|
Name |
Accession |
Description |
Interval |
E-value |
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
3-379 |
0e+00 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 564.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 3 MHIDSLLAQGGNGKDAGTGAVSFPIYQSATFRHPAL--------GESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFS 74
Cdd:COG0626 1 MGPATRAVHAGRDPDPQTGAVSPPIYLTSTFVFPSAealaarfaGEEGGYIYSRYGNPTRRALEEALAALEGGEAALAFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 75 SGLAAITAVI-SLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKIT 153
Cdd:COG0626 81 SGMAAISAVLlALLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 154 DLREIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLG 233
Cdd:COG0626 161 DIAAIAAIAHAAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERLRFLQNALGAVLS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 234 PFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLH-DAGKVPEV 312
Cdd:COG0626 241 PFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKgGREAARRF 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897360700 313 LSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:COG0626 321 LDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLEDVDDLIADLEQALA 387
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
1-379 |
0e+00 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 558.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 1 MAMHIDSLLAQGGNGKDAGTGAVSFPIYQSATFRHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAI 80
Cdd:PRK08247 1 QMSTIETKLAQIGNRSDERTGTVNPPVYFSTAYRHEGIGESTGFDYSRTGNPTRGVLEQAIADLEGGDQGFACSSGMAAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 81 TAVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRR 160
Cdd:PRK08247 81 QLVMSLFRSGDELIVSSDLYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQETDIAAIAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 161 ICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLL 240
Cdd:PRK08247 161 IAKKHGLLLIVDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQELCERLAYYQNAAGAVLSPFDSWLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 241 VRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYigldnhPGRevhfqqasgpGGMISFTLHDAGKVPEVLSRIQLIS 320
Cdd:PRK08247 241 IRGMKTLALRMRQHEENAKAIAAFLNEQPGVTDVLY------PGR----------GGMLSFRLQDEEWVNPFLKSLKLIT 304
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1897360700 321 FAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK08247 305 FAESLGGVESFITYPATQTHADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQAFK 363
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
6-379 |
0e+00 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 537.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 6 DSLLAQGGNGKDAGTGAVSFPIYQSATFRHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVI- 84
Cdd:pfam01053 1 DTLAVHAGQRPDPQTGAVSVPIYLTSTYVFDFAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGMAAITAAIl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 85 SLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDD 164
Cdd:pfam01053 81 ALLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIEAIAKLAKK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 165 GGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGM 244
Cdd:pfam01053 161 HGILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEELGKELYFLQNATGAVLSPFDAWLLLRGL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 245 KTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLH-DAGKVPEVLSRIQLISFAE 323
Cdd:pfam01053 241 KTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFELKgGLEAAKKFLDNLKLFSLAV 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1897360700 324 SLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:pfam01053 321 SLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQALE 376
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
3-379 |
0e+00 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 508.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 3 MHIDSLLAQGGNGKDAGTGAVSFPIYQSATFRHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITA 82
Cdd:PRK07671 1 MRAKTKLIHGGIIGDPSTGAVSVPIYQVSTYKQEAVGKHQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 83 VISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRIC 162
Cdd:PRK07671 81 VMMLFSSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 163 DDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVR 242
Cdd:PRK07671 161 KEKGLLTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 243 GMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDAGKVPEVLSRIQLISFA 322
Cdd:PRK07671 241 GLKTLGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDVGSEETANKVLERLQYFTLA 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897360700 323 ESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK07671 321 ESLGAVESLISIPSQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQALA 377
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
21-379 |
5.98e-170 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 478.62 E-value: 5.98e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 21 GAVSFPIYQSATFRHPALGEST--------GFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVI-SLFGPGD 91
Cdd:cd00614 1 GAVAPPIYQTSTFVFPSPAEAAdlfalregGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTVLlALLKAGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 92 HLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIV 171
Cdd:cd00614 81 HVVASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEHGALLVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 172 DNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRL 251
Cdd:cd00614 161 DNTFATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 252 DRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTL-HDAGKVPEVLSRIQLISFAESLGGVES 330
Cdd:cd00614 241 ERHSENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELkGGLEAAKKFLNALKLFSLAVSLGGVES 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1897360700 331 LLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:cd00614 321 LVEHPASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQALK 369
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
1-379 |
3.44e-166 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 469.90 E-value: 3.44e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 1 MAMHIDSLLAQGGNGKDAGTGAVSFPIYQSATFRHPALGE-STGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAA 79
Cdd:PRK07811 9 ANQGFATRAIHAGYEPDPATGAVNPPIYASSTFAQDGVGGlRGGYEYARTGNPTRTALEEQLAALEGGAYGRAFSSGMAA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 80 ITAVI-SLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREI 158
Cdd:PRK07811 89 TDCLLrAVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVETPTNPLLSITDIAAL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 159 RRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSW 238
Cdd:PRK07811 169 AELAHDAGAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFLQNGAGAVPGPFDAY 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 239 LLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDAGKVP-EVLSRIQ 317
Cdd:PRK07811 249 LTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRLAGGEEAArDFCARTK 328
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897360700 318 LISFAESLGGVESLLTFPARQTHG-------DIPEDirrrcgvtdcLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK07811 329 VFTLAESLGGVESLIEHPSAMTHAstagsqlEVPDD----------LVRLSVGIEDVADLLADLEQALG 387
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
3-379 |
1.20e-162 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 460.90 E-value: 1.20e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 3 MHIDSLLAQGGNGKDAGTGAVSFPIYQSATFRHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITA 82
Cdd:PRK06176 1 MRMQTKLIHGGISEDTTTGAVSVPIYQTSTYRQDAIGRPKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 83 VISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRIC 162
Cdd:PRK06176 81 VFSLFQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 163 DDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVR 242
Cdd:PRK06176 161 KDHGLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 243 GMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDAGKVPEVLSRIQLISFA 322
Cdd:PRK06176 241 GIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVESLKLFILG 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897360700 323 ESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK06176 321 ESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFA 377
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
1-379 |
1.99e-153 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 437.67 E-value: 1.99e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 1 MAMH--IDSLLAQGGNGKDAGTGAVSFPIYQSATFRHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLA 78
Cdd:PRK08064 1 MAMSysIDTLLLHNQYKHDKQTGAVNVPIYHASTFHQFDFDTFGKYDYSRSGNPTREALEDIIAELEGGTKGFAFASGMA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 79 AITAVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREI 158
Cdd:PRK08064 81 AISTAFLLLSKGDHVLISEDVYGGTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSNPLLKVTDIRGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 159 RRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSW 238
Cdd:PRK08064 161 VKLAKAIGCLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGLAVVKDEELAQKLYFLQNSFGAVLGVQDCW 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 239 LLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDAGKVPEVLSRIQL 318
Cdd:PRK08064 241 LVLRGLKTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATSAGAVLSFTLQSEEAVRQFVSHVKL 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897360700 319 ISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK08064 321 PVFAVSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALS 381
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
1-378 |
3.65e-138 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 398.04 E-value: 3.65e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 1 MAMHIDSLLAQGGNGKDAGTGAVSFPIYQSATFRHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAI 80
Cdd:PRK07269 3 KDLHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGQSTGFDYTRTKNPTRAKLEETLAAIESADYALATSSGMSAI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 81 TAVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSdpEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRR 160
Cdd:PRK07269 83 VLAFSVFPVGSKVVAVRDLYGGSFRWFNQQEKEGRFHFTYANTE--EELIAAIEEDTDIVYIETPTNPLMVEFDIEKVAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 161 ICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLL 240
Cdd:PRK07269 161 LAHAKGAKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLAGVVVTNDLELYEKLFYNLNTTGAVLSPFDSYLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 241 VRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYigldnhpgrevhfqqaSGPGGMISFTLHDAGKVPEVLSRIQLIS 320
Cdd:PRK07269 241 MRGLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLY----------------TGKGGMISFKVADETRIPHILNSLKVFT 304
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1897360700 321 FAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQAL 378
Cdd:PRK07269 305 FAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLKQAL 362
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
5-379 |
7.13e-138 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 397.66 E-value: 7.13e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 5 IDSLLAQGGNGKDAgTGAVSFPIYQSATFRHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVI 84
Cdd:TIGR01329 1 LSTLLVNTDNKNDP-YDASSMPIYQTATFKQPLAIENGPYDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMAALDVIT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 85 SLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDD 164
Cdd:TIGR01329 80 RLLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIRKISEMAHA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 165 GGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGM 244
Cdd:TIGR01329 160 QNALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLAVKGEEIAKKVYFLQNSTGSGLAPFDCWLLLRGI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 245 KTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDAGKVPEVLSRIQLISFAES 324
Cdd:TIGR01329 240 KTLAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKGAGSVLSFETGSVALSKRLVEATKLFSITVS 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1897360700 325 LGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:TIGR01329 320 FGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAFV 374
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
22-378 |
5.07e-130 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 380.91 E-value: 5.07e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 22 AVSFPIYQSATFRHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVISLFGPGDHLILCEDLYG 101
Cdd:PLN02509 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYG 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 102 GTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIVDNTFISPYLQ 181
Cdd:PLN02509 183 GSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIAEMAHAQGALVLVDNSIMSPVLS 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 182 RPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRLDRAQENASAI 261
Cdd:PLN02509 263 RPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKI 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 262 ARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDAGKVPEVLSRIQLISFAESLGGVESLLTFPARQTHG 341
Cdd:PLN02509 343 AMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHA 422
|
330 340 350
....*....|....*....|....*....|....*..
