NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1891598287|ref|WP_183830238|]
View 

iron ABC transporter permease [Rhizobium cellulosilyticum]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 36-343 1.01e-90

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 273.87  E-value: 1.01e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  36 SASVGRFSIPLADVLNIVGRWlsgalAPETMEERILINVRVPRILLAAIVGAGLALCGAALQALFRNPLVSPRVLGVSSG 115
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGP-----DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 116 AALGGALTLLIGGGATVLF--AATFSSALFALVLVAVISRVAGR-TILSIVLAGIVIDALFSAMISLTQYVADPETsLPA 192
Cdd:COG0609    76 AALGAVLAIVLGGGLSALGlpLAAFLGALLAALLVYLLARRGGGlSPLRLVLAGVAVSALFSALTSLLLLLADPEQ-LRS 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 193 IVFWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVLSMGDEEARSFGVNVGFSRWFVFSVISVIIGGCVAVSGVI 272
Cdd:COG0609   155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1891598287 273 GWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLARAIIS-AELPLGILTAVIGAPVFIYLLCTRQ 343
Cdd:COG0609   235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILApAELPVGIVTALIGAPFFLYLLRRRR 306
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 36-343 1.01e-90

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 273.87  E-value: 1.01e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  36 SASVGRFSIPLADVLNIVGRWlsgalAPETMEERILINVRVPRILLAAIVGAGLALCGAALQALFRNPLVSPRVLGVSSG 115
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGP-----DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 116 AALGGALTLLIGGGATVLF--AATFSSALFALVLVAVISRVAGR-TILSIVLAGIVIDALFSAMISLTQYVADPETsLPA 192
Cdd:COG0609    76 AALGAVLAIVLGGGLSALGlpLAAFLGALLAALLVYLLARRGGGlSPLRLVLAGVAVSALFSALTSLLLLLADPEQ-LRS 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 193 IVFWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVLSMGDEEARSFGVNVGFSRWFVFSVISVIIGGCVAVSGVI 272
Cdd:COG0609   155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1891598287 273 GWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLARAIIS-AELPLGILTAVIGAPVFIYLLCTRQ 343
Cdd:COG0609   235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILApAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 28-339 8.82e-69

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 217.78  E-value: 8.82e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  28 IFAVAVIVSASVGRFSIPLADVLNIVGRWLSGalapetMEERILINVRVPRILLAAIVGAGLALCGAALQALFRNPLVSP 107
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGDDS------LAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 108 RVLGVSSGAALGGALTLLIGGGA---TVLFAATFSSALFALVLVAVISRVAGRTILSIVLAGIVIDALFSAMISLTQYVA 184
Cdd:pfam01032  75 SILGISSGAALGAVLAILLGGSLslfALPLAAFIGALLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSLLLLLL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 185 DPEtSLPAIVFWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVLSMGDEEARSFGVNVGFSRWFVFSVISVIIGG 264
Cdd:pfam01032 155 NPE-ALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAA 233

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1891598287 265 CVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLARAIIS-AELPLGILTAVIGAPVFIYLL 339
Cdd:pfam01032 234 SVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSpYELPVGIVTALIGAPFFIYLL 309
btuC PRK09535
cobalamin ABC transporter permease BtuC;
16-345 7.98e-58

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 191.50  E-value: 7.98e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  16 ARAVVHWSSLLLIFAVAVIVSASVGRFSIPLADV-----------------------LNIVGRWLSGALA--------PE 64
Cdd:PRK09535    5 GRAVAWSAGLTALLVAVVLVSAAIGPVRIPPRTVamallnavavpvgvavtthgvpvLSVGLSLPAPDLEyaspfsfaVP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  65 TMEERILINVRVPRILLAAIVGAGLALCGAALQALFRNPLVSPRVLGVSSGAALGGALTLLIGGGATV-LFAATFSSALF 143
Cdd:PRK09535   85 ETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAVPFgLQAAAFAGALV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 144 ALVLVAVISRVAGRT-ILSIVLAGIVIDALFSAMISLTQYVADpeTSLPAIVFWLMGSFSSASWKKVGEHGPVILLAIII 222
Cdd:PRK09535  165 AAFGVYAIATENGRTpVATLLLAGVAVQTFLGAVISYLLLHSG--ESLRRAVYWLMGHLHGSTWSDVEVALPVVVVGFVV 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 223 LYRLRFRIAVLSMGDEEARSFGVNVGFSRWFVFSVISVIIGGCVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLG 302
Cdd:PRK09535  243 LLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLPTSALAG 322

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 1891598287 303 ASFMVVIDTLARAiISAELPLGILTAVIGAPVFIYLLCTRQAR 345
Cdd:PRK09535  323 ASFLVATDTVARS-GPAEVPVGIVTAALGAPFFLYLLRTREVH 364
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 79-339 2.34e-46

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 158.49  E-value: 2.34e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  79 ILLAAIVGAGLALCGAALQALFRNPLVSPRVLGVSSGAALGGALTLLIGGGATVLFAATFSSALFALVLVAV--ISRVAG 156
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVllLASRGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 157 RTILSIVLAGIVIDALFSAMISLTQYVADPetSLPAIVFWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVLSMG 236
Cdd:cd06550    81 LSPSKLILIGIVLSAFFSAGVILISLLSDD--SLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 237 DEEARSFGVNVGFSRWFVFSVISVIIGGCVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLARAI 316
Cdd:cd06550   159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL 238

                         250       260
                  ....*....|....*....|...
gi 1891598287 317 ISAELPLGILTAVIGAPVFIYLL 339
Cdd:cd06550   239 LPSELPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 36-343 1.01e-90

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 273.87  E-value: 1.01e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  36 SASVGRFSIPLADVLNIVGRWlsgalAPETMEERILINVRVPRILLAAIVGAGLALCGAALQALFRNPLVSPRVLGVSSG 115
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGP-----DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 116 AALGGALTLLIGGGATVLF--AATFSSALFALVLVAVISRVAGR-TILSIVLAGIVIDALFSAMISLTQYVADPETsLPA 192
Cdd:COG0609    76 AALGAVLAIVLGGGLSALGlpLAAFLGALLAALLVYLLARRGGGlSPLRLVLAGVAVSALFSALTSLLLLLADPEQ-LRS 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 193 IVFWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVLSMGDEEARSFGVNVGFSRWFVFSVISVIIGGCVAVSGVI 272
Cdd:COG0609   155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1891598287 273 GWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLARAIIS-AELPLGILTAVIGAPVFIYLLCTRQ 343
Cdd:COG0609   235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILApAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 28-339 8.82e-69

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 217.78  E-value: 8.82e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  28 IFAVAVIVSASVGRFSIPLADVLNIVGRWLSGalapetMEERILINVRVPRILLAAIVGAGLALCGAALQALFRNPLVSP 107
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGDDS------LAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 108 RVLGVSSGAALGGALTLLIGGGA---TVLFAATFSSALFALVLVAVISRVAGRTILSIVLAGIVIDALFSAMISLTQYVA 184
Cdd:pfam01032  75 SILGISSGAALGAVLAILLGGSLslfALPLAAFIGALLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSLLLLLL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 185 DPEtSLPAIVFWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVLSMGDEEARSFGVNVGFSRWFVFSVISVIIGG 264
Cdd:pfam01032 155 NPE-ALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAA 233

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1891598287 265 CVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLARAIIS-AELPLGILTAVIGAPVFIYLL 339
Cdd:pfam01032 234 SVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSpYELPVGIVTALIGAPFFIYLL 309
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 25-344 4.54e-60

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 195.84  E-value: 4.54e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  25 LLLIFAVAVIVSASVGRFSIPLADVLNivgrwlsgalapeTMEERILINVRVPRILLAAIVGAGLALCGAALQALFRNPL 104
Cdd:COG4139    18 LLLLLLLLFVLSLCAGEVWIPPTQWLS-------------EAWQLFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 105 VSPRVLGVSSGAALGGALTLLIGGGAT----VLFAATFSSALFALVLVAVISRVagRTILSIVLAGIVIDALFSAMISLT 180
Cdd:COG4139    85 AEPGLLGISNGAGVGLVLVVLLGGGLLppwlLSLAAIAGALLVTLLLLAFARRR--LSNARLLLIGVALGIICSAIMTWA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 181 QYVADPEtSLPAIVFWLMGSFSSASWKkvgeHGPVILLAIIILYRLRFRIAVL---SMGDEEARSFGVNVGFSRWFVFSV 257
Cdd:COG4139   163 VYFSSSL-DLRQLMYWMMGSFGGVDWR----QLWLLLALLPVLLWLCLQGKPLnllLLGENQARQLGLSVHRWRNLLVLA 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 258 ISVIIGGCVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLAR-AIISAELPLGILTAVIGAPVFI 336
Cdd:COG4139   238 TGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAALLLLADIIARlALSSAELPIGVVTATLGAPVFI 317


