|
Name |
Accession |
Description |
Interval |
E-value |
| Pyridoxal_deC |
pfam00282 |
Pyridoxal-dependent decarboxylase conserved domain; |
91-460 |
1.67e-158 |
|
Pyridoxal-dependent decarboxylase conserved domain;
Pssm-ID: 395219 Cd Length: 373 Bit Score: 456.49 E-value: 1.67e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 91 PEEMVKILDLELHDEPLPLKQLLEDCKTALKYQVKTGH-PHFFNQLSCGLDIISLAGEWLTAAANTNMFTYEIAPVFILM 169
Cdd:pfam00282 1 PGYLKPLLPLAAPIIPEPELQIDGDIRRNLMPGVTTWHsPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 170 ENIVLEKMRSMIGW------KTGDSILAPGGSVSNLYAFLAARHRKFPQYKEKGL----SSIPGQLVMFTSDQCHYSVKS 239
Cdd:pfam00282 81 ENVVMNWLGEMLGLpaeflgQEGGGVLQPGSSESNLLALLAARTKWIKRMKAAGKpadsSGILAKLVAYTSDQAHSSIEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 240 CASVCGLGtdyCVCVPSDERGRMIPAQLERLVRYHKDKGNVPFFVNATSGTTVLGAFDPLMEIADICQKYDMWMHVDAAW 319
Cdd:pfam00282 161 AALYGGVK---LREIPSDDNGKMRGMDLEKAIEEDKENGLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAY 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 320 GGGLLFSKKYRHpRLTGIERADSVTWNPHKLMGTLLQCSTVHFKYEGILLSCNAMSAEYLFMTDKIydpqYDTGDKVIQC 399
Cdd:pfam00282 238 GGSAFICPEFRH-WLFGIERADSITFNPHKWMLVLLDCSAVWVKDKEALQQAFQFNPLYLGHTDSA----YDTGHKQIPL 312
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1931223899 400 GRHNDIFKLWLQWRGKGTSGFERLMDRLMELSEYMVRRIKEQPDkFHLILEPEMVNVSFWY 460
Cdd:pfam00282 313 SRRFRILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIRKDGR-FEICAEVGLGLVCFRL 372
|
|
| GadA |
COG0076 |
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ... |
59-536 |
1.58e-121 |
|
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis
Pssm-ID: 439846 [Multi-domain] Cd Length: 460 Bit Score: 365.31 E-value: 1.58e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 59 QTREFLARVIDVLLDYVQkvndRNEKILEFKMPEEMVKILDLELHDEPLPLKQLLED-CKTALKYQVKTGHPHFFNQLSC 137
Cdd:COG0076 1 EFRALLHQALDLAADYLA----GLDRPVFGPSPEELRAALDEPLPEEGLPPEEALAElEDLVLPGSVDWNHPRFLAFVTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 138 GLDIISLAGEWLTAAANTNMFTYEIAPVFILMENIVLEKMRSMIGW-KTGDSILAPGGSVSNLYAFLAARHRKFPQY-KE 215
Cdd:COG0076 77 GTTPAALAADLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLpEGAGGVFTSGGTEANLLALLAARDRALARRvRA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 216 KGLSSIPgQLVMFTSDQCHYSVKSCASVCGLGTDYCVCVPSDERGRMIPAQLERLVRYHKDKGNVPFFVNATSGTTVLGA 295
Cdd:COG0076 157 EGLPGAP-RPRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 296 FDPLMEIADICQKYDMWMHVDAAWGGGLLFSKKYRHpRLTGIERADSVTWNPHKLMGTLLQCSTVHFKYEGILLSCNAMS 375
Cdd:COG0076 236 IDPLAEIADIAREHGLWLHVDAAYGGFALPSPELRH-LLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREAFSFH 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 376 AEYLFMTDkiyDPQYDTGDKVIQCGRHNDIFKLWLQWRGKGTSGFERLMDRLMELSEYMVRRIKEQPDkFHLILEPEMVN 455
Cdd:COG0076 315 ASYLGPAD---DGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPG-FELLAPPELNI 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 456 VSFWYLPKQLRGIPHDaNKELRLgkvcaklkgKMMQAGTIMVGYQPDDRRPNfFRNIISSAAVTEKDVDFLLSEMDRLGQ 535
Cdd:COG0076 391 VCFRYKPAGLDEEDAL-NYALRD---------RLRARGRAFLSPTKLDGRVV-LRLVVLNPRTTEDDVDALLDDLREAAA 459
|
.
gi 1931223899 536 D 536
Cdd:COG0076 460 E 460
|
|
| DOPA_deC_like |
cd06450 |
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
131-533 |
8.20e-115 |
|
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.
