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Conserved domains on  [gi|1931045932|dbj|GHP01734|]
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leucine rich repeat-containing protein [Pycnococcus provasolii]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
133-365 1.13e-22

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 100.78  E-value: 1.13e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 133 TAKPAKSADIVESDRDGVLVTRRSGQLYVERTKQAKDAQPERLNLDRRHLDSCCLILNDERLRLVNYQHNNIAEVSSLAG 212
Cdd:COG4886    32 LLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSN 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 213 LPNLVFLDLYSNKVNRV-LDMHHVPLLRVLMLGKNCLTCV-EGLEPLARLDVLDLHNNEVSSL-RGFASLPSLRILNLAG 289
Cdd:COG4886   112 LTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSN 191

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1931045932 290 NKVASLAPGLHQLTSLTELNLRRNSIRAVDGGKAGRTlvppALQRLFLSHNcieRLDDLSDLRTLTNLKELTVEGN 365
Cdd:COG4886   192 NQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLT----NLETLDLSNN---QLTDLPELGNLTNLEELDLSNN 260
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
133-365 1.13e-22

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 100.78  E-value: 1.13e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 133 TAKPAKSADIVESDRDGVLVTRRSGQLYVERTKQAKDAQPERLNLDRRHLDSCCLILNDERLRLVNYQHNNIAEVSSLAG 212
Cdd:COG4886    32 LLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSN 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 213 LPNLVFLDLYSNKVNRV-LDMHHVPLLRVLMLGKNCLTCV-EGLEPLARLDVLDLHNNEVSSL-RGFASLPSLRILNLAG 289
Cdd:COG4886   112 LTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSN 191

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1931045932 290 NKVASLAPGLHQLTSLTELNLRRNSIRAVDGGKAGRTlvppALQRLFLSHNcieRLDDLSDLRTLTNLKELTVEGN 365
Cdd:COG4886   192 NQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLT----NLETLDLSNN---QLTDLPELGNLTNLEELDLSNN 260
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 200-405 7.27e-22

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 94.08  E-value: 7.27e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 200 QHNNIAEVSSLAGLPNLVFLDLYSNKVNRVLDMHHVPLLRVLMLGKNCLTCVEGLEPLARLDVLDLHNNEVSSLRGFASL 279
Cdd:cd21340    10 NDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGLENL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 280 PSLRILNLAGNKvasLAPGlHQLT-----------SLTELNLRRNSIRAVDGgkagrtLVP-PALQRLFLSHNCIERLDD 347
Cdd:cd21340    90 TNLEELHIENQR---LPPG-EKLTfdprslaalsnSLRVLNISGNNIDSLEP------LAPlRNLEQLDASNNQISDLEE 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1931045932 348 LSD-LRTLTNLKELTVEGNvELCADRRrsisLRGAVddgvttaILqLCPGLRVLDAVNI 405
Cdd:cd21340   160 LLDlLSSWPSLRELDLTGN-PVCKKPK----YRDKI-------IL-ASKSLEVLDGKEI 205
LRR_8 pfam13855
Leucine rich repeat;
259-315 5.92e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.45  E-value: 5.92e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 259 RLDVLDLHNNEVSSLRG--FASLPSLRILNLAGNKVASLAPG-LHQLTSLTELNLRRNSI 315
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
128-345 1.67e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 51.24  E-value: 1.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 128 ASAAKTAKPAKSADIVESDRDGVLVTRRSG--QLYVERTKQAKDAQPERLNLDRRHLDS---------CCLIL-NDERLR 195
Cdd:PRK15370  134 ASSASGSKDAVNYELIWSEWVKEAPAKEAAnrEEAVQRMRDCLKNNKTELRLKILGLTTipacipeqiTTLILdNNELKS 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 196 LVNYQHNNIAEVS----SLAGLP-----NLVFLDLysnKVNRVLDM-HHVP-LLRVLMLGKNCLTCVEGLEPlARLDVLD 264
Cdd:PRK15370  214 LPENLQGNIKTLYansnQLTSIPatlpdTIQEMEL---SINRITELpERLPsALQSLDLFHNKISCLPENLP-EELRYLS 289

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 265 LHNNEVSSLRgfASLPS-LRILNLAGNKV----ASLAPGL-------HQLTSLTE--------LNLRRNSIRAVDggkag 324
Cdd:PRK15370  290 VYDNSIRTLP--AHLPSgITHLNVQSNSLtalpETLPPGLktleageNALTSLPAslppelqvLDVSKNQITVLP----- 362

                         250       260
                  ....*....|....*....|.
gi 1931045932 325 RTLvPPALQRLFLSHNCIERL 345
Cdd:PRK15370  363 ETL-PPTITTLDVSRNALTNL 382
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
133-365 1.13e-22

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 100.78  E-value: 1.13e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 133 TAKPAKSADIVESDRDGVLVTRRSGQLYVERTKQAKDAQPERLNLDRRHLDSCCLILNDERLRLVNYQHNNIAEVSSLAG 212
Cdd:COG4886    32 LLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSN 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 213 LPNLVFLDLYSNKVNRV-LDMHHVPLLRVLMLGKNCLTCV-EGLEPLARLDVLDLHNNEVSSL-RGFASLPSLRILNLAG 289
Cdd:COG4886   112 LTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSN 191

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1931045932 290 NKVASLAPGLHQLTSLTELNLRRNSIRAVDGGKAGRTlvppALQRLFLSHNcieRLDDLSDLRTLTNLKELTVEGN 365
Cdd:COG4886   192 NQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLT----NLETLDLSNN---QLTDLPELGNLTNLEELDLSNN 260
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 200-405 7.27e-22

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 94.08  E-value: 7.27e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 200 QHNNIAEVSSLAGLPNLVFLDLYSNKVNRVLDMHHVPLLRVLMLGKNCLTCVEGLEPLARLDVLDLHNNEVSSLRGFASL 279
Cdd:cd21340    10 NDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGLENL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 280 PSLRILNLAGNKvasLAPGlHQLT-----------SLTELNLRRNSIRAVDGgkagrtLVP-PALQRLFLSHNCIERLDD 347
Cdd:cd21340    90 TNLEELHIENQR---LPPG-EKLTfdprslaalsnSLRVLNISGNNIDSLEP------LAPlRNLEQLDASNNQISDLEE 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1931045932 348 LSD-LRTLTNLKELTVEGNvELCADRRrsisLRGAVddgvttaILqLCPGLRVLDAVNI 405
Cdd:cd21340   160 LLDlLSSWPSLRELDLTGN-PVCKKPK----YRDKI-------IL-ASKSLEVLDGKEI 205
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
194-368 3.73e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 89.99  E-value: 3.73e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 194 LRLVNYQHNNIAEVS-SLAGLPNLVFLDLYSNKVNRV-LDMHHVPLLRVLMLGKNCLTCV-EGLEPLARLDVLDLHNNEV 270
Cdd:COG4886   161 LKSLDLSNNQLTDLPeELGNLTNLKELDLSNNQITDLpEPLGNLTNLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQL 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 271 SSLRGFASLPSLRILNLAGNKVASLaPGLHQLTSLTELNLRRNSIRAVDGGKAGRTLVPPALQRLFLSHNCIERLDDLSD 350
Cdd:COG4886   241 TDLPELGNLTNLEELDLSNNQLTDL-PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLL 319

                         170
                  ....*....|....*...
gi 1931045932 351 LRTLTNLKELTVEGNVEL 368
Cdd:COG4886   320 LTTLLLLLLLLKGLLVTL 337
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
186-365 3.98e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.58  E-value: 3.98e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 186 CLILNDERLRLVNYQHNNIAEVSSLAGLPNLVFLDLYSNKVNRVLDMHHVPLLRVLMLGKNCLTCVEGLEPLARLDVLDL 265
Cdd:COG4886    24 LILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 266 HNNEvsslrGFASLPSLRILNLAGNKVASLAPGLHQLTSLTELNLRRNSIRAVDGGKAGRTlvppALQRLFLSHNCIERL 345
Cdd:COG4886   104 SGNE-----ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLT----NLKSLDLSNNQLTDL 174

                         170       180
                  ....*....|....*....|
gi 1931045932 346 DdlSDLRTLTNLKELTVEGN 365
Cdd:COG4886   175 P--EELGNLTNLKELDLSNN 192
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
188-365 5.93e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 71.12  E-value: 5.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 188 ILNDERLRLVNYQHNNIAEVS-SLAGLPNLVFLDLYSNKVNRV-LDMHHVPLLRVLMLGKNCLTCVEGLEPLARLDVLDL 265
Cdd:COG4886   178 LGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 266 HNNEVSSLRGFASLPSLRILNLAGNKVASLA----PGLHQLTSLTELNLRRNSIRAVDGGKAGRTLVPPALQRLFLSHNC 341
Cdd:COG4886   258 SNNQLTDLPPLANLTNLKTLDLSNNQLTDLKlkelELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTL 337

                         170       180
                  ....*....|....*....|....
gi 1931045932 342 IERLDDLSDLRTLTNLKELTVEGN 365
Cdd:COG4886   338 TTLALSLSLLALLTLLLLLNLLSL 361
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 257-363 2.93e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 66.35  E-value: 2.93e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 257 LARLDVLDLHNNEVSSLRGFASLPSLRILNLAGNKVASLaPGLHQLTSLTELNLRRNSIRAVDGgkagrtLVP-PALQRL 335
Cdd:cd21340     1 LKRITHLYLNDKNITKIDNLSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIEN------LENlVNLKKL 73

                          90       100
                  ....*....|....*....|....*...
gi 1931045932 336 FLSHNCIERlddLSDLRTLTNLKELTVE 363
Cdd:cd21340    74 YLGGNRISV---VEGLENLTNLEELHIE 98
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 233-365 4.02e-08

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 55.05  E-value: 4.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 233 HHVPLLRVLMLGKNCLTcVEGLEPLA-------RLDVLDLHNNEVSS------LRGFASLPSLRILNLAGNK-----VAS 294
Cdd:cd00116   134 DLPPALEKLVLGRNRLE-GASCEALAkalranrDLKELNLANNGIGDagiralAEGLKANCNLEVLDLNNNGltdegASA 212

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1931045932 295 LAPGLHQLTSLTELNLRRNSIRAVDGGKAGRTLVPPA--LQRLFLSHNCIERLDDLSDLRTLTN---LKELTVEGN 365
Cdd:cd00116   213 LAETLASLKSLEVLNLGDNNLTDAGAAALASALLSPNisLLTLSLSCNDITDDGAKDLAEVLAEkesLLELDLRGN 288
LRR_8 pfam13855
Leucine rich repeat;
259-315 5.92e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.45  E-value: 5.92e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 259 RLDVLDLHNNEVSSLRG--FASLPSLRILNLAGNKVASLAPG-LHQLTSLTELNLRRNSI 315
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
128-345 1.67e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 51.24  E-value: 1.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 128 ASAAKTAKPAKSADIVESDRDGVLVTRRSG--QLYVERTKQAKDAQPERLNLDRRHLDS---------CCLIL-NDERLR 195
Cdd:PRK15370  134 ASSASGSKDAVNYELIWSEWVKEAPAKEAAnrEEAVQRMRDCLKNNKTELRLKILGLTTipacipeqiTTLILdNNELKS 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 196 LVNYQHNNIAEVS----SLAGLP-----NLVFLDLysnKVNRVLDM-HHVP-LLRVLMLGKNCLTCVEGLEPlARLDVLD 264
Cdd:PRK15370  214 LPENLQGNIKTLYansnQLTSIPatlpdTIQEMEL---SINRITELpERLPsALQSLDLFHNKISCLPENLP-EELRYLS 289

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 265 LHNNEVSSLRgfASLPS-LRILNLAGNKV----ASLAPGL-------HQLTSLTE--------LNLRRNSIRAVDggkag 324
Cdd:PRK15370  290 VYDNSIRTLP--AHLPSgITHLNVQSNSLtalpETLPPGLktleageNALTSLPAslppelqvLDVSKNQITVLP----- 362

                         250       260
                  ....*....|....*....|.
gi 1931045932 325 RTLvPPALQRLFLSHNCIERL 345
Cdd:PRK15370  363 ETL-PPTITTLDVSRNALTNL 382
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 259-309 3.34e-06

