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Conserved domains on  [gi|1907205178|ref|XP_036017936|]
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zinc finger MYM-type protein 3 isoform X8 [Mus musculus]

Protein Classification

zf-FCS and DUF3504 domain-containing protein( domain architecture ID 13363461)

protein containing domains PHA03307, TRASH, zf-FCS, and DUF3504

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1177-1344 6.23e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


:

Pssm-ID: 463430  Cd Length: 162  Bit Score: 268.37  E-value: 6.23e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178 1177 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1256
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178 1257 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1333
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 1907205178 1334 MLESMLNRILA 1344
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 2-304 6.30e-09

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 60.96  E-value: 6.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178    2 DPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPGGVLDGA 77
Cdd:PHA03307    66 EPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPG 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178   78 TELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDSPIILES 155
Cdd:PHA03307   146 PPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASASSPAPA 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178  156 PHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPTAHPSLP 222
Cdd:PHA03307   224 PGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPSPSPSSP 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178  223 GDGLTGKEIEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLR-SSMAQRAG 301
Cdd:PHA03307   304 GSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRApSSPAASAG 383


                   ...
gi 1907205178  302 RSS 304
Cdd:PHA03307   384 RPT 386
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 493-532 4.59e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.37  E-value: 4.59e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  493 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 532
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 348-389 3.67e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 3.67e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1907205178  348 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 389
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 586-623 1.18e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.18e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  586 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 623
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 446-488 2.11e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.11e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907205178  446 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 488
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 674-710 2.69e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 2.69e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  674 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 710
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 715-751 1.94e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 1.94e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  715 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 751
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 541-578 8.74e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.12  E-value: 8.74e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  541 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 578
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 628-664 1.92e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.92e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  628 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 664
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
311-347 4.32e-03

metallochaperone-like domain;


:

Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.20  E-value: 4.32e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205178   311 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 347
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 404-440 4.85e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.85e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  404 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 440
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1177-1344 6.23e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 268.37  E-value: 6.23e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178 1177 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1256
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178 1257 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1333
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 1907205178 1334 MLESMLNRILA 1344
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-304 6.30e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 60.96  E-value: 6.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178    2 DPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPGGVLDGA 77
Cdd:PHA03307    66 EPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPG 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178   78 TELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDSPIILES 155
Cdd:PHA03307   146 PPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASASSPAPA 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178  156 PHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPTAHPSLP 222
Cdd:PHA03307   224 PGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPSPSPSSP 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178  223 GDGLTGKEIEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLR-SSMAQRAG 301
Cdd:PHA03307   304 GSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRApSSPAASAG 383


                   ...
gi 1907205178  302 RSS 304
Cdd:PHA03307   384 RPT 386
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 493-532 4.59e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.37  E-value: 4.59e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  493 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 532
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 348-389 3.67e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 3.67e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1907205178  348 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 389
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 586-623 1.18e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.18e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  586 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 623
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 446-488 2.11e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.11e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907205178  446 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 488
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 674-710 2.69e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 2.69e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  674 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 710
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
498-536 6.10e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 41.59  E-value: 6.10e-05
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205178   498 CVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQ 536
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 715-751 1.94e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 1.94e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  715 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 751
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
451-492 2.39e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 2.39e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 1907205178   451 CDQCGAYIYaRPGGlgPELLFHDGQQKRFCNTTCLGAYKKKN 492
Cdd:smart00746    1 CSFCGKDIY-NPGT--GIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
591-627 3.00e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 3.00e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205178   591 CHYCHSLFS--GKPEVLEWQDQVFQFCCRDCCEDFKRLR 627
Cdd:smart00746    1 CSFCGKDIYnpGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 541-578 8.74e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.12  E-value: 8.74e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  541 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 578
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
679-711 9.77e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.13  E-value: 9.77e-04
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1907205178   679 CTYCSQTCQRGVTE---QLDGSTWDFCSEDCKTKYL 711
Cdd:smart00746    1 CSFCGKDIYNPGTGimvVNDGKVYYFCSSKCLSKFK 36
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 628-664 1.92e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.92e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  628 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 664
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
311-347 4.32e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.20  E-value: 4.32e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205178   311 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 347
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 404-440 4.85e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.85e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  404 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 440
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
546-579 7.21e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 7.21e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1907205178   546 CSFCRRSLSDPCYYNKV--DRTVYQFCSPSCWTKFQ 579
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVvnDGKVYYFCSSKCLSKFK 36
TRASH smart00746
metallochaperone-like domain;
720-755 9.51e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 9.51e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205178   720 CHACKRQGKLLETIH---WRGQIRHFCNQQCLLRFYSQQ 755
Cdd:smart00746    1 CSFCGKDIYNPGTGImvvNDGKVYYFCSSKCLSKFKKKR 39
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1177-1344 6.23e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 268.37  E-value: 6.23e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178 1177 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1256
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178 1257 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1333
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 1907205178 1334 MLESMLNRILA 1344
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-304 6.30e-09

