NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1883232606|gb|QMQ21105|]
View 

conjugative transfer relaxase/helicase TraI (plasmid) [Escherichia coli]

Protein Classification

conjugative transfer relaxase/helicase TraI( domain architecture ID 11486805)

conjugative transfer relaxase/helicase TraI is the central catalytic component of the multiprotein relaxosome complex responsible for conjugative DNA transfer (CDT) between bacterial cells

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PRK13709 PRK13709
conjugal transfer nickase/helicase TraI; Provisional
2-1751 0e+00

conjugal transfer nickase/helicase TraI; Provisional


:

Pssm-ID: 237478 [Multi-domain]  Cd Length: 1747  Bit Score: 3085.93  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606    2 MSIAQVRSAGSAGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNRHRPGYD 81
Cdd:PRK13709     1 MSIAQVKSAGSAGNYYTDKDNYYVLGSMGERWAGEGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYD 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   82 LTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAV 161
Cdd:PRK13709    81 LTFSAPKSVSMMAMLGGDKRLIEAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHAV 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  162 VANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVPVEAFSGRSQAI 241
Cdd:PRK13709   161 VANVTQHNGKWKTLSSDKVGKTGFIENVYANQIAFGKIYREALKEDVEALGYETEVVGKHGMWEMKGVPVEAFSSRSQEI 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  242 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAETRTQAPGAVSQEGPDVQQAVT 321
Cdd:PRK13709   241 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYREAADQRAEIRTQAPGPASQDGPDIQQAVT 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  322 QAIAGLSERKVQFTYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 401
Cdd:PRK13709   321 QAIAGLSDRKVQFTYTDLLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  402 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMVREQGREVQIIAADRRSQMNLKQDER 481
Cdd:PRK13709   401 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQILAADRRSQMNLKQDER 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  482 LSGELITGRRQLLEGMAFTPGSTVIVDQGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQ 561
Cdd:PRK13709   481 LSGELITGRRQLQEGMAFTPGSTLIVDQAEKLSLKETLTLLDGAARHNVQVLILDSGQRTGTGSALMVLKDAGVNTYRWQ 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  562 GGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVLGHQEVTMTALSPVWLDS 641
Cdd:PRK13709   561 GGEQRPATVISEPDKNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTGLIRSALKTQGVLGRPEVTITALSPVWLDS 640
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  642 RSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVT 721
Cdd:PRK13709   641 KSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVKISSLDSSWSLFRPEKMPVADGERLRVL 720
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  722 GKISGLRVSGGDRLQVASVSEDAMTVVVPGRAEPASLPVSDSPFTALKLENGWVETPGHSVSDSAKVFASVTQMAMDNAT 801
Cdd:PRK13709   721 GKIPGLRLKGGDRLQVTSVSEDGLTVVVPGRAEPATLPVDDSPFTALKLEHGWVETPGHSVSDSATVFASVTQRAMDNAT 800
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  802 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETSLETAISHQKSVLHTPAQQAIHLALPVVESKNLA 881
Cdd:PRK13709   801 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETDLETAISLQKAGLHTPAQQAIHLALPVLESKNLA 880
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  882 FSQVDLLTEAKSFAAEGTSFTELGGEIDAQIKRGDLLHVDVAKGYGTDLLVSRASYEAEKSILRHILEGKEAVTPLMERV 961
Cdd:PRK13709   881 FSMVDLLTEAKSFAAEGTSFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERV 960
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  962 PGELMEMLTSGQRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1041
Cdd:PRK13709   961 PGELMEGLTSGQRAATRMILESTDRFTVVQGYAGVGKTTQFRAVMSAVNTLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1040
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1042 TLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAA 1121
Cdd:PRK13709  1041 TLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVSSGDTDQLQAIAPGQPFRLMQTRSAA 1120
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1122 DVAIMKEIVRQTPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLkgeAF 1201
Cdd:PRK13709  1121 DVAIMKEIVRQTPELREAVYSLINRDVERALSGIESVKPSQVPRQEGAWAPESSVTEFSHPQEAKLAEAQQKAML---AF 1197
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1202 PDVPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWE 1281
Cdd:PRK13709  1198 PDVPMTLYEAIVRDYTGRTPEAREQTLIITHLNEDRRVLNSMIHDAREKAGELGKEQVTVPVLDTANIRDGELRRLSTWE 1277
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1282 THRDALALVDNVYHRIAGISKDDGLITLQDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1361
Cdd:PRK13709  1278 AHRGALALVDNVYHRIAGIDKDDGLITLRDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1357
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1362 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKLMAGFESAYVALSRMKQ 1441
Cdd:PRK13709  1358 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETYAIALEGTEGGRKQMAGFESAYVALSRMKQ 1437
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1442 HVQVYTDNRQGWTDTINNAVQKGTAHDVFEPKPDREVMNAERLFSTARELRDVAAGRAVLRQAGLAGGDSPARFIAPGRK 1521
Cdd:PRK13709  1438 HVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKPDREVMNAERLFSTARELRDTAAGRAVLRQAGLAGGDSPARFIAPGRK 1517
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1522 YPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1601
Cdd:PRK13709  1518 YPQPHVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSEDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1597
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1602 GVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1681
Cdd:PRK13709  1598 GVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1677
                         1690      1700      1710      1720      1730      1740      1750
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1682 GRTEQAVREIAGQERERAVTSEREAALPESVLREPQREREAVREVVRENLLQERLQQMERDMVRDLQKEK 1751
Cdd:PRK13709  1678 GKTEQAVRDIAGQERDRAAISEREAALPESVLREPQREREAVREVARENLLRERLQQMERDMVRDLQKEK 1747
 
Name Accession Description Interval E-value
PRK13709 PRK13709
conjugal transfer nickase/helicase TraI; Provisional
2-1751 0e+00

conjugal transfer nickase/helicase TraI; Provisional


Pssm-ID: 237478 [Multi-domain]  Cd Length: 1747  Bit Score: 3085.93  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606    2 MSIAQVRSAGSAGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNRHRPGYD 81
Cdd:PRK13709     1 MSIAQVKSAGSAGNYYTDKDNYYVLGSMGERWAGEGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYD 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   82 LTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAV 161
Cdd:PRK13709    81 LTFSAPKSVSMMAMLGGDKRLIEAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHAV 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  162 VANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVPVEAFSGRSQAI 241
Cdd:PRK13709   161 VANVTQHNGKWKTLSSDKVGKTGFIENVYANQIAFGKIYREALKEDVEALGYETEVVGKHGMWEMKGVPVEAFSSRSQEI 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  242 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAETRTQAPGAVSQEGPDVQQAVT 321
Cdd:PRK13709   241 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYREAADQRAEIRTQAPGPASQDGPDIQQAVT 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  322 QAIAGLSERKVQFTYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 401
Cdd:PRK13709   321 QAIAGLSDRKVQFTYTDLLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  402 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMVREQGREVQIIAADRRSQMNLKQDER 481
Cdd:PRK13709   401 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQILAADRRSQMNLKQDER 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  482 LSGELITGRRQLLEGMAFTPGSTVIVDQGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQ 561
Cdd:PRK13709   481 LSGELITGRRQLQEGMAFTPGSTLIVDQAEKLSLKETLTLLDGAARHNVQVLILDSGQRTGTGSALMVLKDAGVNTYRWQ 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  562 GGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVLGHQEVTMTALSPVWLDS 641
Cdd:PRK13709   561 GGEQRPATVISEPDKNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTGLIRSALKTQGVLGRPEVTITALSPVWLDS 640
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  642 RSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVT 721
Cdd:PRK13709   641 KSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVKISSLDSSWSLFRPEKMPVADGERLRVL 720
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  722 GKISGLRVSGGDRLQVASVSEDAMTVVVPGRAEPASLPVSDSPFTALKLENGWVETPGHSVSDSAKVFASVTQMAMDNAT 801
Cdd:PRK13709   721 GKIPGLRLKGGDRLQVTSVSEDGLTVVVPGRAEPATLPVDDSPFTALKLEHGWVETPGHSVSDSATVFASVTQRAMDNAT 800
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  802 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETSLETAISHQKSVLHTPAQQAIHLALPVVESKNLA 881
Cdd:PRK13709   801 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETDLETAISLQKAGLHTPAQQAIHLALPVLESKNLA 880
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  882 FSQVDLLTEAKSFAAEGTSFTELGGEIDAQIKRGDLLHVDVAKGYGTDLLVSRASYEAEKSILRHILEGKEAVTPLMERV 961
Cdd:PRK13709   881 FSMVDLLTEAKSFAAEGTSFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERV 960
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  962 PGELMEMLTSGQRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1041
Cdd:PRK13709   961 PGELMEGLTSGQRAATRMILESTDRFTVVQGYAGVGKTTQFRAVMSAVNTLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1040
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1042 TLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAA 1121
Cdd:PRK13709  1041 TLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVSSGDTDQLQAIAPGQPFRLMQTRSAA 1120
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1122 DVAIMKEIVRQTPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLkgeAF 1201
Cdd:PRK13709  1121 DVAIMKEIVRQTPELREAVYSLINRDVERALSGIESVKPSQVPRQEGAWAPESSVTEFSHPQEAKLAEAQQKAML---AF 1197
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1202 PDVPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWE 1281
Cdd:PRK13709  1198 PDVPMTLYEAIVRDYTGRTPEAREQTLIITHLNEDRRVLNSMIHDAREKAGELGKEQVTVPVLDTANIRDGELRRLSTWE 1277
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1282 THRDALALVDNVYHRIAGISKDDGLITLQDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1361
Cdd:PRK13709  1278 AHRGALALVDNVYHRIAGIDKDDGLITLRDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1357
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1362 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKLMAGFESAYVALSRMKQ 1441
Cdd:PRK13709  1358 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETYAIALEGTEGGRKQMAGFESAYVALSRMKQ 1437
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1442 HVQVYTDNRQGWTDTINNAVQKGTAHDVFEPKPDREVMNAERLFSTARELRDVAAGRAVLRQAGLAGGDSPARFIAPGRK 1521
Cdd:PRK13709  1438 HVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKPDREVMNAERLFSTARELRDTAAGRAVLRQAGLAGGDSPARFIAPGRK 1517
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1522 YPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1601
Cdd:PRK13709  1518 YPQPHVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSEDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1597
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1602 GVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1681
Cdd:PRK13709  1598 GVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1677
                         1690      1700      1710      1720      1730      1740      1750
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1682 GRTEQAVREIAGQERERAVTSEREAALPESVLREPQREREAVREVVRENLLQERLQQMERDMVRDLQKEK 1751
Cdd:PRK13709  1678 GKTEQAVRDIAGQERDRAAISEREAALPESVLREPQREREAVREVARENLLRERLQQMERDMVRDLQKEK 1747
TraI_TIGR TIGR02760
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ...
1-1756 0e+00

conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.


Pssm-ID: 274285 [Multi-domain]  Cd Length: 1960  Bit Score: 1982.45  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606    1 MMSIAQVRSAGSAGNYYTDKDNYYVLGSM---GERWAGRGAEQLGLQG-SVDKDVFTRLLEGRLPDGADLSRMQDGSNRH 76
Cdd:TIGR02760    1 MMSISPLRSAGDAAAYYLDEDNYYLKDSKslnNTRWLGKGAEQLGLLGkPVEKEQFEALLSGTLPDGTQLGRIDKGGIHH 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   77 RPGYDLTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQ 155
Cdd:TIGR02760   81 RPGFDLTFSAPKSVSILALVGGDKRLIEAHDKAVKIAVSEMEKdAAQARQTVDGKTEFINTRNLVFAMFRHKTSRENDPQ 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  156 LHTHAVVANVTQ-HNGEWKTLSSDKVGKTGFI----ENVYANQIAFGRLYREKLKEQVEALGYETEVVGKhGMWEMPGVP 230
Cdd:TIGR02760  161 LHTHAVVQNMTHdSDGKWRSLASDMKGQKGVIegfrERIYNHQIYYGLLYRSKLAKKVEELGYQTASVGK-GQFEIQGVP 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  231 ---VEAFSGRSQAIREAVGEDA--SLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAETRTQA 305
Cdd:TIGR02760  240 eqvLTAFSKRRQQIDELVDEKGwsSAKARDIAALDTRKDKTYIDDETLMEKWQQECKDMGFDPHALVASSYKPENIVARF 319
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  306 PGAVSQegpDVQQAVTQAIAGLSERKVQFTYTDVLARTVGILPPENGVIER--ARAGIDEAISREQLIPLDREKGLFTSG 383
Cdd:TIGR02760  320 YGPSQI---DAQHAVEVAIAHLSQYSTQFEYEKLIEEAAKYFTAGNKIIDEidIKKAIDELIANGQLIPLFTQKGLFTTQ 396
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  384 IHVLDELSVRALSRDIMKQNRVTVHPEKSV--PRTAGYSDAVSVLAQDRPSLAIVSGQGGAaGQRERVAELVMMVREQGR 461
Cdd:TIGR02760  397 TMLTNEKELIARTEGGKGALRVIVSKQKLSefALSPSNKDAVSTLFTSTKRFIIINGFGGT-GSTEIAQLLLHLASEQGY 475
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  462 EVQIIAADRRSQMNLKQD-ERLSGELITGRRQLLEGM-------------AFTPGSTVIVDQGEKLSLKETLTLLDGAAR 527
Cdd:TIGR02760  476 EIQIITAGSLSAQELRQKiPRLASTFITWVKNLFNDDqdhtvqglldkssPFSNKDIFVVDEANKLSNNELLKLIDKAEQ 555
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  528 HNVQ-VLITDSGQRTG--TGSALMAMKDAGVNTYRWQGGEQRPATI-ISEPDRNVRYARLAGDFAASVKAGEESVAQVSG 603
Cdd:TIGR02760  556 HNSKlILLNDSAQRQGmsAGSAIDLLKEGGVTTYAWVDTKQQKASVeISEAVDKLRVDYIASAWLDLTPDRQNSQVLATT 635
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  604 VREQAILTQAIRSELKTQGVLGHQEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTL 683
Cdd:TIGR02760  636 HREQQDLTQIIRNALKQEGQLSRQEVTVPTLKPVNLTGIQRRNAAHYKQGMVIRFWQKGKIPHDDYVVTNVNKHNNTLTL 715
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  684 RDAQGETQVVRISSL---DSSWSLFRPEKMPVADGERLRVTGKISGLRVSGGDRLQVASVSEDAMTVV-VPGRaepaSLP 759
Cdd:TIGR02760  716 KDAQGKTQKFKPSSLkdlERPFSVYRPEQLEVAAGERLQVTGNHFHSRVRNGELLTVSSINNEGITLItEDGQ----TLH 791
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  760 VSDSPFTALKLENGWVETPGHSVSDSAKVFASVTQMAMDNATLNGLARSGRDVRLYSSLDET--RTAEKLARHPSFTVVS 837
Cdd:TIGR02760  792 LPHGALEDAHLDYGYVLTPYHTQPDDAKVFLGVKQYALSKALLNSLNRSASRVDLFTDLDEKaqRYLEKTRGIPSAIVVV 871
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  838 EQIKARAGE-------TSLETAISHQKSVLHTPAQQ-----AIHLALPVVESKNLAFSQVDLLTEAKSFAAEGTSFTELG 905
Cdd:TIGR02760  872 DQKQHLPDAvttnntdKSLEMDISDTLHALEAKAKDgknsiALQYALEKVSEKEAAFKQKELVTEAYVFAFEETGFAIKA 951
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  906 GEIDAQIKRGDLLHVDVAKGYGT-DLLVSRASYEAEKSILRHILEGKEAVTPLMERVPG----ELMEMLTSGQRAATRMI 980
Cdd:TIGR02760  952 AEIAAALKNRPKLYRLLSAEYGDgTRWTTRAALRTETSILLHILPGKETVTPLATRAQVflnlELLERLTHGQKQAIHLI 1031
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  981 LETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVDAQTLASFLHDTQLQQRSGEtp 1060
Cdd:TIGR02760 1032 ISTKDRFVAVQGLAGVGKTTMLESRYKPVLQAFESEQLQVIGLAPTHEAVGELKSAGVQAQTLDSFLTDISLYRNSGG-- 1109
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1061 DFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKEIVRQ--TPELRE 1138
Cdd:TIGR02760 1110 DFRNTLFILDESSMVSNFQLTHATELVQKSGSRAVSLGDIAQLQSLAAGKPFELAITFDIIDTAIMKEIVRQnnSAELKA 1189
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1139 AVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHsQEAKLAEAQQKAMLKGEAFPDVPMTLYEAIVRDYTG 1218
Cdd:TIGR02760 1190 AHNSLDKRSNPKALELLKNQNPLQHELMQNAAMPEIASDEQGL-QKHDLAKLAVNTEKPKKAQPDATVTLYREIVKDYLS 1268
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1219 RTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWEThRDALALVDNVYHRIA 1298
Cdd:TIGR02760 1269 RTPEFRENTLIIAHTNNDRTGIYPFIREGLIKQKELSKQQVTVPRLRSVNISSPELKTMMPFEK-GAVLRLKKDAYLTIA 1347
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1299 GISKDDGLITLQDAE-GNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSVWTVTAV-SGDSVTLSD 1376
Cdd:TIGR02760 1348 DIDREHGKLTVADIKtGSERDILPRQLDHTFTSLYSDSELPLAKGDKIRLRATDKNRGIKANEVYTVTQVvNGLSVQLSK 1427
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1377 GQQTRVIRPGQERaEQHIDLAYAITAHGAQGASETFAIALegtEGNRKLMAGFESAYVALSRMKQHVQVYTDNRQGWT-- 1454
Cdd:TIGR02760 1428 VKNSLSLKPIQAK-DKHWDYAYTRTADSAQGATYTFVIAL---IKGRLALTNYRSAYIDLTRASHHVELYTDNKEGTVks 1503
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1455 ---------------------------------------------------DTINNAV---------------------- 1461
Cdd:TIGR02760 1504 wkqreanktsaveteedyrpkqstqfnnraqpheepkyqqkngplkiqsaaEIINEALpayteslaktllgepntqksrr 1583
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1462 -----------------------------QKGTAHDVFEPKPD---REVMN----------------------------- 1480
Cdd:TIGR02760 1584 drytfgakgglkvsltgkyrglwhdfstgEKGTLIQLIEAKKGlsfKEALNqaasllgipqhyqlsinikapqlsntepq 1663
                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1481 --------AERLFSTARELRDVAAGRAVLRQAGLAGGDSPARFIAP-----GRKYPQPYVALPAFDRNGKSAGIWLNPLT 1547
Cdd:TIGR02760 1664 klnqlekrAKSLFQGSQELKGTLAEKYLKQHRGLASIDNDDIRFHPtvyssDKKNKHPALIAAARNEKGEITGIQITYLD 1743
                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1548 TDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGE-SLLADNMQDGVRIARDNPDSGVVVRIAGegrpwnpgaitggrvwg 1626
Cdd:TIGR02760 1744 KDDANKDKDMDNNKRVKGSISGQFVVINKGMQGDrSYIAEGIETGLSIALANPKATVVIAVGG----------------- 1806
                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1627 dipDNSVQPGAGNGEPVTAEVLAQRQAEEAIrreTERRADEIVRKMAENK-----------PDLPDGRTEQAVREIAGQE 1695
Cdd:TIGR02760 1807 ---KNNLSPIIPKFIPKNVVIVLDNDGEEAK---SQRAIEKIINKFKQDNisarivfpddwNDIGEEELQKQLMRAISSI 1880
                         1930      1940      1950      1960      1970      1980
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1883232606 1696 RERAVTSEREAALPESVLREPQREREAVREVVRENLLQERLQQM-------ERDMVRDLQKEKTLGGD 1756
Cdd:TIGR02760 1881 EDKDIEIPKAIADFESVLKMPNSDIISIIDNARTEREKSDLEQIvanehksQQALERDLNKEFTPDKR 1948
MobF NF041492
MobF family relaxase;
1-281 6.19e-112