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 44.16  E-value: 3.34e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1931045932 259 RLDVLDLHNNEVSSLRGFASLPSLRILNLAGNkvaslapglHQLTSLTELN 309
Cdd:pfam12799   2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGN---------NKITDLSDLA 43
LRR_8 pfam13855
Leucine rich repeat;
280-340 4.34e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.44  E-value: 4.34e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1931045932 280 PSLRILNLAGNKVASLAPG-LHQLTSLTELNLRRNSIRAVDGGkagrTLVP-PALQRLFLSHN 340
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLSPG----AFSGlPSLRYLDLSGN 59
LRR_8 pfam13855
Leucine rich repeat;
303-365 3.00e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.74  E-value: 3.00e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1931045932 303 TSLTELNLRRNSIRAVDGGkAGRTLvpPALQRLFLSHNCIERLDDlSDLRTLTNLKELTVEGN 365
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDG-AFKGL--SNLKVLDLSNNLLTTLSP-GAFSGLPSLRYLDLSGN 59
LRR_8 pfam13855
Leucine rich repeat;
236-292 4.23e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.36  E-value: 4.23e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1931045932 236 PLLRVLMLGKNCLTcveGLEP-----LARLDVLDLHNNEVSSL--RGFASLPSLRILNLAGNKV 292
Cdd:pfam13855   1 PNLRSLDLSNNRLT---SLDDgafkgLSNLKVLDLSNNLLTTLspGAFSGLPSLRYLDLSGNRL 61
LRR_9 pfam14580
Leucine-rich repeat;
257-365 5.83e-05

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 43.98  E-value: 5.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 257 LARLDVLDLHNNEVSSLRGFASLPSLRILNLAGNKVASLAPGLHQltsltelnlrrnsiravdggkagrtlVPPALQRLF 336
Cdd:pfam14580  41 LDQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIGEGLGE--------------------------ALPNLTELI 94

                          90       100
                  ....*....|....*....|....*....
gi 1931045932 337 LSHNCIERLDDLSDLRTLTNLKELTVEGN 365
Cdd:pfam14580  95 LTNNNLQELGDLDPLASLKKLTFLSLLRN 123
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 252-369 1.10e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 44.78  E-value: 1.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 252 EGLEPLARLDVLDLHNNEVSSlRGFASL-------PSLRILNLAGNKV-----ASLAPGLHQLTSLTELNLRRNSIravd 319
Cdd:COG5238   230 EALKGNKSLTTLDLSNNQIGD-EGVIALaealknnTTVETLYLSGNQIgaegaIALAKALQGNTTLTSLDLSVNRI---- 304

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1931045932 320 gGKAGRTLVPPALQR------LFLSHN------CIERLDDLSDLRTLTNLK----ELTVEGNVELC 369
Cdd:COG5238   305 -GDEGAIALAEGLQGnktlhtLNLAYNgigaqgAIALAKALQENTTLHSLDlsdnQIGDEGAIALA 369
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 280-313 2.05e-04

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 39.15  E-value: 2.05e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1931045932 280 PSLRILNLAGNKVASLaPGLHQLTSLTELNLRRN 313
Cdd:pfam12799   1 PNLEVLDLSNNQITDI-PPLAKLPNLETLDLSGN 33
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 210-337 7.08e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.96  E-value: 7.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 210 LAGLPNLVFLDLYSNKVNRvldmhhvpllrvlmlgKNCLTCVEGLEPLARLDVLDLHNNEVSSlRGFASL--------PS 281
Cdd:cd00116   189 LKANCNLEVLDLNNNGLTD----------------EGASALAETLASLKSLEVLNLGDNNLTD-AGAAALasallspnIS 251

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1931045932 282 LRILNLAGNK-----VASLAPGLHQLTSLTELNLRRNSIRAVDGGKAGRTLVPPALQRLFL 337
Cdd:cd00116   252 LLTLSLSCNDitddgAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAESLLEPGNELESL 312
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 236-278 7.51e-04

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 37.61  E-value: 7.51e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1931045932 236 PLLRVLMLGKNCLTCVEGLEPLARLDVLDL-HNNEVSSLRGFAS 278
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLsGNNKITDLSDLAN 44
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 330-368 1.19e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 36.84  E-value: 1.19e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1931045932 330 PALQRLFLSHNCIErldDLSDLRTLTNLKELTVEGNVEL 368
Cdd:pfam12799   1 PNLEVLDLSNNQIT---DIPPLAKLPNLETLDLSGNNKI 36
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 234-323 2.94e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 40.16  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 234 HVPLLRVLMLGKNCLTCvEGLEPLA-------RLDVLDLHNNEVSS--LRGFASL----PSLRILNLAGNK-----VASL 295
Cdd:COG5238   234 GNKSLTTLDLSNNQIGD-EGVIALAealknntTVETLYLSGNQIGAegAIALAKAlqgnTTLTSLDLSVNRigdegAIAL 312

