NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1935448368|ref|YP_009947916|]
View 

NADH dehydrogenase subunit 4L (mitochondrion) [Coenomyia ferruginea]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 3.60e-23

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 84.82  E-value: 3.60e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368  4 IMVWGLPIFLFLVGLIVFVSNRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNYEAFFSMFFLTFSVCEGALGLSILVSLIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1935448368 84 THGNDYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 3.60e-23

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 84.82  E-value: 3.60e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368  4 IMVWGLPIFLFLVGLIVFVSNRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNYEAFFSMFFLTFSVCEGALGLSILVSLIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1935448368 84 THGNDYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
11-98 1.57e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 52.57  E-value: 1.57e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368 11 IFLFLVGLIVFVSnRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNY--EAFFSMFFLTFSVCEGALGLSILVSLIRTHGND 88
Cdd:pfam00420  7 GLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADplPQALILTAIVIAAAEAAVGLALLVRIYRTHGTD 85

                         90
                 ....*....|
gi 1935448368 89 YFQSFNVLQC 98
Cdd:pfam00420 86 DVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 3.60e-23

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 84.82  E-value: 3.60e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368  4 IMVWGLPIFLFLVGLIVFVSNRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNYEAFFSMFFLTFSVCEGALGLSILVSLIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1935448368 84 THGNDYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 2-98 1.22e-15

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 65.77  E-value: 1.22e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368  2 LMIMVWGLPIFLFLVGLIVFVSNRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNYEAFFSMFFLTFSVCEGALGLSILVSL 81
Cdd:MTH00188   1 MFFSMILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSL 80

                         90
                 ....*....|....*..
gi 1935448368 82 IRTHGNDYFQSFNVLQC 98
Cdd:MTH00188  81 IRSHGSDYVSSLNLIKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 14-98 1.75e-15

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 65.64  E-value: 1.75e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368 14 FLVGLIVFVSNRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNYEAFFSM--FFLTFSVCEGALGLSILVSLIRTHGNDYFQ 91
Cdd:MTH00125  12 FMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALLVATTRTHGSDHLK 91


                 ....*..
gi 1935448368 92 SFNVLQC 98
Cdd:MTH00125  92 NLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 14-98 5.94e-15

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 64.22  E-value: 5.94e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368 14 FLVGLIVFVSNRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNYEAFFS--MFFLTFSVCEGALGLSILVSLIRTHGNDYFQ 91
Cdd:MTH00126  12 FILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAapMLLLAFSACEASAGLALLVATARTHGTDRLQ 91


                 ....*..
gi 1935448368 92 SFNVLQC 98
Cdd:MTH00126  92 NLNLLQC 98
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 3-98 1.60e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 62.94  E-value: 1.60e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368  3 MIMVWGLPIFLFLVGLIVFVSNRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNYEAFFSMFFLTFSVCEGALGLSILVSLI 82
Cdd:MTH00149   2 MFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLI 81

                         90
                 ....*....|....*.
gi 1935448368 83 RTHGNDYFQSFNVLQC 98
Cdd:MTH00149  82 RLHGNDYVSSLSSLKF 97
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 14-98 2.06e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 62.70  E-value: 2.06e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368 14 FLVGLIVFVSNRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNYEAFFS--MFFLTFSVCEGALGLSILVSLIRTHGNDYFQ 91
Cdd:MTH00067  12 FLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSlpMFMLTFSACEASTGLALMVATTRTHGTDHLK 91


                 ....*..
gi 1935448368 92 SFNVLQC 98
Cdd:MTH00067  92 NLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
11-98 1.57e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 52.57  E-value: 1.57e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368 11 IFLFLVGLIVFVSnRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNY--EAFFSMFFLTFSVCEGALGLSILVSLIRTHGND 88
Cdd:pfam00420  7 GLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADplPQALILTAIVIAAAEAAVGLALLVRIYRTHGTD 85

                         90
                 ....*....|
gi 1935448368 89 YFQSFNVLQC 98
Cdd:pfam00420 86 DVDSLNLLKG 95
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 11-97 1.27e-09

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 50.30  E-value: 1.27e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368 11 IFLFLVGLIVFVSNRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNYEAF--FSMFFLTFSVCEGALGLSILVSLIRTHGND 88
Cdd:MTH00043   9 LSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVLLSRNHNSD 88


                 ....*....
gi 1935448368 89 YFQSFNVLQ 97
Cdd:MTH00043  89 LVASLNLLQ 97
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 11-96 4.18e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 49.17  E-value: 4.18e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368 11 IFLFLVGLIVFVSNRKHLLSMLLSLEFIVLSLF--LMLFIFLCLFNYEAFFSMFFLTFSVCEGALGLSILVSLIRTHGND 88
Cdd:MTH00181   6 ISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFllLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRTHGSD 85


                 ....*...
gi 1935448368 89 YFQSFNVL 96
Cdd:MTH00181  86 HLLKFNLL 93
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 14-98 5.12e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 48.77  E-value: 5.12e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368 14 FLVGLIVFVSNRKHLLSMLLSLEFIVLSLFLMLFIFLCLFNYEAFFSM--FFLTFSVCEGALGLSILVSLIRTHGNDYFQ 91
Cdd:MTH00107  12 FTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMpiILLVFAACEAAVGLALLVMVSNTYGTDYVQ 91


                 ....*..
gi 1935448368 92 SFNVLQC 98
Cdd:MTH00107  92 NLNLLQC 98
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 11-98 4.54e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 43.97  E-value: 4.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368 11 IFLFLVGLIVFVSNRKHLLSMLLSLEFIVLSLFLMLFIFLCLFN-YEAFFSMFFLTFSVCEGALGLSILVSLIRTHGNDY 89
Cdd:MTH00013   9 SISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFANqVNGMLAIVLLTFGACEASLGLSLLVLMTRSYGNDM 88


                 ....*....
gi 1935448368 90 FQSFNVLQC 98
Cdd:MTH00013  89 LKSLTSNKC 97
ND4L MTH00180
NADH dehydrogenase subunit 4L; Provisional
 11-97 2.98e-03

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177231  Cd Length: 99  Bit Score: 33.85  E-value: 2.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368 11 IFLFLVGLIVFVSNRKHLLSMLLSLEFIVLSL-FLMLFIFLCLFNYEA-FFSMFFLTFSVCEGALGLSILVSLIRTHGND 88
Cdd:MTH00180  10 IILFILGVLGIVLNRSNLIIMLMSIELMLLAIsLLFLINSVAIDNLIGqIFTIMILTVAAAESAIGLAILVAYYRIRGTI 89


                 ....*....
gi 1935448368 89 YFQSFNVLQ 97
Cdd:MTH00180  90 AVKSLNLLR 98
ND4L MTH00001
NADH dehydrogenase subunit 4L; Provisional
 9-97 3.79e-03

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177099  Cd Length: 99  Bit Score: 33.88  E-value: 3.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935448368  9 LPIFLFLVGLIVFVSNRKHLLSMLLSLEFIVLSLFlMLFIFLCLFNY---EAFFSMFFLTFSVCEGALGLSILVSLIRTH 85
Cdd:MTH00001   8 LVVILFLLGIWGIILNRGHFIIMLVSIELVLLSTF-FLFLINSIEIDlliEQIFTIMGLTIAAAESAIGLAIMVAYYRIR 86

                         90
                 ....*....|..
gi 1935448368 86 GNDYFQSFNVLQ 97
Cdd:MTH00001  87 GTISLKSLNSLR 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH