 VGDIGscveallDGIRKDWKGAPSNWLETLRGKREANIAKMAPKLMKNSSPMcfhsALGALRTVIKER--PDAILVNEGA 415
Cdd:PRK06457 303 PIPVA-------EFLNIDIEEKSDKFYEELKGKKEDWLDSISKQENSLDKPM----KPQRVAYIVSQKckKDAVIVTDTG 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 416 N-TLDLARGIidMYQPRKRLDVGTW-GVMGIGMGFAVAA--AVETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIF 491
Cdd:PRK06457 372 NvTMWTARHF--RASGEQTFIFSAWlGSMGIGVPGSVGAsfAVENKRQVISFVGDGGFTMTMMELITAKKYDLPVKIIIY 449
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2030910552 492 NNNGIYRGTDTDPTGRDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEIDP 562
Cdd:PRK06457 450 NNSKLGMIKFEQEVMGYPEWGVDLYNPDFTKIAESIGFKGFRLEEPKEAEEIIEEFLNTKGPAVLDAIVDP 520
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
28-549 |
2.52e-35 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 140.14 E-value: 2.52e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 28 HLVIDALKLNGIETIYNVPGipiTDLGRL------AQAEGLRVISF---RHEQNAGNAAAIAGFLTKKPGICLTVSAPGF 98
Cdd:PRK08327 11 ELFLELLKELGVDYIFINSG---TDYPPIieakarARAAGRPLPEFvicPHEIVAISMAHGYALVTGKPQAVMVHVDVGT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 99 LNGLTALANATTNCFPMILISGSSEReivdLQQGDY-----------EEMDQLAIAKPLCKAAFRVLHAADIGIGVARAI 167
Cdd:PRK08327 88 ANALGGVHNAARSRIPVLVFAGRSPY----TEEGELgsrntrihwtqEMRDQGGLVREYVKWDYEIRRGDQIGEVVARAI 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 168 RAAVSGRPGGVYLDLPAK-LFSQVIDADLGARSLVKVidaaPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEA 246
Cdd:PRK08327 164 QIAMSEPKGPVYLTLPREvLAEEVPEVKADAGRQMAP----APPAPDPEDIARAAEMLAAAERPVIITWRAGRTAEGFAS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 247 VRALVEESGIP---YVPMSMAkglLPDTHPLSAGAARSTALKDSDVVLLVGARLNWLLSHGKgktwgEPGSKRFIQIDIE 323
Cdd:PRK08327 240 LRRLAEELAIPvveYAGEVVN---YPSDHPLHLGPDPRADLAEADLVLVVDSDVPWIPKKIR-----PDADARVIQIDVD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 324 P-------REMDSNVEIVApvvgDIGSCVEALLDGIRKDWKGAP----SNWLETLRGKREANIAKM-APKLMKNSSPMcf 391
Cdd:PRK08327 312 PlksriplWGFPCDLCIQA----DTSTALDQLEERLKSLASAERrrarRRRAAVRELRIRQEAAKRaEIERLKDRGPI-- 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 392 HSA-LGA-LRTVIkeRPDAILVNEGANTLDLARgiidMYQPRKRLDVGTWGVMGIGMGFAVAAAVETG-KPVLAVEGDSA 468
Cdd:PRK08327 386 TPAyLSYcLGEVA--DEYDAIVTEYPFVPRQAR----LNKPGSYFGDGSAGGLGWALGAALGAKLATPdRLVIATVGDGS 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 469 FGFSgmeVETIC-----RYELPVCIVIFNNNG---IYRGTD-TDPTG-----RDPGTTVFVKNSRYDKMMEAFGGVGVNV 534
Cdd:PRK08327 460 FIFG---VPEAAhwvaeRYGLPVLVVVFNNGGwlaVKEAVLeVYPEGyaarkGTFPGTDFDPRPDFAKIAEAFGGYGERV 536
|
570
....*....|....*
gi 2030910552 535 TTPDELKRAVDEAMN 549
Cdd:PRK08327 537 EDPEELKGALRRALA 551
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
28-576 |
1.84e-34 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 137.43 E-value: 1.84e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 28 HLVIDALKLNGIETIYNVPGI---PITDlgRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTA 104
Cdd:PRK07064 7 ELIAAFLEQCGVKTAFGVISIhnmPILD--AIGRRGKIRFVPARGEAGAVNMADAHARVSGGLGVALTSTGTGAGNAAGA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 105 LANATTNCFPMILISGSSEREIVDLQQGDYEEM-DQLAIAKPLCKAAFRVlHAADIGIGVAR-AIRAAVSGRPGGVYLDL 182
Cdd:PRK07064 85 LVEALTAGTPLLHITGQIETPYLDQDLGYIHEApDQLTMLRAVSKAAFRV-RSAETALATIReAVRVALTAPTGPVSVEI 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 183 PAKLFSQVIDADLGARSLvkvidAAPAQLPAPAAIARALDVLKSAERPLIILGKGAayAQADEAVRALVeESGIPYVPMS 262
Cdd:PRK07064 164 PIDIQAAEIELPDDLAPV-----HVAVPEPDAAAVAELAERLAAARRPLLWLGGGA--RHAGAEVKRLV-DLGFGVVTST 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 263 MAKGLLPDTHPLSAGAARSTA-----LKDSDVVLLVGARLNwllSHgKGKTWGEPGSKRFIQIDIEPREMDSNVEIVAPV 337
Cdd:PRK07064 236 QGRGVVPEDHPASLGAFNNSAavealYKTCDLLLVVGSRLR---GN-ETLKYSLALPRPLIRVDADAAADGRGYPNDLFV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 338 VGDIGSCVEALLDGIRKDWKGAPsNWLETLRGKREANIAkmapKLMKNSSPmcfHSAL-GALRTVIKErpDAILVNE--G 414
Cdd:PRK07064 312 HGDAARVLARLADRLEGRLSVDP-AFAADLRAAREAAVA----DLRKGLGP---YAKLvDALRAALPR--DGNWVRDvtI 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 415 ANTLDLARgIIDMYQPRKRL-DVGtwGVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIFN 492
Cdd:PRK07064 382 SNSTWGNR-LLPIFEPRANVhALG--GGIGQGLAMAIGAALaGPGRKTVGLVGDGGLMLNLGELATAVQENANMVIVLMN 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 493 NN--GIYRG-TDTDPTGRDPGTTVFVKNsrYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLInaEIDPAAgsesg 569
Cdd:PRK07064 459 DGgyGVIRNiQDAQYGGRRYYVELHTPD--FALLAASLGLPHWRVTSADDFEAVLREALAKEGPVLV--EVDMLS----- 529
|
....*..
