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Conserved domains on  [gi|1899467643|gb|QNP45303|]
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aspartyl/asparaginyl beta-hydroxylase domain-containing protein [Sphingomonas sediminicola]

Protein Classification

aspartyl/asparaginyl beta-hydroxylase domain-containing protein( domain architecture ID 10523946)

aspartyl/asparaginyl beta-hydroxylase domain-containing protein is an iron (II)/2-oxoglutarate-dependent oxygenase which catalyzes an oxidative reaction in one of a wide range of metabolic processes; belongs to the cupin superfamily

CATH:  2.60.120.10
Gene Ontology:  GO:0046872
PubMed:  14697267|19478949
SCOP:  3001825

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LpxO2 COG3555
Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, ...
 210-419 1.54e-81

Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 442776  Cd Length: 220  Bit Score: 249.79  E-value: 1.54e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643 210 LHYPFLPADEFFDRGHFPWLEQLEAATPEIIKELQAILAERDsGVAPYISMPPGVppnkwSRLDKSLDWGAFHLWKEGVR 289
Cdd:COG3555     1 YRFSGLPTTPFFDRAQFPWLAELEANWPTIRAELLALLAEIE-ALPPYHDISFDQ-----ANIFFDRGWKRFYLYWYGER 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643 290 MDDACARAPRTTELVESLPLCriegraPAVFFSILKAGSHIPPHTGVTNVRSIVHLPLIVP--EGCGFRVGGETREWRVG 367
Cdd:COG3555    75 HPSNCALCPKTAALLEQIPGV------KAAMFSILPPGKHIPPHRGPYNGRLRYHLGLIVPndDRCRIRVDGETYSWREG 148

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1899467643 368 EAFVFDDTIEHEAWNRSGHDRAILIIDTWNPHLSEHER------EMIVRFYAAADEQR 419
Cdd:COG3555   149 EAVLFDDTYEHEAWNDTDETRVVLFCDVWRPMLSPWERavnrlfAAILMRSAFVPNAR 206
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 3-138 6.24e-18

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 79.85  E-value: 6.24e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   3 SGSIQQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLAR 82
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1899467643  83 AHRELGDSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVALS 138
Cdd:COG4783    81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
 
Name Accession Description Interval E-value
LpxO2 COG3555
Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, ...
 210-419 1.54e-81

Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442776  Cd Length: 220  Bit Score: 249.79  E-value: 1.54e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643 210 LHYPFLPADEFFDRGHFPWLEQLEAATPEIIKELQAILAERDsGVAPYISMPPGVppnkwSRLDKSLDWGAFHLWKEGVR 289
Cdd:COG3555     1 YRFSGLPTTPFFDRAQFPWLAELEANWPTIRAELLALLAEIE-ALPPYHDISFDQ-----ANIFFDRGWKRFYLYWYGER 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643 290 MDDACARAPRTTELVESLPLCriegraPAVFFSILKAGSHIPPHTGVTNVRSIVHLPLIVP--EGCGFRVGGETREWRVG 367
Cdd:COG3555    75 HPSNCALCPKTAALLEQIPGV------KAAMFSILPPGKHIPPHRGPYNGRLRYHLGLIVPndDRCRIRVDGETYSWREG 148

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1899467643 368 EAFVFDDTIEHEAWNRSGHDRAILIIDTWNPHLSEHER------EMIVRFYAAADEQR 419
Cdd:COG3555   149 EAVLFDDTYEHEAWNDTDETRVVLFCDVWRPMLSPWERavnrlfAAILMRSAFVPNAR 206
Asp_Arg_Hydrox pfam05118
Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases ...
 233-398 2.06e-51

Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyze oxidative reactions in a range of metabolic processes. Proline 3-hydroxylase hydroxylates proline at position 3, the first of a 2-OG oxygenase catalysing oxidation of a free alpha-amino acid. The structure of proline 3-hydroxylase contains the conserved motifs present in other 2-OG oxygenases including a jelly roll strand core and residues binding iron and 2-oxoglutarate, consistent with divergent evolution within the extended family. This family represent the arginine, asparagine and proline hydroxylases. The aspartyl/asparaginyl beta-hydroxylase (EC:1.14.11.16) specifically hydroxylates one aspartic or asparagine residue in certain epidermal growth factor-like domains of a number of proteins.


