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Conserved domains on  [gi|1967466532|gb|QQY96671|]
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VP1 [Equine encephalosis virus 5]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Orbi_VP1 super family cl12314
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 3-1306 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


The actual alignment was detected with superfamily member pfam05788:

Pssm-ID: 461740  Cd Length: 1297  Bit Score: 1039.67  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532    3 ITVDGAEVVREALNRIFKYGAFQGDTPVYEYYRYSSRIRQLRRKHGAKYSISDAEMERRRDRGELSLYGLQVITENEVTQ 82
Cdd:pfam05788    4 ITVQGAQLIKRVVERFYPGIAFAINEGACYIYKFSDHIRRIRMKHGTKYRRQAEEILRKISLRKERLYGIPVLDEVEWKY 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532   83 ILKLPTHDqgVEIVDIFYNSVLPCDELEPDEEFLRNYRVE-ENHGLQTFISYRASQEMQVFGDLPLNFWCAFIESASSYF 161
Cdd:pfam05788   84 VFDGQTFQ--SYAFEVYVNSILPWSELDPEEEFLRNYRVSrEKTEVEKFIEFRAKNEMQIYGDIPIKVWCCFINELSIEL 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  162 EHEPLGLTVLRQITCDKGVLFHQNSRDLSQIEDISYTYSGPLLFEMCITESILEYNMVCRMREEKISDLQYGHDSINPFE 241
Cdd:pfam05788  162 GMQPLGMQVMADFVNRFQSPFHQGNRDLSNLEDFQVAYTTPLLFEMCCMESILEFNIKMRMREEEISALEFGDVKLDPVG 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  242 IIREFFIMCLPHPKKINNMLRSPYSWMVKTWGICCAEQVILDSRGGPDRNSKDVFYTGYRKVVNQYgpillkTRFFKDSL 321
Cdd:pfam05788  242 LLREFFILCLPHPKKINNVLRAPYSWFVKMWGVGADPIVVLQSTAGDDRNSKDVFYDKFRTEPNRY------KALFRSSF 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  322 KLNREKVEEAIKYSQCLGGHRRSLNIFRSMLKKPYTTEFDPSNVRHVMLASLLLSIQTITGYGRAWVKNESSDVESQMKP 401
Cdd:pfam05788  316 YNESRRMNEEKILEAVKYSQDLGSHDRRLPLFEKMLKPVYTTPFYPHKSSNMILASFLLSIQTITGYGRAWVKNVSTEFD 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  402 NDNNLISRVSEYTGRNFYNAYAEAKEAGEEIVKPEDMYTSLLRLAKNTSSGFSTEIVVNKRFGPGISASSFEKI---KIS 478
Cdd:pfam05788  396 KQLKPNPSNLVLDVSDLTREFFKQAYVEAKERREEDVKPEDLYTSMLRLARNTSSGFSTEIYVKKRFGPRLRDKdlrKIN 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  479 SRIKALVIFTKGHEVFTPSNLVQKYDTVEYYQTKGSRDVPIKSTRTIYAINLSILMPQLLLTLPLNEYFAKVGGSTLPDY 558
Cdd:pfam05788  476 SRIKALVIFTKGHTVFTDEELHKKYNSVELYQTKGSRDVPIKATRTIYSINLSVLVPQLIVTLPLNEYFSRVGGITKPDY 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  559 KRLGGKVIVGDLEATGSRTMDAADCFRNSSDPMILTIAIDYSDYDQHLTPYNFRSGMLKGIRDWVKHYEHYNYDGQTVYD 638
Cdd:pfam05788  556 KKIGGKVIVGDLEATGSRVMDAADCFRNSADRDIFTIAIDYSEYDTHLTRHNFRTGMLQGIREAMAPYRGLRYEGYTLEQ 635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  639 LIEYGYGEGRVQNSFWKGKSAVKKVDLDEYMDLNDDERFVGSFRPPRGSLPVRDRAVYDRLKCTPGKEhVVISPTDGSDL 718
Cdd:pfam05788  636 IIDFGYGEGRVANTLWNGKRRLFKTTFDAYIRLDESERDKGSFKVPKGVLPVSSVDVANRIAVDKGFD-TLIAATDGSDL 714

