NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1998552281|gb|QSL64664|]
View 

hypothetical protein MERGE_001966 [Pneumocystis wakefieldiae]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SHNi-TPR pfam10516
SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted ...
 191-228 9.92e-14

SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted form of TPR repeat.


:

Pssm-ID: 402238 [Multi-domain]  Cd Length: 38  Bit Score: 65.16  E-value: 9.92e-14
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1998552281 191 ADTYDLLGEISLENENFQQALADFQSSLDLKTKIYPLE 228
Cdd:pfam10516   1 ADVYDLLGEISLENENFPQAVTDLRKALELREELLPPE 38
ODC_AZ super family cl03448
Ornithine decarboxylase antizyme; This family consists of ornithine decarboxylase antizyme ...
 490-560 2.03e-06

Ornithine decarboxylase antizyme; This family consists of ornithine decarboxylase antizyme proteins. The polyamine biosynthetic enzyme ornithine decarboxylase (ODC) is degraded by the 26 S proteasome via a ubiquitin-independent pathway. Its degradation is greatly accelerated by association with the polyamine-induced regulatory protein antizyme 1 (AZ1).


The actual alignment was detected with superfamily member pfam02100:

Pssm-ID: 460445  Cd Length: 111  Bit Score: 46.88  E-value: 2.03e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1998552281 490 RGVTTFSKNERSIYI-IGDICNKPFLKQRLVAIIDFASTYLFCSKLFIRI-RKLSSGLESLVKGLIWIGFRIV 560
Cdd:pfam02100  14 RGFVAEDGGERTLFVfFDDGVLGRDLKEGLMALLELAEEPLGCSHVVICFdRSRPDRAKSLVRTLGWVGFELT 86
NlpI super family cl34822
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
163-264 3.08e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG4785:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.37  E-value: 3.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998552281 163 ERGVCGADLEDQKAefAEEKF---IKIEKKLADTYDLLGEISLENENFQQALADFQSSLDLKTKiYPlesslisEAHYKL 239
Cdd:COG4785    78 ERGVAYDSLGDYDL--AIADFdqaLELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPD-YA-------YAYLNR 147

                          90       100
                  ....*....|....*....|....*
gi 1998552281 240 ALAFEFSQESDLrerAIEHIHWAIK 264
Cdd:COG4785   148 GIALYYLGRYEL---AIADLEKALE 169
 
Name Accession Description Interval E-value
SHNi-TPR pfam10516
SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted ...
 191-228 9.92e-14

SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted form of TPR repeat.


Pssm-ID: 402238 [Multi-domain]  Cd Length: 38  Bit Score: 65.16  E-value: 9.92e-14
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1998552281 191 ADTYDLLGEISLENENFQQALADFQSSLDLKTKIYPLE 228
Cdd:pfam10516   1 ADVYDLLGEISLENENFPQAVTDLRKALELREELLPPE 38
ODC_AZ pfam02100
Ornithine decarboxylase antizyme; This family consists of ornithine decarboxylase antizyme ...
 490-560 2.03e-06

Ornithine decarboxylase antizyme; This family consists of ornithine decarboxylase antizyme proteins. The polyamine biosynthetic enzyme ornithine decarboxylase (ODC) is degraded by the 26 S proteasome via a ubiquitin-independent pathway. Its degradation is greatly accelerated by association with the polyamine-induced regulatory protein antizyme 1 (AZ1).


Pssm-ID: 460445  Cd Length: 111  Bit Score: 46.88  E-value: 2.03e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1998552281 490 RGVTTFSKNERSIYI-IGDICNKPFLKQRLVAIIDFASTYLFCSKLFIRI-RKLSSGLESLVKGLIWIGFRIV 560
Cdd:pfam02100  14 RGFVAEDGGERTLFVfFDDGVLGRDLKEGLMALLELAEEPLGCSHVVICFdRSRPDRAKSLVRTLGWVGFELT 86
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
163-264 3.08e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.37  E-value: 3.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998552281 163 ERGVCGADLEDQKAefAEEKF---IKIEKKLADTYDLLGEISLENENFQQALADFQSSLDLKTKiYPlesslisEAHYKL 239
Cdd:COG4785    78 ERGVAYDSLGDYDL--AIADFdqaLELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPD-YA-------YAYLNR 147

                          90       100
                  ....*....|....*....|....*
gi 1998552281 240 ALAFEFSQESDLrerAIEHIHWAIK 264
Cdd:COG4785   148 GIALYYLGRYEL---AIADLEKALE 169
 
Name Accession Description Interval E-value
SHNi-TPR pfam10516
SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted ...
 191-228 9.92e-14

SHNi-TPR; SHNi-TPR family members contain a reiterated sequence motif that is an interrupted form of TPR repeat.


