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Conserved domains on  [gi|2020981446|dbj|BCJ59598|]
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hypothetical protein Jiend_30200 [Micromonospora endophytica]

Protein Classification

(2Fe-2S)-binding protein( domain architecture ID 11449880)

(2Fe-2S)-binding protein is the small subunit of a dehydrogenase or oxidoreductase enzyme complex such as carbon monoxide dehydrogenase and isoquinoline 1-oxidoreductase; contains a a 2Fe-2S ferredoxin-type domain which binds 2Fe-2S clusters

Gene Ontology:  GO:0046872|GO:0051536|GO:0051537
PubMed:  11734195
SCOP:  3000113

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CutS COG2080
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ...
 54-206 3.27e-94

Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


:

Pssm-ID: 441683 [Multi-domain]  Cd Length: 155  Bit Score: 271.19  E-value: 3.27e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  54 VTVKVKVNGKPVTVRVDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGLARG 133
Cdd:COG2080     2 MMITLTVNGKPVEVDVDPDTPLLDVLRDDLGLTGTKFGCGHGQCGACTVLVDGKAVRSCLTLAVQADGKEITTIEGLAED 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2020981446 134 DVLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIRDAQKVMR 206
Cdd:COG2080    82 GELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYVRIVRAVKRAAAALR 154
 
Name Accession Description Interval E-value
CutS COG2080
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ...
 54-206 3.27e-94

Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441683 [Multi-domain]  Cd Length: 155  Bit Score: 271.19  E-value: 3.27e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  54 VTVKVKVNGKPVTVRVDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGLARG 133
Cdd:COG2080     2 MMITLTVNGKPVEVDVDPDTPLLDVLRDDLGLTGTKFGCGHGQCGACTVLVDGKAVRSCLTLAVQADGKEITTIEGLAED 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2020981446 134 DVLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIRDAQKVMR 206
Cdd:COG2080    82 GELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYVRIVRAVKRAAAALR 154
PRK11433 PRK11433
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
 52-201 9.82e-71

aldehyde oxidoreductase 2Fe-2S subunit; Provisional


Pssm-ID: 236910 [Multi-domain]  Cd Length: 217  Bit Score: 214.25  E-value: 9.82e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  52 ELVTVKVKVNGKPVTVRVDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGLA 131
Cdd:PRK11433   48 EISPVTLKVNGKTEQLEVDTRTTLLDALREHLHLTGTKKGCDHGQCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLG 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446 132 RGDVLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQE--------------GPAR-TDDEIRERMSGNICRCSCYPFIVD 196
Cdd:PRK11433  128 SPDNLHPMQAAFVKHDGFQCGYCTPGQICSSVAVLKEikdgipshvtvdltAAPElTADEIRERMSGNICRCGAYSNILE 207


                  ....*
gi 2020981446 197 AIRDA 201
Cdd:PRK11433  208 AIEDV 212
glyceraldDH_gamma NF041020
glyceraldehyde dehydrogenase subunit gamma;
52-206 2.90e-59

glyceraldehyde dehydrogenase subunit gamma;


Pssm-ID: 468949 [Multi-domain]  Cd Length: 162  Bit Score: 183.07  E-value: 2.90e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  52 ELVTVKVKVNGKPVTVRVDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGLA 131
Cdd:NF041020    7 EKVKIRVKVNGVWYEAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMNGKSVKSCTVLAVQADGAEITTIEGLS 86

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2020981446 132 RGDVLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIRDAQKVMR 206
Cdd:NF041020   87 KDGKLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKENPNPTEEEIRDGIHGNLCRCTGYQNIVKAVKEASQKMK 161
4hydroxCoAred TIGR03193
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts ...
 56-201 5.43e-47

4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts 4-hydroxybenzoyl-CoA to benzoyl-CoA, a common intermediate in the degradation of aromatic compounds. This protein family represents the gamma chain of this three-subunit enzyme.


