|
Name |
Accession |
Description |
Interval |
E-value |
| ubiE |
PRK00216 |
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ... |
26-264 |
2.68e-149 |
|
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;
Pssm-ID: 234689 [Multi-domain] Cd Length: 239 Bit Score: 416.48 E-value: 2.68e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 26 FKQVEKSQKASMVANVFDSVAAKYDVMNDLMSLGVHRLWKRYTIDCSGVRAGHKVLDIAGGTGDLTAKFSRMVGPTGSVT 105
Cdd:PRK00216 1 FMTVAEEEKQEKVAEMFDSIAPKYDLMNDLLSFGLHRVWRRKTIKWLGVRPGDKVLDLACGTGDLAIALAKAVGKTGEVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 106 LADINLSMLKVGRDKLRDKGLVSNIDYVQADAESLPFPDNTFDVVTMAFGLRNVTEKQNALNSIYRVLKPGGRLLVLEFS 185
Cdd:PRK00216 81 GLDFSEGMLAVGREKLRDLGLSGNVEFVQGDAEALPFPDNSFDAVTIAFGLRNVPDIDKALREMYRVLKPGGRLVILEFS 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1935375888 186 KPASEHLSKLYDVYSFHILPRMGQVVANDEESYRYLAESIRMHPDQETLKGMFEQAGFEQCDYSNLTGGIVALHRGYKF 264
Cdd:PRK00216 161 KPTNPPLKKAYDFYLFKVLPLIGKLISKNAEAYSYLAESIRAFPDQEELAAMLEEAGFERVRYRNLTGGIVALHVGYKP 239
|
|
| Ubie_methyltran |
pfam01209 |
ubiE/COQ5 methyltransferase family; |
38-263 |
1.03e-118 |
|
ubiE/COQ5 methyltransferase family;
Pssm-ID: 395966 [Multi-domain] Cd Length: 228 Bit Score: 338.64 E-value: 1.03e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 38 VANVFDSVAAKYDVMNDLMSLGVHRLWKRYTIDCSGVRAGHKVLDIAGGTGDLTAKFSRMVGPTGSVTLADINLSMLKVG 117
Cdd:pfam01209 4 VGDVFSSVASKYDLMNDVISFGIHRLWKDFTMKCMGVKRGNKFLDVAGGTGDWTFGLSDSAGSSGKVVGLDINENMLKEG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 118 RDKLRDKGlVSNIDYVQADAESLPFPDNTFDVVTMAFGLRNVTEKQNALNSIYRVLKPGGRLLVLEFSKPASEHLSKLYD 197
Cdd:pfam01209 84 EKKAKEEG-KYNIEFLQGNAEELPFEDDSFDIVTISFGLRNFPDYLKVLKEAFRVLKPGGRVVCLEFSKPENPLLSQAYE 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1935375888 198 VYSFHILPRMGQVVANDEESYRYLAESIRMHPDQETLKGMFEQAGFEQCDYSNLTGGIVALHRGYK 263
Cdd:pfam01209 163 LYFKYVMPFMGKMFAKSYKSYQYLQESIRDFPDQKTLASMFEKAGFKSVGYESLTGGIAAIHWGIK 228
|
|
| MenG_MenH_UbiE |
TIGR01934 |
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ... |
38-263 |
1.08e-116 |
|
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 273884 [Multi-domain] Cd Length: 223 Bit Score: 333.46 E-value: 1.08e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 38 VANVFDSVAAKYDVMNDLMSLGVHRLWKRYTIDCSGVRAGHKVLDIAGGTGDLTAKFSRMVGPTGSVTLADINLSMLKVG 117
Cdd:TIGR01934 1 VQEMFDRIAPKYDLLNDLLSFGLHRLWRRRAVKLIGVFKGQKVLDVACGTGDLAIELAKSAPDRGKVTGVDFSSEMLEVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 118 RDKLRDKglvSNIDYVQADAESLPFPDNTFDVVTMAFGLRNVTEKQNALNSIYRVLKPGGRLLVLEFSKPASEHLSKLYD 197
Cdd:TIGR01934 81 KKKSELP---LNIEFIQADAEALPFEDNSFDAVTIAFGLRNVTDIQKALREMYRVLKPGGRLVILEFSKPANALLKKFYK 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1935375888 198 VYSFHILPRMGQVVANDEESYRYLAESIRMHPDQETLKGMFEQAGFEQCDYSNLTGGIVALHRGYK 263
Cdd:TIGR01934 158 FYLKNVLPSIGGLISKNAEAYTYLPESIRAFPSQEELAAMLKEAGFEEVRYRSLTFGVAAIHVGKK 223
|
|
| PLN02233 |
PLN02233 |
ubiquinone biosynthesis methyltransferase |
41-256 |
4.65e-45 |
|
ubiquinone biosynthesis methyltransferase
Pssm-ID: 177877 [Multi-domain] Cd Length: 261 Bit Score: 152.35 E-value: 4.65e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 41 VFDSVAAKYDVMNDLMSLGVHRLWKRYTIDCSGVRAGHKVLDIAGGTGDLTAKFSRMVGPTGSVTLADINLSMLKVG--R 118
Cdd:PLN02233 38 LFNRIAPVYDNLNDLLSLGQHRIWKRMAVSWSGAKMGDRVLDLCCGSGDLAFLLSEKVGSDGKVMGLDFSSEQLAVAasR 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 119 DKLRDKGLVSNIDYVQADAESLPFPDNTFDVVTMAFGLRNVTEKQNALNSIYRVLKPGGRLLVLEFSKPASEHLSKLYDV 198
Cdd:PLN02233 118 QELKAKSCYKNIEWIEGDATDLPFDDCYFDAITMGYGLRNVVDRLKAMQEMYRVLKPGSRVSILDFNKSTQPFTTSMQEW 197
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1935375888 199 YSFHILPRMGQVVANDEEsYRYLAESIRMHPDQETLKGMFEQAGFEQCDYSNLTGGIV 256
Cdd:PLN02233 198 MIDNVVVPVATGYGLAKE-YEYLKSSINEYLTGEELEKLALEAGFSSAKHYEISGGLM 254
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
42-195 |
3.17e-44 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 146.29 E-value: 3.17e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 42 FDSVAAKYDVmndlmslgvhrlwKRYTIDCSGVRAGHKVLDIAGGTGDLTAKFSRMvgpTGSVTLADINLSMLKVGRDKL 121
