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Conserved domains on  [gi|1899807296|gb|QNQ16233|]
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NADH dehydrogenase subunit 4, partial (mitochondrion) [Proablepharus reginae]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-224 9.10e-133

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00124:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 457  Bit Score: 381.47  E-value: 9.10e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00124  234 ILLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAM 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00124  314 ILMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTI 393

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1899807296 161 IMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIMGP 224
Cdd:MTH00124  394 ILTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-224 9.10e-133

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 381.47  E-value: 9.10e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00124  234 ILLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAM 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00124  314 ILMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTI 393

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1899807296 161 IMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIMGP 224
Cdd:MTH00124  394 ILTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-225 4.12e-42

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 148.69  E-value: 4.12e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRIT-PMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:COG1008   250 VLLKMGGYGLLRFAlPLFPEASAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGA 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:COG1008   330 VLQMVSHGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWL 409

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1899807296 160 IIMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIMGPF 225
Cdd:COG1008   410 AILAALGLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLLGLYPQPLLDLI 475
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-167 8.36e-41

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 140.91  E-value: 8.36e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:pfam00361 123 TLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAI 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLA-NTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:pfam00361 203 FHLLTHGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIF 282


                  ....*...
gi 1899807296 160 IIMTGLGT 167
Cdd:pfam00361 283 LVLAGVVG 290
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-178 3.87e-38

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 137.76  E-value: 3.87e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFI-VLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:TIGR01972 244 VLLKMGTYGFLRFNLPLFPDASLYFAPVLaALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGA 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:TIGR01972 324 VFQMISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVV 403

                         170
                  ....*....|....*....
gi 1899807296 160 IIMTGLGTLLTATYSLHMF 178
Cdd:TIGR01972 404 AFLAALGIVLAAAYMLTLY 422
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-224 9.10e-133

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 381.47  E-value: 9.10e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00124  234 ILLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSGAM 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00124  314 ILMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPTTI 393

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1899807296 161 IMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIMGP 224
Cdd:MTH00124  394 ILTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-225 1.81e-122

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 354.99  E-value: 1.81e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00068  234 VLLKLGGYGILRISILLTPLSKELSYPFIILALWGVLMTSLICLRQTDLKSLIAYSSVSHMGLVIAAALIQTPWSFSGAI 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00068  314 ILMISHGLTSSALFCLANTNYERTHSRTLLLLRGAQTILPLMATWWLLSNLSNMALPPSPNLWGELTIMVSLFNWSNWTI 393

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1899807296 161 IMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIMGPF 225
Cdd:MTH00068  394 LITGLGTLITAAYTLYMFLMTQRGPLPNHLKTLFPTYTREHLLLALHILPMLLLILKPELISGMF 458
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-224 1.06e-116

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 340.33  E-value: 1.06e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00110  234 ILLKLGGYGMMRITIILNPLTEFMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSFMGAT 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00110  314 ALMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWLLASLTNLALPPTINLIGELFVIMSSFSWSNITI 393

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1899807296 161 IMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIMGP 224
Cdd:MTH00110  394 ILMGLNMLITALYSLYMLITTQRGKLTHHINNIKPSFTRENTLMALHLLPLLLLSLNPKIILGP 457
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-223 1.83e-96

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 289.16  E-value: 1.83e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00127  235 VLLKLGGYGMMRMMVMLDPLTKELSYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTGAL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00127  315 ILMIAHGLTSSALFCLANTNYERTHSRTMLLARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIITSLFNWSPWTL 394

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1899807296 161 IMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIMG 223
Cdd:MTH00127  395 ALTGLGTLITAGYSLYMFLMTQRGPLPDHIIALNPSHTREHLLMALHLLPLLLLILKPELIWG 457
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 1-221 5.49e-89

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 269.50  E-value: 5.49e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00206  230 VLLKLGGYGMMRIILILGPSTKLSSYFFIILGLWGSIMTSSICLRQTDLKSLIAYSSVSHMSLVTAGILSGSPWGFKGAL 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00206  310 LLMIAHGLVSSALFCLANLLYERSHTRTILGNRGLQMILPLLSFWWLLFFLANLGLPPFPNLFGELLIITSLFSWSNFTL 389

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1899807296 161 IMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALI 221
Cdd:MTH00206  390 PLLGLGFLFTAIYSLYMFVMTQHGKTPNHLLSLSPSSTREHLLLFLHLFPVILLILNPNLI 450
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 1-222 3.49e-75