gi 2030910552 570 nIGSLNP 576
Cdd:PRK07064 530 -IGPFAA 535
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
26-564 |
1.13e-32 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 131.93 E-value: 1.13e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 26 GFHLVIDALKLNGIETIYNVPG---IPITDlgRLAQAeGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGL 102
Cdd:PRK08978 3 GAQWVVHALRAQGVDTVFGYPGgaiMPVYD--ALYDG-GVEHLLCRHEQGAAMAAIGYARATGKVGVCIATSGPGATNLI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 103 TALANATTNCFPMILISGSSEREIV--DLQQgdyeEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYL 180
Cdd:PRK08978 80 TGLADALLDSVPVVAITGQVSSPLIgtDAFQ----EIDVLGLSLACTKHSFLVQSLEELPEIMAEAFEIASSGRPGPVLV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 181 DLPAKLfsQVIDADLgaRSLVKVIDAAPAQLPAPAAIARALdvLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVp 260
Cdd:PRK08978 156 DIPKDI--QLAEGEL--EPHLTTVENEPAFPAAELEQARAL--LAQAKKPVLYVGGGVGMAGAVPALREFLAATGMPAV- 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 261 mSMAKGL--LPDTHPLSAG-------AARSTALKDSDVVLLVGAR--------LNWLLSHGKgktwgepgskrFIQIDIE 323
Cdd:PRK08978 229 -ATLKGLgaVEADHPYYLGmlgmhgtKAANLAVQECDLLIAVGARfddrvtgkLNTFAPHAK-----------VIHLDID 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 324 PREMDSNVEIVAPVVGDIGSCVEAL---LDgirkdwkgaPSNWLETLRGKREANIAK--------MAPKLmknsspmcfh 392
Cdd:PRK08978 297 PAEINKLRQAHVALQGDLNALLPALqqpLN---------IDAWRQHCAQLRAEHAWRydhpgeaiYAPAL---------- 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 393 salgaLRTVIKERPDAILVneganTLDLarGIIDMY--------QPRKRLDVGTWGVMGIGMGFAVAAAVetGKP---VL 461
Cdd:PRK08978 358 -----LKQLSDRKPADTVV-----TTDV--GQHQMWvaqhmrftRPENFITSSGLGTMGFGLPAAIGAQV--ARPddtVI 423
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 462 AVEGDSAFGFSGMEVETICRYELPVCIVIFNN--------------NGIYRGTDTDptgrdpgttvfvKNSRYDKMMEAF 527
Cdd:PRK08978 424 CVSGDGSFMMNVQELGTIKRKQLPVKIVLLDNqrlgmvrqwqqlffDERYSETDLS------------DNPDFVMLASAF 491
|
570 580 590
....*....|....*....|....*....|....*..
gi 2030910552 528 GGVGVNVTTPDELKRAVDEAMNSGKPTLINAEIDPAA 564
Cdd:PRK08978 492 GIPGQTITRKDQVEAALDTLLNSEGPYLLHVSIDELE 528
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
406-560 |
2.28e-29 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 113.89 E-value: 2.28e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 406 PDAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMGFAVAAAVET-GKPVLAVEGDSAFGFSGMEVETICRYEL 484
Cdd:cd00568 12 EDAIVVNDAGNSAYWAYRYLPLRRGRRFLTSTGFGAMGYGLPAAIGAALAApDRPVVCIAGDGGFMMTGQELATAVRYGL 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2030910552 485 PVCIVIFNNNGiYRGTDTDPTGRDPGTTVFVKNSRYD--KMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEI 560
Cdd:cd00568 92 PVIVVVFNNGG-YGTIRMHQEAFYGGRVSGTDLSNPDfaALAEAYGAKGVRVEDPEDLEAALAEALAAGGPALIEVKT 168
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
26-493 |
1.95e-28 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 119.84 E-value: 1.95e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 26 GFHLVIDALKLNGIETIYNVPGIPITDLGR-LAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTA 104
Cdd:PLN02470 15 GADILVEALEREGVDTVFAYPGGASMEIHQaLTRSNCIRNVLCRHEQGEVFAAEGYAKASGKVGVCIATSGPGATNLVTG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 105 LANATTNCFPMILISGSSEREIVDLQQgdYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLPA 184
Cdd:PLN02470 95 LADALLDSVPLVAITGQVPRRMIGTDA--FQETPIVEVTRSITKHNYLVMDVEDIPRVIREAFFLASSGRPGPVLVDIPK 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 185 KLFSQVIDADLGARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAayAQADEAVRALVEESGIPYVPMSMA 264
Cdd:PLN02470 173 DIQQQLAVPNWNQPMKLPGYLSRLPKPPEKSQLEQIVRLISESKRPVVYVGGGC--LNSSEELREFVELTGIPVASTLMG 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 265 KGLLPDTHPLSA------GAARST-ALKDSDVVLLVGARLNWLLShgkGKTWGEPGSKRFIQIDIEPREMDSNVEIVAPV 337
Cdd:PLN02470 251 LGAFPASDELSLqmlgmhGTVYANyAVDSADLLLAFGVRFDDRVT---GKLEAFASRASIVHIDIDPAEIGKNKQPHVSV 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 338 VGDIGSCVEALLDGIRKDWKGAP--SNWLETLRGKREANiakmapklmknssPMCFhsalgalrtviKERPDAILVNEGA 415
Cdd:PLN02470 328 CADVKLALQGLNKLLEERKAKRPdfSAWRAELDEQKEKF-------------PLSY-----------PTFGDAIPPQYAI 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 416 NTLD-LARG--II-------DMY--------QPRKRLDVGTWGVMGIGMGFAVAAAVET-GKPVLAVEGDSAFGFSGMEV 476
Cdd:PLN02470 384 QVLDeLTDGnaIIstgvgqhQMWaaqwykykEPRRWLTSGGLGAMGFGLPAAIGAAAANpDAIVVDIDGDGSFIMNIQEL 463
|
490
....*....|....*..