Cdd:COG2226 1 FDRVAARYDG-------------REALLAALGLRPGARVLDLGCGTGRLALALAER---GARVTGVDISPEMLELARERA 64
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1935375888 122 RDKGLvsNIDYVQADAESLPFPDNTFDVVTMAFGLRNVTEKQNALNSIYRVLKPGGRLLVLEFSKPASEHLSKL 195
Cdd:COG2226 65 AEAGL--NVEFVVGDAEDLPFPDGSFDLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFSPPDLAELEEL 136
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
80-177 |
4.23e-30 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 108.42 E-value: 4.23e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 80 VLDIAGGTGDLTAKFSRMVGptGSVTLADINLSMLKVGRDKLRDKGLvsNIDYVQADAESLPFPDNTFDVVTMAFGLRNV 159
Cdd:pfam13649 1 VLDLGCGTGRLTLALARRGG--ARVTGVDLSPEMLERARERAAEAGL--NVEFVQGDAEDLPFPDGSFDLVVSSGVLHHL 76
|
90 100
....*....|....*....|
gi 1935375888 160 TEKQ--NALNSIYRVLKPGG 177
Cdd:pfam13649 77 PDPDleAALREIARVLKPGG 96
|
|
| PRK08317 |
PRK08317 |
hypothetical protein; Provisional |
74-252 |
1.30e-25 |
|
hypothetical protein; Provisional
Pssm-ID: 181382 [Multi-domain] Cd Length: 241 Bit Score: 100.78 E-value: 1.30e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 74 VRAGHKVLDIAGGTGDLTAKFSRMVGPTGSVTLADINLSMLKVGRDklRDKGLVSNIDYVQADAESLPFPDNTFDVVTMA 153
Cdd:PRK08317 17 VQPGDRVLDVGCGPGNDARELARRVGPEGRVVGIDRSEAMLALAKE--RAAGLGPNVEFVRGDADGLPFPDGSFDAVRSD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 154 FGLRNVTEKQNALNSIYRVLKPGGRLLVLE-------FSKPASEHLSKLYDVYSFHIL-PRMGqvvandeesyRYLAesi 225
Cdd:PRK08317 95 RVLQHLEDPARALAEIARVLRPGGRVVVLDtdwdtlvWHSGDRALMRKILNFWSDHFAdPWLG----------RRLP--- 161
|
170 180
....*....|....*....|....*....
gi 1935375888 226 rmhpdqetlkGMFEQAGF--EQCDYSNLT 252
Cdd:PRK08317 162 ----------GLFREAGLtdIEVEPYTLI 180
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
81-181 |
1.12e-23 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 91.57 E-value: 1.12e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 81 LDIAGGTGDLTAKFSRMVGptgSVTLADINLSMLKVGRDKLRDKGLvsniDYVQADAESLPFPDNTFDVVTMAFGLRNVT 160
Cdd:pfam08241 1 LDVGCGTGLLTELLARLGA---RVTGVDISPEMLELAREKAPREGL----TFVVGDAEDLPFPDNSFDLVLSSEVLHHVE 73
|
90 100
....*....|....*....|.
gi 1935375888 161 EKQNALNSIYRVLKPGGRLLV 181
Cdd:pfam08241 74 DPERALREIARVLKPGGILII 94
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
74-181 |
3.87e-22 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 88.54 E-value: 3.87e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 74 VRAGHKVLDIAGGTGDLTAKFSRMvgptG-SVTLADINLSMLKVGRDKLRDkglvSNIDYVQADAESLPFPDNTFDVVTM 152
Cdd:COG2227 22 LPAGGRVLDVGCGTGRLALALARR----GaDVTGVDISPEALEIARERAAE----LNVDFVQGDLEDLPLEDGSFDLVIC 93
|
90 100
....*....|....*....|....*....
gi 1935375888 153 AFGLRNVTEKQNALNSIYRVLKPGGRLLV 181
Cdd:COG2227 94 SEVLEHLPDPAALLRELARLLKPGGLLLL 122
|
|
| PLN02232 |
PLN02232 |
ubiquinone biosynthesis methyltransferase |
118-257 |
1.22e-18 |
|
ubiquinone biosynthesis methyltransferase
Pssm-ID: 165876 Cd Length: 160 Bit Score: 80.50 E-value: 1.22e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 118 RDKLRDKGLVSNIDYVQADAESLPFPDNTFDVVTMAFGLRNVTEKQNALNSIYRVLKPGGRLLVLEFSKpASEHLSKLYD 197
Cdd:PLN02232 16 RQSLKARSCYKCIEWIEGDAIDLPFDDCEFDAVTMGYGLRNVVDRLRAMKEMYRVLKPGSRVSILDFNK-SNQSVTTFMQ 94
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 198 VYSFHILPRMGQVVANDEESYRYLAESIRMHPDQETLKGMFEQAGFEQCDYSNLTGGIVA 257
Cdd:PLN02232 95 GWMIDNVVVPVATVYDLAKEYEYLKYSINGYLTGEELETLALEAGFSSACHYEISGGFMG 154
|
|
| BioC |
TIGR02072 |
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ... |
42-205 |
4.01e-18 |
|
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]
Pssm-ID: 273953 [Multi-domain] Cd Length: 240 Bit Score: 80.79 E-value: 4.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 42 FDSVAAKYDVMNDLMSLGVHRLWKRytIDCSGVRAGHKVLDIAGGTGDLTAKFSRMvGPTGSVTLADINLSMLKVGRDKL 121
Cdd:TIGR02072 2 FNKAAKTYDRHAKIQREMAKRLLAL--LKEKGIFIPASVLDIGCGTGYLTRALLKR-FPQAEFIALDISAGMLAQAKTKL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 122 RdkglvSNIDYVQADAESLPFPDNTFDVVTMAFGLRNVTEKQNALNSIYRVLKPGGrllVLEFSKPASEHLSKLYDVYSF 201
Cdd:TIGR02072 79 S-----ENVQFICGDAEKLPLEDSSFDLIVSNLALQWCDDLSQALSELARVLKPGG---LLAFSTFGPGTLHELRQSFGQ 150
|
....