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 234.48  E-value: 3.49e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTK-LYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:MTH00044  235 ILLKLGGYGLIRLINLFSLPSANnISFILIVFCCWGALITSIICLRQTDLKALIAYSSVGHMSLVAAGIFSGTNWGINGA 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:MTH00044  315 LILMIAHGLVSSALFCLANILYERSGTRTLSITRGFKLITPLLPLWWLIFCAANLGLPPLPNLIGELLIISSIISWSILS 394

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1899807296 160 IIMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIM 222
Cdd:MTH00044  395 FPIIGLATVFGAIYSLLIYQLTNSGSFPSWISNVSPISSREHLLIFLHLLPLILIIINPNIIL 457
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-222 8.09e-68

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 215.02  E-value: 8.09e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00163  222 VLLKLGGYGLLRVMSFFSKLGLKFNYIWISISLVGGVIVSLICLRQVDLKSLIAYSSVAHMGLVLGGLMTFSYWGLMGSL 301

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00163  302 LMMIGHGLCSSGLFCLANIIYERLGSRSLLINKGLLNFMPSMSLWWFLLSSSNMAAPPSLNLLGEISLINSLISWSKLSM 381

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1899807296 161 IMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIM 222
Cdd:MTH00163  382 IFLMLLSFFSAAYSLYLYSYSQHGKYYSGLYSCSSGKVREYLLLFLHWLPLNLLILKSDLFM 443
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 1-223 6.51e-63

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 201.61  E-value: 6.51e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00150  193 ILLKLGGYGILRMMMVFSLSSSSFSIFLISLSLWGGVLTSLICLRQSDVKSLIAYSSVGHMSLVLAGVLSNTSWGWVGAL 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00150  273 IMMVSHGFCSSGLFCLANYTYEKVHSRSLFLSKGMLMLYPSLSLWWFLFCIINMAAPPSLNLLSEIMIFPSLISYSPWFF 352

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1899807296 161 IMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIMG 223
Cdd:MTH00150  353 VPLGLMVFLSGLYSLYLYTSIQHGGSSSFLKPFNELKSSEMLLLLLHWVPLLLLILKSDLLFM 415
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-221 3.68e-56

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 184.94  E-value: 3.68e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00014  228 ILLKLGGYGLLRMSSLFMHINKSLSAPFSSISLVGAVITSLICIRQPDLKSLIAYSSVGHMGLMTAGIMSNTSWGWQGAL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00014  308 AMMIAHGLCSSALFALANMTYETTHTRSLFLTKGLLSLFPTMTMWWFLLSAANMAAPPSINLLSEIMLLTSILSSSLSTA 387

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1899807296 161 IMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALI 221
Cdd:MTH00014  388 ILLAITSFLAAAYSLFLYTSTQHGSPPSFMNPLNLFTPRNHTLMTLHLVPLFILILKPDLI 448
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 1-222 5.96e-56

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 184.41  E-value: 5.96e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00205  226 VLLKLGGYGLIRITSMLYKLNSNFSELFFSISLWGGVMTGMICLRQVDLKSLIAYSSVGHMGLMVVGVFSNTSWGMNGAI 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00205  306 IMMVAHGLCSSGMFALANVNYERTNSRSMLMNKGVLNTFPFLVLMWFLLISCNMAAPPSLNLASEILLIMSLLSSSKISG 385

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1899807296 161 IMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIM 222
Cdd:MTH00205  386 IPLSLISFLSGAYSLYLYSQSQHGKVSSQISSFLAISEREYYILILHWFPLNILILKLKIFI 447
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-225 4.12e-42

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 148.69  E-value: 4.12e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRIT-PMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:COG1008   250 VLLKMGGYGLLRFAlPLFPEASAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQGA 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:COG1008   330 VLQMVSHGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWL 409

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1899807296 160 IIMTGLGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLLMKPALIMGPF 225
Cdd:COG1008   410 AILAALGLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLLGLYPQPLLDLI 475
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-167 8.36e-41

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 140.91  E-value: 8.36e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:pfam00361 123 TLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQAAI 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLA-NTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:pfam00361 203 FHLLTHGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIF 282


                  ....*...
gi 1899807296 160 IIMTGLGT 167
Cdd:pfam00361 283 LVLAGVVG 290
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-178 3.87e-38

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 137.76  E-value: 3.87e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFI-VLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:TIGR01972 244 VLLKMGTYGFLRFNLPLFPDASLYFAPVLaALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGISGA 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:TIGR01972 324 VFQMISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVV 403

                         170
                  ....*....|....*....
gi 1899807296 160 IIMTGLGTLLTATYSLHMF 178
Cdd:TIGR01972 404 AFLAALGIVLAAAYMLTLY 422
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 1-179 1.25e-34

