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Conserved domains on  [gi|189095266|ref|NP_001121163|]
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blood group Rh(D) polypeptide isoform 2 [Homo sapiens]

Protein Classification

ammonium transporter family protein( domain architecture ID 518)

ammonium transporter family protein similar to Dictyostelium discoideum ammonium transporter 3 that mediates the import of ammonium in prespore cells

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ammonium_transp super family cl03012
Ammonium Transporter Family;
18-312 7.19e-54

Ammonium Transporter Family;


The actual alignment was detected with superfamily member pfam00909:

Pssm-ID: 445985  Cd Length: 399  Bit Score: 180.95  E-value: 7.19e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095266   18 LTLEAALILLFYF---FTHYDASLEDQKGLVA-SYQVGQDL--TVMAAIGLGFLTSSFRRHSWSSVAFNLFMLALGVQWA 91
Cdd:pfam00909   1 AFILLSAALVIFMqpgFALLESGLVRSKNVLNiLYKNFQDVaiGVLAYWLFGYSLAFGKRYGFSGFIGNLGVSAAGIQWG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095266   92 ILLDG--FLSQFPSGKVVITLFSIRLATMSALSVLISVDAVLGKVNLAQLVVMVLVEVTALGNLRMVIsnifntDYHMNM 169
Cdd:pfam00909  81 TLPDGlfFLFQMMFAATAITIVSGAVAERIKFSAYLLFSALLGTLVYPPVAHWVWGEGGWLAKLGVLV------DFAGST 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095266  170 MhIYVFAAYFGLSVAWCLPKPLPEGTEDKDQTATIPSLSAMLGALFLWMFWPSFN--SALLRSPIERKNAVFNTYYAVAV 247
Cdd:pfam00909 155 V-VHIFGGYAGLAAALVLGPRIGRFTGKNEAITPHNLPFAVLGTFLLWFGWFGFNagSALTANGRARAIAAVNTNLAAAG 233

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 189095266  248 SVVTAISGSSLAHpqGKISKTYVHSAVLAGGVAVGTSCHLIpSPWLAMVLGLVAGLISVGGAKYL 312
Cdd:pfam00909 234 GGLTALLISRLKT--GKPNMLGLANGALAGLVAITPACGVV-TPWGALIIGLIAGVLSVLGYKFL 295
 
Name Accession Description Interval E-value
Ammonium_transp pfam00909
Ammonium Transporter Family;
18-312 7.19e-54

Ammonium Transporter Family;


Pssm-ID: 395729  Cd Length: 399  Bit Score: 180.95  E-value: 7.19e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095266   18 LTLEAALILLFYF---FTHYDASLEDQKGLVA-SYQVGQDL--TVMAAIGLGFLTSSFRRHSWSSVAFNLFMLALGVQWA 91
Cdd:pfam00909   1 AFILLSAALVIFMqpgFALLESGLVRSKNVLNiLYKNFQDVaiGVLAYWLFGYSLAFGKRYGFSGFIGNLGVSAAGIQWG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095266   92 ILLDG--FLSQFPSGKVVITLFSIRLATMSALSVLISVDAVLGKVNLAQLVVMVLVEVTALGNLRMVIsnifntDYHMNM 169
Cdd:pfam00909  81 TLPDGlfFLFQMMFAATAITIVSGAVAERIKFSAYLLFSALLGTLVYPPVAHWVWGEGGWLAKLGVLV------DFAGST 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095266  170 MhIYVFAAYFGLSVAWCLPKPLPEGTEDKDQTATIPSLSAMLGALFLWMFWPSFN--SALLRSPIERKNAVFNTYYAVAV 247
Cdd:pfam00909 155 V-VHIFGGYAGLAAALVLGPRIGRFTGKNEAITPHNLPFAVLGTFLLWFGWFGFNagSALTANGRARAIAAVNTNLAAAG 233

