NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1893887626|ref|WP_185747779|]
View 

MULTISPECIES: methyl-accepting chemotaxis protein [unclassified Bosea (in: a-proteobacteria)]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 11435591)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
26-555 4.42e-49

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


:

Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 177.91  E-value: 4.42e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  26 LSRQIALAAVVIVAVAIIFVVMAVARYNDSRTRSDLDQKATALTLMVANAAPSLILSRDNLTLGYILESLRRDPDFDAAI 105
Cdd:COG0840    17 LALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 106 VADDLVSLASAGRTEEARLSLTPRWLTSAVGEEPWRKLLSVPSVEIEDDVSVTKIQPVRVVDRQIGYVAVRFDKTRLVAR 185
Cdd:COG0840    97 ALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAA 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 186 ATWEQFVIIGLGLAVLIVLGPLLWFSLSRTMRPLRGMTNAIVSISDGDLDTPIDAqDRGDEIGAIARALGVLKIRLaeRA 265
Cdd:COG0840   177 AALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDV-DSKDEIGQLADAFNRMIENL--RE 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 266 ALEEKQTLSETERRARQQNVDGAIAMfrsevglaleafksnADRMQEASDGLARVAAESSERAARAADNAHgasgNVESA 345
Cdd:COG0840   254 LVGQVRESAEQVASASEELAASAEEL---------------AAGAEEQAASLEETAAAMEELSATVQEVAE----NAQQA 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 346 AQAAEEMGAAIREVEFQVRRVRTEIVEAASASRNTAGSVEALDETARAIGEVVNLIRDIAAQTNLLALNATIEAARAGEA 425
Cdd:COG0840   315 AELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEA 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 426 GRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMNAIETFA-------NSVAASIEQQALATGE 498
Cdd:COG0840   395 GRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVeeagealEEIVEAVEEVSDLIQE 474

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1893887626 499 IASGVAMASSSALSVSSDLSVLADSVEETGRSAEQVRGAAGEVATQAQRLDSTVDQF 555
Cdd:COG0840   475 IAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRF 531
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
26-555 4.42e-49

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 177.91  E-value: 4.42e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  26 LSRQIALAAVVIVAVAIIFVVMAVARYNDSRTRSDLDQKATALTLMVANAAPSLILSRDNLTLGYILESLRRDPDFDAAI 105
Cdd:COG0840    17 LALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 106 VADDLVSLASAGRTEEARLSLTPRWLTSAVGEEPWRKLLSVPSVEIEDDVSVTKIQPVRVVDRQIGYVAVRFDKTRLVAR 185
Cdd:COG0840    97 ALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAA 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 186 ATWEQFVIIGLGLAVLIVLGPLLWFSLSRTMRPLRGMTNAIVSISDGDLDTPIDAqDRGDEIGAIARALGVLKIRLaeRA 265
Cdd:COG0840   177 AALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDV-DSKDEIGQLADAFNRMIENL--RE 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 266 ALEEKQTLSETERRARQQNVDGAIAMfrsevglaleafksnADRMQEASDGLARVAAESSERAARAADNAHgasgNVESA 345
Cdd:COG0840   254 LVGQVRESAEQVASASEELAASAEEL---------------AAGAEEQAASLEETAAAMEELSATVQEVAE----NAQQA 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 346 AQAAEEMGAAIREVEFQVRRVRTEIVEAASASRNTAGSVEALDETARAIGEVVNLIRDIAAQTNLLALNATIEAARAGEA 425
Cdd:COG0840   315 AELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEA 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 426 GRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMNAIETFA-------NSVAASIEQQALATGE 498
Cdd:COG0840   395 GRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVeeagealEEIVEAVEEVSDLIQE 474

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1893887626 499 IASGVAMASSSALSVSSDLSVLADSVEETGRSAEQVRGAAGEVATQAQRLDSTVDQF 555
Cdd:COG0840   475 IAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRF 531
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 305-555 6.38e-39

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 143.20  E-value: 6.38e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  305 SNADRMQEASDGLARVAAESSERAARAADNAHGASGNVESAAQAAEEMGAAIREVEFQVRRVRTEIVEAASAsrntagsV 384
Cdd:smart00283  11 AGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAVSA-------V 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  385 EALDETARAIGEVVNLIRDIAAQTNLLALNATIEAARAGEAGRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATGQV 464
Cdd:smart00283  84 EELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEETNEA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  465 VG---------------------AIQNIAERMNAIETFANSVAASIEQQALATGEIASGVAmasssalsvssdlsVLADS 523
Cdd:smart00283 164 VAameessseveegvelveetgdALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAID--------------EIAQV 229

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1893887626  524 VEETGRSAEQVRGAAGEVATQAQRLDSTVDQF 555
Cdd:smart00283 230 TQETAAMSEEISAAAEELSGLAEELDELVERF 261
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 323-542 5.50e-34

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 127.74  E-value: 5.50e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 323 ESSERAARAADNAHGASGNVESAAQAAEEMGAAIREVEFQVRRVRTEIVEAASAsrntagsVEALDETARAIGEVVNLIR 402
Cdd:cd11386     2 ELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSA-------VEELEESSAEIGEIVEVID 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 403 DIAAQTNLLALNATIEAARAGEAGRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMNAIETFA 482
Cdd:cd11386    75 DIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELV 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 483 NSVAASIEQQALATGEIASGVAmasssalsvssdlsVLADSVEETGRSAEQVRGAAGEVA 542
Cdd:cd11386   155 EETGRAFEEIVASVEEVADGIQ--------------EISAATQEQSASTQEIAAAVEEIA 200
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
198-555 3.62e-24

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 106.31  E-value: 3.62e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 198 LAVLIVLGPLLWfslSRTM--RPLRGMTNAIVSISDGDLDTPIDAQDRgDEIGAIARALGVLKirlaeraaleekQTLSE 275
Cdd:PRK09793  198 VAAIYISSALWW---TRKMivQPLAIIGSHFDSIAAGNLARPIAVYGR-NEITAIFASLKTMQ------------QALRG 261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 276 TERRARQqnvdGAIAMfrsEVGLALEAFKSN--ADRMQEASDGLARVAAESSERAA---RAADNAHGASGNVESAAQAAE 350
Cdd:PRK09793  262 TVSDVRK----GSQEM---HIGIAEIVAGNNdlSSRTEQQAASLAQTAASMEQLTAtvgQNADNARQASELAKNAATTAQ 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 351 EMGAairevefQVRRVRTEIVEAASASRNtagsvealdetaraIGEVVNLIRDIAAQTNLLALNATIEAARAGEAGRGFA 430
Cdd:PRK09793  335 AGGV-------QVSTMTHTMQEIATSSQK--------------IGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFA 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 431 VVASEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMNAIETFANSVAASIEQQALATGEIASGVAMASSSA 510
Cdd:PRK09793  394 VVAGEVRNLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMTDIVSSVTRVNDIMGEIASASEEQRRGIEQVAQAV 473

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1893887626 511 LSVSSDLSVLADSVEETGRSAEQvrgaageVATQAQRLDSTVDQF 555
Cdd:PRK09793  474 SQMDQVTQQNASLVEEAAVATEQ-------LANQADHLSSRVAVF 511
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 379-503 2.89e-22

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 94.04  E-value: 2.89e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 379 NTAGSVEALDETARAIGEVVNLIRDIAAQTNLLALNATIEAARAGEAGRGFAVVASEVKSLAAQTADATDRIVSQVAAIQ 458
Cdd:pfam00015  20 NVVGQMEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQAAKEIEALIIEIQ 99

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1893887626 459 GATGQVVGAIQNI--------------AERMNAIETFANSVAASIEQQALATGEIASGV 503
Cdd:pfam00015 100 KQTNDSTASIESTrqrvevgstivestGEALKEIVDAVAEIADIVQEIAAASDEQSAGI 158
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
26-555 4.42e-49