gi 1935375888 202 HILP 205
Cdd:TIGR02072 151 HGLR 154
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
75-242 |
5.45e-18 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 78.23 E-value: 5.45e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 75 RAGHKVLDIAGGTGDLTAKFSRMVGPTGSVTLADINLSMLKVGRDKLRDKGLvSNIDYVQADAESLP--FPDNTFDVVTM 152
Cdd:pfam13847 2 DKGMRVLDLGCGTGHLSFELAEELGPNAEVVGIDISEEAIEKARENAQKLGF-DNVEFEQGDIEELPelLEDDKFDVVIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 153 AFGLRNVTEKQNALNSIYRVLKPGGRLLVLEFSkpasehlsklydvysfhilpRMGQVVANDEESYRYLAESIRMHPDQE 232
Cdd:pfam13847 81 NCVLNHIPDPDKVLQEILRVLKPGGRLIISDPD--------------------SLAELPAHVKEDSTYYAGCVGGAILKK 140
|
170
....*....|
gi 1935375888 233 TLKGMFEQAG 242
Cdd:pfam13847 141 KLYELLEEAG 150
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
76-181 |
5.33e-17 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 74.09 E-value: 5.33e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 76 AGHKVLDIAGGTGDLTAKFSRMVgPTGSVTLADINLSMLKVGRDKLrdkglvSNIDYVQADAESLPfPDNTFDVVTMAFG 155
Cdd:COG4106 1 PPRRVLDLGCGTGRLTALLAERF-PGARVTGVDLSPEMLARARARL------PNVRFVVADLRDLD-PPEPFDLVVSNAA 72
|
90 100
....*....|....*....|....*.
gi 1935375888 156 LRNVTEKQNALNSIYRVLKPGGRLLV 181
Cdd:COG4106 73 LHWLPDHAALLARLAAALAPGGVLAV 98
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
38-180 |
2.68e-15 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 71.95 E-value: 2.68e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 38 VANVFDSVAAKYDvmNDLMSLGVHRLWKRY---TIDCSGVRAGHKVLDIAGGTGDLTAKFSRMVGptgSVTLADINLSML 114
Cdd:COG4976 7 VEALFDQYADSYD--AALVEDLGYEAPALLaeeLLARLPPGPFGRVLDLGCGTGLLGEALRPRGY---RLTGVDLSEEML 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1935375888 115 kvgrDKLRDKGLvsNIDYVQADAESLPFPDNTFDVVTMAFGLRNVTEKQNALNSIYRVLKPGGRLL 180
Cdd:COG4976 82 ----AKAREKGV--YDRLLVADLADLAEPDGRFDLIVAADVLTYLGDLAAVFAGVARALKPGGLFI 141
|
|
| Methyltransf_12 |
pfam08242 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
81-179 |
6.13e-15 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 400515 [Multi-domain] Cd Length: 98 Bit Score: 68.55 E-value: 6.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 81 LDIAGGTGDLTAKFSRMVgPTGSVTLADINLSMLKVGRDKLRDKGL--VSNIDYVQADAESLPFPdnTFDVVTMAFGLRN 158
Cdd:pfam08242 1 LEIGCGTGTLLRALLEAL-PGLEYTGLDISPAALEAARERLAALGLlnAVRVELFQLDLGELDPG--SFDVVVASNVLHH 77
|
90 100
....*....|....*....|.
gi 1935375888 159 VTEKQNALNSIYRVLKPGGRL 179
Cdd:pfam08242 78 LADPRAVLRNIRRLLKPGGVL 98
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
79-181 |
9.96e-15 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 68.23 E-value: 9.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 79 KVLDIAGGTGDLTAKFSRmvGPTGSVTLADINLSMLKVGRdKLRDKGLVSNIDYVQADAESLPF-PDNTFDVVTMAFGLR 157
Cdd:cd02440 1 RVLDLGCGTGALALALAS--GPGARVTGVDISPVALELAR-KAAAALLADNVEVLKGDAEELPPeADESFDVIISDPPLH 77
|
90 100
....*....|....*....|....*
gi 1935375888 158 -NVTEKQNALNSIYRVLKPGGRLLV 181
Cdd:cd02440 78 hLVEDLARFLEEARRLLKPGGVLVL 102
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
73-181 |
4.32e-14 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 68.03 E-value: 4.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 73 GVRAGHKVLDIAGGTGDLTAKFSRMVGptGSVTLADINLSMLKVGRDKLRDKGLVSNIDYVQADAESLPfPDNTFDVV-- 150
Cdd:COG2230 48 GLKPGMRVLDIGCGWGGLALYLARRYG--VRVTGVTLSPEQLEYARERAAEAGLADRVEVRLADYRDLP-ADGQFDAIvs 124
|
90 100 110
....*....|....*....|....*....|....