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 128.78  E-value: 1.25e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRIT-PMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:PRK05846  252 ILLKMGAYGLLRFSlPLFPDASHEFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTLGIFAGNQLGIQGA 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:PRK05846  332 IFQMISHGLSSAALFLLVGVLYDRLHTRDIADYGGLAKVMPVLAAFFLFFAMASLGLPGTSGFVGEFLILLGSFQVNPVI 411

                         170       180
                  ....*....|....*....|
gi 1899807296 160 IIMTGLGTLLTATYSLHMFL 179
Cdd:PRK05846  412 AFIATTGLILAAVYSLWLYQ 431
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 1-178 2.37e-34

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 127.87  E-value: 2.37e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIV-LAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:MTH00204  250 ILLKLGGYGFLRFSWPLFPAASEYFAPLIVmLSVIAVIYGSLTTCRQVDFKRLIAYSSVAHMGLVPLGLFTHTIEGLVAA 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:MTH00204  330 VFLMLAHGFVSSALFIAVTFLYERHHTRLIKYYRGLTLTMPLFVIIMLVLSLANMGFPLSCNFVGEFFSLLAAFEYSLGL 409

                         170
                  ....*....|....*....
gi 1899807296 160 IIMTGLGTLLTATYSLHMF 178
Cdd:MTH00204  410 GVLVTSGMVWSAAYSLYLY 428
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 1-178 2.80e-34

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 127.48  E-value: 2.80e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFI-VLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:MTH00217  247 VLLKLGGYGFIRFSWPLLPEASEYFSPLIqTLSLLAIIYGSLTTCRQVDLKRIIAYSSVAHMGLVTLGIFSHTIQGLVAA 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:MTH00217  327 IFLMLAHGLVSSALFIAVTFLYERHHTRLIKYYRGMVITMPLFGILMLLLVLANASIPLSCNFVGEFLSLLAAFEYSYIV 406

                         170
                  ....*....|....*....
gi 1899807296 160 IIMTGLGTLLTATYSLHMF 178
Cdd:MTH00217  407 GVLASLGMVLSAGYSIYLY 425
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 1-222 1.16e-31

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 120.80  E-value: 1.16e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIV-LAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:MTH00226  271 ILLKLGGYGLVRLSWPILPLGAQNLAPAVIaMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGLVSITLVTHDIIGLTGS 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:MTH00226  351 IFIMLAHGIVSSLLFILVTILYDRHHTRLIKYYRGLSITMPIWGTIMIVTSLANVAVPPSGNFIGEYLSILSSFNWNPII 430

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1899807296 160 IIMTGLGTLLTATYSLHmFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVPMALLL-MKPALIM 222
Cdd:MTH00226  431 GVFVCSGVILSAVYSFY-FANRVTFGAPGNLITFARDVNRREFYITASMVFFAFLIgIYPIFIL 493
ndhD CHL00011
NADH dehydrogenase subunit 4
 1-177 7.67e-23

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 95.78  E-value: 7.67e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFIVL-AAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:CHL00011  252 ILLKMGAYGLIRINMELLPHAHSIFSPWLVIvGAIQIIYAASTSLGQRNLKKRIAYSSVSHMGFIIIGIGSITDTGLNGA 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERThsRTMLLAR--GLQLILPLMATWWLLANLMNMALPPTINLTGELL----IITSLF 153
Cdd:CHL00011  332 ILQIISHGFIGAALFFLAGTSYDRI--RLVYLDEmgGIAIPMPKIFTMFSSFSMASLALPGMSGFVAELIvffgIITSQK 409

                         170       180
                  ....*....|....*....|....*..
gi 1899807296 154 NWSQTTIIMT---GLGTLLTATYSLHM 177
Cdd:CHL00011  410 YLLMPKILITfvmAIGMILTPIYLLSM 436
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 1-182 9.50e-23

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 95.21  E-value: 9.50e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLY--YPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTG 78
Cdd:COG0651   246 LLTKVGVYAILRVLTLLFGADPALFlgTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAG 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  79 AMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQT 158
Cdd:COG0651   326 ALFHLLNHALAKALLFLAAGAIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAW 405

                         170       180
                  ....*....|....*....|....*
gi 1899807296 159 TIIMTGL-GTLLTATYSLHMFLTTQ 182
Cdd:COG0651   406 LLAAVLLlSSLLTLAYFVRIFGRAQ 430
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-191 5.67e-22

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 93.56  E-value: 5.67e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRIT-PMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:PRK12561  226 VLLKMGGYALIRFNvQMLPDAHVYFAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLGIAAFTDLGISGA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLI---ITSLFNWS 156
Cdd:PRK12561  306 MLQMISHGLIAAALFFLTGVTYERTHTLSIPNMGGLAKVMPKTFALFTASSMASLALPGMSGFVSELTVflgITSSDVYS 385

