NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1891019322|gb|QNE85796|]
View 

NADH dehydrogenase subunit 3 [Musca autumnalis]

Protein Classification

NADH dehydrogenase subunit 3( domain architecture ID 10009596)

NADH dehydrogenase subunit 3 is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND3 MTH00161
NADH dehydrogenase subunit 3; Provisional
 19-115 7.07e-32

NADH dehydrogenase subunit 3; Provisional


:

Pssm-ID: 177217 [Multi-domain]  Cd Length: 113  Bit Score: 108.33  E-value: 7.07e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891019322  19 MLLASLLSKKTIVDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPIILIIKFSNLMYWTITSIIFIL 98
Cdd:MTH00161   17 MILASLLSKKSIMDREKSSPFECGFDPKSSARLPFSLRFFLIAIIFLIFDVEIALLLPMIFIFKTSNMMSWLITSSFFIL 96

                          90
                  ....*....|....*..
gi 1891019322  99 ILLLGLYHEWNQGMLNW 115
Cdd:MTH00161   97 ILLLGLYYEWNQGALEW 113
 
Name Accession Description Interval E-value
ND3 MTH00161
NADH dehydrogenase subunit 3; Provisional
 19-115 7.07e-32

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177217 [Multi-domain]  Cd Length: 113  Bit Score: 108.33  E-value: 7.07e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891019322  19 MLLASLLSKKTIVDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPIILIIKFSNLMYWTITSIIFIL 98
Cdd:MTH00161   17 MILASLLSKKSIMDREKSSPFECGFDPKSSARLPFSLRFFLIAIIFLIFDVEIALLLPMIFIFKTSNMMSWLITSSFFIL 96

                          90
                  ....*....|....*..
gi 1891019322  99 ILLLGLYHEWNQGMLNW 115
Cdd:MTH00161   97 ILLLGLYYEWNQGALEW 113
Oxidored_q4 pfam00507
NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;
19-70 3.06e-16

NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;


Pssm-ID: 459838 [Multi-domain]  Cd Length: 94  Bit Score: 67.83  E-value: 3.06e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1891019322  19 MLLASLLSKKTIvDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVE 70
Cdd:pfam00507   1 LLLSRLLGPKRP-NPEKLSPYECGFDPVGDARLRFSVRFYLVAILFLIFDVE 51
NuoA COG0838
NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH: ...
 19-70 3.10e-13

NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 3 (chain A) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440600 [Multi-domain]  Cd Length: 117  Bit Score: 60.91  E-value: 3.10e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1891019322  19 MLLASLLSKKTiVDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVE 70
Cdd:COG0838    23 LLLSRLLGPKR-PNPEKLSPYECGIEPVGDARIRFSVRYYLVALLFVIFDVE 73
 
Name Accession Description Interval E-value
ND3 MTH00161
NADH dehydrogenase subunit 3; Provisional
 19-115 7.07e-32

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177217 [Multi-domain]  Cd Length: 113  Bit Score: 108.33  E-value: 7.07e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891019322  19 MLLASLLSKKTIVDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPIILIIKFSNLMYWTITSIIFIL 98
Cdd:MTH00161   17 MILASLLSKKSIMDREKSSPFECGFDPKSSARLPFSLRFFLIAIIFLIFDVEIALLLPMIFIFKTSNMMSWLITSSFFIL 96

                          90
                  ....*....|....*..
gi 1891019322  99 ILLLGLYHEWNQGMLNW 115
Cdd:MTH00161   97 ILLLGLYYEWNQGALEW 113
ND3 MTH00148
NADH dehydrogenase subunit 3; Provisional
 19-116 1.76e-24

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214433 [Multi-domain]  Cd Length: 117  Bit Score: 89.53  E-value: 1.76e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891019322  19 MLLASLLSKKTIVDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPIILIIKFSNLMYWTITSIIFIL 98
Cdd:MTH00148   19 LLLGLVLSKRSYSDREKSSPFECGFDPISSARSPFSLRFFLLAILFLVFDVEIVLLFPVLQSLGSSFSVWSLTSLFIFLL 98

