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Conserved domains on  [gi|189571650|ref|NP_079047|]
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N-alpha-acetyltransferase 40 isoform 1 [Homo sapiens]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 10456837)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  15581578|10940244|9175471|27367672|26818562
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 80-188 6.11e-05

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


:

Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 41.35  E-value: 6.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189571650   80 NMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSSVPVAFSHFRFDvecGDEVLYCYEVQLE--SKVRRKGLGKFLIQ 157
Cdd:pfam00583   6 ELLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSII---DDEPPVGEIEGLAvaPEYRGKGIGTALLQ 82

                          90       100       110
                  ....*....|....*....|....*....|.
gi 189571650  158 ILQLMANSTQMKKVMLTVFKHNHGAYQFFRE 188
Cdd:pfam00583  83 ALLEWARERGCERIFLEVAADNLAAIALYEK 113
 
Name Accession Description Interval E-value
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 80-188 6.11e-05

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 41.35  E-value: 6.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189571650   80 NMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSSVPVAFSHFRFDvecGDEVLYCYEVQLE--SKVRRKGLGKFLIQ 157
Cdd:pfam00583   6 ELLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSII---DDEPPVGEIEGLAvaPEYRGKGIGTALLQ 82

                          90       100       110
                  ....*....|....*....|....*....|.
gi 189571650  158 ILQLMANSTQMKKVMLTVFKHNHGAYQFFRE 188
Cdd:pfam00583  83 ALLEWARERGCERIFLEVAADNLAAIALYEK 113
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 131-199 1.60e-04

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 39.64  E-value: 1.60e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 189571650 131 GDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFrEALQFEIDDSSP 199
Cdd:COG0456   10 GGDEAEIEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALY-EKLGFEEVGERP 77
 
Name Accession Description Interval E-value
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 80-188 6.11e-05

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 41.35  E-value: 6.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189571650   80 NMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSSVPVAFSHFRFDvecGDEVLYCYEVQLE--SKVRRKGLGKFLIQ 157
Cdd:pfam00583   6 ELLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSII---DDEPPVGEIEGLAvaPEYRGKGIGTALLQ 82

                          90       100       110
                  ....*....|....*....|....*....|.
gi 189571650  158 ILQLMANSTQMKKVMLTVFKHNHGAYQFFRE 188
Cdd:pfam00583  83 ALLEWARERGCERIFLEVAADNLAAIALYEK 113
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 131-199 1.60e-04

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 39.64  E-value: 1.60e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 189571650 131 GDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFrEALQFEIDDSSP 199
Cdd:COG0456   10 GGDEAEIEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALY-EKLGFEEVGERP 77
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
85-217 2.77e-04

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 40.36  E-value: 2.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189571650  85 YEQSEWGWKDREKR-EEMTDDRAWYLIAWENSSVpVAFSHF-RFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLM 162
Cdd:COG1247   30 FETEPPSEEEREAWfAAILAPGRPVLVAEEDGEV-VGFASLgPFRPRPAYRGTAEESIYVDPDARGRGIGRALLEALIER 108

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 189571650 163 ANSTQMKKVMLTVFKHNHGAYQFFrEALQFEIDDSSPSMSGCCGEDCSYEILSRR 217
Cdd:COG1247  109 ARARGYRRLVAVVLADNEASIALY-EKLGFEEVGTLPEVGFKFGRWLDLVLMQKR 162
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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