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Conserved domains on  [gi|1896070013|gb|QNJ47162|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Tropidacris collaris]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 1.52e-90

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 274.01  E-value: 1.52e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   1 MKNNSTKLLFLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  81 NTPTGWEeqlIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILSYCIQMSMFTFtIIILSIII 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIII-IIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 161 GAMGGLNQTSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIYSASNMKTEIKFMM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 241 FLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISFSALIMSYTENSWLINKKNQTTTFILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*....
gi 1896070013 321 MTVMISTLGLISTSILISI 339
Cdd:MTH00160  317 FLSFISLFGLILSSLLFLL 335
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 1.52e-90

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 274.01  E-value: 1.52e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   1 MKNNSTKLLFLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  81 NTPTGWEeqlIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILSYCIQMSMFTFtIIILSIII 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIII-IIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 161 GAMGGLNQTSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIYSASNMKTEIKFMM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 241 FLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISFSALIMSYTENSWLINKKNQTTTFILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*....
gi 1896070013 321 MTVMISTLGLISTSILISI 339
Cdd:MTH00160  317 FLSFISLFGLILSSLLFLL 335
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 1.06e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 93.15  E-value: 1.06e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  24 SNSWFGVWMGLEINLLSFIPLM-VNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQMNTPT--------------GWEE 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTlsfdelskaltgglNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  89 QLIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLIL-MTWQKIAPMMIL-------SYCIQMSMFTFTIIILSIII 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 161 GAMGGLNQTSLRQILAYSSISHLGWMISSL----IISENVWELYFIIYSLLSLVMVL-----IFKQMNLFFLNQIYSASN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1896070013 232 MKTEIKFMMFLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 15-337 7.01e-15

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 74.98  E-value: 7.01e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  15 VVGTILSISSNSWFGVWMGLEINLLSFIPLM-VNNKNMMVNESSIKYFIVQAMASTMLLFSILLI----------QMNTP 83
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslnfeDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  84 TGWEEQLIP-----TMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIA---PMMILSYCIQMSM------F 149
Cdd:TIGR01770 192 LSNGMLNISllllgIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFGFseawqiF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 150 TFTIIILSIIIGAMGGLNQTSLRQILAYSSISHLGW-MISSLIISENVWE---LYFIIYSLLSLVMVLIFKQMNLFFLNQ 225
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEGIKavlFYIFIYALMSLGAFGVLSLLRSYKDEW 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 226 IYSASNMKTEIK------FMMFLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRIsfsALIM 299
Cdd:TIGR01770 352 IEYISDFAGLFKtnpilaILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKVM 428

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1896070013 300 SYTENS--WLINKKNQTTTFILPMTVMISTLGLISTSILI 337
Cdd:TIGR01770 429 YFDKPErrIPSNPQSKAQSLLLSISALFILFLGLFPSLIL 468
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 2.09e-13

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 70.53  E-value: 2.09e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   8 LLFLSTLvvGTILSISSNSWFGVWMGLEinLLSfIPLMV----NNKNMMVNESSIKYFIVQAMASTMLLFSILL------ 77
Cdd:COG1007   107 LLLFATL--GMMLMASANDLLTLFLGLE--LLS-LSLYVlvafRRDDRRSSEAALKYFLLGALSSGFLLYGISLlygatg 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  78 ------IQMNTPTGWEEQLIPTM---MISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILsycIQMSM 148
Cdd:COG1007   182 slnlagIAAALAAGGANSPLLLLglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAAL---LRLLV 258

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 149 FTFTIIILSIII------------GAMGGLNQTSLRQILAYSSISHLGWMISSLII-SENVWE---LYFIIYSLlslvmv 212
Cdd:COG1007   259 EAFPGLAADWQLllavlavlsmtvGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAgTPLGVSaalFYLLAYLF------ 332

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 213 lifkqMNL---FFLNQIYSASNMKTEIK-------------FMMFLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMA 276
Cdd:COG1007   333 -----MNLgafAVILLLSRKGGEAEEIEdlaglarrspllaLAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAV 407

                         330
                  ....*....|....*.
gi 1896070013 277 FMIVLTTITLYYYMRI 292
Cdd:COG1007   408 IAVLNSVISAYYYLRV 423
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-339 1.52e-90

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 274.01  E-value: 1.52e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   1 MKNNSTKLLFLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQM 80
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  81 NTPTGWEeqlIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILSYCIQMSMFTFtIIILSIII 160
Cdd:MTH00160   81 NLMLFNN---ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIII-IIILSAII 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 161 GAMGGLNQTSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIYSASNMKTEIKFMM 240
Cdd:MTH00160  157 GAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 241 FLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISFSALIMSYTENSWLINKKNQTTTFILP 320
Cdd:MTH00160  237 FLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILN 316

                         330
                  ....*....|....*....
gi 1896070013 321 MTVMISTLGLISTSILISI 339
Cdd:MTH00160  317 FLSFISLFGLILSSLLFLL 335
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 8-340 1.56e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 181.97  E-value: 1.56e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   8 LLFLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQMNTPTGWE 87
Cdd:MTH00105    7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQWTI 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  88 EQL---IPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMIL---SYCIQMSMFTfTIIILSIIIG 161
Cdd:MTH00105   87 TKLtnpTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILyqiSPSINPNLLL-TLAILSILIG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 162 AMGGLNQTSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIYSASNMKTEIKFMMF 241
Cdd:MTH00105  166 GWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLIL 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 242 LSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISFS-ALIMSYTENSWLIN--KKNQTTTFI 318
Cdd:MTH00105  246 LTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYStSLTMFPSTNNMKMKwqFENTKPMTL 325

                         330       340
                  ....*....|....*....|..
gi 1896070013 319 LPMTVMISTLGLISTSILISIY 340
Cdd:MTH00105  326 LPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 10-340 8.27e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 180.12  E-value: 8.27e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  10 FLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILL----------IQ 79
Cdd:MTH00070    9 LLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTInawftgewtiMN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  80 MNTPtgweeqlIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILsycIQMS-----MFTFTII 154
Cdd:MTH00070   89 MQTP-------LPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALL---IQIShllnsNLLIIMG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 155 ILSIIIGAMGGLNQTSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIySASNMKT 234
Cdd:MTH00070  159 LLSTLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKL-SSSWSKN 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 235 EIKFMMFLSLLSLGGLPPFL-GFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISFSALIMSY--TENSWLINKK 311
Cdd:MTH00070  238 PTLTSMMMLTLLSLGGLPPTtGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSpnTSNSKLYWRF 317

                         330       340
                  ....*....|....*....|....*....
gi 1896070013 312 NQTTTFILPMTVMISTLGLISTSILISIY 340
Cdd:MTH00070  318 KNKTNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 6-328 9.15e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 180.02  E-value: 9.15e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   6 TKLLFLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQMNTPTG 85
Cdd:MTH00112    5 AKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  86 WEEQL---IPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMIL---SYCIQMSMFTfTIIILSII 159
Cdd:MTH00112   85 DITQLtnpTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLlmtSNSLNPTLLL-TLAILSTL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 160 IGAMGGLNQTSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIYSASNMKTEIKFM 239
Cdd:MTH00112  164 IGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTT 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 240 MFLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISFSALI-----MSYTENSWLINKKNQT 314
Cdd:MTH00112  244 LMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTItlppnTTNMMMKWRTKPKKNT 323

                         330       340
                  ....*....|....*....|..
gi 1896070013 315 --------TTFILPMTVMISTL 328
Cdd:MTH00112  324 ltatlttlSTLLLPLSPMILTI 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 3-340 1.22e-53

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 179.74  E-value: 1.22e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   3 NNSTKLLFLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQMNT 82
Cdd:MTH00041    2 NRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  83 PT---GWEEQLIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILSYCIQMSMFTF--TIIILS 157
Cdd:MTH00041   82 GSwsiNGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNIliLCGILS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 158 IIIGAMGGLNQTSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIYSASNMKTEIK 237
Cdd:MTH00041  162 VLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISA 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 238 FMMFLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISFSALIMSYTENS-----WLINKKN 312
Cdd:MTH00041  242 FLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSislfsWRNSGNI 321