Pssm-ID: 132237 [Multi-domain]  Cd Length: 148  Bit Score: 151.57  E-value: 5.43e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  56 VKVKVNGKPVTVRVDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGLARGDV 135
Cdd:TIGR03193   2 LRLTVNGRWREDAVADNMLLVDYLRDTVGLTGTKQGCDGGECGACTVLVDGRPRLACSTLAHRVAGRKVETVEGLATNGR 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2020981446 136 LHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIRDA 201
Cdd:TIGR03193  82 LSRLQQAFHERLGTQCGFCTPGMIMAAEALLRRNPSPSRDEIRAALAGNLCRCTGYVKIIESVEAA 147
Fer2_2 pfam01799
[2Fe-2S] binding domain;
126-198 3.15e-36

[2Fe-2S] binding domain;


Pssm-ID: 460336 [Multi-domain]  Cd Length: 73  Bit Score: 121.38  E-value: 3.15e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2020981446 126 TIEGLARGDvLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDD-EIRERMSGNICRCSCYPFIVDAI 198
Cdd:pfam01799   1 TIEGLAESG-GEPVQQAFAEAGAVQCGYCTPGMIMSAYALLERNPPPPTEaEIREALSGNLCRCTGYRRIVDAV 73
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 56-118 1.12e-05

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 42.38  E-value: 1.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  56 VKVKVNGKPVTVRVDPRVTLLDTLREELelTGTKKGCDRGQCGACTVHVD------------------GRRVLSCLTLVA 117
Cdd:cd00207     1 VTINVPGSGVEVEVPEGETLLDAAREAG--IDIPYSCRAGACGTCKVEVVegevdqsdpslldeeeaeGGYVLACQTRVT 78


                  .
gi 2020981446 118 T 118
Cdd:cd00207    79 D 79
 
Name Accession Description Interval E-value
CutS COG2080
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ...
 54-206 3.27e-94

Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441683 [Multi-domain]  Cd Length: 155  Bit Score: 271.19  E-value: 3.27e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  54 VTVKVKVNGKPVTVRVDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGLARG 133
Cdd:COG2080     2 MMITLTVNGKPVEVDVDPDTPLLDVLRDDLGLTGTKFGCGHGQCGACTVLVDGKAVRSCLTLAVQADGKEITTIEGLAED 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2020981446 134 DVLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIRDAQKVMR 206
Cdd:COG2080    82 GELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYVRIVRAVKRAAAALR 154
PRK11433 PRK11433
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
 52-201 9.82e-71

aldehyde oxidoreductase 2Fe-2S subunit; Provisional


Pssm-ID: 236910 [Multi-domain]  Cd Length: 217  Bit Score: 214.25  E-value: 9.82e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  52 ELVTVKVKVNGKPVTVRVDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGLA 131
Cdd:PRK11433   48 EISPVTLKVNGKTEQLEVDTRTTLLDALREHLHLTGTKKGCDHGQCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLG 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446 132 RGDVLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQE--------------GPAR-TDDEIRERMSGNICRCSCYPFIVD 196
Cdd:PRK11433  128 SPDNLHPMQAAFVKHDGFQCGYCTPGQICSSVAVLKEikdgipshvtvdltAAPElTADEIRERMSGNICRCGAYSNILE 207


                  ....*
gi 2020981446 197 AIRDA 201
Cdd:PRK11433  208 AIEDV 212
glyceraldDH_gamma NF041020
glyceraldehyde dehydrogenase subunit gamma;
52-206 2.90e-59

glyceraldehyde dehydrogenase subunit gamma;


Pssm-ID: 468949 [Multi-domain]  Cd Length: 162  Bit Score: 183.07  E-value: 2.90e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  52 ELVTVKVKVNGKPVTVRVDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGLA 131
Cdd:NF041020    7 EKVKIRVKVNGVWYEAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMNGKSVKSCTVLAVQADGAEITTIEGLS 86

