|
Name |
Accession |
Description |
Interval |
E-value |
| VirB10 |
cd16429 |
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains ... |
1692-1888 |
2.01e-53 |
|
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains VirB10, a component of the type IV secretion system (T4SS), including homologs TrbI, TraF, TrwE and TraL. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10, interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both, the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. TrwE in R33 plasmid has been shown to be anchored to the inner membrane and its C-terminal is necessary for conjugation; the transmembrane domains of TrwB and TrwE are involved in TrwB-TrwE interactions. TraF protein of the RP4 plasmid is involved in circularization of pilin subunits of P-type pili. In gonococcal genetic island (GGI) of Neisseria gonorrhoeae, T4SS encodes TrbI and circularization occurs via a covalent intermediate between the C terminus of putative pilin protein TraA and TrbI. :
Pssm-ID: 319755 Cd Length: 180 Bit Score: 185.40 E-value: 2.01e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1692 LAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGVII 1770
Cdd:cd16429 1 LPAGTVIPAVLETAINSDLPGQVRAQVTRDVYDSTGRVLLIPKGSRLIGEYNSgVAQG---QSRVFVVWTRLITPDGVSI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1771 PLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdkliglgkgrSERTPEFNYALGQAINGSMQS 1850
Cdd:cd16429 78 DLDSMPGADALGRAGLKGDVDNHFWERFGGALLLSLISDGAQAA---------------SSSASNSNSAGQAAGSNTGQS 142
|
170 180 190
....*....|....*....|....*....|....*...
gi 2004286192 1851 SAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFS 1888
Cdd:cd16429 143 LGQVASQILERNLNIPPTITIRQGTRINIFVARDLDFS 180
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
9-73 |
7.78e-28 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. :
Pssm-ID: 405299 Cd Length: 65 Bit Score: 107.80 E-value: 7.78e-28
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2004286192 9 ETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSE 73
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEEITDDSNDQ 65
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
139-203 |
7.10e-26 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. :
Pssm-ID: 405299 Cd Length: 65 Bit Score: 102.41 E-value: 7.10e-26
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2004286192 139 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEETQTQMDSE 203
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEEITDDSNDQ 65
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
269-325 |
1.65e-21 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. :
Pssm-ID: 405299 Cd Length: 65 Bit Score: 89.70 E-value: 1.65e-21
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2004286192 269 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 325
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 57
|
|
| PTZ00121 super family |
cl31754 |
MAEBL; Provisional |
846-1348 |
5.07e-14 |
|
MAEBL; Provisional The actual alignment was detected with superfamily member PTZ00121:
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 78.26 E-value: 5.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 846 KTEAEKKECEKLLTPEARKLLEEAKKSVKAYLDCVSQAKteaEKKECEKLLTPEARKLLEE*AKESVKAYLDcvsqaknE 925
Cdd:PTZ00121 1237 KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAE---EARKADELKKAEEKKKADEAKKAEEKKKAD-------E 1306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 926 AEKKECEKLLTLESKKKLEEAKKSVKayldcvsqaktEAEKKECEKLLTPEAKKLLEQQALDCLKNA--KTEADKKRCVK 1003
Cdd:PTZ00121 1307 AKKKAEEAKKADEAKKKAEEAKKKAD-----------AAKKKAEEAKKAAEAAKAEAEAAADEAEAAeeKAEAAEKKKEE 1375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1004 DLPKDLQKKVLAKESLKAykDCVSKARNEKEKKECEKLLTPEAKKLLEEAKKSVKAyldcvSQAKTEAEKKECEKLLTPE 1083
Cdd:PTZ00121 1376 AKKKADAAKKKAEEKKKA--DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEE-----KKKADEAKKKAEEAKKADE 1448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1084 ARKLLEEAKESVKAYKDCVSKAR-NEKEKKECEKLLTPEAKKLLEQqvldclknAKTEADKKRCVKDLPKDLQKKVLAKE 1162
Cdd:PTZ00121 1449 AKKKAEEAKKAEEAKKKAEEAKKaDEAKKKAEEAKKADEAKKKAEE--------AKKKADEAKKAAEAKKKADEAKKAEE 1520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1163 SVKAyldcvSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYK----DCLSQARNEEERRACEKLLTPEARKLLEQEVK 1238
Cdd:PTZ00121 1521 AKKA-----DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeekKKAEEAKKAEEDKNMALRKAEEAKKAEEARIE 1595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1239 KSIKAYLDCVSRARNEKEKKECEKLLTPEARKFL-AKQVLNCLEKAGNEEERKAclKNLPKDLQENILAKESLKAY---- 1313
Cdd:PTZ00121 1596 EVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEeEKKKVEQLKKKEAEEKKKA--EELKKAEEENKIKAAEEAKKaeed 1673
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 2004286192 1314 KDCLSQARNEEE----------RRACEKLLTPEARKLLEQEVKKS 1348
Cdd:PTZ00121 1674 KKKAEEAKKAEEdekkaaealkKEAEEAKKAEELKKKEAEEKKKA 1718
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
622-653 |
4.51e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment. :
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 39.45 E-value: 4.51e-04
10 20 30
....*....|....*....|....*....|..
gi 2004286192 622 AYKDCVSKARNEKEKQECEKLLTPEARKKLEQ 653
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
553-584 |
6.62e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment. :
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 38.68 E-value: 6.62e-04
10 20 30
....*....|....*....|....*....|..
gi 2004286192 553 EYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQ 584
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| SMC_N super family |
cl47134 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
109-942 |
7.90e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination. The actual alignment was detected with superfamily member pfam02463:
Pssm-ID: 481474 [Multi-domain] Cd Length: 1161 Bit Score: 44.58 E-value: 7.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 109 LDEETQELNEEDDQENNEYQEETQTDLIDDETSKKTQQHSpQDLSNEEATEANHFENLLKESKESSDhhldnpTETQTNF 188
Cdd:pfam02463 200 LKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERI-DLLQELLRDEQEEIESSKQEIEKEEE------KLAQVLK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 189 DGDKSEETQTQMDSEGNETSessngSLADKLFKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDD 268
Cdd:pfam02463 273 ENKEEEKEKKLQEEELKLLA-----KEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKEL 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 269 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDH-----HLDNPTETQTNFDGDKSEEITDDSNDQEIIKGSKKKY 343
Cdd:pfam02463 348 EIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERlssaaKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKE 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 344 IIGGIVVAVLIVIILFSRsifhyfmpLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTL 423
Cdd:pfam02463 428 ELEILEEEEESIELKQGK--------LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERS 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 424 YNYLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSL 503
Cdd:pfam02463 500 QKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARK 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 504 LNQQKVQVALDCLKNAKtdEERNECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEaEKNKCLKGLSKEAIERLK 583
Cdd:pfam02463 580 LRLLIPKLKLPLKSIAV--LEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK-ESAKAKESGLRKGVSLEE 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 584 QQALDCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKDCVSKARNEKEKQECEKLLTPEARKKLEQQVLDCLKNAK 663
Cdd:pfam02463 657 GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINE 736
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 664 TDEERKKCLKDLPKDLQSDILAKESLKAYKDCVSQAKTEAEKKEcekllTPEAKKLLEEEAKESVKAYLDCVSQAKTEAE 743
Cdd:pfam02463 737 ELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEER-----EKTEKLKVEEEKEEKLKAQEEELRALEEELK 811
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 744 KKECEKLLTPEAKKKLEEAKKSVKAYLdcvsrARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTDKERKKCLKDLPK 823
Cdd:pfam02463 812 EEAELLEEEQLLIEQEEKIKEEELEEL-----ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 824 DLQKKVLAKESVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKL 903
Cdd:pfam02463 887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966
|
810 820 830
....*....|....*....|....*....|....*....
