|
Name |
Accession |
Description |
Interval |
E-value |
| PQQ_enz_alc_DH |
TIGR03075 |
PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic ... |
27-564 |
0e+00 |
|
PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Genes in this family often are found adjacent to the PQQ biosynthesis genes themselves. An unusual, strained disulfide bond between adjacent Cys residues contributes to PQQ-binding, as does a Trp residue that is part of a PQQ enzyme repeat (see pfam01011). Characterized members include the dehydrogenase subunit of a membrane-anchored, three subunit alcohol (ethanol) dehydrogenase of Gluconobacter suboxydans, a homodimeric ethanol dehydrogenase in Pseudomonas aeruginosa, and the large subunit of an alpha2/beta2 heterotetrameric methanol dehydrogenase in Methylobacterium extorquens.
Pssm-ID: 274419 [Multi-domain] Cd Length: 527 Bit Score: 869.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 27 AAAKDVTDADILNDAKTPGDVVSFGLGTQGQRFSQLAAVNTGTVKNLVPAWSMSFGgeKQRGQESQPVIHDGKMFVTASY 106
Cdd:TIGR03075 1 AAAAAVTNEDLLNDAKDPSDWLTYGGGYAGQRYSPLDQINTDNVKKLQPAWTFSLG--KQRGQESQPLVVDGVMYVTTSY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 107 SRLFAIDAKTGKKLWKYEHRLPDGIMP--CCDVINRGAALYGNLVIFGTLDAQLVALNKDTGKVVWKEKVDDYAAGYSIT 184
Cdd:TIGR03075 79 SRVYALDAKTGKILWKYDPKLPDDIIPvmCCDVVNRGAALYDGKVFFGTLDARLVALDAKTGKVVWSKKNGDYKKGYTIT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 185 AAPIIAKGKLITGVSGGEFGIVGRIDARDPLTGKLVWTRPTVEGHMGYVvdkdgNKKENGISGTANA-TWSGDLWKTGGA 263
Cdd:TIGR03075 159 AAPLVVKGKVITGISGGEFGVRGYVTAYDAKTGKLVWRRYTVPGDMGYL-----KKTGKPVGGDPGAkTWPGDAWKTGGG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 264 ATWNGATYDPETNLIFAGTGNPAPWNSHLRPGDNLFSSSTVAIDADTGKIVWHYQNTPHDGWDFDGVNEFVSFDFKdpKT 343
Cdd:TIGR03075 234 ATWGTGSYDPETNLIYFGTGNPAPWNSHLRPGDNLYTSSIVARDPDTGKIKWHYQTTPHDEWDYDGVNEMILFDLK--KD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 344 GKVVKAGGKADRNGFFFVNDRTNGKLLNAFPFVNKITWAKSIDLKTGRPVYDDENRPGDptagdGKKGKTVFSAPSFLGG 423
Cdd:TIGR03075 312 GKPRKLLAHADRNGFFYVLDRTNGKLLSAEPFVDKVNWATGVDLKTGRPIEVPEARSTD-----GKKGKPVEVCPGFLGG 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 424 KNQQQIAYNPQTGLFYVPANEWGMDIWNEPVAYKKGAAYLGAGFTIKPLHEDYIGVMRAVDPVSGKVVWENKNYAPLWGG 503
Cdd:TIGR03075 387 KNWQPMAYSPKTGLFYVPANHVCMDYWPEKVSYKKGAAYLGAGFTIKPPPDDHIGSLIAWDPITGKIVWEHKEDFPLWGG 466
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1980235597 504 ALTTAGGLTFYGTPEGYLKAVDAKTGKELWSFQTGTGIVAPPVTWEQDGEQMIAVTTGWGG 564
Cdd:TIGR03075 467 VLATAGDLVFTGTLEGYFKAFDAKTGEELWKFKTGSGIVGPPVTYEQDGKQYVAVLSGWGG 527
|
|
| PQQ_ADH_I |
cd10277 |
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ... |
37-591 |
0e+00 |
|
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.
Pssm-ID: 199835 [Multi-domain] Cd Length: 529 Bit Score: 855.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 37 ILNDAKTPGDVVSFGLGTQGQRFSQLAAVNTGTVKNLVPAWSMSFGGeKQRGQESQPVIHDGKMFVTASYSRLFAIDAKT 116
Cdd:cd10277 1 LLNDAKETGNWLTYGRGYNGQRYSPLKQINTDNVKNLVPAWSFSFGG-KQRGQESQPIVNDGVMYVTTSYNRVFAIDAKT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 117 GKKLWKYEHRLPDGIMPCCDVINRGAALYGNLVIFGTLDAQLVALNKDTGKVVWKEKVDDYAAGYSITAAPIIAKGKLIT 196
Cdd:cd10277 80 GKELWKYKHRLPEDIRPCCDVVNRGVALYGDKVYFGTLDAHLVALDAKTGKVVWKKKVADYKAGYSMTLAPLVVKGKVIV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 197 GVSGGEFGIVGRIDARDPLTGKLVWTRPTVEGHMGYVvdkdgnkkengisgtANATWSGDLWKTGGAATWNGATYDPETN 276
Cdd:cd10277 160 GVSGGEFGVRGFIAALDAETGKEVWRTYTVPGPGEPG---------------STDTWPGDAWKTGGGATWLTGTYDPETN 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 277 LIFAGTGNPAPWNSHLRPGDNLFSSSTVAIDADTGKIVWHYQNTPHDGWDFDGVNEFVSFDFkdPKTGKVVKAGGKADRN 356
Cdd:cd10277 225 LLYWGVGNPAPWNGDLRPGDNLYTSSVLALDPDTGKIKWHYQYTPNDTWDYDGVNEPVLFDY--TKNGKPVKALVHADRN 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 357 GFFFVNDRTNGKLLNAFPFVNKITWAkSIDLKTGRPVYDDENRPGdptagdgKKGKTVFSAPSFLGGKNQQQIAYNPQTG 436
Cdd:cd10277 303 GFFYVLDRTNGKLIWATPFVKKITWA-SIDLKTGRPIYDEDKVPP-------KKGKTVDFCPSFLGGKNWPPMAYSPDTG 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 437 LFYVPANEWGMDIWNEPVAYKKGAAYLGAGFTIKPLHEDYIGVMRAVDPVSGKVVWENKNYAPLWGGALTTAGGLTFYGT 516
Cdd:cd10277 375 LFYVPANHWCMDLTGEPVSYKKGAAYLGAGFTIKPPFEDHIGELQAIDPTTGKKVWEHKTPLPLWGGVLTTAGGLVFTGT 454
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1980235597 517 PEGYLKAVDAKTGKELWSFQTGTGIVAPPVTWEQDGEQMIAVTTGWGGAVPLWGGDVAKRVNYLEQGGSVWVFKL 591
