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Conserved domains on  [gi|1941156864|ref|WP_197020754|]
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FAD-dependent oxidoreductase [Selenomonas sp. AE3005]

Protein Classification

UDP-galactopyranose mutase( domain architecture ID 1904201)

UDP-galactopyranose mutase converts uridine diphosphogalactopyranose (UDP-GalP) to uridine diphosphogalactofuranose (UDP-GalF)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glf super family cl43185
UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];
1-91 7.88e-39

UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG0562:

Pssm-ID: 440328 [Multi-domain]  Cd Length: 365  Bit Score: 132.15  E-value: 7.88e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941156864   1 MEYLVVGAGLSGAVIARKLADN-GHKVTIWERRSHIGGNMYDYKDEYGINVHKYGPHTFHTNDK---NYMSSCFSMRN-G 75
Cdd:COG0562     3 YDYLIVGAGFFGAVFAERLAEElGKKVLVIDKRDHIGGNAYDEYDETGILVHKYGPHIFHTNNKrvwDYLSRFTEFNPyQ 82

                          90
                  ....*....|....*.
gi 1941156864  76 NRMHCNVGHKsMVNLP 91
Cdd:COG0562    83 HRVLANVDGQ-LYPLP 97
 
Name Accession Description Interval E-value
Glf COG0562
UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];
1-91 7.88e-39

UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440328 [Multi-domain]  Cd Length: 365  Bit Score: 132.15  E-value: 7.88e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941156864   1 MEYLVVGAGLSGAVIARKLADN-GHKVTIWERRSHIGGNMYDYKDEYGINVHKYGPHTFHTNDK---NYMSSCFSMRN-G 75
Cdd:COG0562     3 YDYLIVGAGFFGAVFAERLAEElGKKVLVIDKRDHIGGNAYDEYDETGILVHKYGPHIFHTNNKrvwDYLSRFTEFNPyQ 82

                          90
                  ....*....|....*.
gi 1941156864  76 NRMHCNVGHKsMVNLP 91
Cdd:COG0562    83 HRVLANVDGQ-LYPLP 97
UDP-GALP_mutase TIGR00031
UDP-galactopyranose mutase; This enzyme is involved in the conversion of UDP-GALP into ...
 2-74 4.01e-22

UDP-galactopyranose mutase; This enzyme is involved in the conversion of UDP-GALP into UDP-GALF through a 2-keto intermediate. It contains FAD as a cofactor. The gene is known as glf, ceoA, and rfbD. It is known experimentally in E. coli, Mycobacterium tuberculosis, and Klebsiella pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 272864 [Multi-domain]  Cd Length: 377  Bit Score: 88.30  E-value: 4.01e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1941156864   2 EYLVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYKDEyGINVHKYGPHTFHTNDK---NYMSSCFSMRN 74
Cdd:TIGR00031   3 DYIIVGAGLSGIVLANILAQLNKRVLVVEKRNHIGGNCYDEVDE-TILFHQYGPHIFHTNNQyvwDYISPFFELNN 77
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
5-67 2.08e-20

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 77.19  E-value: 2.08e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1941156864  5 VVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYkdEYGINVHKYGPHTFHTNDKNYMS 67
Cdd:pfam13450  1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSY--RVPGYVFDYGAHIFHGSDEPNVR 61
PLN02487 PLN02487
zeta-carotene desaturase
 5-58 2.14e-09

zeta-carotene desaturase


Pssm-ID: 215268 [Multi-domain]  Cd Length: 569  Bit Score: 52.50  E-value: 2.14e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYKDEYGiNVHKYGPHTF 58
Cdd:PLN02487   80 IIGAGLAGMSTAVELLDQGHEVDIYESRPFIGGKVGSFVDKNG-NHIEMGLHVF 132
 
Name Accession Description Interval E-value
Glf COG0562
UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];
1-91 7.88e-39