gi 2030910552 477 ETICRYELPVCIVIFNN 493
Cdd:PLN02470 464 ATIHVENLPVKIMVLNN 480
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
414-558 |
2.91e-28 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 110.37 E-value: 2.91e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 414 GANTLDLARgIIDMYQPRKRLDVGTWGVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIFN 492
Cdd:pfam02775 3 GCHQMWAAQ-YYRFRPPRRYLTSGGLGTMGYGLPAAIGAKLaRPDRPVVAIAGDGGFQMNLQELATAVRYNLPITVVVLN 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2030910552 493 NNG----------IYRGTDTDPTGRDPgttvfvKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINA 558
Cdd:pfam02775 82 NGGygmtrgqqtpFGGGRYSGPSGKIL------PPVDFAKLAEAYGAKGARVESPEELEEALKEALEHDGPALIDV 151
|
|
| PRK07092 |
PRK07092 |
benzoylformate decarboxylase; Reviewed |
94-561 |
3.28e-28 |
|
benzoylformate decarboxylase; Reviewed
Pssm-ID: 235931 [Multi-domain] Cd Length: 530 Bit Score: 118.52 E-value: 3.28e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 94 SAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEmDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSG 173
Cdd:PRK07092 81 SAAGVGNAMGNLFTAFKNHTPLVITAGQQARSILPFEPFLAAV-QAAELPKPYVKWSIEPARAEDVPAAIARAYHIAMQP 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 174 RPGGVYLDLPAKLFSQVIDaDLGARSLVKVIdaapaqLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEE 253
Cdd:PRK07092 160 PRGPVFVSIPYDDWDQPAE-PLPARTVSSAV------RPDPAALARLGDALDAARRPALVVGPAVDRAGAWDDAVRLAER 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 254 SGIP-YV-PMSmAKGLLPDTHPLSAG---AAR---STALKDSDVVLLVGARLNWLLSHGKGKTWgePGSKRFIQIdIEpr 325
Cdd:PRK07092 233 HRAPvWVaPMS-GRCSFPEDHPLFAGflpASRekiSALLDGHDLVLVIGAPVFTYHVEGPGPHL--PEGAELVQL-TD-- 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 326 emDSNVEIVAPV----VGDIGSCVEALLDGIRKDWKGAPSnwletlrgKREaniakMAPKLMKNSSPMcfhSALGALRTV 401
Cdd:PRK07092 307 --DPGEAAWAPMgdaiVGDIRLALRDLLALLPPSARPAPP--------ARP-----MPPPAPAPGEPL---SVAFVLQTL 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 402 IKERP-DAILVNEGANTldlaRGIIDMYQPRKRldVGTWGVMGI-GMGFAVAAAV-----ETGKPVLAVEGDSAFGFSGM 474
Cdd:PRK07092 369 AALRPaDAIVVEEAPST----RPAMQEHLPMRR--QGSFYTMASgGLGYGLPAAVgvalaQPGRRVIGLIGDGSAMYSIQ 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 475 EVETICRYELPVCIVIFNNNGIYRGTDTDPT---GRDPGTTV----FVknsrydKMMEAFGGVGVNVTTPDELKRAVDEA 547
Cdd:PRK07092 443 ALWSAAQLKLPVTFVILNNGRYGALRWFAPVfgvRDVPGLDLpgldFV------ALARGYGCEAVRVSDAAELADALARA 516
|
490
....*....|....