                         330       340
                  ....*....|....*....|....*...
gi 1896070013 313 QTTTFILPMTVMISTLGLISTSILISIY 340
Cdd:MTH00041  322 TVYGVILSILSSISILGLLLIPLFLSFL 349
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-328 1.13e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 171.01  E-value: 1.13e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   9 LFLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQMNTPTgwee 88
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYL---- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  89 QLIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILSYCIQMSMFTFTIIILSIIIGAMGGLNQ 168
Cdd:MTH00197   78 SLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQ 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 169 TSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIYSASNMKTEIKFMMFLSLLSLG 248
Cdd:MTH00197  158 SNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLG 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 249 GLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISFSALIMSYTENSWLINKKNQTTTFILPMTVMISTL 328
Cdd:MTH00197  238 GLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFILLMMMLPLL 317
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 6-339 2.84e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 168.22  E-value: 2.84e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   6 TKLLFLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQMNTPTG 85
Cdd:MTH00200    5 ILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  86 WEEQL---IPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILS--YCIQMSMFTFTIIILSIII 160
Cdd:MTH00200   85 GISEMlgpLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 161 GAMGGLNQTSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIYSASNMKTEIKFMM 240
Cdd:MTH00200  165 GGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 241 FLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISF-SALIMSYTENSWLIN-KKNQTTTFI 318
Cdd:MTH00200  245 GLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYlTLLTLSPNQINMMSSwRTKSNSNLL 324

                         330       340
                  ....*....|....*....|.
gi 1896070013 319 LPMTVMISTLGLISTSILISI 339
Cdd:MTH00200  325 VGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 7-321 1.10e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 166.21  E-value: 1.10e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   7 KLLFLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQMNTPTGW 86
Cdd:MTH00144    6 NLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  87 EeqlipTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILSYCI---QMSMFTFTIIILSIIIGAM 163
Cdd:MTH00144   86 S-----MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLdlyWLAYLLCVISVLSALVGSI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 164 GGLNQTSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIYSASNMKTEIKFMMFlS 243
Cdd:MTH00144  161 GGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIIS-L 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1896070013 244 LLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISFSALIMSYTENSWLINKKNQTTTFILPM 321
Cdd:MTH00144  240 LLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSIISLNL 317
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 9-330 1.74e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 160.74  E-value: 1.74e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   9 LFLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSIL----------LI 78
Cdd:MTH00135    8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnawltgqwdIQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  79 QMNTPtgweeqlIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILsycIQMSMFTFTIIILS- 157
Cdd:MTH00135   88 QMSHP-------LPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALI---LQIAPTNPTLLITLg 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 158 ---IIIGAMGGLNQTSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIySASNMKT 234
Cdd:MTH00135  158 ltsTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTL-ATSWTKA 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 235 EIKFMMFLSLLSLGGLPPFL-GFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISFS-ALIMSYTENSWLINKKN 312
Cdd:MTH00135  237 PALTALTPLILLSLGGLPPLtGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAmTLTISPNTLNGTTPWRL 316

                         330
                  ....*....|....*....
gi 1896070013 313 QTTTFILPM-TVMISTLGL 330
Cdd:MTH00135  317 PSTQLTLPLaISTTATLML 335
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-321 7.24e-45

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 156.09  E-value: 7.24e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   6 TKLLFLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSIlliQMNTPTG 85
Cdd:MTH00011    7 TMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM---TMMWSFP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  86 WEEQLIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILSYCIQMSMFTFTIII--LSIIIGAM 163
Cdd:MTH00011   84 SLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMaaMSALAGGL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 164 GGLNQTSLRQILAYSSISHLGWMISSLIISENVWELYFIIYSLLSLVMVLIFKQMNLFFLNQIYSASNMKTEIKFMMFLS 243
Cdd:MTH00011  164 GGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIM 243