Pssm-ID: 99743 [Multi-domain] Cd Length: 345 Bit Score: 343.80 E-value: 8.20e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 131 FFNQLSCGLDIISLAGEWLTAAANTNMFTYEIAPVFILMENIVLEKMRSMIGW--KTGDSILAPGGSVSNLYAFLAARHR 208
Cdd:cd06450 1 FLAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLpsEDADGVFTSGGSESNLLALLAARDR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 209 KFPQYKEKGLSSIPgQLVMFTSDQCHYSV-KSCAsvcgLGTDYCVCVPSDERGRMIPAQLERLVRYHKDKGNVPFFVNAT 287
Cdd:cd06450 81 ARKRLKAGGGRGID-KLVIVCSDQAHVSVeKAAA----YLDVKVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPIMVVAT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 288 SGTTVLGAFDPLMEIADICQKYDMWMHVDAAWGGGLLFSKKYRHpRLTGIERADSVTWNPHKLMGTLLQCSTVHFKyegi 367
Cdd:cd06450 156 AGTTDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRH-LDFGIERVDSISVDPHKYGLVPLGCSAVLVR---- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 368 llscnamsaeylfmtdkiydpqydtgdkviqcgrhndIFKLWLQWRGKGTSGFERLMDRLMELSEYMVRRIKEQPdKFHL 447
Cdd:cd06450 231 -------------------------------------ALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADP-GFEL 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 448 ILEPEMVNVSFWYLPKQlrgiphdankelRLGKVCAKLKGKMMQAGTIMVGYQPDDrRPNFFRNIISSAAVTEKDVDFLL 527
Cdd:cd06450 273 LGEPNLSLVCFRLKPSV------------KLDELNYDLSDRLNERGGWHVPATTLG-GPNVLRFVVTNPLTTRDDADALL 339
|
....*.
gi 1931223899 528 SEMDRL 533
Cdd:cd06450 340 EDIERA 345
|
|
| PLN02880 |
PLN02880 |
tyrosine decarboxylase |
59-462 |
7.38e-35 |
|
tyrosine decarboxylase
Pssm-ID: 215475 [Multi-domain] Cd Length: 490 Bit Score: 136.96 E-value: 7.38e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 59 QTREFLARVIDVLLDYVQKVndRNEKILEFKMPEEMVKILDLELHDEPLPLKQLLEDCKTALKYQVKTGH-PHFFNQLSC 137
Cdd:PLN02880 14 QLRECGHRMVDFIADYYKSI--ENFPVLSQVQPGYLRELLPDSAPNQPETLDQVLDDVQAKILPGVTHWQsPNYFAYYPS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 138 GLDIISLAGEWLTAAANTNMFTYEIAPVFILMENIVLEKMRSMIgwKTGDSILAPG-------GSVSN--LYAFLAARHR 208
Cdd:PLN02880 92 NSSVAGFLGEMLSAGLNIVGFSWITSPAATELEMIVLDWLAKLL--NLPEQFLSTGngggviqGTASEavLVVLLAARDR 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 209 KFPQYKEKGLSsipgQLVMFTSDQCHYSVKSCASVCGLGTDYCVCVPSDERGR--MIPAQLERLVRYHKDKGNVPFFVNA 286
Cdd:PLN02880 170 VLRKVGKNALE----KLVVYASDQTHSALQKACQIAGIHPENCRLLKTDSSTNyaLAPELLSEAISTDLSSGLIPFFLCA 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 287 TSGTTVLGAFDPLMEIADICQKYDMWMHVDAAWGGGLLFSKKYRHpRLTGIERADSVTWNPHKLMGTLLQCSTVHFKYEG 366
Cdd:PLN02880 246 TVGTTSSTAVDPLLELGKIAKSNGMWFHVDAAYAGSACICPEYRH-YIDGVEEADSFNMNAHKWFLTNFDCSLLWVKDRN 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 367 ILLscNAMSAEYLFMTDKIYDPQ--YDTGDKVIQCGRHNDIFKLWLQWRGKGTSGFERLMDRLMELSEYMVRRIKEQPdK 444
Cdd:PLN02880 325 ALI--QSLSTNPEFLKNKASQANsvVDYKDWQIPLGRRFRSLKLWMVLRLYGVENLQSYIRNHIKLAKEFEQLVAQDS-R 401
|
410
....*....|....*...
gi 1931223899 445 FHLILEPEMVNVSFWYLP 462
Cdd:PLN02880 402 FEVVTPRIFSLVCFRLVP 419
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Pyridoxal_deC |
pfam00282 |
Pyridoxal-dependent decarboxylase conserved domain; |
91-460 |
1.67e-158 |
|
Pyridoxal-dependent decarboxylase conserved domain;
Pssm-ID: 395219 Cd Length: 373 Bit Score: 456.49 E-value: 1.67e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 91 PEEMVKILDLELHDEPLPLKQLLEDCKTALKYQVKTGH-PHFFNQLSCGLDIISLAGEWLTAAANTNMFTYEIAPVFILM 169
Cdd:pfam00282 1 PGYLKPLLPLAAPIIPEPELQIDGDIRRNLMPGVTTWHsPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 170 ENIVLEKMRSMIGW------KTGDSILAPGGSVSNLYAFLAARHRKFPQYKEKGL----SSIPGQLVMFTSDQCHYSVKS 239
Cdd:pfam00282 81 ENVVMNWLGEMLGLpaeflgQEGGGVLQPGSSESNLLALLAARTKWIKRMKAAGKpadsSGILAKLVAYTSDQAHSSIEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 240 CASVCGLGtdyCVCVPSDERGRMIPAQLERLVRYHKDKGNVPFFVNATSGTTVLGAFDPLMEIADICQKYDMWMHVDAAW 319
Cdd:pfam00282 161 AALYGGVK---LREIPSDDNGKMRGMDLEKAIEEDKENGLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAY 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 320 GGGLLFSKKYRHpRLTGIERADSVTWNPHKLMGTLLQCSTVHFKYEGILLSCNAMSAEYLFMTDKIydpqYDTGDKVIQC 399
Cdd:pfam00282 238 GGSAFICPEFRH-WLFGIERADSITFNPHKWMLVLLDCSAVWVKDKEALQQAFQFNPLYLGHTDSA----YDTGHKQIPL 312
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1931223899 400 GRHNDIFKLWLQWRGKGTSGFERLMDRLMELSEYMVRRIKEQPDkFHLILEPEMVNVSFWY 460
Cdd:pfam00282 313 SRRFRILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIRKDGR-FEICAEVGLGLVCFRL 372
|
|
| GadA |
COG0076 |
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ... |
59-536 |
1.58e-121 |
|
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis
Pssm-ID: 439846 [Multi-domain] Cd Length: 460 Bit Score: 365.31 E-value: 1.58e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 59 QTREFLARVIDVLLDYVQkvndRNEKILEFKMPEEMVKILDLELHDEPLPLKQLLED-CKTALKYQVKTGHPHFFNQLSC 137
Cdd:COG0076 1 EFRALLHQALDLAADYLA----GLDRPVFGPSPEELRAALDEPLPEEGLPPEEALAElEDLVLPGSVDWNHPRFLAFVTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 138 GLDIISLAGEWLTAAANTNMFTYEIAPVFILMENIVLEKMRSMIGW-KTGDSILAPGGSVSNLYAFLAARHRKFPQY-KE 215
Cdd:COG0076 77 GTTPAALAADLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLpEGAGGVFTSGGTEANLLALLAARDRALARRvRA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 216 KGLSSIPgQLVMFTSDQCHYSVKSCASVCGLGTDYCVCVPSDERGRMIPAQLERLVRYHKDKGNVPFFVNATSGTTVLGA 295
Cdd:COG0076 157 EGLPGAP-RPRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 296 FDPLMEIADICQKYDMWMHVDAAWGGGLLFSKKYRHpRLTGIERADSVTWNPHKLMGTLLQCSTVHFKYEGILLSCNAMS 375
Cdd:COG0076 236 IDPLAEIADIAREHGLWLHVDAAYGGFALPSPELRH-LLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREAFSFH 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 376 AEYLFMTDkiyDPQYDTGDKVIQCGRHNDIFKLWLQWRGKGTSGFERLMDRLMELSEYMVRRIKEQPDkFHLILEPEMVN 455
Cdd:COG0076 315 ASYLGPAD---DGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPG-FELLAPPELNI 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 456 VSFWYLPKQLRGIPHDaNKELRLgkvcaklkgKMMQAGTIMVGYQPDDRRPNfFRNIISSAAVTEKDVDFLLSEMDRLGQ 535
Cdd:COG0076 391 VCFRYKPAGLDEEDAL-NYALRD---------RLRARGRAFLSPTKLDGRVV-LRLVVLNPRTTEDDVDALLDDLREAAA 459
|
.
gi 1931223899 536 D 536
Cdd:COG0076 460 E 460
|
|
| DOPA_deC_like |
cd06450 |
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
131-533 |
8.20e-115 |
|
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.
Pssm-ID: 99743 [Multi-domain] Cd Length: 345 Bit Score: 343.80 E-value: 8.20e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 131 FFNQLSCGLDIISLAGEWLTAAANTNMFTYEIAPVFILMENIVLEKMRSMIGW--KTGDSILAPGGSVSNLYAFLAARHR 208
Cdd:cd06450 1 FLAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLpsEDADGVFTSGGSESNLLALLAARDR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 209 KFPQYKEKGLSSIPgQLVMFTSDQCHYSV-KSCAsvcgLGTDYCVCVPSDERGRMIPAQLERLVRYHKDKGNVPFFVNAT 287
Cdd:cd06450 81 ARKRLKAGGGRGID-KLVIVCSDQAHVSVeKAAA----YLDVKVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPIMVVAT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 288 SGTTVLGAFDPLMEIADICQKYDMWMHVDAAWGGGLLFSKKYRHpRLTGIERADSVTWNPHKLMGTLLQCSTVHFKyegi 367
Cdd:cd06450 156 AGTTDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRH-LDFGIERVDSISVDPHKYGLVPLGCSAVLVR---- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 368 llscnamsaeylfmtdkiydpqydtgdkviqcgrhndIFKLWLQWRGKGTSGFERLMDRLMELSEYMVRRIKEQPdKFHL 447
Cdd:cd06450 231 -------------------------------------ALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADP-GFEL 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 448 ILEPEMVNVSFWYLPKQlrgiphdankelRLGKVCAKLKGKMMQAGTIMVGYQPDDrRPNFFRNIISSAAVTEKDVDFLL 527
Cdd:cd06450 273 LGEPNLSLVCFRLKPSV------------KLDELNYDLSDRLNERGGWHVPATTLG-GPNVLRFVVTNPLTTRDDADALL 339
|
....*.