gi 2030910552 548 MNSGKPTLINAEID 561
Cdd:PRK07092 517 LAADGPVLVEVEVA 530
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
114-562 |
1.37e-27 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 116.80 E-value: 1.37e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 114 PMILISGSSEREIVD--------LQQGDYEemDQLAIAKPLCKAAfRVLHAADIGIGVARAIRAAVS-GRPggVYLDLPA 184
Cdd:COG3961 95 PVVHIVGAPGTRAQRrgpllhhtLGDGDFD--HFLRMFEEVTVAQ-AVLTPENAAAEIDRVLAAALReKRP--VYIELPR 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 185 KLFSQVIDADLGARSLVkviDAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVPMSMA 264
Cdd:COG3961 170 DVADAPIEPPEAPLPLP---PPASDPAALAAAVAAAAERLAKAKRPVILAGVEVHRFGLQEELLALAEKTGIPVATTLLG 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 265 KGLLPDTHPLS----AGAARSTALKD----SDVVLLVGARLN-WLLShgkGKTWGEPGSKrfiQIDIEPREMDSNVEIVA 335
Cdd:COG3961 247 KSVLDESHPQFigtyAGAASSPEVREyvenADCVLCLGVVFTdTNTG---GFTAQLDPER---TIDIQPDSVRVGGHIYP 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 336 PVvgDIGSCVEALLDGIRKdwkgapsnwletLRGKREANIAKMAPKLMKNSSPMCFHSALGALRTVIkeRPDAILVNE-- 413
Cdd:COG3961 321 GV--SLADFLEALAELLKK------------RSAPLPAPAPPPPPPPAAPDAPLTQDRLWQRLQAFL--DPGDIVVADtg 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 414 ----GANTLDLARGIIDMYQPrkrldvgTWGvmgiGMGFAVAAA--VETGKP---VLAVEGDSAFGFSGMEVETICRYEL 484
Cdd:COG3961 385 tslfGAADLRLPEGATFIAQP-------LWG----SIGYTLPAAlgAALAAPdrrVILLVGDGAFQLTAQELSTMLRYGL 453
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 485 PVCIVIFNNNG------IYrgtdtDPTGR--DpgttvfVKNSRYDKMMEAFGG---VGVNVTTPDELKRAVDEAM-NSGK 552
Cdd:COG3961 454 KPIIFVLNNDGytieraIH-----GPDGPynD------IANWDYAKLPEAFGGgnaLGFRVTTEGELEEALAAAEaNTDR 522
|
490
....*....|
gi 2030910552 553 PTLINAEIDP 562
Cdd:COG3961 523 LTLIEVVLDK 532
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
387-565 |
1.71e-22 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 95.27 E-value: 1.71e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 387 SPMCFHSALGALRTVIKErpDAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMGFAVAA-AVETGKPVLAVEG 465
Cdd:cd02013 2 NPMHPRQVLRELEKAMPE--DAIVSTDIGNICSVANSYLRFEKPRSFIAPLSFGNCGYALPAIIGAkAAAPDRPVVAIAG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 466 DSAFGFSGMEVETICRYELPVCIVIFNNN--GIYRGTDTDPTGRDpgttvFV----KNSRYDKMMEAFGGVGVNVTTPDE 539
Cdd:cd02013 80 DGAWGMSMMEIMTAVRHKLPVTAVVFRNRqwGAEKKNQVDFYNNR-----FVgtelESESFAKIAEACGAKGITVDKPED 154
|
170 180
....*....|....*....|....*....
gi 2030910552 540 LKRAVDEA---MNSGKPTLINAEIDPAAG 565
Cdd:cd02013 155 VGPALQKAiamMAEGKTTVIEIVCDQELG 183
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
406-564 |
1.37e-20 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 89.51 E-value: 1.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 406 PDAIL-VNEGANTLDLARGIiDMYQPRKRLDVGTWGVMGIGMGFAVAA-AVETGKPVLAVEGDSAFGFSGMEVETICRYE 483
Cdd:cd02014 17 DDAIFtIDVGNVTVWAARHL-RMNGKQRFILSGLLATMGNGLPGAIAAkLAYPDRQVIALSGDGGFAMLMGDLITAVKYN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 484 LPVCIVIFNNNGIYRGTDTDPTGRDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEIDPA 563
Cdd:cd02014 96 LPVIVVVFNNSDLGFIKWEQEVMGQPEFGVDLPNPDFAKIAEAMGIKGIRVEDPDELEAALDEALAADGPVVIDVVTDPN 175
|
.
gi 2030910552 564 A 564
Cdd:cd02014 176 E 176
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
425-564 |
7.95e-20 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 87.55 E-value: 7.95e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 425 IDMYQPRKRLDVGTWGVMGIGMGFAVAAAV-ETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIFNNN--GIYRGTD 501
Cdd:cd02015 35 YRFKKPRSWLTSGGLGTMGFGLPAAIGAKVaRPDKTVICIDGDGSFQMNIQELATAAQYNLPVKIVILNNGslGMVRQWQ 114
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2030910552 502 TDPTGRDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEIDPAA 564
Cdd:cd02015 115 ELFYEGRYSHTTLDSNPDFVKLAEAYGIKGLRVEKPEELEAALKEALASDGPVLLDVLVDPEE 177
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
397-560 |
5.57e-19 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 84.57 E-value: 5.57e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 397 ALRTVIKErpDAILVNEGANTLDLARGIIDMYQPrkrldvGTW-----GVMGIGMGFAVAAAVET-GKPVLAVEGDSAFG 470
Cdd:cd02002 9 ALAAALPE--DAIIVDEAVTNGLPLRDQLPLTRP------GSYftlrgGGLGWGLPAAVGAALANpDRKVVAIIGDGSFM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 471 FSGMEVETICRYELPVCIVIFNNNGiYR---------GTDTDPTGRDPGTTVFVKNSRYDKMMEAFGGVGVNVTTPDELK 541
Cdd:cd02002 81 YTIQALWTAARYGLPVTVVILNNRG-YGalrsflkrvGPEGPGENAPDGLDLLDPGIDFAAIAKAFGVEAERVETPEELD 159
|
170
....*....|....*....
