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Conserved domains on  [gi|1914782031|ref|NP_001374580|]
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focal adhesion kinase 1 isoform 69 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FERM_N_2 super family cl39453
FERM N-terminal domain; This entry represents the FERM N-terminal domain found in focal ...
 35-121 2.17e-45

FERM N-terminal domain; This entry represents the FERM N-terminal domain found in focal adhesion kinases.


The actual alignment was detected with superfamily member pfam18038:

Pssm-ID: 436229  Cd Length: 99  Bit Score: 142.21  E-value: 2.17e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914782031  35 RVLKVFHYFESNSEPTtWASIIRHGDATDVRGIIQKI---VDSHKV-KHVACYGFRLSHLRSEEVHWLHVDMGVSSVREK 110
Cdd:pfam18038   1 RILKVCHYSESNNEGK-WFKLIRCGDATDVRGIIQKIlssGRIGPViRHVSCYGLRLKHLKSDEVHWLHPDMTVSEVREK 79

                          90
                  ....*....|.
gi 1914782031 111 YELAHPPEEWK 121
Cdd:pfam18038  80 YEQQHPEAEWR 90
 
Name Accession Description Interval E-value
FERM_N_2 pfam18038
FERM N-terminal domain; This entry represents the FERM N-terminal domain found in focal ...
 35-121 2.17e-45

FERM N-terminal domain; This entry represents the FERM N-terminal domain found in focal adhesion kinases.


Pssm-ID: 436229  Cd Length: 99  Bit Score: 142.21  E-value: 2.17e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914782031  35 RVLKVFHYFESNSEPTtWASIIRHGDATDVRGIIQKI---VDSHKV-KHVACYGFRLSHLRSEEVHWLHVDMGVSSVREK 110
Cdd:pfam18038   1 RILKVCHYSESNNEGK-WFKLIRCGDATDVRGIIQKIlssGRIGPViRHVSCYGLRLKHLKSDEVHWLHPDMTVSEVREK 79

                          90
                  ....*....|.
gi 1914782031 111 YELAHPPEEWK 121
Cdd:pfam18038  80 YEQQHPEAEWR 90
 
Name Accession Description Interval E-value
FERM_N_2 pfam18038
FERM N-terminal domain; This entry represents the FERM N-terminal domain found in focal ...
 35-121 2.17e-45

FERM N-terminal domain; This entry represents the FERM N-terminal domain found in focal adhesion kinases.


Pssm-ID: 436229  Cd Length: 99  Bit Score: 142.21  E-value: 2.17e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1914782031  35 RVLKVFHYFESNSEPTtWASIIRHGDATDVRGIIQKI---VDSHKV-KHVACYGFRLSHLRSEEVHWLHVDMGVSSVREK 110
Cdd:pfam18038   1 RILKVCHYSESNNEGK-WFKLIRCGDATDVRGIIQKIlssGRIGPViRHVSCYGLRLKHLKSDEVHWLHPDMTVSEVREK 79

                          90
                  ....*....|.
gi 1914782031 111 YELAHPPEEWK 121
Cdd:pfam18038  80 YEQQHPEAEWR 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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