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Conserved domains on  [gi|1949155666|ref|WP_198476496|]
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glucose-6-phosphate dehydrogenase [Aquamicrobium zhengzhouense]

Protein Classification

glucose-6-phosphate dehydrogenase (NADP(+))( domain architecture ID 11417513)

glucose-6-phosphate dehydrogenase (NADP(+)) catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Zwf COG0364
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ...
 3-488 0e+00

Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


:

Pssm-ID: 440133 [Multi-domain]  Cd Length: 495  Bit Score: 872.86  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666   3 SQIIPVDPFDFVIFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFVKKEeIDNDQLE 82
Cdd:COG0364     2 TQMRPAEPCDLVIFGATGDLARRKLLPALYNLYRDGLLPEGFRIIGVARRDWSDEEFREEVREALEEFSRKP-FDEEVWE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  83 LFLARLSYRQVNAMSGEGFEGLKEALSE-----SKAVRVFYLAVAPNLFGDIAKNLAAHDLNK--GDVRIVVEKPIGRDQ 155
Cdd:COG0364    81 RFLERLHYVSGDFTDPEGYERLKELLEEldeerTPGNRVFYLATPPSLFGPICENLGAAGLATegGWRRVVIEKPFGHDL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 156 ASARQLNDAIGEVFDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALR 235
Cdd:COG0364   161 ASARELNDELGRVFDESQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVGVEGRGGYYDGAGALR 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 236 DMVQNHMLQLLCLTAMEPPSSMEADAVRDEKLKILRSLRRITDSDASKLTVRGQYRAGASPSGAVRGYAEELG--DRSDT 313
Cdd:COG0364   241 DMVQNHLLQLLCLVAMEPPASLDADAIRDEKVKVLRALRPITPEDVAENTVRGQYTAGWIGGEPVPGYREEPGvaPDSTT 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 314 ETFVAIKAEVANWRWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDESAGPMTANQLVIRLQPDEGVKQWIMIKDPGP 393
Cdd:COG0364   321 ETFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKPVPHSLFRETAEELPPNRLVIRIQPDEGISLRFNAKVPGL 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 394 gGMRLRHIPLDMTFADAFEVRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWANNQQSAQGYTAGTWGPSS 473
Cdd:COG0364   401 -GMRLRPVSLDFSYSDAFGERSPEAYERLLLDVMRGDQTLFMRRDEVEAAWRWVDPILEAWAEEPEPPPPYPAGSWGPEA 479

                         490
                  ....*....|....*
gi 1949155666 474 SIALIERDGRTWHES 488
Cdd:COG0364   480 ADALLARDGRSWREP 494
 
Name Accession Description Interval E-value
Zwf COG0364
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ...
 3-488 0e+00

Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440133 [Multi-domain]  Cd Length: 495  Bit Score: 872.86  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666   3 SQIIPVDPFDFVIFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFVKKEeIDNDQLE 82
Cdd:COG0364     2 TQMRPAEPCDLVIFGATGDLARRKLLPALYNLYRDGLLPEGFRIIGVARRDWSDEEFREEVREALEEFSRKP-FDEEVWE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  83 LFLARLSYRQVNAMSGEGFEGLKEALSE-----SKAVRVFYLAVAPNLFGDIAKNLAAHDLNK--GDVRIVVEKPIGRDQ 155
Cdd:COG0364    81 RFLERLHYVSGDFTDPEGYERLKELLEEldeerTPGNRVFYLATPPSLFGPICENLGAAGLATegGWRRVVIEKPFGHDL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 156 ASARQLNDAIGEVFDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALR 235
Cdd:COG0364   161 ASARELNDELGRVFDESQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVGVEGRGGYYDGAGALR 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 236 DMVQNHMLQLLCLTAMEPPSSMEADAVRDEKLKILRSLRRITDSDASKLTVRGQYRAGASPSGAVRGYAEELG--DRSDT 313
Cdd:COG0364   241 DMVQNHLLQLLCLVAMEPPASLDADAIRDEKVKVLRALRPITPEDVAENTVRGQYTAGWIGGEPVPGYREEPGvaPDSTT 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 314 ETFVAIKAEVANWRWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDESAGPMTANQLVIRLQPDEGVKQWIMIKDPGP 393
Cdd:COG0364   321 ETFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKPVPHSLFRETAEELPPNRLVIRIQPDEGISLRFNAKVPGL 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 394 gGMRLRHIPLDMTFADAFEVRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWANNQQSAQGYTAGTWGPSS 473
Cdd:COG0364   401 -GMRLRPVSLDFSYSDAFGERSPEAYERLLLDVMRGDQTLFMRRDEVEAAWRWVDPILEAWAEEPEPPPPYPAGSWGPEA 479

