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Conserved domains on  [gi|1955850047|ref|XP_038883086|]
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uncharacterized protein LOC120074142 [Benincasa hispida]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 112-220 3.56e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 3.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955850047  112 RELRLRRKGME----AIKKQSRAMEDGKVSKSEEIKALEEERNTLQTKLKQLELELDSKTKDVTTSEANVVALRKQSEGL 187
Cdd:TIGR02168  820 ANLRERLESLErriaATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL 899

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1955850047  188 LLEYDRLLEENQNLRGQLQSVDHRLSRSGSKKN 220
Cdd:TIGR02168  900 SEELRELESKRSELRRELEELREKLAQLELRLE 932
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 112-220 3.56e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 3.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955850047  112 RELRLRRKGME----AIKKQSRAMEDGKVSKSEEIKALEEERNTLQTKLKQLELELDSKTKDVTTSEANVVALRKQSEGL 187
Cdd:TIGR02168  820 ANLRERLESLErriaATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL 899

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1955850047  188 LLEYDRLLEENQNLRGQLQSVDHRLSRSGSKKN 220
Cdd:TIGR02168  900 SEELRELESKRSELRRELEELREKLAQLELRLE 932
Bap31_Bap29_C pfam18035
Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the ...
 162-204 1.85e-04

Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This entry represents the cytoplasmic domain which forms a heterodimeric coiled-coil with Bap29. This Bap29 and Bap31 are homologous to each other and this entry includes both proteins.


Pssm-ID: 465623 [Multi-domain]  Cd Length: 52  Bit Score: 38.03  E-value: 1.85e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1955850047 162 ELDSKTKDVTTSEANVVALRKQSEGLLLEYDRLLEENQNLRGQ 204
Cdd:pfam18035   2 EIEKLKKELKKKKSDIEALKKQAEGLQREYDRLSDEHAKLQLD 44
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 112-195 1.29e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.98  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955850047 112 RELRLRRKGMEAIKKQSRAMEDGKVSKSEEIKALEEERNTLQTKLKQLELELDSKTKDVTTSEANVVALRKQSEGLLLEY 191
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106


                  ....
gi 1955850047 192 DRLL 195
Cdd:COG4942   107 AELL 110
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 103-164 3.02e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 37.98  E-value: 3.02e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1955850047 103 MIDRLHHYMRELRLRRKGMEAIKKQS----RAMEDGKVSK-SEEIKALEEERNTLQTKLKQLELELD 164
Cdd:PRK05771   58 ALDKLRSYLPKLNPLREEKKKVSVKSleelIKDVEEELEKiEKEIKELEEEISELENEIKELEQEIE 124
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 112-220 3.56e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 3.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955850047  112 RELRLRRKGME----AIKKQSRAMEDGKVSKSEEIKALEEERNTLQTKLKQLELELDSKTKDVTTSEANVVALRKQSEGL 187
Cdd:TIGR02168  820 ANLRERLESLErriaATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL 899

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1955850047  188 LLEYDRLLEENQNLRGQLQSVDHRLSRSGSKKN 220
Cdd:TIGR02168  900 SEELRELESKRSELRRELEELREKLAQLELRLE 932
Bap31_Bap29_C pfam18035
Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the ...
 162-204 1.85e-04

Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This entry represents the cytoplasmic domain which forms a heterodimeric coiled-coil with Bap29. This Bap29 and Bap31 are homologous to each other and this entry includes both proteins.


Pssm-ID: 465623 [Multi-domain]  Cd Length: 52  Bit Score: 38.03  E-value: 1.85e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1955850047 162 ELDSKTKDVTTSEANVVALRKQSEGLLLEYDRLLEENQNLRGQ 204
Cdd:pfam18035   2 EIEKLKKELKKKKSDIEALKKQAEGLQREYDRLSDEHAKLQLD 44
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 112-195 1.29e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.98  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955850047 112 RELRLRRKGMEAIKKQSRAMEDGKVSKSEEIKALEEERNTLQTKLKQLELELDSKTKDVTTSEANVVALRKQSEGLLLEY 191
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106


                  ....
gi 1955850047 192 DRLL 195
Cdd:COG4942   107 AELL 110
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 106-221 1.77e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.59  E-value: 1.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1955850047 106 RLHHYMREL-RLRRKGMEAIKKQSRAMEDGKVSKSEEIKALEEERNTLQTKLKQLELELDSKTKDVTTSEANVVALRKQS 184
Cdd:COG4942   136 RRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAEL 215

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1955850047 185 EGLLLEYDRLLEENQNLRGQLQSVDHRLSRSGSKKNS 221
Cdd:COG4942   216 AELQQEAEELEALIARLEAEAAAAAERTPAAGFAALK 252
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 103-164 3.02e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 37.98  E-value: 3.02e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1955850047 103 MIDRLHHYMRELRLRRKGMEAIKKQS----RAMEDGKVSK-SEEIKALEEERNTLQTKLKQLELELD 164
Cdd:PRK05771   58 ALDKLRSYLPKLNPLREEKKKVSVKSleelIKDVEEELEKiEKEIKELEEEISELENEIKELEQEIE 124
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 113-183 3.62e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 37.89  E-value: 3.62e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1955850047 113 ELRLRRKGMEAIKKQSRAMEDGKVSKSEEIKALEEERNTLQTKLKQLELELDSKTKDVTTSEANVVALRKQ 183
Cdd:COG3883    17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREE 87
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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