Pssm-ID: 461552  Cd Length: 157  Bit Score: 170.14  E-value: 2.06e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643 233 EAATPEIIKELQAILAERDSGVAPyismppgvpPNKWSRLDKSLDWGAFHLWKEGVRMDDACARAPRTTELVESLPLCRI 312
Cdd:pfam05118   1 EANWQVIRDELLALLKQEEGLPPY---------EEEALDDFGDIGWKTFYLYAYGARLPENCALCPKTAALLEQPGVKAS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643 313 EGRAPAVFFSILKAGSHIPPHTGVTNVRSIVHLPLIVPEGCGFRVGGETREWRVGEAFVFDDTIEHEAWNRSGHDRAILI 392
Cdd:pfam05118  72 GCPRGQAMFSRLQPGTHIPPHRGPTNGRLRCHLGLVVPPGCRIRVGGETRTWREGECLLFDDSFEHEAWNETDEPRVVLL 151


                  ....*.
gi 1899467643 393 IDTWNP 398
Cdd:pfam05118 152 VDVWRP 157
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 3-138 6.24e-18

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 79.85  E-value: 6.24e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   3 SGSIQQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLAR 82
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1899467643  83 AHRELGDSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVALS 138
Cdd:COG4783    81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 1-131 3.51e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.94  E-value: 3.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   1 MTSGSIQQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNL 80
Cdd:TIGR02917 426 LDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANL 505

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1899467643  81 ARAHRELGDSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEAlGAKRW 131
Cdd:TIGR02917 506 ARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEE-EAVAW 555
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 7-81 1.27e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.85  E-value: 1.27e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1899467643   7 QQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQP-LWMNLA 81
Cdd:cd24142     1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYeKYLYLG 76
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 13-125 2.00e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 46.34  E-value: 2.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  13 AQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMN-LARAHRELGDSE 91
Cdd:PRK11788  187 AQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQDPEYLSEVLPkLMECYQALGDEA 266

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1899467643  92 AERAALEKVLTiDQRDLLALIRLAELHERLGEEA 125
Cdd:PRK11788  267 EGLEFLRRALE-EYPGADLLLALAQLLEEQEGPE 299
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 10-73 2.56e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.24  E-value: 2.56e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1899467643  10 LAEAQRAMHAGQVDKARHHLDAVIELDPTEP---NARNALGLFALDQGDARAAAAHFEIACDRDPKA 73
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPdaaAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
 
Name Accession Description Interval E-value
LpxO2 COG3555
Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, ...
 210-419 1.54e-81

Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442776  Cd Length: 220  Bit Score: 249.79  E-value: 1.54e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643 210 LHYPFLPADEFFDRGHFPWLEQLEAATPEIIKELQAILAERDsGVAPYISMPPGVppnkwSRLDKSLDWGAFHLWKEGVR 289
Cdd:COG3555     1 YRFSGLPTTPFFDRAQFPWLAELEANWPTIRAELLALLAEIE-ALPPYHDISFDQ-----ANIFFDRGWKRFYLYWYGER 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643 290 MDDACARAPRTTELVESLPLCriegraPAVFFSILKAGSHIPPHTGVTNVRSIVHLPLIVP--EGCGFRVGGETREWRVG 367
Cdd:COG3555    75 HPSNCALCPKTAALLEQIPGV------KAAMFSILPPGKHIPPHRGPYNGRLRYHLGLIVPndDRCRIRVDGETYSWREG 148

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1899467643 368 EAFVFDDTIEHEAWNRSGHDRAILIIDTWNPHLSEHER------EMIVRFYAAADEQR 419
Cdd:COG3555   149 EAVLFDDTYEHEAWNDTDETRVVLFCDVWRPMLSPWERavnrlfAAILMRSAFVPNAR 206
Asp_Arg_Hydrox pfam05118
Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases ...
 233-398 2.06e-51

Aspartyl/Asparaginyl beta-hydroxylase; Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyze oxidative reactions in a range of metabolic processes. Proline 3-hydroxylase hydroxylates proline at position 3, the first of a 2-OG oxygenase catalysing oxidation of a free alpha-amino acid. The structure of proline 3-hydroxylase contains the conserved motifs present in other 2-OG oxygenases including a jelly roll strand core and residues binding iron and 2-oxoglutarate, consistent with divergent evolution within the extended family. This family represent the arginine, asparagine and proline hydroxylases. The aspartyl/asparaginyl beta-hydroxylase (EC:1.14.11.16) specifically hydroxylates one aspartic or asparagine residue in certain epidermal growth factor-like domains of a number of proteins.


Pssm-ID: 461552  Cd Length: 157  Bit Score: 170.14  E-value: 2.06e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643 233 EAATPEIIKELQAILAERDSGVAPyismppgvpPNKWSRLDKSLDWGAFHLWKEGVRMDDACARAPRTTELVESLPLCRI 312
Cdd:pfam05118   1 EANWQVIRDELLALLKQEEGLPPY---------EEEALDDFGDIGWKTFYLYAYGARLPENCALCPKTAALLEQPGVKAS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643 313 EGRAPAVFFSILKAGSHIPPHTGVTNVRSIVHLPLIVPEGCGFRVGGETREWRVGEAFVFDDTIEHEAWNRSGHDRAILI 392
Cdd:pfam05118  72 GCPRGQAMFSRLQPGTHIPPHRGPTNGRLRCHLGLVVPPGCRIRVGGETRTWREGECLLFDDSFEHEAWNETDEPRVVLL 151


                  ....*.
gi 1899467643 393 IDTWNP 398
Cdd:pfam05118 152 VDVWRP 157
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 3-138 6.24e-18

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 79.85  E-value: 6.24e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   3 SGSIQQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLAR 82
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1899467643  83 AHRELGDSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVALS 138
Cdd:COG4783    81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
9-205 9.82e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.20  E-value: 9.82e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   9 HLAEAQRAMhaGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELG 88
Cdd:COG0457    13 NLGLAYRRL--GRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  89 DSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVALSSGIPDR-------LPELEQIVDHAKAFVQK 161
Cdd:COG0457    91 RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADAlynlgiaLEKLGRYEEALELLEKL 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1899467643 162 HRQHLANAIDAKLADDLSGASTRDRRRLQAAADHWLGRRGIYAN 205
Cdd:COG0457   171 EAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAIL 214
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 6-194 1.10e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 76.69  E-value: 1.10e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   6 IQQHLAEAQraMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHR 85
Cdd:COG2956    78 ALLELAQDY--LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  86 ELGDSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVALSSGIPDRLPELEQI------VDHAKAFV 159
Cdd:COG2956   156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELyeklgdPEEALELL 235

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1899467643 160 QKH-RQHLANAIDAKLADDLsgastRDRRRLQAAAD 194
Cdd:COG2956   236 RKAlELDPSDDLLLALADLL-----ERKEGLEAALA 266
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
9-194 4.08e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.58  E-value: 4.08e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   9 HLAEAQRAMhaGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELG 88
Cdd:COG0457    47 NLGLAYLRL--GRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  89 DSEAERAALEKVLTIDQRDLLALIRLAELHERLG--EEALGAKRWGAVVALSSGIPDRLPELEQIVDHAKAFVQKHRQHL 166
Cdd:COG0457   125 RYDEAIEAYERALELDPDDADALYNLGIALEKLGryEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALE 204