                         490
                  ....*....|....*
gi 1949155666 474 SIALIERDGRTWHES 488
Cdd:COG0364   480 ADALLARDGRSWREP 494
PRK05722 PRK05722
glucose-6-phosphate 1-dehydrogenase; Validated
 3-487 0e+00

glucose-6-phosphate 1-dehydrogenase; Validated


Pssm-ID: 235579 [Multi-domain]  Cd Length: 495  Bit Score: 835.17  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666   3 SQIIPVDPFDFVIFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFVKkEEIDNDQLE 82
Cdd:PRK05722    2 RLPRTAEPCDLVIFGATGDLARRKLLPALYNLYKAGLLPEDFRIIGVARRDWSDEDFREVVREALKEFAR-TPFDEEVWE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  83 LFLARLSYRQVNAMSGEGFEGLKEALSE------SKAVRVFYLAVAPNLFGDIAKNLAAHDLNK--GDVRIVVEKPIGRD 154
Cdd:PRK05722   81 RFLSRLYYVSGDVTDPESYERLKELLEEldeergTGGNRVFYLATPPSLFGTICENLAAAGLNEggGWRRVVIEKPFGHD 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 155 QASARQLNDAIGEVFDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGAL 234
Cdd:PRK05722  161 LASARELNDQVGEVFKEEQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVGVEGRGGYYDKSGAL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 235 RDMVQNHMLQLLCLTAMEPPSSMEADAVRDEKLKILRSLRRITDSDASKLTVRGQYRAGASPSGAVRGYAEELG--DRSD 312
Cdd:PRK05722  241 RDMVQNHLLQLLALVAMEPPASLDADSIRDEKVKVLRALRPITPEDVKENTVRGQYTAGWIGGKPVPGYREEEGvnPDST 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 313 TETFVAIKAEVANWRWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDESAGPMTANQLVIRLQPDEGVKQWIMIKDPG 392
Cdd:PRK05722  321 TETFVALKLEIDNWRWAGVPFYLRTGKRLPKKVTEIVIVFKPPPHNLFEESAEELGPNKLVIRIQPDEGISLRFNAKVPG 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 393 PgGMRLRHIPLDMTFADAFEVRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWANNQQSAQGYTAGTWGPS 472
Cdd:PRK05722  401 E-GMELRPVKLDFSYSEAFGEASPEAYERLLLDVMLGDQTLFVRRDEVEAAWKWVDPILEAWEADGGPPPPYPAGTWGPE 479

                         490
                  ....*....|....*
gi 1949155666 473 SSIALIERDGRTWHE 487
Cdd:PRK05722  480 AADALLARDGRSWRE 494
zwf TIGR00871
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ...
 9-487 0e+00

glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273312 [Multi-domain]  Cd Length: 487  Bit Score: 615.48  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666   9 DPFDFVIFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFVKKEeiDNDQLELFLARL 88
Cdd:TIGR00871   1 DPCILVIFGASGDLARKKLFPALYRLFRNGLLPPDFRIVGVARRDWSVEEFRKVVREAIIKFETDE--IDEQWDEFAQRL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  89 SYRQVNAMSGEGFEGLKEALSES------KAVRVFYLAVAPNLFGDIAKNLAAHDLNK-GDV-RIVVEKPIGRDQASARQ 160
Cdd:TIGR00871  79 SYVSGDVDDDESYDSLAELLEQLdktygtEGNRLFYLATPPSLFGTIIKQLKKHGLNEqGKWsRVVVEKPFGHDLASAQE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 161 LNDAIGEVFDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALRDMVQN 240
Cdd:TIGR00871 159 LNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQIFEPLWNRRYIDHVQITVAESFGVEGRGGYYDKSGALRDMVQN 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 241 HMLQLLCLTAMEPPSSMEADAVRDEKLKILRSLRRITDSDASklTVRGQYRAGASPSGAVRGYAEELG--DRSDTETFVA 318
Cdd:TIGR00871 239 HLLQLLALVAMEPPVSFDADSIRDEKVKVLKALRPIDPDDNN--TVRGQYGAGEIGGVSVPGYLEEEGvdKDSNTETFAA 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 319 IKAEVANWRWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDESAGPMT-ANQLVIRLQPDEGVKQWIMIKDPGpGGMR 397
Cdd:TIGR00871 317 LKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRDVPSLLFKANERDANpRNALVIRIQPDEGVYLKFNAKKPG-LNFE 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 398 LRHIPLDMTFADAFEVRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWA-NNQQSAQGYTAGTWGPSSSIA 476
Cdd:TIGR00871 396 TRPVKLDFSYASRFGELLPEAYERLLLDALLGDHTLFARDDEVEEAWRIVTPILEAWAaNKGPSPPNYPAGSWGPKEADE 475