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2020981446 132 RGDVLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIRDAQKVMR 206
Cdd:NF041020   87 KDGKLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKENPNPTEEEIRDGIHGNLCRCTGYQNIVKAVKEASQKMK 161
XdhA COG4630
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and ...
 60-201 9.18e-51

Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and metabolism];


Pssm-ID: 443668 [Multi-domain]  Cd Length: 476  Bit Score: 170.32  E-value: 9.18e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  60 VNGKPVTVR-VDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHV----DGRRVL----SCLTLVATVDEREVTTIEGL 130
Cdd:COG4630     5 LNGELVELSdVPPTTTLLDWLREDRGLTGTKEGCAEGDCGACTVVVgeldDGGLRYravnACILFLPQLDGKALVTVEGL 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2020981446 131 ARGDV-LHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIRDA 201
Cdd:COG4630    85 AGPDGaLHPVQQAMVDHHGSQCGFCTPGFVMSLFALYERGPAPDRADIEDALSGNLCRCTGYRPIIDAARAM 156
4hydroxCoAred TIGR03193
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts ...
 56-201 5.43e-47

4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts 4-hydroxybenzoyl-CoA to benzoyl-CoA, a common intermediate in the degradation of aromatic compounds. This protein family represents the gamma chain of this three-subunit enzyme.


Pssm-ID: 132237 [Multi-domain]  Cd Length: 148  Bit Score: 151.57  E-value: 5.43e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  56 VKVKVNGKPVTVRVDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGLARGDV 135
Cdd:TIGR03193   2 LRLTVNGRWREDAVADNMLLVDYLRDTVGLTGTKQGCDGGECGACTVLVDGRPRLACSTLAHRVAGRKVETVEGLATNGR 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2020981446 136 LHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIRDA 201
Cdd:TIGR03193  82 LSRLQQAFHERLGTQCGFCTPGMIMAAEALLRRNPSPSRDEIRAALAGNLCRCTGYVKIIESVEAA 147
xanthine_xdhA TIGR02963
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit ...
 60-197 1.19e-43

xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit (or, in eukaryotes, the N-terminal domain) of xanthine dehydrogenase, an enzyme of purine catabolism via urate. The small subunit contains both an FAD and a 2Fe-2S cofactor. Aldehyde oxidase (retinal oxidase) appears to have arisen as a neofunctionalization among xanthine dehydrogenases in eukaryotes and [Purines, pyrimidines, nucleosides, and nucleotides, Other]


Pssm-ID: 274365 [Multi-domain]  Cd Length: 467  Bit Score: 151.66  E-value: 1.19e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  60 VNGKPVTVR-VDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHV----DGRRVL-----SCLTLVATVDEREVTTIEG 129
Cdd:TIGR02963   5 LNGETVTLSdVDPTRTLLDYLREDAGLTGTKEGCAEGDCGACTVVVgelvDGGKLRyrsvnACIQFLPSLDGKAVVTVED 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2020981446 130 LARGD-VLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDA 197
Cdd:TIGR02963  85 LRQPDgRLHPVQQAMVECHGSQCGFCTPGFVMSLYALYKNSPAPSRADIEDALQGNLCRCTGYRPILDA 153
PRK09908 PRK09908
xanthine dehydrogenase iron sulfur-binding subunit XdhC;
50-203 1.40e-42

xanthine dehydrogenase iron sulfur-binding subunit XdhC;


Pssm-ID: 182139 [Multi-domain]  Cd Length: 159  Bit Score: 140.82  E-value: 1.40e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  50 SVELVTVKVKVNGKPVTVRVDPRVTLLDTLREElELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEG 129
Cdd:PRK09908    3 HSETITIECTINGMPFQLHAAPGTPLSELLREQ-GLLSVKQGCCVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEG 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2020981446 130 LARGDVLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPAR--TDDEIRERMSGNICRCSCYPFIVDAIRDAQK 203
Cdd:PRK09908   82 EAKGGKLSHVQQAYAKSGAVQCGFCTPGLIMATTAMLAKPREKplTITEIRRGLAGNLCRCTGYQMIVNTVLDCEK 157
pucE TIGR03198
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the ...
 54-203 4.78e-42

xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the Iron-sulfur cluster binding-subunit of xanthine dehydrogenase (pucE), acting in conjunction with pucC, the FAD-binding subunit and pucD, the molybdopterin binding subunit. The more common XDH complex (GenProp0640) includes the xdhA gene as the Fe-S cluster binding component.