Cdd:cd10277 455 PDGYFRAFDAKTGKELWEFQTGSGIIGPPVTWEVDGKQYVAVLSGWGGAAPLWGGDMAKLLKNVPQGGSLWVFAL 529
|
|
| Gcd |
COG4993 |
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism]; |
43-591 |
0e+00 |
|
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
Pssm-ID: 444017 [Multi-domain] Cd Length: 515 Bit Score: 716.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 43 TPGDVVSFGLGTQGQRFSQLAAVNTGTVKNLVPAWSMSFGGEKQRGQESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWK 122
Cdd:COG4993 1 DPGDWLAYGGDYAGQRYSPLDQINPDNVKKLKVAWTFSTGDLPERGHEATPLVVDGVLYVCTPHNRVFALDAATGKELWR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 123 YEHRLPDGIMpCCDVINRGAALYGNLVIFGTLDAQLVALNKDTGKVVWKEKVDDYAAGYSITAAPIIAKGKLITGVSGGE 202
Cdd:COG4993 81 YDPKLPDDAA-CCDVVNRGVAYYDGRIFLGTLDGRLVALDAKTGKVCWDVKVGDPKKGYTITSAPLVVKDKVIVGGSGGE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 203 FGIVGRIDARDPLTGKLVWTRPTVEGHMGYvvdkdgnkkengisgtANATWS-GDLWKTGGAATWNGATYDPETNLIFAG 281
Cdd:COG4993 160 FGPRGVVRAYDARTGKLVWRFDTIPDPGEP----------------GAETWPpGDTWKRGGGNVWGTMSYDPELGLVYLP 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 282 TGNPAP-WNSHLRPGDNLFSSSTVAIDADTGKIVWHYQNTPHDGWDFDGVNEFVSFDFkdPKTGKVVKAGGKADRNGFFF 360
Cdd:COG4993 224 TGNPAPdWNGGQRPGDNLYSSSIVALDADTGELKWHYQTVPHDLWDYDGPNEPILVDL--PVDGKTRKALVQATKNGFIY 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 361 VNDRTNGKLLNAFPFVNKITWAKSIDLKTGRPVYDdenrpgdPTagdGKKGKTVFSAPSFLGGKNQQQIAYNPQTGLFYV 440
Cdd:COG4993 302 VLDRETGEPLVTQPFVKPPNWATEIDMWGATPIQT-------PP---SLDGKTTLICPGALGGKNWGPAAYDPETGLLYV 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 441 PANEWGMDIWNEPVAYKKGAAYLGAGFTIKPLHEDYIGVMRAVDPVSGKVVWENKNYAPLWGGALTTAGGLTFYGTPEGY 520
Cdd:COG4993 372 PANELCMDYELVPREYQAGAPYLGATLTMYPCPAPPWGTLTAIDLNTGKIVWQVPLGFPNWGGPLATAGGLVFIGTLDGY 451
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1980235597 521 LKAVDAKTGKELWSFQTGTGIVAPPVTWEQDGEQMIAVTTGWGGAVPLWGgdvakrvnYLEQGGSVWVFKL 591
Cdd:COG4993 452 LRAFDAKTGKELWKFRLPSGGQATPMTYEVDGKQYVAVAAGGGGWLGLGL--------YTPQGDYLIAFAL 514
|
|
| PQQ_MDH |
cd10278 |
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ... |
55-591 |
5.61e-177 |
|
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.
Pssm-ID: 199836 [Multi-domain] Cd Length: 553 Bit Score: 512.26 E-value: 5.61e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 55 QGQRFSQLAAVNTGTVKNLVPAWSMSFGgeKQRGQESQPVIHDGKMFVTASY-SRLFAID-AKTGKKLWKYEHRLPDGIM 132
Cdd:cd10278 9 ANTRYSPLAQINKDNVKNLKVAWTFSTG--VLRGHEGAPLVVGDTMYVVTPFpNNVYALDlNDPGKILWKYKPKQDPSAV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 133 P--CCDVINRGAALYGNLVIFGTLDAQLVALNKDTGKVVWKEKVDDYAAGYSITAAPIIAKGKLITGVSGGEFGIVGRID 210
Cdd:cd10278 87 AvaCCDVVNRGLAYADGKIFFNQLDGHLVALDAKTGKEVWKVKNGDPKVGETLTMAPLVVKDKVIVGISGGEFGVRGYVT 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 211 ARDPLTGKLVW----TRPTVEghmgYVVDKDGNKK--ENGISGTANATWSGDLWKTGGAATWNGATYDPETNLIFAGTGN 284
Cdd:cd10278 167 AYDLKTGKLVWraysTGPDKD----VLIGPDFNPFnpHDGGKDLGLSTWPGDAWKIGGGTNWGWYSYDPKLNLVYYGTGN 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 285 PAPWNSHLRPGDNLFSSSTVAIDADTGKIVWHYQNTPHDGWDFDGVNEFVSFDFkdPKTGKVVKAGGKADRNGFFFVNDR 364
Cdd:cd10278 243 PGPWNPTQRPGDNKWSMTIFARDPDTGEAKWAYQMTPHDEWDYDGVNEMILVDQ--TVDGKKRKLLVHFDRNGFVYTLDR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 365 TNGKLLNAFPFVNkITWAKSIDLKTGRPVYDDENRPGDptagdGKKGKTVFsaPSFLGGKNQQQIAYNPQTGLFYVPANE 444
Cdd:cd10278 321 TTGELLSAEKFDP-VNNWKGVDLKTGRPVKDPEKSTHM-----DHNVTDIC--PSAMGGKDQQPSSYSPKTGLFYVPTNH 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 445 WGMDIWNEPVAYKKGAAYLGAGFTIKPLHEDYIGVMRAVDPVSGKVVWENKNYAPLWGGALTTAGGLTFYGTPEGYLKAV 524
Cdd:cd10278 393 LCMDYEPFEVNYTAGQPYVGATLAMYPGPGGHMGQFKAWDPVTGKTKWEIKERFPVWSGTLATAGGLVFYGTLDGWFKAV 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 525 DAKTGKELWSFQTGTGIVAPPVTWEQDGEQMIAVTTGWGG--AVPLWGGD------------VAKRVNYLEQGGSVWVFK 590
Cdd:cd10278 473 DAKTGKLLWKFKLPSGIIGNPITYKHDGKQYVAVLSGVGGwaGVGVAAGLrdptaglgavgaFKDLPNYTQMGGTLYVFS 552
|
.
gi 1980235597 591 L 591
Cdd:cd10278 553 L 553
|
|
| PQQ_ADH_II |
cd10279 |
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of ... |
49-591 |
5.52e-169 |
|
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of monomeric and soluble type II alcohol dehydrogenases utilizes pyrroloquinoline quinone (PQQ) as a cofactor and is related to ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller.
