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Conserved domains on  [gi|1959487600|gb|QQX09805|]
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proteasome 26S subunit, partial [Chersobius signatus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00361 super family cl33178
26 proteosome regulatory subunit 4-like protein; Provisional
 1-28 2.63e-12

26 proteosome regulatory subunit 4-like protein; Provisional


The actual alignment was detected with superfamily member PTZ00361:

Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 57.47  E-value: 2.63e-12
                          10        20
                  ....*....|....*....|....*...
gi 1959487600   1 VTVMKVEKAPQETYADIGGLDNQIQEIK 28
Cdd:PTZ00361  169 VSVMKVDKAPLESYADIGGLEQQIQEIK 196
 
Name Accession Description Interval E-value
PTZ00361 PTZ00361
26 proteosome regulatory subunit 4-like protein; Provisional
 1-28 2.63e-12

26 proteosome regulatory subunit 4-like protein; Provisional


Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 57.47  E-value: 2.63e-12
                          10        20
                  ....*....|....*....|....*...
gi 1959487600   1 VTVMKVEKAPQETYADIGGLDNQIQEIK 28
Cdd:PTZ00361  169 VSVMKVDKAPLESYADIGGLEQQIQEIK 196
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 1-28 1.49e-04

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 35.37  E-value: 1.49e-04
                          10        20
                  ....*....|....*....|....*...
gi 1959487600   1 VTVMKVEKAPQETYADIGGLDNQIQEIK 28
Cdd:COG1222    64 RGTAVPAESPDVTFDDIGGLDEQIEEIR 91
RecA-like_PAN_like cd19502
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ...
 13-28 2.37e-04

proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410910 [Multi-domain]  Cd Length: 171  Bit Score: 34.62  E-value: 2.37e-04
                          10
                  ....*....|....*.
gi 1959487600  13 TYADIGGLDNQIQEIK 28
Cdd:cd19502     1 TYEDIGGLDEQIREIR 16
 
Name Accession Description Interval E-value
PTZ00361 PTZ00361
26 proteosome regulatory subunit 4-like protein; Provisional
 1-28 2.63e-12

26 proteosome regulatory subunit 4-like protein; Provisional


Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 57.47  E-value: 2.63e-12
                          10        20
                  ....*....|....*....|....*...
gi 1959487600   1 VTVMKVEKAPQETYADIGGLDNQIQEIK 28
Cdd:PTZ00361  169 VSVMKVDKAPLESYADIGGLEQQIQEIK 196
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
 1-28 1.17e-08

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 46.75  E-value: 1.17e-08
                          10        20
                  ....*....|....*....|....*...
gi 1959487600   1 VTVMKVEKAPQETYADIGGLDNQIQEIK 28
Cdd:PRK03992  117 VQAMEVIESPNVTYEDIGGLEEQIREVR 144
PTZ00454 PTZ00454
26S protease regulatory subunit 6B-like protein; Provisional
 1-28 2.14e-05

26S protease regulatory subunit 6B-like protein; Provisional


Pssm-ID: 240423 [Multi-domain]  Cd Length: 398  Bit Score: 37.82  E-value: 2.14e-05
                          10        20
                  ....*....|....*....|....*...
gi 1959487600   1 VTVMKVEKAPQETYADIGGLDNQIQEIK 28
Cdd:PTZ00454  131 IQLLQMSEKPDVTYSDIGGLDIQKQEIR 158
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 1-28 1.49e-04

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 35.37  E-value: 1.49e-04
                          10        20
                  ....*....|....*....|....*...
gi 1959487600   1 VTVMKVEKAPQETYADIGGLDNQIQEIK 28
Cdd:COG1222    64 RGTAVPAESPDVTFDDIGGLDEQIEEIR 91
RecA-like_PAN_like cd19502
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ...
 13-28 2.37e-04

proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410910 [Multi-domain]  Cd Length: 171  Bit Score: 34.62  E-value: 2.37e-04
                          10
                  ....*....|....*.
gi 1959487600  13 TYADIGGLDNQIQEIK 28
Cdd:cd19502     1 TYEDIGGLDEQIREIR 16
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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