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1896070013 244 LLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRISFSALIMSYTENSWLINKKNQTTTFILPM 321
Cdd:MTH00011  244 LLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSPTFSSLKSAPYEPKTKILISM 321
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 24-282 1.06e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 93.15  E-value: 1.06e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  24 SNSWFGVWMGLEINLLSFIPLM-VNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQMNTPT--------------GWEE 88
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTlsfdelskaltgglNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  89 QLIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLIL-MTWQKIAPMMIL-------SYCIQMSMFTFTIIILSIII 160
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 161 GAMGGLNQTSLRQILAYSSISHLGWMISSL----IISENVWELYFIIYSLLSLVMVL-----IFKQMNLFFLNQIYSASN 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1896070013 232 MKTEIKFMMFLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLT 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 14-292 8.26e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 83.16  E-value: 8.26e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  14 LVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVN-ESSIKYFIVQAMASTMLLF------------SILLIQM 80
Cdd:MTH00196    2 VALGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGYSaEAGLKYFVLGALSSGLFLFgcallcgttgglHLSYINL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  81 NTPTGWE----EQLIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILSYCIQMSMFTFTIIIL 156
Cdd:MTH00196   82 VLNSGQSfssvSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLF 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 157 SIIIGAMGGLNQTSLRQILAYSSISHLGWMISSL----IISENVWELYFIIYSLLSLVMVLIFKQMNlFFLNQIYSASNM 232
Cdd:MTH00196  162 SLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYIIMSICVFSIILALN-VYKNLIIEFSGL 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1896070013 233 KTEIKFMMFLSLLSLGGLP---PFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRI 292
Cdd:MTH00196  241 SRRLPILAITLALTFLSIAgipPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
15-292 1.52e-15

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 77.17  E-value: 1.52e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  15 VVGTILSISSNSWFGVWMGLEI-NLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLI--------------- 78
Cdd:PRK05777  113 LLGMMVMVSANDLLTLFLGLELlSLPLYALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLygatgslsfagiaka 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  79 ---QMNTPTGWeeqLIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMIL---------SYCIQM 146
Cdd:PRK05777  193 ladGSGNSLLL---LFGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvafgGLSEDW 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 147 SMFTFTIIILSIIIGAMGGLNQTSLRQILAYSSISHLGWMISSLIIS-----ENVWeLYFIIYSLLSL-----VMVLIFK 216
Cdd:PRK05777  270 QQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGtaegySAVL-FYLLAYLFMTLgafgvISLLRRK 348

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1896070013 217 QM---NLFFLNQIYSASNMKTeikFMMFLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRI 292
Cdd:PRK05777  349 GGeaeSISDFAGLSKRSPLLA---AVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 14-292 2.81e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 76.21  E-value: 2.81e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  14 LVVGTILSISSNSWFGVWMGLEINLLS-FIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILL---------IQMNTP 83
Cdd:MTH00199  106 VALGSLLLVSSINWLSIYLAIELQTLTlFILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALlygltgetsIQGINS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  84 TGWEEqlIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILSYCIQMSMFTFTIIILSIIIGAM 163
Cdd:MTH00199  186 ILTGD--VGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGAI 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 164 GGLNQTSLRQILAYSSISHLGWMISSLIISEN----VWELYFIIYSLLSLVMVLIFKQMNLF--FLNQIYSASNMKTEIK 237
Cdd:MTH00199  264 GALNQTKIKRLLAYSGIGHMGFILFGVAIGSFesiqASLIYMIIYVIMSICSFSIILSLKLTkgLIVEVSGLSRKNPVIA 343

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1896070013 238 FMMFLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRI 292
Cdd:MTH00199  344 LTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 15-337 7.01e-15

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 74.98  E-value: 7.01e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  15 VVGTILSISSNSWFGVWMGLEINLLSFIPLM-VNNKNMMVNESSIKYFIVQAMASTMLLFSILLI----------QMNTP 83
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslnfeDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  84 TGWEEQLIP-----TMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIA---PMMILSYCIQMSM------F 149
Cdd:TIGR01770 192 LSNGMLNISllllgIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFGFseawqiF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 150 TFTIIILSIIIGAMGGLNQTSLRQILAYSSISHLGW-MISSLIISENVWE---LYFIIYSLLSLVMVLIFKQMNLFFLNQ 225
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEGIKavlFYIFIYALMSLGAFGVLSLLRSYKDEW 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 226 IYSASNMKTEIK------FMMFLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMRIsfsALIM 299
Cdd:TIGR01770 352 IEYISDFAGLFKtnpilaILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV---VKVM 428