gi 1935375888 151 ---TMAFGLRNVTEkqnALNSIYRVLKPGGRLLV 181
Cdd:COG2230 125 igmFEHVGPENYPA---YFAKVARLLKPGGRLLL 155
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
79-181 |
6.12e-14 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 68.40 E-value: 6.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 79 KVLDIAGGTGDLTAKFSRMVGptGSVTLADINLSMLKVGRDKLRDKGLvSNIDYVQAD-AESLPFPDNTFDVVTmAFGLR 157
Cdd:COG0500 29 RVLDLGCGTGRNLLALAARFG--GRVIGIDLSPEAIALARARAAKAGL-GNVEFLVADlAELDPLPAESFDLVV-AFGVL 104
|
90 100
....*....|....*....|....*..
gi 1935375888 158 NVTEKQN---ALNSIYRVLKPGGRLLV 181
Cdd:COG0500 105 HHLPPEEreaLLRELARALKPGGVLLL 131
|
|
| arsM |
PRK11873 |
arsenite methyltransferase; |
75-245 |
1.81e-13 |
|
arsenite methyltransferase;
Pssm-ID: 237007 [Multi-domain] Cd Length: 272 Bit Score: 68.44 E-value: 1.81e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 75 RAGHKVLDIAGGTG-D--LTAkfsRMVGPTGSVTLADINLSMLKVGRDKLRdKGLVSNIDYVQADAESLPFPDNTFDVVt 151
Cdd:PRK11873 76 KPGETVLDLGSGGGfDcfLAA---RRVGPTGKVIGVDMTPEMLAKARANAR-KAGYTNVEFRLGEIEALPVADNSVDVI- 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 152 mafgLRN-----VTEKQNALNSIYRVLKPGGRLLVlefskpaSEhlsklydvysfhilprmgqVVANDEesyryLAESIR 226
Cdd:PRK11873 151 ----ISNcvinlSPDKERVFKEAFRVLKPGGRFAI-------SD-------------------VVLRGE-----LPEEIR 195
|
170 180 190
....*....|....*....|....*....|
gi 1935375888 227 MHPD-----------QETLKGMFEQAGFEQ 245
Cdd:PRK11873 196 NDAElyagcvagalqEEEYLAMLAEAGFVD 225
|
|
| Gcd14 |
COG2519 |
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ... |
72-197 |
2.53e-13 |
|
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 442009 [Multi-domain] Cd Length: 249 Bit Score: 67.49 E-value: 2.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 72 SGVRAGHKVLDIAGGTGDLTAKFSRMVGPTGSVTLADINLSMLKVGRDKLRDKGLVSNIDYVQADAESlPFPDNTFDVVT 151
Cdd:COG2519 87 LDIFPGARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLERFGLPDNVELKLGDIRE-GIDEGDVDAVF 165
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1935375888 152 MafglrNVTEKQNALNSIYRVLKPGGRLLVLefsKPASEHLSKLYD 197
Cdd:COG2519 166 L-----DMPDPWEALEAVAKALKPGGVLVAY---VPTVNQVSKLVE 203
|
|
| COG4798 |
COG4798 |
Predicted methyltransferase [General function prediction only]; |
73-244 |
1.87e-11 |
|
Predicted methyltransferase [General function prediction only];
Pssm-ID: 443826 Cd Length: 274 Bit Score: 62.63 E-value: 1.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 73 GVRAGHKVLDIAGGTGDLTAKFSRMVGPTGSVTLA-----DINLSMLKVGRDKLR-----DKGLVSNIDYVQADAESLPF 142
Cdd:COG4798 63 GVKPGMTVVEIWPGGGWYTEILAPYLGPKGKVYAAnfdpdSEPPEYAKRSREAFSaklaaDPALYGNVRVTAFAPPDDPI 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 143 -PDNTFDVVTMAfglRNV------TEKQNALNSIYRVLKPGGRLLVLEFSKPASEHLSklydvysfhilprmgqvvanDE 215
Cdd:COG4798 143 aPPGSADLVLTF---RNYhnwyraGDAAAMFAAFFKALKPGGVLGVVDHRAPPGTGLE--------------------AV 199
|
170 180
....*....|....*....|....*....