gi 2030910552 542 RAVDEAMNSGKPTLINAEI 560
Cdd:cd02002 160 EALREALAEGGPALIEVVV 178
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
38-563 |
1.47e-16 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 83.04 E-value: 1.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 38 GIETIYNVPGIPITDL-GRLAQAEG-LRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTALANATTNCFPM 115
Cdd:PRK08273 17 GVRRVFGYPGDGINGLlGALGRADDkPEFVQARHEEMAAFMAVAHAKFTGEVGVCLATSGPGAIHLLNGLYDAKLDHVPV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 116 ILISGSSEREI--------VDLQQ------GDYEEMdqlaiakplCKAAFRVLHAADigigvaRAIRAAVSGR-PGGVYL 180
Cdd:PRK08273 97 VAIVGQQARAAlgghyqqeVDLQSlfkdvaGAFVQM---------VTVPEQLRHLVD------RAVRTALAERtVTAVIL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 181 --DL-------PAKLFSQVIDAdLGARSLVKVIDAAPAQlpapaaiaRALDVLKSAERPLIILGKGAayAQADEAVRALV 251
Cdd:PRK08273 162 pnDVqeleyepPPHAHGTVHSG-VGYTRPRVVPYDEDLR--------RAAEVLNAGRKVAILVGAGA--LGATDEVIAVA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 252 EESGIPYVPMSMAKGLLPDTHPLSAGA-------ARSTALKDSDVVLLVGARLNWllshgkGKTWGEPGSKRFIQIDIEP 324
Cdd:PRK08273 231 ERLGAGVAKALLGKAALPDDLPWVTGSigllgtkPSYELMRECDTLLMVGSSFPY------SEFLPKEGQARGVQIDIDG 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 325 REMDSNVEIVAPVVGDIGSCVEALL--------DGIRKDWKGAPSNWLETLRGKREANIAKMAPKLMknsspmcFHsalg 396
Cdd:PRK08273 305 RMLGLRYPMEVNLVGDAAETLRALLpllerkkdRSWRERIEKWVARWWETLEARAMVPADPVNPQRV-------FW---- 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 397 ALRTVIKErpDAIL-------VNEGANTLDLARGIidmyqpRKRLDvGTWGVMGIGMGFAVAAA-VETGKPVLAVEGDSA 468
Cdd:PRK08273 374 ELSPRLPD--NAILtadsgscANWYARDLRMRRGM------MASLS-GTLATMGPAVPYAIAAKfAHPDRPVIALVGDGA 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 469 FGFSGM-EVETICRY-----ELPVCIVIFNNNGI------YRGTDTDPTGRDPGTTVFVKNSRYDKMMeafGGVGVNVTT 536
Cdd:PRK08273 445 MQMNGMaELITVAKYwrqwsDPRLIVLVLNNRDLnqvtweQRVMEGDPKFEASQDLPDVPYARFAELL---GLKGIRVDD 521
|
570 580
....*....|....*....|....*..
gi 2030910552 537 PDELKRAVDEAMNSGKPTLINAEIDPA 563
Cdd:PRK08273 522 PEQLGAAWDEALAADRPVVLEVKTDPN 548
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
442-561 |
2.12e-14 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 71.55 E-value: 2.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 442 MGIGMGFAVAAA-VETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIFNNN--GIYRGTDTDPTGRDPGTTvfVKNS 518
Cdd:cd02010 50 MGVALPGAIGAKlVYPDRKVVAVSGDGGFMMNSQELETAVRLKIPLVVLIWNDNgyGLIKWKQEKEYGRDSGVD--FGNP 127
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2030910552 519 RYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEID 561
Cdd:cd02010 128 DFVKYAESFGAKGYRIESADDLLPVLERALAADGVHVIDCPVD 170
|
|
| TPP_PYR_POX |
cd07039 |
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) ... |
29-189 |
1.89e-13 |
|
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Lactobacillus plantarum POX is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate.
Pssm-ID: 132922 [Multi-domain] Cd Length: 164 Bit Score: 68.35 E-value: 1.89e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 29 LVIDALKLNGIETIYNVPGIPITDL-GRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTALAN 107
Cdd:cd07039 5 VIVETLENWGVKRVYGIPGDSINGLmDALRREGKIEFIQVRHEEAAAFAASAEAKLTGKLGVCLGSSGPGAIHLLNGLYD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 108 ATTNCFPMILISGSSEREIV--DLQQgdyeEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRpgGV-YLDLPA 184
Cdd:cd07039 85 AKRDRAPVLAIAGQVPTDELgtDYFQ----EVDLLALFKDVAVYNETVTSPEQLPELLDRAIRTAIAKR--GVaVLILPG 158
|
....*
gi 2030910552 185 KLFSQ 189
Cdd:cd07039 159 DVQDA 163
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
31-566 |
2.14e-12 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 69.63 E-value: 2.14e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 31 IDALKLNGIETIYNVPGI---PITDLGRlaQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTALAN 107
Cdd:PRK06546 10 VEQLVAAGVKRIYGIVGDslnPIVDAVR--RTGGIEWVHVRHEEAAAFAAAAEAQLTGKLAVCAGSCGPGNLHLINGLYD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 108 ATTNCFPMILIS--------GSS-------EREIVDLQqgDYEEMDQLAIAKPlckaafRVLHAAdigigvaraIRAAVs 172
Cdd:PRK06546 88 AHRSGAPVLAIAshipsaqiGSGffqethpDRLFVECS--GYCEMVSSAEQAP------RVLHSA---------IQHAV- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 173 GRPGGVYLDLPAklfsQVIDADLGARSLVKVIDAAPAQLPAPAAIARAL-DVLKSAERPLIILGKGAAYAQADeaVRALV 251
Cdd:PRK06546 150 AGGGVSVVTLPG----DIADEPAPEGFAPSVISPRRPTVVPDPAEVRALaDAINEAKKVTLFAGAGVRGAHAE--VLALA 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 252 EESGIPY-----------------VPMSmakGLLpdthplSAGAARStALKDSDVVLLVGARL---NWLlshgkgktwge 311
Cdd:PRK06546 224 EKIKAPVghslrgkewiqydnpfdVGMS---GLL------GYGAAHE-AMHEADLLILLGTDFpydQFL----------- 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 312 PGsKRFIQIDIEPREMDSNVEIVAPVVGDIGSCVEALLDGIRKdwkgapsnwlETLRGKREANIAKMAPKLmknsspmcf 391
Cdd:PRK06546 283 PD-VRTAQVDIDPEHLGRRTRVDLAVHGDVAETIRALLPLVKE----------KTDRRFLDRMLKKHARKL--------- 342
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 392 HSALGAL-RTVIKERP----------------DAIL-VNEGANTLDLARGIidMYQPRKRLdVGTW--GVMGIGMGFAV- 450
Cdd:PRK06546 343 EKVVGAYtRKVEKHTPihpeyvasildelaadDAVFtVDTGMCNVWAARYI--TPNGRRRV-IGSFrhGSMANALPHAIg 419
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 451 AAAVETGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIFNNN--GIYR-----------GTDtdptgrdpgttvfVKN 517
Cdd:PRK06546 420 AQLADPGRQVISMSGDGGLSMLLGELLTVKLYDLPVKVVVFNNStlGMVKlemlvdglpdfGTD-------------HPP 486
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 2030910552 518 SRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEIDPAAGS 566
Cdd:PRK06546 487 VDYAAIAAALGIHAVRVEDPKDVRGALREAFAHPGPALVDVVTDPNALS 535
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
405-562 |
2.21e-12 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 65.63 E-value: 2.21e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 405 RPDAILVNE------GANTLDL---ARGIIDMYqprkrldvgtWGVMGIGMG--FAVAAAVETGKPVLaVEGDSAFGFSG 473
Cdd:cd02005 16 KPNDILVAEtgtswfGALDLKLpkgTRFISQPL----------WGSIGYSVPaaLGAALAAPDRRVIL-LVGDGSFQMTV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 474 MEVETICRYELPVCIVIFNNNG------IYRGTDT--DptgrdpgttvfVKNSRYDKMMEAFG----GVGVNVTTPDELK 541
Cdd:cd02005 85 QELSTMIRYGLNPIIFLINNDGytieraIHGPEASynD-----------IANWNYTKLPEVFGggggGLSFRVKTEGELD 153
|
170 180
....*....|....*....|..