MobF family relaxase;


Pssm-ID: 469380 [Multi-domain]  Cd Length: 288  Bit Score: 357.00  E-value: 6.19e-112
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606    1 MMSIAQVRSAGSAGNYYTDKD--NYYVLG--SMGERWAGRGAEQLGL-QGSVDKDVFTRLLEGRLPDGADLSRMQDGSNR 75
Cdd:NF041492     1 MLSIARIGSAGGAARYYTEKDldNYYSEDggTPAGRWFGKGAEALGLsGGAVDGERFKALLDGRLPDGERLRRRRKGAGR 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   76 HRPGYDLTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVR-QVEALASTRVMTDGQSETVL--TGNLVMALFNHDTSRDQ 152
Cdd:NF041492    81 HRPGYDLTFSAPKSVSLLALVGGDKRLIEAHDEAVKEALEyLEERLAQTRVTVDGKGRTSLekTGNLVAALFRHDTSRAG 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  153 EPQLHTHAVVANVTQH-NGEWKTLSSdkvgktgfiENVYANQIAFGRLYREKLKEQVEALGYETEVVgKHGMWEMPGVP- 230
Cdd:NF041492   161 DPQLHTHAVVMNMTQRpDGKWRSLDN---------EELYKNQKALGAIYQAELAEELQALGYEIRET-KNGQFEIAGVPr 230
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1883232606  231 --VEAFSGRSQAIREAVGED----ASLKSRDVAALDTRKSKQ-HVDPEVRMAEWMQTL 281
Cdd:NF041492   231 eqIEAFSKRSQQIEEWLGENpatlASAALRQIAALDTRKAKEaDVDPEELEAEWREEA 288
TrwC pfam08751
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative ...
10-283 6.52e-97

TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative cell to cell DNA transfer. TrwC binds to the origin of transfer (oriT) and melts the double helix.


Pssm-ID: 430190 [Multi-domain]  Cd Length: 279  Bit Score: 313.78  E-value: 6.52e-97
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   10 AGSAGNYYTDKDNYYVL-GSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGRLPD-GADLSRMQDGSNRHRPGYDLTFSAP 87
Cdd:pfam08751    1 AGDAYAYYTRQDDYYTEgGEPPGRWLGKGAAALGLSGEVTEEQFEALLEGRHPDtGERLGRRRPRGRKHRAGFDLTFSAP 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   88 KSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAVVANVT 166
Cdd:pfam08751   81 KSVSLLAAVGGDERIEAAHRAAVAEALAWLEKhAAQTRVGKDGGVEQVDTGGLVAAAFRHDTSRAGDPQLHTHVVVANVT 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  167 Q-HNGEWKTLSSDKvgktgfienVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVP---VEAFSGRSQAIR 242
Cdd:pfam08751  161 QrEDGKWRALDSRG---------LYKAQVAAGAVYRAELADELRRLGYEIEERGKRGVFEIAGVPeelIEAFSKRRAQIE 231
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1883232606  243 EAVGE------DASLKSRDVAALDTRKSK-QHVDPEVRMAEWMQTLKE 283
Cdd:pfam08751  232 AELAElgathgRAPPAARQIAALETRPAKhEPRSLAELRARWREEAAE 279
RecD COG0507
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ...
937-1468 1.80e-49

ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];


Pssm-ID: 440273 [Multi-domain]  Cd Length: 514  Bit Score: 184.79  E-value: 1.80e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  937 YEAEKSILRHILEGK------EAVTPLMERVPGELMEMLTSGQRAATRMILETSdRFTVVQGYAGVGKTTqfraVMSAVN 1010
Cdd:COG0507     87 LEAEQRLARRLRRLArpaldeADVEAALAALEPRAGITLSDEQREAVALALTTR-RVSVLTGGAGTGKTT----TLRALL 161
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1011 MLPESERPRVVGLGPTHRAVGEMR-SAGVDAQTLASFLH---DTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYAL 1086
Cdd:COG0507    162 AALEALGLRVALAAPTGKAAKRLSeSTGIEARTIHRLLGlrpDSGRFRHNRDNPLTPADLLVVDEASMVDTRLMAALLEA 241
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1087 IAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKEIVRQTPELREAVYS-LINR-DVERALSglesvkpsqvp 1164
Cdd:COG0507    242 LPRAGARLILVGDPDQLPSVGAGAVLRDLIESGTVPVVELTEVYRQADDSRIIELAhAIREgDAPEALN----------- 310
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1165 rqegAWAPEHSVTEFSHSQEAKlaeaqqkamlkgeafpdvpmtlyEAIVRDYTGRtPEAREQTLIVTHLNEDRRVLNSMI 1244
Cdd:COG0507    311 ----ARYADVVFVEAEDAEEAA-----------------------EAIVELYADR-PAGGEDIQVLAPTNAGVDALNQAI 362
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1245 HDAREKAGELGKEQvmvpvlntanIRDGELRrlstwethrdalalvdnvyhriagiskddglitlqdaegntrlisprea 1324
Cdd:COG0507    363 REALNPAGELEREL----------AEDGELE------------------------------------------------- 383
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1325 vaegvtlytpdtIRVgtGDRMRFTKSDRERGYVANSVWTVTAVSGDSVTLS---DGQQTRVIRPGQERaeqHIDLAYAIT 1401
Cdd:COG0507    384 ------------LYV--GDRVMFTRNDYDLGVFNGDIGTVLSIDEDEGRLTvrfDGREIVTYDPSELD---QLELAYAIT 446
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1883232606 1402 AHGAQGAseTF--AIALEGTEGNRklMAGFESAYVALSRMKQHVQVYTDNRQgWTDTINNAVQKGTAHD 1468
Cdd:COG0507    447 VHKSQGS--TFdrVILVLPSEHSP--LLSRELLYTALTRARELLTLVGDRDA-LARAVRRDTARATGLA 510
DEXSc_RecD-like cd17933
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ...
972-1130 1.69e-39

DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350691 [Multi-domain]  Cd Length: 155  Bit Score: 144.23  E-value: 1.69e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  972 GQRAATRMILetSDRFTVVQGYAGVGKTTQFRAVMSAVnmlpESERPRVVGLGPTHRAVGEMR-SAGVDAQTLASFLHDT 1050
Cdd:cd17933      1 EQKAAVRLVL--RNRVSVLTGGAGTGKTTTLKALLAAL----EAEGKRVVLAAPTGKAAKRLSeSTGIEASTIHRLLGIN 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1051 QLQQRS--GETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGgRAVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKE 1128
Cdd:cd17933     75 PGGGGFyyNEENPLDADLLIVDEASMVDTRLMAALLSAIPAGA-RLILVGDPDQLPSVGAGNVLRDLIASKGVPTVELTE 153

                   ..
gi 1883232606 1129 IV 1130
Cdd:cd17933    154 VF 155
 
Name Accession Description Interval E-value
PRK13709 PRK13709
conjugal transfer nickase/helicase TraI; Provisional
2-1751 0e+00

conjugal transfer nickase/helicase TraI; Provisional


Pssm-ID: 237478 [Multi-domain]  Cd Length: 1747  Bit Score: 3085.93  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606    2 MSIAQVRSAGSAGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNRHRPGYD 81
Cdd:PRK13709     1 MSIAQVKSAGSAGNYYTDKDNYYVLGSMGERWAGEGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYD 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   82 LTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAV 161
Cdd:PRK13709    81 LTFSAPKSVSMMAMLGGDKRLIEAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHAV 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  162 VANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVPVEAFSGRSQAI 241
Cdd:PRK13709   161 VANVTQHNGKWKTLSSDKVGKTGFIENVYANQIAFGKIYREALKEDVEALGYETEVVGKHGMWEMKGVPVEAFSSRSQEI 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  242 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAETRTQAPGAVSQEGPDVQQAVT 321
Cdd:PRK13709   241 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYREAADQRAEIRTQAPGPASQDGPDIQQAVT 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  322 QAIAGLSERKVQFTYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 401
Cdd:PRK13709   321 QAIAGLSDRKVQFTYTDLLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  402 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMVREQGREVQIIAADRRSQMNLKQDER 481
Cdd:PRK13709   401 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQILAADRRSQMNLKQDER 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  482 LSGELITGRRQLLEGMAFTPGSTVIVDQGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQ 561
Cdd:PRK13709   481 LSGELITGRRQLQEGMAFTPGSTLIVDQAEKLSLKETLTLLDGAARHNVQVLILDSGQRTGTGSALMVLKDAGVNTYRWQ 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  562 GGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVLGHQEVTMTALSPVWLDS 641
Cdd:PRK13709   561 GGEQRPATVISEPDKNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTGLIRSALKTQGVLGRPEVTITALSPVWLDS 640
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  642 RSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVT 721
Cdd:PRK13709   641 KSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVKISSLDSSWSLFRPEKMPVADGERLRVL 720
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  722 GKISGLRVSGGDRLQVASVSEDAMTVVVPGRAEPASLPVSDSPFTALKLENGWVETPGHSVSDSAKVFASVTQMAMDNAT 801
Cdd:PRK13709   721 GKIPGLRLKGGDRLQVTSVSEDGLTVVVPGRAEPATLPVDDSPFTALKLEHGWVETPGHSVSDSATVFASVTQRAMDNAT 800
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  802 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETSLETAISHQKSVLHTPAQQAIHLALPVVESKNLA 881
Cdd:PRK13709   801 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETDLETAISLQKAGLHTPAQQAIHLALPVLESKNLA 880
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  882 FSQVDLLTEAKSFAAEGTSFTELGGEIDAQIKRGDLLHVDVAKGYGTDLLVSRASYEAEKSILRHILEGKEAVTPLMERV 961
Cdd:PRK13709   881 FSMVDLLTEAKSFAAEGTSFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERV 960
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  962 PGELMEMLTSGQRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1041
Cdd:PRK13709   961 PGELMEGLTSGQRAATRMILESTDRFTVVQGYAGVGKTTQFRAVMSAVNTLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1040
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1042 TLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAA 1121
Cdd:PRK13709  1041 TLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVSSGDTDQLQAIAPGQPFRLMQTRSAA 1120
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1122 DVAIMKEIVRQTPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLkgeAF 1201
Cdd:PRK13709  1121 DVAIMKEIVRQTPELREAVYSLINRDVERALSGIESVKPSQVPRQEGAWAPESSVTEFSHPQEAKLAEAQQKAML---AF 1197
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1202 PDVPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWE 1281
Cdd:PRK13709  1198 PDVPMTLYEAIVRDYTGRTPEAREQTLIITHLNEDRRVLNSMIHDAREKAGELGKEQVTVPVLDTANIRDGELRRLSTWE 1277
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1282 THRDALALVDNVYHRIAGISKDDGLITLQDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1361
Cdd:PRK13709  1278 AHRGALALVDNVYHRIAGIDKDDGLITLRDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1357
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1362 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKLMAGFESAYVALSRMKQ 1441
Cdd:PRK13709  1358 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETYAIALEGTEGGRKQMAGFESAYVALSRMKQ 1437
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1442 HVQVYTDNRQGWTDTINNAVQKGTAHDVFEPKPDREVMNAERLFSTARELRDVAAGRAVLRQAGLAGGDSPARFIAPGRK 1521
Cdd:PRK13709  1438 HVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKPDREVMNAERLFSTARELRDTAAGRAVLRQAGLAGGDSPARFIAPGRK 1517
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1522 YPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1601
Cdd:PRK13709  1518 YPQPHVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSEDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1597
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1602 GVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1681
Cdd:PRK13709  1598 GVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1677
                         1690      1700      1710      1720      1730      1740      1750
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1682 GRTEQAVREIAGQERERAVTSEREAALPESVLREPQREREAVREVVRENLLQERLQQMERDMVRDLQKEK 1751
Cdd:PRK13709  1678 GKTEQAVRDIAGQERDRAAISEREAALPESVLREPQREREAVREVARENLLRERLQQMERDMVRDLQKEK 1747
PRK14712 PRK14712
conjugal transfer nickase/helicase TraI; Provisional
134-1756 0e+00

conjugal transfer nickase/helicase TraI; Provisional


Pssm-ID: 237796 [Multi-domain]  Cd Length: 1623  Bit Score: 2979.30  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  134 VLTGNLVMALFNHDTSRDQEPQLHTHAVVANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGY 213
Cdd:PRK14712     1 VLTGNLVMALFNHDTSRDQEPQLHTHAVVANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGY 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  214 ETEVVGKHGMWEMPGVPVEAFSGRSQAIREAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRD 293
Cdd:PRK14712    81 ETEVVGKHGMWEMPGVPVEAFSGRSQTIREAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRD 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  294 AADQRAETRTQAPGAVSQEGPDVQQAVTQAIAGLSERKVQFTYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPL 373
Cdd:PRK14712   161 AAEQRAYTRTQTPGPASQDGPDVQQAVTQAIAGLSERKVQFMYTDLLARTVGILPPENGVIERARAGIDEAISREQLIPL 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  374 DREKGLFTSGIHVLDELSVRALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELV 453
Cdd:PRK14712   241 DREKGLFTSGIHMLDELSVRALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELV 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  454 MMVREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLLEGMAFTPGSTVIVDQGEKLSLKETLTLLDGAARHNVQVL 533
Cdd:PRK14712   321 MMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLLEGMAFTPGSTVIVDQGEKLSLKETLTLLDGAARHNVQVL 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  534 ITDSGQRTGTGSALMAMKDAGVNTYRWQGGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQA 613
Cdd:PRK14712   401 ITDSGQRTGTGSALMAMKDAGVNTYRWQGGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQA 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  614 IRSELKTQGVLGHQEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVV 693
Cdd:PRK14712   481 IRSELKTQGVLGHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVTERVTAQSHSLTLRNAQGETQVV 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  694 RISSLDSSWSLFRPEKMPVADGERLRVTGKISGLRVSGGDRLQVASVSEDAMTVVVPGRAEPASLPVSDSPFTALKLENG 773
Cdd:PRK14712   561 RISSLDSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPATLPVSDSPFTALKLENG 640
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  774 WVETPGHSVSDSAKVFASVTQMAMDNATLNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETSLETAI 853
Cdd:PRK14712   641 WVETPGHSVSDSATVFASVTQMAMDNATLNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETLLETAI 720
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  854 SHQKSVLHTPAQQAIHLALPVVESKNLAFSQVDLLTEAKSFAAEGTSFTELGGEIDAQIKRGDLLHVDVAKGYGTDLLVS 933
Cdd:PRK14712   721 SLQKAGLHTPAQQAIHLALPVLESKNLAFSMVDLLTEAKSFAAEGTGFADLGGEINAQIKRGDLLYVDVAKGYGTGLLVS 800
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  934 RASYEAEKSILRHILEGKEAVTPLMERVPGELMEMLTSGQRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLP 1013
Cdd:PRK14712   801 RASYEAEKSILRHILEGKEAVTPLMERVPGELMEKLTSGQRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLP 880
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1014 ESERPRVVGLGPTHRAVGEMRSAGVDAQTLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGR 1093
Cdd:PRK14712   881 ESERPRVVGLGPTHRAVGEMRSAGVDAQTLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGR 960
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1094 AVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKEIVRQTPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPE 1173
Cdd:PRK14712   961 AVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIVRQTPELREAVYSLINRDVERALSGLERVKPSQVPRLEGAWAPE 1040
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1174 HSVTEFSHSQEAKLAEAQQKAMLKGEAFPDVPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGE 1253
Cdd:PRK14712  1041 HSVTEFSHSQEAKLAEAQQKAMLKGEAFPDVPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGE 1120
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1254 LGKEQVMVPVLNTANIRDGELRRLSTWETHRDALALVDNVYHRIAGISKDDGLITLQDAEGNTRLISPREAVAEGVTLYT 1333
Cdd:PRK14712  1121 LGQVQVMVPVLNTANIRDGELRRLSTWENNPDALALVDNVYHRIAGISKDDGLITLQDAEGNTRLISPREAVAEGVTLYT 1200
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1334 PDTIRVGTGDRMRFTKSDRERGYVANSVWTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETFA 1413
Cdd:PRK14712  1201 PDTIRVGTGDRIRFTKSDRERGYVANSVWTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETFA 1280
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1414 IALEGTEGNRKLMAGFESAYVALSRMKQHVQVYTDNRQGWTDTINNAVQKGTAHDVFEPKPDREVMNAERLFSTARELRD 1493
Cdd:PRK14712  1281 IALEGTEGNRKLMAGFESAYVALSRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVFEPKPDREVMNAERLFSTARELRD 1360
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1494 VAAGRAVLRQAGLAGGDSPARFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVA 1573
Cdd:PRK14712  1361 VAAGRAVLRQAGLAGGDSPARFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVA 1440
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1574 LQGSRNGESLLADNMQDGVRIARDNPDSGVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQA 1653
Cdd:PRK14712  1441 LQGSRNGESLLADNMQDGVRIARDNPDSGVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQA 1520
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1654 EEAIRRETERRADEIVRKMAENKPDLPDGRTEQAVREIAGQERERAVTSEREAALPESVLREPQREREAVREVVRENLLQ 1733
Cdd:PRK14712  1521 EEAIRRETERRADEIVRKMAENKPDLPDGKTEQAVREIAGQERDRAAITEREAALPESVLREPQRVREAVREVARENLLQ 1600
                         1610      1620
                   ....*....|....*....|...
gi 1883232606 1734 ERLQQMERDMVRDLQKEKTLGGD 1756
Cdd:PRK14712  1601 ERLQQMERDMVRDLQKEKTPGGD 1623
TraI_TIGR TIGR02760
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ...
1-1756 0e+00

conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.


Pssm-ID: 274285 [Multi-domain]  Cd Length: 1960  Bit Score: 1982.45  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606    1 MMSIAQVRSAGSAGNYYTDKDNYYVLGSM---GERWAGRGAEQLGLQG-SVDKDVFTRLLEGRLPDGADLSRMQDGSNRH 76
Cdd:TIGR02760    1 MMSISPLRSAGDAAAYYLDEDNYYLKDSKslnNTRWLGKGAEQLGLLGkPVEKEQFEALLSGTLPDGTQLGRIDKGGIHH 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   77 RPGYDLTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQ 155
Cdd:TIGR02760   81 RPGFDLTFSAPKSVSILALVGGDKRLIEAHDKAVKIAVSEMEKdAAQARQTVDGKTEFINTRNLVFAMFRHKTSRENDPQ 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  156 LHTHAVVANVTQ-HNGEWKTLSSDKVGKTGFI----ENVYANQIAFGRLYREKLKEQVEALGYETEVVGKhGMWEMPGVP 230
Cdd:TIGR02760  161 LHTHAVVQNMTHdSDGKWRSLASDMKGQKGVIegfrERIYNHQIYYGLLYRSKLAKKVEELGYQTASVGK-GQFEIQGVP 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  231 ---VEAFSGRSQAIREAVGEDA--SLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAETRTQA 305
Cdd:TIGR02760  240 eqvLTAFSKRRQQIDELVDEKGwsSAKARDIAALDTRKDKTYIDDETLMEKWQQECKDMGFDPHALVASSYKPENIVARF 319
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  306 PGAVSQegpDVQQAVTQAIAGLSERKVQFTYTDVLARTVGILPPENGVIER--ARAGIDEAISREQLIPLDREKGLFTSG 383
Cdd:TIGR02760  320 YGPSQI---DAQHAVEVAIAHLSQYSTQFEYEKLIEEAAKYFTAGNKIIDEidIKKAIDELIANGQLIPLFTQKGLFTTQ 396
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  384 IHVLDELSVRALSRDIMKQNRVTVHPEKSV--PRTAGYSDAVSVLAQDRPSLAIVSGQGGAaGQRERVAELVMMVREQGR 461
Cdd:TIGR02760  397 TMLTNEKELIARTEGGKGALRVIVSKQKLSefALSPSNKDAVSTLFTSTKRFIIINGFGGT-GSTEIAQLLLHLASEQGY 475
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  462 EVQIIAADRRSQMNLKQD-ERLSGELITGRRQLLEGM-------------AFTPGSTVIVDQGEKLSLKETLTLLDGAAR 527
Cdd:TIGR02760  476 EIQIITAGSLSAQELRQKiPRLASTFITWVKNLFNDDqdhtvqglldkssPFSNKDIFVVDEANKLSNNELLKLIDKAEQ 555
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  528 HNVQ-VLITDSGQRTG--TGSALMAMKDAGVNTYRWQGGEQRPATI-ISEPDRNVRYARLAGDFAASVKAGEESVAQVSG 603
Cdd:TIGR02760  556 HNSKlILLNDSAQRQGmsAGSAIDLLKEGGVTTYAWVDTKQQKASVeISEAVDKLRVDYIASAWLDLTPDRQNSQVLATT 635
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  604 VREQAILTQAIRSELKTQGVLGHQEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTL 683
Cdd:TIGR02760  636 HREQQDLTQIIRNALKQEGQLSRQEVTVPTLKPVNLTGIQRRNAAHYKQGMVIRFWQKGKIPHDDYVVTNVNKHNNTLTL 715
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  684 RDAQGETQVVRISSL---DSSWSLFRPEKMPVADGERLRVTGKISGLRVSGGDRLQVASVSEDAMTVV-VPGRaepaSLP 759
Cdd:TIGR02760  716 KDAQGKTQKFKPSSLkdlERPFSVYRPEQLEVAAGERLQVTGNHFHSRVRNGELLTVSSINNEGITLItEDGQ----TLH 791
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  760 VSDSPFTALKLENGWVETPGHSVSDSAKVFASVTQMAMDNATLNGLARSGRDVRLYSSLDET--RTAEKLARHPSFTVVS 837
Cdd:TIGR02760  792 LPHGALEDAHLDYGYVLTPYHTQPDDAKVFLGVKQYALSKALLNSLNRSASRVDLFTDLDEKaqRYLEKTRGIPSAIVVV 871
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  838 EQIKARAGE-------TSLETAISHQKSVLHTPAQQ-----AIHLALPVVESKNLAFSQVDLLTEAKSFAAEGTSFTELG 905
Cdd:TIGR02760  872 DQKQHLPDAvttnntdKSLEMDISDTLHALEAKAKDgknsiALQYALEKVSEKEAAFKQKELVTEAYVFAFEETGFAIKA 951
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  906 GEIDAQIKRGDLLHVDVAKGYGT-DLLVSRASYEAEKSILRHILEGKEAVTPLMERVPG----ELMEMLTSGQRAATRMI 980
Cdd:TIGR02760  952 AEIAAALKNRPKLYRLLSAEYGDgTRWTTRAALRTETSILLHILPGKETVTPLATRAQVflnlELLERLTHGQKQAIHLI 1031
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  981 LETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVDAQTLASFLHDTQLQQRSGEtp 1060
Cdd:TIGR02760 1032 ISTKDRFVAVQGLAGVGKTTMLESRYKPVLQAFESEQLQVIGLAPTHEAVGELKSAGVQAQTLDSFLTDISLYRNSGG-- 1109
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1061 DFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKEIVRQ--TPELRE 1138
Cdd:TIGR02760 1110 DFRNTLFILDESSMVSNFQLTHATELVQKSGSRAVSLGDIAQLQSLAAGKPFELAITFDIIDTAIMKEIVRQnnSAELKA 1189
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1139 AVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHsQEAKLAEAQQKAMLKGEAFPDVPMTLYEAIVRDYTG 1218
Cdd:TIGR02760 1190 AHNSLDKRSNPKALELLKNQNPLQHELMQNAAMPEIASDEQGL-QKHDLAKLAVNTEKPKKAQPDATVTLYREIVKDYLS 1268
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1219 RTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWEThRDALALVDNVYHRIA 1298
Cdd:TIGR02760 1269 RTPEFRENTLIIAHTNNDRTGIYPFIREGLIKQKELSKQQVTVPRLRSVNISSPELKTMMPFEK-GAVLRLKKDAYLTIA 1347
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1299 GISKDDGLITLQDAE-GNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSVWTVTAV-SGDSVTLSD 1376
Cdd:TIGR02760 1348 DIDREHGKLTVADIKtGSERDILPRQLDHTFTSLYSDSELPLAKGDKIRLRATDKNRGIKANEVYTVTQVvNGLSVQLSK 1427
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1377 GQQTRVIRPGQERaEQHIDLAYAITAHGAQGASETFAIALegtEGNRKLMAGFESAYVALSRMKQHVQVYTDNRQGWT-- 1454
Cdd:TIGR02760 1428 VKNSLSLKPIQAK-DKHWDYAYTRTADSAQGATYTFVIAL---IKGRLALTNYRSAYIDLTRASHHVELYTDNKEGTVks 1503
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1455 ---------------------------------------------------DTINNAV---------------------- 1461
Cdd:TIGR02760 1504 wkqreanktsaveteedyrpkqstqfnnraqpheepkyqqkngplkiqsaaEIINEALpayteslaktllgepntqksrr 1583
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1462 -----------------------------QKGTAHDVFEPKPD---REVMN----------------------------- 1480
Cdd:TIGR02760 1584 drytfgakgglkvsltgkyrglwhdfstgEKGTLIQLIEAKKGlsfKEALNqaasllgipqhyqlsinikapqlsntepq 1663
                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1481 --------AERLFSTARELRDVAAGRAVLRQAGLAGGDSPARFIAP-----GRKYPQPYVALPAFDRNGKSAGIWLNPLT 1547
Cdd:TIGR02760 1664 klnqlekrAKSLFQGSQELKGTLAEKYLKQHRGLASIDNDDIRFHPtvyssDKKNKHPALIAAARNEKGEITGIQITYLD 1743
                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1548 TDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGE-SLLADNMQDGVRIARDNPDSGVVVRIAGegrpwnpgaitggrvwg 1626
Cdd:TIGR02760 1744 KDDANKDKDMDNNKRVKGSISGQFVVINKGMQGDrSYIAEGIETGLSIALANPKATVVIAVGG----------------- 1806
                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1627 dipDNSVQPGAGNGEPVTAEVLAQRQAEEAIrreTERRADEIVRKMAENK-----------PDLPDGRTEQAVREIAGQE 1695
Cdd:TIGR02760 1807 ---KNNLSPIIPKFIPKNVVIVLDNDGEEAK---SQRAIEKIINKFKQDNisarivfpddwNDIGEEELQKQLMRAISSI 1880
                         1930      1940      1950      1960      1970      1980
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1883232606 1696 RERAVTSEREAALPESVLREPQREREAVREVVRENLLQERLQQM-------ERDMVRDLQKEKTLGGD 1756
Cdd:TIGR02760 1881 EDKDIEIPKAIADFESVLKMPNSDIISIIDNARTEREKSDLEQIvanehksQQALERDLNKEFTPDKR 1948
relax_trwC TIGR02686
conjugative relaxase domain, TrwC/TraI family; This domain is in the N-terminal (relaxase) ...
13-288 9.18e-139