gi 2004286192 904 LEE*AKESVKAYLDCVSQAKNEAEKKECEKLLTLESKKK 942
Cdd:pfam02463 967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKK 1005
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| VirB10 |
cd16429 |
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains ... |
1692-1888 |
2.01e-53 |
|
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains VirB10, a component of the type IV secretion system (T4SS), including homologs TrbI, TraF, TrwE and TraL. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10, interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both, the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. TrwE in R33 plasmid has been shown to be anchored to the inner membrane and its C-terminal is necessary for conjugation; the transmembrane domains of TrwB and TrwE are involved in TrwB-TrwE interactions. TraF protein of the RP4 plasmid is involved in circularization of pilin subunits of P-type pili. In gonococcal genetic island (GGI) of Neisseria gonorrhoeae, T4SS encodes TrbI and circularization occurs via a covalent intermediate between the C terminus of putative pilin protein TraA and TrbI.
Pssm-ID: 319755 Cd Length: 180 Bit Score: 185.40 E-value: 2.01e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1692 LAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGVII 1770
Cdd:cd16429 1 LPAGTVIPAVLETAINSDLPGQVRAQVTRDVYDSTGRVLLIPKGSRLIGEYNSgVAQG---QSRVFVVWTRLITPDGVSI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1771 PLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdkliglgkgrSERTPEFNYALGQAINGSMQS 1850
Cdd:cd16429 78 DLDSMPGADALGRAGLKGDVDNHFWERFGGALLLSLISDGAQAA---------------SSSASNSNSAGQAAGSNTGQS 142
|
170 180 190
....*....|....*....|....*....|....*...
gi 2004286192 1851 SAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFS 1888
Cdd:cd16429 143 LGQVASQILERNLNIPPTITIRQGTRINIFVARDLDFS 180
|
|
| T4SS_VirB10 |
NF038091 |
type IV secretion system protein VirB10; Members of this family are VirB10, an outer ... |
1686-1893 |
1.49e-49 |
|
type IV secretion system protein VirB10; Members of this family are VirB10, an outer membrane-associated protein from the apparatus of protein type IV secretion systems (T4SS). The model attempts to exclude related TraI proteins of conjugal transfer systems as well as the ComB10 protein of a DNA-translocating competence protein of Helicobacter pylori. Because the N-terminal regions of VirB10 proteins are highly variable, the model
Pssm-ID: 468345 Cd Length: 197 Bit Score: 175.06 E-value: 1.49e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1686 SDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAIT 1764
Cdd:NF038091 5 GDRDLLLTQGTMIPCVLETAIDSDLPGMVRCVVTRDVYSANGRVVLIERGSRVIGEYQSgLSQG---QARVFVLWTRIET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1765 PDGVIIPLANAqAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdkligLGKGRSERTPEFNYalGQAI 1844
Cdd:NF038091 82 PDGVIVNLDSP-GTDELGRSGLPGYVDNHFWERFGGAILLSLIGDAGQYA----------ANKGQNGNGSGNGN--SVNF 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2004286192 1845 NGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDV 1893
Cdd:NF038091 149 ENTSQAASDMASEALENTINIPPTLYKNQGDRINIFVARDLDFSGVYEL 197
|
|
| VirB10 |
COG2948 |
Type IV secretory pathway, VirB10 component [Intracellular trafficking, secretion, and ... |
1687-1891 |
1.55e-43 |
|
Type IV secretory pathway, VirB10 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442191 [Multi-domain] Cd Length: 309 Bit Score: 161.66 E-value: 1.55e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1687 DPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITP 1765
Cdd:COG2948 123 DSPYLLPAGTVIPAVLETGINSDLPGQITAQVTEDVYSATGRVLLIPQGSRLIGEYDSgVSFG---QSRVLVVWTRLITP 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1766 DGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQtapiialdkligLGKGRSERTpefnyaLGQAI- 1844
Cdd:COG2948 200 DGVSIDLDSMPGTDALGRAGLEGQVDNHWWERFGAALLLSLLGDGAE------------LAASSDEGD------LSTAIr 261
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2004286192 1845 NGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVY 1891
Cdd:COG2948 262 ENTAQSLSQAAQQILERNLNIPPTLTIRQGTRVRVIVARDLDFSSPY 308
|
|
| TrbI |
pfam03743 |
Bacterial conjugation TrbI-like protein; Although not essential for conjugation, the TrbI ... |
1691-1886 |
5.68e-42 |
|
Bacterial conjugation TrbI-like protein; Although not essential for conjugation, the TrbI protein greatly increase the conjugational efficiency.
Pssm-ID: 427480 Cd Length: 187 Bit Score: 152.81 E-value: 5.68e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1691 VLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWN-MNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGV 1768
Cdd:pfam03743 1 YLPAGTVIPAVLITGINSDLPGQVTAQVTEPVYDsATGRALLIPKGSRLIGEYGSgVAYG---QERVLVVWTRLICPDGV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1769 IIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdklIGLGKGRSERTPEFNYALGQAINGSM 1848
Cdd:pfam03743 78 SIDLDSPGGVDALGRAGLRGRVDNHFGQRFGAALLLSLLGGGGELA--------NAASSNSTSTSTGNDNLLGAVGSGAG 149
|
170 180 190
....*....|....*....|....*....|....*...