gi 2030910552 542 RAVDEAM-NSGKPTLINAEIDP 562
Cdd:cd02005 154 EALKDALfNRDKLSLIEVILPK 175
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
26-560 |
9.27e-11 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 64.51 E-value: 9.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 26 GFHLVIDALKLNGIETIYNVPGIP-ITDLGRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTA 104
Cdd:PRK12474 7 GADSVVDTLLNCGVEVCFANPGTSeMHFVAALDRVPRMRPVLCLFEGVVTGAADGYGRIAGKPAVTLLHLGPGLANGLAN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 105 LANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLaiAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLPA 184
Cdd:PRK12474 87 LHNARRAASPIVNIVGDHAVEHLQYDAPLTSDIDGF--ARPVSRWVHRSASAGAVDSDVARAVQAAQSAPGGIATLIMPA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 185 KLfsqVIDADLGARSLVKVIDAAPAQLPAPAAIARALdvlkSAERPLIILGKGAAY----------AQADEAVRALVE-- 252
Cdd:PRK12474 165 DV---AWNEAAYAAQPLRGIGPAPVAAETVERIAALL----RNGKKSALLLRGSALrgapleaagrIQAKTGVRLYCDtf 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 253 ----ESGIPYVPMSMakglLPDTHPLSAGaarstALKDSDVVLLVGAR--LNWLLSHGKgKTWGEPGSKRFIQIdIEPRE 326
Cdd:PRK12474 238 apriERGAGRVPIER----IPYFHEQITA-----FLKDVEQLVLVGAKppVSFFAYPGK-PSWGAPPGCEIVYL-AQPDE 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 327 mdsnveivapvvgDIGSCVEALLDGIrkDWKGAPSnwletlrgkreANIAKMAPKLMKNSSpmcfhSALGALRTVIKERP 406
Cdd:PRK12474 307 -------------DLAQALQDLADAV--DAPAEPA-----------ARTPLALPALPKGAL-----NSLGVAQLIAHRTP 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 407 DAILVNEGANTldlARGIIDMYQPRKR----LDVgTWGVMGIGMGFAVAAAVET-GKPVLAVEGDSAFGFSGMEVETICR 481
Cdd:PRK12474 356 DQAIYADEALT---SGLFFDMSYDRARphthLPL-TGGSIGQGLPLAAGAAVAApDRKVVCPQGDGGAAYTMQALWTMAR 431
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 482 YELPVCIVIFNN------NGIYRGTDTDPTGRDPGTTVFVKNSRYD--KMMEAFGGVGVNVTTPDELKRAVDEAMNSGKP 553
Cdd:PRK12474 432 ENLDVTVVIFANrsyailNGELQRVGAQGAGRNALSMLDLHNPELNwmKIAEGLGVEASRATTAEEFSAQYAAAMAQRGP 511
|
....*..