gi 1931223899 528 SEMDRL 533
Cdd:cd06450 340 EDIERA 345
|
|
| PLN02880 |
PLN02880 |
tyrosine decarboxylase |
59-462 |
7.38e-35 |
|
tyrosine decarboxylase
Pssm-ID: 215475 [Multi-domain] Cd Length: 490 Bit Score: 136.96 E-value: 7.38e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 59 QTREFLARVIDVLLDYVQKVndRNEKILEFKMPEEMVKILDLELHDEPLPLKQLLEDCKTALKYQVKTGH-PHFFNQLSC 137
Cdd:PLN02880 14 QLRECGHRMVDFIADYYKSI--ENFPVLSQVQPGYLRELLPDSAPNQPETLDQVLDDVQAKILPGVTHWQsPNYFAYYPS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 138 GLDIISLAGEWLTAAANTNMFTYEIAPVFILMENIVLEKMRSMIgwKTGDSILAPG-------GSVSN--LYAFLAARHR 208
Cdd:PLN02880 92 NSSVAGFLGEMLSAGLNIVGFSWITSPAATELEMIVLDWLAKLL--NLPEQFLSTGngggviqGTASEavLVVLLAARDR 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 209 KFPQYKEKGLSsipgQLVMFTSDQCHYSVKSCASVCGLGTDYCVCVPSDERGR--MIPAQLERLVRYHKDKGNVPFFVNA 286
Cdd:PLN02880 170 VLRKVGKNALE----KLVVYASDQTHSALQKACQIAGIHPENCRLLKTDSSTNyaLAPELLSEAISTDLSSGLIPFFLCA 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 287 TSGTTVLGAFDPLMEIADICQKYDMWMHVDAAWGGGLLFSKKYRHpRLTGIERADSVTWNPHKLMGTLLQCSTVHFKYEG 366
Cdd:PLN02880 246 TVGTTSSTAVDPLLELGKIAKSNGMWFHVDAAYAGSACICPEYRH-YIDGVEEADSFNMNAHKWFLTNFDCSLLWVKDRN 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 367 ILLscNAMSAEYLFMTDKIYDPQ--YDTGDKVIQCGRHNDIFKLWLQWRGKGTSGFERLMDRLMELSEYMVRRIKEQPdK 444
Cdd:PLN02880 325 ALI--QSLSTNPEFLKNKASQANsvVDYKDWQIPLGRRFRSLKLWMVLRLYGVENLQSYIRNHIKLAKEFEQLVAQDS-R 401
|
410
....*....|....*...
gi 1931223899 445 FHLILEPEMVNVSFWYLP 462
Cdd:PLN02880 402 FEVVTPRIFSLVCFRLVP 419
|
|
| PLN02590 |
PLN02590 |
probable tyrosine decarboxylase |
67-475 |
3.42e-34 |
|
probable tyrosine decarboxylase
Pssm-ID: 178200 [Multi-domain] Cd Length: 539 Bit Score: 135.99 E-value: 3.42e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 67 VIDVLLDYVQKVNDRNEK--ILEFKMPEEMVKILDLELHDEPLPLKQLLEDCKTALKYQVKTGH-PHFFNQLSCGLDIIS 143
Cdd:PLN02590 66 MVDFIADYYKNLQDSPQDfpVLSQVQPGYLRDMLPDSAPERPESLKELLDDVSKKIMPGITHWQsPSYFAYYASSTSVAG 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 144 LAGEWLTAAANTNMFTYEIAPVFILMENIVLEKMRSMI-------GWKTGDSILAPGGSVSNLYAFLAARHRKFpqyKEK 216
Cdd:PLN02590 146 FLGEMLNAGLSVVGFTWLTSPAATELEIIVLDWLAKLLqlpdhflSTGNGGGVIQGTGCEAVLVVVLAARDRIL---KKV 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 217 GLSSIPgQLVMFTSDQCHYSVKSCASVCGLGTDYCVCVPSDERGR--MIPAQLERLVRYHKDKGNVPFFVNATSGTTVLG 294
Cdd:PLN02590 223 GKTLLP-QLVVYGSDQTHSSFRKACLIGGIHEENIRLLKTDSSTNygMPPESLEEAISHDLAKGFIPFFICATVGTTSSA 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 295 AFDPLMEIADICQKYDMWMHVDAAWGGGLLFSKKYRHpRLTGIERADSVTWNPHKLMGTLLQCSTVHFKYEGILLSCNAM 374
Cdd:PLN02590 302 AVDPLVPLGNIAKKYGIWLHVDAAYAGNACICPEYRK-FIDGIENADSFNMNAHKWLFANQTCSPLWVKDRYSLIDALKT 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 375 SAEYLFMTDKIYDPQYDTGDKVIQCGRHNDIFKLWLQWRGKGTSGFERLMDRLMELSEYMVRRIKEQPdkfHLilepEMV 454
Cdd:PLN02590 381 NPEYLEFKVSKKDTVVNYKDWQISLSRRFRSLKLWMVLRLYGSENLRNFIRDHVNLAKHFEDYVAQDP---SF----EVV 453
|
410 420
....*....|....*....|.