Pssm-ID: 199837 [Multi-domain] Cd Length: 549 Bit Score: 491.77 E-value: 5.52e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 49 SFGLGTQGQRFSQLAAVNTGTVKNLVPAWSMSFGGEkqRGQESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLP 128
Cdd:cd10279 5 SYGRDYDEQRFSPLTQINRSNVGQLGLAWYFDLDTN--RGQEATPLVVDGVMYVSGPWSVVYALDARTGKLLWQYDPEVD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 129 DGIM--PCCDVINRGAALYGNLVIFGTLDAQLVALNKDTGKVVWKEKVDDYAAGYSITAAPIIAKGKLITGVSGGEFGIV 206
Cdd:cd10279 83 RESGrkACCDVVNRGVAVWDGKVFVGTLDGRLIALDAKTGKEVWSVDTIDPRKPYTITGAPRVAKGKVVIGNGGAEFGVR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 207 GRIDARDPLTGKLVWTRPTVEGhmgyvvDKDGNKKENGISGTANATWSGDLWKTGGAAT-WNGATYDPETNLIFAGTGNP 285
Cdd:cd10279 163 GYVSAYDAETGKLVWRFYTVPG------NPAKPFEHASLEAAAATWWTGEWWRTGGGGTvWDSITYDPELDLLYIGTGNG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 286 APWNSHLRP---GDNLFSSSTVAIDADTGKIVWHYQNTPHDGWDFDGVNEFVSFDFK-DPKTGKVVKaggKADRNGFFFV 361
Cdd:cd10279 237 SPWNRKVRSpggGDNLFLSSIVALDADTGRYKWHYQTTPGDTWDYTATQPIILADLEiDGKPRKVLM---HAPKNGFFYV 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 362 NDRTNGKLLNAFPFVnKITWAKSIDLKTGRPVYDDENRpgdptagDGKKGKTVFsaPSFLGGKNQQQIAYNPQTGLFYVP 441
Cdd:cd10279 314 LDRATGKLLSAEPFV-PVNWATGIDLKTGRPIENPEAR-------YTKGPKLVF--PGPLGAHNWHPMSYNPDTGLVYIP 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 442 ANEWGMDIWNEPVAYKK--GAAYLGAGFTIKPLHEDYIGVMR--------AVDPVSGKVVWENKNYAPLWGGALTTAGGL 511
Cdd:cd10279 384 AQEIPAVYEDDPGDFGYnpLGWNTGITPDATPPPAAAKRALRkatrgrlvAWDPVTQKAAWRVEHPGPWNGGVLATAGNL 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 512 TFYGTPEGYLKAVDAKTGKELWSFQTGTGIVAPPVTWEQDGEQMIAVTTGWGGAVPLWGGDVAKRVNYlEQGGSVWVFKL 591
Cdd:cd10279 464 VFQGTADGELAAYDARTGEKLWSFDTGSGIVAAPMTYSVDGEQYVAVLAGWGGAGALSGGPPGAAGKV-QNPGRLLVFKL 542
|
|
| PQQ_DH_like |
cd00216 |
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases ... |
68-590 |
3.24e-153 |
|
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases with pyrroloquinoline quinone (PQQ) as a cofactor, such as ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller, and the family also includes distantly related proteins which are not enzymatically active and do not bind PQQ.
Pssm-ID: 199833 [Multi-domain] Cd Length: 434 Bit Score: 447.44 E-value: 3.24e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 68 GTVKNLVPAWSMSFGGEKQRGQESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPDG-IMPCCDVINRGAALYG 146
Cdd:cd00216 2 DNVFQLTPAWSFSTGDGGNRGSELTPIVVDGVMYATTSFSRVFALDADDGKEIWSYDPALKDGwFEACCDLVNRGVAVWG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 147 NLVIFGTLDAQLVALNKDTGKVVWKEKVDDYAAGYSITAAPIIAKGKLITGVSGGEFGIVGRIDARDPLTGKLVWTRPTV 226
Cdd:cd00216 82 GKVYIGVLDGRVYALNAETGKVAWKVKNADVLGGYTATSAPVVVDGLVIIGSSGDEFGVRGYLTAYDVATGEEKWRFYLV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 227 EGHMGYVVDKDGNkkengISGTANATWSGDLWKTGGAATWNGATYDPETNLIFAGTGNPAPWN--SHLRPGDNLFSSSTV 304
Cdd:cd00216 162 MPDPNLLPGKDST-----VTDRNTPTGDEHTWTSGGGTGWSSAAYDAELNLIYVGGGNPTPWNwgGNRTPGDNLYTSSIV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 305 AIDADTGKIVWHYQNTPHDGWDFDGVNEFVSFDFKDpkTGKVVKAGGKADRNGFFFVNDRTNGKLLNAFPFVNkitwaks 384
Cdd:cd00216 237 AVNADTGEMKWQYQTTPHDAWDYDGDNTPVLADIKV--KGKKVKVLFAPAKNGNFYVLDRRNGELVSARPLVP------- 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 385 idlktgrpvyddenrpgdptagdgkkgktvfsapsflggknqqqIAYNPQTGLFYVPANewgmdiwnepvaykkgaaylg 464
Cdd:cd00216 308 --------------------------------------------DSYDPDRELFYVPAN--------------------- 322
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 465 agftikplhedyiGVMRAVDPVSGKVVWENKNYAPLWGGALTTAGGLTFYGTPEGYLKAVDAKTGKELWSFQTGTGIVAP 544
Cdd:cd00216 323 -------------GRIMALDPVTGVVVWEKSELHPLLGGPLSTAGNLVFVGTSDGYLKAYNADTGEKLWQQKVPSGFQAE 389
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 1980235597 545 PVTWEQDGEQMIAVTTGWGGAVPLWGGdVAKRVNYLEQGGSVWVFK 590
Cdd:cd00216 390 PVTYEVDGEQYVLIQAGGGGAFPLWGG-MADLTRGTQMGGTVVVYK 434
|
|
| PQQ_mGDH |
cd10280 |
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes ... |
49-564 |
7.24e-77 |
|
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes belongs to the dehydrogenase family with pyrroloquinoline quinone (PQQ) as cofactor, and is the only subfamily that is bound to the membrane. Glucose dehydrogenase converts D-glucose to D-glucono-1,5-lactone in a reaction that is coupled with the respiratory chain in the periplasmic oxidation of sugars and alcohols in gram-negative bacteria. Ubiquinone functions as the electron acceptor. The alignment model contains an 8-bladed beta-propeller.