gi 2030910552 554 TLINAEI 560
Cdd:PRK12474 512 RLIEAMI 518
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
86-560 |
7.05e-09 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 58.32 E-value: 7.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 86 KPGICLTVSAPGFLNGLTALANATTNCFPMILISG---SSEReivdlqqgDYE---EMDQLAIAKPLCKAAFRVLHAADI 159
Cdd:PRK07586 64 KPAATLLHLGPGLANGLANLHNARRARTPIVNIVGdhaTYHR--------KYDaplTSDIEALARPVSGWVRRSESAADV 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 160 GIGVARAIRAAVSGRPGGVYLDLPAklfsqviDADLG-ARSLVKVIDAAPAQLPAPAAIARALDVLKSAERPLIILGKGA 238
Cdd:PRK07586 136 AADAAAAVAAARGAPGQVATLILPA-------DVAWSeGGPPAPPPPAPAPAAVDPAAVEAAAAALRSGEPTVLLLGGRA 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 239 AYAQADEAVRALVEESGI----PYVPMSMAKG---LLPDTHPLSAGAARStALKDSDVVLLVGARlnwllshgkgktwgE 311
Cdd:PRK07586 209 LRERGLAAAARIAAATGArllaETFPARMERGagrPAVERLPYFAEQALA-QLAGVRHLVLVGAK--------------A 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 312 PGSkRFIQIDIEPR--EMDSNVEIVAPVVGDIGSCVEALLDGIrkdwkGAPSNWLETLRGKREAniakmAPKLMKNSSPM 389
Cdd:PRK07586 274 PVA-FFAYPGKPSRlvPEGCEVHTLAGPGEDAAAALEALADAL-----GAKPAAPPLAAPARPP-----LPTGALTPEAI 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 390 CfhSALGALrtvIKErpDAILVNEGANTldlARGIIDMYQPRKRLDV--GTWGVMGIGMGFAVAAAV-ETGKPVLAVEGD 466
Cdd:PRK07586 343 A--QVIAAL---LPE--NAIVVDESITS---GRGFFPATAGAAPHDWltLTGGAIGQGLPLATGAAVaCPDRKVLALQGD 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 467 SAFGFSGMEVETICRYELPVCIVIFNN------NGIYRGTDTDPTGR---------DPgTTVFVknsrydKMMEAFGGVG 531
Cdd:PRK07586 413 GSAMYTIQALWTQARENLDVTTVIFANrayailRGELARVGAGNPGPraldmldldDP-DLDWV------ALAEGMGVPA 485
|
490 500
....*....|....*....|....*....
gi 2030910552 532 VNVTTPDELKRAVDEAMNSGKPTLINAEI 560
Cdd:PRK07586 486 RRVTTAEEFADALAAALAEPGPHLIEAVV 514
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
29-556 |
3.24e-08 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 56.53 E-value: 3.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 29 LVIDALKLNGIETIYNVPGIP---ITDlgRLAQAEGLRVISFRHEQNAGNAAAIAGFLTKKPGICLTVSAPGFLNGLTAL 105
Cdd:PRK09124 8 YIAKTLEQAGVKRIWGVTGDSlngLSD--SLRRMGTIEWMHTRHEEVAAFAAGAEAQLTGELAVCAGSCGPGNLHLINGL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 106 ANATTNCFPMILISG---SSEREIVDLQQGDYEEMdqlaiakplckaaFR--------VLHAADIGIGVARAIRAAVSGR 174
Cdd:PRK09124 86 FDCHRNHVPVLAIAAhipSSEIGSGYFQETHPQEL-------------FRecshycelVSNPEQLPRVLAIAMRKAILNR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 175 pgGV-YLDLPAKLFSQVIDADLGARSLVKvidAAPAQLPAPAAIARALDVLKSAERPLIILGKGAAYAQaDEAVrALVEE 253
Cdd:PRK09124 153 --GVaVVVLPGDVALKPAPERATPHWYHA---PQPVVTPAEEELRKLAALLNGSSNITLLCGSGCAGAH-DELV-ALAET 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 254 SGIPYVPMSMAKGLLPDTHPLSAG-------AARSTALKDSDVVLLVGARLNWLLSHgkgktwgePGSKRFIQIDIEPRE 326
Cdd:PRK09124 226 LKAPIVHALRGKEHVEYDNPYDVGmtgligfSSGYHAMMNCDTLLMLGTDFPYRQFY--------PTDAKIIQIDINPGS 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 327 MDSNVEIVAPVVGDIGSCVEALLDGI-RKDWKGAPSNWLETLRGKREA--NIAKMAPklmkNSSPMcfHSALgaLRTVIK 403
Cdd:PRK09124 298 LGRRSPVDLGLVGDVKATLAALLPLLeEKTDRKFLDKALEHYRKARKGldDLAVPSD----GGKPI--HPQY--LARQIS 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 404 ER--PDAIL-VNEGANTLDLARgIIDMyQPRKRLdVGTW--GVMGIGMGFAVAA-AVETGKPVLAVEGDSAFGFSGMEVE 477
Cdd:PRK09124 370 EFaaDDAIFtCDVGTPTVWAAR-YLKM-NGKRRL-LGSFnhGSMANAMPQALGAqAAHPGRQVVALSGDGGFSMLMGDFL 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 478 TICRYELPVCIVIFNNN-----------GIYRGTDTDptgrdpgttvfVKNSRYDKMMEAFGGVGVNVTTPDELKRAVDE 546
Cdd:PRK09124 447 SLVQLKLPVKIVVFNNSvlgfvamemkaGGYLTDGTD-----------LHNPDFAAIAEACGITGIRVEKASELDGALQR 515
|
570
....*....|
gi 2030910552 547 AMNSGKPTLI 556
Cdd:PRK09124 516 AFAHDGPALV 525
|
|
| PLN02573 |
PLN02573 |
pyruvate decarboxylase |
220-555 |
9.18e-07 |
|
pyruvate decarboxylase
Pssm-ID: 215311 [Multi-domain] Cd Length: 578 Bit Score: 51.62 E-value: 9.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 220 ALDVLKSAERPLIILGKGAAYAQADEAVRALVEESGIPYVPMSMAKGLLPDTHPLSAG---AARSTA-----LKDSDVVL 291
Cdd:PLN02573 217 AAEFLNKAVKPVLVGGPKLRVAKACKAFVELADASGYPVAVMPSAKGLVPEHHPHFIGtywGAVSTPfcaeiVESADAYL 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 292 LVGARLNWLLSHG------KGKTwgepgskrfiqIDIEP-REMDSNveivAPVVGdigsCV------EALLDGIRKDwKG 358
Cdd:PLN02573 297 FAGPIFNDYSSVGyslllkKEKA-----------IIVQPdRVTIGN----GPAFG----CVlmkdflEALAKRVKKN-TT 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 359 APSNWletlrgKR----EANIAKMAPK-------LMKNSSPMcfhsaLGALRTVIKERPDAILvnegaNT--LDLARGIi 425
Cdd:PLN02573 357 AYENY------KRifvpEGEPLKSEPGeplrvnvLFKHIQKM-----LSGDTAVIAETGDSWF-----NCqkLKLPEGC- 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 426 dMYQPRKRLDVGTWGVmGIGMGFAVAAAvetGKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIFNNNGIyrgtdTDPT 505
Cdd:PLN02573 420 -GYEFQMQYGSIGWSV-GATLGYAQAAP---DKRVIACIGDGSFQVTAQDVSTMIRCGQKSIIFLINNGGY-----TIEV 489
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2030910552 506 GRDPGTTVFVKNSRYDKMMEAF-GGVG----VNVTTPDELKRAVDEAMNSGKPTL 555
Cdd:PLN02573 490 EIHDGPYNVIKNWNYTGLVDAIhNGEGkcwtAKVRTEEELIEAIATATGEKKDCL 544
|
|
| TPP_enzyme_PYR |
cd06586 |
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine ... |
29-184 |
1.77e-06 |
|
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine pyrophosphate (TPP) family, pyrimidine (PYR) binding domain; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this group. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. In the case of 2-oxoisovalerate dehydrogenase (2OXO), sulfopyruvate decarboxylase (ComDE), and the E1 component of human pyruvate dehydrogenase complex (E1- PDHc) the PYR and PP domains appear on different subunits. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. For many of these enzymes the active sites lie between PP and PYR domains on different subunits. However, for the homodimeric enzymes 1-deoxy-D-xylulose 5-phosphate synthase (DXS) and Desulfovibrio africanus pyruvate:ferredoxin oxidoreductase (PFOR), each active site lies at the interface of the PYR and PP domains from the same subunit.