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1899807296 157 QT----TIIMTGLGTLLTATYSLHM----FLTTQRNKLPTNII 191
Cdd:PRK12561  386 STfrtiTILLAAVGLILTPIYLLSMlrrvFYGPRSELLPALAV 428
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
1-209 9.65e-22

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 92.84  E-value: 9.65e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFI-VLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:PRK06473  246 VLLKLGTYGLLRFGVGLFPEAWVYLAPWLaTWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILLAAAAATPLSILAA 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGL---QLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWS 156
Cdd:PRK06473  326 VFQMISHGLISALLFLLVGVVYKKTGSRDVDVLRGLlnpERGLPITGSLMILGVMASAGIPGMVGFIAEFLVFRGSFPIF 405

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1899807296 157 QTTIIMTGLGTLLTATYSLHMFLTTQRNKLPTNIIN----TWPTQTREHLLMTLHIV 209
Cdd:PRK06473  406 PVQTLLCMIGTGLTAVYFLLLVNRVFFGRLTAELSNlprvLWSERLPALVLAVLIVV 462
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 1-175 2.23e-19

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 85.34  E-value: 2.23e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRItpmLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:MTH00094  192 LLLKLGTAGFLRI---LGSLNFVYNNFWIIFSLLGMILSSFCCVFQSDSKSLAAYSSVTHMSFLLLSLVYMSMSGKLSGL 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:MTH00094  269 MMMLAHGYTSTLMFYLIGEFYHISKSRLIYFMNSFFSSSMFFGLIFSLVFLSNSGVPPSLSFFSEFLIISNSFMKNKFSF 348

                         170
                  ....*....|....*
gi 1899807296 161 IMTGLGTLLTATYSL 175
Cdd:MTH00094  349 FFIFFYFLVSFYYSL 363
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-177 2.55e-18

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 82.83  E-value: 2.55e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYP-FIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:PRK02546  254 ILLKMGGYALLRMNAGMLPDAHAQFAPlLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFTDLGTSGA 333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSL------- 152
Cdd:PRK02546  334 MLQMISHGLIGASLFFLVGATYDRTHTLMLDEMGGVGQKMRKMFAMWTACSLASLALPGMSGFVAELMVFVGFatsdayt 413

                         170       180
                  ....*....|....*....|....*
gi 1899807296 153 FNWSQTTIIMTGLGTLLTATYSLHM 177
Cdd:PRK02546  414 LPFRVVVVFLAAVGVILTPIYLLSM 438
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 4-173 6.68e-14

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 69.91  E-value: 6.68e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   4 KLGGYGIIRIT----PMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:PRK08375  246 KVAVYALIRIYftvfGGDFRFALGLGWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAG 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLF---NWS 156
Cdd:PRK08375  326 LLHLLHHALMKGALFLAAGAIEVTYGTRRLSELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVeagQWL 405

                         170
                  ....*....|....*..
gi 1899807296 157 QTTIIMtgLGTLLTATY 173
Cdd:PRK08375  406 VLAVLL--ASSLLALLY 420
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
1-173 6.71e-14

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 70.13  E-value: 6.71e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPfiVLAAWG---IIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLT 77
Cdd:PRK07363  246 VLAKLGTYGLLRFGLQLFPQTWSLVAP--GLAIIGtisVIYGALSAIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLL 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  78 GAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLI---LPLMATWWLLANLMNMALPPTINLTGELLIITSLFN 154
Cdd:PRK07363  324 GAVAQMISHGLILALLFHLVGIVERKVGTRDLDVLNGLMNPirgLPLTSALLVLAGMASAGIPGLVGFVAEFIVFQGSFS 403

                         170
                  ....*....|....*....
gi 1899807296 155 WSQTTIIMTGLGTLLTATY 173
Cdd:PRK07363  404 TFPIPTLLCIVASGLTAVY 422
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 44-223 5.89e-13

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 67.26  E-value: 5.89e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  44 LRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMA 123
Cdd:PRK06458  300 LRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNHSLTKSAIFFASGNVLQKYGTRDINVIRGLLKVSPLTG 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296 124 TWWLLANLMNMALPPTINLTGELLIITSLFN---WSQTTIIMTGLGTLLTAtyslhMFLTTQRnklptNIINTWPTQTRE 200
Cdd:PRK06458  380 WGLMLGALAIAGMPPFGVFISEFLILTAGLArgpLLIAILLLLLLTLAFAA-----LVRRVAG-----MVFGEPPEAVNR 449