UDP-galactopyranose mutase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440328 [Multi-domain]  Cd Length: 365  Bit Score: 132.15  E-value: 7.88e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941156864   1 MEYLVVGAGLSGAVIARKLADN-GHKVTIWERRSHIGGNMYDYKDEYGINVHKYGPHTFHTNDK---NYMSSCFSMRN-G 75
Cdd:COG0562     3 YDYLIVGAGFFGAVFAERLAEElGKKVLVIDKRDHIGGNAYDEYDETGILVHKYGPHIFHTNNKrvwDYLSRFTEFNPyQ 82

                          90
                  ....*....|....*.
gi 1941156864  76 NRMHCNVGHKsMVNLP 91
Cdd:COG0562    83 HRVLANVDGQ-LYPLP 97
UDP-GALP_mutase TIGR00031
UDP-galactopyranose mutase; This enzyme is involved in the conversion of UDP-GALP into ...
 2-74 4.01e-22

UDP-galactopyranose mutase; This enzyme is involved in the conversion of UDP-GALP into UDP-GALF through a 2-keto intermediate. It contains FAD as a cofactor. The gene is known as glf, ceoA, and rfbD. It is known experimentally in E. coli, Mycobacterium tuberculosis, and Klebsiella pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 272864 [Multi-domain]  Cd Length: 377  Bit Score: 88.30  E-value: 4.01e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1941156864   2 EYLVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYKDEyGINVHKYGPHTFHTNDK---NYMSSCFSMRN 74
Cdd:TIGR00031   3 DYIIVGAGLSGIVLANILAQLNKRVLVVEKRNHIGGNCYDEVDE-TILFHQYGPHIFHTNNQyvwDYISPFFELNN 77
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
5-67 2.08e-20

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 77.19  E-value: 2.08e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1941156864  5 VVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYkdEYGINVHKYGPHTFHTNDKNYMS 67
Cdd:pfam13450  1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSY--RVPGYVFDYGAHIFHGSDEPNVR 61
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 1-62 7.61e-11

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 56.76  E-value: 7.61e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1941156864   1 MEYLVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYkdEYGINVHKYGPHTFHTND 62
Cdd:COG1232     2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGLIRTV--EVDGFRIDRGPHSFLTRD 61
PLN02487 PLN02487
zeta-carotene desaturase
 5-58 2.14e-09

zeta-carotene desaturase


Pssm-ID: 215268 [Multi-domain]  Cd Length: 569  Bit Score: 52.50  E-value: 2.14e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYKDEYGiNVHKYGPHTF 58
Cdd:PLN02487   80 IIGAGLAGMSTAVELLDQGHEVDIYESRPFIGGKVGSFVDKNG-NHIEMGLHVF 132
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
4-37 2.05e-08

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 49.92  E-value: 2.05e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGG 37
Cdd:COG1231    11 VIVGAGLAGLAAARELRKAGLDVTVLEARDRVGG 44
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 10-65 2.68e-08

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 49.41  E-value: 2.68e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1941156864  10 LSGAVIARKLADNGHKVTIWERRSHIGGNMYDYKDEyGINVHKyGPHTFHTNDKNY 65
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRTVRDD-GFLIEL-GAMWFHGAQPPL 54
PRK07233 PRK07233
hypothetical protein; Provisional
 5-67 4.76e-08

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 48.73  E-value: 4.76e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYKDEyGINVHKYGPHTFhTNDKNYMS 67
Cdd:PRK07233    4 IVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLAASFEFG-GLPIERFYHHIF-KSDEALLE 64
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 5-48 1.04e-07

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 47.87  E-value: 1.04e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMydykdEYGI 48
Cdd:PRK11749  145 VIGAGPAGLTAAHRLARKGYDVTIFEARDKAGGLL-----RYGI 183
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
4-39 1.93e-07

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 47.16  E-value: 1.93e-07
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNM 39
Cdd:COG1148   144 LVIGGGIAGMTAALELAEQGYEVYLVEKEPELGGRA 179
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 5-48 3.90e-07

