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Conserved domains on  [gi|1901933189|dbj|GGR87372|]
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hypothetical protein GCM10008960_13240 [Deinococcus sedimenti]

Protein Classification

transposase family protein( domain architecture ID 1750106)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0015074|GO:0032196|GO:0003677

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS4_2 super family cl40564
IS4 family transposase;
48-145 3.98e-11

IS4 family transposase;


The actual alignment was detected with superfamily member NF033591:

Pssm-ID: 468100  Cd Length: 340  Bit Score: 59.60  E-value: 3.98e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1901933189  48 LYRARWSVECTFASLKVR-GFDLERTGITRPDRLERLFGLVVLA-WISCL--RVGVWLQAQVPVKV-KAHGRPAMSLVRY 122
Cdd:NF033591  230 LYARRMQIEELFRDLKSRyGFGLEDTRSRDPERLDILLLLAALAfIWAWLlgLAAEALGLHKHFQAnTVKGRRVLSLFRL 309

                          90       100
                  ....*....|....*....|...
gi 1901933189 123 GaerLCHALRWNLPELPALIRLL 145
Cdd:NF033591  310 G---LDVLRRPPLYLIRSLWLLE 329
 
Name Accession Description Interval E-value
transpos_IS4_2 NF033591
IS4 family transposase;
48-145 3.98e-11

IS4 family transposase;


Pssm-ID: 468100  Cd Length: 340  Bit Score: 59.60  E-value: 3.98e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1901933189  48 LYRARWSVECTFASLKVR-GFDLERTGITRPDRLERLFGLVVLA-WISCL--RVGVWLQAQVPVKV-KAHGRPAMSLVRY 122
Cdd:NF033591  230 LYARRMQIEELFRDLKSRyGFGLEDTRSRDPERLDILLLLAALAfIWAWLlgLAAEALGLHKHFQAnTVKGRRVLSLFRL 309

                          90       100
                  ....*....|....*....|...
gi 1901933189 123 GaerLCHALRWNLPELPALIRLL 145
Cdd:NF033591  310 G---LDVLRRPPLYLIRSLWLLE 329
DDE_Tnp_1 pfam01609
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 35-91 1.45e-05

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.


Pssm-ID: 376573 [Multi-domain]  Cd Length: 196  Bit Score: 43.00  E-value: 1.45e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1901933189  35 VVATDFSVWDTCVLYRARWSVECTFASLKvRGFDLERTGITRPDRLERLFGLVVLAW 91
Cdd:pfam01609 140 VNSTLLSAETLAELYRRRWQIERVFKWLK-RVFGLDRLRYRGLNAVEAELLLLALAY 195
 
Name Accession Description Interval E-value
transpos_IS4_2 NF033591
IS4 family transposase;
48-145 3.98e-11

IS4 family transposase;


Pssm-ID: 468100  Cd Length: 340  Bit Score: 59.60  E-value: 3.98e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1901933189  48 LYRARWSVECTFASLKVR-GFDLERTGITRPDRLERLFGLVVLA-WISCL--RVGVWLQAQVPVKV-KAHGRPAMSLVRY 122
Cdd:NF033591  230 LYARRMQIEELFRDLKSRyGFGLEDTRSRDPERLDILLLLAALAfIWAWLlgLAAEALGLHKHFQAnTVKGRRVLSLFRL 309

                          90       100
                  ....*....|....*....|...
gi 1901933189 123 GaerLCHALRWNLPELPALIRLL 145
Cdd:NF033591  310 G---LDVLRRPPLYLIRSLWLLE 329
DDE_Tnp_1 pfam01609
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 35-91 1.45e-05

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.


Pssm-ID: 376573 [Multi-domain]  Cd Length: 196  Bit Score: 43.00  E-value: 1.45e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1901933189  35 VVATDFSVWDTCVLYRARWSVECTFASLKvRGFDLERTGITRPDRLERLFGLVVLAW 91
Cdd:pfam01609 140 VNSTLLSAETLAELYRRRWQIERVFKWLK-RVFGLDRLRYRGLNAVEAELLLLALAY 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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