gi 2004286192 1849 QSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDID 1886
Cdd:pfam03743 150 QALSQLAQQILERALNIPPTITVRQGTRVRIIVNRDLD 187
|
|
| VirB10_subf |
NF041422 |
VirB10/TraB/TrbI family type IV secretion system protein; |
1687-1895 |
4.23e-30 |
|
VirB10/TraB/TrbI family type IV secretion system protein;
Pssm-ID: 469313 Cd Length: 404 Bit Score: 125.13 E-value: 4.23e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1687 DPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS--VKGGtpiMTRLMIVFTKAIT 1764
Cdd:NF041422 210 DPDLYIPENTYIPCSLDRRFVSDVAGKISCTISEDVYSASGHVKLIPKGTTARGVYKTgtLKHG---QGRMFIIWTELRT 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1765 PD--GVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPiialdkliGLGKGRSERTpefNYAlgq 1842
Cdd:NF041422 287 PEppYLDIPLVDTQAAGQLGEAGIDGWIDTHFWERFGNALMLSTVQDVAAAAS--------GSAPGKDRNT---DYT--- 352
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2004286192 1843 aiNGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKI 1895
Cdd:NF041422 353 --ENSRQATAEMAKTALENSINIPPTLYKNQGDIIGLITGQDIDFSSIYQLRM 403
|
|
| PRK13855 |
PRK13855 |
type IV secretion system protein VirB10; Provisional |
1688-1900 |
3.05e-29 |
|
type IV secretion system protein VirB10; Provisional
Pssm-ID: 172376 Cd Length: 376 Bit Score: 121.93 E-value: 3.05e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1688 PTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQsvKGGTPIMTRLMIVFTKAITPDG 1767
Cdd:PRK13855 178 PDFMVTQGTIIPCILQTAIDTNLAGYVKCVLPQDIRGTTNNVVLLDRGTTVVGEIQ--RGLQQGDARVFVLWDRAETPDH 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1768 VIIPLAnAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPIIAldkliglgkGRSERTPEFNyalgqaingS 1847
Cdd:PRK13855 256 AMISLS-SPGADELGRSGLPGTVDNHFWQRFSGAMLLSVVQGAFQAASTYA---------GSSGGGTSFN---------S 316
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2004286192 1848 MQSS-AQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSV 1900
Cdd:PRK13855 317 FQNNgEQTADTALKATINIPPTLKKNQGDTVSIFVARDLDFSGIYQLRMTGGAT 370
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
9-73 |
7.78e-28 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
Pssm-ID: 405299 Cd Length: 65 Bit Score: 107.80 E-value: 7.78e-28
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2004286192 9 ETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSE 73
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEEITDDSNDQ 65
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
139-203 |
7.10e-26 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
Pssm-ID: 405299 Cd Length: 65 Bit Score: 102.41 E-value: 7.10e-26
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2004286192 139 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEETQTQMDSE 203
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEEITDDSNDQ 65
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
269-325 |
1.65e-21 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
Pssm-ID: 405299 Cd Length: 65 Bit Score: 89.70 E-value: 1.65e-21
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2004286192 269 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 325
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 57
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
846-1348 |
5.07e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 78.26 E-value: 5.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 846 KTEAEKKECEKLLTPEARKLLEEAKKSVKAYLDCVSQAKteaEKKECEKLLTPEARKLLEE*AKESVKAYLDcvsqaknE 925
Cdd:PTZ00121 1237 KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAE---EARKADELKKAEEKKKADEAKKAEEKKKAD-------E 1306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 926 AEKKECEKLLTLESKKKLEEAKKSVKayldcvsqaktEAEKKECEKLLTPEAKKLLEQQALDCLKNA--KTEADKKRCVK 1003
Cdd:PTZ00121 1307 AKKKAEEAKKADEAKKKAEEAKKKAD-----------AAKKKAEEAKKAAEAAKAEAEAAADEAEAAeeKAEAAEKKKEE 1375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1004 DLPKDLQKKVLAKESLKAykDCVSKARNEKEKKECEKLLTPEAKKLLEEAKKSVKAyldcvSQAKTEAEKKECEKLLTPE 1083
Cdd:PTZ00121 1376 AKKKADAAKKKAEEKKKA--DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEE-----KKKADEAKKKAEEAKKADE 1448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1084 ARKLLEEAKESVKAYKDCVSKAR-NEKEKKECEKLLTPEAKKLLEQqvldclknAKTEADKKRCVKDLPKDLQKKVLAKE 1162
Cdd:PTZ00121 1449 AKKKAEEAKKAEEAKKKAEEAKKaDEAKKKAEEAKKADEAKKKAEE--------AKKKADEAKKAAEAKKKADEAKKAEE 1520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1163 SVKAyldcvSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYK----DCLSQARNEEERRACEKLLTPEARKLLEQEVK 1238
Cdd:PTZ00121 1521 AKKA-----DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeekKKAEEAKKAEEDKNMALRKAEEAKKAEEARIE 1595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1239 KSIKAYLDCVSRARNEKEKKECEKLLTPEARKFL-AKQVLNCLEKAGNEEERKAclKNLPKDLQENILAKESLKAY---- 1313
Cdd:PTZ00121 1596 EVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEeEKKKVEQLKKKEAEEKKKA--EELKKAEEENKIKAAEEAKKaeed 1673
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 2004286192 1314 KDCLSQARNEEE----------RRACEKLLTPEARKLLEQEVKKS 1348
Cdd:PTZ00121 1674 KKKAEEAKKAEEdekkaaealkKEAEEAKKAEELKKKEAEEKKKA 1718
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
17-331 |
4.13e-07 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 55.30 E-value: 4.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 17 DSPQDLSNEEATEANhfenllkESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSEGNETSESSNGSLADklfkkarkl 96
Cdd:NF033609 568 DSGSDSSNSDSGSDS-------GSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSA--------- 631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 97 vdnkkpftQQKNLDEETQELNEEDDQENNEYQEETQTDlIDDETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDH 176
Cdd:NF033609 632 --------SDSDSASDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 702
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 177 HLDNPTETQTNFDGDKSEETQTQMDSEGNETSESSNGSLADklfKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNE 256
Cdd:NF033609 703 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD---SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 779
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2004286192 257 YQEETQTDlIDDETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEEITDDSN 331
Cdd:NF033609 780 SDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 853
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
9-214 |
2.59e-06 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 52.60 E-value: 2.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 9 ETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSEGNETSESSNGSLADK 88
Cdd:NF033609 665 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 89 LfKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDDETSkKTQQHSPQDLSNEEATEANHFENLLK 168
Cdd:NF033609 745 D-SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDSDSDSDSDSDSDS 822
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2004286192 169 ESKESSDHHLDNPTETQTNFDGDKSEETQTQMDSEGNETSESSNGS 214
Cdd:NF033609 823 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGS 868
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
9-266 |
3.12e-06 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 52.60 E-value: 3.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 9 ETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSEGNETSESSNGSLADk 88
Cdd:NF033609 659 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD- 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 89 lfkkarKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDlIDDETSKKTQQHSPQDLSNEEATEANHFENLLK 168
Cdd:NF033609 738 ------SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 810
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 169 ESKESSDHHLDNPTETQTNFDGDKSEETQTQMDSEGNETSESSNGSLADKLFKKARKLVDNKKPFTQQKNLDEETQELNE 248
Cdd:NF033609 811 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPPNSPKNGTNASNKNEA 890
|
250 260
....*....|....*....|.
gi 2004286192 249 EDDQE---NNEYQEETQTDLI 266
Cdd:NF033609 891 KDSKEplpDTGSEDEANTSLI 911
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
1204-1235 |
2.04e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 40.22 E-value: 2.04e-04
10 20 30
....*....|....*....|....*....|..