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 177.91  E-value: 4.42e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  26 LSRQIALAAVVIVAVAIIFVVMAVARYNDSRTRSDLDQKATALTLMVANAAPSLILSRDNLTLGYILESLRRDPDFDAAI 105
Cdd:COG0840    17 LALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 106 VADDLVSLASAGRTEEARLSLTPRWLTSAVGEEPWRKLLSVPSVEIEDDVSVTKIQPVRVVDRQIGYVAVRFDKTRLVAR 185
Cdd:COG0840    97 ALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAA 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 186 ATWEQFVIIGLGLAVLIVLGPLLWFSLSRTMRPLRGMTNAIVSISDGDLDTPIDAqDRGDEIGAIARALGVLKIRLaeRA 265
Cdd:COG0840   177 AALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDV-DSKDEIGQLADAFNRMIENL--RE 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 266 ALEEKQTLSETERRARQQNVDGAIAMfrsevglaleafksnADRMQEASDGLARVAAESSERAARAADNAHgasgNVESA 345
Cdd:COG0840   254 LVGQVRESAEQVASASEELAASAEEL---------------AAGAEEQAASLEETAAAMEELSATVQEVAE----NAQQA 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 346 AQAAEEMGAAIREVEFQVRRVRTEIVEAASASRNTAGSVEALDETARAIGEVVNLIRDIAAQTNLLALNATIEAARAGEA 425
Cdd:COG0840   315 AELAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEA 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 426 GRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMNAIETFA-------NSVAASIEQQALATGE 498
Cdd:COG0840   395 GRGFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVeeagealEEIVEAVEEVSDLIQE 474

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1893887626 499 IASGVAMASSSALSVSSDLSVLADSVEETGRSAEQVRGAAGEVATQAQRLDSTVDQF 555
Cdd:COG0840   475 IAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRF 531
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 305-555 6.38e-39

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 143.20  E-value: 6.38e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  305 SNADRMQEASDGLARVAAESSERAARAADNAHGASGNVESAAQAAEEMGAAIREVEFQVRRVRTEIVEAASAsrntagsV 384
Cdd:smart00283  11 AGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAVSA-------V 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  385 EALDETARAIGEVVNLIRDIAAQTNLLALNATIEAARAGEAGRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATGQV 464
Cdd:smart00283  84 EELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEETNEA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  465 VG---------------------AIQNIAERMNAIETFANSVAASIEQQALATGEIASGVAmasssalsvssdlsVLADS 523
Cdd:smart00283 164 VAameessseveegvelveetgdALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAID--------------EIAQV 229

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1893887626  524 VEETGRSAEQVRGAAGEVATQAQRLDSTVDQF 555
Cdd:smart00283 230 TQETAAMSEEISAAAEELSGLAEELDELVERF 261
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 323-542 5.50e-34

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 127.74  E-value: 5.50e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 323 ESSERAARAADNAHGASGNVESAAQAAEEMGAAIREVEFQVRRVRTEIVEAASAsrntagsVEALDETARAIGEVVNLIR 402
Cdd:cd11386     2 ELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSA-------VEELEESSAEIGEIVEVID 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 403 DIAAQTNLLALNATIEAARAGEAGRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMNAIETFA 482
Cdd:cd11386    75 DIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELV 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 483 NSVAASIEQQALATGEIASGVAmasssalsvssdlsVLADSVEETGRSAEQVRGAAGEVA 542
Cdd:cd11386   155 EETGRAFEEIVASVEEVADGIQ--------------EISAATQEQSASTQEIAAAVEEIA 200
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
198-555 3.62e-24

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 106.31  E-value: 3.62e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 198 LAVLIVLGPLLWfslSRTM--RPLRGMTNAIVSISDGDLDTPIDAQDRgDEIGAIARALGVLKirlaeraaleekQTLSE 275
Cdd:PRK09793  198 VAAIYISSALWW---TRKMivQPLAIIGSHFDSIAAGNLARPIAVYGR-NEITAIFASLKTMQ------------QALRG 261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 276 TERRARQqnvdGAIAMfrsEVGLALEAFKSN--ADRMQEASDGLARVAAESSERAA---RAADNAHGASGNVESAAQAAE 350
Cdd:PRK09793  262 TVSDVRK----GSQEM---HIGIAEIVAGNNdlSSRTEQQAASLAQTAASMEQLTAtvgQNADNARQASELAKNAATTAQ 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 351 EMGAairevefQVRRVRTEIVEAASASRNtagsvealdetaraIGEVVNLIRDIAAQTNLLALNATIEAARAGEAGRGFA 430
Cdd:PRK09793  335 AGGV-------QVSTMTHTMQEIATSSQK--------------IGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFA 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 431 VVASEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMNAIETFANSVAASIEQQALATGEIASGVAMASSSA 510
Cdd:PRK09793  394 VVAGEVRNLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMTDIVSSVTRVNDIMGEIASASEEQRRGIEQVAQAV 473

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1893887626 511 LSVSSDLSVLADSVEETGRSAEQvrgaageVATQAQRLDSTVDQF 555
Cdd:PRK09793  474 SQMDQVTQQNASLVEEAAVATEQ-------LANQADHLSSRVAVF 511
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 379-503 2.89e-22

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 94.04  E-value: 2.89e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 379 NTAGSVEALDETARAIGEVVNLIRDIAAQTNLLALNATIEAARAGEAGRGFAVVASEVKSLAAQTADATDRIVSQVAAIQ 458
Cdd:pfam00015  20 NVVGQMEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQAAKEIEALIIEIQ 99

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1893887626 459 GATGQVVGAIQNI--------------AERMNAIETFANSVAASIEQQALATGEIASGV 503
Cdd:pfam00015 100 KQTNDSTASIESTrqrvevgstivestGEALKEIVDAVAEIADIVQEIAAASDEQSAGI 158
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 186-553 3.10e-19

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 91.22  E-value: 3.10e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 186 ATWeQFVIIGLGLAVLIVLgplLWFSLSRTM-RPLRGMTNAIVSISDGDLDTPIDAQDRgDEIGAIARALGVLKirlaer 264
Cdd:PRK15048  190 AQW-QLAVIALVVVLILLV---AWYGIRRMLlTPLAKIIAHIREIAGGNLANTLTIDGR-SEMGDLAQSVSHMQ------ 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 265 aaleekQTLSETERRARQQNvdGAIAMFRSEVGLALEAFKSNADRMQEASDGLARVAAESSERAARAADNAHGASGNVES 344
Cdd:PRK15048  259 ------RSLTDTVTHVREGS--DAIYAGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQS 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 345 AAQAAEEMGAAIREVefqvrrVRTeiveaasasrntagsVEALDETARAIGEVVNLIRDIAAQTNLLALNATIEAARAGE 424
Cdd:PRK15048  331 ASDTAQHGGKVVDGV------VKT---------------MHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGE 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 425 AGRGFAVVASEVKSLAAQTADATDRI-------VSQV---AAIQGATGQ----VVGAIQNIAERMNAIETFANSVAASIE 490
Cdd:PRK15048  390 QGRGFAVVAGEVRNLASRSAQAAKEIkaliedsVSRVdtgSVLVESAGEtmnnIVNAVTRVTDIMGEIASASDEQSRGID 469

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1893887626 491 QQALATGEIASGVAMASSSALSVSSDLSVLADSVEETGRSAEQVRGAAGEVATQAQRLDSTVD 553
Cdd:PRK15048  470 QVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLAASPLTNKPQTPSRPAS 532
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
178-499 1.21e-18

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 89.24  E-value: 1.21e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 178 DKTRLVARATWeqfVIIGLGLAVLIVLgPLLWFSLSRTM-RPLRGMTNAIVSISDGDLDTPIDAqDRGDEIGAIARALGV 256
Cdd:PRK15041  184 DNNASYSQAMW---ILVGVMIVVLAVI-FAVWFGIKASLvAPMNRLIDSIRHIAGGDLVKPIEV-DGSNEMGQLAESLRH 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 257 LKIRLAeraaleekQTLSETerrarqQNVDGAIAMFRSEVGLALEAFKSnadRMQEASDGLARVAAESSERAA---RAAD 333
Cdd:PRK15041  259 MQGELM--------RTVGDV------RNGANAIYSGASEIATGNNDLSS---RTEQQAASLEETAASMEQLTAtvkQNAE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 334 NAHGASGNVESAAQAAEEMGAAIREVefqvrrVRTeiveaasaSRNTAGSvealdetARAIGEVVNLIRDIAAQTNLLAL 413
Cdd:PRK15041  322 NARQASHLALSASETAQRGGKVVDNV------VQT--------MRDISTS-------SQKIADIISVIDGIAFQTNILAL 380

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 414 NATIEAARAGEAGRGFAVVASEVKSLAAQTADATDRI-------VSQVAAiqGAT---------GQVVGAIQNIAERMNA 477
Cdd:PRK15041  381 NAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIksliedsVGKVDV--GSTlvesagetmAEIVSAVTRVTDIMGE 458

                         330       340
                  ....*....|....*....|..
gi 1893887626 478 IETFANSVAASIEQQALATGEI 499
Cdd:PRK15041  459 IASASDEQSRGIDQVGLAVAEM 480
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
26-561 1.35e-08

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 57.82  E-value: 1.35e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  26 LSRQIALAAVVIVAVAIIFVVMAVARYNDSRTRSDLDQKATALTLMVANAAPSLILSRDNLTLGYILESLRRDPDFDAAI 105
Cdd:COG2770    47 LALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLL 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 106 VADDLVSLASAGRTEEARLSLTPRWLTSAVGEEPWRKLLSVPSVEIEDDVSVTKIQPVRVVDRQIGYVAVRFDKTRLVAR 185
Cdd:COG2770   127 LLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEA 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 186 ATWEQFVIIGLGLAVLIVLGPLLWFSLSRTMRPLRGMTNAIVSISDGDLDTPIDaQDRGDEIGAIARALGVLKIRLAERA 265
Cdd:COG2770   207 ALAALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIP-VSRKDEIGELARAFNRMADSLRESI 285

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 266 ALEEKQTLSETERRARQQNVDGAIAMFRSEVGLALEAFKSNADRMQEASDGLARVAAESSERAARAADNAHGASGNVESA 345
Cdd:COG2770   286 EEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLAL 365

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 346 AQAAEEMGAAIREVEFQVRRVRTEIVEAASASRNTAGSVEALDETARAIGEVVNLIRDIAAQTNLLALNATIEAARAGEA 425
Cdd:COG2770   366 ELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAI 445

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 426 GRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMNAIETFANSVAASIEQQALATGEIASGVAM 505
Cdd:COG2770   446 AAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAEELAEELLLLEGLLLLLLLEAEA 525

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1893887626 506 ASSSALSVSSDLSVLADSVEETGRSAEQVRGAAGEVATQAQRLDSTVDQFLRNVAA 561
Cdd:COG2770   526 LEVAEELLELEEAALLLAAAAELAALLALLLALAAVEAAALLLAALLLAAVAALLE 581
YesM COG2972
Sensor histidine kinase YesM [Signal transduction mechanisms];
51-282 6.08e-06

Sensor histidine kinase YesM [Signal transduction mechanisms];


Pssm-ID: 442211 [Multi-domain]  Cd Length: 445  Bit Score: 48.86  E-value: 6.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  51 RYNDSRTRSDLDQKATALTLMVANAAPSLILSRDNLTLGYILESLRRDPDFDAAIVADDLVSLASAGRTEEARLSLTPRW 130
Cdd:COG2972    17 LLLLVLLILLLSLLLIILLLLLLLILLLLLLILLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLILLLLLLLLLLLILL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 131 LTSAVGEEPWRKLLSVPSVEIEDDVSVTKIQPVRVVDRQIGYVAVRFDKTRLVARATWEQFVIIGLGLAVLIVLGPLLWF 210
Cdd:COG2972    97 LSLLLLLALILLLALLLLLSILLLILGLLLIILLLLSLLGWTLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYL 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1893887626 211 SLSRTMRPLRGMTNAIVSISDGDLDTPIDaqDRGDEIGAIARALG--VLKIRLAERAALEEKQTLSETERRARQ 282
Cdd:COG2972   177 LSRSITRPIKRLKKAMKKVEKGDLVRLEV--SGNDEIGILARSFNemVERIKELIEEVYELELEKKEAELKALQ 248
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
 186-276 1.09e-05

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 48.03  E-value: 1.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 186 ATWEQFVIIGLGLAVLIVLGPLLWFSLS---RTMRPLRGMTNAIVSISDGDLDTPIDaQDRGDEIGAIARALGVLKIRLA 262
Cdd:COG5000     1 SGLQILFLLLLLLIALLLLLLALWLALLlarRLTRPLRRLAEATRAVAAGDLSVRLP-VTGDDEIGELARAFNRMTDQLK 79