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1896070013 300 SYTENS--WLINKKNQTTTFILPMTVMISTLGLISTSILI 337
Cdd:TIGR01770 429 YFDKPErrIPSNPQSKAQSLLLSISALFILFLGLFPSLIL 468
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-292 2.09e-13

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 70.53  E-value: 2.09e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013   8 LLFLSTLvvGTILSISSNSWFGVWMGLEinLLSfIPLMV----NNKNMMVNESSIKYFIVQAMASTMLLFSILL------ 77
Cdd:COG1007   107 LLLFATL--GMMLMASANDLLTLFLGLE--LLS-LSLYVlvafRRDDRRSSEAALKYFLLGALSSGFLLYGISLlygatg 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  78 ------IQMNTPTGWEEQLIPTM---MISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILsycIQMSM 148
Cdd:COG1007   182 slnlagIAAALAAGGANSPLLLLglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAAL---LRLLV 258

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 149 FTFTIIILSIII------------GAMGGLNQTSLRQILAYSSISHLGWMISSLII-SENVWE---LYFIIYSLlslvmv 212
Cdd:COG1007   259 EAFPGLAADWQLllavlavlsmtvGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAgTPLGVSaalFYLLAYLF------ 332

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 213 lifkqMNL---FFLNQIYSASNMKTEIK-------------FMMFLSLLSLGGLPPFLGFLPKWIVMQSLIENNLSILMA 276
Cdd:COG1007   333 -----MNLgafAVILLLSRKGGEAEEIEdlaglarrspllaLAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAV 407

                         330
                  ....*....|....*.
gi 1896070013 277 FMIVLTTITLYYYMRI 292
Cdd:COG1007   408 IAVLNSVISAYYYLRV 423
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-292 8.09e-10

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 59.87  E-value: 8.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  16 VGTILSISSNSWFGVWMGLEINLLSFIPL---------MVNNKNMMVNESSIKYFIVQAMASTMLLF------------- 73
Cdd:MTH00198  199 LGGLLLIESANWLTIYLALEFQTLALFILagegsqpgsHFPSPGNTPPESGLKYWILGAMSSGFYLFgcalyfgftgneg 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  74 ---SILLIQMNTPTGWEEQ-LIPTMMISSSLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILSYCIQMSMF 149
Cdd:MTH00198  279 mlgTILSATLETTNIELRQgSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKL 358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 150 TFTIIILSIIIGAMGGLNQTSLRQILAYSSISHLGWMIssLIISENVWE---------LYFIIYSLLSLVMVLIF----- 215
Cdd:MTH00198  359 LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL--IGVSAGTYEslqaswtyaVTYLVSALASFTVICTLeefgt 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 216 -------KQMNLFFLNQIYSASNM------KTEIKFMMFLSLLSLGGLPPFLGFLPKWIVMQSLIE----NNLSI--LMA 276
Cdd:MTH00198  437 rtptsrqRDGSFGNYNLVRRLVDLtilsrgQPYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKiafsSSLSIyyLVA 516

                         330
                  ....*....|....*..
gi 1896070013 277 -FMIVLTTITLYYYMRI 292
Cdd:MTH00198  517 lFAIICTCISAFYYIRI 533
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-292 4.88e-06

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 47.83  E-value: 4.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  10 FLSTLVVGTILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQMNTPT----- 84
Cdd:COG0651   112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTlnmad 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  85 --GWEEQLIPTMMISSSLLL------KIGAAPFHFWFPEVMGSSEWFNCLIL---MTwqKIAPMMILSycIQMSMFTFTI 153
Cdd:COG0651   192 laARLAELDPGLLLAAFALLlvgfgiKAALFPLHFWLPDAYPAAPSPVSALLsglLT--KVGVYAILR--VLTLLFGADP 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 154 IILSII-----------IGAMGGLNQTSLRQILAYSSISHLGWMISSLIISeNVWELYFIIYSLL--SLVMVLIFkqM-- 218
Cdd:COG0651   268 ALFLGTlllvlglltmlVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLG-TPLGLAGALFHLLnhALAKALLF--Laa 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 219 -NLFFLNQIYSASNMKTEIKFMMFLSLLSLGGLPP------FLGFLPKWIVMQSLIENNLSILMAFMIVLTTITLYYYMR 291
Cdd:COG0651   345 gAIERATGTRDLDKLGGLGKRMPLTAAAFLIGALAlaglppLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVR 424