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 46.28  E-value: 3.90e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMydykdEYGI 48
Cdd:COG0493   126 VVGSGPAGLAAAYQLARAGHEVTVFEALDKPGGLL-----RYGI 164
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 5-58 1.61e-06

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 44.46  E-value: 1.61e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1941156864   5 VVGAGLSG---AVIarkLADNGHKVTIWERRSHIGGNMYDYK-DEYGINVhkyGPHTF 58
Cdd:COG1233     8 VIGAGIGGlaaAAL---LARAGYRVTVLEKNDTPGGRARTFErPGFRFDV---GPSVL 59
PLN03000 PLN03000
amine oxidase
 4-47 1.86e-06

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 44.24  E-value: 1.86e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYKDEYG 47
Cdd:PLN03000  188 VIVGAGLSGLAAARQLMRFGFKVTVLEGRKRPGGRVYTKKMEAN 231
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 2-37 2.39e-06

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 43.93  E-value: 2.39e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1941156864   2 EYLVVGAGLSGAVIARKLADNGHKVTIWERRSHIGG 37
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGS 36
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 5-43 3.16e-06

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 43.61  E-value: 3.16e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRSHIGG-NMY---DYK 43
Cdd:PRK12810  148 VVGSGPAGLAAADQLARAGHKVTVFERADRIGGlLRYgipDFK 190
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 5-37 3.42e-06

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 43.30  E-value: 3.42e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1941156864   5 VVGAGLSG---AViarKLADNGHKVTIWERRSHIGG 37
Cdd:COG3349     8 VVGGGLAGlaaAV---ELAEAGFRVTLLEARPRLGG 40
PLN02576 PLN02576
protoporphyrinogen oxidase
 4-62 6.83e-06

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 42.69  E-value: 6.83e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941156864   4 LVVGAGLSGAVIARKLADN-GHKVTIWERRSHIGGNMYDyKDEYGInVHKYGPHTFHTND 62
Cdd:PLN02576   16 AVVGAGVSGLAAAYALASKhGVNVLVTEARDRVGGNITS-VSEDGF-IWEEGPNSFQPSD 73
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-32 7.96e-06

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 42.58  E-value: 7.96e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1941156864   1 MEYLVVGAGLSGAVIARKLADNGHKVTIWERR 32
Cdd:COG0665     3 ADVVVIGGGIAGLSTAYHLARRGLDVTVLERG 34
PLN02612 PLN02612
phytoene desaturase
 1-58 8.14e-06

phytoene desaturase


Pssm-ID: 215330 [Multi-domain]  Cd Length: 567  Bit Score: 42.52  E-value: 8.14e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1941156864   1 MEYLVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYKDEYGiNVHKYGPHTF 58
Cdd:PLN02612   94 LKVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKVAAWKDEDG-DWYETGLHIF 150
PLN02268 PLN02268
probable polyamine oxidase
 4-42 9.72e-06

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 42.37  E-value: 9.72e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMY-DY 42
Cdd:PLN02268    4 IVIGGGIAGIAAARALHDASFKVTLLESRDRIGGRVHtDY 43
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-41 1.17e-05

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 41.77  E-value: 1.17e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1941156864   1 MEYLVVGAGLSGAVIARKLADNGHKVTIWERRSHIGG----NMYD 41
Cdd:COG2072     7 VDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGtwrdNRYP 51
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 4-48 1.18e-05

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 42.17  E-value: 1.18e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMydykdEYGI 48
Cdd:PRK12771  141 AVIGGGPAGLSAAYHLRRMGHAVTIFEAGPKLGGMM-----RYGI 180
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 4-36 1.50e-05

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 41.46  E-value: 1.50e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIG 36
Cdd:COG0654     7 LIVGGGPAGLALALALARAGIRVTVVERAPPPR 39
COG3573 COG3573
Predicted oxidoreductase [General function prediction only];
4-37 1.86e-05