                         490
                  ....*....|.
gi 1949155666 477 LIERDGRTWHE 487
Cdd:TIGR00871 476 LIRKDGRSWRK 486
G6PD_C pfam02781
Glucose-6-phosphate dehydrogenase, C-terminal domain;
190-486 0e+00

Glucose-6-phosphate dehydrogenase, C-terminal domain;


Pssm-ID: 460694  Cd Length: 295  Bit Score: 513.53  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 190 MALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALRDMVQNHMLQLLCLTAMEPPSSMEADAVRDEKLKI 269
Cdd:pfam02781   1 LVLRFANAIFEPLWNRNYIDHVQITVAETLGVEGRGGYYDQAGALRDMVQNHLLQLLALVAMEPPVSFDAEDIRDEKVKV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 270 LRSLRRITDSDASKLTVRGQYRAGASPSGAVRGYAEELG--DRSDTETFVAIKAEVANWRWAGVPFYLRTGKRLAERVSE 347
Cdd:pfam02781  81 LRSLRPITPEDVEDNVVRGQYGAGWIGGEPVPGYREEEGvpPDSRTETFAALKLFIDNWRWAGVPFYLRTGKRLPERVTE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 348 ICIQFKPVPHVVFDESaGPMTANQLVIRLQPDEGVKQWIMIKDPGPgGMRLRHIPLDMTFADAFEVRNPDAYERLIMDVV 427
Cdd:pfam02781 161 IRIQFKDVPHNLFRDP-GTLPPNELVIRIQPDEGIYLKFNAKVPGL-GMRLRPVELDFSYSDRFGERIPEAYERLLLDVM 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1949155666 428 RGNQTLFMRRDEIEAAWEWIDPIHAAWANNQqsAQGYTAGTWGPSSSIALIERDGRTWH 486
Cdd:pfam02781 239 RGDQTLFVRSDEVEAAWRIVDPILEAWDEEK--PPPYPAGSWGPKAADELLARDGRKWR 295
 
Name Accession Description Interval E-value
Zwf COG0364
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ...
 3-488 0e+00

Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440133 [Multi-domain]  Cd Length: 495  Bit Score: 872.86  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666   3 SQIIPVDPFDFVIFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFVKKEeIDNDQLE 82
Cdd:COG0364     2 TQMRPAEPCDLVIFGATGDLARRKLLPALYNLYRDGLLPEGFRIIGVARRDWSDEEFREEVREALEEFSRKP-FDEEVWE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  83 LFLARLSYRQVNAMSGEGFEGLKEALSE-----SKAVRVFYLAVAPNLFGDIAKNLAAHDLNK--GDVRIVVEKPIGRDQ 155
Cdd:COG0364    81 RFLERLHYVSGDFTDPEGYERLKELLEEldeerTPGNRVFYLATPPSLFGPICENLGAAGLATegGWRRVVIEKPFGHDL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 156 ASARQLNDAIGEVFDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALR 235
Cdd:COG0364   161 ASARELNDELGRVFDESQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVGVEGRGGYYDGAGALR 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 236 DMVQNHMLQLLCLTAMEPPSSMEADAVRDEKLKILRSLRRITDSDASKLTVRGQYRAGASPSGAVRGYAEELG--DRSDT 313
Cdd:COG0364   241 DMVQNHLLQLLCLVAMEPPASLDADAIRDEKVKVLRALRPITPEDVAENTVRGQYTAGWIGGEPVPGYREEPGvaPDSTT 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 314 ETFVAIKAEVANWRWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDESAGPMTANQLVIRLQPDEGVKQWIMIKDPGP 393
Cdd:COG0364   321 ETFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKPVPHSLFRETAEELPPNRLVIRIQPDEGISLRFNAKVPGL 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 394 gGMRLRHIPLDMTFADAFEVRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWANNQQSAQGYTAGTWGPSS 473
Cdd:COG0364   401 -GMRLRPVSLDFSYSDAFGERSPEAYERLLLDVMRGDQTLFMRRDEVEAAWRWVDPILEAWAEEPEPPPPYPAGSWGPEA 479

