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Conserved domains on  [gi|1897831847|gb|QNM39707|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Traulia lofaoshana]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 1.69e-23

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 85.59  E-value: 1.69e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  3 MFSILSSLMIYFAGVYIFSSKRKHLLMVLLSLEYIILSLFMLIVIFLIEFDYDYFFPVIFLVFSVCEGALGLSILVSMIR 82
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1897831847 83 SHGNDFFNS 91
Cdd:MTH00162  81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 1.69e-23

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 85.59  E-value: 1.69e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  3 MFSILSSLMIYFAGVYIFSSKRKHLLMVLLSLEYIILSLFMLIVIFLIEFDYDYFFPVIFLVFSVCEGALGLSILVSMIR 82
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1897831847 83 SHGNDFFNS 91
Cdd:MTH00162  81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-94 6.36e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 43.32  E-value: 6.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  4 FSILSSLMIYFAGVYIFSSkRKHLLMVLLSLEYIILSLFMLIVIFLIEFDYDY--FFPVIFLVFSVCEGALGLSILVSMI 81
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|...
gi 1897831847 82 RSHGNDFFNSFGL 94
Cdd:pfam00420 80 RTHGTDDVDSLNL 92
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 1.69e-23

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 85.59  E-value: 1.69e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  3 MFSILSSLMIYFAGVYIFSSKRKHLLMVLLSLEYIILSLFMLIVIFLIEFDYDYFFPVIFLVFSVCEGALGLSILVSMIR 82
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1897831847 83 SHGNDFFNS 91
Cdd:MTH00162  81 SHGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 6-97 9.35e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 61.14  E-value: 9.35e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  6 ILSSLMIYFAGVYIFSSKRKHLLMVLLSLEYIILSLFMLIVIFLIEFDYDYFFPVIFLVFSVCEGALGLSILVSMIRSHG 85
Cdd:MTH00188   6 ILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHG 85

                         90
                 ....*....|..
gi 1897831847 86 NDFFNSFGLTLC 97
Cdd:MTH00188  86 SDYVSSLNLIKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 4-97 8.14e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 58.70  E-value: 8.14e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  4 FSILSSLMIYFAGvyiFSSKRKHLLMVLLSLEYIILSLFMLIVIFLIEFDYDYFF--PVIFLVFSVCEGALGLSILVSMI 81
Cdd:MTH00125   6 FSLYTAFMLSLLG---LSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTpmPIILLTFSACEAGTGLALLVATT 82

                         90
                 ....*....|....*.
gi 1897831847 82 RSHGNDFFNSFGLTLC 97
Cdd:MTH00125  83 RTHGSDHLKNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 4-97 9.87e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 53.43  E-value: 9.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  4 FSILSSLMIYFAGVYIFsskRKHLLMVLLSLEYIILSLFMLIVIFLIEFDYDYF--FPVIFLVFSVCEGALGLSILVSMI 81
Cdd:MTH00126   6 FSFSSAFILGLMGLAFH---RTHLLSALLCLEGMMLSLFIALSLWALQLESTSFsaAPMLLLAFSACEASAGLALLVATA 82

                         90
                 ....*....|....*.
gi 1897831847 82 RSHGNDFFNSFGLTLC 97
Cdd:MTH00126  83 RTHGTDRLQNLNLLQC 98
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 1-97 1.53e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 52.93  E-value: 1.53e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  1 MYMFSILSSLMIYFAGVYIFSSKRKHLLMVLLSLEYIILSLFMLIVIFLIEFDYDYFFPVIFLVFSVCEGALGLSILVSM 80
Cdd:MTH00149   1 SMFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSL 80

                         90
                 ....*....|....*..
gi 1897831847 81 IRSHGNDFFNSFGLTLC 97
Cdd:MTH00149  81 IRLHGNDYVSSLSSLKF 97
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 14-97 3.72e-10

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 51.68  E-value: 3.72e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847 14 FAGVYIFSSKRKHLLMVLLSLEYIILSLFMLIVIFL-IEFDYDYFFPVIFLVFSVCEGALGLSILVSMIRSHGNDFFNSF 92
Cdd:MTH00013  13 FISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLmFANQVNGMLAIVLLTFGACEASLGLSLLVLMTRSYGNDMLKSL 92


                 ....*
gi 1897831847 93 GLTLC 97
Cdd:MTH00013  93 TSNKC 97
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-97 6.72e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 48.45  E-value: 6.72e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  1 MYMFSILSSLMIYFAGvyiFSSKRKHLLMVLLSLEYIILSLFMLIVIFLIEFDYDYFF--PVIFLVFSVCEGALGLSILV 78
Cdd:MTH00067   3 PTYFTFYSAFLLGLMG---LAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFslPMFMLTFSACEASTGLALMV 79

                         90
                 ....*....|....*....
gi 1897831847 79 SMIRSHGNDFFNSFGLTLC 97
Cdd:MTH00067  80 ATTRTHGTDHLKNLNLLQC 98
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 4-97 3.19e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 46.85  E-value: 3.19e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  4 FSILSSLMIYFAGVYIFsskRKHLLMVLLSLEYIILSLFML--IVIFLIEFDYDYFFPVIFLVFSVCEGALGLSILVSMI 81
Cdd:MTH00107   6 MNIMLAFTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMatLTILNTHFTLASMMPIILLVFAACEAAVGLALLVMVS 82

                         90
                 ....*....|....*.
gi 1897831847 82 RSHGNDFFNSFGLTLC 97
Cdd:MTH00107  83 NTYGTDYVQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-94 6.36e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 43.32  E-value: 6.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  4 FSILSSLMIYFAGVYIFSSkRKHLLMVLLSLEYIILSLFMLIVIFLIEFDYDY--FFPVIFLVFSVCEGALGLSILVSMI 81
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|...
gi 1897831847 82 RSHGNDFFNSFGL 94
Cdd:pfam00420 80 RTHGTDDVDSLNL 92
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 12-94 5.00e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 41.08  E-value: 5.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847 12 IYFAGVYIFSSKRKHLLMVLLSLEYIILSLFMLIVIFLIEFDY--DYFFPVIFLVFSVCEGALGLSILVSMIRSHGNDFF 89
Cdd:MTH00181   8 AFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSssMLMFGLILLTFSACEAVLGLSLLVATNRTHGSDHL 87


                 ....*
gi 1897831847 90 NSFGL 94
Cdd:MTH00181  88 LKFNL 92
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 3-94 3.24e-05

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 39.13  E-value: 3.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897831847  3 MFSILSSLMIYFAGVYIFSSKRKHLLMVLLSLEYIILSLFMLIVIFLIEFDYDYF--FPVIFLVFSVCEGALGLSILVSM 80
Cdd:MTH00043   2 NIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVLL 81

                         90
                 ....*....|....
gi 1897831847 81 IRSHGNDFFNSFGL 94
Cdd:MTH00043  82 SRNHNSDLVASLNL 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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