Pssm-ID: 132915 [Multi-domain] Cd Length: 154 Bit Score: 48.11 E-value: 1.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 29 LVIDALKLNGIETIYNVPGIPITDLGRLAQA-EGLRVISFRHEQNAGNAAAIAGFLTKkPGICLTVSAPGFLNGLTALAN 107
Cdd:cd06586 2 AFAEVLTAWGVRHVFGYPGDEISSLLDALREgDKRIIDTVIHELGAAGAAAGYARAGG-PPVVIVTSGTGLLNAINGLAD 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2030910552 108 ATTNCFPMILISGSSEREIVDLQQGDYeeMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGrPGGVYLDLPA 184
Cdd:cd06586 81 AAAEHLPVVFLIGARGISAQAKQTFQS--MFDLGMYRSIPEANISSPSPAELPAGIDHAIRTAYAS-QGPVVVRLPR 154
|
|
| TPP_IolD |
cd02003 |
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins ... |
446-569 |
7.63e-05 |
|
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism.
Pssm-ID: 238961 [Multi-domain] Cd Length: 205 Bit Score: 44.22 E-value: 7.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 446 MGFAVAAAVET-----GKPVLAVEGDSAFGFSGMEVETICRYELPVCIVIFNNNGI------------------YRgTDT 502
Cdd:cd02003 50 MGYEIAAGLGAklakpDREVYVLVGDGSYLMLHSEIVTAVQEGLKIIIVLFDNHGFgcinnlqestgsgsfgteFR-DRD 128
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 503 DPTGRDPGTTV---FVKNSRydkmmeAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEIDPAAGSESG 569
Cdd:cd02003 129 QESGQLDGALLpvdFAANAR------SLGARVEKVKTIEELKAALAKAKASDRTTVIVIKTDPKSMTPGY 192
|
|
| TPP_SHCHC_synthase |
cd02009 |
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of ... |
440-561 |
1.68e-04 |
|
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key role in the menaquinone biosynthetic pathway, converting isochorismate and 2-oxoglutarate to SHCHC, pyruvate and carbon dioxide. The enzyme requires TPP and a divalent metal cation for activity.
Pssm-ID: 238967 [Multi-domain] Cd Length: 175 Bit Score: 42.58 E-value: 1.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 440 GVMGIGMGFAVAaaveTGKPVLAVEGDSAF-----GFSGMEVETicryeLPVCIVIFNNNG--IYR----GTDTDPTGRD 508
Cdd:cd02009 55 GTLSTALGIALA----TDKPTVLLTGDLSFlhdlnGLLLGKQEP-----LNLTIVVINNNGggIFSllpqASFEDEFERL 125
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2030910552 509 PGTTvfvKNSRYDKMMEAFGGVGVNVTTPDELKRAVDEAMNSGKPTLINAEID 561
Cdd:cd02009 126 FGTP---QGLDFEHLAKAYGLEYRRVSSLDELEQALESALAQDGPHVIEVKTD 175
|
|
| TPP_IOR_alpha |
cd02008 |
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of ... |
427-556 |
4.95e-03 |
|
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as indolepyruvate or phenylpyruvate, which are generated by the transamination of aromatic amino acids, to the corresponding aryl acetyl-CoA.
Pssm-ID: 238966 [Multi-domain] Cd Length: 178 Bit Score: 38.41 E-value: 4.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2030910552 427 MYQPRKRLDVGTwgVMGIGMGFAVAAAVET-GKPVLAVEGDSAFGFSGME--VETICRyELPVCIVIFNNNGiyrgtdTD 503
Cdd:cd02008 40 ALPPLNAIDTCT--CMGASIGVAIGMAKASeDKKVVAVIGDSTFFHSGILglINAVYN-KANITVVILDNRT------TA 110
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2030910552 504 PTGRD--PGTTVFVKNSRYDKMMEAFG-GVGVN---VTTPDELK---RAVDEAMNSGKPTLI 556
Cdd:cd02008 111 MTGGQphPGTGKTLTEPTTVIDIEALVrAIGVKrvvVVDPYDLKairEELKEALAVPGVSVI 172
|
|
| |