gi 1931223899 455 NVSFWYLpKQLRGIPHDANKE 475
Cdd:PLN02590 454 TTRYFSL-VCFRLAPVDGDED 473
|
|
| PRK02769 |
PRK02769 |
histidine decarboxylase; Provisional |
193-441 |
1.59e-15 |
|
histidine decarboxylase; Provisional
Pssm-ID: 235068 [Multi-domain] Cd Length: 380 Bit Score: 78.16 E-value: 1.59e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 193 GGSVSNLYAFLAARHRkFPQykekglssipgqLVMFTSDQCHYSVKSCASVcgLGTDYCVcVPSDERGRMIPAQLERLVR 272
Cdd:PRK02769 92 GGTEGNLYGCYLAREL-FPD------------GTLYYSKDTHYSVSKIARL--LRIKSRV-ITSLPNGEIDYDDLISKIK 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 273 YHKDKgnvPFFVNATSGTTVLGAFDPLMEIADICQKY---DMWMHVDAAWGGGLLFSKKYRHPrLTGIERADSVTWNPHK 349
Cdd:PRK02769 156 ENKNQ---PPIIFANIGTTMTGAIDNIKEIQEILKKIgidDYYIHADAALSGMILPFVNNPPP-FSFADGIDSIAISGHK 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 350 LMGTLLQCstvhfkyeGILLScnamsaeYLFMTDKIY-DPQY-DTGDKVIQCGR--HNDIFkLWLQWRGKGTSGFERLMD 425
Cdd:PRK02769 232 FIGSPMPC--------GIVLA-------KKKYVERISvDVDYiGSRDQTISGSRngHTALL-LWAAIRSLGSKGLRQRVQ 295
|
250
....*....|....*.
gi 1931223899 426 RLMELSEYMVRRIKEQ 441
Cdd:PRK02769 296 HCLDMAQYAVDRLQAN 311
|
|
| PLN03032 |
PLN03032 |
serine decarboxylase; Provisional |
194-440 |
1.65e-10 |
|
serine decarboxylase; Provisional
Pssm-ID: 166673 [Multi-domain] Cd Length: 374 Bit Score: 62.92 E-value: 1.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 194 GSVSNLYAFLAARHrKFPQYkekglssipgqlVMFTSDQCHYSVKSCASVCGLGtdyCVCVPSDERGRMIPAQLERLVRY 273
Cdd:PLN03032 94 GTEGNLHGILVGRE-VFPDG------------ILYASRESHYSVFKAARMYRME---AVKVPTLPSGEIDYDDLERALAK 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 274 HKDKgnvPFFVNATSGTTVLGAFDPLMEIADICQKYDM-----WMHVDAAWGGgLLFSKKYRHPRLTGIERADSVTWNPH 348
Cdd:PLN03032 158 NRDK---PAILNVNIGTTVKGAVDDLDRILRILKELGYtedrfYIHCDGALFG-LMMPFVSRAPEVTFRKPIGSVSVSGH 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 349 KLMGTLLQCSTVHFKYEGIllscNAMSA--EYLfmtdkiydpqyDTGDKVIQCGR--HNDIFkLWLQWRGKGTSGFERLM 424
Cdd:PLN03032 234 KFLGCPMPCGVALTRKKHV----KALSQnvEYL-----------NSRDATIMGSRngHAPLY-LWYTLRRKGYRGIKRDV 297
|
250
....*....|....*.
gi 1931223899 425 DRLMELSEYMVRRIKE 440
Cdd:PLN03032 298 QHCMRNAHYLKDRLTE 313
|
|
| PLN02263 |
PLN02263 |
serine decarboxylase |
226-440 |
6.42e-10 |
|
serine decarboxylase
Pssm-ID: 177904 [Multi-domain] Cd Length: 470 Bit Score: 61.37 E-value: 6.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 226 VMFTSDQCHYSVKSCASVCGLGtdyCVCVPSDERGRMIPAQLERLVRYHKDKgnvPFFVNATSGTTVLGAFDPLMEIADI 305
Cdd:PLN02263 180 ILYASRESHYSVFKAARMYRME---CVKVDTLVSGEIDCADFKAKLLANKDK---PAIINVNIGTTVKGAVDDLDLVIKT 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 306 CQK----YD-MWMHVDAAWGGGLL-FSKkyRHPRLTGIERADSVTWNPHKLMGTLLQCSTVHFKYEGI-LLSCNAmsaEY 378
Cdd:PLN02263 254 LEEcgfsQDrFYIHCDGALFGLMMpFVK--RAPKVTFKKPIGSVSVSGHKFVGCPMPCGVQITRMEHInVLSSNV---EY 328
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1931223899 379 LfmtdkiydpqyDTGDKVIQCGR--HNDIFkLWLQWRGKGTSGFERLMDRLMELSEYMVRRIKE 440
Cdd:PLN02263 329 L-----------ASRDATIMGSRngHAPIF-LWYTLNRKGYRGFQKEVQKCLRNAHYLKDRLRE 380
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
192-352 |
1.51e-09 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 57.01 E-value: 1.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 192 PGGSVSNLYAFLAARhrkfpqykekglssIPGQLVMFtSDQCHYSV-KSCASVCGLGTdycVCVPSDERGRMI--PAQLE 268
Cdd:cd01494 24 PSGTGANEAALLALL--------------GPGDEVIV-DANGHGSRyWVAAELAGAKP---VPVPVDDAGYGGldVAILE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 269 RLVRYHKdkgnvPFFVNATSGTTVLGAFDPLMEIADICQKYDMWMHVDAAWGGGLLFSKKYRHPRltgiERADSVTWNPH 348
Cdd:cd01494 86 ELKAKPN-----VALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGASPAPGVLIPE----GGADVVTFSLH 156
|
....
gi 1931223899 349 KLMG 352
Cdd:cd01494 157 KNLG 160
|
|
| Orn_deC_like |
cd00615 |
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
301-363 |
1.40e-06 |
|
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.
Pssm-ID: 99739 [Multi-domain] Cd Length: 294 Bit Score: 49.94 E-value: 1.40e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1931223899 301 EIADICQKYDMWMHVDAAWGGGLLFSKKYrhPRLTGIERADSVTWNPHKLMGTLLQCSTVHFK 363
Cdd:cd00615 174 KIVEEAHHRGLPVLVDEAHGAHFRFHPIL--PSSAAMAGADIVVQSTHKTLPALTQGSMIHVK 234
|
|
| LdcC |
COG1982 |
Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism]; |
301-460 |
2.53e-05 |
|
Arginine/lysine/ornithine decarboxylase [Amino acid transport and metabolism];
Pssm-ID: 441585 [Multi-domain] Cd Length: 486 Bit Score: 47.03 E-value: 2.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 301 EIADICQKYDMWMHVDAAWGGGLLFSKKYRHPRLT-GierADSVTWNPHKLMGTLLQCSTVHFKYEGI----LLSCNAM- 374
Cdd:COG1982 181 AIAELAHEHGIPVLVDEAHGAHFGFHPDLPRSAMEaG---ADLVVQSTHKTLGALTQSSMLHVKGGRVdherVNEALMLl 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931223899 375 ---SAEYLFMT--DkiydpqydtgdkviqCGRHndifklwlQWRGKGtsgfERLMDRLMELSEYMVRRIKEQPDkFHlIL 449
Cdd:COG1982 258 qstSPSYLLMAslD---------------VARR--------QMAGEG----EELLDEALELAIEARKEINKIPG-LY-VF 308
|
170
....*....|.
gi 1931223899 450 EPEMVNVSFWY 460
Cdd:COG1982 309 GPEDLGAPGVY 319
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
254-318 |
1.70e-03 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 40.69 E-value: 1.70e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1931223899 254 VPSDERGRMIPAQLERLVRyHKDKgnvpfFVNATSGTTVLGAFDPLMEIADICQKYDMWMHVDAA 318
Cdd:pfam00266 119 LPLDEDGLLDLDELEKLIT-PKTK-----LVAITHVSNVTGTIQPVPEIGKLAHQYGALVLVDAA 177
|
|
| |