gi 1935375888 216 ESYRYLaesirmhpDQETLKGMFEQAGFE 244
Cdd:COG4798 200 ATLGYI--------DEAYVIALAEAAGFE 220
|
|
| PRK10258 |
PRK10258 |
biotin biosynthesis protein BioC; Provisional |
38-179 |
1.56e-09 |
|
biotin biosynthesis protein BioC; Provisional
Pssm-ID: 182340 [Multi-domain] Cd Length: 251 Bit Score: 56.69 E-value: 1.56e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 38 VANVFDSVAAKYDVMNDLMSLGVHRLwkrytIDCSGVRAGHKVLDIAGGTGDLtakfSRMVGPTGS-VTLADINLSMLKV 116
Cdd:PRK10258 9 IAAAFGRAAAHYEQHAELQRQSADAL-----LAMLPQRKFTHVLDAGCGPGWM----SRYWRERGSqVTALDLSPPMLAQ 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1935375888 117 GRDKLRDKglvsniDYVQADAESLPFPDNTFDVVTMAFGLRNVTEKQNALNSIYRVLKPGGRL 179
Cdd:PRK10258 80 ARQKDAAD------HYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVV 136
|
|
| Methyltransf_23 |
pfam13489 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
75-244 |
2.35e-09 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 404385 [Multi-domain] Cd Length: 162 Bit Score: 55.13 E-value: 2.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 75 RAGHKVLDIAGGTGDLTAKFSRmVGPTgsVTLADINLSMlkvgrdklrDKGLVSNIDYVQADAESLPFPDNTFDVVTMAF 154
Cdd:pfam13489 21 PSPGRVLDFGCGTGIFLRLLRA-QGFS--VTGVDPSPIA---------IERALLNVRFDQFDEQEAAVPAGKFDVIVARE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 155 GLRNVTEKQNALNSIYRVLKPGGRLLVLEFSKPASEHLSKLYDVYSFHILPRMgqvvandeeSYrylaesirmhPDQETL 234
Cdd:pfam13489 89 VLEHVPDPPALLRQIAALLKPGGLLLLSTPLASDEADRLLLEWPYLRPRNGHI---------SL----------FSARSL 149
|
170
....*....|
gi 1935375888 235 KGMFEQAGFE 244
Cdd:pfam13489 150 KRLLEEAGFE 159
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
66-211 |
2.74e-09 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 54.95 E-value: 2.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 66 RYTIDCSGVRAGHKVLDIAGGTGdLTAKFSRMVGPTgsVTLADINLSMLKVGRDKLRDKGLvSNIDYVQADAESLPFPDN 145
Cdd:COG1041 16 RALVNLAGAKEGDTVLDPFCGTG-TILIEAGLLGRR--VIGSDIDPKMVEGARENLEHYGY-EDADVIRGDARDLPLADE 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1935375888 146 TFD-VVT-MAFGLRNVTEK-------QNALNSIYRVLKPGGRlLVLEFSKPASEHLSKLYdvysFHILPRMGQVV 211
Cdd:COG1041 92 SVDaIVTdPPYGRSSKISGeellelyEKALEEAARVLKPGGR-VVIVTPRDIDELLEEAG----FKVLERHEQRV 161
|
|
| PLN02490 |
PLN02490 |
MPBQ/MSBQ methyltransferase |
79-178 |
2.49e-08 |
|
MPBQ/MSBQ methyltransferase
Pssm-ID: 215270 [Multi-domain] Cd Length: 340 Bit Score: 53.74 E-value: 2.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 79 KVLDIAGGTGDLTAKFSRMVGPtGSVTLADINLSMLKvgrdKLRDKGLVSNIDYVQADAESLPFPDNTFDVVTMAFGLRN 158
Cdd:PLN02490 116 KVVDVGGGTGFTTLGIVKHVDA-KNVTILDQSPHQLA----KAKQKEPLKECKIIEGDAEDLPFPTDYADRYVSAGSIEY 190
|
90 100
....*....|....*....|
gi 1935375888 159 VTEKQNALNSIYRVLKPGGR 178
Cdd:PLN02490 191 WPDPQRGIKEAYRVLKIGGK 210
|
|
| PRK05785 |
PRK05785 |
hypothetical protein; Provisional |
41-240 |
2.96e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 235607 [Multi-domain] Cd Length: 226 Bit Score: 52.77 E-value: 2.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 41 VFDSVAAKYDVMNDLMSLGVHRLWKRYTIDCSGVRAGH--KVLDIAGGTGDLTAKFSRMVgpTGSVTLADINLSMLKVGr 118
Cdd:PRK05785 14 AYNKIPKAYDRANRFISFNQDVRWRAELVKTILKYCGRpkKVLDVAAGKGELSYHFKKVF--KYYVVALDYAENMLKMN- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 119 dklrdkgLVSNiDYVQADAESLPFPDNTFDVVTMAFGLRNVTEKQNALNSIYRVLKpgGRLLVLEFSKPASEHLSKLYDV 198
Cdd:PRK05785 91 -------LVAD-DKVVGSFEALPFRDKSFDVVMSSFALHASDNIEKVIAEFTRVSR--KQVGFIAMGKPDNVIKRKYLSF 160
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1935375888 199 YSFHILPRMGQVVANDEESYRYLAESIRMHPDQETLKGMFEQ 240
Cdd:PRK05785 161 YLRYIMPYIACLAGAKCRDYKYIYYIYERLPTNSFHREIFEK 202
|
|
| COG4076 |
COG4076 |
Predicted RNA methylase [General function prediction only]; |
74-180 |
9.34e-07 |
|
Predicted RNA methylase [General function prediction only];
Pssm-ID: 443253 [Multi-domain] Cd Length: 230 Bit Score: 48.49 E-value: 9.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 74 VRAGHKVLDIAGGTGdLTAKFSRMVGPtGSVTLADINLSMLKVGRDKLRDKGLVSNIDYVQADAESLPFPdNTFDVV--- 150
Cdd:COG4076 33 VKPGDVVLDIGTGSG-LLSMLAARAGA-KKVYAVEVNPDIAAVARRIIAANGLSDRITVINADATDLDLP-EKADVIise 109
|
90 100 110
....*....|....*....|....*....|..