Pssm-ID: 132242 [Multi-domain]  Cd Length: 151  Bit Score: 138.83  E-value: 4.78e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  54 VTVKVKVNGKPVTVRVDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGLARG 133
Cdd:TIGR03198   2 EQFRFTVNGQAWEVAAVPTTRLSDLLRKELQLTGTKVSCGIGRCGACSVLIDGKLANACLTMAYQADGHEITTIEGIAEN 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446 134 DvLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIRDAQK 203
Cdd:TIGR03198  82 E-LDPCQTAFLEEGGFQCGYCTPGMVVALKALFRETPQPSDEDMEEGLSGNLCRCTGYGGIIRSACRIRR 150
Se_dep_XDH TIGR03311
selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional ...
 60-206 1.28e-38

selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional xanthine dehydrogenase enzymes, which depend on molybdenum cofactor - molybdopterin bound to molybdate with two sulfur atoms as ligands. But all members of this family occur in species that contain markers for the biosynthesis of enzymes with a selenium-containing form of molybdenum cofactor. The member of this family from Enterococcus faecalis has been shown to act as a xanthine dehydrogenenase, and its activity if dependent on SelD (selenophosphate synthase), selenium, and molybdenum. [Purines, pyrimidines, nucleosides, and nucleotides, Other]


Pssm-ID: 132354 [Multi-domain]  Cd Length: 848  Bit Score: 140.75  E-value: 1.28e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  60 VNGKPVTVRVDprVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGLA--RGDVLh 137
Cdd:TIGR03311   5 VNGREVDVNEE--KKLLEFLREDLRLTGVKNGCGEGACGACTVIVNGKAVRACRFTTAKLAGKEITTVEGLTerEKDVY- 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2020981446 138 pmQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIRDAQKVMR 206
Cdd:TIGR03311  82 --AWAFAKAGAVQCGFCIPGMVISAKALLDKNPNPTEAEIKKALKGNICRCTGYVKIIKAVRLAAKAFR 148
Fer2_2 pfam01799
[2Fe-2S] binding domain;
126-198 3.15e-36

[2Fe-2S] binding domain;


Pssm-ID: 460336 [Multi-domain]  Cd Length: 73  Bit Score: 121.38  E-value: 3.15e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2020981446 126 TIEGLARGDvLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDD-EIRERMSGNICRCSCYPFIVDAI 198
Cdd:pfam01799   1 TIEGLAESG-GEPVQQAFAEAGAVQCGYCTPGMIMSAYALLERNPPPPTEaEIREALSGNLCRCTGYRRIVDAV 73
PLN02906 PLN02906
xanthine dehydrogenase
 74-199 7.27e-33

xanthine dehydrogenase


Pssm-ID: 215491 [Multi-domain]  Cd Length: 1319  Bit Score: 124.43  E-value: 7.27e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446   74 TLLDTLREeLELTGTKKGCDRGQCGACTVHVDG----------RRVLSCLTLVATVDEREVTTIEGLA-RGDVLHPMQQA 142
Cdd:PLN02906     3 TLLEYLRD-LGLTGTKLGCGEGGCGACTVMVSHydrktgkcvhYAVNACLAPLYSVEGMHVITVEGIGnRRDGLHPVQEA 81

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2020981446  143 FIERDGLQCGFCTPGQIMSAVGMVQ-EGPARTDDEIRERMSGNICRCSCYPFIVDAIR 199
Cdd:PLN02906    82 LASMHGSQCGFCTPGFIMSMYALLRsSKTPPTEEQIEECLAGNLCRCTGYRPILDAFR 139
mam_aldehyde_ox TIGR02969
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
 60-199 2.05e-32

aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.


