|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
81-577 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 727.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 81 KPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSggRLYLQT 160
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP--FSLNHE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 161 RgSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILrTGFRQVVQGLLSE--TYLEAHR 238
Cdd:smart00350 79 R-STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP-YGFKLNTVKGLPVfaTYIEANH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 239 IVK--MNKSEDDESGA----GELTREELRQIAE-EDFYEKLAASIAPEINGHEDVKKALLLLLVGGVDQS-PRGMKIRGN 310
Cdd:smart00350 157 VRKldYKRSFEDSSFSvqslSDEEEEEIRKLSKdPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNlPDGMKIRGD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 311 INICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEAD 390
Cdd:smart00350 237 INILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 391 RTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLA 470
Cdd:smart00350 317 RTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 471 QHITYVHQHSR-QPPSQFE-PLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDAT--YTSARTLLAI 545
Cdd:smart00350 397 KHVVDLHRYSHpEEDEAFEpPLSQEKLRKYIAYAREKiKPKLSEEAADKLVKAYVDLRKEDSQTESRSsiPITVRQLESI 476
|
490 500 510
....*....|....*....|....*....|..
gi 194375542 546 LRLSTALARLRMVDVVEKEDVNEAIRLMEMSK 577
Cdd:smart00350 477 IRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
271-576 |
0e+00 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 607.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 271 KLAASIAPEINGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGL 350
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRGDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 351 TAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGR 430
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 431 YNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVP 510
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDFEPLDPKLLRAYIALAKRKRPTVP 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 194375542 511 ESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 576
Cdd:cd17758 241 PALADYIVQAYVEMRQEAKRSKDFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
79-574 |
3.58e-177 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 519.74 E-value: 3.58e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 79 SNKPRV--IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQtnrsgGRL 156
Cdd:COG1241 88 TNLPETvpIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHECPGCGRQ-----GPF 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 157 YLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIflpiLRTGFRQVVQGLLS--ETYL 234
Cdd:COG1241 163 KLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGI----LRIEQRTSGRGKSTifDLYL 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 235 EAHRIVKMNKSEDDEsgagELTREELRQIAE----EDFYEKLAASIAPEINGHEDVKKALLL-----LLVGGVDqsprGM 305
Cdd:COG1241 239 EANSIEVEEKEFEEI----EITEEDEEKIKElskdPDIYEKIIASIAPSIYGYEEIKEAIALqlfggVPKVLPD----GS 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 306 KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVS-GELTLEGGALVLADQGVCCIDEFD 384
Cdd:COG1241 311 RIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFGtGRWTLEAGALVLADGGLACIDELD 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 385 KMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRD 464
Cdd:COG1241 391 KMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEE 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 465 NDLRLAQHITYVHQHSRQPPSQFE--------PLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDAT 535
Cdd:COG1241 471 RDRELARHILKVHRAGELLEQEIEeeteevkpEIDPDLLRKYIAYARRNvFPVLTEEAKDLIEDFYVDMRKKGEDEDSPV 550
|
490 500 510
....*....|....*....|....*....|....*....
gi 194375542 536 YTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLME 574
Cdd:COG1241 551 PITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVD 589
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
11-574 |
6.98e-168 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 495.98 E-value: 6.98e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 11 RMPGATRSSLLMPYKEREVVNKDVLDVYIEH----------RLMMEQRSRDPGMVRSPQNQYPaelmrRFElyfqgpssN 80
Cdd:NF040949 27 EMIAMRKRSLVVDFNDLYMFDPELADLLIEKpdevlpaaskALKEIVEEEDPEYAEEVAKFHV-----RFR--------N 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 81 KPRV--IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPiQSPTFMPLIMCPSQECQTNRSGGRLYL 158
Cdd:NF040949 94 LPRTvpLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWP-EEEEESYEIVEPPTVCPVCGKPGSFRL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 159 QTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSeTYLEAHR 238
Cdd:NF040949 173 LQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSLKKGSRPIFK-NYIEANH 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 239 IVKMNKsEDDESgagELTREELRQIAE----EDFYEKLAASIAPEINGHEDVKKALLLLL-VGGVDQSPRGMKIRGNINI 313
Cdd:NF040949 252 IEVSQK-ELEEV---EITEEDEEKILElakdPWIREKIIASIAPSIYGHWEIKEAIALLLfGGVPKVLPDGTRIRGDIHV 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 314 CLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTA 393
Cdd:NF040949 328 LIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSA 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 394 IHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHI 473
Cdd:NF040949 408 IHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHI 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 474 TYVHQHSrqppSQFEP-LDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKD---ATYTSARTLLAILRL 548
Cdd:NF040949 488 LDVHSGK----EKVKPeIDPDLLKKYIAYARKYvRPKLTEEAKKLIEDFYVEMRKSSKSSEDpdsPIPITARQLEALIRL 563
|
570 580
....*....|....*....|....*.