gi 2004286192 1204 AYKDCLSQARNEEERRACEKLLTPEARKLLEQ 1235
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
790-970 |
2.64e-04 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 45.22 E-value: 2.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 790 TPEAKKLLEQQALDCLKNAKTDKERKKCLKDLPKDLQKKVLAKESVKAYLDCVSQAKTEAEKKECEKLLTPEA---RKLL 866
Cdd:TIGR02794 66 EQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAeaeRKAK 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 867 EEAKKsvKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEE*AKESVKAYldcVSQAKNEAEKKECEKlltlESKKKLEEA 946
Cdd:TIGR02794 146 EEAAK--QAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAE---EAKAKAEAAKAKAAA----EAAAKAEAE 216
|
170 180
....*....|....*....|....
gi 2004286192 947 KKsvkayldcvSQAKTEAEKKECE 970
Cdd:TIGR02794 217 AA---------AAAAAEAERKADE 231
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
622-653 |
4.51e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 39.45 E-value: 4.51e-04
10 20 30
....*....|....*....|....*....|..
gi 2004286192 622 AYKDCVSKARNEKEKQECEKLLTPEARKKLEQ 653
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
553-584 |
6.62e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 38.68 E-value: 6.62e-04
10 20 30
....*....|....*....|....*....|..
gi 2004286192 553 EYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQ 584
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
109-942 |
7.90e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 44.58 E-value: 7.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 109 LDEETQELNEEDDQENNEYQEETQTDLIDDETSKKTQQHSpQDLSNEEATEANHFENLLKESKESSDhhldnpTETQTNF 188
Cdd:pfam02463 200 LKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERI-DLLQELLRDEQEEIESSKQEIEKEEE------KLAQVLK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 189 DGDKSEETQTQMDSEGNETSessngSLADKLFKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDD 268
Cdd:pfam02463 273 ENKEEEKEKKLQEEELKLLA-----KEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKEL 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 269 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDH-----HLDNPTETQTNFDGDKSEEITDDSNDQEIIKGSKKKY 343
Cdd:pfam02463 348 EIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERlssaaKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKE 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 344 IIGGIVVAVLIVIILFSRsifhyfmpLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTL 423
Cdd:pfam02463 428 ELEILEEEEESIELKQGK--------LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERS 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 424 YNYLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSL 503
Cdd:pfam02463 500 QKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARK 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 504 LNQQKVQVALDCLKNAKtdEERNECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEaEKNKCLKGLSKEAIERLK 583
Cdd:pfam02463 580 LRLLIPKLKLPLKSIAV--LEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK-ESAKAKESGLRKGVSLEE 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 584 QQALDCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKDCVSKARNEKEKQECEKLLTPEARKKLEQQVLDCLKNAK 663
Cdd:pfam02463 657 GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINE 736
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 664 TDEERKKCLKDLPKDLQSDILAKESLKAYKDCVSQAKTEAEKKEcekllTPEAKKLLEEEAKESVKAYLDCVSQAKTEAE 743
Cdd:pfam02463 737 ELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEER-----EKTEKLKVEEEKEEKLKAQEEELRALEEELK 811
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 744 KKECEKLLTPEAKKKLEEAKKSVKAYLdcvsrARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTDKERKKCLKDLPK 823
Cdd:pfam02463 812 EEAELLEEEQLLIEQEEKIKEEELEEL-----ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 824 DLQKKVLAKESVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKL 903
Cdd:pfam02463 887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966
|
810 820 830
....*....|....*....|....*....|....*....
gi 2004286192 904 LEE*AKESVKAYLDCVSQAKNEAEKKECEKLLTLESKKK 942
Cdd:pfam02463 967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKK 1005
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| VirB10 |
cd16429 |
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains ... |
1692-1888 |
2.01e-53 |
|
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains VirB10, a component of the type IV secretion system (T4SS), including homologs TrbI, TraF, TrwE and TraL. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10, interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both, the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. TrwE in R33 plasmid has been shown to be anchored to the inner membrane and its C-terminal is necessary for conjugation; the transmembrane domains of TrwB and TrwE are involved in TrwB-TrwE interactions. TraF protein of the RP4 plasmid is involved in circularization of pilin subunits of P-type pili. In gonococcal genetic island (GGI) of Neisseria gonorrhoeae, T4SS encodes TrbI and circularization occurs via a covalent intermediate between the C terminus of putative pilin protein TraA and TrbI.
Pssm-ID: 319755 Cd Length: 180 Bit Score: 185.40 E-value: 2.01e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1692 LAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGVII 1770
Cdd:cd16429 1 LPAGTVIPAVLETAINSDLPGQVRAQVTRDVYDSTGRVLLIPKGSRLIGEYNSgVAQG---QSRVFVVWTRLITPDGVSI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1771 PLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdkliglgkgrSERTPEFNYALGQAINGSMQS 1850
Cdd:cd16429 78 DLDSMPGADALGRAGLKGDVDNHFWERFGGALLLSLISDGAQAA---------------SSSASNSNSAGQAAGSNTGQS 142
|
170 180 190
....*....|....*....|....*....|....*...
gi 2004286192 1851 SAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFS 1888
Cdd:cd16429 143 LGQVASQILERNLNIPPTITIRQGTRINIFVARDLDFS 180
|
|
| T4SS_VirB10 |
NF038091 |
type IV secretion system protein VirB10; Members of this family are VirB10, an outer ... |
1686-1893 |
1.49e-49 |
|
type IV secretion system protein VirB10; Members of this family are VirB10, an outer membrane-associated protein from the apparatus of protein type IV secretion systems (T4SS). The model attempts to exclude related TraI proteins of conjugal transfer systems as well as the ComB10 protein of a DNA-translocating competence protein of Helicobacter pylori. Because the N-terminal regions of VirB10 proteins are highly variable, the model
Pssm-ID: 468345 Cd Length: 197 Bit Score: 175.06 E-value: 1.49e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1686 SDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAIT 1764
Cdd:NF038091 5 GDRDLLLTQGTMIPCVLETAIDSDLPGMVRCVVTRDVYSANGRVVLIERGSRVIGEYQSgLSQG---QARVFVLWTRIET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1765 PDGVIIPLANAqAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdkligLGKGRSERTPEFNYalGQAI 1844
Cdd:NF038091 82 PDGVIVNLDSP-GTDELGRSGLPGYVDNHFWERFGGAILLSLIGDAGQYA----------ANKGQNGNGSGNGN--SVNF 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2004286192 1845 NGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDV 1893
Cdd:NF038091 149 ENTSQAASDMASEALENTINIPPTLYKNQGDRINIFVARDLDFSGVYEL 197
|
|
| VirB10 |
COG2948 |
Type IV secretory pathway, VirB10 component [Intracellular trafficking, secretion, and ... |
1687-1891 |
1.55e-43 |
|
Type IV secretory pathway, VirB10 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442191 [Multi-domain] Cd Length: 309 Bit Score: 161.66 E-value: 1.55e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1687 DPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITP 1765
Cdd:COG2948 123 DSPYLLPAGTVIPAVLETGINSDLPGQITAQVTEDVYSATGRVLLIPQGSRLIGEYDSgVSFG---QSRVLVVWTRLITP 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1766 DGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQtapiialdkligLGKGRSERTpefnyaLGQAI- 1844
Cdd:COG2948 200 DGVSIDLDSMPGTDALGRAGLEGQVDNHWWERFGAALLLSLLGDGAE------------LAASSDEGD------LSTAIr 261
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2004286192 1845 NGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVY 1891
Cdd:COG2948 262 ENTAQSLSQAAQQILERNLNIPPTLTIRQGTRVRVIVARDLDFSSPY 308
|
|
| TrbI |
pfam03743 |
Bacterial conjugation TrbI-like protein; Although not essential for conjugation, the TrbI ... |
1691-1886 |
5.68e-42 |
|
Bacterial conjugation TrbI-like protein; Although not essential for conjugation, the TrbI protein greatly increase the conjugational efficiency.