                  ....*...
gi 1891598287 337 YLLCTRQA 344
Cdd:COG4139   318 WLLLRRRK 325
btuC PRK09535
cobalamin ABC transporter permease BtuC;
16-345 7.98e-58

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 191.50  E-value: 7.98e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  16 ARAVVHWSSLLLIFAVAVIVSASVGRFSIPLADV-----------------------LNIVGRWLSGALA--------PE 64
Cdd:PRK09535    5 GRAVAWSAGLTALLVAVVLVSAAIGPVRIPPRTVamallnavavpvgvavtthgvpvLSVGLSLPAPDLEyaspfsfaVP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  65 TMEERILINVRVPRILLAAIVGAGLALCGAALQALFRNPLVSPRVLGVSSGAALGGALTLLIGGGATV-LFAATFSSALF 143
Cdd:PRK09535   85 ETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAVPFgLQAAAFAGALV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 144 ALVLVAVISRVAGRT-ILSIVLAGIVIDALFSAMISLTQYVADpeTSLPAIVFWLMGSFSSASWKKVGEHGPVILLAIII 222
Cdd:PRK09535  165 AAFGVYAIATENGRTpVATLLLAGVAVQTFLGAVISYLLLHSG--ESLRRAVYWLMGHLHGSTWSDVEVALPVVVVGFVV 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 223 LYRLRFRIAVLSMGDEEARSFGVNVGFSRWFVFSVISVIIGGCVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLG 302
Cdd:PRK09535  243 LLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLPTSALAG 322

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 1891598287 303 ASFMVVIDTLARAiISAELPLGILTAVIGAPVFIYLLCTRQAR 345
Cdd:PRK09535  323 ASFLVATDTVARS-GPAEVPVGIVTAALGAPFFLYLLRTREVH 364
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 25-345 6.01e-54

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 180.15  E-value: 6.01e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  25 LLLIFAVAVIVSASVGRFSIPLADvlnivgrWLSGalapetMEERILINVRVPRILLAAIVGAGLALCGAALQALFRNPL 104
Cdd:PRK03784   21 LSVLLLLALLLSLCAGEQWISPGD-------WLSP------RGELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 105 VSPRVLGVSSGAALGGALTLLIGGGATVLFAATFSSALFALVLVAVISRVAGRTILS---IVLAGIVIDALFSAMISLTQ 181
Cdd:PRK03784   88 AEPGLLGVSNGAGVALVAAVLLGQGLLPPWALSLCAIAGALLITLILLRFARRHRLStsrLLLAGVALGIICSALMTWAV 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 182 YVADpETSLPAIVFWLMGSFSSASWKkvgeHGPVILLAIIILYRLRFR---IAVLSMGDEEARSFGVNVGFSRWFVFSVI 258
Cdd:PRK03784  168 YFST-SLDLRQLMYWMMGGFGGVDWR----QSWLMLALLPVLIWLCCQgrpLNMLALGEISARQLGLPLWFWRNLLVLAT 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 259 SVIIGGCVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLAR-AIISAELPLGILTAVIGAPVFIY 337
Cdd:PRK03784  243 GWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLLLLADIVARlALASAELPIGVVTATLGAPVFIW 322


                  ....*...
gi 1891598287 338 LLCTRQAR 345
Cdd:PRK03784  323 LLLRSHRA 330
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
1-339 5.13e-50

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 176.95  E-value: 5.13e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287   1 MTLPLAGTGHPDQPTARAVVHWS-SLLLIFAVAVIVSASVGRFSIPLadvlnivgRWLSGALAPETMEERilinvrVPRI 79
Cdd:PRK10577  336 QSAPAMSAGDRVAARRRRVLAWLlALGLLLLLALVVALSFGRDAHGW--------NWLSGQLLDALLPLR------LPRL 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  80 LLAAIVGAGLALCGAALQALFRNPLVSPRVLGVSSGAALGGALTLLIGGGA--TVLFAATFSSALFALVLVAVISRVAGR 157
Cdd:PRK10577  402 LAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAgfGWLLAAALLGALAALALILLLARRGGF 481