                         490
                  ....*....|....*
gi 1949155666 474 SIALIERDGRTWHES 488
Cdd:COG0364   480 ADALLARDGRSWREP 494
PRK05722 PRK05722
glucose-6-phosphate 1-dehydrogenase; Validated
 3-487 0e+00

glucose-6-phosphate 1-dehydrogenase; Validated


Pssm-ID: 235579 [Multi-domain]  Cd Length: 495  Bit Score: 835.17  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666   3 SQIIPVDPFDFVIFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFVKkEEIDNDQLE 82
Cdd:PRK05722    2 RLPRTAEPCDLVIFGATGDLARRKLLPALYNLYKAGLLPEDFRIIGVARRDWSDEDFREVVREALKEFAR-TPFDEEVWE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  83 LFLARLSYRQVNAMSGEGFEGLKEALSE------SKAVRVFYLAVAPNLFGDIAKNLAAHDLNK--GDVRIVVEKPIGRD 154
Cdd:PRK05722   81 RFLSRLYYVSGDVTDPESYERLKELLEEldeergTGGNRVFYLATPPSLFGTICENLAAAGLNEggGWRRVVIEKPFGHD 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 155 QASARQLNDAIGEVFDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGAL 234
Cdd:PRK05722  161 LASARELNDQVGEVFKEEQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVGVEGRGGYYDKSGAL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 235 RDMVQNHMLQLLCLTAMEPPSSMEADAVRDEKLKILRSLRRITDSDASKLTVRGQYRAGASPSGAVRGYAEELG--DRSD 312
Cdd:PRK05722  241 RDMVQNHLLQLLALVAMEPPASLDADSIRDEKVKVLRALRPITPEDVKENTVRGQYTAGWIGGKPVPGYREEEGvnPDST 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 313 TETFVAIKAEVANWRWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDESAGPMTANQLVIRLQPDEGVKQWIMIKDPG 392
Cdd:PRK05722  321 TETFVALKLEIDNWRWAGVPFYLRTGKRLPKKVTEIVIVFKPPPHNLFEESAEELGPNKLVIRIQPDEGISLRFNAKVPG 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 393 PgGMRLRHIPLDMTFADAFEVRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWANNQQSAQGYTAGTWGPS 472
Cdd:PRK05722  401 E-GMELRPVKLDFSYSEAFGEASPEAYERLLLDVMLGDQTLFVRRDEVEAAWKWVDPILEAWEADGGPPPPYPAGTWGPE 479

                         490
                  ....*....|....*
gi 1949155666 473 SSIALIERDGRTWHE 487
Cdd:PRK05722  480 AADALLARDGRSWRE 494
PRK12853 PRK12853
glucose-6-phosphate dehydrogenase;
7-489 0e+00

glucose-6-phosphate dehydrogenase;


Pssm-ID: 237233 [Multi-domain]  Cd Length: 482  Bit Score: 677.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666   7 PVDPFDFVIFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFVKKEeIDNDQLELFLA 86
Cdd:PRK12853    5 PAPPCTLVIFGATGDLARRKLLPALYRLARAGLLPEDLRIIGVGRDDWSDEQWRARVRESLRAFGADG-FDDAVWDRLAA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  87 RLSYRQVNAMSGEGFEGLKEALSESkAVRVFYLAVAPNLFGDIAKNLAAHDLNKGDVRIVVEKPIGRDQASARQLNDAIG 166
Cdd:PRK12853   84 RLSYVQGDVTDPADYARLAEALGPG-GNPVFYLAVPPSLFAPVVENLGAAGLLPEGRRVVLEKPFGHDLASARALNATLA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 167 EVFDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALRDMVQNHMLQLL 246
Cdd:PRK12853  163 KVFDEDQIYRIDHFLGKETVQNLLALRFANALLEPLWNRNHIDHVQITVAETLGVEGRGGFYDATGALRDMVQNHLLQLL 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 247 CLTAMEPPSSMEADAVRDEKLKILRSLRRITDSDASklTVRGQYRAGASPSGAVRGYAEELG--DRSDTETFVAIKAEVA 324
Cdd:PRK12853  243 ALVAMEPPASFDADAVRDEKAKVLRAIRPLDPDDVH--TVRGQYTAGTVGGEPVPGYREEPGvdPDSRTETFVALKLEID 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 325 NWRWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDEsAGPMTANQLVIRLQPDEGVKQWIMIKDPGPgGMRLRHIPLD 404
Cdd:PRK12853  321 NWRWAGVPFYLRTGKRLAERRTEIVITFKPVPHALFRG-TGVEPPNRLVIRLQPDEGISLELNVKRPGP-GMRLRPVELD 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 405 MTFADafEVRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWANNQQSAQGYTAGTWGPSSSIALIERDGRT 484
Cdd:PRK12853  399 ADYAD--DERPLEAYERLLLDVLRGDPTLFVRADEVEAAWRIVDPVLDAWAADPVPPHEYPAGSWGPAAADALLARDGRG 476