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  719 ARVNTHLSGENSTLVANSLHNMAIGRIMQEEIHKYCYGKIEFLSEQYVGDDTLFYTKPHCRSPEDFDAIFDVIFNTIKKC 798
Cdd:pfam05788  715 ALIDTHLSGENSTLIANSMHNMAIGTLGQRQVGREQPGSLTFLSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAKC 794

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  799 GHEASPSKTLIAPFSVEKTQTHAKAGIYVGQDRMMIVSSERKKDIEDVGGYLASQIQTLTTKVSRGFSHELAQLVFMMKS 878
Cdd:pfam05788  795 GHEASPSKTMMTPYSVEKTQTHAKQGCYVPQDRMMIISSERRKDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLKT 874

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  879 TVIGFRKLKRTIKDTHGYRDRSFDHQEEDGFTLMMIKDPLVAFLPREWGGAGMNPLAINVVNTEEVFLDMAADPFFREIM 958
Cdd:pfam05788  875 TFIGAWKMKRTIKEDAMYRDRKFDSNDEDGFTLIQIRNPLALYVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEIM 954

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  959 DPLLKILQPMPPVWNETRGDKRSLSSDTAMGFFSKMARPMVRLAFDNPIVGDLVKNLPLGDYSPFNLSHTMMRSALLKEQ 1038
Cdd:pfam05788  955 APIRRIVHDIPPCWNETQGDKRGLISATKKSFFSKMARPAVQAALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKES 1034

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532 1039 RARALLAPGYELEYQRELskkwkEPSFTLGSKKdMEIDSGYAKIFDVVPFGREVVESHFFPDVNISPEFYIQKVKLGHRN 1118
Cdd:pfam05788 1035 SASGLLSSGYKLEYQKAL-----NVWIRQVSMR-LGEESGVISTSYAKLFDVYFEGELDGAPQMFPDQNLSPQFYIQKMM 1108

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532 1119 ASRQRMSYIDRIDGILRGDVVMRGFLTSGTIMSILDDIGPVHDASDLS-----MLFQMLNLSSIVADRLATYISSERVKF 1193
Cdd:pfam05788 1109 IGPRVSSRVRNSYVDRIDVILRKDVVMRGFITANTILNVIEKLGTNHSvgdlvTVFTLMNIETRVAEELAEYMTSEKIRF 1188

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532 1194 DSLQIAKRGIGGDEFTMSLNVLTGEFMDRYLRVPPQFTKTEVDACLLYVAQLCMINCFKEGSLKRLDINVSNNERRRIRQ 1273
Cdd:pfam05788 1189 DALKLLKKGIAGDEFTMSLNVATQDFIDTYLAYPYQLTKTEVDAISLYCTQMAMLRAALGLPKKKMKIVVTDDAKKRYKI 1268

                         1290      1300      1310
                   ....*....|....*....|....*....|...
gi 1967466532 1274 RIARYRTFVPPMRILRRaarseRIAARMVGNQF 1306
Cdd:pfam05788 1269 RLQRFRTHVPKIKVLKK-----LIDPNRMTVRN 1296
 
Name Accession Description Interval E-value
Orbi_VP1 pfam05788
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 3-1306 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