gi 194375542 549 STALARLRMVDVVEKEDVNEAIRLME 574
Cdd:NF040949 564 SEAHAKMRLKDEVTAEDAERAIRLML 589
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
258-477 |
3.13e-132 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 387.66 E-value: 3.13e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 258 EELRQIA-EEDFYEKLAASIAPEINGHEDVKKALLLLLVG-GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAP 335
Cdd:pfam00493 3 EEIKELAkRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGgVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 336 RSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLN 415
Cdd:pfam00493 83 RAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLN 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 194375542 416 ARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVH 477
Cdd:pfam00493 163 ARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
73-576 |
4.27e-85 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 286.12 E-value: 4.27e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 73 YFQGPSSNKPRVIREVRADSvgkLVTVRGIVTRVSEVKPKMVVATYTC---DQCGAETYQPIQSPTFMPLIMCPSQE--- 146
Cdd:PTZ00111 209 LMNKPVSDCVGNLEPSMADS---LVQFSGTVVRQTWIVPEITMACFRCrgqKKIGLNDYQPCTCEHYEYVIQGEVNEpll 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 147 CQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIP-RSITVLVEGENTRI-------------------AQPGDH 206
Cdd:PTZ00111 286 CNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgLDNSVDNSGLNGEIymkdnevinlnlyddlidsVKTGDR 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 207 VSVTGIF--LPIlRTGFRQVVQGLLSETYLEA-H-RIVKMNKSEDDESG------AGELTREELRQIAE----EDFYEKL 272
Cdd:PTZ00111 366 VTVVGILkvTPI-RTSTTRRTLKSLYTYFVNViHvKVINSTNANQPEKGlkylgnENDFSDLQVYKILElsrnPMIYRIL 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 273 AASIAPEINGHEDVKK----------ALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTG 342
Cdd:PTZ00111 445 LDSFAPSIKARNNVKIgllcqlfsgnKNSSDFNKSPDACYKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSG 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 343 RGSSGVGLTAAV-LRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSIL 421
Cdd:PTZ00111 525 KSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAIL 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 422 AAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHI-----------------TY-------VH 477
Cdd:PTZ00111 605 ASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIakdfllphmtgsgndedTYdrsntmhVE 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 478 QHSRQPPSQFEPLDMKLMRRYIAMCR-EKQPMVPESLADYITAAYVEMRREAWASKD----------------------- 533
Cdd:PTZ00111 685 DESLRSEKDYNKNDLDMLRMYIKFSKlHCFPKLSDEAKKVITREYVKMRQGNFQTSNldelehaqedddddlyyqssgtr 764
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 194375542 534 ATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 576
Cdd:PTZ00111 765 MIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
81-577 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 727.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 81 KPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSggRLYLQT 160
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP--FSLNHE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 161 RgSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILrTGFRQVVQGLLSE--TYLEAHR 238
Cdd:smart00350 79 R-STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP-YGFKLNTVKGLPVfaTYIEANH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 239 IVK--MNKSEDDESGA----GELTREELRQIAE-EDFYEKLAASIAPEINGHEDVKKALLLLLVGGVDQS-PRGMKIRGN 310
Cdd:smart00350 157 VRKldYKRSFEDSSFSvqslSDEEEEEIRKLSKdPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNlPDGMKIRGD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 311 INICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEAD 390
Cdd:smart00350 237 INILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 391 RTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLA 470
Cdd:smart00350 317 RTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 471 QHITYVHQHSR-QPPSQFE-PLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDAT--YTSARTLLAI 545
Cdd:smart00350 397 KHVVDLHRYSHpEEDEAFEpPLSQEKLRKYIAYAREKiKPKLSEEAADKLVKAYVDLRKEDSQTESRSsiPITVRQLESI 476
|
490 500 510
....*....|....*....|....*....|..