Pssm-ID: 427480 Cd Length: 187 Bit Score: 152.81 E-value: 5.68e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1691 VLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWN-MNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGV 1768
Cdd:pfam03743 1 YLPAGTVIPAVLITGINSDLPGQVTAQVTEPVYDsATGRALLIPKGSRLIGEYGSgVAYG---QERVLVVWTRLICPDGV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1769 IIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdklIGLGKGRSERTPEFNYALGQAINGSM 1848
Cdd:pfam03743 78 SIDLDSPGGVDALGRAGLRGRVDNHFGQRFGAALLLSLLGGGGELA--------NAASSNSTSTSTGNDNLLGAVGSGAG 149
|
170 180 190
....*....|....*....|....*....|....*...
gi 2004286192 1849 QSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDID 1886
Cdd:pfam03743 150 QALSQLAQQILERALNIPPTITVRQGTRVRIIVNRDLD 187
|
|
| VirB10_like |
cd16426 |
VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS); This ... |
1692-1888 |
1.28e-35 |
|
VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS); This family contains VirB10, a component of the type IV secretion system (T4SS) and its homologs, including TraB, TraF, IcmE, and similar proteins. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10 interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. In Gram-negative bacterial pathogen Helicobacter pylori, an important aetiological agent of gastroduodenal disease in humans, the comB3 gene encodes protein with best homologies to TraS/TraB from the Pseudomonas aeruginosa conjugative plasmid RP1 and TrbI of plasmid RP4 and VirB10 from the Ti plasmid of Agrobacterium tumefaciens, as well as DotG/IcmE of Legionella pneumophila.
Pssm-ID: 319754 [Multi-domain] Cd Length: 151 Bit Score: 133.05 E-value: 1.28e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1692 LAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQsvkGGTPIMTRLMIVFTKAITPDGVIIP 1771
Cdd:cd16426 1 LLPGTIIPAVLLTGIDSDLPGPVLARVTRDVYDPNGGRLLIPKGSRLIGEYY---GDLSSQERVLVRWTRLICPDGVSID 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1772 LANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVnsflqtapiialdkliglgkgrsertpefnyalgqaingsmqsS 1851
Cdd:cd16426 78 LDSVAGADALGRAGLRGDVDNHFGERFGGALLASLL-------------------------------------------S 114
|
170 180 190
....*....|....*....|....*....|....*..
gi 2004286192 1852 AQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFS 1888
Cdd:cd16426 115 GQLAQQYLQRAENIPPTITVNAGTRVNIVVARDVDLP 151
|
|
| VirB10_subf |
NF041422 |
VirB10/TraB/TrbI family type IV secretion system protein; |
1687-1895 |
4.23e-30 |
|
VirB10/TraB/TrbI family type IV secretion system protein;
Pssm-ID: 469313 Cd Length: 404 Bit Score: 125.13 E-value: 4.23e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1687 DPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS--VKGGtpiMTRLMIVFTKAIT 1764
Cdd:NF041422 210 DPDLYIPENTYIPCSLDRRFVSDVAGKISCTISEDVYSASGHVKLIPKGTTARGVYKTgtLKHG---QGRMFIIWTELRT 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1765 PD--GVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPiialdkliGLGKGRSERTpefNYAlgq 1842
Cdd:NF041422 287 PEppYLDIPLVDTQAAGQLGEAGIDGWIDTHFWERFGNALMLSTVQDVAAAAS--------GSAPGKDRNT---DYT--- 352
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2004286192 1843 aiNGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKI 1895
Cdd:NF041422 353 --ENSRQATAEMAKTALENSINIPPTLYKNQGDIIGLITGQDIDFSSIYQLRM 403
|
|
| PRK13855 |
PRK13855 |
type IV secretion system protein VirB10; Provisional |
1688-1900 |
3.05e-29 |
|
type IV secretion system protein VirB10; Provisional
Pssm-ID: 172376 Cd Length: 376 Bit Score: 121.93 E-value: 3.05e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1688 PTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQsvKGGTPIMTRLMIVFTKAITPDG 1767
Cdd:PRK13855 178 PDFMVTQGTIIPCILQTAIDTNLAGYVKCVLPQDIRGTTNNVVLLDRGTTVVGEIQ--RGLQQGDARVFVLWDRAETPDH 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1768 VIIPLAnAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPIIAldkliglgkGRSERTPEFNyalgqaingS 1847
Cdd:PRK13855 256 AMISLS-SPGADELGRSGLPGTVDNHFWQRFSGAMLLSVVQGAFQAASTYA---------GSSGGGTSFN---------S 316
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2004286192 1848 MQSS-AQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSV 1900
Cdd:PRK13855 317 FQNNgEQTADTALKATINIPPTLKKNQGDTVSIFVARDLDFSGIYQLRMTGGAT 370
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
9-73 |
7.78e-28 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
Pssm-ID: 405299 Cd Length: 65 Bit Score: 107.80 E-value: 7.78e-28
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2004286192 9 ETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSE 73
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEEITDDSNDQ 65
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
139-203 |
7.10e-26 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
Pssm-ID: 405299 Cd Length: 65 Bit Score: 102.41 E-value: 7.10e-26
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2004286192 139 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEETQTQMDSE 203
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEEITDDSNDQ 65
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
269-325 |
1.65e-21 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
Pssm-ID: 405299 Cd Length: 65 Bit Score: 89.70 E-value: 1.65e-21
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2004286192 269 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 325
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 57
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
846-1348 |
5.07e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 78.26 E-value: 5.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 846 KTEAEKKECEKLLTPEARKLLEEAKKSVKAYLDCVSQAKteaEKKECEKLLTPEARKLLEE*AKESVKAYLDcvsqaknE 925
Cdd:PTZ00121 1237 KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAE---EARKADELKKAEEKKKADEAKKAEEKKKAD-------E 1306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 926 AEKKECEKLLTLESKKKLEEAKKSVKayldcvsqaktEAEKKECEKLLTPEAKKLLEQQALDCLKNA--KTEADKKRCVK 1003