conjugative relaxase domain, TrwC/TraI family; This domain is in the N-terminal (relaxase) region of TrwC, a relaxase-helicase that acts in plasmid R388 conjugation. The relaxase domain has DNA cleavage and strand transfer activities. Plasmid transfer protein TraI is also a member of this domain family. Members of this family on bacterial chromosomes typically are found near other genes typical of conjugative plasmids and appear to mark integrated plasmids. [Mobile and extrachromosomal element functions, Plasmid functions]


Pssm-ID: 274258 [Multi-domain]  Cd Length: 283  Bit Score: 431.11  E-value: 9.18e-139
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   13 AGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNRHRPGYDLTFSAPKSVSM 92
Cdd:TIGR02686    1 AADYYTDGDNYYLKDSDAGRWLGKGAQELGLSGEVEKKQFEALLEGRLPDGTRLGRIEDRQSKHRPGFDLTFSAPKSVSI 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   93 MAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAVVANVTQH-NG 170
Cdd:TIGR02686   81 LALVGGDPRLIDAHDEAVKFTLEQLEKeAAAARVTQDGEIEFEKTGNLVIALFRHDTSRANDPQLHTHAVVANMTRRsDG 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  171 EWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVP---VEAFSGRSQAIREAVGE 247
Cdd:TIGR02686  161 KWRSLSSDKKGKHGFIEEIYKNQIYLGLLYRAKLANELKELGYQTRVYGKHGNFEIDGVPeevIEAFSKRRQQIEEWVAE 240
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1883232606  248 D--ASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDI 288
Cdd:TIGR02686  241 RgwSLAKSRDTAALDTRKKKTVHDREALREEWQQTAKELGFDP 283
MobF NF041492
MobF family relaxase;
1-281 6.19e-112

MobF family relaxase;


Pssm-ID: 469380 [Multi-domain]  Cd Length: 288  Bit Score: 357.00  E-value: 6.19e-112
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606    1 MMSIAQVRSAGSAGNYYTDKD--NYYVLG--SMGERWAGRGAEQLGL-QGSVDKDVFTRLLEGRLPDGADLSRMQDGSNR 75
Cdd:NF041492     1 MLSIARIGSAGGAARYYTEKDldNYYSEDggTPAGRWFGKGAEALGLsGGAVDGERFKALLDGRLPDGERLRRRRKGAGR 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   76 HRPGYDLTFSAPKSVSMMAMLGGDKRLIDAHNQAVDFAVR-QVEALASTRVMTDGQSETVL--TGNLVMALFNHDTSRDQ 152
Cdd:NF041492    81 HRPGYDLTFSAPKSVSLLALVGGDKRLIEAHDEAVKEALEyLEERLAQTRVTVDGKGRTSLekTGNLVAALFRHDTSRAG 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  153 EPQLHTHAVVANVTQH-NGEWKTLSSdkvgktgfiENVYANQIAFGRLYREKLKEQVEALGYETEVVgKHGMWEMPGVP- 230
Cdd:NF041492   161 DPQLHTHAVVMNMTQRpDGKWRSLDN---------EELYKNQKALGAIYQAELAEELQALGYEIRET-KNGQFEIAGVPr 230
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1883232606  231 --VEAFSGRSQAIREAVGED----ASLKSRDVAALDTRKSKQ-HVDPEVRMAEWMQTL 281
Cdd:NF041492   231 eqIEAFSKRSQQIEEWLGENpatlASAALRQIAALDTRKAKEaDVDPEELEAEWREEA 288
TrwC pfam08751
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative ...
10-283 6.52e-97

TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative cell to cell DNA transfer. TrwC binds to the origin of transfer (oriT) and melts the double helix.


Pssm-ID: 430190 [Multi-domain]  Cd Length: 279  Bit Score: 313.78  E-value: 6.52e-97
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   10 AGSAGNYYTDKDNYYVL-GSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGRLPD-GADLSRMQDGSNRHRPGYDLTFSAP 87
Cdd:pfam08751    1 AGDAYAYYTRQDDYYTEgGEPPGRWLGKGAAALGLSGEVTEEQFEALLEGRHPDtGERLGRRRPRGRKHRAGFDLTFSAP 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606   88 KSVSMMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAVVANVT 166
Cdd:pfam08751   81 KSVSLLAAVGGDERIEAAHRAAVAEALAWLEKhAAQTRVGKDGGVEQVDTGGLVAAAFRHDTSRAGDPQLHTHVVVANVT 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  167 Q-HNGEWKTLSSDKvgktgfienVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVP---VEAFSGRSQAIR 242
Cdd:pfam08751  161 QrEDGKWRALDSRG---------LYKAQVAAGAVYRAELADELRRLGYEIEERGKRGVFEIAGVPeelIEAFSKRRAQIE 231
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1883232606  243 EAVGE------DASLKSRDVAALDTRKSK-QHVDPEVRMAEWMQTLKE 283
Cdd:pfam08751  232 AELAElgathgRAPPAARQIAALETRPAKhEPRSLAELRARWREEAAE 279
TraI pfam07057
DNA helicase TraI; This family represents a conserved region approximately 130 residues long ...
1434-1557 5.91e-83

DNA helicase TraI; This family represents a conserved region approximately 130 residues long within the bacterial DNA helicase TraI (EC:3.6.1.-). TraI is a bifunctional protein that catalyzes the unwinding of duplex DNA as well as acts as a sequence-specific DNA trans-esterase, providing the site- and strand-specific nick required to initiate DNA transfer.


Pssm-ID: 429268 [Multi-domain]  Cd Length: 124  Bit Score: 267.25  E-value: 5.91e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1434 VALSRMKQHVQVYTDNRQGWTDTINNAVQKGTAHDVFEPKPDREVMNAERLFSTARELRDVAAGRAVLRQAGLAGGDSPA 1513
Cdd:pfam07057    1 VALSRMKQHVQVYTDNRQGWIKAINNAPQKGTAHDVLEPKNDREVMNADRLFSTARELRDVAAGRAVLRQAGLAQGDSPA 80
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1883232606 1514 RFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGF 1557
Cdd:pfam07057   81 RFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGRGLRGF 124
RecD COG0507
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ...
937-1468 1.80e-49

ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];


Pssm-ID: 440273 [Multi-domain]  Cd Length: 514  Bit Score: 184.79  E-value: 1.80e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  937 YEAEKSILRHILEGK------EAVTPLMERVPGELMEMLTSGQRAATRMILETSdRFTVVQGYAGVGKTTqfraVMSAVN 1010
Cdd:COG0507     87 LEAEQRLARRLRRLArpaldeADVEAALAALEPRAGITLSDEQREAVALALTTR-RVSVLTGGAGTGKTT----TLRALL 161
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1011 MLPESERPRVVGLGPTHRAVGEMR-SAGVDAQTLASFLH---DTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYAL 1086
Cdd:COG0507    162 AALEALGLRVALAAPTGKAAKRLSeSTGIEARTIHRLLGlrpDSGRFRHNRDNPLTPADLLVVDEASMVDTRLMAALLEA 241
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1087 IAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKEIVRQTPELREAVYS-LINR-DVERALSglesvkpsqvp 1164
Cdd:COG0507    242 LPRAGARLILVGDPDQLPSVGAGAVLRDLIESGTVPVVELTEVYRQADDSRIIELAhAIREgDAPEALN----------- 310
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1165 rqegAWAPEHSVTEFSHSQEAKlaeaqqkamlkgeafpdvpmtlyEAIVRDYTGRtPEAREQTLIVTHLNEDRRVLNSMI 1244
Cdd:COG0507    311 ----ARYADVVFVEAEDAEEAA-----------------------EAIVELYADR-PAGGEDIQVLAPTNAGVDALNQAI 362
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1245 HDAREKAGELGKEQvmvpvlntanIRDGELRrlstwethrdalalvdnvyhriagiskddglitlqdaegntrlisprea 1324
Cdd:COG0507    363 REALNPAGELEREL----------AEDGELE------------------------------------------------- 383
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1325 vaegvtlytpdtIRVgtGDRMRFTKSDRERGYVANSVWTVTAVSGDSVTLS---DGQQTRVIRPGQERaeqHIDLAYAIT 1401
Cdd:COG0507    384 ------------LYV--GDRVMFTRNDYDLGVFNGDIGTVLSIDEDEGRLTvrfDGREIVTYDPSELD---QLELAYAIT 446
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1883232606 1402 AHGAQGAseTF--AIALEGTEGNRklMAGFESAYVALSRMKQHVQVYTDNRQgWTDTINNAVQKGTAHD 1468
Cdd:COG0507    447 VHKSQGS--TFdrVILVLPSEHSP--LLSRELLYTALTRARELLTLVGDRDA-LARAVRRDTARATGLA 510
DEXSc_RecD-like cd17933
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ...
972-1130 1.69e-39

DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350691 [Multi-domain]  Cd Length: 155  Bit Score: 144.23  E-value: 1.69e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  972 GQRAATRMILetSDRFTVVQGYAGVGKTTQFRAVMSAVnmlpESERPRVVGLGPTHRAVGEMR-SAGVDAQTLASFLHDT 1050
Cdd:cd17933      1 EQKAAVRLVL--RNRVSVLTGGAGTGKTTTLKALLAAL----EAEGKRVVLAAPTGKAAKRLSeSTGIEASTIHRLLGIN 74
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1051 QLQQRS--GETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGgRAVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKE 1128
Cdd:cd17933     75 PGGGGFyyNEENPLDADLLIVDEASMVDTRLMAALLSAIPAGA-RLILVGDPDQLPSVGAGNVLRDLIASKGVPTVELTE 153

                   ..
gi 1883232606 1129 IV 1130
Cdd:cd17933    154 VF 155
AAA_30 pfam13604
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
968-1156 1.79e-35

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.


Pssm-ID: 433343 [Multi-domain]  Cd Length: 191  Bit Score: 134.23  E-value: 1.79e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  968 MLTSGQRAATRMILETSDRFTVVQGYAGVGKTTqfraVMSAVNMLPESERPRVVGLGPTHRAVGEMR-SAGVDAQTLASF 1046
Cdd:pfam13604    1 TLNAEQAAAVRALLTSGDRVAVLVGPAGTGKTT----ALKALREAWEAAGYRVIGLAPTGRAAKVLGeELGIPADTIAKL 76
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1047 LHDTQLQQRSGetpdfSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFR-LQQTRsaADVAI 1125
Cdd:pfam13604   77 LHRLGGRAGLD-----PGTLLIVDEAGMVGTRQMARLLKLAEDAGARVILVGDPRQLPSVEAGGAFRdLLAAG--IGTAE 149
                          170       180       190
                   ....*....|....*....|....*....|..
gi 1883232606 1126 MKEIVRQT-PELREAVYSLINRDVERALSGLE 1156
Cdd:pfam13604  150 LTEIVRQRdPWQRAASLALRDGDPAEALDALA 181
TraI_2B pfam18340
DNA relaxase TraI 2B/2B-like domain; This is the 2B and 2B-like sub-domain found in TraI (EC:5. ...
633-712 1.91e-35

DNA relaxase TraI 2B/2B-like domain; This is the 2B and 2B-like sub-domain found in TraI (EC:5.99.1.2) a relaxase of F-family plasmids. It contains four domains; a trans-esterase domain that executes the nicking and covalent attachment of the T-strand to the relaxase, a vestigial helicase domain (carrying the 2B/2B-like sub-domain) that operates as an ssDNA-binding domain, an active 5' to 3' helicase domain, and a C-terminal domain that functions as a recruitment platform for relaxosome components. The 2B sub-domains in TraI are formed by residues 625-773 in the vestigial helicase domain and residues 1255-1397 in the active helicase domain. The 2B/2B-like sub-domain interacts with ssDNA where it contributes to the surface area where ssDNA bind. In other words the ssDNA-binding site is located in a groove between the 2B and 2B-like parts of the sub-domain. The sub-domain parts appear to act as clamps holding the ssDNA in place, resulting in the ssDNA being completely surrounded by protein. In previous studies, the 2B/2B-like sub-domain of the TraI vestigial helicase domain has been identified as translocation signal A (TSA) since it contains sequences essential for the recruitment of TraI to the T4S system. Thus, the 2B/2B-like sub-domain plays two major roles in relaxase function: (1) interacting with the DNA and possibly promoting high processivity and (2) mediating recruitment of the relaxosome to the T4S system.


Pssm-ID: 465718 [Multi-domain]  Cd Length: 79  Bit Score: 129.70  E-value: 1.91e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  633 ALSPVWLDSRSRYLRDMYRPGMVMEQWNPeTRSHDRYVIDRVTAQSHSLTLRDAQGETQVVRISSLDSSWSLFRPEKMPV 712
Cdd:pfam18340    1 TLTPVWLDSKNRRSRDSYREGMVLERWNG-ARKKQRFTIDRVTEKTNSLTLVDAKGETSTLKISEIDSHWRLFRSDKLEV 79
TraA_Ti TIGR02768
Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a ...
969-1450 2.48e-23

Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a single strand exonuclease (N-terminus, MobA/MobL, pfam03389) as well as a helicase domain (central region, homologous to the corresponding region of the F-type relaxase TraI, TIGR02760). This protein likely fills the same role as TraI(F), nicking (at the oriT site) and unwinding the coiled plasmid prior to conjugative transfer.


Pssm-ID: 274289 [Multi-domain]  Cd Length: 744  Bit Score: 107.58  E-value: 2.48e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  969 LTSGQRAATRMILEtSDRFTVVQGYAGVGKTTqfraVMSAVNMLPESERPRVVGLGPTHRAVGEMR-SAGVDAQTLASFl 1047
Cdd:TIGR02768  353 LSEEQYEAVRHVTG-SGDIAVVVGRAGTGKST----MLKAAREAWEAAGYRVIGAALSGKAAEGLQaESGIESRTLASL- 426
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1048 hdtQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRlqqtrsaadvAIMK 1127
Cdd:TIGR02768  427 ---EYAWANGRDLLSDKDVLVIDEAGMVGSRQMARVLKEAEEAGAKVVLVGDPEQLQPIEAGAAFR----------AIAE 493
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1128 EIvrqtpelreavyslinrdveralsglESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLKGEAFPDVPMt 1207
Cdd:TIGR02768  494 RI--------------------------GYAELETIRRQREAWARQASLELARGDVEKALAAYRDHGHITIHDTREEAI- 546
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1208 lyEAIVRDYTGRTPEAREQ--TLIVTHLNEDRRVLNSMIHDAREKAGELGKEqvmvpvlntanirdgelrrlstwethrd 1285
Cdd:TIGR02768  547 --EQVVADWKQDLREANPAgsQIMLAHTRKDVRALNEAAREALIERGELGES---------------------------- 596
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1286 alalvdnvyhriagiskddglITLQDAEGNTRLispreavaegvtlytpdtirvGTGDRMRFTKSDRERGYVANSVWTVT 1365
Cdd:TIGR02768  597 ---------------------ILFQTARGERKF---------------------AAGDRIVFLENNRDLGVKNGMLGTVE 634
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1366 AVSGD--SVTLSDGQQTRVirpgQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKLmagfesAYVALSRMKQHV 1443
Cdd:TIGR02768  635 EIEDGrlVVQLDSGELVII----PQAEYDALDHGYATTIHKSQGVTVDRAFVLASKSMDRHL------AYVAMTRHRESV 704

                   ....*..
gi 1883232606 1444 QVYTDNR 1450
Cdd:TIGR02768  705 QLYAGKE 711
ssDNA_TraI_N pfam18272
single-stranded DNA binding TraI N-terminal subdomain; This is a subdomain found in TraI ...
575-627 2.31e-18

single-stranded DNA binding TraI N-terminal subdomain; This is a subdomain found in TraI present in E. coli. Tra1 is a conjugative relaxase that forms part of the Type IV secretion system. This subdomain, referred to as 2A, is located in N-terminal region of the translocation signal (TSA) domain. TSA is known to reside in a larger ssDNA-binding domain.