                          90
                  ....*....|....*...
gi 1891019322  99 ILLLGLYHEWNQGMLNWS 116
Cdd:MTH00148   99 ILILGLFHEWNEGSLDWV 116
ND3 MTH00202
NADH dehydrogenase subunit 3; Provisional
 20-115 2.06e-22

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214455 [Multi-domain]  Cd Length: 117  Bit Score: 84.27  E-value: 2.06e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891019322  20 LLASLLSKKTIVDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPIILIIKFSNLMYWTITSIIFILI 99
Cdd:MTH00202   20 LVSWMLSFRSLMDREKSSPFECGFDPKESARLPFSMRFFLLAVIFLVFDIEIALLLPLPLVLKSSWSKGGLLGGTIFLLI 99

                          90
                  ....*....|....*.
gi 1891019322 100 LLLGLYHEWNQGMLNW 115
Cdd:MTH00202  100 LIGGLIHEWKEGSLDW 115
ND3 MTH00012
NADH dehydrogenase subunit 3; Validated
 19-116 5.84e-20

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 164588 [Multi-domain]  Cd Length: 117  Bit Score: 78.36  E-value: 5.84e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891019322  19 MLLASLLSKKTIVDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPIILIIKFSNLMYWTITSIIFIL 98
Cdd:MTH00012   19 LGAAWVLAARSTADREKTSPFECGFDPHKTARIPFSLRFFLLAIIFIVFDIEIVLLMPVPTILMTSTSKTVVYTSILFLL 98

                          90
                  ....*....|....*...
gi 1891019322  99 ILLLGLYHEWNQGMLNWS 116
Cdd:MTH00012   99 ILVIGLIHEWREGSLDWS 116
ND3 MTH00136
NADH dehydrogenase subunit 3; Provisional
 32-70 9.57e-18

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177194 [Multi-domain]  Cd Length: 116  Bit Score: 72.64  E-value: 9.57e-18
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1891019322  32 DREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVE 70
Cdd:MTH00136   31 DHEKLSPYECGFDPLGSARLPFSLRFFLVAILFLLFDLE 69
ND3 MTH00069
NADH dehydrogenase subunit 3; Provisional
 32-70 2.70e-16

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177141 [Multi-domain]  Cd Length: 114  Bit Score: 68.87  E-value: 2.70e-16
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1891019322  32 DREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVE 70
Cdd:MTH00069   29 DSEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLE 67
Oxidored_q4 pfam00507
NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;
19-70 3.06e-16

NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;


Pssm-ID: 459838 [Multi-domain]  Cd Length: 94  Bit Score: 67.83  E-value: 3.06e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1891019322  19 MLLASLLSKKTIvDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVE 70
Cdd:pfam00507   1 LLLSRLLGPKRP-NPEKLSPYECGFDPVGDARLRFSVRFYLVAILFLIFDVE 51
ND3 MTH00106
NADH dehydrogenase subunit 3; Provisional
 34-70 7.60e-16

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177168 [Multi-domain]  Cd Length: 115  Bit Score: 67.66  E-value: 7.60e-16
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1891019322  34 EKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVE 70
Cdd:MTH00106   32 EKASPYECGFDPMGSARLPFSMKFFLVAITFLLFDLE 68
ND3 MTH00042
NADH dehydrogenase subunit 3; Validated
 32-117 9.19e-16

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 177117 [Multi-domain]  Cd Length: 116  Bit Score: 67.31  E-value: 9.19e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891019322  32 DREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPIILIIKFSNLMYWTITSIIFILILLLGLYHEWNQG 111
Cdd:MTH00042   31 DLEKSSPYECGFDPLNSARLPFSFRFFLVAILFLLFDLEIALLFPLPPATLITNPSTLLPISLIFLIILTIGLVYEWVNG 110


                  ....*.
gi 1891019322 112 MLNWSN 117
Cdd:MTH00042  111 GLEWAE 116
ND3 MTH00113
NADH dehydrogenase subunit 3; Provisional
 32-115 2.46e-15