Pssm-ID: 461740  Cd Length: 1297  Bit Score: 1039.67  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532    3 ITVDGAEVVREALNRIFKYGAFQGDTPVYEYYRYSSRIRQLRRKHGAKYSISDAEMERRRDRGELSLYGLQVITENEVTQ 82
Cdd:pfam05788    4 ITVQGAQLIKRVVERFYPGIAFAINEGACYIYKFSDHIRRIRMKHGTKYRRQAEEILRKISLRKERLYGIPVLDEVEWKY 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532   83 ILKLPTHDqgVEIVDIFYNSVLPCDELEPDEEFLRNYRVE-ENHGLQTFISYRASQEMQVFGDLPLNFWCAFIESASSYF 161
Cdd:pfam05788   84 VFDGQTFQ--SYAFEVYVNSILPWSELDPEEEFLRNYRVSrEKTEVEKFIEFRAKNEMQIYGDIPIKVWCCFINELSIEL 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  162 EHEPLGLTVLRQITCDKGVLFHQNSRDLSQIEDISYTYSGPLLFEMCITESILEYNMVCRMREEKISDLQYGHDSINPFE 241
Cdd:pfam05788  162 GMQPLGMQVMADFVNRFQSPFHQGNRDLSNLEDFQVAYTTPLLFEMCCMESILEFNIKMRMREEEISALEFGDVKLDPVG 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  242 IIREFFIMCLPHPKKINNMLRSPYSWMVKTWGICCAEQVILDSRGGPDRNSKDVFYTGYRKVVNQYgpillkTRFFKDSL 321
Cdd:pfam05788  242 LLREFFILCLPHPKKINNVLRAPYSWFVKMWGVGADPIVVLQSTAGDDRNSKDVFYDKFRTEPNRY------KALFRSSF 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  322 KLNREKVEEAIKYSQCLGGHRRSLNIFRSMLKKPYTTEFDPSNVRHVMLASLLLSIQTITGYGRAWVKNESSDVESQMKP 401
Cdd:pfam05788  316 YNESRRMNEEKILEAVKYSQDLGSHDRRLPLFEKMLKPVYTTPFYPHKSSNMILASFLLSIQTITGYGRAWVKNVSTEFD 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  402 NDNNLISRVSEYTGRNFYNAYAEAKEAGEEIVKPEDMYTSLLRLAKNTSSGFSTEIVVNKRFGPGISASSFEKI---KIS 478
Cdd:pfam05788  396 KQLKPNPSNLVLDVSDLTREFFKQAYVEAKERREEDVKPEDLYTSMLRLARNTSSGFSTEIYVKKRFGPRLRDKdlrKIN 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  479 SRIKALVIFTKGHEVFTPSNLVQKYDTVEYYQTKGSRDVPIKSTRTIYAINLSILMPQLLLTLPLNEYFAKVGGSTLPDY 558
Cdd:pfam05788  476 SRIKALVIFTKGHTVFTDEELHKKYNSVELYQTKGSRDVPIKATRTIYSINLSVLVPQLIVTLPLNEYFSRVGGITKPDY 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  559 KRLGGKVIVGDLEATGSRTMDAADCFRNSSDPMILTIAIDYSDYDQHLTPYNFRSGMLKGIRDWVKHYEHYNYDGQTVYD 638
Cdd:pfam05788  556 KKIGGKVIVGDLEATGSRVMDAADCFRNSADRDIFTIAIDYSEYDTHLTRHNFRTGMLQGIREAMAPYRGLRYEGYTLEQ 635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  639 LIEYGYGEGRVQNSFWKGKSAVKKVDLDEYMDLNDDERFVGSFRPPRGSLPVRDRAVYDRLKCTPGKEhVVISPTDGSDL 718
Cdd:pfam05788  636 IIDFGYGEGRVANTLWNGKRRLFKTTFDAYIRLDESERDKGSFKVPKGVLPVSSVDVANRIAVDKGFD-TLIAATDGSDL 714

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  719 ARVNTHLSGENSTLVANSLHNMAIGRIMQEEIHKYCYGKIEFLSEQYVGDDTLFYTKPHCRSPEDFDAIFDVIFNTIKKC 798
Cdd:pfam05788  715 ALIDTHLSGENSTLIANSMHNMAIGTLGQRQVGREQPGSLTFLSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAKC 794

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  799 GHEASPSKTLIAPFSVEKTQTHAKAGIYVGQDRMMIVSSERKKDIEDVGGYLASQIQTLTTKVSRGFSHELAQLVFMMKS 878
Cdd:pfam05788  795 GHEASPSKTMMTPYSVEKTQTHAKQGCYVPQDRMMIISSERRKDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLKT 874

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  879 TVIGFRKLKRTIKDTHGYRDRSFDHQEEDGFTLMMIKDPLVAFLPREWGGAGMNPLAINVVNTEEVFLDMAADPFFREIM 958
Cdd:pfam05788  875 TFIGAWKMKRTIKEDAMYRDRKFDSNDEDGFTLIQIRNPLALYVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEIM 954

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  959 DPLLKILQPMPPVWNETRGDKRSLSSDTAMGFFSKMARPMVRLAFDNPIVGDLVKNLPLGDYSPFNLSHTMMRSALLKEQ 1038
Cdd:pfam05788  955 APIRRIVHDIPPCWNETQGDKRGLISATKKSFFSKMARPAVQAALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKES 1034