                  ....*
gi 1949155666 485 WHESV 489
Cdd:PRK12853  477 WREPA 481
zwf TIGR00871
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ...
 9-487 0e+00

glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273312 [Multi-domain]  Cd Length: 487  Bit Score: 615.48  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666   9 DPFDFVIFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFVKKEeiDNDQLELFLARL 88
Cdd:TIGR00871   1 DPCILVIFGASGDLARKKLFPALYRLFRNGLLPPDFRIVGVARRDWSVEEFRKVVREAIIKFETDE--IDEQWDEFAQRL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  89 SYRQVNAMSGEGFEGLKEALSES------KAVRVFYLAVAPNLFGDIAKNLAAHDLNK-GDV-RIVVEKPIGRDQASARQ 160
Cdd:TIGR00871  79 SYVSGDVDDDESYDSLAELLEQLdktygtEGNRLFYLATPPSLFGTIIKQLKKHGLNEqGKWsRVVVEKPFGHDLASAQE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 161 LNDAIGEVFDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALRDMVQN 240
Cdd:TIGR00871 159 LNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQIFEPLWNRRYIDHVQITVAESFGVEGRGGYYDKSGALRDMVQN 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 241 HMLQLLCLTAMEPPSSMEADAVRDEKLKILRSLRRITDSDASklTVRGQYRAGASPSGAVRGYAEELG--DRSDTETFVA 318
Cdd:TIGR00871 239 HLLQLLALVAMEPPVSFDADSIRDEKVKVLKALRPIDPDDNN--TVRGQYGAGEIGGVSVPGYLEEEGvdKDSNTETFAA 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 319 IKAEVANWRWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDESAGPMT-ANQLVIRLQPDEGVKQWIMIKDPGpGGMR 397
Cdd:TIGR00871 317 LKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRDVPSLLFKANERDANpRNALVIRIQPDEGVYLKFNAKKPG-LNFE 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 398 LRHIPLDMTFADAFEVRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWA-NNQQSAQGYTAGTWGPSSSIA 476
Cdd:TIGR00871 396 TRPVKLDFSYASRFGELLPEAYERLLLDALLGDHTLFARDDEVEEAWRIVTPILEAWAaNKGPSPPNYPAGSWGPKEADE 475

                         490
                  ....*....|.
gi 1949155666 477 LIERDGRTWHE 487
Cdd:TIGR00871 476 LIRKDGRSWRK 486
PRK12854 PRK12854
glucose-6-phosphate 1-dehydrogenase; Provisional
 7-488 0e+00

glucose-6-phosphate 1-dehydrogenase; Provisional


Pssm-ID: 237234 [Multi-domain]  Cd Length: 484  Bit Score: 523.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666   7 PVDPFDFVIFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFVKKEeIDNDQLELFLA 86
Cdd:PRK12854    8 PAPPTVFVLFGATGDLAKRKLLPGLFHLARAGLLPPDWRIVGTGRGDVSAEAFREHARDALDEFGARK-LDDGEWARFAK 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  87 RLSYRQVNAMSGEGfEGLKEALSESKA------VRVFYLAVAPNLFGDIAKNLAAHDLNKGDvRIVVEKPIGRDQASARQ 160
Cdd:PRK12854   87 RLRYVPGGFLSAGP-GALAAAVAAARAelggdaRLVHYLAVPPSAFLDVTRALGEAGLAEGS-RVVMEKPFGTDLASAEA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 161 LNDAIGEVFDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALRDMVQN 240
Cdd:PRK12854  165 LNAAVHEVFDESQIFRIDHFLGKEAAQNILAFRFANGLFEPIWNREFIDHVQIDVPETLGVDTRAAFYDATGAYRDMVVT 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 241 HMLQLLCLTAMEPPSSMEADAVRDEKLKILRSLRRItdsDASKLtVRGQYragaspsgavRGYAEELG--DRSDTETFVA 318
Cdd:PRK12854  245 HLFQVLAFVAMEPPTALEPDAISEEKNKVFRSMRPL---DPAEV-VRGQY----------SGYRDEPGvaPDSTTETFVA 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 319 IKAEVANWRWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDE-SAGPMTANQLVIRLQPDEGVKQWIMIKDPGPgGMR 397
Cdd:PRK12854  311 LKVWIDNWRWAGVPFYLRTGKRMAEGQRIISIAFREPPYSMFPAgSVGAQGPDHLTFDLADNSKVSLSFYGKRPGP-GMR 389