gi 1935375888 151 TMAFGLrnVTEKQ--NALNSIYRVLKPGGRLL 180
Cdd:COG4076 110 MLDTAL--LDEGQvpILNHARKRLLKPGGRII 139
|
|
| PLN02244 |
PLN02244 |
tocopherol O-methyltransferase |
79-181 |
1.21e-06 |
|
tocopherol O-methyltransferase
Pssm-ID: 215135 [Multi-domain] Cd Length: 340 Bit Score: 48.97 E-value: 1.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 79 KVLDIAGGTGD----LTAKFSRMVgpTGsvtladINLSMLKVGR--DKLRDKGLVSNIDYVQADAESLPFPDNTFDVV-T 151
Cdd:PLN02244 121 RIVDVGCGIGGssryLARKYGANV--KG------ITLSPVQAARanALAAAQGLSDKVSFQVADALNQPFEDGQFDLVwS 192
|
90 100 110
....*....|....*....|....*....|
gi 1935375888 152 MAFGlRNVTEKQNALNSIYRVLKPGGRLLV 181
Cdd:PLN02244 193 MESG-EHMPDKRKFVQELARVAAPGGRIII 221
|
|
| COG2263 |
COG2263 |
Predicted RNA methylase [General function prediction only]; |
67-152 |
2.20e-06 |
|
Predicted RNA methylase [General function prediction only];
Pssm-ID: 441864 [Multi-domain] Cd Length: 199 Bit Score: 47.21 E-value: 2.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 67 YTIDCSGVRAGHKVLDIAGGTGDLtAKFSRMVGPTgSVTLADINLSMLKVGRDKLRDKGlvSNIDYVQADAESLPfPDNT 146
Cdd:COG2263 36 HLAYLRGDIEGKTVLDLGCGTGML-AIGAALLGAK-KVVGVDIDPEALEIARENAERLG--VRVDFIRADVTRIP-LGGS 110
|
....*.
gi 1935375888 147 FDVVTM 152
Cdd:COG2263 111 VDTVVM 116
|
|
| PCMT |
pfam01135 |
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); |
73-181 |
4.34e-06 |
|
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
Pssm-ID: 395902 [Multi-domain] Cd Length: 205 Bit Score: 46.21 E-value: 4.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 73 GVRAGHKVLDIAGGTGDLTAKFSRMVGPTGSVTLADINLSMLKVGRDKLRDKGLvSNIDYVQADAeSLPFPDNT-FDVVT 151
Cdd:pfam01135 70 ELKPGMRVLEIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRNLEKLGL-ENVIVVVGDG-RQGWPEFApYDAIH 147
|
90 100 110
....*....|....*....|....*....|
gi 1935375888 152 MAFGLRNVTEkqnalnSIYRVLKPGGRLLV 181
Cdd:pfam01135 148 VGAAAPEIPE------ALIDQLKEGGRLVI 171
|
|
| PLN02336 |
PLN02336 |
phosphoethanolamine N-methyltransferase |
74-190 |
6.10e-06 |
|
phosphoethanolamine N-methyltransferase
Pssm-ID: 177970 [Multi-domain] Cd Length: 475 Bit Score: 47.05 E-value: 6.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 74 VRAGHKVLD----IAGGTGDLTAKFS-RMVGptgsvtlADINLSMLKVGRDklRDKGLVSNIDYVQADAESLPFPDNTFD 148
Cdd:PLN02336 264 LKPGQKVLDvgcgIGGGDFYMAENFDvHVVG-------IDLSVNMISFALE--RAIGRKCSVEFEVADCTKKTYPDNSFD 334
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1935375888 149 VVTMAFGLRNVTEKQNALNSIYRVLKPGGRLLVLEFSK----PASE 190
Cdd:PLN02336 335 VIYSRDTILHIQDKPALFRSFFKWLKPGGKVLISDYCRspgtPSPE 380
|
|
| PRK13943 |
PRK13943 |
protein-L-isoaspartate O-methyltransferase; Provisional |
77-181 |
6.20e-06 |
|
protein-L-isoaspartate O-methyltransferase; Provisional
Pssm-ID: 237568 [Multi-domain] Cd Length: 322 Bit Score: 46.76 E-value: 6.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 77 GHKVLDIAGGTGDLTAKFSRMVGPTGSVTLADINLSMLKVGRDKLRDKGlVSNIDYVQADAESLPFPDNTFDVVTMAFGL 156
Cdd:PRK13943 81 GMRVLEIGGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKRNVRRLG-IENVIFVCGDGYYGVPEFAPYDVIFVTVGV 159
|
90 100
....*....|....*....|....*
gi 1935375888 157 RNVTEkqnalnSIYRVLKPGGRLLV 181
Cdd:PRK13943 160 DEVPE------TWFTQLKEGGRVIV 178
|
|
| Pcm |
COG2518 |
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ... |
74-181 |
6.28e-06 |
|
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 442008 [Multi-domain] Cd Length: 197 Bit Score: 45.85 E-value: 6.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 74 VRAGHKVLDIAGGTGDLTAKFSRMVgptGSVTLADINLSMLKVGRDKLRDKGLvSNIDYVQADAeSLPFPDN-TFDVVTM 152
Cdd:COG2518 64 LKPGDRVLEIGTGSGYQAAVLARLA---GRVYSVERDPELAERARERLAALGY-DNVTVRVGDG-ALGWPEHaPFDRIIV 138
|
90 100 110
....*....|....*....|....*....|..
gi 1935375888 153 AFGLRNVTE---KQnalnsiyrvLKPGGRLLV 181
Cdd:COG2518 139 TAAAPEVPEallEQ---------LAPGGRLVA 161
|
|
| UbiG |
TIGR01983 |
ubiquinone biosynthesis O-methyltransferase; This model represents an O-methyltransferase ... |
76-181 |
1.06e-05 |
|
ubiquinone biosynthesis O-methyltransferase; This model represents an O-methyltransferase believed to act at two points in the ubiquinone biosynthetic pathway in bacteria (UbiG) and fungi (COQ3). A separate methylase (MenG/UbiE) catalyzes the single C-methylation step. The most commonly used names for genes in this family do not indicate whether this gene is an O-methyl, or C-methyl transferase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 273910 Cd Length: 224 Bit Score: 45.36 E-value: 1.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 76 AGHKVLDIAGGTGDLTAKFSRMvgpTGSVTLADINLSMLKVGRDKLRDKGLvsNIDYVQADAESLPF-PDNTFDVVTMAF 154
Cdd:TIGR01983 46 DGLRVLDVGCGGGLLSEPLARL---GANVTGIDASEENIEVAKLHAKKDPL--QIDYRCTTVEDLAEkKAGSFDVVTCME 120
|
90 100
....*....|....*....|....*..