Pssm-ID: 199838 [Multi-domain] Cd Length: 616 Bit Score: 255.58 E-value: 7.24e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 49 SFGLGTQGQRFSQLAAVNTGTVKNLVPAWSMSFGGEKQRGQ-----ESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKY 123
Cdd:cd10280 3 AYGGDPGGTRYSPLDQITPDNVGKLKVAWTYHTGDLPGPDGnegtfEATPLKVGGTLYLCTPHNRVIALDAATGKELWRF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 124 E----HRLPDGIMPCcdvinRGAALY---------GNLVIFGTLDAQLVALNKDTGKVVW----------KEKVDDYAAG 180
Cdd:cd10280 83 DpkagADAAPGHQTC-----RGVSYWedgaaaaacARRIFFGTGDARLIALDARTGKPCPdfgdngvvdlREGLGRVKPG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 181 -YSITAAPIIAKGKLITGVSGGEFGIV----GRIDARDPLTGKLVWTRPTveghmgyvvdkdGNKKENGISGTANATWSg 255
Cdd:cd10280 158 fYSSTSPPTVYGDLVIVGSAVADNQAVdapsGVIRAFDVRTGKLVWAFDT------------IPPPGEAGPDTAGAWYT- 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 256 dlwkTGGAATWNGATYDPETNLIFAGTGNPAP--WNSHlRPGDNLFSSSTVAIDADTGKIVWHYQNTPHDGWDFDGVNEF 333
Cdd:cd10280 225 ----RGGPNVWAGMSADEKLGLVYLPTGSATPdfYGGD-RPGDNLFANSLVALDAATGKRRWHFQTVHHDLWDYDLPAQP 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 334 VSFDFKDPktGKVVKAGGKADRNGFFFVNDRTNGKllnafpfvnkitwaksidlktgrPVYDDENR-------PGDPTA- 405
Cdd:cd10280 300 TLVDVPRD--GKTVPAVAQPTKQGFVFVLDRRTGK-----------------------PLWPVEERpvpqgdvPGERTSp 354
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 406 -----------------GDGKKGKTVFSA---------------------------PSFLGGKNQQQIAYNPQTGLFYVP 441
Cdd:cd10280 355 tqpfptlpppfarqgltEDDMWGATPFDQlacriqfrslryeglftppsldgtlifPGNDGGANWGGAAVDPERGILYVN 434
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 442 ANEWGMDIWNEPVA------YKKGAAYLGAGFTIKPLHEDYIGVMR--------------------AVDPVSGKVVWENK 495
Cdd:cd10280 435 SNRLPFVIQLVPRApgdpagVAGGGEGGGGGGGPSPQAGTPYGVGRgrflsplglpcqappwgtltAIDLNTGKILWQVP 514
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 496 N-----------------YAPLWGGALTTAGGLTFYG-TPEGYLKAVDAKTGKELWSFQTGTGIVAPPVTWEQDGEQMIA 557
Cdd:cd10280 515 LgtvpdlgpkgiplpiptGTPNLGGPVVTAGGLVFIAaTQDNYLRAFDKATGKELWEARLPAGGQATPMTYEVDGKQYVV 594
|
....*..
gi 1980235597 558 VTTGWGG 564
Cdd:cd10280 595 IAAGGHG 601
|
|
| PQQ_membr_DH |
TIGR03074 |
membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; This protein ... |
31-572 |
1.54e-46 |
|
membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Members of this family have several predicted transmembrane helices in the N-terminal region, and include the quinoprotein glucose dehydrogenase (EC 1.1.5.2) of Escherichia coli and the quinate/shikimate dehydrogenase of Acinetobacter sp. ADP1 (EC 1.1.99.25). Sequences closely related except for the absense of the N-terminal hydrophobic region, scoring in the gray zone between the trusted and noise cutoffs, include PQQ-dependent glycerol (EC 1.1.99.22) and and other polyol (sugar alcohol) dehydrogenases.
Pssm-ID: 274418 [Multi-domain] Cd Length: 764 Bit Score: 174.80 E-value: 1.54e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 31 DVTDADILNDAKTPGDVVSFGLGTQGQRFSQLAAVNTGTVKNLVPAWSMSFGGEKQRGQ------ESQPVIHDGKMFVTA 104
Cdd:TIGR03074 122 EVPATAAAAPAVPAGDWAAYGRTQAGQRYSPLDQINPDNVGNLKVAWTYHTGDLKTPDDpgeatfQATPLKVGDTLYLCT 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 105 SYSRLFAIDAKTGKKLWKYEHRLPDGIMP----CcdvinRGAALY------------------GNLVIFGTLDAQLVALN 162
Cdd:TIGR03074 202 PHNKVIALDAATGKEKWKFDPKLKTEADRqhqtC-----RGVSYYdapaaaagpagpaapadcARRIILPTSDARLIALD 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 163 KDTGKVVW----KEKVD-------DYAAGYSITAAPIIAKGKLITG------VSGGEFGivGRIDARDPLTGKLVWTRPT 225
Cdd:TIGR03074 277 ADTGKLCEdfgnNGTVDltagmgpTPPGYYYPTSPPLVAGTTVVIGgrvadnYSTDEPS--GVIRAFDVNTGALVWAWDP 354
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 226 veghmgyvvdkdGNKKENGISGtanatwSGDLWKTGGAATWNGATYDPETNLIFAGTGNPAP--WNSHLRPGDNLFSSST 303
Cdd:TIGR03074 355 ------------GNPDPTAPPA------PGETYTRNSPNSWSVASYDEKLGLVYLPMGNQTPdqWGGDRTPADEKYSSSL 416
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 304 VAIDADTGKIVWHYQNTPHDGWDFDGVNEFVSFDFKDpKTGKVVKAGGKADRNGFFFVNDRTNGKL-------------- 369
Cdd:TIGR03074 417 VALDATTGKERWVFQTVHHDLWDMDVPAQPSLVDLPK-ADGTTVPALVAPTKQGQIYVLDRRTGEPivpveevpvpqgav 495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 370 ---------------LNAFPFVNKITW--------AKSIDLKTGRpvYDDENRPgdPtagdGKKGKTVFsaPSFLGGKNQ 426
Cdd:TIGR03074 496 pgerysptqpfsvltFGPPTLTESDMWgatpfdqlACRIQFKSLR--YEGLYTP--P----SEQGSLVF--PGNLGGFNW 565
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 427 QQIAYNPQTGLFYVPANEWG-------MDIWNEPVA------------YKKGAAYlgaGFTIKPLHEDY--------IGV 479
Cdd:TIGR03074 566 GGVAVDPTRQVMFVNPMRLPfvsqlvpRAPGDEAPSgakgkgtemglnPNKGTPY---AVNMNPFLSPLgipcqappWGY 642
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 480 MRAVDPVSGKVVWENKNYA-------------------PLWGGALTTAGGLTFYG-TPEGYLKAVDAKTGKELWSFQTGT 539
Cdd:TIGR03074 643 MAAIDLKTGKVVWQHPNGTvrdtgpmgipmplpipigvPTLGGPLATAGGLVFIGaTQDNYLRAYDLSTGKELWEARLPA 722
|
650 660 670
....*....|....*....|....*....|....
gi 1980235597 540 GIVAPPVTW-EQDGEQMIAVTTGWGGAVPLWGGD 572
Cdd:TIGR03074 723 GGQATPMTYmGKDGKQYVVIVAGGHGSSGTKRGD 756
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
73-222 |
7.05e-17 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 82.55 E-value: 7.05e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 73 LVPAWSMSFGGEKQRGQES-QPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPdgimpccdvINRGAALYGNLVIF 151
Cdd:COG1520 32 VKQLWSASVGDGVGKGYSRlAPAVAGDRVYAADADGRVAALDAATGKELWRVDLGEP---------LSGGVGADGGLVVV 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1980235597 152 GTLDAQLVALNKDTGKVVWKEKVDDyaagySITAAPIIAKGKLItgVSGGEfgivGRIDARDPLTGKLVWT 222
Cdd:COG1520 103 GTEDGEVIALDADDGEELWRARLSS-----EVLAAPAVAGGRVV--VRTGD----GRVYALDAATGERLWS 162
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
56-237 |
1.31e-15 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 76.29 E-value: 1.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 56 GQRFSQLAAVNTGTVKNLvpaWSMSFGGEKQrgqeSQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPDGIMpcc 135
Cdd:pfam13360 39 ATGGGQLVALDAATGKLL---WRQTLSGEVL----GAPLVAGGRVFVVAGDGSLIALDAADGRRLWSYQRSGEPLAL--- 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 136 dVINRGAALYGNLVIFGTLDAQLVALNKDTGKVVWKEKV------DDYAAGYSITAAPIIAKGKLItgVSGGEfgivGRI 209
Cdd:pfam13360 109 -RSSGSPAVVGDTVVAGFSSGKLVALDPATGKVRWEAPLaaprgtNELERLVDITGTPVVAGGRVF--ASAYQ----GRL 181
|
170 180
....*....|....*....|....*...