                         170       180
                  ....*....|....*....|...
gi 1899807296 201 HLLMTLHIVPMALLLMKPaLIMG 223
Cdd:PRK06458  450 GDLGWLTTSPMFVHLVLV-LVLG 471
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-215 1.67e-12

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 65.76  E-value: 1.67e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRI-------TPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTP 73
Cdd:PRK12667  264 LVVNVGAYAIIRFlytifgiSPSLIDFRAALSPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQ 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  74 WSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLF 153
Cdd:PRK12667  344 LGLAAALFHIINHAIAKSLLFLASGVFIHAAGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALL 423

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1899807296 154 NWSQ-TTIIMTGLGTLLTATYSLHMFLTTQRNKLPTNIIntwpTQTREHLLMTLHIVPMALLL 215
Cdd:PRK12667  424 ESGFyLPALVLLIASAISLVGYFRAWYSLFFGKPKSGEE----VEHKESPSMSVVILVLALAV 482
PRK12650 PRK12650
DUF4040 family protein;
37-175 2.18e-10

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 60.06  E-value: 2.18e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  37 IMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQ 116
Cdd:PRK12650  284 LMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTAAVVHTLAHALFKSSLFMLIGVVDHQAGTRDIRRLGSLW 363

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1899807296 117 LILPLMATWWLLANLMNMALPPTINLTGELLIITSLF-----NWSQTTIIMT-GLGTLLTATYSL 175
Cdd:PRK12650  364 RRMPFTFVSVTIAALSMAAVPPLFGFVSKEGMLTAFLeapggNAGVVLLLVGaALGAVFTFAYSA 428
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 4-181 2.88e-10

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 59.40  E-value: 2.88e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   4 KLGGYGIIRITPMLNPISTKLYyPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQtpwSLTGAMALM 83
Cdd:COG1009   255 KAGVYLLARLSPLFALSPVWLT-VVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG---AYVAALFHL 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  84 IAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTIIMT 163
Cdd:COG1009   331 LTHAFFKALLFLGAGSVIHATGTRDIRKMGGLRKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAALEAGGLGPLLL 410

                         170       180
                  ....*....|....*....|.
gi 1899807296 164 GLGTL---LTATYSLHMFLTT 181
Cdd:COG1009   411 AVALLgafLTAFYSFRLFFLV 431
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 4-168 3.55e-10

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 59.16  E-value: 3.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   4 KLGGYGIIRITPMLNpiSTKLYYpFIVLAAWGIIM--TSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMA 81
Cdd:PRK12647  239 KAGIYLLARLNPVLG--GTPLWQ-TILPLFGGLTMltGALLAVRQTDLKLILAYSTVSALGTLVMLLGLGSELAIKAAVL 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  82 LMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTII 161
Cdd:PRK12647  316 FLVAHSLYKGALFMVAGIIDHETGTRDITKLGGLRRAMPITAAAALLAALSMAGLPPLFGFLAKELIYEALLEAPLWSLI 395


                  ....*..
gi 1899807296 162 MTGLGTL 168
Cdd:PRK12647  396 LTVAAVL 402
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 1-94 8.11e-08

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 52.06  E-value: 8.11e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPML--NPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTG 78
Cdd:PRK08676  247 TVLNIGIYGILRLSALLrqSGAAEQFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFW 326

                          90
                  ....*....|....*.
gi 1899807296  79 AMALMIAHGLTSSLLF 94
Cdd:PRK08676  327 MLFHMLAHSLVKSGLF 342
PRK06525 PRK06525
hydrogenase 4 subunit D; Validated
 4-169 1.22e-07

hydrogenase 4 subunit D; Validated


Pssm-ID: 180606 [Multi-domain]  Cd Length: 479  Bit Score: 51.51  E-value: 1.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   4 KLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLV---IAATLIQTPWSLTGAM 80
Cdd:PRK06525  251 KVGVYIFARAIQSMGPIPHVIGYVGAVMAIVTLLYGFLMYLPQQDMKRLLAYSTITQLGYMffgLSLAILGSRLALEGSI 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTI 160
Cdd:PRK06525  331 AYIFNHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLKKLPLVGVGFCVAALAITGVPPFNGFFSKFPIFAAGFELSVEYW 410


                  ....*....
gi 1899807296 161 IMTGLGTLL 169
Cdd:PRK06525  411 ILLPAMVLL 419
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 29-179 1.76e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 50.97  E-value: 1.76e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  29 IVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRT 108
Cdd:PRK06589  284 IFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTPKALGAAILHLVSHSFAKICLFYSMGSIYSLKKEDQ 363