                         170       180
                  ....*....|....*....|....*...
gi 1899467643 167 ANAIDAKLADDLSGASTRDRRRLQAAAD 194
Cdd:COG0457   205 QALRKKLAILTLAALAELLLLALALLLA 232
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 10-123 1.17e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 1.17e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  10 LAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGD 89
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1899467643  90 SEAERAALEKVLTIDQRDLLALIRLAELHERLGE 123
Cdd:COG2956    92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGD 125
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 9-107 3.28e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.67  E-value: 3.28e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   9 HLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELG 88
Cdd:COG4783    41 FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALG 120

                          90
                  ....*....|....*....
gi 1899467643  89 DSEAERAALEKVLTIDQRD 107
Cdd:COG4783   121 RPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 24-151 6.00e-12

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 62.72  E-value: 6.00e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  24 KARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDSEAERAALEKVLTI 103
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1899467643 104 DQRDLLALIRLAELHERLGEEALGAKRWGAVVALSSGIPDRLPELEQI 151
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 9-137 6.17e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.52  E-value: 6.17e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   9 HLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELG 88
Cdd:COG2956    45 HLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEG 124

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1899467643  89 DSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVAL 137
Cdd:COG2956   125 DWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKL 173
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
16-104 9.36e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 60.95  E-value: 9.36e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  16 AMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAhFEIACDRDPKAQPLWMNLARAHRELGDSEAERA 95
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80


                  ....*....
gi 1899467643  96 ALEKVLTID 104
Cdd:COG3063    81 YLERALELD 89
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 9-114 3.04e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.40  E-value: 3.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   9 HLAEAQRAMhaGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELG 88
Cdd:COG3914   117 NLGNLLLAL--GRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLG 194

                          90       100
                  ....*....|....*....|....*.
gi 1899467643  89 DSEAERAALEKVLTIDQRDLLALIRL 114
Cdd:COG3914   195 RLEEAIAAYRRALELDPDNADAHSNL 220
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
7-125 3.60e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 62.63  E-value: 3.60e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   7 QQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRE 86
Cdd:COG4785    74 QLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYY 153

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1899467643  87 LGDSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEA 125
Cdd:COG4785   154 LGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEK 192
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
33-126 4.23e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.72  E-value: 4.23e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  33 IELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDSEAERAALEKVLTIDQRDLLALI 112
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90
                  ....*....|....*.
gi 1899467643 113 RLAELHERLG--EEAL 126
Cdd:COG0457    81 NLGLALQALGryEEAL 96
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 16-104 1.18e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 59.59  E-value: 1.18e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  16 AMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDSEAERA 95
Cdd:COG5010    64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143


                  ....*....
gi 1899467643  96 ALEKVLTID 104
Cdd:COG5010   144 ALQRALGTS 152
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 4-137 1.22e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.47  E-value: 1.22e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   4 GSIQQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARA 83
Cdd:COG3914    42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNL 121

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1899467643  84 HRELGDSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVAL 137
Cdd:COG3914   122 LLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALEL 175
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 4-107 1.21e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.17  E-value: 1.21e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   4 GSIQQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARA 83
Cdd:COG4235    15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLA 94

                          90       100
                  ....*....|....*....|....
gi 1899467643  84 HRELGDSEAERAALEKVLTIDQRD 107
Cdd:COG4235    95 AFQQGDYAEAIAAWQKLLALLPAD 118
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 1-131 3.51e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.94  E-value: 3.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   1 MTSGSIQQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNL 80
Cdd:TIGR02917 426 LDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANL 505