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 189095266  248 SVVTAISGSSLAHpqGKISKTYVHSAVLAGGVAVGTSCHLIpSPWLAMVLGLVAGLISVGGAKYL 312
Cdd:pfam00909 234 GGLTALLISRLKT--GKPNMLGLANGALAGLVAITPACGVV-TPWGALIIGLIAGVLSVLGYKFL 295
AmtB COG0004
Ammonia channel protein AmtB [Inorganic ion transport and metabolism];
209-312 4.37e-11

Ammonia channel protein AmtB [Inorganic ion transport and metabolism];


Pssm-ID: 439775  Cd Length: 413  Bit Score: 63.21  E-value: 4.37e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095266 209 AMLGALFLWMFWPSFN--SALLRSPIErKNAVFNTYYAVAVSVVTAISGSSLAHpqGKISKTYVHSAVLAGGVAVGTSCH 286
Cdd:COG0004  206 AALGAFLLWFGWFGFNagSALAANGLA-GLAFVNTNLAAAAGALAWLLVEWLRK--GKPDLLGAANGALAGLVAITPAAG 282

                         90       100
                 ....*....|....*....|....*.
gi 189095266 287 LIpSPWLAMVLGLVAGLISVGGAKYL 312
Cdd:COG0004  283 FV-SPLGALVIGLIAGVICVFAVTFL 307
 
Name Accession Description Interval E-value
Ammonium_transp pfam00909
Ammonium Transporter Family;
18-312 7.19e-54

Ammonium Transporter Family;


Pssm-ID: 395729  Cd Length: 399  Bit Score: 180.95  E-value: 7.19e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095266   18 LTLEAALILLFYF---FTHYDASLEDQKGLVA-SYQVGQDL--TVMAAIGLGFLTSSFRRHSWSSVAFNLFMLALGVQWA 91
Cdd:pfam00909   1 AFILLSAALVIFMqpgFALLESGLVRSKNVLNiLYKNFQDVaiGVLAYWLFGYSLAFGKRYGFSGFIGNLGVSAAGIQWG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095266   92 ILLDG--FLSQFPSGKVVITLFSIRLATMSALSVLISVDAVLGKVNLAQLVVMVLVEVTALGNLRMVIsnifntDYHMNM 169
Cdd:pfam00909  81 TLPDGlfFLFQMMFAATAITIVSGAVAERIKFSAYLLFSALLGTLVYPPVAHWVWGEGGWLAKLGVLV------DFAGST 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095266  170 MhIYVFAAYFGLSVAWCLPKPLPEGTEDKDQTATIPSLSAMLGALFLWMFWPSFN--SALLRSPIERKNAVFNTYYAVAV 247
Cdd:pfam00909 155 V-VHIFGGYAGLAAALVLGPRIGRFTGKNEAITPHNLPFAVLGTFLLWFGWFGFNagSALTANGRARAIAAVNTNLAAAG 233

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 189095266  248 SVVTAISGSSLAHpqGKISKTYVHSAVLAGGVAVGTSCHLIpSPWLAMVLGLVAGLISVGGAKYL 312
Cdd:pfam00909 234 GGLTALLISRLKT--GKPNMLGLANGALAGLVAITPACGVV-TPWGALIIGLIAGVLSVLGYKFL 295
AmtB COG0004
Ammonia channel protein AmtB [Inorganic ion transport and metabolism];
209-312 4.37e-11

Ammonia channel protein AmtB [Inorganic ion transport and metabolism];


Pssm-ID: 439775  Cd Length: 413  Bit Score: 63.21  E-value: 4.37e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095266 209 AMLGALFLWMFWPSFN--SALLRSPIErKNAVFNTYYAVAVSVVTAISGSSLAHpqGKISKTYVHSAVLAGGVAVGTSCH 286
Cdd:COG0004  206 AALGAFLLWFGWFGFNagSALAANGLA-GLAFVNTNLAAAAGALAWLLVEWLRK--GKPDLLGAANGALAGLVAITPAAG 282

                         90       100
                 ....*....|....*....|....*.
gi 189095266 287 LIpSPWLAMVLGLVAGLISVGGAKYL 312
Cdd:COG0004  283 FV-SPLGALVIGLIAGVICVFAVTFL 307
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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