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1899807296 109 MLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQ--TTIIMTGLGTLLTATYSLHMFL 179
Cdd:PRK06589  364 VDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQpwLSIIVMLVVIASSILSALYLLK 436
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 1-153 1.86e-07

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 50.88  E-value: 1.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRItpMLNPISTKLYYPFIVLAAWGIIMTSSI--CLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTG 78
Cdd:PRK08667  246 VMLKVAVYGLVRF--LMDVLSPELWWGVLILLAGSISALLGViyALKEHDLKGLLAYSSIENIGIILMGIGLYVIFGVYG 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  79 --AMALM---------IAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELL 147
Cdd:PRK08667  324 ldTLALLalggalfhsLNHALFKSLLFLTAGSVVHATGTRNIEKMGGLVKLMPYTSALFLVGAVSIAALPPFNGFASELL 403


                  ....*.
gi 1899807296 148 IITSLF 153
Cdd:PRK08667  404 LYESFF 409
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 2-152 4.52e-07

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 50.00  E-value: 4.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   2 LLKLGGYGIIRITPMLnpISTKLY-------------YPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAAT 68
Cdd:PRK08668  238 LSKLGAYGFLLVLYVL--PGTKLFsefgtyrgvplfnYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGL 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  69 LIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLI 148
Cdd:PRK08668  316 GLGTSLGFAGGLFHVFNHALFKGLFFLIFAAVIYRTGTTKISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLI 395


                  ....
gi 1899807296 149 ITSL 152
Cdd:PRK08668  396 FEAL 399
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 4-173 4.52e-07

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 49.77  E-value: 4.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   4 KLGGYGIIRITPMLNPIS--TKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMA 81
Cdd:PRK08377  250 KAGLYAMARILYLMQNANgwSSVLKLVIIMATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIALALALGTQAGVDAGVF 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  82 LMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTII 161
Cdd:PRK08377  330 HMINHAIVKALLFLAVGYVGITLGGTEIEKFEGLGKRMPLTALALTIGALSTVGIPLFNVFWSKFRIILAGLSAGYTWPV 409

                         170
                  ....*....|...
gi 1899807296 162 MTGLG-TLLTATY 173
Cdd:PRK08377  410 ALVLGaSVVEAVY 422
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 4-175 4.70e-07

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 49.92  E-value: 4.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   4 KLGGYGIIRITPMLNPISTkLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALM 83
Cdd:PRK12644  247 KAGIYLVARLAPGFADVPV-WRPTVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALAGLAML 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  84 IAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLAnLMNMA-LPPTINLTGELLIITSLFN------WS 156
Cdd:PRK12644  326 LAHALFKAALFLVVGIIDHSTGTRDIRKLSGLGRRQPVLAVVAALA-AASMAgLPPLLGFVAKEAALEAVLHdgalgpAG 404

                         170
                  ....*....|....*....
gi 1899807296 157 QTTIIMTGLGTLLTATYSL 175
Cdd:PRK12644  405 PVVLAGIVLGSILTVAYSL 423
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 28-151 1.41e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 48.19  E-value: 1.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  28 FIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANT---NYERT 104
Cdd:PRK12662  282 FMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVNHSIVKSALFMVSGSisyHFGTT 361

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1899807296 105 HSRTMLlarGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITS 151
Cdd:PRK12662  362 KLEDCL---NLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDA 405
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 4-167 4.45e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 46.87  E-value: 4.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   4 KLGGYGIIRITPMLNpistKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIqtpwsltgAMALM 83
Cdd:PRK07234  228 KAGVFPLVRCALDVP----GLDLIVRIFGVGTALLGVLFALLEKDLKRMLAFSTISQLGFILAAPLV--------GGLYA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  84 IAHGLTSSLLFCLANTNYERTHS--RTMLLARGLQLILplmatwwLLANLMNMALPPTINLTGELLIITSLFNWSQTTII 161
Cdd:PRK07234  296 LAHGLVKSTLFLCAGALPSRNFTelISQMLGIGKWIPL-------TMASFSIAGFPLLAGFVSKVLTLKNLLPWQAIALN 368


                  ....*.
gi 1899807296 162 MTGLGT 167
Cdd:PRK07234  369 LAAVGT 374
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 44-154 8.78e-06

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 45.88  E-value: 8.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  44 LRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLF-CLANTNYERTHSRTMLLARGLQLILPLM 122
Cdd:COG1007   288 LAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAYLFMNLGAFaVILLLSRKGGEAEEIEDLAGLARRSPLL 367

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1899807296 123 AtwWLLANLM-NMA-LPPTINLTGELLIITSLFN 154
Cdd:COG1007   368 A--LAMTIFLlSLAgIPPTAGFFGKFYVFSAAVE 399
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
4-90 2.46e-05