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532 1039 RARALLAPGYELEYQRELskkwkEPSFTLGSKKdMEIDSGYAKIFDVVPFGREVVESHFFPDVNISPEFYIQKVKLGHRN 1118
Cdd:pfam05788 1035 SASGLLSSGYKLEYQKAL-----NVWIRQVSMR-LGEESGVISTSYAKLFDVYFEGELDGAPQMFPDQNLSPQFYIQKMM 1108

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532 1119 ASRQRMSYIDRIDGILRGDVVMRGFLTSGTIMSILDDIGPVHDASDLS-----MLFQMLNLSSIVADRLATYISSERVKF 1193
Cdd:pfam05788 1109 IGPRVSSRVRNSYVDRIDVILRKDVVMRGFITANTILNVIEKLGTNHSvgdlvTVFTLMNIETRVAEELAEYMTSEKIRF 1188

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532 1194 DSLQIAKRGIGGDEFTMSLNVLTGEFMDRYLRVPPQFTKTEVDACLLYVAQLCMINCFKEGSLKRLDINVSNNERRRIRQ 1273
Cdd:pfam05788 1189 DALKLLKKGIAGDEFTMSLNVATQDFIDTYLAYPYQLTKTEVDAISLYCTQMAMLRAALGLPKKKMKIVVTDDAKKRYKI 1268

                         1290      1300      1310
                   ....*....|....*....|....*....|...
gi 1967466532 1274 RIARYRTFVPPMRILRRaarseRIAARMVGNQF 1306
Cdd:pfam05788 1269 RLQRFRTHVPKIKVLKK-----LIDPNRMTVRN 1296
 
Name Accession Description Interval E-value
Orbi_VP1 pfam05788
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 3-1306 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


Pssm-ID: 461740  Cd Length: 1297  Bit Score: 1039.67  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532    3 ITVDGAEVVREALNRIFKYGAFQGDTPVYEYYRYSSRIRQLRRKHGAKYSISDAEMERRRDRGELSLYGLQVITENEVTQ 82
Cdd:pfam05788    4 ITVQGAQLIKRVVERFYPGIAFAINEGACYIYKFSDHIRRIRMKHGTKYRRQAEEILRKISLRKERLYGIPVLDEVEWKY 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532   83 ILKLPTHDqgVEIVDIFYNSVLPCDELEPDEEFLRNYRVE-ENHGLQTFISYRASQEMQVFGDLPLNFWCAFIESASSYF 161
Cdd:pfam05788   84 VFDGQTFQ--SYAFEVYVNSILPWSELDPEEEFLRNYRVSrEKTEVEKFIEFRAKNEMQIYGDIPIKVWCCFINELSIEL 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  162 EHEPLGLTVLRQITCDKGVLFHQNSRDLSQIEDISYTYSGPLLFEMCITESILEYNMVCRMREEKISDLQYGHDSINPFE 241
Cdd:pfam05788  162 GMQPLGMQVMADFVNRFQSPFHQGNRDLSNLEDFQVAYTTPLLFEMCCMESILEFNIKMRMREEEISALEFGDVKLDPVG 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  242 IIREFFIMCLPHPKKINNMLRSPYSWMVKTWGICCAEQVILDSRGGPDRNSKDVFYTGYRKVVNQYgpillkTRFFKDSL 321
Cdd:pfam05788  242 LLREFFILCLPHPKKINNVLRAPYSWFVKMWGVGADPIVVLQSTAGDDRNSKDVFYDKFRTEPNRY------KALFRSSF 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  322 KLNREKVEEAIKYSQCLGGHRRSLNIFRSMLKKPYTTEFDPSNVRHVMLASLLLSIQTITGYGRAWVKNESSDVESQMKP 401
Cdd:pfam05788  316 YNESRRMNEEKILEAVKYSQDLGSHDRRLPLFEKMLKPVYTTPFYPHKSSNMILASFLLSIQTITGYGRAWVKNVSTEFD 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  402 NDNNLISRVSEYTGRNFYNAYAEAKEAGEEIVKPEDMYTSLLRLAKNTSSGFSTEIVVNKRFGPGISASSFEKI---KIS 478
Cdd:pfam05788  396 KQLKPNPSNLVLDVSDLTREFFKQAYVEAKERREEDVKPEDLYTSMLRLARNTSSGFSTEIYVKKRFGPRLRDKdlrKIN 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  479 SRIKALVIFTKGHEVFTPSNLVQKYDTVEYYQTKGSRDVPIKSTRTIYAINLSILMPQLLLTLPLNEYFAKVGGSTLPDY 558
Cdd:pfam05788  476 SRIKALVIFTKGHTVFTDEELHKKYNSVELYQTKGSRDVPIKATRTIYSINLSVLVPQLIVTLPLNEYFSRVGGITKPDY 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  559 KRLGGKVIVGDLEATGSRTMDAADCFRNSSDPMILTIAIDYSDYDQHLTPYNFRSGMLKGIRDWVKHYEHYNYDGQTVYD 638
Cdd:pfam05788  556 KKIGGKVIVGDLEATGSRVMDAADCFRNSADRDIFTIAIDYSEYDTHLTRHNFRTGMLQGIREAMAPYRGLRYEGYTLEQ 635

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  639 LIEYGYGEGRVQNSFWKGKSAVKKVDLDEYMDLNDDERFVGSFRPPRGSLPVRDRAVYDRLKCTPGKEhVVISPTDGSDL 718
Cdd:pfam05788  636 IIDFGYGEGRVANTLWNGKRRLFKTTFDAYIRLDESERDKGSFKVPKGVLPVSSVDVANRIAVDKGFD-TLIAATDGSDL 714

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  719 ARVNTHLSGENSTLVANSLHNMAIGRIMQEEIHKYCYGKIEFLSEQYVGDDTLFYTKPHCRSPEDFDAIFDVIFNTIKKC 798
Cdd:pfam05788  715 ALIDTHLSGENSTLIANSMHNMAIGTLGQRQVGREQPGSLTFLSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAKC 794

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  799 GHEASPSKTLIAPFSVEKTQTHAKAGIYVGQDRMMIVSSERKKDIEDVGGYLASQIQTLTTKVSRGFSHELAQLVFMMKS 878
Cdd:pfam05788  795 GHEASPSKTMMTPYSVEKTQTHAKQGCYVPQDRMMIISSERRKDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLKT 874

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  879 TVIGFRKLKRTIKDTHGYRDRSFDHQEEDGFTLMMIKDPLVAFLPREWGGAGMNPLAINVVNTEEVFLDMAADPFFREIM 958
Cdd:pfam05788  875 TFIGAWKMKRTIKEDAMYRDRKFDSNDEDGFTLIQIRNPLALYVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEIM 954

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532  959 DPLLKILQPMPPVWNETRGDKRSLSSDTAMGFFSKMARPMVRLAFDNPIVGDLVKNLPLGDYSPFNLSHTMMRSALLKEQ 1038
Cdd:pfam05788  955 APIRRIVHDIPPCWNETQGDKRGLISATKKSFFSKMARPAVQAALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKES 1034

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532 1039 RARALLAPGYELEYQRELskkwkEPSFTLGSKKdMEIDSGYAKIFDVVPFGREVVESHFFPDVNISPEFYIQKVKLGHRN 1118
Cdd:pfam05788 1035 SASGLLSSGYKLEYQKAL-----NVWIRQVSMR-LGEESGVISTSYAKLFDVYFEGELDGAPQMFPDQNLSPQFYIQKMM 1108

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532 1119 ASRQRMSYIDRIDGILRGDVVMRGFLTSGTIMSILDDIGPVHDASDLS-----MLFQMLNLSSIVADRLATYISSERVKF 1193
Cdd:pfam05788 1109 IGPRVSSRVRNSYVDRIDVILRKDVVMRGFITANTILNVIEKLGTNHSvgdlvTVFTLMNIETRVAEELAEYMTSEKIRF 1188

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1967466532 1194 DSLQIAKRGIGGDEFTMSLNVLTGEFMDRYLRVPPQFTKTEVDACLLYVAQLCMINCFKEGSLKRLDINVSNNERRRIRQ 1273
Cdd:pfam05788 1189 DALKLLKKGIAGDEFTMSLNVATQDFIDTYLAYPYQLTKTEVDAISLYCTQMAMLRAALGLPKKKMKIVVTDDAKKRYKI 1268

                         1290      1300      1310
                   ....*....|....*....|....*....|...
gi 1967466532 1274 RIARYRTFVPPMRILRRaarseRIAARMVGNQF 1306
Cdd:pfam05788 1269 RLQRFRTHVPKIKVLKK-----LIDPNRMTVRN 1296
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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