gi 1897360700 342 DIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQAL 378
Cdd:PLN02509 423 SIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
21-378 |
1.54e-122 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 359.20 E-value: 1.54e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 21 GAVSFPIYQSATFRHPAL--------GESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITA-VISLFGPGD 91
Cdd:TIGR01328 20 GALTPPIYQTSTFVFDSCeqggnrfaGQESGYIYSRLGNPTVSNLEGRIAFLEGTEAAVATSSGMGAIAAtLLTILKAGD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 92 HLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIV 171
Cdd:TIGR01328 100 HLISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKLIDMERVCRDAHSQGVKVIV 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 172 DNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGD-KLAFYQNASGAVLGPFDSWLLVRGMKTLGLR 250
Cdd:TIGR01328 180 DNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQiRMVGIKDMTGSVISPFDAWLILRGLKTLNIR 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 251 LDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTL---HDAGKvpEVLSRIQLISFAESLGG 327
Cdd:TIGR01328 260 MKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGHDIAAKQMRMGGGMITFELkggFAGAK--KLLNNLKLIRLAVSLGD 337
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1897360700 328 VESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQAL 378
Cdd:TIGR01328 338 AETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDLIADLKQAL 388
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
21-378 |
1.69e-121 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 356.46 E-value: 1.69e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 21 GAVSFPIYQSATFRHPAL--------GESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAV-ISLFGPGD 91
Cdd:PRK06767 22 GSLTPPLFQTSTFTFETAqqgeasfaGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEALAFGSGMAAISATlIGFLKAGD 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 92 HLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIV 171
Cdd:PRK06767 102 HIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTMKLIDLKQVIRVAKRNGLLVIV 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 172 DNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRL 251
Cdd:PRK06767 182 DNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDIGGIMAPFDAWLLLRGLKTLAVRM 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 252 DRAQENASAIARWLASHPAVDQVYYigldnhPGREVHFQQASGPGGMISFTLhDAGK--VPEVLSRIQLISFAESLGGVE 329
Cdd:PRK06767 262 DRHCDNAEKIVSFLKNHDAVEGVWY------PEGELASRQMKRGGGVISFSI-KGGKeeTQAFINDLHFITIAVSLGDTE 334
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1897360700 330 SLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQAL 378
Cdd:PRK06767 335 TLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQAL 383
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
3-379 |
4.95e-121 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 356.65 E-value: 4.95e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 3 MHIDSLLAQGGNGKDAGTGAVSFPIYQSATFRHP---------ALGEStGFDYSRSGNPTRQVLEELIAKLEGGRRGLAF 73
Cdd:COG2873 6 YGFETLALHAGQEPDPTTGARAVPIYQTTSYVFDdaehaadlfALKEP-GNIYTRIMNPTTDVLEKRIAALEGGVAALAT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 74 SSGLAAIT-AVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKI 152
Cdd:COG2873 85 ASGQAAITlAILNLAEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNPALDV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 153 TDLREIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAV---------AAR--------- 214
Cdd:COG2873 165 LDIEAIAEIAHEHGVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIVdggnfdwaaNGKfpeltepdp 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 215 --------EDLGDkLAF-------YQNASGAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGL 279
Cdd:COG2873 245 syhglvytEAFGN-AAFitkarvqLLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWVNYPGL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 280 DNHPGREVhfqqAS-----GPGGMISFTL---HDAGKvpEVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRC 351
Cdd:COG2873 324 PSHPYHEL----AQkylpkGAGGVLTFGLkggREAGK--KFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAA 397
|
410 420
....*....|....*....|....*...
gi 1897360700 352 GVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:COG2873 398 GVTPDLIRLSVGIEDIDDIIADLDQALA 425
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
12-378 |
1.00e-118 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 349.90 E-value: 1.00e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 12 GGNGKDAGTGAVSFPIYQSATF---------RHPAlGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITA 82
Cdd:PRK06234 16 GGHIGDKQFGSLATPIYQTSTFifdsaeqggRRFA-GEESGYIYSRLGNPTSTEVENKLALLEGGEAAVVAASGMGAISS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 83 VI-SLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRI 161
Cdd:PRK06234 95 SLwSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLKVTDIKAISNI 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 162 CDDG--GLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAaREDLGDKLAFY--QNASGAVLGPFDS 237
Cdd:PRK06234 175 AHENnkECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVG-KEEFINQVKLFgiKDMTGSVIGPFEA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 238 WLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLH---DAGKVpeVLS 314
Cdd:PRK06234 254 FLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELKggvEEGKV--VMN 331
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897360700 315 RIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQAL 378
Cdd:PRK06234 332 NVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQAL 395
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
21-378 |
9.86e-116 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 341.66 E-value: 9.86e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 21 GAVSFPIYQSATFRHP--ALGESTGFD--YSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAV-ISLFGPGDHLIL 95
Cdd:PRK08574 18 GSLQPPIYLTALFRQEgeAYPSDRGFDlkYSREENPTLRPLEEALAKLEGGVDALAFNSGMAAISTLfFSLLKAGDRVVL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 96 CEDLYGGTYRLLEQVfRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIVDNTF 175
Cdd:PRK08574 98 PMEAYGTTLRLLKSL-EKFGVKVVLAYPSTEDIIEAIKEGRTKLVFIETMTNPTLKVIDVPEVAKAAKELGAILVVDNTF 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 176 ISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRLDRAQ 255
Cdd:PRK08574 177 ATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAVAWSGEFLEELWEWRRRLGTIMQPFEAYLVLRGLKTLEVRFERQC 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 256 ENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGP--GGMISFTLHDAGK-VPEVLSRIQLISFAESLGGVESLL 332
Cdd:PRK08574 257 RNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKRLFGKDlyGGVVSFRVKGGRDaVLKFLRSLKLIKPSPSLGGVESLA 336
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1897360700 333 TFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQAL 378
Cdd:PRK08574 337 TYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDLDQAL 382
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
21-379 |
1.04e-115 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 342.17 E-value: 1.04e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 21 GAVSFPIYQSATFRHPAL--------GESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVI-SLFGPGD 91
Cdd:PRK07503 26 GALVPPVYLTATFAFPTAeygaecfaGEEEGHFYSRISNPTLALLEQRMASLEGGEAAVALASGMGAITATLwTLLRPGD 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 92 HLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIV 171
Cdd:PRK07503 106 EVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRLVDIAAVAEIAHGAGAKVVV 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 172 DNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGD-KLAFYQNASGAVLGPFDSWLLVRGMKTLGLR 250
Cdd:PRK07503 186 DNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRiRLEGLKDMTGAVMSPFDAFLLMRGLKTLALR 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 251 LDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTL---HDAGKvpEVLSRIQLISFAESLGG 327
Cdd:PRK07503 266 MDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELkggIAAGR--RFMNALQLFARAVSLGD 343
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1897360700 328 VESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK07503 344 AESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALD 395
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
21-379 |
7.31e-110 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 327.08 E-value: 7.31e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 21 GAVSFPIYQSATFRHP--------ALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVISLF-GPGD 91
Cdd:PRK08249 25 GATQVPVVLSVAYGYDdidewydvALGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFSTGMAAISNTLYTFlKPGD 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 92 HLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIV 171
Cdd:PRK08249 105 RVVSIKDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIVDIERLAAAAKKVGALVVV 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 172 DNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAArEDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRL 251
Cdd:PRK08249 185 DNTFATPINQNPLALGADLVIHSATKFLSGHADALGGVVCGS-KELMEQVYHYREINGATMDPMSAYLILRGMKTLKLRV 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 252 DRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLhdAGKVPEV---LSRIQLISFAESLGGV 328
Cdd:PRK08249 264 RQQQESAMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVL--KGGMDTVkrlLPKLRYAHRAANLGAV 341
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1897360700 329 ESLLTfPARQT-HGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK08249 342 ETIYG-PARTTsHVENTLEERAALGIPEGLVRISVGIEDTEDLIADLEQAFA 392
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
11-379 |
9.77e-110 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 327.33 E-value: 9.77e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 11 QGGNGKDAGTGAVSFPIYQSATFRHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVI-SLFGP 89
Cdd:PRK08776 19 RAGIDRDTAYGAVTPPIVLSSNFSFDGFGNKRQYDYTRSGNPTRDLLGEALAELEGGAGGVITATGMGAINLVLnALLQP 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 90 GDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLL 169
Cdd:PRK08776 99 GDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNPLLRITDLRFVIEAAHKVGALT 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 170 IVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGL 249
Cdd:PRK08776 179 VVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVARDAELHQQLVWWANALGLTGSPFDAFLTLRGLRTLDA 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 250 RLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLhdAGKVPEV---LSRIQLISFAESLG 326
Cdd:PRK08776 259 RLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFEL--EGGEAAVrafVDGLRYFTLAESLG 336
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1897360700 327 GVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK08776 337 GVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRAGLA 389
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
15-379 |
3.51e-108 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 322.17 E-value: 3.51e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 15 GKDAGTGAVSFPIYQSATFRHPAlGEStgFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAI-TAVISLFGPGDHL 93
Cdd:PRK06460 11 DIDEATGAITTPIYQTTAYHYPE-GEK--YRYSREANPTVLELTKKIVELENAEMGVAFSSGMGAIsTTALALLKPGNSV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 94 ILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIVDN 173
Cdd:PRK06460 88 LVHRDMFGRSYRFFTDYLKNWGVNVDASNPGSDNIIEKAKSKRYDVVFVENITNPLLRVVDITELSKVCKENGSILIVDA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 174 TFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAvAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRLDR 253
Cdd:PRK06460 168 TFSTPINQKPLELGADIVVHSASKFLAGHNDVIAGLA-AGYGKLLNVIDQMRRTLGTSLDPHAAYLTLRGIKTLKIRMDV 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 254 AQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLH-DAGKVPEVLSRIQLISFAESLGGVESLL 332
Cdd:PRK06460 247 INRNAEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVNgGQESALKVMKSLKLIIPAQTLGGVNSVI 326
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1897360700 333 TFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK06460 327 SHPATMSHRTLSLEERKIVGITDSLLRLSVGIEDVNDLIEDLDRALS 373
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
13-378 |
5.50e-106 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 316.84 E-value: 5.50e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 13 GNGKDAGTGAVSFPIYQSATFRHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVISLF-GPGD 91
Cdd:PRK08045 13 GLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFlKPGD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 92 HLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIV 171
Cdd:PRK08045 93 LLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAREAGAVSVV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 172 DNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRL 251
Cdd:PRK08045 173 DNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRM 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 252 DRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLH-DAGKVPEVLSRIQLISFAESLGGVES 330
Cdd:PRK08045 253 ELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDgDEQTLRRFLGGLSLFTLAESLGGVES 332
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1897360700 331 LLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQAL 378
Cdd:PRK08045 333 LISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGF 380
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
39-379 |
3.53e-104 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 312.32 E-value: 3.53e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 39 GESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITA-VISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLT 117
Cdd:PRK08133 48 GEEPGNIYSRFTNPTVTMFQERLAALEGAEACVATASGMAAILAvVMALLQAGDHVVSSRSLFGSTVSLFEKIFARFGIE 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 118 ADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTK 197
Cdd:PRK08133 128 TTFVDLTDLDAWRAAVRPNTKLFFLETPSNPLTELADIAALAEIAHAAGALLVVDNCFCTPALQQPLKLGADVVIHSATK 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 198 YLGGHNDVVAGlAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYI 277
Cdd:PRK08133 208 YLDGQGRVLGG-AVVGSKELMEEVFGFLRTAGPTLSPFNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYP 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 278 GLDNHPGREVHFQQASGPGGMISFTLHDAGKVP-EVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDC 356
Cdd:PRK08133 287 GLPSHPQHELAKRQQKGGGAIVSFEVKGGREAAwRVIDATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEG 366
|
330 340
....*....|....*....|...