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 44.43  E-value: 2.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   4 KLGGYGII-RITPM-LNPISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMA 81
Cdd:PRK05777  247 KIAAFAVLlRLLVVaFGGLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLF 326


                  ....*....
gi 1899807296  82 LMIAHGLTS 90
Cdd:PRK05777  327 YLLAYLFMT 335
PRK06521 PRK06521
hydrogenase 4 subunit B; Validated
 1-153 6.94e-05

hydrogenase 4 subunit B; Validated


Pssm-ID: 235820 [Multi-domain]  Cd Length: 667  Bit Score: 43.34  E-value: 6.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTkLYYPFIVLAAWGIIMTSSI--CLRQTDLKSLIAYSSVSHMGLVI------------- 65
Cdd:PRK06521  251 VMLKVAIYGILRVVFDLLGAPG-WWWGVLVLALGAISAVLGVlyALAEHDLKRLLAYSTIENIGIIFvglglamvfiayg 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  66 ---AATLiqtpwSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINL 142
Cdd:PRK06521  330 mplLAAL-----ALTAALYHLLNHALFKSLLFLGAGAVLHATGTRDMEKLGGLIRRMPWTAWAFLIGCLAISALPPLNGF 404

                         170
                  ....*....|.
gi 1899807296 143 TGELLIITSLF 153
Cdd:PRK06521  405 VSEWLLLQSLL 415
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
29-138 9.05e-05

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 42.71  E-value: 9.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  29 IVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRT 108
Cdd:PRK06277  270 IALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVAGIFHAINHVIYKSALFLGAGIVSYRTKTSN 349

                          90       100       110
                  ....*....|....*....|....*....|
gi 1899807296 109 MLLARGLQLILPLMATWWLLANLMNMALPP 138
Cdd:PRK06277  350 LRKLGGLLPVMPVVAFMVLCAKLAISGVPP 379
PRK12646 PRK12646
DUF4040 family protein;
2-177 2.50e-04

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 41.66  E-value: 2.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   2 LLKLGGYGIIRITPMLNpISTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLV-----IAATLIQTP--- 73
Cdd:PRK12646  252 MVKAGIFLLFRFTPLLG-LSNMYIYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMImamvgIGGGYAQHQqda 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  74 ------WSLTGAMALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLAnLMNMALPPTIN--LTGE 145
Cdd:PRK12646  331 iasiyvFVLFAALFHLMNHAIFKCALFMGVGIIDHEAGTRDIRILSGMRQLFPKMNLVMTIA-ALSMAGVPFLNgfLSKE 409

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1899807296 146 LLI--ITSLFNWSQ----TTIIMTGLG---TLLTATYSLHM 177
Cdd:PRK12646  410 MFLdaLTQTGQLSQfsliSMIIIVFIGviaSIFTFTYALYM 450
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-180 3.23e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 41.09  E-value: 3.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPISTKLYYPFI-VLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGA 79
Cdd:PRK07691  250 LLTKVGVYAIARTFTLFFSHDTSFTHYLIlILALLTIIFGVIGAVAYFDIKKIIIYNIMIAVGVILVGVAMMTESGMIGA 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  80 MALMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTT 159
Cdd:PRK07691  330 IYYLIHDMIVKAALFLLIGIMIKITGTTDLKKMGGLIKRYPVLGWMFFIAALSLAGIPPLSGFYGKFFIVEGTFEAGFYV 409

                         170       180
                  ....*....|....*....|..
gi 1899807296 160 IIMTGLGTLLTATYS-LHMFLT 180
Cdd:PRK07691  410 SGIIVLLSSLLVLYSvIKIFLK 431
ND5 MTH00207
NADH dehydrogenase subunit 5; Provisional
 2-181 4.74e-04

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 164753 [Multi-domain]  Cd Length: 572  Bit Score: 40.90  E-value: 4.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   2 LLKLGGYGIIRITPMLNpiSTKLYYPFIVL-AAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPwslTGAM 80
Cdd:MTH00207  221 LVTAGVFLLIRFYPFLS--STYWFNPALLLtASLTMLMAGLSAMTECDMKKIIALSTLSQLGVMMASLGLGMP---KLAL 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTSSLLFCLANTN-YERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITS--LFNWSQ 157
Cdd:MTH00207  296 FHLITHALFKALLFVCAGSLiHSHHHSQDLRTMGNLTNQMPLTTSCLLIANLALCGSPFLSGFYSKDLILESslFYPHNS 375

                         170       180
                  ....*....|....*....|....
gi 1899807296 158 TTIIMTGLGTLLTATYSLHMFLTT 181
Cdd:MTH00207  376 LMILMIFLATALTAAYSTRFTLAV 399
ND4 MTH00062
NADH dehydrogenase subunit 4; Provisional
 3-154 8.20e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214413 [Multi-domain]  Cd Length: 417  Bit Score: 39.91  E-value: 8.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   3 LKLGGYGIIRITPMLNPISTKLYYPFIVLAAWGIIMTSSICLrqtDLKSLIAYSSVSHMgLVIAATLIQTPWSLTG-AMA 81
Cdd:MTH00062  208 MKLGLLGVYRFCGFIFSGSFLGYLFLCCLFSVFFLITACSEL---DGKRWLAFLSLSHI-LVPVLGLFVGDWSSINlSFF 283

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1899807296  82 LMIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLIITSLFN 154
Cdd:MTH00062  284 YCLGHGLSAGLVFLLLWCFYEVSGSRNWVLLKSGINGSLVLRVIVVFSFLSLCSFPPTIQFFCEVFLVSSSFG 356
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 1-222 9.28e-04

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 39.93  E-value: 9.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   1 ILLKLGGYGIIRITPMLNPIstklyypFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIQTPWSLTGAM 80
Cdd:TIGR01770 252 VFLRLFLYILFGFSEAWQIF-------LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVL 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  81 ALMIAHGLTS----SLLFCLANTNYERTHSrtMLLARGLQLILPLMATWWLLaNLMNMA-LPPTINLTGELLIITSLFNW 155
Cdd:TIGR01770 325 FYIFIYALMSlgafGVLSLLRSYKDEWIEY--ISDFAGLFKTNPILAILILI-FMFSLAgIPPLAGFFGKFYVFFALLKS 401

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1899807296 156 SQTTIIMTG-LGTLLTATYSLHMFLTTQRNKLPTNIINTWPTQTREHLLMTLHIVpMALLLMKPALIM 222
Cdd:TIGR01770 402 GLYWLAVIAvLTSVIGAFYYLRVVKVMYFDKPERRIPSNPQSKAQSLLLSISALF-ILFLGLFPSLIL 468
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 15-179 1.86e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 38.71  E-value: 1.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  15 PMLNPiSTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLIqTPWSLTgaMALMIAHGLTSSLLF 94
Cdd:MTH00144  135 SNFLD-LYWLAYLLCVISVLSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILH-GSWLMW--MYFLIYIVSSGFLFF 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  95 CLANTNYERTHSRTMLLARglqlilPLMATWWLLANLMNMALPPTINLTGELLIITSLFNWSQTTIIMTG-LGTLLTATY 173
Cdd:MTH00144  211 SLWSGDSGSMKDLGSLKPS------YKTGLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLlLGSLISLFF 284


                  ....*.
gi 1899807296 174 SLHMFL 179
Cdd:MTH00144  285 YLSVFF 290
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 6-170 2.16e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 38.54  E-value: 2.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296   6 GGYGIIRI-----TPMLNPisTKLYYPFIVLAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLVI------AATLIQTPW 74
Cdd:PRK08376  265 GLYALARVlfsiyGPAINL--ATVGWVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLlglgvgLAALGDPAM 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  75 SLTGAMAL------MIAHGLTSSLLFCLANTNYERTHSRTMLLARGLQLILPLMATWWLLANLMNMALPPTINLTGELLI 148
Cdd:PRK08376  343 ASYGEIALaggiyhIVNHALYKALLFLTAGAVIYETGTRNLNELGGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422

                         170       180
                  ....*....|....*....|..
gi 1899807296 149 ITSLFNWSQTTIIMTGLGTLLT 170
Cdd:PRK08376  423 YESSALFNPILGVIAMIGSVLT 444
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 17-163 4.15e-03

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 37.45  E-value: 4.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899807296  17 LNPISTKLYYPFIvlAAWGIIMTSSICLRQTDLKSLIAYSSVSHMGLViaaTLIQTPWSLTGAMALMIAHGLTSSLLFCL 96
Cdd:MTH00011  141 FTSHNILPMMTSM--AAMSALAGGLGGMNQTQLRPLLAYSSIGHMGWM---TMISVFSPSMAILYFMTYIIITTPLMLLF 215

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1899807296  97 ANTNYERTHSRTMLLArglqliLPLMATWWLLANLMNMA-LPPTINLTGELLIITSLFNWSQTTIIMT 163
Cdd:MTH00011  216 AYLNAFSTKFNSKISS------MSQTTSMSLFIMLLSLGgLPPFTGFMPKLMAIETLTSNSMILILLV 277
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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