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 158 TILSIVLAGIVIDALFSAMISLTQYVADPETSlpAIVFWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVLSMGD 237
Cdd:PRK10577  482 APERLLLTGIALSALFTALIQLLLASGDPRAA--QLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGD 559

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 238 EEARSFGVNVGFSRWFVFSVISVIIGGCVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLARAII 317
Cdd:PRK10577  560 DTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLL 639

                         330       340
                  ....*....|....*....|...
gi 1891598287 318 S-AELPLGILTAVIGAPVFIYLL 339
Cdd:PRK10577  640 FpYQIPAGLLAALIGAPYFLWLL 662
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 79-339 2.34e-46

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 158.49  E-value: 2.34e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  79 ILLAAIVGAGLALCGAALQALFRNPLVSPRVLGVSSGAALGGALTLLIGGGATVLFAATFSSALFALVLVAV--ISRVAG 156
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVllLASRGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 157 RTILSIVLAGIVIDALFSAMISLTQYVADPetSLPAIVFWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVLSMG 236
Cdd:cd06550    81 LSPSKLILIGIVLSAFFSAGVILISLLSDD--SLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 237 DEEARSFGVNVGFSRWFVFSVISVIIGGCVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLARAI 316
Cdd:cd06550   159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL 238

                         250       260
                  ....*....|....*....|...
gi 1891598287 317 ISAELPLGILTAVIGAPVFIYLL 339
Cdd:cd06550   239 LPSELPVGPVTALLGAPYFLYLL 261
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
63-338 1.01e-44

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 156.01  E-value: 1.01e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  63 PETMEERILINVRVPRILLAAIVGAGLALCGAALQALFRNPLVSPRVLGVSSGAALGGALT-----LLIGGGATVLFAAT 137
Cdd:PRK11228   39 TPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTsalspTPFAGYSLAFIAAC 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 138 FSSALFALVLVAVISRVAGRTILSIVLAGIVIDALFSAMISLTQYVAdpETSLPAIVFWLMGSFSSASWKKVGEHGPVIL 217
Cdd:PRK11228  119 GGGLSWLLVMTAGGGWRHTHDRNRLILAGIALSALCMALTRITLLLA--EDHAYGIFYWLAGGVSHARWQEVWQLLPFVV 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 218 LAIIILYRLRFRIAVLSMGDEEARSFGVNVGFSRWFVFSVISVIIGGCVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGT 297
Cdd:PRK11228  197 TAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIGYDQRNVLPM 276

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1891598287 298 AALLGASFMVVIDTLARAI-ISAELPLGILTAVIGAPVFIYL 338
Cdd:PRK11228  277 SMLLGATLMLLADLLARALaFPGELPAGAVLALIGAPCFVWL 318
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
9-339 1.07e-37

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 142.67  E-value: 1.07e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287   9 GHPDQPTARAVVHWSSLLLIFAVAVIVSASVGRFSIPLADVLNIVgrWLSGALAPETMeerILINVRVPRILLAAIVGAG 88
Cdd:PRK10577    1 MPRLMSRRRARLPALLLALLLLLALALTLTQLSAALPLSQWLQAL--WGPDADDLEQL---LLHYSRLPRLAIALLVGAA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  89 LALCGAALQALFRNPLVSPRVLGVSSGAALGGALTLLIGGGATVL--FAATFSSALFALVLVAVISRVAGRTILSIVLAG 166
Cdd:PRK10577   76 LGLAGALLQQVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALasQLAAFAGGLLAAALVFALAGGKRLSPLRLVLAG 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 167 IVIDALFSAMISLTQYVADPETSlpAIVFWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVLSMGDEEARSFGVN 246
Cdd:PRK10577  156 MVVSLYLGALTTLLLLFNEQYLQ--GLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLA 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 247 VGFSRWFVFSVISVIIGGCVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLARAI---ISAELPL 323
Cdd:PRK10577  234 VSLTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLLagvGGELLPT 313

                         330
                  ....*....|....*.
gi 1891598287 324 GILTAVIGAPVFIYLL 339
Cdd:PRK10577  314 GAVTALIGAPLLLWLL 329
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
24-339 3.33e-36

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 133.25  E-value: 3.33e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  24 SLLLIFAVAVIVSASVGRFSIPLADVLNivgrwlsgALAPETMEERILINVRVPRILLAAIVGAGLALCGAALQALFRNP 103
Cdd:PRK09777    8 FITLALAGCALLSLRMGVIPLPWRALLT--------DWQAGDEHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 104 LVSPRVLGVSSGAALG--GALTLLIGGGATVLFAATFSSALFALVLVAVIsrVAGRTILSIVLAGIVIDALFSamiSLTQ 181
Cdd:PRK09777   80 LASPDILGVNHAASLAsvGALLLFPSLPVMWLPLLAFIGGMAGLILLKML--AGTHQPMKLALTGVALSALWA---SLTD 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 182 YV--ADPETSLPAIVfWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVLSMGDEEARSFGVNVGFSRWFVFSVIS 259
Cdd:PRK09777  155 YLmlSRPQDINNALL-WLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAV 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 260 VIIGGCVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLARAI-ISAELPLGILTAVIGAPVFIYL 338
Cdd:PRK09777  234 ALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIhPPLELPAGVLTAIIGAPWFFWL 313


                  .
gi 1891598287 339 L 339
Cdd:PRK09777  314 L 314
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
25-350 1.24e-29

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 115.96  E-value: 1.24e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  25 LLLIFAVAVIVSASVGRFSIPLADVLNIVGRWLSGAlapetmEERILINVRVPRILLAAIVGAGLALCGAALQALFRNPL 104
Cdd:PRK10441   16 LLLLLIIATALSLLIGAKSLPASVVLEALSGTCQSA------DCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 105 VSPRVLGVSSGAALGGALTLLIGGGATVL--FAATFSSALFALVLVAVISRVAGRTI--LSIVLAGIVIDALFSAM---I 177
Cdd:PRK10441   90 ADPGLLGVNAGASFAIVLGAALFGYSSAQeqLAMAFAGALVASLIVAFTGSQGGGQLspVRLTLAGVALAAVLEGLtsgI 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 178 SLTQYVAdpetsLPAIVFWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVLSMGDEEARSFGVNVGFSRWFVFSV 257
Cdd:PRK10441  170 ALLNPDV-----YDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLIGLLA 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 258 ISVIIGGCVAVSGVIGWVGLVIPHAARLLVGEGHRRFHGTAALLGASFMVVIDTLARAIISAELPLGILTAVIGAPVFIY 337
Cdd:PRK10441  245 ITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRLLVPGELRVSVVSAFIGAPVLIF 324

                         330
                  ....*....|...
gi 1891598287 338 LLctRQARMGATQ 350
Cdd:PRK10441  325 LV--RRKTRGGAL 335
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
75-339 2.82e-25

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 104.02  E-value: 2.82e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287  75 RVPRILLAAIVGAGLALCGAALQALFRNPLVSPRVLGVSSGAALGGALTL-LIGGGATVLFAATFSSALFALVLVAVISR 153
Cdd:PRK10440   59 RLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMvLFGQDLTAIALAAMAGGIVTSLLVWLLAW 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 154 VAGRTILSIVLAGIVIDALFSAMISLTQYVADPETSLPAiVFWLMGSFSSASWKKVGEHGPVILLAIIILYRLRFRIAVL 233
Cdd:PRK10440  139 RNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTA-GLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLL 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891598287 234 SMGDEEARSFGVNVGFSRWFVFSVISVIIGGCVAVSGVIGWVGLVIPHAARLLVGEGhRRFHGTAALLGASFMVVIDTLA 313
Cdd:PRK10440  218 EMGDDTACALGVSVERSRLLLMLVAVVLTAAATALAGPISFIALVAPHIARRLSGTA-RWGLTQAALCGALLLLAADLCA 296

                         250       260
                  ....*....|....*....|....*..
gi 1891598287 314 RAIISA-ELPLGILTAVIGAPVFIYLL 339
Cdd:PRK10440  297 QQLFMPyQLPVGVVTVSLGGIYLIVLL 323
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH