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Conserved domains on  [gi|1916858890|gb|QOL00656|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Leuconemacris litangensis]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 4.73e-22

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 81.74  E-value: 4.73e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  3 MFSIFTSLLIYFTGVYVFSSKRKHLLMVLLSLEYIVLSLFLMIMIFLMEFDYDYFFPVVFLVFSVCEGALGFLILVSMIR 82
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1916858890 83 SHGNDFFNS 91
Cdd:MTH00162  81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 4.73e-22

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 81.74  E-value: 4.73e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  3 MFSIFTSLLIYFTGVYVFSSKRKHLLMVLLSLEYIVLSLFLMIMIFLMEFDYDYFFPVVFLVFSVCEGALGFLILVSMIR 82
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1916858890 83 SHGNDFFNS 91
Cdd:MTH00162  81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-94 5.19e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 43.71  E-value: 5.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  4 FSIFTSLLIYFTGVYVFSSkRKHLLMVLLSLEYIVLSLFLMIMIFLMEFDYDY--FFPVVFLVFSVCEGALGFLILVSMI 81
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|...
gi 1916858890 82 RSHGNDFFNSFWL 94
Cdd:pfam00420 80 RTHGTDDVDSLNL 92
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 4.73e-22

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 81.74  E-value: 4.73e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  3 MFSIFTSLLIYFTGVYVFSSKRKHLLMVLLSLEYIVLSLFLMIMIFLMEFDYDYFFPVVFLVFSVCEGALGFLILVSMIR 82
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1916858890 83 SHGNDFFNS 91
Cdd:MTH00162  81 SHGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 6-97 1.54e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 58.06  E-value: 1.54e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  6 IFTSLLIYFTGVYVFSSKRKHLLMVLLSLEYIVLSLFLMIMIFLMEFDYDYFFPVVFLVFSVCEGALGFLILVSMIRSHG 85
Cdd:MTH00188   6 ILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHG 85

                         90
                 ....*....|..
gi 1916858890 86 NDFFNSFWLSLC 97
Cdd:MTH00188  86 SDYVSSLNLIKC 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 1-92 5.53e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 51.38  E-value: 5.53e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  1 MYMFSIFTSLLIYFTGVYVFSSKRKHLLMVLLSLEYIVLSLFLMIMIFLMEFDYDYFFPVVFLVFSVCEGALGFLILVSM 80
Cdd:MTH00149   1 SMFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSL 80

                         90
                 ....*....|..
gi 1916858890 81 IRSHGNDFFNSF 92
Cdd:MTH00149  81 IRLHGNDYVSSL 92
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 2-97 8.01e-10

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 50.91  E-value: 8.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  2 YMFSIFTSLLIYFTGVYVFSSKRKHLLMVLLSLEYIVLSLFLMIMIFLM-EFDYDYFFPVVFLVFSVCEGALGFLILVSM 80
Cdd:MTH00013   1 MMSPLFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMfANQVNGMLAIVLLTFGACEASLGLSLLVLM 80

                         90
                 ....*....|....*..
gi 1916858890 81 IRSHGNDFFNSFWLSLC 97
Cdd:MTH00013  81 TRSYGNDMLKSLTSNKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 4-97 1.49e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 50.23  E-value: 1.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  4 FSIFTSLLIYFTGvyvFSSKRKHLLMVLLSLEYIVLSLFLMIMIFLMEFDYDYFF--PVVFLVFSVCEGALGFLILVSMI 81
Cdd:MTH00125   6 FSLYTAFMLSLLG---LSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTpmPIILLTFSACEAGTGLALLVATT 82

                         90
                 ....*....|....*.
gi 1916858890 82 RSHGNDFFNSFWLSLC 97
Cdd:MTH00125  83 RTHGSDHLKNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 24-97 2.41e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 47.27  E-value: 2.41e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1916858890 24 RKHLLMVLLSLEYIVLSLFLMIMIFLMEFDYDYFF--PVVFLVFSVCEGALGFLILVSMIRSHGNDFFNSFWLSLC 97
Cdd:MTH00126  23 RTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSaaPMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-97 1.41e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 45.36  E-value: 1.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  1 MYMFSIFTSLLIYFTGvyvFSSKRKHLLMVLLSLEYIVLSLFLMIMIFLMEFDYDYFF--PVVFLVFSVCEGALGFLILV 78
Cdd:MTH00067   3 PTYFTFYSAFLLGLMG---LAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFslPMFMLTFSACEASTGLALMV 79

                         90
                 ....*....|....*....
gi 1916858890 79 SMIRSHGNDFFNSFWLSLC 97
Cdd:MTH00067  80 ATTRTHGTDHLKNLNLLQC 98
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 4-88 4.14e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 44.15  E-value: 4.14e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  4 FSIFTSLLIYFTGVYVFsskRKHLLMVLLSLEYIVLSLFLM--IMIFLMEFDYDYFFPVVFLVFSVCEGALGFLILVSMI 81
Cdd:MTH00107   6 MNIMLAFTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMatLTILNTHFTLASMMPIILLVFAACEAAVGLALLVMVS 82


                 ....*..
gi 1916858890 82 RSHGNDF 88
Cdd:MTH00107  83 NTYGTDY 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-94 5.19e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 43.71  E-value: 5.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  4 FSIFTSLLIYFTGVYVFSSkRKHLLMVLLSLEYIVLSLFLMIMIFLMEFDYDY--FFPVVFLVFSVCEGALGFLILVSMI 81
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|...
gi 1916858890 82 RSHGNDFFNSFWL 94
Cdd:pfam00420 80 RTHGTDDVDSLNL 92
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 7-95 1.44e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 39.93  E-value: 1.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  7 FTSLLIYFTGVYVFSSKRKHLLMVLLSLEYIVLSLFLMIMIFLMEFDY--DYFFPVVFLVFSVCEGALGFLILVSMIRSH 84
Cdd:MTH00181   3 FVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSssMLMFGLILLTFSACEAVLGLSLLVATNRTH 82

                         90
                 ....*....|.
gi 1916858890 85 GNDFFNSFWLS 95
Cdd:MTH00181  83 GSDHLLKFNLL 93
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 3-91 3.12e-04

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 36.43  E-value: 3.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1916858890  3 MFSIFTSLLIYFTGVYVFSSKRKHLLMVLLSLEYIVLSLFLMIMIFLMEFDYDYF--FPVVFLVFSVCEGALGFLILVSM 80
Cdd:MTH00043   2 NIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVLL 81

                         90
                 ....*....|.
gi 1916858890 81 IRSHGNDFFNS 91
Cdd:MTH00043  82 SRNHNSDLVAS 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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