Predicted oxidoreductase [General function prediction only];


Pssm-ID: 442794 [Multi-domain]  Cd Length: 551  Bit Score: 41.32  E-value: 1.86e-05
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWER--RSHIGG 37
Cdd:COG3573     9 IVVGAGLAGLVAAAELADAGRRVLLLDQepEANLGG 44
PLN02976 PLN02976
amine oxidase
 4-40 1.99e-05

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 41.39  E-value: 1.99e-05
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 1941156864    4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMY 40
Cdd:PLN02976   697 IVVGAGPAGLTAARHLQRQGFSVTVLEARSRIGGRVY 733
FAD_oxidored pfam12831
FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases ...
 4-39 3.24e-05

FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases and related proteins.


Pssm-ID: 432816 [Multi-domain]  Cd Length: 420  Bit Score: 40.67  E-value: 3.24e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1941156864   4 LVVGAGLSG---AVIArklADNGHKVTIWERRSHIGGNM 39
Cdd:pfam12831   3 VVVGGGPAGvaaAIAA---ARAGAKVLLVERRGFLGGML 38
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 4-38 9.51e-05

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 39.44  E-value: 9.51e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGN 38
Cdd:PRK01747  264 AIIGGGIAGAALALALARRGWQVTLYEADEAPAQG 298
PLN02676 PLN02676
polyamine oxidase
 4-40 1.15e-04

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 39.31  E-value: 1.15e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHK-VTIWERRSHIGGNMY 40
Cdd:PLN02676   30 IIVGAGMSGISAAKTLSEAGIEdILILEATDRIGGRMR 67
PLN02529 PLN02529
lysine-specific histone demethylase 1
 4-43 1.43e-04

lysine-specific histone demethylase 1


Pssm-ID: 178144 [Multi-domain]  Cd Length: 738  Bit Score: 39.10  E-value: 1.43e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYK 43
Cdd:PLN02529  164 IIVGAGLAGLAAARQLLSFGFKVVVLEGRNRPGGRVYTQK 203
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 5-37 1.61e-04

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 38.69  E-value: 1.61e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRSHIGG 37
Cdd:PLN02172   15 VIGAGAAGLVAARELRREGHTVVVFEREKQVGG 47
NAD_Gly3P_dh_N pfam01210
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent ...
 5-32 1.72e-04

NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the N-terminal NAD-binding domain.


Pssm-ID: 395967 [Multi-domain]  Cd Length: 158  Bit Score: 37.94  E-value: 1.72e-04
                          10        20
                  ....*....|....*....|....*...
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERR 32
Cdd:pfam01210   4 VLGAGSWGTALAKVLADNGHEVRLWGRD 31
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
 4-37 1.95e-04

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 38.82  E-value: 1.95e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGG 37
Cdd:PLN02328  242 VVVGAGLAGLVAARQLLSMGFKVVVLEGRARPGG 275
GpsA COG0240
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 5-32 2.40e-04

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440010 [Multi-domain]  Cd Length: 327  Bit Score: 38.09  E-value: 2.40e-04
                          10        20
                  ....*....|....*....|....*...
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERR 32
Cdd:COG0240     5 VLGAGSWGTALAKVLARNGHEVTLWGRD 32
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
8-36 2.51e-04

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 38.02  E-value: 2.51e-04
                          10        20
                  ....*....|....*....|....*....
gi 1941156864   8 AGLSGAVIARKLADNGHKVTIWERRSHIG 36
Cdd:COG0644     1 AGPAGSAAARRLARAGLSVLLLEKGSFPG 29
gpsA PRK00094
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
5-32 3.20e-04

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;


Pssm-ID: 234629 [Multi-domain]  Cd Length: 325  Bit Score: 37.74  E-value: 3.20e-04
                          10        20
                  ....*....|....*....|....*...
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERR 32
Cdd:PRK00094    6 VLGAGSWGTALAIVLARNGHDVTLWARD 33
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 5-37 3.37e-04

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 37.96  E-value: 3.37e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTI--WERRSHIGG 37
Cdd:PRK12834    9 VVGAGLAGLVAAAELADAGKRVLLldQENEANLGG 43
PRK13984 PRK13984
putative oxidoreductase; Provisional
 5-84 6.21e-04

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 37.05  E-value: 6.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMydykdEYGINVHKYgPHTFHTNDKNYMSSCfsmrnGNRMHCN--V 82
Cdd:PRK13984  288 IVGSGPAGLSAAYFLATMGYEVTVYESLSKPGGVM-----RYGIPSYRL-PDEALDKDIAFIEAL-----GVKIHLNtrV 356


                  ..
gi 1941156864  83 GH 84
Cdd:PRK13984  357 GK 358
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
1-64 6.27e-04

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 37.05  E-value: 6.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1941156864   1 MEYLVVGAGLSGAVIARKLA-DNGHKVTIWERRSHIG-----------------------------GN--MYDYKDEYGI 48
Cdd:COG0579     5 YDVVIIGAGIVGLALARELSrYEDLKVLVLEKEDDVAqessgnnsgvihaglyytpgslkarlcveGNelFYELCRELGI 84

                          90
                  ....*....|....*.
gi 1941156864  49 NVHKYGPHTFHTNDKN 64
Cdd:COG0579    85 PFKRCGKLVVATGEEE 100
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 4-39 6.50e-04

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 35.26  E-value: 6.50e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 1941156864  4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNM 39
Cdd:pfam00070  3 VVVGGGYIGLELAGALARLGSKVTVVERRDRLLPGF 38
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 1-28 7.92e-04

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 36.58  E-value: 7.92e-04
                          10        20
                  ....*....|....*....|....*...
gi 1941156864   1 MEYLVVGAGLSGAVIARKLADNGHKVTI 28
Cdd:COG0569    96 MHVIIIGAGRVGRSLARELEEEGHDVVV 123
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 5-48 8.18e-04

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 36.63  E-value: 8.18e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYdykdeYGI 48
Cdd:PRK12814  198 IIGAGPAGLTAAYYLLRKGHDVTIFDANEQAGGMMR-----YGI 236
PRK14619 PRK14619
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
 5-33 1.05e-03

NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional


Pssm-ID: 237771 [Multi-domain]  Cd Length: 308  Bit Score: 36.50  E-value: 1.05e-03
                          10        20
                  ....*....|....*....|....*....
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRS 33
Cdd:PRK14619    9 ILGAGAWGSTLAGLASANGHRVRVWSRRS 37
PRK07588 PRK07588
FAD-binding domain;
1-42 1.37e-03

FAD-binding domain;


Pssm-ID: 169028 [Multi-domain]  Cd Length: 391  Bit Score: 36.25  E-value: 1.37e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1941156864   1 MEYLVVGAGLSGAVIARKLADNGHKVTIWERRSHI--GGNMYDY 42
Cdd:PRK07588    1 MKVAISGAGIAGPTLAYWLRRYGHEPTLIERAPELrtGGYMVDF 44
PRK05335 PRK05335
tRNA (uracil-5-)-methyltransferase Gid; Reviewed
 5-34 1.40e-03

tRNA (uracil-5-)-methyltransferase Gid; Reviewed


Pssm-ID: 235416  Cd Length: 436  Bit Score: 35.89  E-value: 1.40e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRSH 34
Cdd:PRK05335    7 VIGAGLAGSEAAWQLAKRGVPVELYEMRPV 36
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 3-31 1.79e-03

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 35.96  E-value: 1.79e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1941156864   3 YLVVGAGLSGAVIARKLA-DNGHKVTIWER 31
Cdd:COG2303     7 YVIVGAGSAGCVLANRLSeDAGLRVLLLEA 36
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 4-38 1.91e-03

