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Conserved domains on  [gi|1916859093|gb|QOL00851|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Phyllomimus sinicus]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 3.18e-21

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 79.81  E-value: 3.18e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916859093  4 ILNWLSLIFVMLGGIWVFCSNRKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEIYFLMIFLSFCVCEGALGLSILVLLIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1916859093 84 THGNDYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 3.18e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 79.81  E-value: 3.18e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916859093  4 ILNWLSLIFVMLGGIWVFCSNRKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEIYFLMIFLSFCVCEGALGLSILVLLIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1916859093 84 THGNDYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
25-98 1.24e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 50.26  E-value: 1.24e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1916859093 25 RKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEI--YFLMIFLSFCVCEGALGLSILVLLIRTHGNDYFQSFSILQC 98
Cdd:pfam00420 20 RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 3.18e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 79.81  E-value: 3.18e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916859093  4 ILNWLSLIFVMLGGIWVFCSNRKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEIYFLMIFLSFCVCEGALGLSILVLLIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1916859093 84 THGNDYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 3-98 8.32e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 58.70  E-value: 8.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916859093  3 MILNWLSLIFVMLGGIWVFCSNRKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEIYFLMIFLSFCVCEGALGLSILVLLI 82
Cdd:MTH00149   2 MFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLI 81

                         90
                 ....*....|....*.
gi 1916859093 83 RTHGNDYFQSFSILQC 98
Cdd:MTH00149  82 RLHGNDYVSSLSSLKF 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 8-98 3.21e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 57.29  E-value: 3.21e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916859093  8 LSLIFVMLGGIWVFCSNRKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEIYFLMIFLSFCVCEGALGLSILVLLIRTHGN 87
Cdd:MTH00188   7 LVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHGS 86

                         90
                 ....*....|.
gi 1916859093 88 DYFQSFSILQC 98
Cdd:MTH00188  87 DYVSSLNLIKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 24-98 1.78e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 55.24  E-value: 1.78e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1916859093 24 NRKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEIYFLM--IFLSFCVCEGALGLSILVLLIRTHGNDYFQSFSILQC 98
Cdd:MTH00125  22 HRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALLVATTRTHGSDHLKNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 24-98 1.59e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 52.66  E-value: 1.59e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1916859093 24 NRKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEIYFL--MIFLSFCVCEGALGLSILVLLIRTHGNDYFQSFSILQC 98
Cdd:MTH00126  22 HRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAapMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 25-98 5.35e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 51.53  E-value: 5.35e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1916859093 25 RKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEIYFL--MIFLSFCVCEGALGLSILVLLIRTHGNDYFQSFSILQC 98
Cdd:MTH00067  23 RTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSlpMFMLTFSACEASTGLALMVATTRTHGTDHLKNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
25-98 1.24e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 50.26  E-value: 1.24e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1916859093 25 RKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEI--YFLMIFLSFCVCEGALGLSILVLLIRTHGNDYFQSFSILQC 98
Cdd:pfam00420 20 RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 25-98 4.17e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 44.15  E-value: 4.17e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1916859093 25 RKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEIYFLM--IFLSFCVCEGALGLSILVLLIRTHGNDYFQSFSILQC 98
Cdd:MTH00107  23 RSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMpiILLVFAACEAAVGLALLVMVSNTYGTDYVQNLNLLQC 98
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 20-98 4.63e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 43.97  E-value: 4.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916859093 20 VFCSNRKHLLTMLLSLEFMVLGVFLFLFVYFGFFNN-EIYFLMIFLSFCVCEGALGLSILVLLIRTHGNDYFQSFSILQC 98
Cdd:MTH00013  18 NLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFANQvNGMLAIVLLTFGACEASLGLSLLVLMTRSYGNDMLKSLTSNKC 97
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 7-96 5.10e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 43.78  E-value: 5.10e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916859093  7 WLSLIFVMLGGIWVFCSNRKHLLTMLLSLEFMVLGVFLFLFVYF--GFFNNEIYFLMIFLSFCVCEGALGLSILVLLIRT 84
Cdd:MTH00181   2 MFVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSllSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRT 81

                         90
                 ....*....|..
gi 1916859093 85 HGNDYFQSFSIL 96
Cdd:MTH00181  82 HGSDHLLKFNLL 93
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 3-97 5.18e-06

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 41.06  E-value: 5.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916859093  3 MILNWLSLIFVMLGGIWVFCSNRKHLLTMLLSLEFMVLGVFLFLFVYFGFFNNEIY--FLMIFLSFCVCEGALGLSILVL 80
Cdd:MTH00043   1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVL 80

                         90
                 ....*....|....*..
gi 1916859093 81 LIRTHGNDYFQSFSILQ 97
Cdd:MTH00043  81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00180
NADH dehydrogenase subunit 4L; Provisional
 11-97 5.88e-03

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177231  Cd Length: 99  Bit Score: 33.08  E-value: 5.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916859093 11 IFVMLGGIWVFCSNRKHLLTMLLSLEFMVLGVFLFLFVYFGFFNN---EIYFLMIfLSFCVCEGALGLSILVLLIRTHGN 87
Cdd:MTH00180  10 IILFILGVLGIVLNRSNLIIMLMSIELMLLAISLLFLINSVAIDNligQIFTIMI-LTVAAAESAIGLAILVAYYRIRGT 88

                         90
                 ....*....|
gi 1916859093 88 DYFQSFSILQ 97
Cdd:MTH00180  89 IAVKSLNLLR 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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