gi 1980235597 210 DARDPLTGKLVWTRPtVEGHMGYVVDKD 237
Cdd:pfam13360 182 VAFDAATGRRLWTRE-ISGPNGPILDGD 208
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
77-317 |
7.57e-15 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 76.22 E-value: 7.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 77 WSMSFGGeKQRgQESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEhrLPDGImpccdvINRGAALYGNLVIFGTLDA 156
Cdd:cd10276 62 WETSLSG-KGF-LGGTPAVGNGKIFVGTESGYLYALDAKDGSELWRTE--VSDSQ------LLSPPTYADGKIYVGTGDG 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 157 QLVALNKDTGKVVWKEKVDDYAAGYSITAAPIIAKGKLITGVSGGefgivgRIDARDPLTGKLVWTRPTVEGHMG----Y 232
Cdd:cd10276 132 RLYYCNAETGKVVWNRTSTAPELSLRGGAAPVGAYDVVFVGDGNG------TVVALNTGTGVDIWEFSVSEPRGRtelpR 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 233 VVDKDGNKKENGISGTAnATWSGDLWKtggaatwngatYDPETNLIF------AGTGNPAPWNSHLRPGDNlfSSSTVAI 306
Cdd:cd10276 206 MIDSSVTYVVVGGYLYS-TSYQGYLVA-----------LDFESGQFLwsrkasGGTSTSTDANGRVYVGDG--EGSLYCL 271
|
250
....*....|.
gi 1980235597 307 DADTGKIVWHY 317
Cdd:cd10276 272 DASTGDELWSQ 282
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
93-315 |
1.87e-14 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 73.21 E-value: 1.87e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 93 PVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPDGIMPccdvinrgaALYGNLVIFGTLDAQLVALNKDTGKVVWKE 172
Cdd:pfam13360 29 VAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLGAP---------LVAGGRVFVVAGDGSLIALDAADGRRLWSY 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 173 KVDDYAAGYSITAAPIIAKGKLITGVSGgefgivGRIDARDPLTGKLVW----TRPTVEGHMGYVVDKDGNKKENGisGT 248
Cdd:pfam13360 100 QRSGEPLALRSSGSPAVVGDTVVAGFSS------GKLVALDPATGKVRWeaplAAPRGTNELERLVDITGTPVVAG--GR 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1980235597 249 ANATwSGDlwktGGAATWNGATYDPETNLIFAGTGNPAPwnshlrPGDNLFSSST----VAIDADTGKIVW 315
Cdd:pfam13360 172 VFAS-AYQ----GRLVAFDAATGRRLWTREISGPNGPIL------DGDLLYVVSDdgelYALDRATGAVVW 231
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
68-238 |
4.60e-14 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 74.20 E-value: 4.60e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 68 GTVKNLVPAWSMSFGGEKQRGQES-----QPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPDGIMpccdvinRGA 142
Cdd:TIGR03300 111 GTEKGEVIALDAEDGKELWRAKLSsevlsPPLVANGLVVVRTNDGRLTALDAATGERLWTYSRVTPPLTL-------RGS 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 143 A---LYGNLVIFGTLDAQLVALNKDTGKVVWKEKVdDYAAGYS-------ITAAPIIAKGKLITgvsggeFGIVGRIDAR 212
Cdd:TIGR03300 184 AspvIADGGVLVGFAGGKLVALDLQTGQPLWEQRV-ALPKGRTelerlvdVDGDPVVDGGQVYA------VSYQGRVAAL 256
|
170 180 190
....*....|....*....|....*....|...
gi 1980235597 213 DPLTGKLVWTR-------PTVEGHMGYVVDKDG 238
Cdd:TIGR03300 257 DLRSGRVLWKRdassyqgPAVDDNRLYVTDADG 289
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
91-239 |
4.67e-14 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 74.08 E-value: 4.67e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 91 SQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPDGIMpccdvinRGAA---LYGNLVIFGTLDAQLVALNKDTGK 167
Cdd:COG1520 131 AAPAVAGGRVVVRTGDGRVYALDAATGERLWSYQRPVPALTL-------RGTSspvIVGGAVLVGFANGKLVALDLANGQ 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 168 VVWK------------EKVDDyaagysITAAPIIAkGKLITGVSggeFGivGRIDARDPLTGKLVWTRP-------TVEG 228
Cdd:COG1520 204 PLWEqrvaqprgrtelERLVD------VDGTPVVD-GGVVYAVA---YQ--GRLAALDLRSGRVLWSRDlssytglAVDG 271
|
170
....*....|.
gi 1980235597 229 HMGYVVDKDGN 239
Cdd:COG1520 272 NNLYVTDDDGR 282
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
76-222 |
7.42e-14 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 73.43 E-value: 7.42e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 76 AWSMSFG-GEKQRGQESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPdgimpccdvINRGAALYGNLVIFGTL 154
Cdd:TIGR03300 43 VWSASVGdGVGHYYLRLQPAVAGGKVYAADADGTVAALDAETGKRLWRVDLDER---------LSGGVGADGGLVFVGTE 113
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1980235597 155 DAQLVALNKDTGKVVWKEKVddyaaGYSITAAPIIAKGKLItgVSGGEfgivGRIDARDPLTGKLVWT 222
Cdd:TIGR03300 114 KGEVIALDAEDGKELWRAKL-----SSEVLSPPLVANGLVV--VRTND----GRLTALDAATGERLWT 170
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
475-547 |
3.24e-10 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 62.26 E-value: 3.24e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1980235597 475 DYIGVMRAVDPVSGKVVWENKNYAPLWGGAlTTAGGLTFYGTPEGYLKAVDAKTGKELWSFQTGTGIVAPPVT 547
Cdd:TIGR03300 72 DADGTVAALDAETGKRLWRVDLDERLSGGV-GADGGLVFVGTEKGEVIALDAEDGKELWRAKLSSEVLSPPLV 143
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
93-222 |
4.32e-10 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 61.87 E-value: 4.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 93 PVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPDGIMPCcdviNRGAALYG------NLVIFGTLDAQLVALNKDTG 166
Cdd:PRK11138 65 PAVAYNKVYAADRAGLVKALDADTGKEIWSVDLSEKDGWFSK----NKSALLSGgvtvagGKVYIGSEKGQVYALNAEDG 140
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1980235597 167 KVVWKEKVddyaAGYSItAAPIIAKGKLITGVSGgefgivGRIDARDPLTGKLVWT 222
Cdd:PRK11138 141 EVAWQTKV----AGEAL-SRPVVSDGLVLVHTSN------GMLQALNESDGAVKWT 185
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
478-561 |
1.50e-08 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 56.75 E-value: 1.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 478 GVMRAVDPVSGKVVWENKNYAPLWGGaLTTAGGLTFYGTPEGYLKAVDAKTGKELWSFQTGTGIVAPPVTweqdGEQMIA 557
Cdd:COG1520 67 GRVAALDAATGKELWRVDLGEPLSGG-VGADGGLVVVGTEDGEVIALDADDGEELWRARLSSEVLAAPAV----AGGRVV 141
|
....