                  .
gi 1896070013 292 I 292
Cdd:COG0651   425 I 425
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 55-336 8.56e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 44.32  E-value: 8.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  55 ESSIKYFIVQAMASTMLLFSILLI--QMNTPT-----------GWEEQLIPTMMISSSLLLKIGAAPFHFWFPEVMGSS- 120
Cdd:PRK08376  172 EAGIKYMFVGSLASSMVLLGIALLygQYGTLNmaylavkmsenPTVVAKIALALFIAGLAMKSGAVPVHMWLPDAYPAAp 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 121 EWFNCLILMTWQ----KIAPMMILSYCIQMSMFTF-----TIIILSIIIGAMGGLNQTSLRQILAYSSISHLGWMISSLI 191
Cdd:PRK08376  252 SSISAMLLVIKQaglyALARVLFSIYGPAINLATVgwviiILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLGLG 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 192 ISENVWE---------------LYFII-----YSLLSLVMVLIFKQMNLFFLNQIYS-ASNM-KTEIKFMMflSLLSLGG 249
Cdd:PRK08376  332 VGLAALGdpamasygeialaggIYHIVnhalyKALLFLTAGAVIYETGTRNLNELGGlARTMpKTTIAFLI--GAAAIVG 409

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 250 LPPFLGFLPKWIVMQSLIENNlSILMAFMIVLTTITLYYYMRISFSALIMSYTENswLINKKNQTTTFILPM---TVMIS 326
Cdd:PRK08376  410 LPPFNGFASKWLIYESSALFN-PILGVIAMIGSVLTLASFVKVFHTAFFGPPSEK--VMNVKEPPKPMLVPMlilAIAII 486

                         330
                  ....*....|
gi 1896070013 327 TLGLISTSIL 336
Cdd:PRK08376  487 GMGLFPWQIS 496
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 34-187 4.66e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 38.71  E-value: 4.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  34 LEINLLSFIPLMVNNKNMMVNESSIKYFIVQAMASTMLLFSILLIQMNTPT-----------GWEEQLIPTMMISSSLLL 102
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTlnmadlagalaENPTVVTAFGFVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013 103 KIGAAPFHFWFPEVM-GSSEWFNCLILMTWQKIAPMMIlsYCIQMSMFTFTIIILSII-------------IGAMGGLNQ 168
Cdd:PRK08375  215 KAAVFPLHTWLPRAYpAAPPVVTALLSGLVTKVAVYAL--IRIYFTVFGGDFRFALGLgwllavlallsmlVGSLAALGQ 292

                         170
                  ....*....|....*....
gi 1896070013 169 TSLRQILAYSSISHLGWMI 187
Cdd:PRK08375  293 DDVKRVLAYSTVSQMGYIL 311
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 19-224 8.27e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 37.54  E-value: 8.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  19 ILSISSNSWFGVWMGLEINLLSFIPLMVNNKNMMvnessIKYFIVQAMASTMLLFSILLIQMntptgweeqliptmmisS 98
Cdd:MTH00091    8 FMSLNIFVWWSVFLLMTLLFVFLNKGMGSYSSLF-----NYFVLQESLGLLFLLFSFGYFQF-----------------L 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1896070013  99 SLLLKIGAAPFHFWFPEVMGSSEWFNCLILMTWQKIAPMMILSYCIQMSMFTFTIIILSIIIGAMggLNQTSLRQILAYS 178
Cdd:MTH00091   66 ILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQM--FLLKSYKNLLILS 143

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1896070013 179 SISHLGWMISSLIIS-ENVWELYFIIYSLLSLVMVLIFKQMNLFFLN 224
Cdd:MTH00091  144 STESFNWLILSFFFSfFNVFFLFFYYFLLMLFLIPKFNNVNKLNFVS 190
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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