Pssm-ID: 132014 [Multi-domain]  Cd Length: 1330  Bit Score: 123.20  E-value: 2.05e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446   60 VNGKPVTVR-VDPRVTLLDTLREELELTGTKKGCDRGQCGACTVHVDGRR----------VLSCLTLVATVDEREVTTIE 128
Cdd:TIGR02969    7 VNGRKVVEKnVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYNpstksirhhpVNACLTPICSLYGAAVTTVE 86

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2020981446  129 GLARGDV-LHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIR 199
Cdd:TIGR02969   87 GIGSTRTrLHPVQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACK 158
PLN00192 PLN00192
aldehyde oxidase
 55-197 2.23e-28

aldehyde oxidase


Pssm-ID: 215096 [Multi-domain]  Cd Length: 1344  Bit Score: 111.73  E-value: 2.23e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446   55 TVKVKVNGKPVTV-RVDPRVTLLDTLREELELTGTKKGCDRGQCGACTV----------HVDGRRVLSCLTLVATVDERE 123
Cdd:PLN00192     5 SLVFAVNGERFELsSVDPSTTLLEFLRTQTPFKSVKLGCGEGGCGACVVllskydpvldQVEDFTVSSCLTLLCSVNGCS 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  124 VTTIEGLARG-DVLHPMQQAFIERDGLQCGFCTPGQIMSAVGMV-----------QEGPAR-TDDEIRERMSGNICRCSC 190
Cdd:PLN00192    85 ITTSEGLGNSkDGFHPIHKRFAGFHASQCGFCTPGMCISLFSALvnadktdrpepPSGFSKlTVVEAEKAVSGNLCRCTG 164


                   ....*..
gi 2020981446  191 YPFIVDA 197
Cdd:PLN00192   165 YRPIVDA 171
PRK09800 PRK09800
putative hypoxanthine oxidase; Provisional
 54-206 1.04e-05

putative hypoxanthine oxidase; Provisional


Pssm-ID: 182084 [Multi-domain]  Cd Length: 956  Bit Score: 45.59  E-value: 1.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  54 VTVKVKVNGKPVTVRVDPRvtllDTLREELELTG--TKKGCDRGQ--CGACTVHVDGRRVLSCLTLVATVDEREVTTIEG 129
Cdd:PRK09800    1 MIIHFTLNGAPQELTVNPG----ENVQKLLFNMGmhSVRNSDDGFgfAGSDAIIFNGNIVNASLLIAAQLEKADIRTAES 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2020981446 130 LARGDVLHPMQQAFIERDGLQCGFCTPGQIMSAVGMVQEGPARTDDEIRERMSGNICRCSCYPFIVDAIRDAQKVMR 206
Cdd:PRK09800   77 LGKWNELSLVQQAMVDVGVVQSGYNDPAAALIITDLLDRIAAPTREEIDDALSGLFSRDAGWQQYYQVIELAVARKN 153
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 56-118 1.12e-05

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 42.38  E-value: 1.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  56 VKVKVNGKPVTVRVDPRVTLLDTLREELelTGTKKGCDRGQCGACTVHVD------------------GRRVLSCLTLVA 117
Cdd:cd00207     1 VTINVPGSGVEVEVPEGETLLDAAREAG--IDIPYSCRAGACGTCKVEVVegevdqsdpslldeeeaeGGYVLACQTRVT 78


                  .
gi 2020981446 118 T 118
Cdd:cd00207    79 D 79
Fer2_3 pfam13085
2Fe-2S iron-sulfur cluster binding domain; The 2Fe-2S ferredoxin family have a general core ...
 65-147 1.38e-05

2Fe-2S iron-sulfur cluster binding domain; The 2Fe-2S ferredoxin family have a general core structure consisting of beta(2)-alpha-beta(2) which abeta-grasp type fold. The domain is around one hundred amino acids with four conserved cysteine residues to which the 2Fe-2S cluster is ligated.