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 60.96  E-value: 6.30e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178    2 DPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPGGVLDGA 77
Cdd:PHA03307    66 EPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPG 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178   78 TELLGLGGLLYKAPSPPEVD--HGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGllEPLAPDSPIILES 155
Cdd:PHA03307   146 PPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISASASSPAPA 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178  156 PHIEEEIPPLATRRRGSP--------GQEEEHTQGQPQSPNAP-----PSPSVGETLGDGINSSQSKPGVCTPTAHPSLP 222
Cdd:PHA03307   224 PGRSAADDAGASSSDSSSsessgcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPSPSPSSP 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178  223 GDGLTGKEIEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLR-SSMAQRAG 301
Cdd:PHA03307   304 GSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRApSSPAASAG 383


                   ...
gi 1907205178  302 RSS 304
Cdd:PHA03307   384 RPT 386
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 33-304 2.38e-07

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 55.56  E-value: 2.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178   33 DLLESQTAPSRGWAPPGPSPSSGALDLLDTPSGLEKDPGGVLDG----ATELLGLGGLLYKAPSPPEVDHGPEGTLAWDS 108
Cdd:PHA03307     9 DLIEAAAEGGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAAvtvvAGAAACDRFEPPTGPPPGPGTEAPANESRSTP 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178  109 G--EQTLEPGPGCQTPEVMPPDPGAGASPPSPEGLLEPLAPDSPIILESPHIEEEIPPLATRRR----GSPGQEEEHTQG 182
Cdd:PHA03307    89 TwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPpaagASPAAVASDAAS 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178  183 QPQSpnAPPSPSVGETLGDGINSSQSKPGVCTPTAHPslPGDGLTGKEIEKPPERKRSERVRRAEPPKPEVVDSTESIPV 262
Cdd:PHA03307   169 SRQA--ALPLSSPEETARAPSSPPAEPPPSTPPAAAS--PRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSES 244

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1907205178  263 SDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSMAQRAGRSS 304
Cdd:PHA03307   245 SGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPAS 286
PHA03247 PHA03247
large tegument protein UL36; Provisional
 3-278 4.52e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 54.94  E-value: 4.52e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178    3 PSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPSRGWAPPGP-SPSSGALDLLDTPSGLEKDPGGVLDGATEll 81
Cdd:PHA03247  2763 TAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAvLAPAAALPPAASPAGPLPPPTSAQPTAPP-- 2840

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178   82 glggllyKAPSPPEVDHGPEGTLAwdSGEQTLEPGPGCQTPEV--MPPDPGA---GASPPSPEGLLEPLAPDSPIILESP 156
Cdd:PHA03247  2841 -------PPPGPPPPSLPLGGSVA--PGGDVRRRPPSRSPAAKpaAPARPPVrrlARPAVSRSTESFALPPDQPERPPQP 2911

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178  157 HIEEEIPPLATRRRGSPGQEEEHTQGQPQSPNAP---------PSPSVGET-LGDGINSSQSKPGVCTPTAHPSLPgdgl 226
Cdd:PHA03247  2912 QAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPttdpagagePSGAVPQPwLGALVPGRVAVPRFRVPQPAPSRE---- 2987

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907205178  227 TGKEIEKPPERKRSERVR--------RAEP-PKPEVVDSTESIPVSDEDSDA---MVDDPNDED 278
Cdd:PHA03247  2988 APASSTPPLTGHSLSRVSswasslalHEETdPPPVSLKQTLWPPDDTEDSDAdslFDSDSERSD 3051
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 493-532 4.59e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.37  E-value: 4.59e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  493 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 532
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 348-389 3.67e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 45.05  E-value: 3.67e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 1907205178  348 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 389
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 586-623 1.18e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.18e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  586 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 623
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 446-488 2.11e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.74  E-value: 2.11e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907205178  446 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 488
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 674-710 2.69e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 2.69e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  674 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 710
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
PHA03247 PHA03247
large tegument protein UL36; Provisional
 89-250 4.63e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 4.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178   89 KAPSPPEVDHGPEGTLAWDSGEqtlEPGPGCQTPEVMPPDPGAGASPPSP----EGLLE-----------PLAPDSPiil 153
Cdd:PHA03247  2487 RFPFAAGAAPDPGGGGPPDPDA---PPAPSRLAPAILPDEPVGEPVHPRMltwiRGLEElasddagdpppPLPPAAP--- 2560

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178  154 eSPHIEEEIPPlatrRRGSPGQEEEHTQGQPQSPNAPPSPSVGETLGDGINSS--QSKPGVCTPTAHPSLP--------G 223
Cdd:PHA03247  2561 -PAAPDRSVPP----PRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPrgPAPPSPLPPDTHAPDPpppspspaA 2635

                          170       180       190
                   ....*....|....*....|....*....|
gi 1907205178  224 DGLTGKEIEKPPERKRSER---VRRAEPPK 250
Cdd:PHA03247  2636 NEPDPHPPPTVPPPERPRDdpaPGRVSRPR 2665
TRASH smart00746
metallochaperone-like domain;
498-536 6.10e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 41.59  E-value: 6.10e-05
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205178   498 CVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQ 536
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 715-751 1.94e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 1.94e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  715 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 751
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
451-492 2.39e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 2.39e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 1907205178   451 CDQCGAYIYaRPGGlgPELLFHDGQQKRFCNTTCLGAYKKKN 492
Cdd:smart00746    1 CSFCGKDIY-NPGT--GIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
591-627 3.00e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 3.00e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205178   591 CHYCHSLFS--GKPEVLEWQDQVFQFCCRDCCEDFKRLR 627
Cdd:smart00746    1 CSFCGKDIYnpGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 99-288 8.52e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 8.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178   99 GPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPE----GLLEPLAPDSPIILESPHIEEEIPPLATRRRG-SP 173
Cdd:PRK07764   599 GPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEAsaapAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGaAP 678

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907205178  174 GQEEEHTQGQPQSPN---APPSPSVGETLGDGINSSQSKPGVCTPTAHPSLPGDGLTGKEIEKPPERKRSERVRRA---- 246
Cdd:PRK07764   679 AAPPPAPAPAAPAAPagaAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGApaqp 758

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1907205178  247 ---EPPKPEVVDSTESIPVSDEDSDAMVDDpnDEDFVPFRPRRSP 288
Cdd:PRK07764   759 pppPAPAPAAAPAAAPPPSPPSEEEEMAED--DAPSMDDEDRRDA 801
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 541-578 8.74e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.12  E-value: 8.74e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  541 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 578
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
679-711 9.77e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.13  E-value: 9.77e-04
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1907205178   679 CTYCSQTCQRGVTE---QLDGSTWDFCSEDCKTKYL 711
Cdd:smart00746    1 CSFCGKDIYNPGTGimvVNDGKVYYFCSSKCLSKFK 36
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 628-664 1.92e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.92e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  628 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 664
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
311-347 4.32e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.20  E-value: 4.32e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205178   311 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 347
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 404-440 4.85e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.85e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1907205178  404 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 440
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
546-579 7.21e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 7.21e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1907205178   546 CSFCRRSLSDPCYYNKV--DRTVYQFCSPSCWTKFQ 579
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVvnDGKVYYFCSSKCLSKFK 36
TRASH smart00746
metallochaperone-like domain;
720-755 9.51e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 9.51e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 1907205178   720 CHACKRQGKLLETIH---WRGQIRHFCNQQCLLRFYSQQ 755
Cdd:smart00746    1 CSFCGKDIYNPGTGImvvNDGKVYYFCSSKCLSKFKKKR 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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