gi 1980235597 558 VTTG 561
Cdd:COG1520 142 VRTG 145
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
478-561 |
7.09e-08 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 53.56 E-value: 7.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 478 GVMRAVDPVSGKVVWENKNYAPlWGGALTTAGGLTFYGTPEGYLKAVDAKTGKELWSFQTGTGIVAPPvtwEQDGEQMIA 557
Cdd:pfam13360 3 GVVTALDAATGAELWRVDLETG-LGGGVAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLGAP---LVAGGRVFV 78
|
....
gi 1980235597 558 VTTG 561
Cdd:pfam13360 79 VAGD 82
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
478-563 |
9.09e-08 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 54.55 E-value: 9.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 478 GVMRAVDPVSGKVVWEN----------KNYAPLWGGALTTAGGLTFYGTPEGYLKAVDAKTGKELWSFQTGTGIVAPPVT 547
Cdd:PRK11138 79 GLVKALDADTGKEIWSVdlsekdgwfsKNKSALLSGGVTVAGGKVYIGSEKGQVYALNAEDGEVAWQTKVAGEALSRPVV 158
|
90
....*....|....*.
gi 1980235597 548 weqdGEQMIAVTTGWG 563
Cdd:PRK11138 159 ----SDGLVLVHTSNG 170
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
61-245 |
1.57e-07 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 53.78 E-value: 1.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 61 QLAAVN--TGTVknlvpAWSMSFGGEKQrgqeSQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRLPDGIMpccdvi 138
Cdd:PRK11138 131 QVYALNaeDGEV-----AWQTKVAGEAL----SRPVVSDGLVLVHTSNGMLQALNESDGAVKWTVNLDVPSLTL------ 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 139 nRG----AALYGNlVIFGTLDAQLVALNKDTGKVVWKEKVDDYAAGYSIT------AAPIIAKGKLITgvsggeFGIVGR 208
Cdd:PRK11138 196 -RGesapATAFGG-AIVGGDNGRVSAVLMEQGQLIWQQRISQPTGATEIDrlvdvdTTPVVVGGVVYA------LAYNGN 267
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1980235597 209 IDARDPLTGKLVWTRP-------TVEGHMGYVVDKDGN----KKENGI 245
Cdd:PRK11138 268 LVALDLRSGQIVWKREygsvndfAVDGGRIYLVDQNDRvyalDTRGGV 315
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
513-545 |
1.81e-06 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 44.49 E-value: 1.81e-06
10 20 30
....*....|....*....|....*....|...
gi 1980235597 513 FYGTPEGYLKAVDAKTGKELWSFQTGTGIVAPP 545
Cdd:pfam01011 4 YLGSDDGYLYALDAETGKVLWSFKTGGAVLSSP 36
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
90-171 |
9.82e-06 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 47.01 E-value: 9.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 90 ESQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKyehRLPDGIMpccdvinrGAALYGNLVIFGTLDAQLVALNKDTGKVV 169
Cdd:pfam13360 162 TGTPVVAGGRVFASAYQGRLVAFDAATGRRLWT---REISGPN--------GPILDGDLLYVVSDDGELYALDRATGAVV 230
|
..
gi 1980235597 170 WK 171
Cdd:pfam13360 231 WK 232
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
91-238 |
1.36e-05 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 47.62 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 91 SQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYEHRlpdgimpccdvINRGAALYGNLVIFGTLDAQLVALNKDTGKVVW 170
Cdd:TIGR03300 235 GDPVVDGGQVYAVSYQGRVAALDLRSGRVLWKRDAS-----------SYQGPAVDDNRLYVTDADGVVVALDRRSGSELW 303
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1980235597 171 KEkvdDYAAGYSITAaPIIAKGKLITGVSGGEFGIV----GRIDARDPLTGKLVWTRPTVEGHMGYVVDKDG 238
Cdd:TIGR03300 304 KN---DELKYRQLTA-PAVLGGYLVVGDFEGYLHWLdrddGSFVARLKTDGSGIASPPVVVGDGLLVQTRDG 371
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
45-195 |
1.37e-05 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 47.50 E-value: 1.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 45 GDVVsFGLGTQGQrfsqLAAVN--TGTVknlvpAWSMSFGGEKQrgqesqPVIHDGKMFVTASYSRLFAIDAKTGKKLWK 122
Cdd:COG1520 233 GGVV-YAVAYQGR----LAALDlrSGRV-----LWSRDLSSYTG------LAVDGNNLYVTDDDGRVWALDRRNGAELWK 296
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1980235597 123 YEHRLpdgimpccdviNRG---AALYGNLVIFGTLDAQLVALNKDTGKVVWKEKVDDYAagysITAAPIIAKGKLI 195
Cdd:COG1520 297 QDALL-----------YRGltaPVVLGDYVVVGDFEGYLHWLSRDDGSLVARLRVDGSG----IRAAPVVVGDTLY 357
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
44-222 |
1.85e-05 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 46.24 E-value: 1.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 44 PGDVVSFGLGTQGQRF-----SQLAAVNtgtVKNLVPAWSMSFGGEKQR-GQESQPVIHDGKMFVTASYSRLFAIDAKTG 117
Cdd:pfam13360 62 SGEVLGAPLVAGGRVFvvagdGSLIALD---AADGRRLWSYQRSGEPLAlRSSGSPAVVGDTVVAGFSSGKLVALDPATG 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 118 KKLWKYEHRLPDGIMPCCDV--INRGAALYGNLVIFGTLDAQLVALNKDTGKVVWKEKVddyaAGYSitaaPIIAKGKLI 195
Cdd:pfam13360 139 KVRWEAPLAAPRGTNELERLvdITGTPVVAGGRVFASAYQGRLVAFDAATGRRLWTREI----SGPN----GPILDGDLL 210
|
170 180
....*....|....*....|....*..
gi 1980235597 196 TGVSGGefgivGRIDARDPLTGKLVWT 222
Cdd:pfam13360 211 YVVSDD-----GELYALDRATGAVVWK 232
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
430-540 |
2.32e-05 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 45.86 E-value: 2.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 430 AYNPQTGlfyvpANEWGMDI---WNEPVAYKKGAAYLGAGFtikplhedyiGVMRAVDPVSGKVVWENKNYAPLwGGALT 506
Cdd:pfam13360 7 ALDAATG-----AELWRVDLetgLGGGVAVDGGRLFVATGG----------GQLVALDAATGKLLWRQTLSGEV-LGAPL 70
|
90 100 110
....*....|....*....|....*....|....
gi 1980235597 507 TAGGLTFYGTPEGYLKAVDAKTGKELWSFQTGTG 540
Cdd:pfam13360 71 VAGGRVFVVAGDGSLIALDAADGRRLWSYQRSGE 104
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
29-222 |
3.07e-05 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 46.56 E-value: 3.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 29 AKDVTDADILNDAKTPGDVVSFGLGTQG-------QRFSQLAAVNTgtvKNLVPAWSMSFGgekQRGQESQPVIHDGKMF 101
Cdd:cd10276 52 AFNATTGKIIWETSLSGKGFLGGTPAVGngkifvgTESGYLYALDA---KDGSELWRTEVS---DSQLLSPPTYADGKIY 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 102 VTASYSRLFAIDAKTGKKLWKYEHRLPDGIMPC-------CDV---------------------------INRGA----- 142
Cdd:cd10276 126 VGTGDGRLYYCNAETGKVVWNRTSTAPELSLRGgaapvgaYDVvfvgdgngtvvalntgtgvdiwefsvsEPRGRtelpr 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 143 --------ALYGNLVIFGTLDAQLVALNKDTGKVVWKekvDDYAAGYSItaaPIIAKGKLITGVSGGEFGIVgridarDP 214
Cdd:cd10276 206 midssvtyVVVGGYLYSTSYQGYLVALDFESGQFLWS---RKASGGTST---STDANGRVYVGDGEGSLYCL------DA 273
|
....*...
gi 1980235597 215 LTGKLVWT 222
Cdd:cd10276 274 STGDELWS 281
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
45-201 |
8.74e-05 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 44.92 E-value: 8.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 45 GDVVsFGLGTQGQrfsqLAAVNtgtVKNLVPAWSMSFGGEKQrgqesqPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYE 124
Cdd:TIGR03300 241 GGQV-YAVSYQGR----VAALD---LRSGRVLWKRDASSYQG------PAVDDNRLYVTDADGVVVALDRRSGSELWKND 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 125 hrlpdgimpccDVINR---GAALYGNLVIFGTLDAQLVALNKDTGKVVWKEKVDDYAagysITAAPIIAKGKLITGVSGG 201
Cdd:TIGR03300 307 -----------ELKYRqltAPAVLGGYLVVGDFEGYLHWLDRDDGSFVARLKTDGSG----IASPPVVVGDGLLVQTRDG 371
|
|
| PRK11138 |
PRK11138 |
outer membrane biogenesis protein BamB; Provisional |
94-202 |
8.82e-05 |
|
outer membrane biogenesis protein BamB; Provisional
Pssm-ID: 236857 [Multi-domain] Cd Length: 394 Bit Score: 45.31 E-value: 8.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 94 VIHDGKMFVTASYSRLFAIDAKTGKKLWKYEhrlpdgimpccDVINR---GAALYGNLVIFGTLDAQLVALNKDTGKVVW 170
Cdd:PRK11138 291 AVDGGRIYLVDQNDRVYALDTRGGVELWSQS-----------DLLHRlltAPVLYNGYLVVGDSEGYLHWINREDGRFVA 359
|
90 100 110
....*....|....*....|....*....|..
gi 1980235597 171 KEKVDDYAagysITAAPIIAKGKLITGVSGGE 202
Cdd:PRK11138 360 QQKVDSSG----FLSEPVVADDKLLIQARDGT 387
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
475-547 |
1.36e-04 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 44.25 E-value: 1.36e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1980235597 475 DYIGVMRAVDPVSGKVVWENK-NYAPLWGGALTTAGGLTFYGTPEGYLKAVDAKTGKELWSFQTGTGIVAPPVT 547
Cdd:cd10276 45 DANGQVSAFNATTGKIIWETSlSGKGFLGGTPAVGNGKIFVGTESGYLYALDAKDGSELWRTEVSDSQLLSPPT 118
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
383-559 |
3.60e-04 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 43.00 E-value: 3.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 383 KSIDLKTGRPVYD---DENRPGDPTAGDGKkgktvfsapSFLGGKNQQQIAYNPQTGlfyvpanewgMDIWNEPVaykkG 459
Cdd:TIGR03300 78 AALDAETGKRLWRvdlDERLSGGVGADGGL---------VFVGTEKGEVIALDAEDG----------KELWRAKL----S 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 460 AAYLGAgftikPLHEDYIGVMR-------AVDPVSGKVVWENKNYAP---LWG-GALTTAGGLTFYGTPEGYLKAVDAKT 528
Cdd:TIGR03300 135 SEVLSP-----PLVANGLVVVRtndgrltALDAATGERLWTYSRVTPpltLRGsASPVIADGGVLVGFAGGKLVALDLQT 209
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1980235597 529 GKELW--SFQTGTG---------IVAPPVTweqDGEQMIAVT 559
Cdd:TIGR03300 210 GQPLWeqRVALPKGrtelerlvdVDGDPVV---DGGQVYAVS 248
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
304-534 |
3.99e-04 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 42.39 E-value: 3.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 304 VAIDADTGKIVWhyQNTPHDGWD------------FDGVNEFVSFDfkdPKTGKVVkagGKADRNGFFFVNDRTNGKLLN 371
Cdd:pfam13360 6 TALDAATGAELW--RVDLETGLGggvavdggrlfvATGGGQLVALD---AATGKLL---WRQTLSGEVLGAPLVAGGRVF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 372 AFPFVNKITwakSIDLKTGRPVYDDEnRPGDPTAGDGKKGKTVFSAPSFLGGKNQQQIAYNPQTGLFyvpanewgmdIWN 451
Cdd:pfam13360 78 VVAGDGSLI---ALDAADGRRLWSYQ-RSGEPLALRSSGSPAVVGDTVVAGFSSGKLVALDPATGKV----------RWE 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 452 EPVAYKKGAAYLGAGFTIKP---LHEDYI------GVMRAVDPVSGKVVWENKNYAPLwGGALttAGGLTFYGTPEGYLK 522
Cdd:pfam13360 144 APLAAPRGTNELERLVDITGtpvVAGGRVfasayqGRLVAFDAATGRRLWTREISGPN-GPIL--DGDLLYVVSDDGELY 220
|
250
....*....|..
gi 1980235597 523 AVDAKTGKELWS 534
Cdd:pfam13360 221 ALDRATGAVVWK 232
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
349-538 |
1.03e-03 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 41.55 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 349 AGGK---ADRNGFFFVNDRTNGKLLnafpfvnkitWAKSIDLKTgrpvyddeNRPGDPTAGDGKkgktvfsapSFLGGKN 425
Cdd:cd10276 37 AGDMvyaADANGQVSAFNATTGKII----------WETSLSGKG--------FLGGTPAVGNGK---------IFVGTES 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 426 QQQIAYNPQTGlfyvpaNEwgmdIWNE---------PVAYKKGAAYLGAGFTikplhEDYigvmrAVDPVSGKVVWENKN 496
Cdd:cd10276 90 GYLYALDAKDG------SE----LWRTevsdsqllsPPTYADGKIYVGTGDG-----RLY-----YCNAETGKVVWNRTS 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1980235597 497 YAP---LWGGA-LTTAGGLTFYGTPEGYLKAVDAKTGKELWSFQTG 538
Cdd:cd10276 150 TAPelsLRGGAaPVGAYDVVFVGDGNGTVVALNTGTGVDIWEFSVS 195
|
|
| PA2928_fam |
NF041516 |
PA2928 family protein; This family is named for the locus PA2928 of Pseudomonas aeroginosa ... |
105-173 |
1.07e-03 |
|
PA2928 family protein; This family is named for the locus PA2928 of Pseudomonas aeroginosa PAO1, as the family member most frequently cited in the literature, although PA2928 itself is significantly shorter at the N-terminus than most other members of this family, and is probably non-functional. WP_017001489.1 represents an intact equivalent to the PA2928 pseudogene.