gi 194375542 546 LRLSTALARLRMVDVVEKEDVNEAIRLMEMSK 577
Cdd:smart00350 477 IRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
271-576 |
0e+00 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 607.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 271 KLAASIAPEINGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGL 350
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRGDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 351 TAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGR 430
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 431 YNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVP 510
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDFEPLDPKLLRAYIALAKRKRPTVP 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 194375542 511 ESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 576
Cdd:cd17758 241 PALADYIVQAYVEMRQEAKRSKDFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
79-574 |
3.58e-177 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 519.74 E-value: 3.58e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 79 SNKPRV--IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQtnrsgGRL 156
Cdd:COG1241 88 TNLPETvpIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHECPGCGRQ-----GPF 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 157 YLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIflpiLRTGFRQVVQGLLS--ETYL 234
Cdd:COG1241 163 KLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGI----LRIEQRTSGRGKSTifDLYL 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 235 EAHRIVKMNKSEDDEsgagELTREELRQIAE----EDFYEKLAASIAPEINGHEDVKKALLL-----LLVGGVDqsprGM 305
Cdd:COG1241 239 EANSIEVEEKEFEEI----EITEEDEEKIKElskdPDIYEKIIASIAPSIYGYEEIKEAIALqlfggVPKVLPD----GS 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 306 KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVS-GELTLEGGALVLADQGVCCIDEFD 384
Cdd:COG1241 311 RIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFGtGRWTLEAGALVLADGGLACIDELD 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 385 KMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRD 464
Cdd:COG1241 391 KMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEE 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 465 NDLRLAQHITYVHQHSRQPPSQFE--------PLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDAT 535
Cdd:COG1241 471 RDRELARHILKVHRAGELLEQEIEeeteevkpEIDPDLLRKYIAYARRNvFPVLTEEAKDLIEDFYVDMRKKGEDEDSPV 550
|
490 500 510
....*....|....*....|....*....|....*....
gi 194375542 536 YTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLME 574
Cdd:COG1241 551 PITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVD 589
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
11-574 |
6.98e-168 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 495.98 E-value: 6.98e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 11 RMPGATRSSLLMPYKEREVVNKDVLDVYIEH----------RLMMEQRSRDPGMVRSPQNQYPaelmrRFElyfqgpssN 80
Cdd:NF040949 27 EMIAMRKRSLVVDFNDLYMFDPELADLLIEKpdevlpaaskALKEIVEEEDPEYAEEVAKFHV-----RFR--------N 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 81 KPRV--IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPiQSPTFMPLIMCPSQECQTNRSGGRLYL 158
Cdd:NF040949 94 LPRTvpLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWP-EEEEESYEIVEPPTVCPVCGKPGSFRL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 159 QTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSeTYLEAHR 238
Cdd:NF040949 173 LQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSLKKGSRPIFK-NYIEANH 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 239 IVKMNKsEDDESgagELTREELRQIAE----EDFYEKLAASIAPEINGHEDVKKALLLLL-VGGVDQSPRGMKIRGNINI 313
Cdd:NF040949 252 IEVSQK-ELEEV---EITEEDEEKILElakdPWIREKIIASIAPSIYGHWEIKEAIALLLfGGVPKVLPDGTRIRGDIHV 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 314 CLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTA 393
Cdd:NF040949 328 LIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSA 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 394 IHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHI 473
Cdd:NF040949 408 IHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHI 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 474 TYVHQHSrqppSQFEP-LDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKD---ATYTSARTLLAILRL 548
Cdd:NF040949 488 LDVHSGK----EKVKPeIDPDLLKKYIAYARKYvRPKLTEEAKKLIEDFYVEMRKSSKSSEDpdsPIPITARQLEALIRL 563
|
570 580
....*....|....*....|....*.
gi 194375542 549 STALARLRMVDVVEKEDVNEAIRLME 574
Cdd:NF040949 564 SEAHAKMRLKDEVTAEDAERAIRLML 589
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
271-576 |
8.54e-139 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 407.88 E-value: 8.54e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 271 KLAASIAPEINGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 349
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKIlEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 350 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 429
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 430 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHS-----RQPPSQFEPLDMKLMRRYIAMCRE 504
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSdpeeqVKPEEDGIPIDIELLRKYILYARQ 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 194375542 505 KQPMVPESLADYITAAYVEMRREAwASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 576
Cdd:cd17706 241 IHPKISEEAREKLVRWYVELRKES-ERRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
258-477 |
3.13e-132 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 387.66 E-value: 3.13e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 258 EELRQIA-EEDFYEKLAASIAPEINGHEDVKKALLLLLVG-GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAP 335
Cdd:pfam00493 3 EEIKELAkRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGgVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 336 RSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLN 415
Cdd:pfam00493 83 RAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLN 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 194375542 416 ARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVH 477
Cdd:pfam00493 163 ARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
271-573 |
1.24e-120 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 361.37 E-value: 1.24e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 271 KLAASIAPEINGHEDVKKALLLLL--VGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV 348
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLfgGTRKDFTKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 349 GLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAY 428
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 429 GRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREK-QP 507
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHIQDEVLDVEVLTDYISYAREHiHP 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194375542 508 MVPESLADYITAAYVEMRReAWASKDATYTSA-RTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 573
Cdd:cd17755 241 KLSEEAAQELVQAYVDMRK-MGSDARKRITATpRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLI 306
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
271-576 |
7.02e-120 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 359.39 E-value: 7.02e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 271 KLAASIAPEINGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 349
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRlPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 350 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 429
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 430 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSR--QPPSQFEP-LDMKLMRRYIAMCREK- 505
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARkaSQSQENEGeIPISKLKRYIAYCRAKc 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194375542 506 QPMVPESLADYITAAYVEMRREAWASKDATYTSA------RTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 576
Cdd:cd17756 241 APRLSEEAAEKLSNHYVTIRKDVRQNELESDNRSsipitvRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
270-573 |
4.33e-118 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 354.84 E-value: 4.33e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 270 EKLAASIAPEINGHEDVKKALLLLL-VGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV 348
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLfGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 349 GLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAY 428
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 429 GRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRqpPSQFEP-LDMKLMRRYIAMCREK-Q 506
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGE--MREIKPeIDPDLLRKYIAYARKNvR 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194375542 507 PMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 573
Cdd:cd17761 239 PVLTEEAKQLIKDFYVEMRKSGQETPSPVPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIM 305
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
271-576 |
1.95e-116 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 350.52 E-value: 1.95e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 271 KLAASIAPEINGHEDVKKALLLLLVG-GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 349
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGgVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 350 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 429
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 430 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHItyVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMV 509
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHI--VDLHSKREEAIEPPFTAEQLKRYIAYARTFKPKL 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 194375542 510 PESLADYITAAYVEMR-REAWASKDATY-TSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 576
Cdd:cd17757 239 TKEAKDELVEQYKELRqDDASGSTRSSYrITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
271-573 |
8.25e-116 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 349.44 E-value: 8.25e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 271 KLAASIAPEINGHEDVKKALLLLLVGGVDQSPRGM-KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 349
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKhRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 350 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 429
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 430 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHItyVHQHSRQPPS--------------------QFEP 489
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFV--VGSHVRSHPEndedregeeeknqrqrpketKVEP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 490 LDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDATYTsARTLLAILRLSTALARLRMVDVVEKEDVNE 568
Cdd:cd17753 239 IPQELLRKYIHYAREKvRPKLNQMDMDKVSRVYADLRKESMATGSLPIT-VRHLESIIRISEAHAKMHLREYVSEEDVDM 317
|
....*
gi 194375542 569 AIRLM 573
Cdd:cd17753 318 AIRVM 322
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
272-573 |
4.56e-112 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 338.67 E-value: 4.56e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 272 LAASIAPEINGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGL 350
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNlENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 351 TAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGR 430
Cdd:cd17754 82 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 431 YNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHsrqppsqfepldMKLMRRYIAMCREK-QPMV 509
Cdd:cd17754 162 YDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------IKFLRKYIHYAKERiKPKL 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194375542 510 PESLADYITAAYVEMRREAWASKDATYTS---ARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 573
Cdd:cd17754 230 TQEAAEYIAEEYADLRNDDNTKTDKARTSpitARTLETLIRLATAHAKARLSKTVDKVDAEVALNLL 296
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
73-576 |
4.27e-85 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 286.12 E-value: 4.27e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 73 YFQGPSSNKPRVIREVRADSvgkLVTVRGIVTRVSEVKPKMVVATYTC---DQCGAETYQPIQSPTFMPLIMCPSQE--- 146
Cdd:PTZ00111 209 LMNKPVSDCVGNLEPSMADS---LVQFSGTVVRQTWIVPEITMACFRCrgqKKIGLNDYQPCTCEHYEYVIQGEVNEpll 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 147 CQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIP-RSITVLVEGENTRI-------------------AQPGDH 206
Cdd:PTZ00111 286 CNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgLDNSVDNSGLNGEIymkdnevinlnlyddlidsVKTGDR 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 207 VSVTGIF--LPIlRTGFRQVVQGLLSETYLEA-H-RIVKMNKSEDDESG------AGELTREELRQIAE----EDFYEKL 272
Cdd:PTZ00111 366 VTVVGILkvTPI-RTSTTRRTLKSLYTYFVNViHvKVINSTNANQPEKGlkylgnENDFSDLQVYKILElsrnPMIYRIL 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 273 AASIAPEINGHEDVKK----------ALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTG 342
Cdd:PTZ00111 445 LDSFAPSIKARNNVKIgllcqlfsgnKNSSDFNKSPDACYKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSG 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 343 RGSSGVGLTAAV-LRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSIL 421
Cdd:PTZ00111 525 KSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAIL 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 422 AAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHI-----------------TY-------VH 477
Cdd:PTZ00111 605 ASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIakdfllphmtgsgndedTYdrsntmhVE 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 478 QHSRQPPSQFEPLDMKLMRRYIAMCR-EKQPMVPESLADYITAAYVEMRREAWASKD----------------------- 533
Cdd:PTZ00111 685 DESLRSEKDYNKNDLDMLRMYIKFSKlHCFPKLSDEAKKVITREYVKMRQGNFQTSNldelehaqedddddlyyqssgtr 764
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 194375542 534 ATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 576
Cdd:PTZ00111 765 MIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
272-576 |
5.22e-81 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 258.24 E-value: 5.22e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 272 LAASIAPEINGHEDVKKALLLLLV---GGVDQSprGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV 348
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAggvQRIDAS--GTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 349 GLTAAVLRDSvsGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAy 428
Cdd:cd17760 80 GLTVTAVKDG--GEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 429 GRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITyvhqHSRQPPSQFEPL-DMKLMRRYIAMCREKQP 507
Cdd:cd17760 157 GQYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL----ENKGEPSKSSKLwSMEKMRTYFCLIKNLRP 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 194375542 508 MVPESlADYITAAYVEMRREAwASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 576
Cdd:cd17760 233 VLSDE-ANAILLRYYQLQRQS-DCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
272-576 |
1.56e-72 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 235.89 E-value: 1.56e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 272 LAASIAPEINGHEDVKKALLLL----LVGGVDQSPRgMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSG 347
Cdd:cd17759 2 IVNSLCPAIYGHELVKAGLLLSlfggKQKYADDKNR-IPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 348 VGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEaDRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPA 427
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGS-QHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 428 YGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHityvhqhsrqppsqfepldMKLMRRYIAMCR-EKQ 506
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH-------------------HQLLRKYISYARqYVN 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 507 PMVPESLADYITAAYVEMRREAwASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 576
Cdd:cd17759 221 PVLSKDASEALQEFYLELRKQN-QLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
85-216 |
1.12e-51 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 174.21 E-value: 1.12e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 85 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTfmpliMCPSQECQtnrSGGRLYLQTRGSR 164
Cdd:pfam17207 2 IRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKITEPT-----KCPNPECG---NKDPFKLVHEKSK 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 194375542 165 FIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI 216
Cdd:pfam17207 74 FVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVV 125
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
494-577 |
1.73e-26 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 103.01 E-value: 1.73e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 494 LMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRL 572
Cdd:pfam17855 2 LLRKYIAYAREKiKPKLSEEAREKLVDAYVELRKESTGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIRL 81
|
....*
gi 194375542 573 MEMSK 577
Cdd:pfam17855 82 LKESL 86
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
312-451 |
1.17e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 45.36 E-value: 1.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 312 NICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSgvGLTAAVLRDSVS---GELTLEGGALVLADQ--GVCCIDEFDKm 386
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFYVQLTR--DTTEEDLFGRRNidpGGASWVDGPLVRAARegEIAVLDEINR- 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 194375542 387 AEADRTAI-HEVMEQQTISIAKAGILTTLNARC-SILAAANPAYGRYNPrrsleqniqLPAALLSRF 451
Cdd:pfam07728 78 ANPDVLNSlLSLLDERRLLLPDGGELVKAAPDGfRLIATMNPLDRGLNE---------LSPALRSRF 135
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
380-566 |
5.09e-05 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 45.54 E-value: 5.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 380 IDEFDKmaeAD-RT--AIHEVMEQQTISIAKAGIltTLNARCSILAAANP--AYGRYnprrsleqniQLPAALLSRFDL- 453
Cdd:COG0714 100 ADEINR---APpKTqsALLEAMEERQVTIPGGTY--KLPEPFLVIATQNPieQEGTY----------PLPEAQLDRFLLk 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194375542 454 LWLiqDRPDRDNDLRLaqhityVHQHSRQPPSQFEPLdmkLMRRYIAMCRE--KQPMVPESLADYITAAYVEMRREAWAS 531
Cdd:COG0714 165 LYI--GYPDAEEEREI------LRRHTGRHLAEVEPV---LSPEELLALQElvRQVHVSEAVLDYIVDLVRATREHPDLR 233
|
170 180 190
....*....|....*....|....*....|....*
gi 194375542 532 KDAtytSARTLLAILRLSTALARLRMVDVVEKEDV 566
Cdd:COG0714 234 KGP---SPRASIALLRAARALALLDGRDYVTPDDV 265
|
|
| |