gi 1897360700 357 LLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK08133 367 LIRVAVGLEDVADIKADLARGLA 389
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
39-378 |
3.23e-103 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 309.47 E-value: 3.23e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 39 GESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAI-TAVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLT 117
Cdd:TIGR01325 41 GELPGFVYSRYGNPTVSVFEERLALLEGAEAAVATASGMAAIfAALMALLGAGDHVVASRSLFGSCFVVCSEILPRFGVQ 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 118 ADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTK 197
Cdd:TIGR01325 121 TVFVDGTDLSAWEAALKPNTKAVFVETPSNPLQELVDIAAVAELAHAAGAKVVVDNVFATPLLQQPLKLGADVVVYSATK 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 198 YLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYI 277
Cdd:TIGR01325 201 HIDGQGRVLGGAILGSEEYMDEPVQKLLRHTGPAMSPFNAWVLLKGLETLAIRVQHQNASALAIAEWLNGHPSVQWVYYP 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 278 GLDNHPGREVHFQQASGPGGMISFTLHDAGKVPEVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCL 357
Cdd:TIGR01325 281 GLPSHPQHELAKRQMSGGGTVVTFDLDCRQAAFKVLDAMRLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGDGL 360
|
330 340
....*....|....*....|.
gi 1897360700 358 LRLSVGIENVHDLIDDLAQAL 378
Cdd:TIGR01325 361 VRLSVGLEDVDDLIADIDRAL 381
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
17-379 |
5.83e-103 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 309.13 E-value: 5.83e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 17 DAGTGAVSFPIYQSATFRHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVIS-LFGPGDHLIL 95
Cdd:PRK08861 18 DSQYHAVVPPIYLSTNYGFPAFGEVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVTNCGTSALNLWVSaLLGPDDLIVA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 96 CEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIVDNTF 175
Cdd:PRK08861 98 PHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDIAELCQKAKAVGALVAVDNTF 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 176 ISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRLDRAQ 255
Cdd:PRK08861 178 LTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTKEHAEELAWWGNCIGATGTPFDSYMTLRGIRTLGARMRVHE 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 256 ENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDAGKVPEV-LSRIQLISFAESLGGVESLLTF 334
Cdd:PRK08861 258 ESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFAGSFEQLKVfVKALALFSLAESLGGVESLICH 337
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1897360700 335 PARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK08861 338 PASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLIADLDQAFA 382
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
4-379 |
2.01e-101 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 306.21 E-value: 2.01e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 4 HIDSLLAQGGNGKDAGTGAVSFPIYQ--SATFRHPALG------ESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSS 75
Cdd:TIGR01326 1 HFETLQLHAGQEPDPTTGSRAVPIYQttSYVFDSTEHAaalfglQEPGNIYSRLMNPTTDVLEQRIAALEGGVAALAVAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 76 GLAAIT-AVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITD 154
Cdd:TIGR01326 81 GQAAITyAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINVLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 155 LREIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAA--------------------- 213
Cdd:TIGR01326 161 IEAIAEVAHRHGIPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVDGgkfdwnngrfplfttpdpsyh 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 214 ----REDLGDkLAFYQNA-------SGAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNH 282
Cdd:TIGR01326 241 glvfTETLGN-PAFILKArvqllrdLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGLASH 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 283 PGREVhFQQ--ASGPGGMISFTL---HDAGKvpEVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCL 357
Cdd:TIGR01326 320 PHHAL-AKKylPKGFGAVLSFEIkggREAGK--KFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGL 396
|
410 420
....*....|....*....|..
gi 1897360700 358 LRLSVGIENVHDLIDDLAQALA 379
Cdd:TIGR01326 397 IRLSVGIENIDDIIADLEQALE 418
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
11-378 |
1.80e-97 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 294.89 E-value: 1.80e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 11 QGGNGKDAGTGAVSFPIYQSATFRHP-----ALGESTG---FDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITA 82
Cdd:PRK06434 15 QSGELRDPRFGNVTTPIFETSTFVYPnsekeAYMDSTRgmpYIYTRWGNPTVQAFEEKYAVLENAEHALSFSSGMGAITS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 83 VI-SLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTsdpEQVNAA--VTSRTKAIFIETPTNPTMKITDLREIR 159
Cdd:PRK06434 95 AIlSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDT---DRLNSLdfDPSNYDLIYAESITNPTLKVPDIKNVS 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 160 RICDdgGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWL 239
Cdd:PRK06434 172 SFCH--ENDVIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGTNNKSIFNNLVERRKTLGSNPDPIQAYL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 240 LVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYigldnhPGREVHFQQASGPGGMISFTLHDAGKVPEVLSRIQLI 319
Cdd:PRK06434 250 ALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYY------PDTEIGKKVLRGFGGMLSFELRSMEDVHKFIRNLEIP 323
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1897360700 320 SFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQAL 378
Cdd:PRK06434 324 MVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENAL 382
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
21-378 |
5.11e-96 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 292.73 E-value: 5.11e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 21 GAVSFPIYQSATF------------------RHPALGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAI-T 81
Cdd:PRK07049 34 GAVKPPVFLTSTFvfrsaedgrdffdyvsgrKEPPAGEGAGLVYSRFNHPNSEIVEDRLAVYEGAESAALFSSGMSAIaT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 82 AVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTA-DYVNTSDPEQVNAAVTS-----RTKAIFIETPTNPTMKITDL 155
Cdd:PRK07049 114 TLLAFVRPGDVILHSQPLYGGTETLLAKTFRNFGVGAvGFADGLSEAAIGAAAEAaaakgRVSLILIETPANPTNSLVDV 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 156 REIRRICD-----DGGLLLIV-DNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGlAVAAREDLGDKLAFYQNASG 229
Cdd:PRK07049 194 AAVRRVADaiearQGHRPIIAcDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAG-AVLGRKALIRQVRALRSAIG 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 230 AVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGL--DNHPGREVHFQQASGPGGMISFTLhdAG 307
Cdd:PRK07049 273 TQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHYLPFldPDSAYGAVYKRQCTGAGSTFSFDI--KG 350
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897360700 308 KVPEV---LSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQAL 378
Cdd:PRK07049 351 GQAAAfrfLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHPDDLIADLAQAL 424
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
23-379 |
5.88e-92 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 280.34 E-value: 5.88e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 23 VSFPIYQSATFrHPALGESTGFD-YSRSGNPTRQVLEELIAKLEGGRrGLAFSSGLAAITAVI-SLFGPGDHLILCEDLY 100
Cdd:PRK07582 22 VLPGPVFAAPY-HLSPGEPTGPDtYGRASNPTWRALEAALGELEGAE-ALVFPSGMAAITAVLrALLRPGDTVVVPADGY 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 101 GGTYRLLEQVFRPWGLTADYVNTSDPEQvnaAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIVDNTFISPYL 180
Cdd:PRK07582 100 YQVRALAREYLAPLGVTVREAPTAGMAE---AALAGADLVLAETPSNPGLDVCDLAALAAAAHAAGALLVVDNTTATPLG 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 181 QRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRLDRAQENASA 260
Cdd:PRK07582 177 QRPLELGADLVVASDTKALTGHSDLLLGYVAGRDPELMAAVERWRLLAGAIPGPFEAWLAHRSLGTLGLRFARQCANALA 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 261 IARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDAGKVPEVLSRIQLISFAESLGGVESllTFPARQTH 340
Cdd:PRK07582 257 VAELLAGHPAVRGVRYPGLPGDPAHEVAARQMRRFGGLVSFELADAAAAERFVAASRLVVAATSFGGVHT--SADRRARW 334
|
330 340 350
....*....|....*....|....*....|....*....
gi 1897360700 341 GDipedirrrcGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK07582 335 GD---------AVPEGFVRLSCGIEDTDDLVADLERALD 364
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
5-379 |
7.91e-90 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 276.98 E-value: 7.91e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 5 IDSLLAQGGNGKDAGTGAVSFPIYQSATF-----RHPA--LG-ESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSG 76
Cdd:PRK05994 8 FATLAVHAGAQPDPTTGARATPIYQTTSFvfndaDHAAslFGlQAFGNIYTRITNPTNAVLEERVAALEGGTAALAVASG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 77 LAAITAVI-SLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDL 155
Cdd:PRK05994 88 HAAQFLVFhTLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTVTDI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 156 REIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAA---------------------- 213
Cdd:PRK05994 168 AAIAEVAHRAGLPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIIVDGgtfdwsksgkypmlseprpeyh 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 214 ----REDLGDkLAFYQNAS-------GAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNH 282
Cdd:PRK05994 248 glvlHETFGN-FAFAIAARvlglrdlGPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGLPDD 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 283 PGREVHFQQA-SGPGGMISFTLH---DAGKvpEVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLL 358
Cdd:PRK05994 327 PYHALAQKYSpKGAGAVFTFGLKggyEAGV--KLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVV 404
|
410 420
....*....|....*....|.
gi 1897360700 359 RLSVGIENVHDLIDDLAQALA 379
Cdd:PRK05994 405 RLSIGIEDVDDIIADLEQALA 425
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
5-379 |
9.86e-90 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 276.72 E-value: 9.86e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 5 IDSLLAQGGNGKDAGTGAVSFPIYQSATF-----RHPA----LGEStGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSS 75
Cdd:PRK08248 9 LETLAIHAGQEIDPTTGSRAVPIYQTTSYgfrdsEHAAnlfsLKEF-GNIYTRIMNPTTDVFEKRIAALEGGIGALAVSS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 76 GLAAIT-AVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITD 154
Cdd:PRK08248 88 GQAAITySILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGNPKGDVLD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 155 LREIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAV-AAREDLGDKLAF---------- 223
Cdd:PRK08248 168 IEAVAAIAHEHGIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVdSGKFDWKGSGKFpgltepdpsy 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 224 ----YQNAS-----------------GAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNH 282
Cdd:PRK08248 248 hglvYTDAVgeaayitkarvqllrdlGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSYPGLPSH 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 283 PGREVHFQQ-ASGPGGMISFTLH---DAGKvpEVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLL 358
Cdd:PRK08248 328 PSYELAKKYlPKGQGAILTFGIKggvEAGK--KLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVTPGLV 405
|
410 420
....*....|....*....|.
gi 1897360700 359 RLSVGIENVHDLIDDLAQALA 379
Cdd:PRK08248 406 RLSVGTEAIDDILDDLRQAIR 426
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
13-379 |
5.44e-89 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 275.09 E-value: 5.44e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 13 GNGKDAGTGAVSFPIYQ--SATFR---HPA----LGEsTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAIT-A 82
Cdd:PRK07812 22 GQTPDPATNARALPIYQttSYTFDdtdHAAalfgLAE-PGNIYTRIMNPTQDVVEQRIAALEGGVAALLLASGQAAETfA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 83 VISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYV-NTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRI 161
Cdd:PRK07812 101 ILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKLGIEVSFVeDPDDLDAWRAAVRPNTKAFFAETISNPQIDVLDIPGVAEV 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 162 CDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAV------------------------AAREDL 217
Cdd:PRK07812 181 AHEAGVPLIVDNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIVdggtfdwtqgrfpgfttpdpsyhgVVFAEL 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 218 GDKlAFYQNAS-------GAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQ 290
Cdd:PRK07812 261 GPP-AYALKARvqllrdlGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGLPSSPWYERAKR 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 291 QA-SGPGGMISFTLH---DAGKvpEVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGIEN 366
Cdd:PRK07812 340 LApKGTGAVLSFELAggvEAGK--AFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLVRLAVGIEG 417
|
410
....*....|...
gi 1897360700 367 VHDLIDDLAQALA 379
Cdd:PRK07812 418 IDDILADLEAGFA 430
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
21-379 |
2.94e-87 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 268.87 E-value: 2.94e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 21 GAVSFPIYQSATFRHPAL--------GESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITA-VISLFGPGD 91
Cdd:PRK05968 24 DAVVPPIFQTSLFTFDSYdemedvyaGEKVRPIYSRGDNPTVRAFEEMLAKLEGAEDARGFASGMAAISStVLSFVEPGD 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 92 HLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSrTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIV 171
Cdd:PRK05968 104 RIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEAVAKALPG-AKLLYLESPTSWVFELQDVAALAALAKRHGVVTMI 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 172 DNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRL 251
Cdd:PRK05968 183 DNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVVAGSKEHIARINAEAYPYLGAKLSPFEAWLLLRGLRTLPLRM 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 252 DRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHfqqasGPGGMISFTLHDAGKVPEVLSRIQLISFAESLGGVESL 331
Cdd:PRK05968 263 KAHEASALEIARRLKAHPVVERVCHPALANHPPAGLS-----GTSGLFSFIFREGIDVRAFADALKLFRLGVSWGGHESL 337
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1897360700 332 LTfPARQTHGDIPE-DIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK05968 338 VV-PAEVVLQQKAQpNSAARFGVSPRSVRLHVGLEGTEALWADLEQALA 385
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
27-379 |
2.50e-83 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 259.28 E-value: 2.50e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 27 IYQSATFRHPAL-GESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAI-TAVISLFGPGDHLILCEDLYGGTY 104
Cdd:PRK07810 44 VYESAAAAEAAFtGELDRFVYSRYGNPTVSMFEERLRLIEGAEACFATASGMSAVfTALGALLGAGDRLVAARSLFGSCF 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 105 RLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIVDNTFISPYLQRPI 184
Cdd:PRK07810 124 VVCNEILPRWGVETVFVDGEDLSQWEEALSVPTQAVFFETPSNPMQSLVDIAAVSELAHAAGAKVVLDNVFATPLLQRGL 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 185 ECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARW 264
Cdd:PRK07810 204 PLGADVVVYSGTKHIDGQGRVLGGAILGDREYIDGPVQKLMRHTGPALSAFNAWVLLKGLETLALRVRHSNASALRIAEF 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 265 LASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDAGKVP-----EVLSRIQLISFAESLGGVESLLTFPARQT 339
Cdd:PRK07810 284 LEGHPAVRWVRYPFLPSHPQYDLAKRQMSGGGTVVTFELDAPEDAAkkrafEVLDKLRVIDISNNLGDAKSLITHPATTT 363
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1897360700 340 HGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK07810 364 HRAMGPEGRAAIGLGDGVVRLSVGLEDTDDLIADLDRALG 403
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
21-379 |
2.18e-82 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 256.92 E-value: 2.18e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 21 GAVSFPIYQSATFRHPAL--------GESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVI-SLFGPGD 91
Cdd:PRK05939 8 GAVHKPIHTSVTYGYEDArdlidvfqGKKPGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVFlTLLRAGD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 92 HLILCEDLYGGTYRLLEQVfRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIV 171
Cdd:PRK05939 88 HLVSSQFLFGNTNSLFGTL-RGLGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERGLLYVV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 172 DNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGlavaAREDLG--DKLAF------YQNAS--------------- 228
Cdd:PRK05939 167 DNTMTSPWLFRPKDVGASLVINSLSKYIAGHGNALGG----AVTDTGlfDWSAYpnifpaYRKGDpqqwgltqirkkglr 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 229 --GAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDA 306
Cdd:PRK05939 243 dmGATLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLSFELADG 322
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1897360700 307 GKVPEVLSRIQLISFAESLGGVESLLtFPARQT--HGDIPEDiRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK05939 323 IDCFDFLNRLKLVIKATHLGDTRTLV-IPVAPTiyYEMGAER-RASMGIADSLIRVSVGIEDEADLIADFEQALD 395
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
39-379 |
4.25e-79 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 248.52 E-value: 4.25e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 39 GESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVI-SLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLT 117
Cdd:PRK07504 52 GEDPGFIYSRYSNPTVDMFEKRMCALEGAEDARATASGMAAVTAAIlCQVKAGDHVVAARALFGSCRYVVETLLPRYGIE 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 118 ADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTK 197
Cdd:PRK07504 132 STLVDGLDLDNWEKAVRPNTKVFFLESPTNPTLEVIDIAAVAKIANQAGAKLVVDNVFATPLFQKPLELGAHIVVYSATK 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 198 YLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYI 277
Cdd:PRK07504 212 HIDGQGRCLGGVVLSDKAWIEEHLQDYFRHTGPSLSPFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVIYP 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 278 GLDNHPGREVHFQQASGPGGMISFTLhDAGKVP--EVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTD 355
Cdd:PRK07504 292 GRADHPQADIIAKQMTGGSTLVAFEL-KGGKEAafRFLNALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELGISE 370
|
330 340
....*....|....*....|....
gi 1897360700 356 CLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK07504 371 GFLRLSAGLEDTDDLIEDLAAALK 394
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
3-379 |
4.03e-78 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 246.74 E-value: 4.03e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 3 MHIDSLLAQGGNGKDAGTGAVSFPIYQSATF-----RHPAlgesTGFD-------YSRSGNPTRQVLEELIAKLEGGRRG 70
Cdd:PRK06084 1 MKLETLAIHAGYSPDPTTKAVAVPIYQTTSYafddtQHGA----DLFDlkvpgniYTRIMNPTNDVLEQRVAALEGGVGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 71 LAFSSGLAAIT-AVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPT 149
Cdd:PRK06084 77 LAVASGMAAITyAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 150 MKITDLREIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAARE----DLGDKLAF-- 223
Cdd:PRK06084 157 GNIIDIQALADAAHRHGVPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVVDSGKfpwaEHKERFALln 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 224 -----YQNAS----------------------GAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYY 276
Cdd:PRK06084 237 tpdpsYHGVTyteafgpaafigrcrvvplrnmGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 277 IGLDNHPGREVHFQQASG-PGGMISFTLH---DAGKvpEVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCG 352
Cdd:PRK06084 317 AGLPDHPEHELARRYMGGkPASILSFGIKggqAAGA--RFIDALKLVVRLVNIGDAKSLACHPASTTHRQLNDEELEKAG 394
|
410 420
....*....|....*....|....*..
gi 1897360700 353 VTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK06084 395 VSRDMVRLSIGIEHIDDIIADLAQALD 421
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
6-378 |
3.68e-77 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 244.65 E-value: 3.68e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 6 DSLLAQGGNGKDAGTGAVSFPIYQSATF-----RHPAL---GESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGL 77
Cdd:PRK08134 10 DTLALHAGAAPDPATGARAVPIHLTTSFvfrdsDHAAAlfnLERAGHVYSRISNPTVAVLEERVAALEGGVGAIATASGQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 78 AAIT-AVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLR 156
Cdd:PRK08134 90 AALHlAIATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVLDIP 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 157 EIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAV------------------------- 211
Cdd:PRK08134 170 TVAAIAHEAGVPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLVdggrfdweasgkfpeltepyagfhg 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 212 ---------------AAREDLGDklafyqnaSGAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYY 276
Cdd:PRK08134 250 mvfaeestvaafllrARREGLRD--------FGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAH 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 277 IGLDNHPGREVHFQ-QASGPGGMISFTL---HDAGKvpEVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCG 352
Cdd:PRK08134 322 PELESHPDHALAKRlLPRGAGSVFSFDLkggRAAGR--KFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAG 399
|
410 420
....*....|....*....|....*.
gi 1897360700 353 VTDCLLRLSVGIENVHDLIDDLAQAL 378
Cdd:PRK08134 400 IGEGTIRLSIGLEDADDLIDDLKRAL 425
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
13-379 |
3.74e-68 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 221.28 E-value: 3.74e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 13 GNGKDAGTGAVSFPIYQSATF-----RHPALG---ESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVI 84
Cdd:PRK05613 22 GQSVDSDTSARNLPIYQTTSYvfdsaEHAKQRfalEDLGPIYSRLTNPTVEALENRIASLEGGVHAVAFASGQAAETAAI 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 85 -SLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYV-NTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRIC 162
Cdd:PRK05613 102 lNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVeNPDDPESWQAAVQPNTKAFFGETFANPQADVLDIPAVAEVA 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 163 DDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAARE--------------------------- 215
Cdd:PRK05613 182 HRNQVPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIDGGKfdwtverdgkpvfpyfvtpdpayhglk 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 216 --DLGDKlAFYQNA-------SGAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGRE 286
Cdd:PRK05613 262 yaDLGAP-AFGLKAragllrdTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEKVAKVNFAGLKDSPWYA 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 287 VhfQQASG---PGGMISFTLHDA-GKVPEVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSV 362
Cdd:PRK05613 341 T--KEKLGlkyTGSVLSFDIKGGkDEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEAGLARAGITQATVRLSV 418
|
410
....*....|....*..
gi 1897360700 363 GIENVHDLIDDLAQALA 379
Cdd:PRK05613 419 GIEDIDDIIADLEGGFA 435
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
7-379 |
2.37e-63 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 207.04 E-value: 2.37e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 7 SLLAQGGNGKDAGTGAVSFPIYQSATFRHPA----LGESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAIT- 81
Cdd:TIGR01324 1 TRLIHSGRQPRFSQGSVNPPLQRASTVLFDShaaqRRAKGELTYGRRGTLTHFALQDAMCELEGGAGCYLYPSGLAAVTn 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 82 AVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLREIRRI 161
Cdd:TIGR01324 81 SILAFVKAGDHVLMVDSAYEPTRYFCDIVLKRMGVDITYYDPLIGEDIATLIQPNTKVLFLEAPSSITFEIQDIPAIAKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 162 CDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGlAVAAREDLGDKLAFYQNASGAVLGPFDSWLLV 241
Cdd:TIGR01324 161 ARNPGIVIMIDNTWAAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIG-TVVANARTWDQLREHSYLMGQMVDADDAYTTL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 242 RGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDAGK--VPEVLSRIQLI 319
Cdd:TIGR01324 240 RGLRTLGVRLKQHQESSLAIAKWLSEQPEVARVLHPALPSCPGHEFWKRDFSGSSGLFSFVLQRLTQkqVHAFLDHLQLF 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 320 SFAESLGGVESLLtFPARQTHGDIPeDIRRrcGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:TIGR01324 320 GLGYSWGGYESLA-LCNQPELGHRP-NIKR--NLEGPLIRVHIGLENVDDLKADLKAGFE 375
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
7-378 |
1.63e-57 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 193.35 E-value: 1.63e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 7 SLLAQGGNGKDAGTGAVsFPIYQSATFRHPALG--------ESTGFDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLA 78
Cdd:PRK06702 9 TICVQGGYTPKNGEPRV-LPLYQSTTYKYDTSDdlaalfnlEAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASGQA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 79 AIT-AVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTS-DPEQVNAAVTSRTKAIFIETPTNPTMKITDLR 156
Cdd:PRK06702 88 AIMlAVLNICSSGDHLLCSSTVYGGTFNLFGVSLRKLGIDVTFFNPNlTADEIVALANDKTKLVYAESLGNPAMNVLNFK 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 157 EIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAV---------AAREDLGDKLAFYQNA 227
Cdd:PRK06702 168 EFSDAAKELEVPFIVDNTLATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdggnfdwtnGKYPELVEPDPSYHGV 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 228 S----------------------GAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLD---NH 282
Cdd:PRK06702 248 SyvqnfgaaayivkarvqllrdyGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDsneNY 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 283 PGREVHFQQasGPGGMISFTLH---DAGKvpEVLSRIQLISFAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLR 359
Cdd:PRK06702 328 SLAQKYLKK--GASGVLTFGIKgglEAAK--EFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIR 403
|
410
....*....|....*....
gi 1897360700 360 LSVGIENVHDLIDDLAQAL 378
Cdd:PRK06702 404 LSVGIEDVSDIIADLEAAL 422
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
1-379 |
5.23e-57 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 191.10 E-value: 5.23e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 1 MAMHIDSLLAQGGNGKDAGTGAVSFPIYQSATF--------RHPALGESTG-FDYSRSGNPTRQVLEELIAKLEGGRRGL 71
Cdd:PRK09028 1 MSEKKATKIVSAGRDKKWTKGVINPPVFRASTVvfdtvaemRHAAKNRANGeMFYGRRGTPTHFAFQAAIVELEGGAGTA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 72 AFSSGLAAIT-AVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTM 150
Cdd:PRK09028 81 LYPSGAAAISnALLSFLKAGDHLLMVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 151 KITDLREIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVaAREDLGDKLAFYQNASGA 230
Cdd:PRK09028 161 EVQDVPTLSRIAHEHDIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVMLGTAT-ANEKHWDQLREHSYLMGQ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 231 VLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLH--DAGK 308
Cdd:PRK09028 240 CTSPDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKqgDPKA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897360700 309 VPEVLSRIQLISFAESLGGVESLLTfparqthGDIPEDIRRRCGVTDC---LLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK09028 320 VTALVEGMQHFKMGFSWGGFESLIL-------GVFGINKLRTATNWDFskpLIRLHIGLEDVDDLIADLEAGFE 386
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
2-379 |
1.25e-56 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 190.02 E-value: 1.25e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 2 AMHIDSLLAQGGNGKDAGTGAVSFPIYQSAT--FRHPALGESTG--FDYSRSGNPTRQVLEELIAKLEGGRRGLAFSSGL 77
Cdd:PRK05967 10 KAGINTRLAHDGNDPGDYHGFVNPPVVHASTvlFPDAETMATRGqkYTYGTRGTPTTDALCKAIDALEGSAGTILVPSGL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 78 AAITA-VISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMKITDLR 156
Cdd:PRK05967 90 AAVTVpFLGFLSPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQDIP 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 157 EIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGlAVAAREDLGDKLAFYQNASGAVLGPFD 236
Cdd:PRK05967 170 AIAEAAHRHGAIVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLG-TVSANEKCWPQLLEAHGTLGLCAGPDD 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 237 SWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDAG-----KVPE 311
Cdd:PRK05967 249 TYQILRGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSGASGIFSFVLAAGPekgkaKAHA 328
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897360700 312 VLSRIQLISFAESLGGVESLltfparQTHGDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK05967 329 FLDALEIFGLGYSWGGYESL------ALHVKLGDRTVAKAPYAGPVIRLQIGLEDVPDLKADLERGFA 390
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
4-379 |
3.84e-54 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 183.37 E-value: 3.84e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 4 HIDSLLAQGGNGKDAGTGAVSfPIYQSAT---F------RHPALGESTG--FdYSRSGNPTRQVLEELIAKLEGGRRGLA 72
Cdd:PRK08114 5 KLDTQLVNAGRSKKYTQGSVN-SVIQRASslvFdsveakKHATRNRANGelF-YGRRGTLTHFSLQEAMCELEGGAGCAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 73 FSSGLAAIT-AVISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMK 151
Cdd:PRK08114 83 YPCGAAAVAnAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGSITME 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 152 ITDL----REIRRICDDggLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVA-ARedLGDKLAFYQN 226
Cdd:PRK08114 163 VHDVpaivAAVRSVNPD--AVIMIDNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIGTAVAnAR--CWEQLRENSY 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 227 ASGAVLGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLHDA 306
Cdd:PRK08114 239 LMGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKKK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 307 ---GKVPEVLSRIQLISFAESLGGVESLLTfpARQthgdiPED---IRRRCGV--TDCLLRLSVGIENVHDLIDDLAQAL 378
Cdd:PRK08114 319 ltdEQLANYLDNFSLFSMAYSWGGFESLIL--ANQ-----PEEiaaIRPAGEVdfTGTLIRLHIGLEDVDDLIADLAAGF 391
|
.