Pssm-ID: 469402 [Multi-domain] Cd Length: 345 Bit Score: 41.59 E-value: 1.07e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1980235597 105 SYSRLFAIDAKTGKKLWKyeHRLPDGimpccdvINRGAALYG---NLVIFGTlDAQLVALNKDTGKVVWKEK 173
Cdd:NF041516 67 SQFRLAAVDLATGEKLWD--KKLSDE-------LSWEAYLLGatdRYLYVAT-DKGLYVLDLATGKVVADEK 128
|
|
| PQQ |
smart00564 |
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline ... |
96-123 |
1.09e-03 |
|
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.
Pssm-ID: 128836 [Multi-domain] Cd Length: 33 Bit Score: 36.74 E-value: 1.09e-03
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
478-533 |
1.56e-03 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 40.95 E-value: 1.56e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 478 GVMRAVDPVSGKVVWENKNYAP---LWG-GALTTAGGLTFYGTPEGYLKAVDAKTGKELW 533
Cdd:COG1520 147 GRVYALDAATGERLWSYQRPVPaltLRGtSSPVIVGGAVLVGFANGKLVALDLANGQPLW 206
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
91-201 |
1.85e-03 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 40.78 E-value: 1.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 91 SQPVIHDGKMFVTASYSRLFAIDAKTGKKLWKYehrlpdgimpccDVINRG-----AALYGNLVIFGTLDAQLVALNKDT 165
Cdd:cd10276 250 STSTDANGRVYVGDGEGSLYCLDASTGDELWSQ------------TVLLGRvlsspAIYVGVYIYVTDNAEGYLYCLKDN 317
|
90 100 110
....*....|....*....|....*....|....*.
gi 1980235597 166 GKVVWKEKVDDYAAGysITAAPIIAKGKLITGVSGG 201
Cdd:cd10276 318 DGLTVARVEVDYSQY--ILQGPAVSDGWLYYGTDDG 351
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
155-315 |
2.02e-03 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 40.08 E-value: 2.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 155 DAQLVALNKDTGKVVWKEKVDDyaagySITAAPIIAKGKLITGvsggefGIVGRIDARDPLTGKLVWTR---------PT 225
Cdd:pfam13360 2 DGVVTALDAATGAELWRVDLET-----GLGGGVAVDGGRLFVA------TGGGQLVALDAATGKLLWRQtlsgevlgaPL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 226 VEGHMGYVVDKDGN----KKENG--------------ISGTANATWSGD-------------LWKTGGAATWNGATYDPE 274
Cdd:pfam13360 71 VAGGRVFVVAGDGSlialDAADGrrlwsyqrsgeplaLRSSGSPAVVGDtvvagfssgklvaLDPATGKVRWEAPLAAPR 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1980235597 275 --TNLIFAGTGNPAPwnshLRPGDNLFSSS----TVAIDADTGKIVW 315
Cdd:pfam13360 151 gtNELERLVDITGTP----VVAGGRVFASAyqgrLVAFDAATGRRLW 193
|
|
| Luminal_IRE1_like |
cd09213 |
The Luminal domain, a dimerization domain, of Inositol-requiring protein 1-like proteins; The ... |
97-224 |
3.81e-03 |
|
The Luminal domain, a dimerization domain, of Inositol-requiring protein 1-like proteins; The Luminal domain is a dimerization domain present in Inositol-requiring protein 1 (IRE1), eukaryotic translation Initiation Factor 2-Alpha Kinase 3 (EIF2AK3), and similar proteins. IRE1 and EIF2AK3 are serine/threonine protein kinases (STKs) and are type I transmembrane proteins that are localized in the endoplasmic reticulum (ER). They are kinase receptors that are activated through the release of BiP, a chaperone bound to their luminal domains under unstressed conditions. This results in dimerization through their luminal domains, allowing trans-autophosphorylation of their kinase domains and activation. They play roles in the signaling of the unfolded protein response (UPR), which is activated when protein misfolding is detected in the ER in order to decrease the synthesis of new proteins and increase the capacity of the ER to cope with the stress. IRE1, also called Endoplasmic reticulum (ER)-to-nucleus signaling protein (or ERN), contains an endoribonuclease domain in its cytoplasmic side and acts as an ER stress sensor. It is the oldest and most conserved component of the UPR in eukaryotes. Its activation results in the cleavage of its mRNA substrate, HAC1 in yeast and Xbp1 in metazoans, promoting a splicing event that enables translation into a transcription factor which activates the UPR. EIF2AK3, also called PKR-like Endoplasmic Reticulum Kinase (PERK), phosphorylates the alpha subunit of eIF-2, resulting in the downregulation of protein synthesis. It functions as the central regulator of translational control during the UPR pathway. In addition to the eIF-2 alpha subunit, EIF2AK3 also phosphorylates Nrf2, a leucine zipper transcription factor which regulates cellular redox status and promotes cell survival during the UPR.
Pssm-ID: 188873 [Multi-domain] Cd Length: 312 Bit Score: 39.78 E-value: 3.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 97 DGKMFVTASYSRLFAIDAKTGK--------KLWKYEHRLPDGIMPCCDVINrgaALYGNLVIFGTLDAQLVALNKDTGKV 168
Cdd:cd09213 93 DDVVVVGSKRTSVFALDAKTGKiiktyradGLPSTGGSDSDGNSTPGPDEL---QEEEELLYIGRTDYVLQAIDPRSGKE 169
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90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1980235597 169 VWKEKVDDYAAGYSI--TAAPIIAKGKLITGVSGGEFGIVGRIDARDPLTGKLVWTRP 224
Cdd:cd09213 170 LWNVTYGEYEALTLDadELGTSSSSSPLSASFRISENEPVPAVYLLGLQGGKSLWEHL 227
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| PQQ |
smart00564 |
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline ... |
142-171 |
5.28e-03 |
|
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.
Pssm-ID: 128836 [Multi-domain] Cd Length: 33 Bit Score: 34.82 E-value: 5.28e-03
10 20 30
....*....|....*....|....*....|
gi 1980235597 142 AALYGNLVIFGTLDAQLVALNKDTGKVVWK 171
Cdd:smart00564 2 VVLSDGTVYVGSTDGTLYALDAKTGEILWT 31
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| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
484-543 |
9.41e-03 |
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Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 38.47 E-value: 9.41e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980235597 484 DPVSGKVVWENKNYAPLWGGALTT---AGGLTFYGTPEGYLKAVDAKTGKELWS-------FQTGTGIVA 543
Cdd:cd10276 10 PEFDPEVLWSKSVGNGGMAGIDLTpvvAGDMVYAADANGQVSAFNATTGKIIWEtslsgkgFLGGTPAVG 79
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