Pssm-ID: 402238 [Multi-domain]  Cd Length: 38  Bit Score: 65.16  E-value: 9.92e-14
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1998552281 191 ADTYDLLGEISLENENFQQALADFQSSLDLKTKIYPLE 228
Cdd:pfam10516   1 ADVYDLLGEISLENENFPQAVTDLRKALELREELLPPE 38
ODC_AZ pfam02100
Ornithine decarboxylase antizyme; This family consists of ornithine decarboxylase antizyme ...
 490-560 2.03e-06

Ornithine decarboxylase antizyme; This family consists of ornithine decarboxylase antizyme proteins. The polyamine biosynthetic enzyme ornithine decarboxylase (ODC) is degraded by the 26 S proteasome via a ubiquitin-independent pathway. Its degradation is greatly accelerated by association with the polyamine-induced regulatory protein antizyme 1 (AZ1).


Pssm-ID: 460445  Cd Length: 111  Bit Score: 46.88  E-value: 2.03e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1998552281 490 RGVTTFSKNERSIYI-IGDICNKPFLKQRLVAIIDFASTYLFCSKLFIRI-RKLSSGLESLVKGLIWIGFRIV 560
Cdd:pfam02100  14 RGFVAEDGGERTLFVfFDDGVLGRDLKEGLMALLELAEEPLGCSHVVICFdRSRPDRAKSLVRTLGWVGFELT 86
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
163-264 3.08e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.37  E-value: 3.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998552281 163 ERGVCGADLEDQKAefAEEKF---IKIEKKLADTYDLLGEISLENENFQQALADFQSSLDLKTKiYPlesslisEAHYKL 239
Cdd:COG4785    78 ERGVAYDSLGDYDL--AIADFdqaLELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPD-YA-------YAYLNR 147

                          90       100
                  ....*....|....*....|....*
gi 1998552281 240 ALAFEFSQESDLrerAIEHIHWAIK 264
Cdd:COG4785   148 GIALYYLGRYEL---AIADLEKALE 169
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
147-313 1.21e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.76  E-value: 1.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998552281 147 EALDfsrvLYEKMLDME---------RGVCGADLED-QKAEFAEEKFIKIEKKLADTYDLLGEISLENENFQQALADFQS 216
Cdd:COG0457    60 EALA----DYEQALELDpddaealnnLGLALQALGRyEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYER 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998552281 217 SLDLKTKIYplesslisEAHYKLALAFEFSQEsdlRERAIEHIHWAIKSLEKRLEIEQKSEKGKEKQGKEESEILDMLLE 296
Cdd:COG0457   136 ALELDPDDA--------DALYNLGIALEKLGR---YEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALE 204

                         170
                  ....*....|....*..
gi 1998552281 297 LRQKIKELEKIPEKTAI 313
Cdd:COG0457   205 QALRKKLAILTLAALAE 221
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
164-264 1.34e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.76  E-value: 1.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998552281 164 RGVCGADLED-QKAEFAEEKFIKIEKKLADTYDLLGEISLENENFQQALADFQSSLDLKTKIYplesslisEAHYKLALA 242
Cdd:COG0457    14 LGLAYRRLGRyEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDA--------EALNNLGLA 85

                          90       100
                  ....*....|....*....|..
gi 1998552281 243 FEFSQESdlrERAIEHIHWAIK 264
Cdd:COG0457    86 LQALGRY---EEALEDYDKALE 104
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
147-264 4.79e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.83  E-value: 4.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998552281 147 EALDfsrvLYEKMLDME---------RGVCGADLED-QKAEFAEEKFIKIEKKLADTYDLLGEISLENENFQQALADFQS 216
Cdd:COG0457    26 EAIE----DYEKALELDpddaealynLGLAYLRLGRyEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDK 101

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1998552281 217 SLDLKTKIYplesslisEAHYKLALAFEFSQEsdlRERAIEHIHWAIK 264
Cdd:COG0457   102 ALELDPDDA--------EALYNLGLALLELGR---YDEAIEAYERALE 138
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
184-264 8.98e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.06  E-value: 8.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998552281 184 IKIEKKLADTYDLLGEISLENENFQQALADFQSSLDLKTKIYplesslisEAHYKLALAFEfsqESDLRERAIEHIHWAI 263
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDA--------EALYNLGLAYL---RLGRYEEALADYEQAL 69


                  .
gi 1998552281 264 K 264
Cdd:COG0457    70 E 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH