|
Name |
Accession |
Description |
Interval |
E-value |
| HrpA |
COG1643 |
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]; |
67-525 |
1.05e-172 |
|
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441249 [Multi-domain] Cd Length: 836 Bit Score: 530.04 E-value: 1.05e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWitGRYPTKKaVACTQPRRVAAMSVAQRVSEEMDVELGQE 146
Cdd:COG1643 10 LPVSAVLPELLAALRAHQVVVLAAPPGAGKTTQLPLALLEL--GWGAGGR-IGMLEPRRLAARAAAERMAEELGEPVGET 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 147 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEII-KQRMDLKIVVMSATL 225
Cdd:COG1643 87 VGYRVRFEDKVSAATRIEVVTEGILLRELQRDPELEGVDTVIFDEFHERSLNADLLLALLLDLQpALRPDLKLLVMSATL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 226 DAGKFQEYFSKAPLMTVPGRTHPVEIFYTP--EPERDYLEAAIRTVIQIHmcEEVEGDILLFLTGQEEIEEACKRIQREv 303
Cdd:COG1643 167 DAERFARLLGDAPVIESSGRTYPVEVRYRPlpADERDLEDAVADAVREAL--AEEPGDILVFLPGEREIRRTAEALRGR- 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 304 dgLGPDVgELRciPLYSTLPPNLQQRIFDPPPPKRangaigRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRV 383
Cdd:COG1643 244 --LPPDT-EIL--PLYGRLSAAEQDRAFAPAPHGR------RRIVLATNIAETSLTVPGIRYVIDSGLARIPRYDPRSGV 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 384 ESLLVTAISKASAQQRAGRAGRTKPGKCFRLYTEKAYANeMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAP 463
Cdd:COG1643 313 TRLPTERISQASANQRAGRAGRLAPGICYRLWSEEDFAR-RPAFTDPEILRADLASLILELAAWGLGDPEDLPFLDPPPA 391
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1892353677 464 ETLMRALELLNYLAALDDDGNLTDLGSMMAEFPLDPQLAKMVMASCDFNCSNEVLSITAMLS 525
Cdd:COG1643 392 RAIADARALLQELGALDADGRLTPLGRALARLPLDPRLARMLLAAAELGCLREAAILAALLS 453
|
|
| HrpA |
COG1643 |
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]; |
543-937 |
4.99e-149 |
|
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441249 [Multi-domain] Cd Length: 836 Bit Score: 467.64 E-value: 4.99e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWitGRYPTKKaVACTQPRRVAAMSVAQRVSEEMDVELGQE 622
Cdd:COG1643 10 LPVSAVLPELLAALRAHQVVVLAAPPGAGKTTQLPLALLEL--GWGAGGR-IGMLEPRRLAARAAAERMAEELGEPVGET 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 623 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEII-KQRMDLKIVVMSATL 701
Cdd:COG1643 87 VGYRVRFEDKVSAATRIEVVTEGILLRELQRDPELEGVDTVIFDEFHERSLNADLLLALLLDLQpALRPDLKLLVMSATL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 702 DAGKFQEYFSKAPLMTVPGRTHPVEIFYTP--EPERDYLEAAIRTVIQIHmcEEVEGDILLFLTGQEEIEEACKRIQREv 779
Cdd:COG1643 167 DAERFARLLGDAPVIESSGRTYPVEVRYRPlpADERDLEDAVADAVREAL--AEEPGDILVFLPGEREIRRTAEALRGR- 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 780 dgLGPDVgELRciPLYSTLPPNLQQRIFDPPPPKRangaigRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRV 859
Cdd:COG1643 244 --LPPDT-EIL--PLYGRLSAAEQDRAFAPAPHGR------RRIVLATNIAETSLTVPGIRYVIDSGLARIPRYDPRSGV 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1892353677 860 ESLLVTAISKASAQQRAGRAGRTKPGKCFRLYTEKAYANeMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPP 937
Cdd:COG1643 313 TRLPTERISQASANQRAGRAGRLAPGICYRLWSEEDFAR-RPAFTDPEILRADLASLILELAAWGLGDPEDLPFLDPP 389
|
|
| DEAH_box_HrpA |
TIGR01967 |
RNA helicase HrpA; This model represents HrpA, one of two related but uncharacterized DEAH-box ... |
67-560 |
2.78e-131 |
|
RNA helicase HrpA; This model represents HrpA, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria and a few high-GC Gram-positive bacteria. HrpA is about 1300 amino acids long, while its paralog HrpB, also uncharacterized, is about 800 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. The HrpA/B homolog from Borrelia is 500 amino acids shorter but appears to be derived from HrpA rather than HrpB. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273900 [Multi-domain] Cd Length: 1283 Bit Score: 432.27 E-value: 2.78e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyptKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 146
Cdd:TIGR01967 66 LPVSAKREDIAEAIAENQVVIIAGETGSGKTTQLPKICLELGRGS---HGLIGHTQPRRLAARTVAQRIAEELGTPLGEK 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 147 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 226
Cdd:TIGR01967 143 VGYKVRFHDQVSSNTLVKLMTDGILLAETQQDRFLSRYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKIIITSATID 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 227 AGKFQEYFSKAPLMTVPGRTHPVEIFYTP------EPERDYLEAAIRTVIQihMCEEVEGDILLFLTGQEEIEEACKRIQ 300
Cdd:TIGR01967 223 PERFSRHFNNAPIIEVSGRTYPVEVRYRPlveeqeDDDLDQLEAILDAVDE--LFAEGPGDILIFLPGEREIRDAAEILR 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 301 REvdglgpDVGELRCIPLYSTLPPNLQQRIFDPpppkrangAIGRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPR 380
Cdd:TIGR01967 301 KR------NLRHTEILPLYARLSNKEQQRVFQP--------HSGRRIVLATNVAETSLTVPGIHYVIDTGTARISRYSYR 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 381 IRVESLLVTAISKASAQQRAGRAGRTKPGKCFRLYTEKAYaNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDP 460
Cdd:TIGR01967 367 TKVQRLPIEPISQASANQRKGRCGRVAPGICIRLYSEEDF-NSRPEFTDPEILRTNLASVILQMLALRLGDIAAFPFIEA 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 461 PAPETLMRALELLNYLAALDDD---GNLTDLGSMMAEFPLDPQLAKMVMASCDFNCSNEVLSITAMLS------------ 525
Cdd:TIGR01967 446 PDPRAIRDGFRLLEELGALDDDeaePQLTPIGRQLAQLPVDPRLARMLLEAHRLGCLQEVLIIASALSiqdprerpmekq 525
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 1892353677 526 --GKPFSARYFEL---FRKRIRLpvWEYKENFFKVISENQ 560
Cdd:TIGR01967 526 qaADQAHARFKDPrsdFLSRVNL--WRHIEEQRQALSANQ 563
|
|
| PRK11131 |
PRK11131 |
ATP-dependent RNA helicase HrpA; Provisional |
67-525 |
5.64e-130 |
|
ATP-dependent RNA helicase HrpA; Provisional
Pssm-ID: 182986 [Multi-domain] Cd Length: 1294 Bit Score: 429.09 E-value: 5.64e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEwiTGRyPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 146
Cdd:PRK11131 73 LPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICLE--LGR-GVKGLIGHTQPRRLAARTVANRIAEELETELGGC 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 147 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 226
Cdd:PRK11131 150 VGYKVRFNDQVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFILGYLKELLPRRPDLKVIITSATID 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 227 AGKFQEYFSKAPLMTVPGRTHPVEIFYTP------EPERDYLEAAIRTVIQihMCEEVEGDILLFLTGQEEIEEACKRIQ 300
Cdd:PRK11131 230 PERFSRHFNNAPIIEVSGRTYPVEVRYRPiveeadDTERDQLQAIFDAVDE--LGREGPGDILIFMSGEREIRDTADALN 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 301 REvdglgpDVGELRCIPLYSTLPPNLQQRIFDPpppkrangAIGRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPR 380
Cdd:PRK11131 308 KL------NLRHTEILPLYARLSNSEQNRVFQS--------HSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYR 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 381 IRVESLLVTAISKASAQQRAGRAGRTKPGKCFRLYTEKAYAN--EMQDntyPEILRSNLGTVVLQLKKLGIDDLVHFDFM 458
Cdd:PRK11131 374 TKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDDFLSrpEFTD---PEILRTNLASVILQMTALGLGDIAAFPFV 450
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1892353677 459 DPPAPETLMRALELLNYLAALDDDGN-----LTDLGSMMAEFPLDPQLAKMVMASCDFNCSNEVLSITAMLS 525
Cdd:PRK11131 451 EAPDKRNIQDGVRLLEELGAITTDEQasaykLTPLGRQLAQLPVDPRLARMVLEAQKHGCVREVMIITSALS 522
|
|
| DEAH_box_HrpA |
TIGR01967 |
RNA helicase HrpA; This model represents HrpA, one of two related but uncharacterized DEAH-box ... |
543-1120 |
2.70e-126 |
|
RNA helicase HrpA; This model represents HrpA, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria and a few high-GC Gram-positive bacteria. HrpA is about 1300 amino acids long, while its paralog HrpB, also uncharacterized, is about 800 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. The HrpA/B homolog from Borrelia is 500 amino acids shorter but appears to be derived from HrpA rather than HrpB. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273900 [Multi-domain] Cd Length: 1283 Bit Score: 418.79 E-value: 2.70e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyptKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 622
Cdd:TIGR01967 66 LPVSAKREDIAEAIAENQVVIIAGETGSGKTTQLPKICLELGRGS---HGLIGHTQPRRLAARTVAQRIAEELGTPLGEK 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 623 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 702
Cdd:TIGR01967 143 VGYKVRFHDQVSSNTLVKLMTDGILLAETQQDRFLSRYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKIIITSATID 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 703 AGKFQEYFSKAPLMTVPGRTHPVEIFYTP------EPERDYLEAAIRTVIQihMCEEVEGDILLFLTGQEEIEEACKRIQ 776
Cdd:TIGR01967 223 PERFSRHFNNAPIIEVSGRTYPVEVRYRPlveeqeDDDLDQLEAILDAVDE--LFAEGPGDILIFLPGEREIRDAAEILR 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 777 REvdglgpDVGELRCIPLYSTLPPNLQQRIFDPpppkrangAIGRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPR 856
Cdd:TIGR01967 301 KR------NLRHTEILPLYARLSNKEQQRVFQP--------HSGRRIVLATNVAETSLTVPGIHYVIDTGTARISRYSYR 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 857 IRVESLLVTAISKASAQQRAGRAGRTKPGKCFRLYTEKAYaNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDP 936
Cdd:TIGR01967 367 TKVQRLPIEPISQASANQRKGRCGRVAPGICIRLYSEEDF-NSRPEFTDPEILRTNLASVILQMLALRLGDIAAFPFIEA 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 937 PVPQ---------------------------------------------------CF----------------VRPAEAK 949
Cdd:TIGR01967 446 PDPRairdgfrlleelgaldddeaepqltpigrqlaqlpvdprlarmlleahrlgCLqevliiasalsiqdprERPMEKQ 525
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 950 KSADEAKMRFAHIDGDHLTMLNVYHAFKQNHED------PQWCYDNFINFRSLKSADNVRVQLSRIMDRFSLRRSSTDFS 1023
Cdd:TIGR01967 526 QAADQAHARFKDPRSDFLSRVNLWRHIEEQRQAlsanqfRNACRKQYLNYLRVREWQDIYRQLTQVVKELGLKLNEEPAD 605
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 1024 srdyYLNIRKALVSGFFMQVAHLERTGHYLTVKdNQVVQLHPSTVLDHK-PEWVLYNEFVLTTKNYIRTVTEVKPDWLIR 1102
Cdd:TIGR01967 606 ----YDAIHKALLSGLLSQIGMKDEKHEYDGAR-GRKFHIFPGSPLFKKpPKWVMAAELVETSKLYARLVAKIEPEWVEP 680
|
650
....*....|....*....
gi 1892353677 1103 VAPQYYDMSNF-PDCEARR 1120
Cdd:TIGR01967 681 VAGHLIKKNYFePHWEKKR 699
|
|
| PRK11131 |
PRK11131 |
ATP-dependent RNA helicase HrpA; Provisional |
543-1100 |
9.75e-122 |
|
ATP-dependent RNA helicase HrpA; Provisional
Pssm-ID: 182986 [Multi-domain] Cd Length: 1294 Bit Score: 406.37 E-value: 9.75e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEwiTGRyPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 622
Cdd:PRK11131 73 LPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICLE--LGR-GVKGLIGHTQPRRLAARTVANRIAEELETELGGC 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 623 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 702
Cdd:PRK11131 150 VGYKVRFNDQVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFILGYLKELLPRRPDLKVIITSATID 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 703 AGKFQEYFSKAPLMTVPGRTHPVEIFYTP------EPERDYLEAAIRTVIQihMCEEVEGDILLFLTGQEEIEEACKRIQ 776
Cdd:PRK11131 230 PERFSRHFNNAPIIEVSGRTYPVEVRYRPiveeadDTERDQLQAIFDAVDE--LGREGPGDILIFMSGEREIRDTADALN 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 777 REvdglgpDVGELRCIPLYSTLPPNLQQRIFDPpppkrangAIGRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPR 856
Cdd:PRK11131 308 KL------NLRHTEILPLYARLSNSEQNRVFQS--------HSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYR 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 857 IRVESLLVTAISKASAQQRAGRAGRTKPGKCFRLYTEKAYAN--EMQDntyPEILRSNLGTVVLQLKKLGIDDLVHFDFM 934
Cdd:PRK11131 374 TKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDDFLSrpEFTD---PEILRTNLASVILQMTALGLGDIAAFPFV 450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 935 DPP---------------------------------------------------------VPQCFV------------RP 945
Cdd:PRK11131 451 EAPdkrniqdgvrlleelgaittdeqasaykltplgrqlaqlpvdprlarmvleaqkhgcVREVMIitsalsiqdpreRP 530
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 946 AEAKKSADEAKMRFAHIDGDHLTMLNVYHAFKQNHED------PQWCYDNFINFRSLKSADNVRVQLSRIMDRFSLRRSS 1019
Cdd:PRK11131 531 MDKQQASDEKHRRFADKESDFLAFVNLWNYLQEQQKAlssnqfRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNS 610
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 1020 TDFSsrdyYLNIRKALVSGFFMQVAHLERTGHYLTVKDNQVVQLHPSTVLDHK-PEWVLYNEFVLTTKNYIRTVTEVKPD 1098
Cdd:PRK11131 611 EPAE----YREIHTALLTGLLSHIGMKDAEKQEYTGARNARFSIFPGSGLFKKpPKWVMVAELVETSRLWGRIAARIEPE 686
|
..
gi 1892353677 1099 WL 1100
Cdd:PRK11131 687 WI 688
|
|
| DEXHc_DHX15 |
cd17973 |
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA ... |
56-242 |
2.94e-114 |
|
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. DHX15 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438709 [Multi-domain] Cd Length: 187 Bit Score: 352.49 E-value: 2.94e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 56 RYFELFRKRIRLPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyPTKKAVACTQPRRVAAMSVAQRV 135
Cdd:cd17973 2 RYFEILEKRRELPVWEQKEDFLKLLKNNQILVLVGETGSGKTTQIPQFVLDDELPH-QPKKLVACTQPRRVAAMSVAQRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 136 SEEMDVELGQEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMD 215
Cdd:cd17973 81 AEEMDVKLGEEVGYSIRFEDCSSAKTILKYMTDGMLLREAMSDPLLSRYSVIILDEAHERTLATDILMGLLKEVVRRRPD 160
|
170 180
....*....|....*....|....*..
gi 1892353677 216 LKIVVMSATLDAGKFQEYFSKAPLMTV 242
Cdd:cd17973 161 LKLIVMSATLDAGKFQKYFDNAPLLKV 187
|
|
| DEXHc_DHX15 |
cd17973 |
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA ... |
532-718 |
2.94e-114 |
|
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. DHX15 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438709 [Multi-domain] Cd Length: 187 Bit Score: 352.49 E-value: 2.94e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 532 RYFELFRKRIRLPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyPTKKAVACTQPRRVAAMSVAQRV 611
Cdd:cd17973 2 RYFEILEKRRELPVWEQKEDFLKLLKNNQILVLVGETGSGKTTQIPQFVLDDELPH-QPKKLVACTQPRRVAAMSVAQRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 612 SEEMDVELGQEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMD 691
Cdd:cd17973 81 AEEMDVKLGEEVGYSIRFEDCSSAKTILKYMTDGMLLREAMSDPLLSRYSVIILDEAHERTLATDILMGLLKEVVRRRPD 160
|
170 180
....*....|....*....|....*..
gi 1892353677 692 LKIVVMSATLDAGKFQEYFSKAPLMTV 718
Cdd:cd17973 161 LKLIVMSATLDAGKFQKYFDNAPLLKV 187
|
|
| DEAH_box_HrpB |
TIGR01970 |
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but ... |
86-524 |
5.85e-105 |
|
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273901 [Multi-domain] Cd Length: 819 Bit Score: 349.45 E-value: 5.85e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 86 TVLVGETGSGKTTQIPQWCLEW--ITGRyptkkaVACTQPRRVAAMSVAQRVSEEMDVELGQEVGYSIRFEDCTSSRTLM 163
Cdd:TIGR01970 20 VVLEAPPGAGKSTAVPLALLDApgIGGK------IIMLEPRRLAARSAAQRLASQLGEAVGQTVGYRVRGENKVSRRTRL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 164 KYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQ-RMDLKIVVMSATLDAGKFQEYFSKAPLMTV 242
Cdd:TIGR01970 94 EVVTEGILTRMIQDDPELDGVGALIFDEFHERSLDADLGLALALDVQSSlREDLKILAMSATLDGERLSSLLPDAPVVES 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 243 PGRTHPVEIFYTPEPERDYLEAAIRTVIQiHMCEEVEGDILLFLTGQEEIEEACKRIQrevDGLGPDVgeLRCiPLYSTL 322
Cdd:TIGR01970 174 EGRSFPVEIRYLPLRGDQRLEDAVSRAVE-HALASETGSILVFLPGQAEIRRVQEQLA---ERLDSDV--LIC-PLYGEL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 323 PPNLQQRIFDPPPPKRangaigRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGR 402
Cdd:TIGR01970 247 SLAAQDRAIKPDPQGR------RKVVLATNIAETSLTIEGIRVVIDSGLARVARFDPKTGITRLETVRISQASATQRAGR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 403 AGRTKPGKCFRLYTEkAYANEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALDDD 482
Cdd:TIGR01970 321 AGRLEPGVCYRLWSE-EQHQRLPAQDEPEILQADLSGLALELAQWGAKDPSDLRWLDAPPSVALAAARQLLQRLGALDAQ 399
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1892353677 483 GNLTDLGSMMAEFPLDPQLAKMVMASCDFNCSNEVLSITAML 524
Cdd:TIGR01970 400 GRLTAHGKAMAALGCHPRLAAMLLSAHSTGLAALACDLAALL 441
|
|
| DEAH_box_HrpB |
TIGR01970 |
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but ... |
562-964 |
8.33e-93 |
|
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273901 [Multi-domain] Cd Length: 819 Bit Score: 315.94 E-value: 8.33e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 562 TVLVGETGSGKTTQIPQWCLEW--ITGRyptkkaVACTQPRRVAAMSVAQRVSEEMDVELGQEVGYSIRFEDCTSSRTLM 639
Cdd:TIGR01970 20 VVLEAPPGAGKSTAVPLALLDApgIGGK------IIMLEPRRLAARSAAQRLASQLGEAVGQTVGYRVRGENKVSRRTRL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 640 KYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQ-RMDLKIVVMSATLDAGKFQEYFSKAPLMTV 718
Cdd:TIGR01970 94 EVVTEGILTRMIQDDPELDGVGALIFDEFHERSLDADLGLALALDVQSSlREDLKILAMSATLDGERLSSLLPDAPVVES 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 719 PGRTHPVEIFYTPEPERDYLEAAIRTVIQiHMCEEVEGDILLFLTGQEEIEEACKRIQrevDGLGPDVgeLRCiPLYSTL 798
Cdd:TIGR01970 174 EGRSFPVEIRYLPLRGDQRLEDAVSRAVE-HALASETGSILVFLPGQAEIRRVQEQLA---ERLDSDV--LIC-PLYGEL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 799 PPNLQQRIFDPPPPKRangaigRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGR 878
Cdd:TIGR01970 247 SLAAQDRAIKPDPQGR------RKVVLATNIAETSLTIEGIRVVIDSGLARVARFDPKTGITRLETVRISQASATQRAGR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 879 AGRTKPGKCFRLYTEkAYANEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPvpqcfvrPAEAKKSADEAKMR 958
Cdd:TIGR01970 321 AGRLEPGVCYRLWSE-EQHQRLPAQDEPEILQADLSGLALELAQWGAKDPSDLRWLDAP-------PSVALAAARQLLQR 392
|
....*.
gi 1892353677 959 FAHIDG 964
Cdd:TIGR01970 393 LGALDA 398
|
|
| DEXHc_RHA-like |
cd17917 |
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) ... |
83-242 |
1.55e-86 |
|
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438707 [Multi-domain] Cd Length: 159 Bit Score: 276.65 E-value: 1.55e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 83 NQVTVLVGETGSGKTTQIPQWCLEWITGRyPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQEVGYSIRFEDCTSSRTL 162
Cdd:cd17917 1 NQVVVIVGETGSGKTTQVPQFLLEDGLAK-GGKGRIVCTQPRRIAAISVAERVAEERGEKLGEEVGYQIRFESKTSSKTR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 163 MKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLDAGKFQEYFSKAPLMTV 242
Cdd:cd17917 80 IKFCTDGILLRELLSDPLLSGYSHVILDEAHERSLDTDFLLGLLKDLLRKRPDLKVILMSATLDAEKFSSYFGGAPVIHI 159
|
|
| DEXHc_RHA-like |
cd17917 |
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) ... |
559-718 |
1.55e-86 |
|
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438707 [Multi-domain] Cd Length: 159 Bit Score: 276.65 E-value: 1.55e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 559 NQVTVLVGETGSGKTTQIPQWCLEWITGRyPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQEVGYSIRFEDCTSSRTL 638
Cdd:cd17917 1 NQVVVIVGETGSGKTTQVPQFLLEDGLAK-GGKGRIVCTQPRRIAAISVAERVAEERGEKLGEEVGYQIRFESKTSSKTR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 639 MKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLDAGKFQEYFSKAPLMTV 718
Cdd:cd17917 80 IKFCTDGILLRELLSDPLLSGYSHVILDEAHERSLDTDFLLGLLKDLLRKRPDLKVILMSATLDAEKFSSYFGGAPVIHI 159
|
|
| PRK11664 |
PRK11664 |
ATP-dependent RNA helicase HrpB; Provisional |
92-524 |
1.23e-84 |
|
ATP-dependent RNA helicase HrpB; Provisional
Pssm-ID: 236950 [Multi-domain] Cd Length: 812 Bit Score: 292.98 E-value: 1.23e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 92 TGSGKTTQIPQWCLEW--ITGRyptkkaVACTQPRRVAAMSVAQRVSEEMDVELGQEVGYSIRFEDCTSSRTLMKYMTDG 169
Cdd:PRK11664 29 TGAGKSTWLPLQLLQHggINGK------IIMLEPRRLAARNVAQRLAEQLGEKPGETVGYRMRAESKVGPNTRLEVVTEG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 170 MLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIikQ---RMDLKIVVMSATLDAGKFQEYFSKAPLMTVPGRT 246
Cdd:PRK11664 103 ILTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDV--QqglRDDLKLLIMSATLDNDRLQQLLPDAPVIVSEGRS 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 247 HPVEIFYTPEPERDYLEAAIRTVIQiHMCEEVEGDILLFLTGQEEIeeacKRIQREVDG-LGPDVgeLRCiPLYSTLPPN 325
Cdd:PRK11664 181 FPVERRYQPLPAHQRFDEAVARATA-ELLRQESGSLLLFLPGVGEI----QRVQEQLASrVASDV--LLC-PLYGALSLA 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 326 LQQRIFDPPPPKRangaigRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGR 405
Cdd:PRK11664 253 EQQKAILPAPAGR------RKVVLATNIAETSLTIEGIRLVVDSGLERVARFDPKTGLTRLVTQRISQASMTQRAGRAGR 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 406 TKPGKCFRLYTEKAYANEMQDNTyPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALDDDGNL 485
Cdd:PRK11664 327 LEPGICLHLYSKEQAERAAAQSE-PEILHSDLSGLLLELLQWGCHDPAQLSWLDQPPAAALAAAKRLLQQLGALDGQGRL 405
|
410 420 430
....*....|....*....|....*....|....*....
gi 1892353677 486 TDLGSMMAEFPLDPQLAKMVMASCDFncSNEVLSITAML 524
Cdd:PRK11664 406 TARGRKMAALGNDPRLAAMLVAAKED--DEAALATAAKL 442
|
|
| SF2_C_RHA |
cd18791 |
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ... |
247-415 |
8.18e-80 |
|
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350178 [Multi-domain] Cd Length: 171 Bit Score: 258.62 E-value: 8.18e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 247 HPVEIFYTPEP-----------ERDYLEAAIRTVIQIHMCEEvEGDILLFLTGQEEIEEACKRIQREVdgLGPDVGELRC 315
Cdd:cd18791 1 FPVEVYYLEDIlellgissekeDPDYVDAAVRLILQIHRTEE-PGDILVFLPGQEEIERLCELLREEL--LSPDLGKLLV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 316 IPLYSTLPPNLQQRIFDPPPPKRangaigRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKAS 395
Cdd:cd18791 78 LPLHSSLPPEEQQRVFEPPPPGV------RKVVLATNIAETSITIPGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISKAS 151
|
170 180
....*....|....*....|
gi 1892353677 396 AQQRAGRAGRTKPGKCFRLY 415
Cdd:cd18791 152 AEQRAGRAGRTRPGKCYRLY 171
|
|
| SF2_C_RHA |
cd18791 |
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ... |
723-891 |
8.18e-80 |
|
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350178 [Multi-domain] Cd Length: 171 Bit Score: 258.62 E-value: 8.18e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 723 HPVEIFYTPEP-----------ERDYLEAAIRTVIQIHMCEEvEGDILLFLTGQEEIEEACKRIQREVdgLGPDVGELRC 791
Cdd:cd18791 1 FPVEVYYLEDIlellgissekeDPDYVDAAVRLILQIHRTEE-PGDILVFLPGQEEIERLCELLREEL--LSPDLGKLLV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 792 IPLYSTLPPNLQQRIFDPPPPKRangaigRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKAS 871
Cdd:cd18791 78 LPLHSSLPPEEQQRVFEPPPPGV------RKVVLATNIAETSITIPGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISKAS 151
|
170 180
....*....|....*....|
gi 1892353677 872 AQQRAGRAGRTKPGKCFRLY 891
Cdd:cd18791 152 AEQRAGRAGRTRPGKCYRLY 171
|
|
| DEXHc_DHX16 |
cd17974 |
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably ... |
67-242 |
3.25e-79 |
|
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably involved in pre-mRNA splicing. DHX16 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350732 [Multi-domain] Cd Length: 174 Bit Score: 257.05 E-value: 3.25e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEwiTGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 146
Cdd:cd17974 1 LPVYPYRDDLLAAVKEHQVLIIVGETGSGKTTQIPQYLHE--AGYTKGGGKIGCTQPRRVAAMSVAARVAEEMGVKLGNE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 147 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 226
Cdd:cd17974 79 VGYSIRFEDCTSEKTVLKYMTDGMLLREFLTEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPDLKLLISSATMD 158
|
170
....*....|....*.
gi 1892353677 227 AGKFQEYFSKAPLMTV 242
Cdd:cd17974 159 AEKFSAFFDDAPIFRI 174
|
|
| DEXHc_DHX16 |
cd17974 |
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably ... |
543-718 |
3.25e-79 |
|
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably involved in pre-mRNA splicing. DHX16 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350732 [Multi-domain] Cd Length: 174 Bit Score: 257.05 E-value: 3.25e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEwiTGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 622
Cdd:cd17974 1 LPVYPYRDDLLAAVKEHQVLIIVGETGSGKTTQIPQYLHE--AGYTKGGGKIGCTQPRRVAAMSVAARVAEEMGVKLGNE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 623 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 702
Cdd:cd17974 79 VGYSIRFEDCTSEKTVLKYMTDGMLLREFLTEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPDLKLLISSATMD 158
|
170
....*....|....*.
gi 1892353677 703 AGKFQEYFSKAPLMTV 718
Cdd:cd17974 159 AEKFSAFFDDAPIFRI 174
|
|
| DEXHc_DHX8 |
cd17971 |
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as ... |
539-719 |
3.61e-79 |
|
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22) acts late in the splicing of pre-mRNA and mediates the release of the spliced mRNA from spliceosomes. DHX8 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350729 [Multi-domain] Cd Length: 179 Bit Score: 257.03 E-value: 3.61e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 539 KRIRLPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEwitGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVE 618
Cdd:cd17971 2 QRESLPIYKLKEQLIQAVHDNQILVVIGETGSGKTTQITQYLAE---AGYTSRGKIGCTQPRRVAAMSVAKRVAEEFGCC 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 619 LGQEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMS 698
Cdd:cd17971 79 LGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLSQYSVIMLDEAHERTIHTDVLFGLLKKTVQKRPDLKLIVTS 158
|
170 180
....*....|....*....|.
gi 1892353677 699 ATLDAGKFQEYFSKAPLMTVP 719
Cdd:cd17971 159 ATLDAVKFSQYFYEAPIFTIP 179
|
|
| DEXHc_DHX8 |
cd17971 |
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as ... |
63-243 |
3.61e-79 |
|
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22) acts late in the splicing of pre-mRNA and mediates the release of the spliced mRNA from spliceosomes. DHX8 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350729 [Multi-domain] Cd Length: 179 Bit Score: 257.03 E-value: 3.61e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 63 KRIRLPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEwitGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVE 142
Cdd:cd17971 2 QRESLPIYKLKEQLIQAVHDNQILVVIGETGSGKTTQITQYLAE---AGYTSRGKIGCTQPRRVAAMSVAKRVAEEFGCC 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 143 LGQEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMS 222
Cdd:cd17971 79 LGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLSQYSVIMLDEAHERTIHTDVLFGLLKKTVQKRPDLKLIVTS 158
|
170 180
....*....|....*....|.
gi 1892353677 223 ATLDAGKFQEYFSKAPLMTVP 243
Cdd:cd17971 159 ATLDAVKFSQYFYEAPIFTIP 179
|
|
| DEXHc_DHX33 |
cd17978 |
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA ... |
67-240 |
7.99e-76 |
|
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA polymerase I transcription of the 47S precursor rRNA. DHX33 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438710 [Multi-domain] Cd Length: 178 Bit Score: 247.65 E-value: 7.99e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyptKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 146
Cdd:cd17978 1 LPIYSARKRLLEELRKHDTVIIIGETGSGKTTQIPQYLYEAGFAR---GGMIGITQPRRVAAVSVAKRVAEEMGVELGQL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 147 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMD-----LKIVVM 221
Cdd:cd17978 78 VGYSVRFDDVTSEETRIKYMTDGMLLREAIGDPLLSKYSVIILDEAHERTVHTDVLFGLVKSAQRRRKEqklspLKVIIM 157
|
170
....*....|....*....
gi 1892353677 222 SATLDAGKFQEYFSKAPLM 240
Cdd:cd17978 158 SATLDADLFSEYFNGAPVL 176
|
|
| DEXHc_DHX33 |
cd17978 |
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA ... |
543-716 |
7.99e-76 |
|
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA polymerase I transcription of the 47S precursor rRNA. DHX33 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438710 [Multi-domain] Cd Length: 178 Bit Score: 247.65 E-value: 7.99e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyptKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 622
Cdd:cd17978 1 LPIYSARKRLLEELRKHDTVIIIGETGSGKTTQIPQYLYEAGFAR---GGMIGITQPRRVAAVSVAKRVAEEMGVELGQL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 623 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMD-----LKIVVM 697
Cdd:cd17978 78 VGYSVRFDDVTSEETRIKYMTDGMLLREAIGDPLLSKYSVIILDEAHERTVHTDVLFGLVKSAQRRRKEqklspLKVIIM 157
|
170
....*....|....*....
gi 1892353677 698 SATLDAGKFQEYFSKAPLM 716
Cdd:cd17978 158 SATLDADLFSEYFNGAPVL 176
|
|
| DEXHc_DHX38 |
cd17983 |
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as ... |
67-242 |
1.42e-75 |
|
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as PRP16) is involved in pre-mRNA splicing. DHX38 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350741 [Multi-domain] Cd Length: 173 Bit Score: 246.99 E-value: 1.42e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEwitGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 146
Cdd:cd17983 1 LPIFAVRQELLNVIRDNNVVIVVGETGSGKTTQLTQYLHE---DGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGVELGEE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 147 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 226
Cdd:cd17983 78 VGYAIRFEDCTSENTVIKYMTDGILLRESLRDPDLDKYSAIIMDEAHERSLNTDVLFGLLREVVARRRDLKLIVTSATMD 157
|
170
....*....|....*.
gi 1892353677 227 AGKFQEYFSKAPLMTV 242
Cdd:cd17983 158 ADKFADFFGNVPIFTI 173
|
|
| DEXHc_DHX38 |
cd17983 |
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as ... |
543-718 |
1.42e-75 |
|
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as PRP16) is involved in pre-mRNA splicing. DHX38 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350741 [Multi-domain] Cd Length: 173 Bit Score: 246.99 E-value: 1.42e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEwitGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 622
Cdd:cd17983 1 LPIFAVRQELLNVIRDNNVVIVVGETGSGKTTQLTQYLHE---DGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGVELGEE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 623 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 702
Cdd:cd17983 78 VGYAIRFEDCTSENTVIKYMTDGILLRESLRDPDLDKYSAIIMDEAHERSLNTDVLFGLLREVVARRRDLKLIVTSATMD 157
|
170
....*....|....*.
gi 1892353677 703 AGKFQEYFSKAPLMTV 718
Cdd:cd17983 158 ADKFADFFGNVPIFTI 173
|
|
| PRK11664 |
PRK11664 |
ATP-dependent RNA helicase HrpB; Provisional |
568-937 |
9.14e-72 |
|
ATP-dependent RNA helicase HrpB; Provisional
Pssm-ID: 236950 [Multi-domain] Cd Length: 812 Bit Score: 256.39 E-value: 9.14e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 568 TGSGKTTQIPQWCLEW--ITGRyptkkaVACTQPRRVAAMSVAQRVSEEMDVELGQEVGYSIRFEDCTSSRTLMKYMTDG 645
Cdd:PRK11664 29 TGAGKSTWLPLQLLQHggINGK------IIMLEPRRLAARNVAQRLAEQLGEKPGETVGYRMRAESKVGPNTRLEVVTEG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 646 MLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIikQ---RMDLKIVVMSATLDAGKFQEYFSKAPLMTVPGRT 722
Cdd:PRK11664 103 ILTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDV--QqglRDDLKLLIMSATLDNDRLQQLLPDAPVIVSEGRS 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 723 HPVEIFYTPEPERDYLEAAIRTVIQiHMCEEVEGDILLFLTGQEEIeeacKRIQREVDG-LGPDVgeLRCiPLYSTLPPN 801
Cdd:PRK11664 181 FPVERRYQPLPAHQRFDEAVARATA-ELLRQESGSLLLFLPGVGEI----QRVQEQLASrVASDV--LLC-PLYGALSLA 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 802 LQQRIFDPPPPKRangaigRKIVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGR 881
Cdd:PRK11664 253 EQQKAILPAPAGR------RKVVLATNIAETSLTIEGIRLVVDSGLERVARFDPKTGLTRLVTQRISQASMTQRAGRAGR 326
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1892353677 882 TKPGKCFRLYTEKAYANEMQDNTyPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPP 937
Cdd:PRK11664 327 LEPGICLHLYSKEQAERAAAQSE-PEILHSDLSGLLLELLQWGCHDPAQLSWLDQP 381
|
|
| DEXHc_DHX35 |
cd17980 |
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and ... |
67-234 |
2.18e-68 |
|
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and seems to be associated with risk to thyroid cancers. It also has been shown to positively regulate poxviruses, such as Myxoma virus. DEAH-box helicase 35 (DHX35) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350738 [Multi-domain] Cd Length: 185 Bit Score: 227.35 E-value: 2.18e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE--WITGryptKKAVACTQPRRVAAMSVAQRVSEEMDVELG 144
Cdd:cd17980 1 LPVFKLRNHILYLVENYQTIVIVGETGCGKSTQIPQYLAEagWTAG----GRVVGCTQPRRVAAVTVAGRVAEEMGAVLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 145 QEVGYSIRFEDCTSS-RTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSA 223
Cdd:cd17980 77 HEVGYCIRFDDCTDPqATRIKFLTDGMLVREMMLDPLLTKYSVIMLDEAHERTLYTDILIGLLKKIQKKRGDLRLIVASA 156
|
170
....*....|.
gi 1892353677 224 TLDAGKFQEYF 234
Cdd:cd17980 157 TLDAEKFRDFF 167
|
|
| DEXHc_DHX35 |
cd17980 |
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and ... |
543-710 |
2.18e-68 |
|
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and seems to be associated with risk to thyroid cancers. It also has been shown to positively regulate poxviruses, such as Myxoma virus. DEAH-box helicase 35 (DHX35) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350738 [Multi-domain] Cd Length: 185 Bit Score: 227.35 E-value: 2.18e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE--WITGryptKKAVACTQPRRVAAMSVAQRVSEEMDVELG 620
Cdd:cd17980 1 LPVFKLRNHILYLVENYQTIVIVGETGCGKSTQIPQYLAEagWTAG----GRVVGCTQPRRVAAVTVAGRVAEEMGAVLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 621 QEVGYSIRFEDCTSS-RTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSA 699
Cdd:cd17980 77 HEVGYCIRFDDCTDPqATRIKFLTDGMLVREMMLDPLLTKYSVIMLDEAHERTLYTDILIGLLKKIQKKRGDLRLIVASA 156
|
170
....*....|.
gi 1892353677 700 TLDAGKFQEYF 710
Cdd:cd17980 157 TLDAEKFRDFF 167
|
|
| DEXHc_DHX40 |
cd17984 |
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the ... |
543-718 |
2.87e-60 |
|
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350742 [Multi-domain] Cd Length: 178 Bit Score: 203.93 E-value: 2.87e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRYptkKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 622
Cdd:cd17984 1 LPIQKQRKKLVQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQH---GMIGVTQPRRVAAISVAQRVAEEMKCTLGSK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 623 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQR-----MDLKIVVM 697
Cdd:cd17984 78 VGYQVRFDDCSSKETAIKYMTDGCLLRHILADPNLTKYSVIILDEAHERSLTTDILFGLLKKLFQEKspnrkEHLKVVVM 157
|
170 180
....*....|....*....|.
gi 1892353677 698 SATLDAGKFQEYFSKAPLMTV 718
Cdd:cd17984 158 SATLELAKLSAFFGNCPVFDI 178
|
|
| DEXHc_DHX40 |
cd17984 |
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the ... |
67-242 |
2.87e-60 |
|
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350742 [Multi-domain] Cd Length: 178 Bit Score: 203.93 E-value: 2.87e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRYptkKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 146
Cdd:cd17984 1 LPIQKQRKKLVQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQH---GMIGVTQPRRVAAISVAQRVAEEMKCTLGSK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 147 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQR-----MDLKIVVM 221
Cdd:cd17984 78 VGYQVRFDDCSSKETAIKYMTDGCLLRHILADPNLTKYSVIILDEAHERSLTTDILFGLLKKLFQEKspnrkEHLKVVVM 157
|
170 180
....*....|....*....|.
gi 1892353677 222 SATLDAGKFQEYFSKAPLMTV 242
Cdd:cd17984 158 SATLELAKLSAFFGNCPVFDI 178
|
|
| DEXHc_HrpA |
cd17989 |
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA ... |
67-242 |
3.77e-60 |
|
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350747 [Multi-domain] Cd Length: 173 Bit Score: 203.46 E-value: 3.77e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyptKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 146
Cdd:cd17989 1 LPVSQKRDEIAKAIAENQVVIIAGETGSGKTTQLPKICLELGRGI---RGLIGHTQPRRLAARSVAERIAEELKTELGGA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 147 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 226
Cdd:cd17989 78 VGYKVRFTDQTSDETCVKLMTDGILLAETQTDRYLRAYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATID 157
|
170
....*....|....*.
gi 1892353677 227 AGKFQEYFSKAPLMTV 242
Cdd:cd17989 158 AERFSRHFNNAPIIEV 173
|
|
| DEXHc_HrpA |
cd17989 |
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA ... |
543-718 |
3.77e-60 |
|
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350747 [Multi-domain] Cd Length: 173 Bit Score: 203.46 E-value: 3.77e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyptKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 622
Cdd:cd17989 1 LPVSQKRDEIAKAIAENQVVIIAGETGSGKTTQLPKICLELGRGI---RGLIGHTQPRRLAARSVAERIAEELKTELGGA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 623 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 702
Cdd:cd17989 78 VGYKVRFTDQTSDETCVKLMTDGILLAETQTDRYLRAYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATID 157
|
170
....*....|....*.
gi 1892353677 703 AGKFQEYFSKAPLMTV 718
Cdd:cd17989 158 AERFSRHFNNAPIIEV 173
|
|
| DEXHc_DHX32 |
cd17977 |
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the ... |
67-242 |
4.43e-60 |
|
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350735 [Multi-domain] Cd Length: 176 Bit Score: 203.52 E-value: 4.43e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 146
Cdd:cd17977 1 LPVWEAKYEFMESLAHNQIVIVSGDAKTGKSSQIPQWCAEYCLSAHYQHGVVVCTQVHKQTAVWLALRVADEMDVNIGHE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 147 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 226
Cdd:cd17977 81 VGYVIPFENCCTNETILRYCTDDMLLREMMSDPLLESYGVIILDDAHERTVSTDVLLGLLKDVLLSRPELKLVIITCPHL 160
|
170
....*....|....*.
gi 1892353677 227 AGKFQEYFSKAPLMTV 242
Cdd:cd17977 161 SSKLLSYYGNVPLIEV 176
|
|
| DEXHc_DHX32 |
cd17977 |
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the ... |
543-718 |
4.43e-60 |
|
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350735 [Multi-domain] Cd Length: 176 Bit Score: 203.52 E-value: 4.43e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQE 622
Cdd:cd17977 1 LPVWEAKYEFMESLAHNQIVIVSGDAKTGKSSQIPQWCAEYCLSAHYQHGVVVCTQVHKQTAVWLALRVADEMDVNIGHE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 623 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 702
Cdd:cd17977 81 VGYVIPFENCCTNETILRYCTDDMLLREMMSDPLLESYGVIILDDAHERTVSTDVLLGLLKDVLLSRPELKLVIITCPHL 160
|
170
....*....|....*.
gi 1892353677 703 AGKFQEYFSKAPLMTV 718
Cdd:cd17977 161 SSKLLSYYGNVPLIEV 176
|
|
| DEXHc_DHX37 |
cd17982 |
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ... |
67-238 |
2.26e-53 |
|
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350740 [Multi-domain] Cd Length: 191 Bit Score: 184.87 E-value: 2.26e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE--WITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVeLG 144
Cdd:cd17982 1 LPILAEEQEIMEAINENPVVIICGETGSGKTTQVPQFLYEagFGSPESDNPGMIGITQPRRVAAVSMAKRVAEELNV-FG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 145 QEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMD--------- 215
Cdd:cd17982 80 KEVSYQIRYDSTVSENTKIKFMTDGVLLKEIQTDFLLRKYSVIIIDEAHERSVNTDILIGMLSRIVPLRAKlylqdqtvk 159
|
170 180
....*....|....*....|....*..
gi 1892353677 216 -LKIVVMSATLDAGKFQE---YFSKAP 238
Cdd:cd17982 160 pLKLVIMSATLRVEDFTEnklLFPRPP 186
|
|
| DEXHc_DHX37 |
cd17982 |
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ... |
543-714 |
2.26e-53 |
|
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350740 [Multi-domain] Cd Length: 191 Bit Score: 184.87 E-value: 2.26e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE--WITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVeLG 620
Cdd:cd17982 1 LPILAEEQEIMEAINENPVVIICGETGSGKTTQVPQFLYEagFGSPESDNPGMIGITQPRRVAAVSMAKRVAEELNV-FG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 621 QEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMD--------- 691
Cdd:cd17982 80 KEVSYQIRYDSTVSENTKIKFMTDGVLLKEIQTDFLLRKYSVIIIDEAHERSVNTDILIGMLSRIVPLRAKlylqdqtvk 159
|
170 180
....*....|....*....|....*..
gi 1892353677 692 -LKIVVMSATLDAGKFQE---YFSKAP 714
Cdd:cd17982 160 pLKLVIMSATLRVEDFTEnklLFPRPP 186
|
|
| DEXQc_DQX1 |
cd17986 |
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 ... |
67-242 |
1.70e-52 |
|
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 (DQX1) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350744 [Multi-domain] Cd Length: 177 Bit Score: 182.02 E-value: 1.70e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLV-GETGSGKTTQIPQWCLEWITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQ 145
Cdd:cd17986 1 LPIWAAKFTFLEQLESPSGIVLVsGEPGSGKSTQVPQWCAEFALSRGFQKGQVTVTQPHPLAARSLALRVADEMDLNLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 146 EVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATL 225
Cdd:cd17986 81 EVGYSIPQEDCTGPNTILRFCWDRLLLQEMTSTPLLGAWGVVVLDEAQERSVASDSLLGLLKDVRLQRPELRVVVVTSPA 160
|
170
....*....|....*..
gi 1892353677 226 DAGKFQEYFSKAPLMTV 242
Cdd:cd17986 161 LEPKLRAFWGNPPVVHV 177
|
|
| DEXQc_DQX1 |
cd17986 |
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 ... |
543-718 |
1.70e-52 |
|
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 (DQX1) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350744 [Multi-domain] Cd Length: 177 Bit Score: 182.02 E-value: 1.70e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLV-GETGSGKTTQIPQWCLEWITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQ 621
Cdd:cd17986 1 LPIWAAKFTFLEQLESPSGIVLVsGEPGSGKSTQVPQWCAEFALSRGFQKGQVTVTQPHPLAARSLALRVADEMDLNLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 622 EVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATL 701
Cdd:cd17986 81 EVGYSIPQEDCTGPNTILRFCWDRLLLQEMTSTPLLGAWGVVVLDEAQERSVASDSLLGLLKDVRLQRPELRVVVVTSPA 160
|
170
....*....|....*..
gi 1892353677 702 DAGKFQEYFSKAPLMTV 718
Cdd:cd17986 161 LEPKLRAFWGNPPVVHV 177
|
|
| DEXHc_DHX34 |
cd17979 |
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in ... |
543-718 |
2.16e-51 |
|
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in the nonsense-mediated decay (NMD), a surveillance mechanism that degrades aberrant mRNAs. DHX34 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350737 [Multi-domain] Cd Length: 170 Bit Score: 178.41 E-value: 2.16e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyptkkaVACTQPRRVAAMSVAQRVSEEMDVELGQE 622
Cdd:cd17979 1 LPIAQYREKIIELLKTHQVVIVAGDTGCGKSTQVPQYLLAAGFRH------IACTQPRRIACISLAKRVAFESLNQYGSK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 623 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 702
Cdd:cd17979 75 VAYQIRFERTRTLATKLLFLTEGLLLRQIQRDASLPQYNVLILDEVHERHLHGDFLLGVLRCLLRLRPDLKLILMSATIN 154
|
170
....*....|....*.
gi 1892353677 703 AGKFQEYFSKAPLMTV 718
Cdd:cd17979 155 IELFSGYFEGAPVVQV 170
|
|
| DEXHc_DHX34 |
cd17979 |
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in ... |
67-242 |
2.16e-51 |
|
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in the nonsense-mediated decay (NMD), a surveillance mechanism that degrades aberrant mRNAs. DHX34 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350737 [Multi-domain] Cd Length: 170 Bit Score: 178.41 E-value: 2.16e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyptkkaVACTQPRRVAAMSVAQRVSEEMDVELGQE 146
Cdd:cd17979 1 LPIAQYREKIIELLKTHQVVIVAGDTGCGKSTQVPQYLLAAGFRH------IACTQPRRIACISLAKRVAFESLNQYGSK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 147 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATLD 226
Cdd:cd17979 75 VAYQIRFERTRTLATKLLFLTEGLLLRQIQRDASLPQYNVLILDEVHERHLHGDFLLGVLRCLLRLRPDLKLILMSATIN 154
|
170
....*....|....*.
gi 1892353677 227 AGKFQEYFSKAPLMTV 242
Cdd:cd17979 155 IELFSGYFEGAPVVQV 170
|
|
| DEXHc_DHX36 |
cd17981 |
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as ... |
67-242 |
3.14e-49 |
|
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as G4-resolvase 1 or G4R1, MLE-like protein 1 and RNA helicase associated with AU-rich element or RHAU) unwinds a G4-quadruplex in human telomerase RNA. DHX36 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350739 [Multi-domain] Cd Length: 180 Bit Score: 172.72 E-value: 3.14e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE-WITGRYPTKKAVACTQPRRVAAMSVAQRVSEEM--DVEL 143
Cdd:cd17981 1 LPSYGMKQEIINMIDNNQVTVISGETGCGKTTQVTQFILDdAIERGKGSSCRIVCTQPRRISAISVAERVAAERaeSCGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 144 GQEVGYSIRFED-CTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMS 222
Cdd:cd17981 81 GNSTGYQIRLESrKPRKQGSILYCTTGIVLQWLQSDPHLSNVSHLVLDEIHERNLQSDVLMGIVKDLLPFRSDLKVILMS 160
|
170 180
....*....|....*....|
gi 1892353677 223 ATLDAGKFQEYFSKAPLMTV 242
Cdd:cd17981 161 ATLNAEKFSDYFNNCPMIHI 180
|
|
| DEXHc_DHX36 |
cd17981 |
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as ... |
543-718 |
3.14e-49 |
|
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as G4-resolvase 1 or G4R1, MLE-like protein 1 and RNA helicase associated with AU-rich element or RHAU) unwinds a G4-quadruplex in human telomerase RNA. DHX36 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350739 [Multi-domain] Cd Length: 180 Bit Score: 172.72 E-value: 3.14e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE-WITGRYPTKKAVACTQPRRVAAMSVAQRVSEEM--DVEL 619
Cdd:cd17981 1 LPSYGMKQEIINMIDNNQVTVISGETGCGKTTQVTQFILDdAIERGKGSSCRIVCTQPRRISAISVAERVAAERaeSCGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 620 GQEVGYSIRFED-CTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMS 698
Cdd:cd17981 81 GNSTGYQIRLESrKPRKQGSILYCTTGIVLQWLQSDPHLSNVSHLVLDEIHERNLQSDVLMGIVKDLLPFRSDLKVILMS 160
|
170 180
....*....|....*....|
gi 1892353677 699 ATLDAGKFQEYFSKAPLMTV 718
Cdd:cd17981 161 ATLNAEKFSDYFNNCPMIHI 180
|
|
| DEXHc_DHX57 |
cd17985 |
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the ... |
67-242 |
7.83e-49 |
|
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350743 [Multi-domain] Cd Length: 177 Bit Score: 171.18 E-value: 7.83e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRYPTKKA-VACTQPRRVAAMSVAQRVSEEMDVELGQ 145
Cdd:cd17985 1 LPAWQERETILELLEKHQVLVISGMTGCGKTTQIPQFILDNSLQGPPLPVAnIICTQPRRISAISVAERVAQERAERVGQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 146 EVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATL 225
Cdd:cd17985 81 SVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDPTLQGVTHVIVDEVHERTEESDFLLLVLKDLMVQRPDLKVILMSATL 160
|
170
....*....|....*..
gi 1892353677 226 DAGKFQEYFSKAPLMTV 242
Cdd:cd17985 161 NAELFSDYFNSCPVIHI 177
|
|
| DEXHc_DHX57 |
cd17985 |
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the ... |
543-718 |
7.83e-49 |
|
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350743 [Multi-domain] Cd Length: 177 Bit Score: 171.18 E-value: 7.83e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRYPTKKA-VACTQPRRVAAMSVAQRVSEEMDVELGQ 621
Cdd:cd17985 1 LPAWQERETILELLEKHQVLVISGMTGCGKTTQIPQFILDNSLQGPPLPVAnIICTQPRRISAISVAERVAQERAERVGQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 622 EVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSATL 701
Cdd:cd17985 81 SVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDPTLQGVTHVIVDEVHERTEESDFLLLVLKDLMVQRPDLKVILMSATL 160
|
170
....*....|....*..
gi 1892353677 702 DAGKFQEYFSKAPLMTV 718
Cdd:cd17985 161 NAELFSDYFNSCPVIHI 177
|
|
| DEXHc_DHX29 |
cd17975 |
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of ... |
67-242 |
2.98e-47 |
|
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of the 43S pre-initiation complex involved in translation initiation of mRNAs with structured 5'-UTRs. DHX29 is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350733 [Multi-domain] Cd Length: 183 Bit Score: 167.01 E-value: 2.98e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE--WITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELG 144
Cdd:cd17975 1 LPVFKHRESILETLKRHRVVVVAGETGSGKSTQVPQFLLEdlLLNGGTAQKCNIVCTQPRRISAMSLATRVCEELGCESG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 145 -----QEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIV 219
Cdd:cd17975 81 pggknSLCGYQIRMESRTGEATRLLYCTTGVLLRKLQEDGLLSSISHIIVDEVHERSVQSDFLLIILKEILHKRSDLHLI 160
|
170 180
....*....|....*....|...
gi 1892353677 220 VMSATLDAGKFQEYFSKAPLMTV 242
Cdd:cd17975 161 LMSATVDCEKFSSYFTHCPILRI 183
|
|
| DEXHc_DHX29 |
cd17975 |
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of ... |
543-718 |
2.98e-47 |
|
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of the 43S pre-initiation complex involved in translation initiation of mRNAs with structured 5'-UTRs. DHX29 is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350733 [Multi-domain] Cd Length: 183 Bit Score: 167.01 E-value: 2.98e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE--WITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELG 620
Cdd:cd17975 1 LPVFKHRESILETLKRHRVVVVAGETGSGKSTQVPQFLLEdlLLNGGTAQKCNIVCTQPRRISAMSLATRVCEELGCESG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 621 -----QEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIV 695
Cdd:cd17975 81 pggknSLCGYQIRMESRTGEATRLLYCTTGVLLRKLQEDGLLSSISHIIVDEVHERSVQSDFLLIILKEILHKRSDLHLI 160
|
170 180
....*....|....*....|...
gi 1892353677 696 VMSATLDAGKFQEYFSKAPLMTV 718
Cdd:cd17975 161 LMSATVDCEKFSSYFTHCPILRI 183
|
|
| DEXHc_YTHDC2 |
cd17987 |
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) ... |
67-242 |
8.03e-45 |
|
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) regulates mRNA translation and stability via binding to N6-methyladenosine, a modified RNA nucleotide enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. YTHDC2 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350745 [Multi-domain] Cd Length: 176 Bit Score: 160.00 E-value: 8.03e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE--WITGRyPTKkaVACTQPRRVAAMSVAQRVSEEMDVELG 144
Cdd:cd17987 1 LPVFEKQEQIVRIIKENKVVLIVGETGSGKTTQIPQFLLDdcYANGI-PCR--IFCTQPRRLAAIAVAERVAAERGEKIG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 145 QEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMS-DPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSA 223
Cdd:cd17987 78 QTVGYQIRLESRVSPKTLLTFCTNGVLLRTLMAgDSALSTVTHVIVDEVHERDRFSDFLLTKLRDILQKHPNLKLILSSA 157
|
170
....*....|....*....
gi 1892353677 224 TLDAGKFQEYFSKAPLMTV 242
Cdd:cd17987 158 ALDVNLFIRYFGSCPVIYI 176
|
|
| DEXHc_YTHDC2 |
cd17987 |
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) ... |
543-718 |
8.03e-45 |
|
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) regulates mRNA translation and stability via binding to N6-methyladenosine, a modified RNA nucleotide enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. YTHDC2 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350745 [Multi-domain] Cd Length: 176 Bit Score: 160.00 E-value: 8.03e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE--WITGRyPTKkaVACTQPRRVAAMSVAQRVSEEMDVELG 620
Cdd:cd17987 1 LPVFEKQEQIVRIIKENKVVLIVGETGSGKTTQIPQFLLDdcYANGI-PCR--IFCTQPRRLAAIAVAERVAAERGEKIG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 621 QEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMS-DPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSA 699
Cdd:cd17987 78 QTVGYQIRLESRVSPKTLLTFCTNGVLLRTLMAgDSALSTVTHVIVDEVHERDRFSDFLLTKLRDILQKHPNLKLILSSA 157
|
170
....*....|....*....
gi 1892353677 700 TLDAGKFQEYFSKAPLMTV 718
Cdd:cd17987 158 ALDVNLFIRYFGSCPVIYI 176
|
|
| DEXHc_DHX30 |
cd17976 |
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an ... |
543-718 |
1.66e-42 |
|
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an important role in the assembly of the mitochondrial large ribosomal subunit. DHX30 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350734 [Multi-domain] Cd Length: 178 Bit Score: 153.41 E-value: 1.66e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE-WITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQ 621
Cdd:cd17976 1 LPVDSHKESILSAIEQNPVVVISGDTGCGKTTRIPQFILEdYVLRGRGARCNVVITQPRRISAVSVAQRVAHELGPNLRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 622 EVGYSIRFEDCTSSRT-LMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSAT 700
Cdd:cd17976 81 NVGYQVRLESRPPPRGgALLFCTVGVLLKKLQSNPRLEGVSHVIVDEVHERDVNTDFLLILLKGVLQLNPELRVVLMSAT 160
|
170
....*....|....*...
gi 1892353677 701 LDAGKFQEYFSKAPLMTV 718
Cdd:cd17976 161 GDNQRLSRYFGGCPVVRV 178
|
|
| DEXHc_DHX30 |
cd17976 |
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an ... |
67-242 |
1.66e-42 |
|
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an important role in the assembly of the mitochondrial large ribosomal subunit. DHX30 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350734 [Multi-domain] Cd Length: 178 Bit Score: 153.41 E-value: 1.66e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLE-WITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVELGQ 145
Cdd:cd17976 1 LPVDSHKESILSAIEQNPVVVISGDTGCGKTTRIPQFILEdYVLRGRGARCNVVITQPRRISAVSVAQRVAHELGPNLRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 146 EVGYSIRFEDCTSSRT-LMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVMSAT 224
Cdd:cd17976 81 NVGYQVRLESRPPPRGgALLFCTVGVLLKKLQSNPRLEGVSHVIVDEVHERDVNTDFLLILLKGVLQLNPELRVVLMSAT 160
|
170
....*....|....*...
gi 1892353677 225 LDAGKFQEYFSKAPLMTV 242
Cdd:cd17976 161 GDNQRLSRYFGGCPVVRV 178
|
|
| DEXHc_HrpB |
cd17990 |
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ... |
67-239 |
7.10e-41 |
|
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438711 [Multi-domain] Cd Length: 174 Bit Score: 148.25 E-value: 7.10e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyPTKkaVACTQPRRVAAMSVAQRVSEEMDVELGQE 146
Cdd:cd17990 1 LPIAAVLPALRAALDAGGQVVLEAPPGAGKTTRVPLALLAELWIA-GGK--IIVLEPRRVAARAAARRLATLLGEAPGET 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 147 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEiIKQ--RMDLKIVVMSAT 224
Cdd:cd17990 78 VGYRVRGESRVGRRTRVEVVTEGVLLRRLQRDPELSGVGAVILDEFHERSLDADLALALLLE-VQQllRDDLRLLAMSAT 156
|
170
....*....|....*
gi 1892353677 225 LDAGKFQEYFSKAPL 239
Cdd:cd17990 157 LDGDGLAALLPEAPV 171
|
|
| DEXHc_HrpB |
cd17990 |
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ... |
543-715 |
7.10e-41 |
|
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438711 [Multi-domain] Cd Length: 174 Bit Score: 148.25 E-value: 7.10e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEWITGRyPTKkaVACTQPRRVAAMSVAQRVSEEMDVELGQE 622
Cdd:cd17990 1 LPIAAVLPALRAALDAGGQVVLEAPPGAGKTTRVPLALLAELWIA-GGK--IIVLEPRRVAARAAARRLATLLGEAPGET 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 623 VGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEiIKQ--RMDLKIVVMSAT 700
Cdd:cd17990 78 VGYRVRGESRVGRRTRVEVVTEGVLLRRLQRDPELSGVGAVILDEFHERSLDADLALALLLE-VQQllRDDLRLLAMSAT 156
|
170
....*....|....*
gi 1892353677 701 LDAGKFQEYFSKAPL 715
Cdd:cd17990 157 LDGDGLAALLPEAPV 171
|
|
| DEXHc_DHX9 |
cd17972 |
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ... |
64-242 |
2.75e-39 |
|
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ATP-dependent RNA helicase A or RHA and leukophysin or LKP) plays an important role in many cellular processes, including regulation of DNA replication, transcription, translation, microRNA biogenesis, RNA processing and transport, and maintenance of genomic stability. DHX9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350730 [Multi-domain] Cd Length: 234 Bit Score: 146.13 E-value: 2.75e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 64 RIRLPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCL-EWITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVE 142
Cdd:cd17972 56 RELLPVKKFREEILEAISNNPVVIIRGATGCGKTTQVPQYILdDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEE 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 143 LGQEVGYSIRFEDCTSS-RTLMKYMTDGMLLRegMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVM 221
Cdd:cd17972 136 VGKSCGYSVRFESVLPRpHASILFCTVGVLLR--KLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPDLRVILM 213
|
170 180
....*....|....*....|.
gi 1892353677 222 SATLDAGKFQEYFSKAPLMTV 242
Cdd:cd17972 214 SATIDTSMFCEYFFNCPVIEV 234
|
|
| DEXHc_DHX9 |
cd17972 |
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ... |
540-718 |
2.75e-39 |
|
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ATP-dependent RNA helicase A or RHA and leukophysin or LKP) plays an important role in many cellular processes, including regulation of DNA replication, transcription, translation, microRNA biogenesis, RNA processing and transport, and maintenance of genomic stability. DHX9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350730 [Multi-domain] Cd Length: 234 Bit Score: 146.13 E-value: 2.75e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 540 RIRLPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCL-EWITGRYPTKKAVACTQPRRVAAMSVAQRVSEEMDVE 618
Cdd:cd17972 56 RELLPVKKFREEILEAISNNPVVIIRGATGCGKTTQVPQYILdDFIQNDRAAECNIVVTQPRRISAVSVAERVAFERGEE 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 619 LGQEVGYSIRFEDCTSS-RTLMKYMTDGMLLRegMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMDLKIVVM 697
Cdd:cd17972 136 VGKSCGYSVRFESVLPRpHASILFCTVGVLLR--KLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPDLRVILM 213
|
170 180
....*....|....*....|.
gi 1892353677 698 SATLDAGKFQEYFSKAPLMTV 718
Cdd:cd17972 214 SATIDTSMFCEYFFNCPVIEV 234
|
|
| DEXHc_TDRD9 |
cd17988 |
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also ... |
67-235 |
3.91e-34 |
|
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also known as HIG-1or NET54 or C14orf75) is a part of the nuclear PIWI-interacting RNA (piRNA) pathway essential for transposon silencing and male fertility TDRD9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350746 [Multi-domain] Cd Length: 180 Bit Score: 129.16 E-value: 3.91e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 67 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEwitgRYPTKKA---VACTQPRRVAAMSVAQRVSEEMDVEL 143
Cdd:cd17988 1 LPIYAKREEILSLIEANSVVIIKGATGCGKTTQLPQFILD----HYYKRGKycnIVVTQPRRIAAISIARRVSQEREWTL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 144 GQEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMD-LKIVVMS 222
Cdd:cd17988 77 GSLVGYQVGLERPASEETRLIYCTTGVLLQKLINNKTLTEYTHIILDEVHERDQELDFLLLVVRRLLRTNSRhVKIILMS 156
|
170
....*....|...
gi 1892353677 223 ATLDAGKFQEYFS 235
Cdd:cd17988 157 ATISCKEFADYFT 169
|
|
| DEXHc_TDRD9 |
cd17988 |
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also ... |
543-711 |
3.91e-34 |
|
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also known as HIG-1or NET54 or C14orf75) is a part of the nuclear PIWI-interacting RNA (piRNA) pathway essential for transposon silencing and male fertility TDRD9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350746 [Multi-domain] Cd Length: 180 Bit Score: 129.16 E-value: 3.91e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 543 LPVWEYKENFFKVISENQVTVLVGETGSGKTTQIPQWCLEwitgRYPTKKA---VACTQPRRVAAMSVAQRVSEEMDVEL 619
Cdd:cd17988 1 LPIYAKREEILSLIEANSVVIIKGATGCGKTTQLPQFILD----HYYKRGKycnIVVTQPRRIAAISIARRVSQEREWTL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 620 GQEVGYSIRFEDCTSSRTLMKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIKQRMD-LKIVVMS 698
Cdd:cd17988 77 GSLVGYQVGLERPASEETRLIYCTTGVLLQKLINNKTLTEYTHIILDEVHERDQELDFLLLVVRRLLRTNSRhVKIILMS 156
|
170
....*....|...
gi 1892353677 699 ATLDAGKFQEYFS 711
Cdd:cd17988 157 ATISCKEFADYFT 169
|
|
| OB_NTP_bind |
pfam07717 |
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus ... |
1031-1107 |
1.21e-28 |
|
Oligonucleotide/oligosaccharide-binding (OB)-fold; This family is found towards the C-terminus of the DEAD-box helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. There do seem to be a couple of instances where it occurs by itself -. The structure PDB:3i4u adopts an OB-fold. helicases (pfam00270). In these helicases it is apparently always found in association with pfam04408. This C-terminal domain of the yeast helicase contains an oligonucleotide/oligosaccharide-binding (OB)-fold which seems to be placed at the entrance of the putative nucleic acid cavity. It also constitutes the binding site for the G-patch-containing domain of Pfa1p. When found on DEAH/RHA helicases, this domain is central to the regulation of the helicase activity through its binding of both RNA and G-patch domain proteins.
Pssm-ID: 400182 [Multi-domain] Cd Length: 82 Bit Score: 110.03 E-value: 1.21e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 1031 IRKALVSGFFMQVAHLERTGH-YLTVKDNQVVQLHPSTVL----DHKPEWVLYNEFVLTTKNYIRTVTEVKPDWLIRVAP 1105
Cdd:pfam07717 1 LRAALAAGLYPNVARRDPKGKgYTTLSDNQRVFIHPSSVLfnekTFPPEWVVYQELVETTKVYIRTVTAISPEWLLLFAP 80
|
..
gi 1892353677 1106 QY 1107
Cdd:pfam07717 81 HI 82
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
537-728 |
2.02e-24 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 102.18 E-value: 2.02e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 537 FRKRIRLPVWEYKENFFKVISEN-QVTVLVGETGSGKTTQIPQWCLEWItGRYPTKKAVaCTQPRRVAAMSVAQRVSEEM 615
Cdd:smart00487 1 IEKFGFEPLRPYQKEAIEALLSGlRDVILAAPTGSGKTLAALLPALEAL-KRGKGGRVL-VLVPTRELAEQWAEELKKLG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 616 DVELGQEVGY------SIRFEDCTSSRTLMKYMTDGMLLREGMSDPL-LESYGVILLDEAHERT--LATDILMGLLKEII 686
Cdd:smart00487 79 PSLGLKVVGLyggdskREQLRKLESGKTDILVTTPGRLLDLLENDKLsLSNVDLVILDEAHRLLdgGFGDQLEKLLKLLP 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1892353677 687 KQRmdlKIVVMSATL--DAGKFQEYFSKAPLMTVPGRT--HPVEIF 728
Cdd:smart00487 159 KNV---QLLLLSATPpeEIENLLELFLNDPVFIDVGFTplEPIEQF 201
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
61-252 |
2.02e-24 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 102.18 E-value: 2.02e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 61 FRKRIRLPVWEYKENFFKVISEN-QVTVLVGETGSGKTTQIPQWCLEWItGRYPTKKAVaCTQPRRVAAMSVAQRVSEEM 139
Cdd:smart00487 1 IEKFGFEPLRPYQKEAIEALLSGlRDVILAAPTGSGKTLAALLPALEAL-KRGKGGRVL-VLVPTRELAEQWAEELKKLG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 140 DVELGQEVGY------SIRFEDCTSSRTLMKYMTDGMLLREGMSDPL-LESYGVILLDEAHERT--LATDILMGLLKEII 210
Cdd:smart00487 79 PSLGLKVVGLyggdskREQLRKLESGKTDILVTTPGRLLDLLENDKLsLSNVDLVILDEAHRLLdgGFGDQLEKLLKLLP 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1892353677 211 KQRmdlKIVVMSATL--DAGKFQEYFSKAPLMTVPGRT--HPVEIF 252
Cdd:smart00487 159 KNV---QLLLLSATPpeEIENLLELFLNDPVFIDVGFTplEPIEQF 201
|
|
| HA2 |
pfam04408 |
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in ... |
469-529 |
1.20e-23 |
|
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 461295 [Multi-domain] Cd Length: 104 Bit Score: 96.54 E-value: 1.20e-23
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1892353677 469 ALELLNYLAALDDDGNLTDLGSMMAEFPLDPQLAKMVMASCDFNCSNEVLSITAMLSGK-PF 529
Cdd:pfam04408 1 ALELLYYLGALDEDGELTPLGRKMAELPLDPRLAKMLLAAAELGCLDEVLTIVAALSVRdPF 62
|
|
| HA2 |
smart00847 |
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino ... |
475-532 |
3.30e-19 |
|
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 214852 [Multi-domain] Cd Length: 82 Bit Score: 83.09 E-value: 3.30e-19
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1892353677 475 YLAALDDDGNLTDLGSMMAEFPLDPQLAKMVMASCDFNCSNEVLSITAMLSGKPFSAR 532
Cdd:smart00847 1 ELGALDDDGRLTPLGRKMAELPLDPRLAKMLLAAAEFGCLDEILTIVAMLSVGDPRPK 58
|
|
| PHA02653 |
PHA02653 |
RNA helicase NPH-II; Provisional |
83-416 |
3.92e-13 |
|
RNA helicase NPH-II; Provisional
Pssm-ID: 177443 [Multi-domain] Cd Length: 675 Bit Score: 73.86 E-value: 3.92e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 83 NQVTVLVGETGSGKTTQIPQ--WCLEWITGRYPT---------KKAVACTQPRR--VAAMSVAQRVSeemdveLGqevgy 149
Cdd:PHA02653 179 RKPVVLTGGTGVGKTSQVPKllLWFNYLFGGFDNldkidpnfiERPIVLSLPRValVRLHSITLLKS------LG----- 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 150 sirFEDCTSSRTLMKY--MTDGMLLREGMSDPL-----------LESYGVILLDEAHERTLATDILMGLL-KEIIKQRmd 215
Cdd:PHA02653 248 ---FDEIDGSPISLKYgsIPDELINTNPKPYGLvfsthkltlnkLFDYGTVIIDEVHEHDQIGDIIIAVArKHIDKIR-- 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 216 lKIVVMSATL--DAGKFQEYFSKAPLMTVPGRT-HPV-EIF----YTPEPERDYLEAAIRTVIQ-IHMCEEVEG-DILLF 285
Cdd:PHA02653 323 -SLFLMTATLedDRDRIKEFFPNPAFVHIPGGTlFPIsEVYvknkYNPKNKRAYIEEEKKNIVTaLKKYTPPKGsSGIVF 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 286 LTGQEEIEEACKRIQREVDGLG--------PDVGELRCiPLYSTLPPNlqqrifdppppkrangaigrkIVVSTNIAETS 357
Cdd:PHA02653 402 VASVSQCEEYKKYLEKRLPIYDfyiihgkvPNIDEILE-KVYSSKNPS---------------------IIISTPYLESS 459
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1892353677 358 LTIDGVVFVIDPGfakqKVYNP-----RIRVesllvtaISKASAQQRAGRAGRTKPGKCFRLYT 416
Cdd:PHA02653 460 VTIRNATHVYDTG----RVYVPepfggKEMF-------ISKSMRTQRKGRVGRVSPGTYVYFYD 512
|
|
| PHA02653 |
PHA02653 |
RNA helicase NPH-II; Provisional |
559-892 |
3.92e-13 |
|
RNA helicase NPH-II; Provisional
Pssm-ID: 177443 [Multi-domain] Cd Length: 675 Bit Score: 73.86 E-value: 3.92e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 559 NQVTVLVGETGSGKTTQIPQ--WCLEWITGRYPT---------KKAVACTQPRR--VAAMSVAQRVSeemdveLGqevgy 625
Cdd:PHA02653 179 RKPVVLTGGTGVGKTSQVPKllLWFNYLFGGFDNldkidpnfiERPIVLSLPRValVRLHSITLLKS------LG----- 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 626 sirFEDCTSSRTLMKY--MTDGMLLREGMSDPL-----------LESYGVILLDEAHERTLATDILMGLL-KEIIKQRmd 691
Cdd:PHA02653 248 ---FDEIDGSPISLKYgsIPDELINTNPKPYGLvfsthkltlnkLFDYGTVIIDEVHEHDQIGDIIIAVArKHIDKIR-- 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 692 lKIVVMSATL--DAGKFQEYFSKAPLMTVPGRT-HPV-EIF----YTPEPERDYLEAAIRTVIQ-IHMCEEVEG-DILLF 761
Cdd:PHA02653 323 -SLFLMTATLedDRDRIKEFFPNPAFVHIPGGTlFPIsEVYvknkYNPKNKRAYIEEEKKNIVTaLKKYTPPKGsSGIVF 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 762 LTGQEEIEEACKRIQREVDGLG--------PDVGELRCiPLYSTLPPNlqqrifdppppkrangaigrkIVVSTNIAETS 833
Cdd:PHA02653 402 VASVSQCEEYKKYLEKRLPIYDfyiihgkvPNIDEILE-KVYSSKNPS---------------------IIISTPYLESS 459
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1892353677 834 LTIDGVVFVIDPGfakqKVYNP-----RIRVesllvtaISKASAQQRAGRAGRTKPGKCFRLYT 892
Cdd:PHA02653 460 VTIRNATHVYDTG----RVYVPepfggKEMF-------ISKSMRTQRKGRVGRVSPGTYVYFYD 512
|
|
| HELICc |
smart00490 |
helicase superfamily c-terminal domain; |
312-405 |
3.75e-10 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 197757 [Multi-domain] Cd Length: 82 Bit Score: 57.22 E-value: 3.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 312 ELRCIPLYSTLPPNLQQRIFDPPPPKRangaigRKIVVSTNIAETSLTIDGVVFVIDPGFakqkvynprirvesllvtAI 391
Cdd:smart00490 11 GIKVARLHGGLSQEEREEILDKFNNGK------IKVLVATDVAERGLDLPGVDLVIIYDL------------------PW 66
|
90
....*....|....
gi 1892353677 392 SKASAQQRAGRAGR 405
Cdd:smart00490 67 SPASYIQRIGRAGR 80
|
|
| HELICc |
smart00490 |
helicase superfamily c-terminal domain; |
788-881 |
3.75e-10 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 197757 [Multi-domain] Cd Length: 82 Bit Score: 57.22 E-value: 3.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 788 ELRCIPLYSTLPPNLQQRIFDPPPPKRangaigRKIVVSTNIAETSLTIDGVVFVIDPGFakqkvynprirvesllvtAI 867
Cdd:smart00490 11 GIKVARLHGGLSQEEREEILDKFNNGK------IKVLVATDVAERGLDLPGVDLVIIYDL------------------PW 66
|
90
....*....|....
gi 1892353677 868 SKASAQQRAGRAGR 881
Cdd:smart00490 67 SPASYIQRIGRAGR 80
|
|
| DEXHc_viral_Ns3 |
cd17931 |
DEXH-box helicase domain of NS3 protease-helicase; NS3 is a nonstructural multifunctional ... |
84-224 |
7.16e-09 |
|
DEXH-box helicase domain of NS3 protease-helicase; NS3 is a nonstructural multifunctional protein found in pestiviruses that contains an N-terminal protease and a C-terminal helicase. The N-terminal domain is a chymotrypsin-like serine protease, which is responsible for most of the maturation cleavages of the polyprotein precursor in the cytosolic side of the endoplasmic reticulum membrane. The C-terminal domain, about two-thirds of NS3, is a helicase belonging to superfamily 2 (SF2) thought to be important for unwinding highly structured regions of the RNA genome during replication. NS3 plays an essential role in viral polyprotein processing and genome replication. NS3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350689 [Multi-domain] Cd Length: 151 Bit Score: 55.63 E-value: 7.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 84 QVTVLVGETGSGKTTQIPQwclEWITGRYPTKKAVACTQPRRVAAMSVAQRVSeemdvelGQEVGYSI-RFEDCTSSRTL 162
Cdd:cd17931 2 QLTVLDLHPGAGKTTRVLP---QIIREAIKKRLRTLVLAPTRVVAAEMYEALR-------GLPIRYRTgAVKEEHGGNEI 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1892353677 163 MKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIkQRMDLKIVVMSAT 224
Cdd:cd17931 72 VDYMCHGTFTCRLLSPKRVPNYNLIIMDEAHFTDPASIAARGYIHTRV-EMGEAAVIFMTAT 132
|
|
| DEXHc_viral_Ns3 |
cd17931 |
DEXH-box helicase domain of NS3 protease-helicase; NS3 is a nonstructural multifunctional ... |
560-700 |
7.16e-09 |
|
DEXH-box helicase domain of NS3 protease-helicase; NS3 is a nonstructural multifunctional protein found in pestiviruses that contains an N-terminal protease and a C-terminal helicase. The N-terminal domain is a chymotrypsin-like serine protease, which is responsible for most of the maturation cleavages of the polyprotein precursor in the cytosolic side of the endoplasmic reticulum membrane. The C-terminal domain, about two-thirds of NS3, is a helicase belonging to superfamily 2 (SF2) thought to be important for unwinding highly structured regions of the RNA genome during replication. NS3 plays an essential role in viral polyprotein processing and genome replication. NS3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350689 [Multi-domain] Cd Length: 151 Bit Score: 55.63 E-value: 7.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 560 QVTVLVGETGSGKTTQIPQwclEWITGRYPTKKAVACTQPRRVAAMSVAQRVSeemdvelGQEVGYSI-RFEDCTSSRTL 638
Cdd:cd17931 2 QLTVLDLHPGAGKTTRVLP---QIIREAIKKRLRTLVLAPTRVVAAEMYEALR-------GLPIRYRTgAVKEEHGGNEI 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1892353677 639 MKYMTDGMLLREGMSDPLLESYGVILLDEAHERTLATDILMGLLKEIIkQRMDLKIVVMSAT 700
Cdd:cd17931 72 VDYMCHGTFTCRLLSPKRVPNYNLIIMDEAHFTDPASIAARGYIHTRV-EMGEAAVIFMTAT 132
|
|
| Helicase_C |
pfam00271 |
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
266-405 |
2.38e-07 |
|
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 50.29 E-value: 2.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 266 IRTVIQIHMCEEvEGDILLFLTGQEEIEeaCKRIQREvdglgpdvGELRCIPLYSTLPPNLQQRIFDPPPPKRangaigR 345
Cdd:pfam00271 3 LEALLELLKKER-GGKVLIFSQTKKTLE--AELLLEK--------EGIKVARLHGDLSQEEREEILEDFRKGK------I 65
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 346 KIVVSTNIAETSLTIDGVVFVIDPGFakqkVYNPrirvesllvtaiskASAQQRAGRAGR 405
Cdd:pfam00271 66 DVLVATDVAERGLDLPDVDLVINYDL----PWNP--------------ASYIQRIGRAGR 107
|
|
| Helicase_C |
pfam00271 |
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
742-881 |
2.38e-07 |
|
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 50.29 E-value: 2.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 742 IRTVIQIHMCEEvEGDILLFLTGQEEIEeaCKRIQREvdglgpdvGELRCIPLYSTLPPNLQQRIFDPPPPKRangaigR 821
Cdd:pfam00271 3 LEALLELLKKER-GGKVLIFSQTKKTLE--AELLLEK--------EGIKVARLHGDLSQEEREEILEDFRKGK------I 65
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 822 KIVVSTNIAETSLTIDGVVFVIDPGFakqkVYNPrirvesllvtaiskASAQQRAGRAGR 881
Cdd:pfam00271 66 DVLVATDVAERGLDLPDVDLVINYDL----PWNP--------------ASYIQRIGRAGR 107
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
77-226 |
2.65e-06 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 48.78 E-value: 2.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 77 FKVISENQVTVLVGETGSGKTT--QIPqwCLEWITGRYPTKKAVaCTQPRRVAAMSVAQRVSeemdvELGQEVGYSIRFE 154
Cdd:pfam00270 8 IPAILEGRDVLVQAPTGSGKTLafLLP--ALEALDKLDNGPQAL-VLAPTRELAEQIYEELK-----KLGKGLGLKVASL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 155 DCTSSRTLMK---------YMTDGMLLREGMSDPLLESYGVILLDEAHErtLATDILMGLLKEIIKQ-RMDLKIVVMSAT 224
Cdd:pfam00270 80 LGGDSRKEQLeklkgpdilVGTPGRLLDLLQERKLLKNLKLLVLDEAHR--LLDMGFGPDLEEILRRlPKKRQILLLSAT 157
|
..
gi 1892353677 225 LD 226
Cdd:pfam00270 158 LP 159
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
553-702 |
2.65e-06 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 48.78 E-value: 2.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 553 FKVISENQVTVLVGETGSGKTT--QIPqwCLEWITGRYPTKKAVaCTQPRRVAAMSVAQRVSeemdvELGQEVGYSIRFE 630
Cdd:pfam00270 8 IPAILEGRDVLVQAPTGSGKTLafLLP--ALEALDKLDNGPQAL-VLAPTRELAEQIYEELK-----KLGKGLGLKVASL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 631 DCTSSRTLMK---------YMTDGMLLREGMSDPLLESYGVILLDEAHErtLATDILMGLLKEIIKQ-RMDLKIVVMSAT 700
Cdd:pfam00270 80 LGGDSRKEQLeklkgpdilVGTPGRLLDLLQERKLLKNLKLLVLDEAHR--LLDMGFGPDLEEILRRlPKKRQILLLSAT 157
|
..
gi 1892353677 701 LD 702
Cdd:pfam00270 158 LP 159
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
86-224 |
5.95e-06 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 47.40 E-value: 5.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 86 TVLVGETGSGKTTQIPQWcLEWITGRYPTKKAVACtqPRRVAAMSVAQRVSEEMDveLGQEVGYSIRFEDcTSSRTLMK- 164
Cdd:cd00046 4 VLITAPTGSGKTLAALLA-ALLLLLKKGKKVLVLV--PTKALALQTAERLRELFG--PGIRVAVLVGGSS-AEEREKNKl 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1892353677 165 ------YMTDGMLLREGMSDPLLES--YGVILLDEAHERTLATD-ILMGLLKEIIKQRMDLKIVVMSAT 224
Cdd:cd00046 78 gdadiiIATPDMLLNLLLREDRLFLkdLKLIIVDEAHALLIDSRgALILDLAVRKAGLKNAQVILLSAT 146
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
562-700 |
5.95e-06 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 47.40 E-value: 5.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 562 TVLVGETGSGKTTQIPQWcLEWITGRYPTKKAVACtqPRRVAAMSVAQRVSEEMDveLGQEVGYSIRFEDcTSSRTLMK- 640
Cdd:cd00046 4 VLITAPTGSGKTLAALLA-ALLLLLKKGKKVLVLV--PTKALALQTAERLRELFG--PGIRVAVLVGGSS-AEEREKNKl 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1892353677 641 ------YMTDGMLLREGMSDPLLES--YGVILLDEAHERTLATD-ILMGLLKEIIKQRMDLKIVVMSAT 700
Cdd:cd00046 78 gdadiiIATPDMLLNLLLREDRLFLkdLKLIIVDEAHALLIDSRgALILDLAVRKAGLKNAQVILLSAT 146
|
|
| SF2_C |
cd18785 |
C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases ... |
346-415 |
1.96e-04 |
|
C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases include DEAD-box helicases, UvrB, RecG, Ski2, Sucrose Non-Fermenting (SNF) family helicases, and dicer proteins, among others. Similar to SF1 helicases, they do not form toroidal structures like SF3-6 helicases. SF2 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350172 [Multi-domain] Cd Length: 77 Bit Score: 41.15 E-value: 1.96e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1892353677 346 KIVVSTNIAETSLTIDGVVFVIDPGFAkqkvynprirvesllvtaISKASAQQRAGRAGR--TKPGKCFRLY 415
Cdd:cd18785 24 EILVATNVLGEGIDVPSLDTVIFFDPP------------------SSAASYIQRVGRAGRggKDEGEVILFV 77
|
|
| SF2_C |
cd18785 |
C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases ... |
822-891 |
1.96e-04 |
|
C-terminal helicase domain of superfamily 2 DEAD/H-box helicases; Superfamily (SF)2 helicases include DEAD-box helicases, UvrB, RecG, Ski2, Sucrose Non-Fermenting (SNF) family helicases, and dicer proteins, among others. Similar to SF1 helicases, they do not form toroidal structures like SF3-6 helicases. SF2 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350172 [Multi-domain] Cd Length: 77 Bit Score: 41.15 E-value: 1.96e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1892353677 822 KIVVSTNIAETSLTIDGVVFVIDPGFAkqkvynprirvesllvtaISKASAQQRAGRAGR--TKPGKCFRLY 891
Cdd:cd18785 24 EILVATNVLGEGIDVPSLDTVIFFDPP------------------SSAASYIQRVGRAGRggKDEGEVILFV 77
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
84-193 |
1.45e-03 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 40.02 E-value: 1.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 84 QVTVLVGETGSGKTTQIpQWCLEWITGRYPTKKAVACTQPRrvAAMSVAQRVSEEMDVELgqevgysirfEDCTSSRTLM 163
Cdd:pfam13401 6 GILVLTGESGTGKTTLL-RRLLEQLPEVRDSVVFVDLPSGT--SPKDLLRALLRALGLPL----------SGRLSKEELL 72
|
90 100 110
....*....|....*....|....*....|
gi 1892353677 164 KYMTDgmLLREGMSDPllesygVILLDEAH 193
Cdd:pfam13401 73 AALQQ--LLLALAVAV------VLIIDEAQ 94
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
560-669 |
1.45e-03 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 40.02 E-value: 1.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1892353677 560 QVTVLVGETGSGKTTQIpQWCLEWITGRYPTKKAVACTQPRrvAAMSVAQRVSEEMDVELgqevgysirfEDCTSSRTLM 639
Cdd:pfam13401 6 GILVLTGESGTGKTTLL-RRLLEQLPEVRDSVVFVDLPSGT--SPKDLLRALLRALGLPL----------SGRLSKEELL 72
|
90 100 110
....*....|....*....|....*....|
gi 1892353677 640 KYMTDgmLLREGMSDPllesygVILLDEAH 669
Cdd:pfam13401 73 AALQQ--LLLALAVAV------VLIIDEAQ 94
|
|
| |