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177175 [Multi-domain]  Cd Length: 114  Bit Score: 66.44  E-value: 2.46e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891019322  32 DREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPIILIIKFSNLMYWTITSIIFILILLLGLYHEWNQG 111
Cdd:MTH00113   30 DNEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAINLTTPTTTLTWATIILTLLTLGLIYEWLQG 109


                  ....
gi 1891019322 112 MLNW 115
Cdd:MTH00113  110 GLEW 113
ND3 MTH00203
NADH dehydrogenase subunit 3; Provisional
 19-115 4.91e-14

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214456 [Multi-domain]  Cd Length: 112  Bit Score: 62.99  E-value: 4.91e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891019322  19 MLLASLLSKKTIVDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPIILIIKFSNLMYWtiTSIIFIL 98
Cdd:MTH00203   18 LLFIAFWLPKVNPDGEKLSPYECGFDPLGSARLPFSLQFFLVALSFLLFDLEIALLLPLPWSNQLSSLSLL--LAFLFLI 95

                          90
                  ....*....|....*..
gi 1891019322  99 ILLLGLYHEWNQGMLNW 115
Cdd:MTH00203   96 LLTLGLIYEWLQGGLEW 112
NuoA COG0838
NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH: ...
 19-70 3.10e-13

NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 3 (chain A) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440600 [Multi-domain]  Cd Length: 117  Bit Score: 60.91  E-value: 3.10e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1891019322  19 MLLASLLSKKTiVDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVE 70
Cdd:COG0838    23 LLLSRLLGPKR-PNPEKLSPYECGIEPVGDARIRFSVRYYLVALLFVIFDVE 73
ND3 MTH00055
NADH dehydrogenase subunit 3; Provisional
 32-70 5.00e-12

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177128 [Multi-domain]  Cd Length: 118  Bit Score: 57.80  E-value: 5.00e-12
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1891019322  32 DREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVE 70
Cdd:MTH00055   35 DSEKVSVYECGFDPFESSRIPFSVRFFLVGILFLIFDLE 73
PRK06602 PRK06602
NADH:ubiquinone oxidoreductase subunit A; Validated
 19-70 8.83e-12

NADH:ubiquinone oxidoreductase subunit A; Validated


Pssm-ID: 180638 [Multi-domain]  Cd Length: 121  Bit Score: 57.18  E-value: 8.83e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1891019322  19 MLLASLLSKKTiVDREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVE 70
Cdd:PRK06602   26 LVAGKLLGPRA-PDREKNSPYESGFEAFGDARMKFDVRFYLVAILFVIFDLE 76
ND3 MTH00018
NADH dehydrogenase subunit 3; Validated
 32-70 8.11e-11

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 164592 [Multi-domain]  Cd Length: 113  Bit Score: 54.68  E-value: 8.11e-11
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1891019322  32 DREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVE 70
Cdd:MTH00018   30 DREKVSAYECGFDPFGFPGRPFSIRFFLIGILFLIFDLE 68
ND3 MTH00030
NADH dehydrogenase subunit 3; Provisional
 32-115 2.79e-07

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 164603 [Multi-domain]  Cd Length: 123  Bit Score: 45.69  E-value: 2.79e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891019322  32 DREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVEIALILPIILIIKFSNLMYWTITSIIFILILLLGLYhEWNQG 111
Cdd:MTH00030   40 DSEKSSIYECGFDPFGKIRTPFTIKFVLVGILFMIFDIEISFLFPWSIVFNQLNLFSFWIVYTFLIVLAIGLAY-EWIKG 118


                  ....
gi 1891019322 112 MLNW 115
Cdd:MTH00030  119 GLEW 122
PRK07756 PRK07756
NADH-quinone oxidoreductase subunit A;
32-70 6.18e-04

NADH-quinone oxidoreductase subunit A;


Pssm-ID: 169084 [Multi-domain]  Cd Length: 122  Bit Score: 36.64  E-value: 6.18e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1891019322  32 DREKASPFECGFDPKSSSRLPFSLRFFLITIIFLIFDVE 70
Cdd:PRK07756   39 SAAKATTYESGIEPFHDANIRFHARYYIFALLFVIFDVE 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH