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Conserved domains on  [gi|2018126203|ref|YP_010030935|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Zapornia pusilla]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 3.17e-55

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 171.86  E-value: 3.17e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203   1 MTYFMFFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSLAADPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203  81 GWGDWRVMGYIVG-LVGVLVVGVFVGGFVDCWKFGVTTVDSVGVLSVRLDFSGVAMLYSWGVGVFLIAGWGLLLTLFVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 2018126203 160 ELVRGLARGTIRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 3.17e-55

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 171.86  E-value: 3.17e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203   1 MTYFMFFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSLAADPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203  81 GWGDWRVMGYIVG-LVGVLVVGVFVGGFVDCWKFGVTTVDSVGVLSVRLDFSGVAMLYSWGVGVFLIAGWGLLLTLFVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 2018126203 160 ELVRGLARGTIRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 1.86e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 55.97  E-value: 1.86e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203  17 LAVASNPSPYYGVVGLVLASVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSL-AADPYPEGWGDWRVMGYIVGLV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2018126203  96 GVLVVGVFVGGfvdcWKFGVTTVDSVGVLSVRLDFSGVAmLYSWGVGVFLIAGWGLLLTLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVLL----SASLTPAAAAAAPDVGNIEAIGEL-LFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 3.17e-55

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 171.86  E-value: 3.17e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203   1 MTYFMFFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSLAADPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203  81 GWGDWRVMGYIVG-LVGVLVVGVFVGGFVDCWKFGVTTVDSVGVLSVRLDFSGVAMLYSWGVGVFLIAGWGLLLTLFVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 2018126203 160 ELVRGLARGTIRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 7.08e-54

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 168.40  E-value: 7.08e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203   1 MTYFMFFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSLAADPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203  81 GWGDWRVMGYIVGLVGVLVVGVFVGGFVDCWKFGVTTVDSVGVLSVRLDFSGVAMLYSWGVGVFLIAGWGLLLTLFVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 2018126203 161 LVRGLARGTIRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 2.28e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 159.63  E-value: 2.28e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203   1 MTYFMFFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSLAADPYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203  81 GWGDWRVMGYIVGLVGVLVVGVFVGGFVDCWKFgVTTVDSVGVLSVRLDFSGVAMLYSWGVGVFLIAGWGLLLTLFVVLE 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEF-LFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                         170
                  ....*....|...
gi 2018126203 161 LVRGLARGTIRAV 173
Cdd:MTH00065  160 VTRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-164 3.15e-27

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 100.65  E-value: 3.15e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203   1 MTYFMFFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSLAADPYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203  81 GWGD-WRVMGYIVGLVGVLVVGVFVGGFVDCWKFGVTTV--------DSVGVLSVRLDFSGVAMLYSWGVGVFLIAGWGL 151
Cdd:MTH00109   82 TWVSnKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNglgdwviyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 2018126203 152 LLTLFVVLELVRG 164
Cdd:MTH00109  162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 2.70e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 92.74  E-value: 2.70e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203   1 MTYFMFFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSLAADPYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203  81 GWGDWRVMGYIVGLVGVLVVGVFVGgfvdCWKFGVTTVDSVGVLSvRLDFSGVAMLYSWGVGVFLIAGWGLLLTLFVVLE 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYF----YGGWEMLSWMGVDEAN-NLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                         170
                  ....*....|...
gi 2018126203 161 LVRGLARGTIRAV 173
Cdd:MTH00214  156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 10-172 8.02e-14

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 65.31  E-value: 8.02e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203  10 VCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSLAADPYPEgwgdwrVMG 89
Cdd:MTH00045    8 ILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS------VSN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203  90 YIVGLVGVLVVGVFVGGFVDCWkfgVTTVDSVGVLSVRLDFSGVAMLYSWGVGVFLIAGWGLLLTLFVVLELVRGLARGT 169
Cdd:MTH00045   82 LGEVLVLSLLLSLWVFISFDNF---LELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSS 158


                  ...
gi 2018126203 170 IRA 172
Cdd:MTH00045  159 LRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 1.86e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 55.97  E-value: 1.86e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203  17 LAVASNPSPYYGVVGLVLASVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSL-AADPYPEGWGDWRVMGYIVGLV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2018126203  96 GVLVVGVFVGGfvdcWKFGVTTVDSVGVLSVRLDFSGVAmLYSWGVGVFLIAGWGLLLTLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVLL----SASLTPAAAAAAPDVGNIEAIGEL-LFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 5-73 1.05e-04

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 40.87  E-value: 1.05e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2018126203   5 MFFLGVcfVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSL 73
Cdd:MTH00021    1 FFSLGI--IGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 44-74 4.51e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 35.94  E-value: 4.51e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2018126203  44 LSLGLSFVSLVLFMVYLGGMLVVFLYSVSLA 74
Cdd:MTH00166   41 LMMKSFWFSYILFLIFLGGMLVLFIYITSLA 71
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 5-74 4.86e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 36.02  E-value: 4.86e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018126203   5 MFFLGVCFVLGGLAVASNPSPYYGVVGLVLaSVVGCGWLLSLGLSFVSLVLFMVYLGGMLVVFLYSVSLA 74
Cdd:MTH00152    4 MILLSVCFSLFLLLPLSKQPLSLGLVLLLL-SLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLS 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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