Pssm-ID: 432963 [Multi-domain]  Cd Length: 107  Bit Score: 42.61  E-value: 1.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  65 VTVRVDPRVTLLDTL---REELELTGT-KKGCDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTtieglargdvLHPMQ 140
Cdd:pfam13085  21 YEVPYEEGMTVLDALnkiKEEQDPTLAfRRSCREGICGSCAMNINGKPRLACKTLIDDLLGQDIT----------LEPLP 90


                  ....*..
gi 2020981446 141 QAFIERD 147
Cdd:pfam13085  91 GFPVIRD 97
Fer2 pfam00111
2Fe-2S iron-sulfur cluster binding domain;
58-114 2.56e-04

2Fe-2S iron-sulfur cluster binding domain;


Pssm-ID: 395061 [Multi-domain]  Cd Length: 77  Bit Score: 38.27  E-value: 2.56e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2020981446  58 VKVNGKPVTVRVDPRVTLLDTLREELeLTGTKKGCDRGQCGACTVHVDGRRVLSCLT 114
Cdd:pfam00111   1 VTINGKGVTIEVPDGETTLLDAAEEA-GIDIPYSCRGGGCGTCAVKVLEGEDQSDQS 56
PRK12386 PRK12386
fumarate reductase iron-sulfur subunit; Provisional
 92-130 4.35e-04

fumarate reductase iron-sulfur subunit; Provisional


Pssm-ID: 237086 [Multi-domain]  Cd Length: 251  Bit Score: 40.07  E-value: 4.35e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2020981446  92 CDRGQCGACTVHVDGRRVLSCLTLVATVDEREVTTIEGL 130
Cdd:PRK12386   53 CKAGKCGSCSAEINGRPRLMCMTRMSTFDEDETVTVTPM 91
PRK12576 PRK12576
succinate dehydrogenase/fumarate reductase iron-sulfur subunit;
67-130 5.40e-04

succinate dehydrogenase/fumarate reductase iron-sulfur subunit;


Pssm-ID: 237143 [Multi-domain]  Cd Length: 279  Bit Score: 39.73  E-value: 5.40e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  67 VRVDPRVTLLDTLR---EELELTGT-KKGCDRGQCGACTVHVDGRRVLSCLTLVATV--DEREVTTIEGL 130
Cdd:PRK12576   29 VKVDRFTQVTEALRrikEEQDPTLSyRASCHMAVCGSCGMKINGEPRLACKTLVLDVakKYNSVITIEPM 98
PRK06259 PRK06259
succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Provisional
 52-131 1.85e-03

succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Provisional


Pssm-ID: 235756 [Multi-domain]  Cd Length: 486  Bit Score: 38.45  E-value: 1.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2020981446  52 ELVTVKVKVNG--------KPVTVRVDPRVTLLDTLR-------EELELtgtKKGCDRGQCGACTVHVDGRRVLSCLTLV 116
Cdd:PRK06259    2 KMITITVKRFDpekdephfESYEVPVKEGMTVLDALEyinktydANIAF---RSSCRAGQCGSCAVTINGEPVLACKTEV 78

                          90
                  ....*....|....*
gi 2020981446 117 atvdeREVTTIEGLA 131
Cdd:PRK06259   79 -----EDGMIIEPLD 88
NqrF COG2871
Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF [Energy production and ...
 55-104 2.57e-03

Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF [Energy production and conversion]; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF is part of the Pathway/BioSystem: Na+-translocating NADH dehydrogenase


Pssm-ID: 442118 [Multi-domain]  Cd Length: 396  Bit Score: 37.92  E-value: 2.57e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2020981446  55 TVKVKVNGKPVTVRVDPRVTLLDTL-REELELTGtkkGCD-RGQCGACTVHV 104
Cdd:COG2871    34 EVKITINGDGKEIEVEEGQTLLDALlRQGIFLPS---ACGgGGTCGQCKVKV 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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