gi 1935375888 155 GLRNVTEKQNALNSIYRVLKPGGRLLV 181
Cdd:TIGR01983 121 VLEHVPDPQAFIRACAQLLKPGGILFF 147
|
|
| PRK11036 |
PRK11036 |
tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM; |
80-179 |
4.59e-05 |
|
tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM;
Pssm-ID: 182918 Cd Length: 255 Bit Score: 43.80 E-value: 4.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 80 VLDIAGGTGDLTAKFSRMvgptG-SVTLADINLSMLKVGRDKLRDKGLVSNIDYVQADAESL-PFPDNTFDVVTMAFGLR 157
Cdd:PRK11036 48 VLDAGGGEGQTAIKLAEL----GhQVILCDLSAEMIQRAKQAAEAKGVSDNMQFIHCAAQDIaQHLETPVDLILFHAVLE 123
|
90 100
....*....|....*....|..
gi 1935375888 158 NVTEKQNALNSIYRVLKPGGRL 179
Cdd:PRK11036 124 WVADPKSVLQTLWSVLRPGGAL 145
|
|
| COG4627 |
COG4627 |
Predicted SAM-depedendent methyltransferase [General function prediction only]; |
128-228 |
8.32e-05 |
|
Predicted SAM-depedendent methyltransferase [General function prediction only];
Pssm-ID: 443666 [Multi-domain] Cd Length: 161 Bit Score: 41.78 E-value: 8.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 128 SNIDYVQADAESLPFPDNTFDVVTMA-----FGLRNVtekQNALNSIYRVLKPGGRLLV----LEFSKPASEHLSKLYDV 198
Cdd:COG4627 28 PGVDIVGDLTDPLPFPDNSVDAIYSShvlehLDYEEA---PLALKECYRVLKPGGILRIvvpdLEHVARLYLAEYDAALD 104
|
90 100 110
....*....|....*....|....*....|
gi 1935375888 199 YSFHIlpRMGQVVANDEESYRYLAESIRMH 228
Cdd:COG4627 105 VAELR--LAGPIDPLGIILGERLAGLAARH 132
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
74-181 |
2.25e-04 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 40.65 E-value: 2.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 74 VRAGHKVLDIAGGTGDLTAKFSRMvGPTGSVTLADINLSMLKVGRDKLRDKGLvSNIDYVQADAESlPFPDNTFDVVTM- 152
Cdd:pfam05175 29 KDLSGKVLDLGCGAGVLGAALAKE-SPDAELTMVDINARALESARENLAANGL-ENGEVVASDVYS-GVEDGKFDLIISn 105
|
90 100 110
....*....|....*....|....*....|...
gi 1935375888 153 ----AFGLRNVTEKQNALNSIYRVLKPGGRLLV 181
Cdd:pfam05175 106 ppfhAGLATTYNVAQRFIADAKRHLRPGGELWI 138
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
79-181 |
6.46e-04 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 39.79 E-value: 6.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 79 KVLDIAGGTGDLTAKFSRMvGPTGSVTLADINLSMLKVGRDKLRDKGLvSNIDYVQADAESlPFPDNTFDVVTM------ 152
Cdd:COG2813 52 RVLDLGCGYGVIGLALAKR-NPEARVTLVDVNARAVELARANAAANGL-ENVEVLWSDGLS-GVPDGSFDLILSnppfha 128
|
90 100 110
....*....|....*....|....*....|..
gi 1935375888 153 -AFGLRNVTEK--QNAlnsiYRVLKPGGRLLV 181
Cdd:COG2813 129 gRAVDKEVAHAliADA----ARHLRPGGELWL 156
|
|
| PKS_MT |
smart00828 |
Methyltransferase in polyketide synthase (PKS) enzymes; |
79-184 |
1.05e-03 |
|
Methyltransferase in polyketide synthase (PKS) enzymes;
Pssm-ID: 214839 [Multi-domain] Cd Length: 224 Bit Score: 39.32 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 79 KVLDIAGGTG----DLTAKFS--RMVGPTGSVTLAdinlsmlKVGRDKLRDKGLVSNIDYVQADAESLPFPDnTFDVVtm 152
Cdd:smart00828 2 RVLDFGCGYGsdliDLAERHPhlQLHGYTISPEQA-------EVGRERIRALGLQGRIRIFYRDSAKDPFPD-TYDLV-- 71
|
90 100 110
....*....|....*....|....*....|....*
gi 1935375888 153 aFGLRNVT---EKQNALNSIYRVLKPGGRLLVLEF 184
Cdd:smart00828 72 -FGFEVIHhikDKMDLFSNISRHLKDGGHLVLADF 105
|
|
| PTZ00098 |
PTZ00098 |
phosphoethanolamine N-methyltransferase; Provisional |
76-199 |
2.44e-03 |
|
phosphoethanolamine N-methyltransferase; Provisional
Pssm-ID: 173391 [Multi-domain] Cd Length: 263 Bit Score: 38.41 E-value: 2.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 76 AGHKVLDIAGGTGDLTAKFSRMVGptGSVTLADINLSMLKVGRDKLRDKglvSNIDYVQADAESLPFPDNTFDVVTMAFG 155
Cdd:PTZ00098 52 ENSKVLDIGSGLGGGCKYINEKYG--AHVHGVDICEKMVNIAKLRNSDK---NKIEFEANDILKKDFPENTFDMIYSRDA 126
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1935375888 156 LRNVT--EKQNALNSIYRVLKPGGRLLVLEFSKPASEHLSKLYDVY 199
Cdd:PTZ00098 127 ILHLSyaDKKKLFEKCYKWLKPNGILLITDYCADKIENWDEEFKAY 172
|
|
| cbiT |
PRK00377 |
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional |
74-195 |
2.53e-03 |
|
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
Pssm-ID: 234740 Cd Length: 198 Bit Score: 37.85 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 74 VRAGHKVLDIAGGTGDLTAKFSRMVGPTGSVTLADINLSMLKVGRDKLRDKGLVSNIDYVQADA-ESLPFPDNTFDVVTM 152
Cdd:PRK00377 38 LRKGDMILDIGCGTGSVTVEASLLVGETGKVYAVDKDEKAINLTRRNAEKFGVLNNIVLIKGEApEILFTINEKFDRIFI 117
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1935375888 153 AFGLRNVTEkqnALNSIYRVLKPGGRLLV----LEFSKPASEHLSKL 195
Cdd:PRK00377 118 GGGSEKLKE---IISASWEIIKKGGRIVIdailLETVNNALSALENI 161
|
|
| rADc |
smart00650 |
Ribosomal RNA adenine dimethylases; |
69-150 |
4.60e-03 |
|
Ribosomal RNA adenine dimethylases;
Pssm-ID: 128898 Cd Length: 169 Bit Score: 37.11 E-value: 4.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 69 IDCSGVRAGHKVLDIAGGTGDLTAKFSRMVGPtgsVTLADINLSMLKVGRDKLRDKglvSNIDYVQADAESLPFPDNTFD 148
Cdd:smart00650 6 VRAANLRPGDTVLEIGPGKGALTEELLERAKR---VTAIEIDPRLAPRLREKFAAA---DNLTVIHGDALKFDLPKLQPY 79
|
..