                          90
                  ....*....|....*
gi 1893887626 263 E-RAALEEKQTLSET 276
Cdd:COG5000    80 EqREELEERRRYLET 94
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 216-254 1.95e-05

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 42.05  E-value: 1.95e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1893887626 216 MRPLRGMTNAIVSISDGDLDTPIDAQdRGDEIGAIARAL 254
Cdd:cd06225     1 TRPLRRLTEAARRIAEGDLDVRVPVR-SKDEIGELARAF 38
HAMP pfam00672
HAMP domain;
214-263 2.75e-05

HAMP domain;


Pssm-ID: 459898 [Multi-domain]  Cd Length: 53  Bit Score: 41.84  E-value: 2.75e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1893887626 214 RTMRPLRGMTNAIVSISDGDLDTPIDAqDRGDEIGAIARALGVLKIRLAE 263
Cdd:pfam00672   5 RILRPLRRLAEAARRIASGDLDVRLPV-SGRDEIGELARAFNQMAERLRE 53
HAMP smart00304
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
214-266 3.89e-05

HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;


Pssm-ID: 197640 [Multi-domain]  Cd Length: 53  Bit Score: 41.46  E-value: 3.89e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1893887626  214 RTMRPLRGMTNAIVSISDGDLDTPIDAqDRGDEIGAIARALGVLKIRLAERAA 266
Cdd:smart00304   2 RLLRPLRRLAEAAQRIADGDLTVRLPV-DGRDEIGELARAFNEMADRLEETIA 53
COG4192 COG4192
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ...
 191-284 5.91e-05

Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];


Pssm-ID: 443346 [Multi-domain]  Cd Length: 640  Bit Score: 45.83  E-value: 5.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 191 FVIIGLGLAVLIVLGPLLWFSLSRTM-RPLRGMTNAIVSISDGDLDTPIdAQDRGDEIGAIARALGVLKIRLAERAALEE 269
Cdd:COG4192   326 ILLLAIALLSLLLAVLINYFYVRRRLvKRLNALSDAMAAIAAGDLDVPI-PVDGNDEIGRIARLLRVFRDQAIEKTQELE 404

                          90
                  ....*....|....*
gi 1893887626 270 kqtlSETERRARQQN 284
Cdd:COG4192   405 ----TEIEERKRIEK 415
NarQ COG3850
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ...
 79-480 3.38e-04

Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];


Pssm-ID: 443059 [Multi-domain]  Cd Length: 448  Bit Score: 43.33  E-value: 3.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626  79 LILSRDNLTLGYILESLRRDPDFDAAIVADDLVSLASAGRTEEARLSLTPRWLTSAVGEEPWRKLLSVPSVEIEDDVSVT 158
Cdd:COG3850     7 LALALLRLLLALLALLLLALLLLSLLALLLLLERTLLRLLSLLASAGLLAALLAALLLLLSLGLLALLLALLLLLLLLLL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 159 KIQPVRVVDRQIGYVAVRFDKTRLVARATWEQFVIIGLGLAVLIVLGpLLWFSLSRTMRPLRGMTNAIVSISDGDLDTPI 238
Cdd:COG3850    87 AALLSLLLLLLLLLLLLLLLLLLLLAAAINRKLALLRLLLALLLALL-LAYLLRRRIVRPLRRLTQAAERIARGDFDARV 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 239 DAQdRGDEIGAIARALGVLKIRLAERAALEEKQTLSETERRARQQNVDGAIAMFRSEVGLALEAFKSNADRMQEASDGLA 318
Cdd:COG3850   166 PVS-GRDELGTLARAFNRMADELQELYAELEEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 319 RVAAESSERAARAADNAHGASGNVESAAQAAEEMGAAIREVEFQVRRVRTEIVEAASASRNTAGSVEALDETARAIGEVV 398
Cdd:COG3850   245 QDALAESELLALNILAGLLELLLALLLLLLASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIA 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 399 NLIRDIAAQTNLLALNATIEAARAGEAGRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMNAI 478
Cdd:COG3850   325 NASLLLIALASVVAALLELASILALQAALEAAAAGAALAAAAAAAGLARALAQAGADAAEALGLLAEASEGAAGQGAGLV 404


                  ..
gi 1893887626 479 ET 480
Cdd:COG3850   405 DV 406
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 239-548 6.90e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 6.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 239 DAQDRGDEIGAIARALGVLKIRLAERAALEEKQTLSETERRARQQNVDGAIAMFRSEVGLALEAFKSNADRMQEASDGLA 318
Cdd:COG1196   335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 319 RVAAESSERAARAADNAHGASgNVESAAQAAEEMGAAIREVEFQVRRVRTEIVEAASASRNTAGSVEALDETARAIGEVV 398
Cdd:COG1196   415 RLERLEEELEELEEALAELEE-EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 399 NLIRDIAAQTNLLALNATIEAARAGEAGRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMNAI 478
Cdd:COG1196   494 LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGR 573

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1893887626 479 ETF---ANSVAASIEQQALATGEIASGVAMASSSALSVSSDLSVLADSVEETGRSAEQVRGAAGEVATQAQRL 548
Cdd:COG1196   574 ATFlplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL 646
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 241-550 7.91e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 7.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 241 QDRGDEIGAIARALgVLKIRLAERAALEEKQTLSETERR---ARQQNVDGAIAMFRSEVGLALEAFKSNADRMQEASDGL 317
Cdd:COG1196   219 KEELKELEAELLLL-KLRELEAELEELEAELEELEAELEeleAELAELEAELEELRLELEELELELEEAQAEEYELLAEL 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 318 ARVAAESSERAARAADnahgasgnvesAAQAAEEMGAAIREVEFQVRRVRTEIVEAASASRNTAGSVEALDETARaigev 397
Cdd:COG1196   298 ARLEQDIARLEERRRE-----------LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA----- 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 398 vnlirdiAAQTNLLALNATIEAARAgeagrgfavvasEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMNA 477
Cdd:COG1196   362 -------EAEEALLEAEAELAEAEE------------ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1893887626 478 IETFANSVAASIEQQALATGEIASGVAMASSSALSVSSDLSVLADSVEETGRSAEQVRGAAGEVATQAQRLDS 550
Cdd:COG1196   423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 249-542 1.53e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 1.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 249 AIARALGVLKIRLAERAALEEKQTLSETERRARQQNVDGAIAMFR---SEVGLALEAFKSNADRMQEASDGLARVAAESS 325
Cdd:COG1196   247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYellAELARLEQDIARLEERRRELEERLEELEEELA 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 326 E---RAARAADNAHGASGNVESAAQAAEEMGAAIREVEFQVRRVRTEIVEAASASRNTAgsVEALDETARAIGEVVNLIR 402
Cdd:COG1196   327 EleeELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA--EELLEALRAAAELAAQLEE 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 403 DIAAQTNLLALNATIEAARAG------EAGRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATGQVVGAIQNIAERMN 476
Cdd:COG1196   405 LEEAEEALLERLERLEEELEEleealaELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1893887626 477 AIETFANSVAASIEQQALATGEIASGVAMASSSALSVSSDLSVLADSVEETGRSAEQVRGAAGEVA 542
Cdd:COG1196   485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQN 550
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 240-561 1.78e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 1.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 240 AQDRGDEIGAIARALGVLKIRLAERAALEEKQTLSETERRARQQNVDGAIAMFRSEVGLALEAFKSNADRMQEASDGLAR 319
Cdd:COG1196   409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 320 VAAESSERAARAADNAHGASGNVESAAQAAEEMGAAIREVEFQVRRVRTEIVEAASASRNTAGSVEALDETARAIGEvvn 399
Cdd:COG1196   489 AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY--- 565

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 400 LIRDIAAQTNLLALNAtIEAARAGEAGRGFAVVASEVKSLAAQTADATDRIVSQVAAIQGATgQVVGAIQNIAERMNAIE 479
Cdd:COG1196   566 LKAAKAGRATFLPLDK-IRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRT-LVAARLEAALRRAVTLA 643

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1893887626 480 TFANSVAASIEQQALATGEIASGVAMASSSALSVSSDLSVLADSVEETGRSAEQVRGAAGEVATQAQRLDSTVDQFLRNV 559
Cdd:COG1196   644 GRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEE 723


                  ..
gi 1893887626 560 AA 561
Cdd:COG1196   724 EA 725
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH