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Conserved domains on  [gi|1940128874|dbj|BCD55764|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Circus spilonotus spilonotus]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 2.31e-48

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 154.52  E-value: 2.31e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874   1 MAYFVVFLGVGFVLGGLAASSNPSPYYGVVGLVLGSVVGCGWLVSLGVPFVALVLFMVYLGGMLVVFVYSVCMAADPFPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874  81 AWGDWRVVGYGV--GMVLVLVVGVVVGGVECWEVGVITVDSGGTFVERLDFSGVAMFYSCGGGMFLVAGWGLLLTLFVVL 158
Cdd:MTH00115   81 AWGDWGVVGYVVgfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 1940128874 159 ELVRGLSCGAIRAV 172
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 2.31e-48

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 154.52  E-value: 2.31e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874   1 MAYFVVFLGVGFVLGGLAASSNPSPYYGVVGLVLGSVVGCGWLVSLGVPFVALVLFMVYLGGMLVVFVYSVCMAADPFPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874  81 AWGDWRVVGYGV--GMVLVLVVGVVVGGVECWEVGVITVDSGGTFVERLDFSGVAMFYSCGGGMFLVAGWGLLLTLFVVL 158
Cdd:MTH00115   81 AWGDWGVVGYVVgfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 1940128874 159 ELVRGLSCGAIRAV 172
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 3.12e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 47.11  E-value: 3.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874  17 LAASSNPSPYYGVVGLVLGSVVGCGWLVSLGVPFVALVLFMVYLGGMLVVFVYSVCM-AADPFPEAWGDWRVVGYGVGMV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1940128874  96 LVLVVGVVVGGVECWEVGVITVDSGGTFVERLdfsGVAMFYScGGGMFLVAGWGLLLTLFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAI---GELLFTD-YLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 2.31e-48

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 154.52  E-value: 2.31e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874   1 MAYFVVFLGVGFVLGGLAASSNPSPYYGVVGLVLGSVVGCGWLVSLGVPFVALVLFMVYLGGMLVVFVYSVCMAADPFPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874  81 AWGDWRVVGYGV--GMVLVLVVGVVVGGVECWEVGVITVDSGGTFVERLDFSGVAMFYSCGGGMFLVAGWGLLLTLFVVL 158
Cdd:MTH00115   81 AWGDWGVVGYVVgfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 1940128874 159 ELVRGLSCGAIRAV 172
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 8.48e-47

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 150.29  E-value: 8.48e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874   1 MAYFVVFLGVGFVLGGLAASSNPSPYYGVVGLVLGSVVGCGWLVSLGVPFVALVLFMVYLGGMLVVFVYSVCMAADPFPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874  81 AWGDWRVVGYGVGMVLVLVVGVVVGGVECWEVGVITVDSGGTF-VERLDFSGVAMFYSCGGGMFLVAGWGLLLTLFVVLE 159
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFsVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1940128874 160 LVRGLSCGAIRAV 172
Cdd:MTH00138  161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 2.00e-41

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 136.90  E-value: 2.00e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874   1 MAYFVVFLGVGFVLGGLAASSNPSPYYGVVGLVLGSVVGCGWLVSLGVPFVALVLFMVYLGGMLVVFVYSVCMAADPFPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874  81 AWGDWRVVGYGVGMVLVLVVGVVVGGVECWEVGVITVDSGGTFVERLDFSGVAMFYSCGGGMFLVAGWGLLLTLFVVLEL 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                         170
                  ....*....|..
gi 1940128874 161 VRGLSCGAIRAV 172
Cdd:MTH00065  161 TRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-163 5.57e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 92.17  E-value: 5.57e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874   1 MAYFVVFLGVGFVLGGLAASSNPSPYYGVVGLVLGSVVGCGWLVSLGVPFVALVLFMVYLGGMLVVFVYSVCMAADPFPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874  81 AWGDWRVVGYGVGMVLVLVVGVVVGGVECWEVGVITV----------DSGGTFVERLDFSGVAMFYSCGGGMFLVAGWGL 150
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNfnglgdwviyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                         170
                  ....*....|...
gi 1940128874 151 LLTLFVVLELVRG 163
Cdd:MTH00109  162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 1.07e-20

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 83.50  E-value: 1.07e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874   1 MAYFVVFLGVGFVLGGLAASSNPSPYYGVVGLVLGSVVGCGWLVSLGVPFVALVLFMVYLGGMLVVFVYSVCMAADPFPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874  81 AWGDWRVVGYGVGMVLVLVVGVVVGGVECWEVGVITVDSGGTfverLDFSGVAMFYSCGGGMFLVAGWGLLLTLFVVLEL 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANN----LDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLEL 156

                         170
                  ....*....|..
gi 1940128874 161 VRGLSCGAIRAV 172
Cdd:MTH00214  157 VRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 24-171 3.60e-11

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 58.38  E-value: 3.60e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874  24 SPYYGVVGLVLGSVVGCGWLVSLGVPFVALVLFMVYLGGMLVVFVYSVCMAADPFPEAwGDWRVVGYGVGMVLVLVVGVV 103
Cdd:MTH00045   22 SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSV-SNLGEVLVLSLLLSLWVFISF 100

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1940128874 104 VGGVECWEvgvitvdSGGTFVERLDFSGVAMFYSCGGGMFLVAGWGLLLTLFVVLELVRGLSCGAIRA 171
Cdd:MTH00045  101 DNFLELSN-------NNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 3.12e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 47.11  E-value: 3.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940128874  17 LAASSNPSPYYGVVGLVLGSVVGCGWLVSLGVPFVALVLFMVYLGGMLVVFVYSVCM-AADPFPEAWGDWRVVGYGVGMV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1940128874  96 LVLVVGVVVGGVECWEVGVITVDSGGTFVERLdfsGVAMFYScGGGMFLVAGWGLLLTLFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAI---GELLFTD-YLLPFELASVLLLVALVGAIVL 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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