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 398 LrhIPLDMTFA--DAFEVRNP-DAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIhaawANNQQSAQGYTAGTWGPSSS 474
Cdd:PRK12854  390 L--DKLSLQFSlkDTGPKGDVlEAYERLILDALRGDHTLFTTADGIESLWEVSQPL----LEDPPPVKPYAPGSWGPNAI 463

                         490       500
                  ....*....|....*....|
gi 1949155666 475 IALIERDG------RTWHES 488
Cdd:PRK12854  464 HQLAAPDAwrlpfeREWREL 483
G6PD_C pfam02781
Glucose-6-phosphate dehydrogenase, C-terminal domain;
190-486 0e+00

Glucose-6-phosphate dehydrogenase, C-terminal domain;


Pssm-ID: 460694  Cd Length: 295  Bit Score: 513.53  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 190 MALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALRDMVQNHMLQLLCLTAMEPPSSMEADAVRDEKLKI 269
Cdd:pfam02781   1 LVLRFANAIFEPLWNRNYIDHVQITVAETLGVEGRGGYYDQAGALRDMVQNHLLQLLALVAMEPPVSFDAEDIRDEKVKV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 270 LRSLRRITDSDASKLTVRGQYRAGASPSGAVRGYAEELG--DRSDTETFVAIKAEVANWRWAGVPFYLRTGKRLAERVSE 347
Cdd:pfam02781  81 LRSLRPITPEDVEDNVVRGQYGAGWIGGEPVPGYREEEGvpPDSRTETFAALKLFIDNWRWAGVPFYLRTGKRLPERVTE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 348 ICIQFKPVPHVVFDESaGPMTANQLVIRLQPDEGVKQWIMIKDPGPgGMRLRHIPLDMTFADAFEVRNPDAYERLIMDVV 427
Cdd:pfam02781 161 IRIQFKDVPHNLFRDP-GTLPPNELVIRIQPDEGIYLKFNAKVPGL-GMRLRPVELDFSYSDRFGERIPEAYERLLLDVM 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1949155666 428 RGNQTLFMRRDEIEAAWEWIDPIHAAWANNQqsAQGYTAGTWGPSSSIALIERDGRTWH 486
Cdd:pfam02781 239 RGDQTLFVRSDEVEAAWRIVDPILEAWDEEK--PPPYPAGSWGPKAADELLARDGRKWR 295
PTZ00309 PTZ00309
glucose-6-phosphate 1-dehydrogenase; Provisional
 13-482 2.74e-142

glucose-6-phosphate 1-dehydrogenase; Provisional


Pssm-ID: 240353 [Multi-domain]  Cd Length: 542  Bit Score: 419.15  E-value: 2.74e-142
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  13 FVIFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQayRDFARAAITSFVKKEEIDNDQLELFLARLSYRQ 92
Cdd:PTZ00309   57 IIVLGASGDLAKKKTFPALFQLYCEGLLPSEVNIVGYARSKMSDV--ERWKKETLARFFKRLDDRECHLEQFLKHISYIS 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  93 VNAMSGEGFEGLKEALS--ESKAV-------RVFYLAVAPNLFGDIAKNLAAHDLNK-GDVRIVVEKPIGRDQASARQLN 162
Cdd:PTZ00309  135 GSYDEDEDFKRLNKLIErmEEAFQgpekggnRLFYLALPPSVFASVCEGIHRGCMSKnGWVRVIVEKPFGRDLESSEELS 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 163 DAIGEVFDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALRDMVQNHM 242
Cdd:PTZ00309  215 NQLEPLFDESQLYRIDHYLGKEMVQNLIVLRFANRVFEPLWNRNNIACVQITFKEDIGTEGRGGYFDSYGIIRDVMQNHL 294

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 243 LQLLCLTAMEPPSSMEADAVRDEKLKILRSLRRITDSDasklTVRGQYRagASPSGAVRGYAEELG--DRSDTETFVAIK 320
Cdd:PTZ00309  295 LQILALLAMEKPVSLSAEDIRDEKVKVLKCIEPIKMEE----CVLGQYT--ASADGSIPGYLEDEGvpKDSTTPTFAAAV 368

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 321 AEVANWRWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFdeSAGPMTANQLVIRLQPDEGVKQWIMIKDPGPGGmRLRH 400
Cdd:PTZ00309  369 LHINNDRWEGVPFILEAGKALEERYVEIRIQFKGVDEFRP--SGDDTQRNELVIRAQPSEAMYLKITAKVPGLSN-DLHQ 445

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 401 IPLDMTFADAFEVRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWANNQQSAQGYTAGTWGPSSSIALIER 480
Cdd:PTZ00309  446 TELDLTYKTRYNVRLPDAYERLILDALLGDSTNFVRKDELDVAWRIFTPLLHQIDRGEVKPEPYPFGSRGPKEADELIKK 525


                  ..
gi 1949155666 481 DG 482
Cdd:PTZ00309  526 NG 527
PLN02539 PLN02539
glucose-6-phosphate 1-dehydrogenase
 14-482 1.26e-124

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 178154 [Multi-domain]  Cd Length: 491  Bit Score: 372.52  E-value: 1.26e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  14 VIFGGTGDLAERKLLPALYQRQMAGQFQELT-RIIGASRSPLSDQAYRDFARAAitsFVKKEEIDNDQLELFLARLSYRQ 92
Cdd:PLN02539   21 IVLGASGDLAKKKTFPALFNLYRQGFLPPDEvHIFGYARSKITDEELRDRIRGY---LKDEKNAPAEAVSKFLQLIKYVS 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  93 VNAMSGEGFEGLKEALSE---------SKAVRVFYLAVAPNLFGDIAKNLAAHDLNKGDV--RIVVEKPIGRDQASARQL 161
Cdd:PLN02539   98 GAYDSEEGFRRLDKEISEheisknsaeGSSRRLFYLALPPSVYPPVCKMIKKCCMNKSGLwtRIVVEKPFGKDLESAEEL 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 162 NDAIGEVFDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALRDMVQNH 241
Cdd:PLN02539  178 SSQIGELFDESQLYRIDHYLGKELVQNLLVLRFANRFFLPLWNRDNIANVQIVFREDFGTEGRGGYFDEYGIIRDIIQNH 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 242 MLQLLCLTAMEPPSSMEADAVRDEKLKILRSLRRITDSDasklTVRGQYragaspsgavRGYAEE--LGDRSDTETFVAI 319
Cdd:PLN02539  258 LLQVLCLVAMEKPVSLKPEHIRDEKVKVLQSVEPIKDEE----VVLGQY----------EGYRDDptVPDDSNTPTFASV 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 320 KAEVANWRWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDESAgpMTANQLVIRLQPDEGVKQWIMIKDPGPgGMRLR 399
Cdd:PLN02539  324 VLRINNERWEGVPFILKAGKALDSRKAEIRVQFKDVPGDIFKCQK--QGRNEFVIRLQPSEAMYMKLTVKQPGL-EMSTV 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 400 HIPLDMTFADAFE-VRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWANNQQSAQGYTAGTWGPSSSIALI 478
Cdd:PLN02539  401 QSELDLSYGQRYQdVVIPEAYERLILDTIRGDQQHFVRRDELKAAWEIFTPLLHRIDAGKVKPIPYKQGSRGPAEADELL 480


                  ....
gi 1949155666 479 ERDG 482
Cdd:PLN02539  481 EKAG 484
PLN02333 PLN02333
glucose-6-phosphate 1-dehydrogenase
 15-485 3.49e-112

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 215191 [Multi-domain]  Cd Length: 604  Bit Score: 344.27  E-value: 3.49e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  15 IFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFVKKEEIDNDQLELFLARLSYRQVN 94
Cdd:PLN02333  122 VVGASGDLAKKKIFPALFALYYEGCLPEHFTIFGYARSKMTDAELRNMVSKTLTCRIDKRENCGEKMEEFLKRCFYHSGQ 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  95 AMSGEGFEGLKEALSESKAVRV----FYLAVAPNLFGDIAK--NLAAHDLNkGDVRIVVEKPIGRDQASARQLNDAIGEV 168
Cdd:PLN02333  202 YDSQEHFAELDKKLKEHEGGRVsnrlFYLSIPPNIFVDAVKcaSSSASSVN-GWTRVIVEKPFGRDSESSAALTKSLKQY 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 169 FDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALRDMVQNHMLQLLCL 248
Cdd:PLN02333  281 LEEDQIFRIDHYLGKELVENLSVLRFSNLIFEPLWSRQYIRNVQFIFSEDFGTEGRGGYFDNYGIIRDIMQNHLLQILAL 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 249 TAMEPPSSMEADAVRDEKLKILRSLRRITDSDasklTVRGQYRAGASPSGAVRGYAEE--LGDRSDTETFVAIKAEVANW 326
Cdd:PLN02333  361 FAMETPVSLDAEDIRNEKVKVLRSMRPIQLED----VVIGQYKSHTKGGVTYPAYTDDktVPKGSLTPTFAAAALFIDNA 436

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 327 RWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDESAGP---MTANQLVIRLQPDEGVkqWIMIKDPGPG-GMRLRHIP 402
Cdd:PLN02333  437 RWDGVPFLMKAGKALHTKSAEIRVQFRHVPGNLYNRNFGTdldQATNELVIRVQPDEAI--YLKINNKVPGlGMRLDRSN 514

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 403 LDMTFADAFEVRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWANNQQSAQGYTAGTWGPSSSIALIERDG 482
Cdd:PLN02333  515 LNLLYAARYSKEIPDAYERLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPEYYPYGSRGPVGAHYLAARYK 594


                  ...
gi 1949155666 483 RTW 485
Cdd:PLN02333  595 VRW 597
PLN02640 PLN02640
glucose-6-phosphate 1-dehydrogenase
 15-485 4.93e-111

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 215344 [Multi-domain]  Cd Length: 573  Bit Score: 340.07  E-value: 4.93e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  15 IFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFVKKEEIDNDQLELFLARLSYRQVN 94
Cdd:PLN02640   93 VVGASGDLAKKKIFPALFALFYEDWLPENFTVFGYARTKLTDEELRDMISSTLTCRIDQRENCGDKMDQFLKRCFYHSGQ 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  95 AMSGEGFEGLKEALSESKA----VRVFYLAVAPNLFGDIAK--NLAAHDLNkGDVRIVVEKPIGRDQASARQLNDAIGEV 168
Cdd:PLN02640  173 YDSEEDFAELNKKLKEKEAgklsNRLFYLSIPPNIFVDVVRcaSLRASSEN-GWTRVIVEKPFGRDSESSGELTRCLKQY 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 169 FDETQIFRIDHYLGKETVQNVMALRFANALYEPLWNSAHIDHVQITVAETVGLEDRVSYYDKAGALRDMVQNHMLQLLCL 248
Cdd:PLN02640  252 LTEEQIFRIDHYLGKELVENLSVLRFSNLVFEPLWSRNYIRNVQLIFSEDFGTEGRGGYFDNYGIIRDIMQNHLLQILAL 331

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 249 TAMEPPSSMEADAVRDEKLKILRSLRRITDSDasklTVRGQYRAGASPSGAVRGYAEE--LGDRSDTETFVAIKAEVANW 326
Cdd:PLN02640  332 FAMETPVSLDAEDIRNEKVKVLRSMKPLQLED----VIVGQYKGHSKGGKSYPAYTDDptVPKHSLTPTFAAAALFINNA 407

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 327 RWAGVPFYLRTGKRLAERVSEICIQFKPVPHVVFDESAGP---MTANQLVIRLQPDEGVkqWIMIKDPGPG-GMRLRHIP 402
Cdd:PLN02640  408 RWDGVPFLMKAGKALHTRRAEIRVQFRHVPGNLYKRNFGTdldKATNELVLRVQPDEAI--YLKINNKVPGlGMRLDRSD 485

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666 403 LDMTFADAFEVRNPDAYERLIMDVVRGNQTLFMRRDEIEAAWEWIDPIHAAWANNQQSAQGYTAGTWGPSSSIALIERDG 482
Cdd:PLN02640  486 LNLLYRARYPREIPDAYERLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPELYPYGSRGPVGAHYLAAKYN 565


                  ...
gi 1949155666 483 RTW 485
Cdd:PLN02640  566 VRW 568
G6PD_N pfam00479
Glucose-6-phosphate dehydrogenase, NAD binding domain;
14-188 8.39e-85

Glucose-6-phosphate dehydrogenase, NAD binding domain;


Pssm-ID: 459827 [Multi-domain]  Cd Length: 178  Bit Score: 258.89  E-value: 8.39e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  14 VIFGGTGDLAERKLLPALYQRQMAGQFQELTRIIGASRSPLSDQAYRDFARAAITSFvkkEEIDNDQLELFLARLSYRQV 93
Cdd:pfam00479   1 VIFGATGDLAKRKLFPALYNLYRDGLLPEGFRIIGVARRDLSDEEFRERVREALKEF---KELDEEKWDRFLERLHYVSG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1949155666  94 NAMSGEGFEGLKEALSES----KAVRVFYLAVAPNLFGDIAKNLAAHDLN--KGDVRIVVEKPIGRDQASARQLNDAIGE 167
Cdd:pfam00479  78 DFDDPESYEKLKERLEEHedetRGNRLFYLAVPPSLFGPIAENLGRAGLSeeGGWRRVVIEKPFGHDLESARELNDQLAK 157

                         170       180
                  ....*....|....*....|.
gi 1949155666 168 VFDETQIFRIDHYLGKETVQN 188
Cdd:pfam00479 158 VFKEEQIYRIDHYLGKETVQN 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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