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1899467643  81 ARAHRELGDSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEAlGAKRW 131
Cdd:TIGR02917 506 ARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEE-EAVAW 555
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 14-101 1.23e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 49.99  E-value: 1.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  14 QRAMHAGQVDKARHHLDAVIELDPTEPNARNA---LGLFALDQGDARAAAAHFEIACDRDP---KAQPLWMNLARAHREL 87
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRYPNSPLAPDAlywLGEAYYALGDYDEAAEAFEKLLKRYPdspKAPDALLKLGLSYLEL 80

                          90
                  ....*....|....
gi 1899467643  88 GDSEAERAALEKVL 101
Cdd:COG1729    81 GDYDKARATLEELI 94
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 16-136 2.86e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.78  E-value: 2.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  16 AMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDP------------------------ 71
Cdd:TIGR02917 373 YLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPelgradlllilsylrsgqfdkala 452

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1899467643  72 ------KAQP----LWMNLARAHRELGDSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVA 136
Cdd:TIGR02917 453 aakkleKKQPdnasLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLT 527
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 8-138 3.49e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.57  E-value: 3.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   8 QHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHREL 87
Cdd:COG5010    22 TLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRS 101

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1899467643  88 GDSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVALS 138
Cdd:COG5010   102 GDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 42-151 4.76e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.65  E-value: 4.76e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  42 ARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDSEAERAALEKVLTIDQRDLLALIRLAELHERL 121
Cdd:COG4783     6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                          90       100       110
                  ....*....|....*....|....*....|
gi 1899467643 122 GEEALGAKRWGAVVALSSGIPDRLPELEQI 151
Cdd:COG4783    86 GDYDEALALLEKALKLDPEHPEAYLRLARA 115
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 9-104 2.15e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.96  E-value: 2.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   9 HLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAqPLWMNLARAHRELG 88
Cdd:COG2956   181 LLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKE 259

                          90
                  ....*....|....*.
gi 1899467643  89 DSEAERAALEKVLTID 104
Cdd:COG2956   260 GLEAALALLERQLRRH 275
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 13-78 4.13e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.77  E-value: 4.13e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1899467643  13 AQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWM 78
Cdd:COG4235    58 AEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARL 123
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 10-148 4.41e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 4.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  10 LAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLwMNLARAHRELGD 89
Cdd:TIGR02917 673 IGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNA-IKLHRALLASGN 751

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1899467643  90 SEAERAALEKVLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVALSsgiPDRLPEL 148
Cdd:TIGR02917 752 TAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKA---PDNAVVL 807
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 4-120 7.55e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 7.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   4 GSIQQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARA 83
Cdd:TIGR02917 531 KNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRA 610

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1899467643  84 HRELGDSEAERAALEKVLTIDQRDLLALIRLAELHER 120
Cdd:TIGR02917 611 QLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAV 647
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 20-131 1.13e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.77  E-value: 1.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  20 GQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDSEAERAALEK 99
Cdd:TIGR02917 343 GRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLET 422

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1899467643 100 VLTIDQRDLLALIRLAELHERLGEEALG---AKRW 131
Cdd:TIGR02917 423 AAQLDPELGRADLLLILSYLRSGQFDKAlaaAKKL 457
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 7-81 1.27e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.85  E-value: 1.27e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1899467643   7 QQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQP-LWMNLA 81
Cdd:cd24142     1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYeKYLYLG 76
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 13-125 2.00e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 46.34  E-value: 2.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  13 AQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMN-LARAHRELGDSE 91
Cdd:PRK11788  187 AQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQDPEYLSEVLPkLMECYQALGDEA 266

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1899467643  92 AERAALEKVLTiDQRDLLALIRLAELHERLGEEA 125
Cdd:PRK11788  267 EGLEFLRRALE-EYPGADLLLALAQLLEEQEGPE 299
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 4-116 2.61e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 2.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   4 GSIQQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARA 83
Cdd:TIGR02917 225 NNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGAS 304