Cdd:PTZ00121 1307 AKKKAEEAKKADEAKKKAEEAKKKAD-----------AAKKKAEEAKKAAEAAKAEAEAAADEAEAAeeKAEAAEKKKEE 1375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1004 DLPKDLQKKVLAKESLKAykDCVSKARNEKEKKECEKLLTPEAKKLLEEAKKSVKAyldcvSQAKTEAEKKECEKLLTPE 1083
Cdd:PTZ00121 1376 AKKKADAAKKKAEEKKKA--DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEE-----KKKADEAKKKAEEAKKADE 1448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1084 ARKLLEEAKESVKAYKDCVSKAR-NEKEKKECEKLLTPEAKKLLEQqvldclknAKTEADKKRCVKDLPKDLQKKVLAKE 1162
Cdd:PTZ00121 1449 AKKKAEEAKKAEEAKKKAEEAKKaDEAKKKAEEAKKADEAKKKAEE--------AKKKADEAKKAAEAKKKADEAKKAEE 1520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1163 SVKAyldcvSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYK----DCLSQARNEEERRACEKLLTPEARKLLEQEVK 1238
Cdd:PTZ00121 1521 AKKA-----DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeekKKAEEAKKAEEDKNMALRKAEEAKKAEEARIE 1595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1239 KSIKAYLDCVSRARNEKEKKECEKLLTPEARKFL-AKQVLNCLEKAGNEEERKAclKNLPKDLQENILAKESLKAY---- 1313
Cdd:PTZ00121 1596 EVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEeEKKKVEQLKKKEAEEKKKA--EELKKAEEENKIKAAEEAKKaeed 1673
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 2004286192 1314 KDCLSQARNEEE----------RRACEKLLTPEARKLLEQEVKKS 1348
Cdd:PTZ00121 1674 KKKAEEAKKAEEdekkaaealkKEAEEAKKAEELKKKEAEEKKKA 1718
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
386-1157 |
1.75e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 76.72 E-value: 1.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 386 NDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECIsngGNYEECLKLIKDKKLQD 465
Cdd:PTZ00121 1038 NDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAF---GKAEEAKKTETGKAEEA 1114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 466 QMKKtlEAYNDCIKNAKTEEERiKCLDLIKDENLKKSLlNQQKVQVALDCLKNAKTDEERN-ECLKLINDPEIREKFRKE 544
Cdd:PTZ00121 1115 RKAE--EAKKKAEDARKAEEAR-KAEDARKAEEARKAE-DAKRVEIARKAEDARKAEEARKaEDAKKAEAARKAEEVRKA 1190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 545 LELQKELQ----EYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQQALDCLKNAKTDEERNEclknipQDLQKELLADMSV 620
Cdd:PTZ00121 1191 EELRKAEDarkaEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNN------EEIRKFEEARMAH 1264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 621 KAYKDCVSKArneKEKQECEKLLTPEARKKLEQqvldclknAKTDEERKKcLKDLPKDLQSDILAKESLKAYKDCVSQAK 700
Cdd:PTZ00121 1265 FARRQAAIKA---EEARKADELKKAEEKKKADE--------AKKAEEKKK-ADEAKKKAEEAKKADEAKKKAEEAKKKAD 1332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 701 tEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQA--KTEAEKKECEKLltpEAKKKLEEAKKSVKAYLDCVSRARN 778
Cdd:PTZ00121 1333 -AAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAekKKEEAKKKADAA---KKKAEEKKKADEAKKKAEEDKKKAD 1408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 779 EKEKKECEKLLTPEAKKLLEQQALdcLKNAKTDKERKKCLKDLPKDLQKKVLAKESVKAyldcvsqaKTEAEKKECEKLL 858
Cdd:PTZ00121 1409 ELKKAAAAKKKADEAKKKAEEKKK--ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK--------AEEAKKADEAKKK 1478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 859 TPEARKLLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEE*AKESVKAYLDCVSQA---KNEAEKKECEKLL 935
Cdd:PTZ00121 1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAeekKKADELKKAEELK 1558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 936 TLESKKKLEEAKKSVKAYLDCVSQAKteaEKKECEKLLTPEAKKLLEQQALDCLKNAKTEADKKRCVKDLPKDLQKKVLA 1015
Cdd:PTZ00121 1559 KAEEKKKAEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKV 1635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1016 KESLKAYKDCVSKARNEKEKKECEKLLTPEAKKLLEEAKKSVKayldcvSQAKTEAEKKECEKLLTPEARKlLEEAKESV 1095
Cdd:PTZ00121 1636 EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE------EAKKAEEDEKKAAEALKKEAEE-AKKAEELK 1708
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2004286192 1096 KAYKDCVSKARNEKEKKECEKLLTPEAKKLLEQQVLDClKNAKTEADKKRCVKDLPKDLQKK 1157
Cdd:PTZ00121 1709 KKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA-EEAKKDEEEKKKIAHLKKEEEKK 1769
|
|
| PRK13881 |
PRK13881 |
conjugal transfer protein TrbI; Provisional |
1701-1891 |
1.25e-08 |
|
conjugal transfer protein TrbI; Provisional
Pssm-ID: 237541 Cd Length: 472 Bit Score: 59.79 E-value: 1.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1701 TLTSKVDATLTGIVSGVVAKDVWNM-NGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGVIIPLANAQAA 1778
Cdd:PRK13881 288 TLISGINSDLPGQIMAQVSQNVYDTaTGKHLLIPQGSRLVGSYSSdVAYG---QARVLVAWQRIVFPDGKAMDIGAMPGA 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1779 GMLGEAGVDGYVNNHFMKRIGFAVIASVVnsflqTAPiialdklIGLGKGRSERTPEFNY-----ALGQAINgsmQSSAQ 1853
Cdd:PRK13881 365 DSAGYAGFRDQVNNHYVRIFGSAFLMSGV-----TAG-------ITYSQDQNQNNNGYGQptassALSEALG---QQLGQ 429
|
170 180 190
....*....|....*....|....*....|....*...
gi 2004286192 1854 MSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVY 1891
Cdd:PRK13881 430 VTAQLIAKNLNIAPTLEIRPGYRFNVIVTKDMTFSKPY 467
|
|
| IcmE |
cd16431 |
DotG/IcmE is a homolog of VirB10 which forms part of core complex in Type IV secretion system; ... |
1734-1885 |
2.02e-08 |
|
DotG/IcmE is a homolog of VirB10 which forms part of core complex in Type IV secretion system; This family contains DotG/IcmE (VirB10 homolog) and a component of the type IV secretion system (T4SS), and similar proteins. The Dot/Icm system is a T4SS found in the pathogens Legionella and Coxiella and the conjugative apparatus of IncI plasmids; T4SS is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. Similar to T4SS VirB/D components, the Legionella Dot/Icm secretion apparatus contains a critical five-protein sub-assembly that forms the membrane-spanning 'core-complex' (CC), around which all other components assemble. This transmembrane connection is mediated by protein dimer pairs consisting of two inner membrane proteins, DotF and DotG, each independently associating with DotH/DotC/DotD in the outer membrane.
Pssm-ID: 319757 Cd Length: 179 Bit Score: 56.05 E-value: 2.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1734 KGTKVYGNYQSVKggtpimTRLMIVFTKAITPDGVIIPLaNAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVV----NS 1809
Cdd:cd16431 34 KGARLIGSFERSG------DGVVITFTTMVLPGGKSYPI-DAYALDDRTLSAVASDVDNHYLSRYGLPAAAAFLqglgQA 106
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2004286192 1810 FLQTAPIIAldkLIGLGKGRSER-TPEFNYALGQAINGSMQssaQMSnQILGQLMNIPPSFYKNEGDSIKILTMDDI 1885
Cdd:cd16431 107 YQQAGTTTT---STSGGTVTVTTgTPDGKQAAGAAAGGVGQ---QLG-QVLAQDANRPPTVTVPAGTPIGILFMSDV 176
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
17-331 |
4.13e-07 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 55.30 E-value: 4.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 17 DSPQDLSNEEATEANhfenllkESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSEGNETSESSNGSLADklfkkarkl 96
Cdd:NF033609 568 DSGSDSSNSDSGSDS-------GSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSA--------- 631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 97 vdnkkpftQQKNLDEETQELNEEDDQENNEYQEETQTDlIDDETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDH 176
Cdd:NF033609 632 --------SDSDSASDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 702
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 177 HLDNPTETQTNFDGDKSEETQTQMDSEGNETSESSNGSLADklfKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNE 256
Cdd:NF033609 703 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD---SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 779
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2004286192 257 YQEETQTDlIDDETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEEITDDSN 331
Cdd:NF033609 780 SDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 853
|
|
| PRK13831 |
PRK13831 |
conjugal transfer protein TrbI; Provisional |
1688-1891 |
4.24e-07 |
|
conjugal transfer protein TrbI; Provisional
Pssm-ID: 172358 [Multi-domain] Cd Length: 432 Bit Score: 54.74 E-value: 4.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1688 PTFVLAQYTPIEITLTSKVDATL-TGIVSGV-------VAKDVWN-MNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMI 1757
Cdd:PRK13831 233 PNRVVPQQSPYELKRGSVIPATLiTGINSDLpgritaqVSQNVYDsATGHRLLIPQGTKLFGRYDSkVSFG---QSRVLV 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 1758 VFTKAITPDGviiplANAQAAGMlgeAGVD--GY------VNNHFMKRIGFAVIasvvnsflqtapiIALdklIGLGKGR 1829
Cdd:PRK13831 310 VWTDIIFPNG-----STLQIGGM---AGTDaeGYggfkdkVDRHYLRTFGSAIL-------------IAL---IGTGIDM 365
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2004286192 1830 SerTPEFNYALGQ------AINGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVY 1891
Cdd:PRK13831 366 A--VPESSTLATQdtasdaARRNFAETFGRVAERTISKNLNVQPTLEIRPGYKFNVLVDQDIVFPGAY 431
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
9-214 |
2.59e-06 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 52.60 E-value: 2.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 9 ETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSEGNETSESSNGSLADK 88
Cdd:NF033609 665 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 89 LfKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDDETSkKTQQHSPQDLSNEEATEANHFENLLK 168
Cdd:NF033609 745 D-SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDSDSDSDSDSDSDS 822
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2004286192 169 ESKESSDHHLDNPTETQTNFDGDKSEETQTQMDSEGNETSESSNGS 214
Cdd:NF033609 823 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGS 868
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
9-266 |
3.12e-06 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 52.60 E-value: 3.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 9 ETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSEGNETSESSNGSLADk 88
Cdd:NF033609 659 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD- 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 89 lfkkarKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDlIDDETSKKTQQHSPQDLSNEEATEANHFENLLK 168
Cdd:NF033609 738 ------SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 810
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 169 ESKESSDHHLDNPTETQTNFDGDKSEETQTQMDSEGNETSESSNGSLADKLFKKARKLVDNKKPFTQQKNLDEETQELNE 248
Cdd:NF033609 811 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPPNSPKNGTNASNKNEA 890
|
250 260
....*....|....*....|.
gi 2004286192 249 EDDQE---NNEYQEETQTDLI 266
Cdd:NF033609 891 KDSKEplpDTGSEDEANTSLI 911
|
|
| PRK08581 |
PRK08581 |
amidase domain-containing protein; |
21-347 |
4.12e-06 |
|
amidase domain-containing protein;
Pssm-ID: 236304 [Multi-domain] Cd Length: 619 Bit Score: 51.71 E-value: 4.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 21 DLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSEGNETSESSN--GSLADKLFKKARKLVD 98
Cdd:PRK08581 29 DPQKDSTAKTTSHDSKKSNDDETSKDTSSKDTDKADNNNTSNQDNNDKKFSTIDSSTSDSNNiiDFIYKNLPQTNINQLL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 99 NKKPFTQQKNLDEETQEL--NEEDDQENNEYQEETQTDLIDDETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDH 176
Cdd:PRK08581 109 TKNKYDDNYSLTTLIQNLfnLNSDISDYEQPRNSEKSTNDSNKNSDSSIKNDTDTQSSKQDKADNQKAPSSNNTKPSTSN 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 177 hlDNPTETQTNFDGDKSEETQTQMDSeGNETSESSNGSLADKLfkkarklvdnkkpftqqknLDEETQELNEEDDQENNE 256
Cdd:PRK08581 189 --KQPNSPKPTQPNQSNSQPASDDTA-NQKSSSKDNQSMSDSA-------------------LDSILDQYSEDAKKTQKD 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 257 YQEETQTDliddeTSKKTQQHSPQDLSNEE----ATEANHFENLLKESKESSDHHLDNPTETQTNfDGDKSEEITDDSND 332
Cdd:PRK08581 247 YASQSKKD-----KTETSNTKNPQLPTQDElkhkSKPAQSFENDVNQSNTRSTSLFETGPSLSNN-DDSGSFNVVDSKDT 320
|
330
....*....|....*.
gi 2004286192 333 QEIIKG-SKKKYIIGG 347
Cdd:PRK08581 321 RQFIKSiAKDAHRIGQ 336
|
|
| PTZ00341 |
PTZ00341 |
Ring-infected erythrocyte surface antigen; Provisional |
12-260 |
9.58e-06 |
|
Ring-infected erythrocyte surface antigen; Provisional
Pssm-ID: 173534 [Multi-domain] Cd Length: 1136 Bit Score: 50.94 E-value: 9.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 12 KKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSEGN---ETSESSNGSLADK 88
Cdd:PTZ00341 903 KKAKKKDAKDLSGNIAHEINLINKELKNQNENVPEHLKEHAEANIEEDAEENVEEDAEENVEENveeNVEENVEENVEEN 982
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 89 LFKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDDETSKKTQQHSPQdlsNEEATEANHFENlLK 168
Cdd:PTZ00341 983 VEENVEENVEENVEENVEENIEENVEENVEENIEENVEEYDEENVEEVEENVEEYDEENVEE---IEENAEENVEEN-IE 1058
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 169 ESKESSDHhlDNPTETQTNFDGDKSEETQTQMDSEGNETSESSNGSLADKLFKKArklvdnkkpftqQKNLDEETQELNE 248
Cdd:PTZ00341 1059 ENIEEYDE--ENVEEIEENIEENIEENVEENVEENVEEIEENVEENVEENAEENA------------EENAEENAEEYDD 1124
|
250
....*....|..