gi 1897360700 379 A 379
Cdd:PRK08114 392 A 392
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
1-379 |
8.47e-49 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 169.52 E-value: 8.47e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 1 MAMHIDSLLAQGGNGKDAGTGAVSFPIYQSATFRHPALGESTGFD--------YSRSGNPTRQVLEELIAKLEGGRRGLA 72
Cdd:PRK07050 6 PKRALQTRIVQPDDQIPPGFRSFVTPVARASTVVFPDLATMRALDwrqdvqwrYGLHATPTSLALAQRLAEIEGGRHALL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 73 FSSGLAAITAV-ISLFGPGDHLILCEDLYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMK 151
Cdd:PRK07050 86 QPSGLAAISLVyFGLVKAGDDVLIPDNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTME 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 152 ITDLREIRRICDDGGLLLIVDNTFISPYLQRPIECGADIVIHSGTKYLGGHNDVVAGLAVAAREDLGDKLAFYQNASGAV 231
Cdd:PRK07050 166 VPDVPAITAAARARGVVTAIDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADAELHAKLKLARMRLGIG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 232 LGPFDSWLLVRGMKTLGLRLDRAQENASAIARWLASHPAVDQVYYIGLDNHPGREVHFQQASGPGGMISFTLH---DAGK 308
Cdd:PRK07050 246 VSADDCSLVLRGLPSLQVRLAAHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLFSVVFDerySPAQ 325
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897360700 309 VPEVLSRIQLISFAESLGGVESlLTFPArqthgDIPEDIRRRCGVTDCLLRLSVGIENVHDLIDDLAQALA 379
Cdd:PRK07050 326 VDAFVEALELFAIGWSWGGACS-LAMPY-----DVASMRTAKWPHRGTLVRLYIGLEDEADLIADLEQALE 390
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
21-364 |
4.18e-48 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 168.02 E-value: 4.18e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 21 GAVSFPIYQSATF--RHP---------ALGESTGFD-YSRSGNPTRQVLEELIAKLEGGRRGLAFSSGLAAITAVI-SLF 87
Cdd:PLN02242 33 GGVNMSIEASATFtvMEPdtmrrmfsgELGPDRDFYiYSRHFNPTVLNLGRQMAALEGTEAAYCTASGMSAISSVLlQLC 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 88 GPGDHLILCEDLYGGTYRLLEQVF-RPWGLTADYVNTSDPEQVNAAVT-SRTKAIFIETPTNPTMKITDLREIRRICDDG 165
Cdd:PLN02242 113 SSGGHVVASNTLYGGTHALLAHFLpRKCNITTTFVDITDLEAVKKAVVpGKTKVLYFESISNPTLTVADIPELARIAHEK 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 166 GLLLIVDNTFiSPYLQRPIECGADIVIHSGTKYLGGHNDVVAGlAVAAREDLGDKLAFYQNASGAVLGP-------FDsw 238
Cdd:PLN02242 193 GVTVVVDNTF-APMVLSPARLGADVVVHSISKFISGGADIIAG-AVCGPAELVNSMMDLHHGALMLLGPtmnpkvaFE-- 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 239 lLVRGMKTLGLRL----DRAQENASAIARWLAshpavdQVYYIGLDNHPGREVHFQQAS---GPGGMISFTLHDAGKVPE 311
Cdd:PLN02242 269 -LSERLPHLSLRMkehcRRAMEYAKRMKELGL------KVIYPGLEDHPQHALLKSMANkgyGFGGLLCLDMDTEERANR 341
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897360700 312 VLSRIQLIS----FAESLGGVESLLTFPARQTHGDIPEDIRRRCGVTDCLLRLSVGI 364
Cdd:PLN02242 342 LMRYLQNSTqfgfMAVSLGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVGY 398
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
54-201 |
1.12e-13 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 68.56 E-value: 1.12e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 54 RQVLEELIAKLEGGR--RGLAFSSGLAAITAVI-SLFGPGDHLILCEDLYGGTYRL------LEQVFRPWGLTADYVNTS 124
Cdd:cd01494 2 LEELEEKLARLLQPGndKAVFVPSGTGANEAALlALLGPGDEVIVDANGHGSRYWVaaelagAKPVPVPVDDAGYGGLDV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 125 DPEqVNAAVTSRTKAIFIETPTNPTMKITDLREIRRICDDGGLLLIVDNTFISPY----LQRPIECGADIVIHSGTKYLG 200
Cdd:cd01494 82 AIL-EELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGAspapGVLIPEGGADVVTFSLHKNLG 160
|
.
gi 1897360700 201 G 201
Cdd:cd01494 161 G 161
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
57-269 |
3.03e-10 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 60.82 E-value: 3.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 57 LEELIAKLEGGRRGLA--------FSSGLAAITAVISLF-GPGDHLILCE---DLYGGTYRLLEQVFRPWGLTADYVNTS 124
Cdd:cd00609 41 LREAIAEWLGRRGGVDvppeeivvTNGAQEALSLLLRALlNPGDEVLVPDptyPGYEAAARLAGAEVVPVPLDEEGGFLL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 125 DPEQVNAAVTSRTKAIFIETPTNPT---MKITDLREIRRICDDGGLLLIVDNT---FISPYLQRPIECGAD-----IVIH 193
Cdd:cd00609 121 DLELLEAAKTPKTKLLYLNNPNNPTgavLSEEELEELAELAKKHGILIISDEAyaeLVYDGEPPPALALLDayervIVLR 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 194 SGTKYLGghndvVAGL----AVAAREDLGDKLAFYQNASGAVLGPFDSWLLVRGMKTLGLRLDRA----QENASAIARWL 265
Cdd:cd00609 201 SFSKTFG-----LPGLrigyLIAPPEELLERLKKLLPYTTSGPSTLSQAAAAAALDDGEEHLEELreryRRRRDALLEAL 275
|
....
gi 1897360700 266 ASHP 269
Cdd:cd00609 276 KELG 279
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
79-255 |
5.55e-09 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 57.06 E-value: 5.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 79 AITAVI-SLFGPGDHLILCE----------DLYGGTYRLL----EQVFRPwgltadyvntsDPEQVNAAVTSRTKAIFIE 143
Cdd:COG0436 102 ALALALlALLNPGDEVLVPDpgypsyraavRLAGGKPVPVpldeENGFLP-----------DPEALEAAITPRTKAIVLN 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 144 TPTNPT---MKITDLREIRRICDDGGLLLIVDNT----------FISPyLQRPiecGAD---IVIHSGTK---------- 197
Cdd:COG0436 171 SPNNPTgavYSREELEALAELAREHDLLVISDEIyeelvydgaeHVSI-LSLP---GLKdrtIVINSFSKsyamtgwrig 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 198 YLGGHNDVVAGLAvaaredlgdKLAFY---------QNASGAVLGPFDSW-------------LLVRGMKTLGLRLDRAQ 255
Cdd:COG0436 247 YAVGPPELIAALL---------KLQSNltscaptpaQYAAAAALEGPQDYveemraeyrrrrdLLVEGLNEIGLSVVKPE 317
|
|
| YnbB |
COG4100 |
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion ... |
41-223 |
5.63e-09 |
|
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 443276 Cd Length: 409 Bit Score: 57.42 E-value: 5.63e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 41 STGFDYSRSGnptRQVLEELIAKLEGGRRGL---AFSSGLAAITAVisLFG---PGDHLilcedLY--GGTYRLLEQV-- 110
Cdd:COG4100 49 TTGYGYDDIG---RDTLERVYADVFGAEDALvrpQIVSGTHAIALA--LFGvlrPGDEL-----LSitGKPYDTLEEVig 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 111 --------FRPWGLTADYV-----NTSDPEQVNAAVTSRTKAIFIETPT----NPTMKITDLRE----IRRICDDggLLL 169
Cdd:COG4100 119 irgegqgsLKEFGISYRQVpltedGKIDLEAIKKAINEKTKMVLIQRSRgyswRPSLTIEEIGEiikfVKSINPD--VIC 196
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897360700 170 IVDN---TFISPylQRPIECGADIVIHSGTKYLGGhndvvaGLA-----VAAREDLGDKLAF 223
Cdd:COG4100 197 FVDNcygEFVET--REPTEVGADLMAGSLIKNPGG------GLAptggyIAGRKDLVELAAY 250
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
75-175 |
3.13e-08 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 55.08 E-value: 3.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 75 SGLAAITAVISLFGPGDHLILCEDLYGGTyrllEQVFRPWGLTADYVNTSD-----PEQVNAAVTSRTKAIFIETPTNPT 149
Cdd:PRK05957 98 SNMAFMNAILAITDPGDEIILNTPYYFNH----EMAITMAGCQPILVPTDDnyqlqPEAIEQAITPKTRAIVTISPNNPT 173
|
90 100
....*....|....*....|....*....
gi 1897360700 150 MKI---TDLREIRRICDDGGLLLIVDNTF 175
Cdd:PRK05957 174 GVVypeALLRAVNQICAEHGIYHISDEAY 202
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
125-172 |
1.31e-07 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 52.82 E-value: 1.31e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1897360700 125 DPEQVNAAVTSRTKAIFIETPTNPT-MKIT--DLREIRRICDDGGLLLIVD 172
Cdd:PRK05764 153 TVEQLEAAITPKTKALILNSPSNPTgAVYSpeELEAIADVAVEHDIWVLSD 203
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
78-172 |
2.71e-07 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 51.96 E-value: 2.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 78 AAITA-VISLFGPGDHLILCE---DLYGGTYRLLEQVFRPWGLTADYVN-TSDPEQVNAAVTSRTKAIFIETPTNPTMKI 152
Cdd:PRK07777 96 EAIAAaVLGLVEPGDEVLLIEpyyDSYAAVIAMAGAHRVPVPLVPDGRGfALDLDALRAAVTPRTRALIVNSPHNPTGTV 175
|
90 100
....*....|....*....|...
gi 1897360700 153 ---TDLREIRRICDDGGLLLIVD 172
Cdd:PRK07777 176 ltaAELAAIAELAVEHDLLVITD 198
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
52-269 |
8.27e-07 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 50.36 E-value: 8.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 52 PTRQVLEELIAKLEGGRRGLAFSSGLAAITAVISLFG--PGDHLILCEDLYGGTyrllEQVFRPWGLTADYV----NTS- 124
Cdd:pfam01041 24 PYVREFERAFAAYLGVKHAIAVSSGTAALHLALRALGvgPGDEVITPSFTFVAT----ANAALRLGAKPVFVdidpDTYn 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 125 -DPEQVNAAVTSRTKAIFietPTNPTMKITDLREIRRICDDGGLLLIVD--NTFISPYLQRPIECGADIVIHS--GTKYL 199
Cdd:pfam01041 100 iDPEAIEAAITPRTKAII---PVHLYGQPADMDAIRAIAARHGLPVIEDaaHALGATYQGKKVGTLGDAATFSfhPTKNL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 200 ----GGhndvvaglAVAAR-EDLGDKLAFYQNASGAVLGPFDSWLLVRGMKT--------LGL----RLD----RAQENA 258
Cdd:pfam01041 177 ttgeGG--------AVVTNdPELAEKARVLRNHGMVRKADKRYWHEVLGYNYrmteiqaaIGLaqleRLDefiaRRREIA 248
|
250
....*....|.
gi 1897360700 259 SAIARWLASHP 269
Cdd:pfam01041 249 ALYQTLLADLP 259
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
78-175 |
8.54e-07 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 50.34 E-value: 8.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 78 AAITAVISLFGPGDHLILCedlyggtyrlleqvfRPW-----------GLTADYVNTS-------DPEQVNAAVTSRTKA 139
Cdd:PRK07550 102 AFWAAMVTLAGAGDEVILP---------------LPWyfnhkmwldmlGIRPVYLPCDegpgllpDPAAAEALITPRTRA 166
|
90 100 110
....*....|....*....|....*....|....*....
gi 1897360700 140 IFIETPTNPTMKITD---LREIRRICDDGGLLLIVDNTF 175
Cdd:PRK07550 167 IALVTPNNPTGVVYPpelLHELYDLARRHGIALILDETY 205
|
|
| PRK15407 |
PRK15407 |
lipopolysaccharide biosynthesis protein RfbH; Provisional |
125-173 |
1.11e-06 |
|
lipopolysaccharide biosynthesis protein RfbH; Provisional
Pssm-ID: 237960 Cd Length: 438 Bit Score: 50.27 E-value: 1.11e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1897360700 125 DPEQVNAAVTSRTKAIFI-ETPTNPtmkiTDLREIRRICDDGGLLLIVDN 173
Cdd:PRK15407 148 DASLLEAAVSPKTKAIMIaHTLGNP----FDLAAVKAFCDKHNLWLIEDN 193
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
78-176 |
1.45e-06 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 49.74 E-value: 1.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 78 AAITAVISLF-GPGDHLILCEdlygGTYRLLEQVFRPWGLTADYVNTS-----DPEQVNAAVTSRTKAIFIETPTNPTMK 151
Cdd:COG0079 76 ELIQLLARAFlGPGDEVLVPE----PTFSEYPIAARAAGAEVVEVPLDedfslDLDALLAAITERTDLVFLCNPNNPTGT 151
|
90 100
....*....|....*....|....*..
gi 1897360700 152 ITDLREIRRICD--DGGLLLIVDNTFI 176
Cdd:COG0079 152 LLPREELEALLEalPADGLVVVDEAYA 178
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
79-175 |
5.55e-06 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 47.94 E-value: 5.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 79 AITAVI-SLFGPGDHLILCE---DLYGGTYRLLEQVFRpwGLTADYVNTSDP-EQVNAAVTSRTKAIFIETPTNPTMKI- 152
Cdd:PLN00175 127 AIAATIlGLINPGDEVILFApfyDSYEATLSMAGAKIK--TVTLRPPDFAVPeDELKAAFTSKTRAILINTPHNPTGKMf 204
|
90 100
....*....|....*....|....*
gi 1897360700 153 --TDLREIRRICDDGGLLLIVDNTF 175
Cdd:PLN00175 205 trEELELIASLCKENDVLAFTDEVY 229
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
57-172 |
5.65e-06 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 47.69 E-value: 5.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 57 LEELIAKLEGGRRGLA--------FSSG-LAAITAVISLFGPGDHLILCEDLYGGTYrllEQVFRPWGLTADYVNTSDP- 126
Cdd:pfam00155 44 LREALAKFLGRSPVLKldreaavvFGSGaGANIEALIFLLANPGDAILVPAPTYASY---IRIARLAGGEVVRYPLYDSn 120
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1897360700 127 ------EQVNAAVTSRTKAIFIETPTNPT---MKITDLREIRRICDDGGLLLIVD 172
Cdd:pfam00155 121 dfhldfDALEAALKEKPKVVLHTSPHNPTgtvATLEELEKLLDLAKEHNILLLVD 175
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
82-172 |
7.96e-06 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 47.42 E-value: 7.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 82 AVISLFGPGDHLILCED---LYGGTYRLLEQVFRPWGLTADYVNTSDPEQVNAAVTSRTKAIFIETPTNPT---MKITDL 155
Cdd:PRK07682 97 AMRAIINPGDEVLIVEPsfvSYAPLVTLAGGVPVPVATTLENEFKVQPAQIEAAITAKTKAILLCSPNNPTgavLNKSEL 176
|
90
....*....|....*..
gi 1897360700 156 REIRRICDDGGLLLIVD 172
Cdd:PRK07682 177 EEIAVIVEKHDLIVLSD 193
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
52-172 |
2.13e-05 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 46.09 E-value: 2.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 52 PTRQVLEELIAKLEGGR----RGLAFSSGLAAIT-AVISLFGPGDHLILCEDLYGGtyrLLEQV----FRPWGLTADYVN 122
Cdd:PRK06108 65 ELREALARYVSRLHGVAtppeRIAVTSSGVQALMlAAQALVGPGDEVVAVTPLWPN---LVAAPkilgARVVCVPLDFGG 141
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1897360700 123 ---TSDPEQVNAAVTSRTKAIFIETPTNPT---MKITDLREIRRICDDGGLLLIVD 172
Cdd:PRK06108 142 ggwTLDLDRLLAAITPRTRALFINSPNNPTgwtASRDDLRAILAHCRRHGLWIVAD 197
|
|
| PRK00451 |
PRK00451 |
aminomethyl-transferring glycine dehydrogenase subunit GcvPA; |
123-192 |
2.53e-05 |
|
aminomethyl-transferring glycine dehydrogenase subunit GcvPA;
Pssm-ID: 234769 [Multi-domain] Cd Length: 447 Bit Score: 45.90 E-value: 2.53e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897360700 123 TSDPEQVNAAVTSRTKAIFIETPtNPTMKITDLREIRRICDDGGLLLIVdntFISP----YLQRPIECGADIVI 192
Cdd:PRK00451 191 VTDLEALEAAVDDDTAAVVVQYP-NFFGVIEDLEEIAEIAHAGGALFIV---GVDPvslgLLKPPGEYGADIVV 260
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
57-173 |
3.96e-05 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 45.06 E-value: 3.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 57 LEELIAKLEGGRRGLAFSSGLAAI-TAVISL-FGPGDHLIL----------CEDLYGGTyrlleQVF---RPWGLTADyv 121
Cdd:COG0399 35 FEEEFAAYLGVKHAVAVSSGTAALhLALRALgIGPGDEVITpaftfvatanAILYVGAT-----PVFvdiDPDTYNID-- 107
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1897360700 122 ntsdPEQVNAAVTSRTKAIFietPT----NPtmkiTDLREIRRICDDGGLLLIVDN 173
Cdd:COG0399 108 ----PEALEAAITPRTKAII---PVhlygQP----ADMDAIMAIAKKHGLKVIEDA 152
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
54-175 |
7.97e-05 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 44.39 E-value: 7.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 54 RQVLEELIAKLEGGRRGLA--------FSSGL-AAITAvisLFGPGDHLILCE---DLYGGTYRLLEQVFRPWGLTADYV 121
Cdd:PRK12414 72 REALAEKTERLYGARYDPAsevtviasASEGLyAAISA---LVHPGDEVIYFEpsfDSYAPIVRLQGATPVAIKLSPEDF 148
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897360700 122 NTsDPEQVNAAVTSRTKAIFIETPTNPTMKI---TDLREIRRICDDGGLLLIVDNTF 175
Cdd:PRK12414 149 RV-NWDEVAAAITPRTRMIIVNTPHNPSATVfsaADLARLAQLTRNTDIVILSDEVY 204
|
|
| argD |
PRK01278 |
acetylornithine transaminase protein; Provisional |
119-172 |
8.81e-05 |
|
acetylornithine transaminase protein; Provisional
Pssm-ID: 179270 [Multi-domain] Cd Length: 389 Bit Score: 44.06 E-value: 8.81e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897360700 119 DYVNTSDPEQVNAAVTSRTKAIFIEtptnP--------TMKITDLREIRRICDDGGLLLIVD 172
Cdd:PRK01278 158 DQVPFGDIEALKAAITPNTAAILIE----PiqgeggirPAPDEFLKGLRQLCDENGLLLIFD 215
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
77-172 |
1.19e-04 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 43.75 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 77 LAAITAVIslfGPGDHLIL---CEDLYGGTYRLLEQVFRPWGLTA-DYvnTSDPEQVNAAVTSRTKAIFIETPTNPTMKI 152
Cdd:PRK09082 105 FAAILALV---RPGDEVIVfdpSYDSYAPAIELAGGRAVRVALQPpDF--RVDWQRFAAAISPRTRLIILNTPHNPSGTV 179
|
90 100
....*....|....*....|...
gi 1897360700 153 ---TDLREIRRICDDGGLLLIVD 172
Cdd:PRK09082 180 wsaADMRALWQLIAGTDIYVLSD 202
|
|
| KBL_like |
cd06454 |
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate ... |
49-224 |
1.31e-04 |
|
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS), 8-amino-7-oxononanoate synthase (AONS), and 2-amino-3-ketobutyrate CoA ligase (KBL). SPT is responsible for the condensation of L-serine with palmitoyl-CoA to produce 3-ketodihydrospingosine, the reaction of the first step in sphingolipid biosynthesis. ALAS is involved in heme biosynthesis; it catalyzes the synthesis of 5-aminolevulinic acid from glycine and succinyl-coenzyme A. AONS catalyses the decarboxylative condensation of l-alanine and pimeloyl-CoA in the first committed step of biotin biosynthesis. KBL catalyzes the second reaction step of the metabolic degradation pathway for threonine converting 2-amino-3-ketobutyrate, to glycine and acetyl-CoA. The members of this CD are widely found in all three forms of life.
Pssm-ID: 99747 [Multi-domain] Cd Length: 349 Bit Score: 43.70 E-value: 1.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 49 SGN-PTRQVLEELIAKLEGGRRGLAFSSGLAAITAVIS-LFGPGDHLILCED----------LYGGTYRlleqVFRpwgl 116
Cdd:cd06454 42 SGTsDLHEELEEELAEFHGKEAALVFSSGYAANDGVLStLAGKGDLIISDSLnhasiidgirLSGAKKR----IFK---- 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 117 tadYVNTSDPEQVNAAVTSRTKAIFIETPTNPTMK--ITDLREIRRICDDGGLLLIVDNT----FISP----YLQRPIEC 186
Cdd:cd06454 114 ---HNDMEDLEKLLREARRPYGKKLIVTEGVYSMDgdIAPLPELVDLAKKYGAILFVDEAhsvgVYGPhgrgVEEFGGLT 190
|
170 180 190
....*....|....*....|....*....|....*....
gi 1897360700 187 GA-DIVIHSGTKYLGghndvVAGLAVAAREDLGDKLAFY 224
Cdd:cd06454 191 DDvDIIMGTLGKAFG-----AVGGYIAGSKELIDYLRSY 224
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
57-175 |
1.65e-04 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 43.26 E-value: 1.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 57 LEELIAKLEGGRRGLAFSSGLAAITAVIS-----LFG----PGDHLILCE----------DLYGGT---YRLLEQvfRPW 114
Cdd:PRK08363 75 LREAIVKREKRKNGVDITPDDVRVTAAVTealqlIFGalldPGDEILIPGpsyppytglvKFYGGVpveYRTIEE--EGW 152
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897360700 115 gltadyvnTSDPEQVNAAVTSRTKAIFIETPTNPTMKITD---LREIRRICDDGGLLLIVDNTF 175
Cdd:PRK08363 153 --------QPDIDDIRKKITEKTKAIAVINPNNPTGALYEkktLKEILDIAGEHDLPVISDEIY 208
|
|
| SelA |
COG1921 |
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis]; |
57-221 |
1.96e-04 |
|
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441524 Cd Length: 399 Bit Score: 43.19 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 57 LEELIAKLEGGRRGLAFSSGLAAITAVISLFGPGDHLI-----LCEdlYGGTYRLlEQVFRPWGLT---ADYVNTSDPEQ 128
Cdd:COG1921 70 VEELLCELTGAEAALVVNNNAAAVLLALAALAAGKEVIvsrgeLVE--IGGSFRI-PDVMALSGAKlveVGTTNRTHLRD 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 129 VNAAVTSRTKAIF--------IETPTnptmKITDLREIRRICDDGGLLLIVD---------NTFISPY---LQRPIECGA 188
Cdd:COG1921 147 YEAAITENTAALLkvhtsnyrIVGFT----EEVSLAELAELAHEHGLPVIVDlgsgslvdlSKYGLPHeptVQEYLAAGA 222
|
170 180 190
....*....|....*....|....*....|...
gi 1897360700 189 DIVIHSGTKYLGGhndVVAGLaVAAREDLGDKL 221
Cdd:COG1921 223 DLVTFSGDKLLGG---PQAGI-IVGKKELIERI 251
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
50-173 |
2.42e-04 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 42.53 E-value: 2.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 50 GNPTRQvLEELIAKLEGGRRGLAFSSGLAAI-TAVISLF-GPGDHLILCEDLYGGT-----YRLLEQVFrpwgltADYVN 122
Cdd:cd00616 17 GPKVRE-FEKAFAEYLGVKYAVAVSSGTAALhLALRALGiGPGDEVIVPSFTFVATanailLLGATPVF------VDIDP 89
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1897360700 123 TS---DPEQVNAAVTSRTKAIFietPTNPTMKITDLREIRRICDDGGLLLIVDN 173
Cdd:cd00616 90 DTyniDPELIEAAITPRTKAII---PVHLYGNPADMDAIMAIAKRHGLPVIEDA 140
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
125-175 |
4.72e-04 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 42.01 E-value: 4.72e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1897360700 125 DPEQVNAAVTSRTKAIFIETPTNPT---MKITDLREIRRICDDGGLLLIVDNTF 175
Cdd:PRK06348 151 NVKKLEALITSKTKAIILNSPNNPTgavFSKETLEEIAKIAIEYDLFIISDEVY 204
|
|
| PRK02627 |
PRK02627 |
acetylornithine aminotransferase; Provisional |
119-172 |
5.84e-04 |
|
acetylornithine aminotransferase; Provisional
Pssm-ID: 235056 [Multi-domain] Cd Length: 396 Bit Score: 41.66 E-value: 5.84e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 119 DYVNTSDPEQVNAAVTSRTKAIFIEtP------TNPtMKITDLREIRRICDDGGLLLIVD 172
Cdd:PRK02627 165 IYVPFNDIEALKAAITDKTAAVMLE-PiqgeggVNP-ADKEYLQALRELCDENGILLILD 222
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
78-172 |
6.10e-04 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 41.38 E-value: 6.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 78 AAITAVISLFGPGDHLILCEDLYG---GTYRLLEQVFRPWGLTADY-VNTSDPEQVNAAVTSRTKAIFIETPTNPTMKI- 152
Cdd:PRK07568 100 AILFAMMAICDPGDEILVPEPFYAnynGFATSAGVKIVPVTTKIEEgFHLPSKEEIEKLITPKTKAILISNPGNPTGVVy 179
|
90 100
....*....|....*....|..
gi 1897360700 153 --TDLREIRRICDDGGLLLIVD 172
Cdd:PRK07568 180 tkEELEMLAEIAKKHDLFLISD 201
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
77-158 |
7.71e-04 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 41.11 E-value: 7.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 77 LAAitAVISLFGPGDHLILCEDLY----------GGTYRLLEqvFRP--WGLtadyvntsDPEQVNAAVTSRTKAIFIET 144
Cdd:PRK08912 100 LAA--ALLALVEPGDEVVLFQPLYdaylplirraGGVPRLVR--LEPphWRL--------PRAALAAAFSPRTKAVLLNN 167
|
90
....*....|....
gi 1897360700 145 PTNPTMKITDLREI 158
Cdd:PRK08912 168 PLNPAGKVFPREEL 181
|
|
| Orn_deC_like |
cd00615 |
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
58-201 |
1.53e-03 |
|
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.
Pssm-ID: 99739 [Multi-domain] Cd Length: 294 Bit Score: 39.92 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 58 EELIAKLEGGRRglAF-----SSGlaAITAVI-SLFGPGDHLILCEDLYGGTYRLLeqVFRpwGLTADYVNTS------- 124
Cdd:cd00615 65 QELAARAFGAKH--TFflvngTSS--SNKAVIlAVCGPGDKILIDRNCHKSVINGL--VLS--GAVPVYLKPErnpyygi 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 125 ----DPEQVNAAVTSRT--KAIFIetpTNPTMK--ITDLREIRRICDDGGLLLIVDNT------FISPYLQRPIECGADI 190
Cdd:cd00615 137 aggiPPETFKKALIEHPdaKAAVI---TNPTYYgiCYNLRKIVEEAHHRGLPVLVDEAhgahfrFHPILPSSAAMAGADI 213
|
170
....*....|.
gi 1897360700 191 VIHSGTKYLGG 201
Cdd:cd00615 214 VVQSTHKTLPA 224
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
87-201 |
1.54e-03 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 40.14 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 87 FGPGDHLILCEdlyggtyrlLEQ--VFRPW-------GLTADYV-----NTSDPEQVNAAVTSRTKAIFIETPTNPTMKI 152
Cdd:cd06453 85 NKPGDEIVTSV---------MEHhsNIVPWqqlaertGAKLKVVpvdddGQLDLEALEKLLTERTKLVAVTHVSNVLGTI 155
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1897360700 153 TDLREIRRICDDGGLLLIVDNTFISPYLqrPI---ECGADIVIHSGTKYLGG 201
Cdd:cd06453 156 NPVKEIGEIAHEAGVPVLVDGAQSAGHM--PVdvqDLGCDFLAFSGHKMLGP 205
|
|
| PRK03317 |
PRK03317 |
histidinol-phosphate aminotransferase; Provisional |
117-172 |
2.33e-03 |
|
histidinol-phosphate aminotransferase; Provisional
Pssm-ID: 235115 Cd Length: 368 Bit Score: 39.85 E-value: 2.33e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897360700 117 TADYvnTSDPEQVNAAVTSRTKAI-FIETPTNPTMKITDLREIRRICDDGGLLLIVD 172
Cdd:PRK03317 142 AADF--TLDVDAAVAAIAEHRPDVvFLTSPNNPTGTALPLDDVEAILDAAPGIVVVD 196
|
|
| BioF |
COG0156 |
7-keto-8-aminopelargonate synthetase or related enzyme [Coenzyme transport and metabolism]; ... |
57-95 |
2.56e-03 |
|
7-keto-8-aminopelargonate synthetase or related enzyme [Coenzyme transport and metabolism]; 7-keto-8-aminopelargonate synthetase or related enzyme is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 439926 [Multi-domain] Cd Length: 385 Bit Score: 39.65 E-value: 2.56e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1897360700 57 LEELIAKLEGGRRGLAFSSGLAAITAVIS-LFGPGDHLIL 95
Cdd:COG0156 87 LEEELAEFLGKEAALLFSSGYAANLGVISaLAGRGDLIFS 126
|
|
| ArgD |
COG4992 |
Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase [Amino acid transport and ... |
111-172 |
7.04e-03 |
|
Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase [Amino acid transport and metabolism]; Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase is part of the Pathway/BioSystem: Arginine biosynthesis
Pssm-ID: 444016 [Multi-domain] Cd Length: 396 Bit Score: 38.10 E-value: 7.04e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1897360700 111 FRPwgLTAD--YVNTSDPEQVNAAVTSRTKAIFIET---------PTNptmkiTDLREIRRICDDGGLLLIVD 172
Cdd:COG4992 156 FGP--LLPGfvFVPFNDLEALEAAIDDDTAAVIVEPiqgeggvipPPP-----GYLKGLRELCDEHGALLILD 221
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
78-163 |
8.00e-03 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 37.99 E-value: 8.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897360700 78 AAITAVISLFGPGDHLIlceDLYGgTYRLLEQVFRPWGLTADYVNTS-------DPEQVNAAVTSRTKAIFIETPTNPTM 150
Cdd:PRK07324 92 ANFLVLYALVEPGDHVI---SVYP-TYQQLYDIPESLGAEVDYWQLKeengwlpDLDELRRLVRPNTKLICINNANNPTG 167
|
90
....*....|....*....
gi 1897360700 151 KITD------LREIRRICD 163
Cdd:PRK07324 168 ALMDrayleeIVEIARSVD 186
|
|
| |