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1899467643  84 HRELGDSEAERAALEKVLTIDQ-----RDLLALIRLAE 116
Cdd:TIGR02917 305 EYQLGNLEQAYQYLNQILKYAPnshqaRRLLASIQLRL 342
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 9-180 4.75e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 44.90  E-value: 4.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   9 HLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQ-PLWMNLARAHREL 87
Cdd:COG3071    19 ALLEGLLALAEGRYARAEKLLSKAAEHSEAPLLAYLLAARAAQALGDYERRDEYLAQALELAPEAElAVLLTRAELLLDQ 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  88 GDSEAERAALEKVLTIDQRDLLALIRLAELHERLGeealgakRWGAVVALssgipdrLPELEQIVDHAKAFVQKHRQHLA 167
Cdd:COG3071    99 GQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLG-------DWEELLEL-------LPALRKHKALSAEEAQALERRAY 164

                         170
                  ....*....|...
gi 1899467643 168 NAIDAKLADDLSG 180
Cdd:COG3071   165 LGLLRQAARDAEA 177
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 10-101 7.56e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 7.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  10 LAEAQRAmhAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGD 89
Cdd:TIGR02917 742 LHRALLA--SGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKD 819

                          90
                  ....*....|..
gi 1899467643  90 SEAERAAlEKVL 101
Cdd:TIGR02917 820 PRALEYA-ERAL 830
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 13-129 1.03e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  13 AQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDsea 92
Cdd:TIGR02917 506 ARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQ--- 582

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1899467643  93 eraaLEKVLTIdQRDLLALIRLA-ELHERLGEEALGAK 129
Cdd:TIGR02917 583 ----LKKALAI-LNEAADAAPDSpEAWLMLGRAQLAAG 615
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 20-127 1.31e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 1.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  20 GQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDSEAERAALEK 99
Cdd:TIGR02917 479 GDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEK 558

                          90       100
                  ....*....|....*....|....*...
gi 1899467643 100 VLTIDQRDLLALIRLAELHERLGEEALG 127
Cdd:TIGR02917 559 AAELNPQEIEPALALAQYYLGKGQLKKA 586
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
19-92 1.73e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.59  E-value: 1.73e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1899467643  19 AGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDSEA 92
Cdd:COG4785   120 LGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDPEKA 193
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 10-73 2.56e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.24  E-value: 2.56e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1899467643  10 LAEAQRAMHAGQVDKARHHLDAVIELDPTEP---NARNALGLFALDQGDARAAAAHFEIACDRDPKA 73
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPdaaAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
29-157 2.84e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.21  E-value: 2.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  29 LDAVIELDPTEPNARNALGLFA-----LDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDSEAERAALEKVLTI 103
Cdd:COG4785    57 ALAAERIDRALALPDLAQLYYErgvayDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALEL 136

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1899467643 104 DQRDLLALIRLAELHERLGEEALGAKRWGAVVALSSGIPDRLPEL---EQIVDHAKA 157
Cdd:COG4785   137 DPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLylaERKLDPEKA 193
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 20-181 5.43e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.38  E-value: 5.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  20 GQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDSEAERAALEK 99
Cdd:TIGR02917 139 GQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRK 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643 100 VLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVALSSGIPDrlpeleqiVDHAKAFVQKHRQHLANAIDAkLADDLS 179
Cdd:TIGR02917 219 AIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPL--------AHYLKALVDFQKKNYEDARET-LQDALK 289


                  ..
gi 1899467643 180 GA 181
Cdd:TIGR02917 290 SA 291
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 17-73 1.06e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.56  E-value: 1.06e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1899467643  17 MHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKA 73
Cdd:COG5010    99 SRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPLK 155
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 18-127 1.82e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  18 HAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDSEAERAAL 97
Cdd:TIGR02917 307 QLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYL 386