gi 1935375888 149 VV 150
Cdd:smart00650 80 KV 81
|
|
| PRK15451 |
PRK15451 |
carboxy-S-adenosyl-L-methionine synthase CmoA; |
74-247 |
5.04e-03 |
|
carboxy-S-adenosyl-L-methionine synthase CmoA;
Pssm-ID: 185348 Cd Length: 247 Bit Score: 37.31 E-value: 5.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 74 VRAGHKVLDIAGGTGDLTAKFSRMVGPTGSVTLA-DINLSMLKVGRDKLRDKGLVSNIDYVQADAESLPFPDNTFDVVTM 152
Cdd:PRK15451 54 VQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAiDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNF 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 153 AFGLRNVTEKQNALNSIYRVLKPGGRLLVLE-FSKPASEHLSKLYDVYsfHILPRMGQVVANDEESYRYLAESIRMHPDQ 231
Cdd:PRK15451 134 TLQFLEPSERQALLDKIYQGLNPGGALVLSEkFSFEDAKVGELLFNMH--HDFKRANGYSELEISQKRSMLENVMLTDSV 211
|
170
....*....|....*.
gi 1935375888 232 ETLKGMFEQAGFEQCD 247
Cdd:PRK15451 212 ETHKARLHKAGFEHSE 227
|
|
| GCD14 |
pfam08704 |
tRNA methyltransferase complex GCD14 subunit; GCD14 is a subunit of the tRNA methyltransferase ... |
61-143 |
5.06e-03 |
|
tRNA methyltransferase complex GCD14 subunit; GCD14 is a subunit of the tRNA methyltransferase complex and is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA.
Pssm-ID: 312288 Cd Length: 242 Bit Score: 37.47 E-value: 5.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 61 HRLWKRYTIDCS------GVRAGHKVLDIAGGTGDLTAKFSRMVGPTGSVTLADINLSMLKVGRDKLRDKGLVSNIDYVQ 134
Cdd:pfam08704 19 HRTQILYTPDISlitmmlELRPGSVVCESGTGSGSLSHAIIRTVAPTGHLFTFEFHEQRADKAREEFREHGIDQLVTVTH 98
|
....*....
gi 1935375888 135 ADAESLPFP 143
Cdd:pfam08704 99 RDVCKEGFL 107
|
|
| MDR |
cd05188 |
Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; ... |
72-182 |
5.71e-03 |
|
Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; The medium chain reductase/dehydrogenases (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH) , quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines. Other MDR members have only a catalytic zinc, and some contain no coordinated zinc.
Pssm-ID: 176178 [Multi-domain] Cd Length: 271 Bit Score: 37.30 E-value: 5.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935375888 72 SGVRAGHKVLDI-AGGTGDLTAKFSRMVGPTgsVTLADINLSMLkvgrDKLRDKGLVSNIDYVQAD--AESLPFPDNTFD 148
Cdd:cd05188 130 GVLKPGDTVLVLgAGGVGLLAAQLAKAAGAR--VIVTDRSDEKL----ELAKELGADHVIDYKEEDleEELRLTGGGGAD 203
|
90 100 110
....*....|....*....|....*....|....
gi 1935375888 149 VVTMAFGlrnvteKQNALNSIYRVLKPGGRLLVL 182
Cdd:cd05188 204 VVIDAVG------GPETLAQALRLLRPGGRIVVV 231
|
|
| PRK07580 |
PRK07580 |
Mg-protoporphyrin IX methyl transferase; Validated |
76-150 |
7.29e-03 |
|
Mg-protoporphyrin IX methyl transferase; Validated
Pssm-ID: 236059 [Multi-domain] Cd Length: 230 Bit Score: 36.74 E-value: 7.29e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1935375888 76 AGHKVLDiAG-GTGDLTAKFSRMvgptG-SVTLADINLSMLKVGRDKLRDKGLVSNIDYVQADAESLpfpDNTFDVV 150
Cdd:PRK07580 63 TGLRILD-AGcGVGSLSIPLARR----GaKVVASDISPQMVEEARERAPEAGLAGNITFEVGDLESL---LGRFDTV 131
|
|
| |