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 35.58  E-value: 1.91e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGN 38
Cdd:COG1053     7 VVVGSGGAGLRAALEAAEAGLKVLVLEKVPPRGGH 41
PRK06370 PRK06370
FAD-containing oxidoreductase;
5-37 2.23e-03

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 35.56  E-value: 2.23e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRsHIGG 37
Cdd:PRK06370   10 VIGAGQAGPPLAARAAGLGMKVALIERG-LLGG 41
ApbA pfam02558
Ketopantoate reductase PanE/ApbA; This is a family of 2-dehydropantoate 2-reductases also ...
 3-34 2.56e-03

Ketopantoate reductase PanE/ApbA; This is a family of 2-dehydropantoate 2-reductases also known as ketopantoate reductases, EC:1.1.1.169. The reaction catalyzed by this enzyme is: (R)-pantoate + NADP(+) <=> 2-dehydropantoate + NADPH. AbpA catalyzes the NADPH reduction of ketopantoic acid to pantoic acid in the alternative pyrimidine biosynthetic (APB) pathway. ApbA and PanE are allelic. ApbA, the ketopantoate reductase enzyme is required for the synthesis of thiamine via the APB biosynthetic pathway.


Pssm-ID: 426831 [Multi-domain]  Cd Length: 147  Bit Score: 34.90  E-value: 2.56e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1941156864   3 YLVVGAGLSGAVIARKLADNGHKVTIWERRSH 34
Cdd:pfam02558   1 IAILGAGAIGSLLGARLAKAGHDVTLILRGAE 32
MmsB COG2084
3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport ...
 5-32 2.90e-03

3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport and metabolism];


Pssm-ID: 441687 [Multi-domain]  Cd Length: 285  Bit Score: 35.09  E-value: 2.90e-03
                          10        20
                  ....*....|....*....|....*...
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERR 32
Cdd:COG2084     6 FIGLGAMGAPMARNLLKAGHEVTVWNRT 33
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
4-39 4.01e-03

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 34.89  E-value: 4.01e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNM 39
Cdd:PRK04965  145 LVVGGGLIGTELAMDLCRAGKAVTLVDNAASLLASL 180
TrmFO COG1206
Folate-dependent tRNA-U54 methylase TrmFO/GidA [Translation, ribosomal structure and ...
 5-34 4.65e-03

Folate-dependent tRNA-U54 methylase TrmFO/GidA [Translation, ribosomal structure and biogenesis]; Folate-dependent tRNA-U54 methylase TrmFO/GidA is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440819  Cd Length: 436  Bit Score: 34.65  E-value: 4.65e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1941156864   5 VVGAGLSGAVIARKLADNGHKVTIWERRSH 34
Cdd:COG1206     6 VIGGGLAGSEAAWQLAERGVPVRLYEMRPV 35
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
4-42 5.87e-03

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 34.50  E-value: 5.87e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIggnmYDY 42
Cdd:PRK06183   14 VIVGAGPVGLTLANLLGQYGVRVLVLERWPTL----YDL 48
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
2-43 7.14e-03

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 34.12  E-value: 7.14e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1941156864   2 EYLVVGAGLSGAVIARKLADNGHKVTIWERRSHIGGNMYDYK 43
Cdd:pfam13738 157 KVVVIGGYNSAVDAALELVRKGARVTVLYRGSEWEDRDSDPS 198
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
4-62 7.64e-03

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 33.86  E-value: 7.64e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGgnmydykdEYGINVhKYGPHTFHTND 62
Cdd:PRK08163    8 LIVGGGIGGLAAALALARQGIKVKLLEQAAEIG--------EIGAGI-QLGPNAFSALD 57
PRK07208 PRK07208
hypothetical protein; Provisional
 4-37 9.91e-03

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 33.71  E-value: 9.91e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1941156864   4 LVVGAGLSGAVIARKLADNGHKVTIWERRSHIGG 37
Cdd:PRK07208    8 VIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGG 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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