                          90       100       110
                  ....*....|....*....|....*....|
gi 1899467643  98 EKVLTIDQRDLLALIRLAELHERLGEEALG 127
Cdd:TIGR02917 387 AKATELDPENAAARTQLGISKLSQGDPSEA 416
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
55-249 2.09e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 2.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   55 DARAAAAHFEiacdrdpkaqplwmNLARAHRELGDSEAERAALEKVLTIDQRdllaLIRLAELHERLGEEALGAKRWGAV 134
Cdd:COG4913    226 AADALVEHFD--------------DLERAHEALEDAREQIELLEPIRELAER----YAAARERLAELEYLRAALRLWFAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  135 VALSSgIPDRLPELEQIVDHAKAFVQKHRQHLANAID--AKLADDLSGAS-------TRDRRRLQAAADHWLGRRGIYAN 205
Cdd:COG4913    288 RRLEL-LEAELEELRAELARLEAELERLEARLDALREelDELEAQIRGNGgdrleqlEREIERLERELEERERRRARLEA 366

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1899467643  206 HCEGLHYPFLPADEFFDRGHFPWLEQLEAAtPEIIKELQAILAE 249
Cdd:COG4913    367 LLAALGLPLPASAEEFAALRAEAAALLEAL-EEELEALEEALAE 409
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
3-125 2.23e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.48  E-value: 2.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   3 SGSIQQHLAEAQRAMHAGQVDKARHHLDAVIE-LDPTEPNARNALGLFALDQGDARAAAAHFE--IACDRDPKAQPLWMN 79
Cdd:COG4700    86 ADTVQNRVRLADALLELGRYDEAIELYEEALTgIFADDPHILLGLAQALFELGRYAEALETLEklIAKNPDFKSSDAHLL 165

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1899467643  80 LARAHRELGDSEAERAALEKvltIDQR--DLLALIRLAELHERLGEEA 125
Cdd:COG4700   166 YARALEALGDLEAAEAELEA---LARRysGPEARYRYAKFLARQGRTA 210
TPR_19 pfam14559
Tetratricopeptide repeat;
53-117 2.78e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.02  E-value: 2.78e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1899467643  53 QGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGDSEAERAALEKVLTIDQRDLLALIRLAEL 117
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 4-143 3.11e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 3.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643   4 GSIQQHLAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQPLWMNLARA 83
Cdd:TIGR02917 259 NSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASI 338

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  84 HRELGDSEAERAALEKVLTIDQRDLLALIRLAELHERLGEEALGAKRWGAVVALSSGIPD 143
Cdd:TIGR02917 339 QLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAA 398
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
9-74 3.33e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.69  E-value: 3.33e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1899467643   9 HLAEAQRAMHAGQVDKARHhLDAVIELDPTEPNARNALGLFALDQGDARAAAAHFEIACDRDPKAQ 74
Cdd:COG3063    29 LNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSAL 93
TPR_8 pfam13181
Tetratricopeptide repeat;
76-104 3.51e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 34.68  E-value: 3.51e-03
                          10        20
                  ....*....|....*....|....*....
gi 1899467643  76 LWMNLARAHRELGDSEAERAALEKVLTID 104
Cdd:pfam13181   3 AYYNLGLIYLKLGDYEEAKEYYEKALELD 31
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 10-140 9.10e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 37.97  E-value: 9.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1899467643  10 LAEAQRAMHAGQVDKARHHLDAVIELDPTEPNARnALGLfaLDQGDARAAAAHFEIACDRDPKAQPLWMNLARAHRELGD 89
Cdd:COG3071   197 AAYARALIALGDHDEAERLLREALKRQWDPRLVR-LYGR--LQGGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQL 273

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1899467643  90 SEAERAALEKVLTIDQrDLLALIRLAELHERLGEEALGAKRWGAVVALSSG 140
Cdd:COG3071   274 WGKAREYLEAALALRP-SAEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 45-107 9.66e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 34.62  E-value: 9.66e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1899467643  45 ALGLFALDQGDARAAAAHFEIACDRD---PKAQPLWMNLARAHRELGDSEAERAALEKVLTIDQRD 107
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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