                          90       100
                  ....*....|....*....|....*...
gi 1931045932 296 APGLHQLTSLTELNLRRNSIRAvDGGKA 323
Cdd:COG5238   313 AEGLQGNKTLHTLNLAYNGIGA-QGAIA 339
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 193-224 3.93e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 35.30  E-value: 3.93e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1931045932 193 RLRLVNYQHNNIAEVSSLAGLPNLVFLDLYSN 224
Cdd:pfam12799   2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGN 33
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 198-363 4.76e-03

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 39.86  E-value: 4.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932  198 NYQHNNIAEVSSLAGLPNLVfldLYSNKVNRvLDMHHVPLLRVLMLGKNcltcvegLEPLARLDVldlhnNEVSSLRGFA 277
Cdd:PLN03210   658 NLETLKLSDCSSLVELPSSI---QYLNKLED-LDMSRCENLEILPTGIN-------LKSLYRLNL-----SGCSRLKSFP 721

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932  278 SLPS-LRILNLAGNKVASLAPGLHqLTSLTELNLRRNSIRAVDGGKAGRT----LVPPALQRLFLSHncIERLDDL-SDL 351
Cdd:PLN03210   722 DISTnISWLDLDETAIEEFPSNLR-LENLDELILCEMKSEKLWERVQPLTplmtMLSPSLTRLFLSD--IPSLVELpSSI 798

                          170
                   ....*....|..
gi 1931045932  352 RTLTNLKELTVE 363
Cdd:PLN03210   799 QNLHKLEHLEIE 810
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 208-315 6.75e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.45  E-value: 6.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 208 SSLAGLPNLVFLDLYSNKV-----NRVLDMHHvplLRVLMLGKNCLT--CVEGLEPLARLDVLDLHNNEVSSL--RGFAS 278
Cdd:PLN00113  254 SSLGNLKNLQYLFLYQNKLsgpipPSIFSLQK---LISLDLSDNSLSgeIPELVIQLQNLEILHLFSNNFTGKipVALTS 330

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1931045932 279 LPSLRILNLAGNKVASLAP-GLHQLTSLTELNLRRNSI 315
Cdd:PLN00113  331 LPRLQVLQLWSNKFSGEIPkNLGKHNNLTVLDLSTNNL 368
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 194-340 8.00e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.45  E-value: 8.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 194 LRLVNYQHNNIAEVSSLAGLPNLVFLDLYSNKVNRVL--DMHHVPLLRVLMLGKNCLT--CVEGLEPLARLDVLDLHNNE 269
Cdd:PLN00113  120 LRYLNLSNNNFTGSIPRGSIPNLETLDLSNNMLSGEIpnDIGSFSSLKVLDLGGNVLVgkIPNSLTNLTSLEFLTLASNQ 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 270 VSSL--RGFASLPSLRILNLAGNKVASLAP-GLHQLTSLTELNLRRNSIRAVdggkagrtlVPPA------LQRLFLSHN 340
Cdd:PLN00113  200 LVGQipRELGQMKSLKWIYLGYNNLSGEIPyEIGGLTSLNHLDLVYNNLTGP---------IPSSlgnlknLQYLFLYQN 270
LRR_9 pfam14580
Leucine-rich repeat;
197-286 9.22e-03

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 37.44  E-value: 9.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931045932 197 VNYQHNNIAEVSSLAGLPNLVFLDLYSNKVNRV---LDmHHVPLLRVLMLGKNCLTCVEGLEPLA---RLDVLDLHNNEV 270
Cdd:pfam14580  47 IDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIgegLG-EALPNLTELILTNNNLQELGDLDPLAslkKLTFLSLLRNPV 125

                          90       100
                  ....*....|....*....|.
gi 1931045932 271 SS-----LRGFASLPSLRILN 286
Cdd:pfam14580 126 TNkphyrLYVIYKVPQLRLLD 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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