gi 2004286192 249 EDDQENNEYQEE 260
Cdd:PTZ00341 1125 ENPEEHNEEYDE 1136
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
807-1009 |
1.64e-04 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 46.34 E-value: 1.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 807 NAKTDKERKKCLKDLPKDLQKKVLA-KESVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEEAKKSVKAyldcVSQAKT 885
Cdd:PRK09510 74 AKRAEEQRKKKEQQQAEELQQKQAAeQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAA----AAKAKA 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 886 EAEKKECE---KLLTPEARKLLEE*AKESVKAyldcvsQAKNEAEKKECEKLLTLESKKKLEEAKKSVKAyldcVSQAKT 962
Cdd:PRK09510 150 EAEAKRAAaaaKKAAAEAKKKAEAEAAKKAAA------EAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAA----EAKKKA 219
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2004286192 963 EAEKKECEKLLTPEAKKLLEQQALDCLKNAKTEADKKRCVKDLPKDL 1009
Cdd:PRK09510 220 AAEAKAAAAKAAAEAKAAAEKAAAAKAAEKAAAAKAAAEVDDLFGGL 266
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
1204-1235 |
2.04e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 40.22 E-value: 2.04e-04
10 20 30
....*....|....*....|....*....|..
gi 2004286192 1204 AYKDCLSQARNEEERRACEKLLTPEARKLLEQ 1235
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
1312-1343 |
2.04e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 40.22 E-value: 2.04e-04
10 20 30
....*....|....*....|....*....|..
gi 2004286192 1312 AYKDCLSQARNEEERRACEKLLTPEARKLLEQ 1343
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
790-970 |
2.64e-04 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 45.22 E-value: 2.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 790 TPEAKKLLEQQALDCLKNAKTDKERKKCLKDLPKDLQKKVLAKESVKAYLDCVSQAKTEAEKKECEKLLTPEA---RKLL 866
Cdd:TIGR02794 66 EQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAeaeRKAK 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 867 EEAKKsvKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEE*AKESVKAYldcVSQAKNEAEKKECEKlltlESKKKLEEA 946
Cdd:TIGR02794 146 EEAAK--QAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAE---EAKAKAEAAKAKAAA----EAAAKAEAE 216
|
170 180
....*....|....*....|....
gi 2004286192 947 KKsvkayldcvSQAKTEAEKKECE 970
Cdd:TIGR02794 217 AA---------AAAAAEAERKADE 231
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
622-653 |
4.51e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 39.45 E-value: 4.51e-04
10 20 30
....*....|....*....|....*....|..
gi 2004286192 622 AYKDCVSKARNEKEKQECEKLLTPEARKKLEQ 653
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
553-584 |
6.62e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 38.68 E-value: 6.62e-04
10 20 30
....*....|....*....|....*....|..
gi 2004286192 553 EYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQ 584
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
109-942 |
7.90e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 44.58 E-value: 7.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 109 LDEETQELNEEDDQENNEYQEETQTDLIDDETSKKTQQHSpQDLSNEEATEANHFENLLKESKESSDhhldnpTETQTNF 188
Cdd:pfam02463 200 LKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERI-DLLQELLRDEQEEIESSKQEIEKEEE------KLAQVLK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 189 DGDKSEETQTQMDSEGNETSessngSLADKLFKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDD 268
Cdd:pfam02463 273 ENKEEEKEKKLQEEELKLLA-----KEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKEL 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 269 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDH-----HLDNPTETQTNFDGDKSEEITDDSNDQEIIKGSKKKY 343
Cdd:pfam02463 348 EIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERlssaaKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKE 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 344 IIGGIVVAVLIVIILFSRsifhyfmpLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTL 423
Cdd:pfam02463 428 ELEILEEEEESIELKQGK--------LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERS 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 424 YNYLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSL 503
Cdd:pfam02463 500 QKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARK 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 504 LNQQKVQVALDCLKNAKtdEERNECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEaEKNKCLKGLSKEAIERLK 583
Cdd:pfam02463 580 LRLLIPKLKLPLKSIAV--LEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK-ESAKAKESGLRKGVSLEE 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 584 QQALDCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKDCVSKARNEKEKQECEKLLTPEARKKLEQQVLDCLKNAK 663
Cdd:pfam02463 657 GLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINE 736
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 664 TDEERKKCLKDLPKDLQSDILAKESLKAYKDCVSQAKTEAEKKEcekllTPEAKKLLEEEAKESVKAYLDCVSQAKTEAE 743
Cdd:pfam02463 737 ELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEER-----EKTEKLKVEEEKEEKLKAQEEELRALEEELK 811
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 744 KKECEKLLTPEAKKKLEEAKKSVKAYLdcvsrARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTDKERKKCLKDLPK 823
Cdd:pfam02463 812 EEAELLEEEQLLIEQEEKIKEEELEEL-----ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2004286192 824 DLQKKVLAKESVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKL 903
Cdd:pfam02463 887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966
|
810 820 830
....*....|....*....|....*....|....*....
gi 2004286192 904 LEE*AKESVKAYLDCVSQAKNEAEKKECEKLLTLESKKK 942
Cdd:pfam02463 967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKK 1005
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
952-983 |
9.34e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 38.30 E-value: 9.34e-04
10 20 30
....*....|....*....|....*....|..
gi 2004286192 952 AYLDCVSQAKTEAEKKECEKLLTPEAKKLLEQ 983
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
691-722 |
1.06e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 38.30 E-value: 1.06e-03
10 20 30
....*....|....*....|....*....|..
gi 2004286192 691 AYKDCVSQAKTEAEKKECEKLLTPEAKKLLEE 722
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
837-868 |
1.45e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 37.91 E-value: 1.45e-03
10 20 30
....*....|....*....|....*....|..
gi 2004286192 837 AYLDCVSQAKTEAEKKECEKLLTPEARKLLEE 868
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
875-906 |
1.45e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 37.91 E-value: 1.45e-03
10 20 30
....*....|....*....|....*....|..
gi 2004286192 875 AYLDCVSQAKTEAEKKECEKLLTPEARKLLEE 906
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
1059-1090 |
1.45e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 37.91 E-value: 1.45e-03
10 20 30
....*....|....*....|....*....|..
gi 2004286192 1059 AYLDCVSQAKTEAEKKECEKLLTPEARKLLEE 1090
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
585-615 |
1.57e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 37.91 E-value: 1.57e-03
10 20 30
....*....|....*....|....*....|.
gi 2004286192 585 QALDCLKNAKTDEERNECLKNIPQDLQKELL 615
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLL 31
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
800-830 |
7.97e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 35.60 E-value: 7.97e-03
10 20 30
....*....|....*....|....*....|.
gi 2004286192 800 QALDCLKNAKTDKERKKCLKDLPKDLQKKVL 830
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLL 31
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
1275-1305 |
8.71e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 35.60 E-value: 8.71e-03
10 20 30
....*....|....*....|....*....|.
gi 2004286192 1275 QVLNCLEKAGNEEERKACLKNLPKDLQENIL 1305
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLL 31
|
|
|