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Conserved domains on  [gi|2029087645|gb|QUD20588|]
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non-structural protein 2 [Rotavirus C]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Rota_NS35 super family cl03628
Rotavirus non-structural protein 35; Rotavirus non-structural protein 35 (NS35) is a basic ...
1-311 0e+00

Rotavirus non-structural protein 35; Rotavirus non-structural protein 35 (NS35) is a basic protein which possesses RNA-binding activity and is essential for genome replication.


The actual alignment was detected with superfamily member pfam02509:

Pssm-ID: 396869  Cd Length: 317  Bit Score: 528.44  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2029087645   1 MAELACFVSFSLIEDKVKWFPINKKAVKTMLCAKVEKDQRSNYYDTILYGVAPPPEFRNRFKTTE-RNGLDYESDQYSEV 79
Cdd:pfam02509   1 MAELACFCSFHLEEDKVKFIPFNKKAIKAMLCAKVDKDDMDKFYDSIIYGIAPPPEFKKRFKTNDnRRGLDFESDMFTEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2029087645  80 ANLLADILNMVSMPTEKFQFDIVKTVVQVRHLENLLLRIKDTDDILNENVKLRVKAVMIACNLVNETETTPLTESNDIVY 159
Cdd:pfam02509  81 AMLIADALNMLKMPTEAFQFDILKRVVQIRHLENLLCRIEDPNDILFANKDLLLKATLIACGLSKEIETTILAEGGDIVF 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2029087645 160 QDQYFTITRLDYPSHKLLPLMTE---EYKITINTKTDIPERDQTAFAAYIRYNFNKFAAISHGKRHWRLIPHSQLMAHAE 236
Cdd:pfam02509 161 QDAAFTITKLDYLEHKLLPILADnfiEYKITINEDKDIPDRHQKAFAAEIRWNFNKFAAISHGKGHWRIVKHSQLANHAD 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2029087645 237 RLDRKIKSDKKHGRQFAYDDGDMAFVHPGWKACIGQLCGGTTFDVAKTSLY-SVKTSKT-VRTATNKIESDLISMVG 311
Cdd:pfam02509 241 RLDAKFKSDKKHGRNFDFDDGDMAFIHPGWKACIGQLCGGNTFDVAKRLLFqKIKPEKNpFKGASNDIEMDEIAMVG 317
 
Name Accession Description Interval E-value
Rota_NS35 pfam02509
Rotavirus non-structural protein 35; Rotavirus non-structural protein 35 (NS35) is a basic ...
1-311 0e+00

Rotavirus non-structural protein 35; Rotavirus non-structural protein 35 (NS35) is a basic protein which possesses RNA-binding activity and is essential for genome replication.


Pssm-ID: 396869  Cd Length: 317  Bit Score: 528.44  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2029087645   1 MAELACFVSFSLIEDKVKWFPINKKAVKTMLCAKVEKDQRSNYYDTILYGVAPPPEFRNRFKTTE-RNGLDYESDQYSEV 79
Cdd:pfam02509   1 MAELACFCSFHLEEDKVKFIPFNKKAIKAMLCAKVDKDDMDKFYDSIIYGIAPPPEFKKRFKTNDnRRGLDFESDMFTEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2029087645  80 ANLLADILNMVSMPTEKFQFDIVKTVVQVRHLENLLLRIKDTDDILNENVKLRVKAVMIACNLVNETETTPLTESNDIVY 159
Cdd:pfam02509  81 AMLIADALNMLKMPTEAFQFDILKRVVQIRHLENLLCRIEDPNDILFANKDLLLKATLIACGLSKEIETTILAEGGDIVF 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2029087645 160 QDQYFTITRLDYPSHKLLPLMTE---EYKITINTKTDIPERDQTAFAAYIRYNFNKFAAISHGKRHWRLIPHSQLMAHAE 236
Cdd:pfam02509 161 QDAAFTITKLDYLEHKLLPILADnfiEYKITINEDKDIPDRHQKAFAAEIRWNFNKFAAISHGKGHWRIVKHSQLANHAD 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2029087645 237 RLDRKIKSDKKHGRQFAYDDGDMAFVHPGWKACIGQLCGGTTFDVAKTSLY-SVKTSKT-VRTATNKIESDLISMVG 311
Cdd:pfam02509 241 RLDAKFKSDKKHGRNFDFDDGDMAFIHPGWKACIGQLCGGNTFDVAKRLLFqKIKPEKNpFKGASNDIEMDEIAMVG 317
 
Name Accession Description Interval E-value
Rota_NS35 pfam02509
Rotavirus non-structural protein 35; Rotavirus non-structural protein 35 (NS35) is a basic ...
1-311 0e+00

Rotavirus non-structural protein 35; Rotavirus non-structural protein 35 (NS35) is a basic protein which possesses RNA-binding activity and is essential for genome replication.


Pssm-ID: 396869  Cd Length: 317  Bit Score: 528.44  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2029087645   1 MAELACFVSFSLIEDKVKWFPINKKAVKTMLCAKVEKDQRSNYYDTILYGVAPPPEFRNRFKTTE-RNGLDYESDQYSEV 79
Cdd:pfam02509   1 MAELACFCSFHLEEDKVKFIPFNKKAIKAMLCAKVDKDDMDKFYDSIIYGIAPPPEFKKRFKTNDnRRGLDFESDMFTEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2029087645  80 ANLLADILNMVSMPTEKFQFDIVKTVVQVRHLENLLLRIKDTDDILNENVKLRVKAVMIACNLVNETETTPLTESNDIVY 159
Cdd:pfam02509  81 AMLIADALNMLKMPTEAFQFDILKRVVQIRHLENLLCRIEDPNDILFANKDLLLKATLIACGLSKEIETTILAEGGDIVF 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2029087645 160 QDQYFTITRLDYPSHKLLPLMTE---EYKITINTKTDIPERDQTAFAAYIRYNFNKFAAISHGKRHWRLIPHSQLMAHAE 236
Cdd:pfam02509 161 QDAAFTITKLDYLEHKLLPILADnfiEYKITINEDKDIPDRHQKAFAAEIRWNFNKFAAISHGKGHWRIVKHSQLANHAD 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2029087645 237 RLDRKIKSDKKHGRQFAYDDGDMAFVHPGWKACIGQLCGGTTFDVAKTSLY-SVKTSKT-VRTATNKIESDLISMVG 311
Cdd:pfam02509 241 RLDAKFKSDKKHGRNFDFDDGDMAFIHPGWKACIGQLCGGNTFDVAKRLLFqKIKPEKNpFKGASNDIEMDEIAMVG 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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