Pssm-ID: 408086 [Multi-domain]  Cd Length: 53  Bit Score: 80.23  E-value: 2.31e-18
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1883232606  575 DRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVLGHQ 627
Cdd:pfam18272    1 DKAQRYGRLAKEFVQAVREGEESVAQVSGPREQAVLAGMIRDELKEEGVLGRE 53
PRK13826 PRK13826
Dtr system oriT relaxase; Provisional
967-1450 8.20e-12

Dtr system oriT relaxase; Provisional


Pssm-ID: 237524 [Multi-domain]  Cd Length: 1102  Bit Score: 70.58  E-value: 8.20e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  967 EMLTSGQRAATRMILETSdRFTVVQGYAGVGKTTQFRAVMSAVnmlpESERPRVVGLGPTHRAV-GEMRSAGVDAQTLAS 1045
Cdd:PRK13826   380 ARLSDEQKTAIEHVAGPA-RIAAVVGRAGAGKTTMMKAAREAW----EAAGYRVVGGALAGKAAeGLEKEAGIQSRTLSS 454
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1046 FlhdtQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAadVAI 1125
Cdd:PRK13826   455 W----ELRWNQGRDQLDNKTVFVLDEAGMVASRQMALFVEAVTRAGAKLVLVGDPEQLQPIEAGAAFRAIADRIG--YAE 528
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1126 MKEIVRQTPE-LREAVYSLINRDVERALSglesvkpsqvprqegawapehsvtefSHSQEAKLAEAQqkamLKGEAFPdv 1204
Cdd:PRK13826   529 LETIYRQREQwMRDASLDLARGNVGKALD--------------------------AYRANGRVIGSR----LKAEAVE-- 576
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1205 pmTLYEAIVRDYtgrtpEAREQTLIVTHLNEDRRVLNSMihdAREKagelgkeqvmvpvlntanirdgelrrlstwethr 1284
Cdd:PRK13826   577 --SLIADWNRDY-----DPTKTTLILAHLRRDVRMLNEM---ARAK---------------------------------- 612
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1285 dalaLVDnvyhriagiskddglitlqdaegntrlispREAVAEGVTLYTPDTIR-VGTGDRMRFTKSDRERGyVANSVW- 1362
Cdd:PRK13826   613 ----LVE------------------------------RGIVGEGHAFRTADGERrFAAGDQIVFLKNEGSLG-VKNGMIg 657
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1363 -TVTAVSGDSV-TLSDGQQTRVIRPGQeRAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKLmagfesAYVALSRMK 1440
Cdd:PRK13826   658 kVVEAAPNRIVaEIGEGEHRRQVTVEQ-RFYNNLDHGYATTIHKSQGATVDRVKVLASLSLDRHL------TYVAMTRHR 730
                          490
                   ....*....|
gi 1883232606 1441 QHVQVYTDNR 1450
Cdd:PRK13826   731 EDLQLYYGRR 740
AAA_19 pfam13245
AAA domain;
973-1103 1.15e-09

AAA domain;


Pssm-ID: 433059 [Multi-domain]  Cd Length: 136  Bit Score: 58.38  E-value: 1.15e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  973 QRAATRMILEtsDRFTVVQGYAGVGKTTQFRA-VMSAVNMLPESERprVVGLGPTHRAVGEMRSA-GVDAQTLASFLH-- 1048
Cdd:pfam13245    1 QREAVRTALP--SKVVLLTGGPGTGKTTTIRHiVALLVALGGVSFP--ILLAAPTGRAAKRLSERtGLPASTIHRLLGfd 76
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1883232606 1049 -DTQLQQRSGETPDFSNTLFLLDESSMVgntDMARAYALIAA--GGGRAVASGDTDQL 1103
Cdd:pfam13245   77 dLEAGGFLRDEEEPLDGDLLIVDEFSMV---DLPLAYRLLKAlpDGAQLLLVGDPDQL 131
SF1_C_RecD cd18809
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ...
1396-1447 7.58e-08

C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.


Pssm-ID: 350196 [Multi-domain]  Cd Length: 80  Bit Score: 51.41  E-value: 7.58e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1883232606 1396 LAYAITAHGAQGASETFAIALEGTEGNrklMAGFESAYVALSRMKQHVQVYT 1447
Cdd:cd18809     32 QAYAMTIHKSQGSEFDRVIVVLPTSHP---MLSRGLLYTALTRARKLLTLVG 80
PRK13889 PRK13889
conjugal transfer relaxase TraA; Provisional
968-1719 2.68e-06

conjugal transfer relaxase TraA; Provisional


Pssm-ID: 237546 [Multi-domain]  Cd Length: 988  Bit Score: 52.38  E-value: 2.68e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606  968 MLTSGQRAATRMILETSDrFTVVQGYAGVGKTTQFRAVMSAVnmlpESERPRVVGLGPTHRAVGEMRS-AGVDAQTLASF 1046
Cdd:PRK13889   346 VLSGEQADALAHVTDGRD-LGVVVGYAGTGKSAMLGVAREAW----EAAGYEVRGAALSGIAAENLEGgSGIASRTIASL 420
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1047 LHDTQlQQRSGETpdfSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAAdvAIM 1126
Cdd:PRK13889   421 EHGWG-QGRDLLT---SRDVLVIDEAGMVGTRQLERVLSHAADAGAKVVLVGDPQQLQAIEAGAAFRSIHERHGG--AEI 494
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1127 KEIVRQTPE-LREAVYSLINRDVERALsglesvkpsqvprqegawapeHSVTEFSHSQEAKLAEAQQKAmlkgeafpdvp 1205
Cdd:PRK13889   495 GEVRRQREDwQRDATRDLATGRTGEAL---------------------DAYEAHGMVHAAATREQARAD----------- 542
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1206 mtLYEAIVRDytgRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGkEQVMVPVlntanirdgelrrlstwethrd 1285
Cdd:PRK13889   543 --LIDRWDRD---RQAAPDRSRIILTHTNDEVRALNEAARERMRAAGDLG-DDVRVTV---------------------- 594
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1286 alalvdnvyhriagiskddglitlqdaEGNTRlispreavaegvtlytpdtiRVGTGDRMRFTKSDRERGYVANSVWTVT 1365
Cdd:PRK13889   595 ---------------------------ERGER--------------------SFASGDRVMFLQNERGLGVKNGTLGTIE 627
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1366 AVSGDSVT--LSDGQQTRVirpgQERAEQHIDLAYAITAHGAQGAS--ETFAIALEGTEGNrklmagfeSAYVALSRMKQ 1441
Cdd:PRK13889   628 QVSAQSMSvrLDDGRSVAF----DLKDYDRIDHGYAATIHKAQGMTvdRTHVLATPGMDAH--------SSYVALSRHRD 695
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1442 HVQVYT-----DNRQGWTDTINNAVQKGTAHDVFEPKPDREVmnAERLFSTARELRDVAAGRAV-LRQAGLAGGDSPARF 1515
Cdd:PRK13889   696 GVDLHYgrddfADRDRLVRTLSRDRAKDMASDYERADPAQSY--AERRGITFRERVAEIVRKIVpEKLRGMFDGLRLPDP 773
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1516 IAPGRkyPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIA 1595
Cdd:PRK13889   774 VPGPE--AGRRPERESAAATTDAPARTVAADPEAALRQARTRALVRHARAVDAIFRMQEQGGPVLPHQVKELQEARKAFE 851
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1596 RDNPDSGVVVRIAGEGRPWNPGAITGGRVwgdipdnsvqpgagngepvtAEVLAQRQAEEAIRRETERRADEIVRKMAen 1675
Cdd:PRK13889   852 EVRPYGSHDAEAAYKKNPELAAEAASGRP--------------------ARAIRALQLETELRTDPARRADRFVERWQ-- 909
                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1676 KPDLPDGRTEQAvREIAGQERERAVTS------EREAALpESVLREPQRE 1719
Cdd:PRK13889   910 KLDRASQRQYQA-GDMSGYKATRAAMGdmakslERDPQL-ESLLAGRKRE 957
DUF4659 pfam15558
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...
1645-1741 7.82e-04

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.


Pssm-ID: 464768 [Multi-domain]  Cd Length: 374  Bit Score: 43.87  E-value: 7.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1645 AEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLP--------DGRTEQAVREIAGQERERAVTSEREAALPESVLREP 1716
Cdd:pfam15558   20 EQRMRELQQQAALAWEELRRRDQKRQETLERERRLLlqqsqeqwQAEKEQRKARLGREERRRADRREKQVIEKESRWREQ 99
                           90       100
                   ....*....|....*....|....*
gi 1883232606 1717 QREREAVRevvRENLLQERLQQMER 1741
Cdd:pfam15558  100 AEDQENQR---QEKLERARQEAEQR 121
PRK02292 PRK02292
V-type ATP synthase subunit E; Provisional
1641-1750 3.95e-03

V-type ATP synthase subunit E; Provisional


Pssm-ID: 235026 [Multi-domain]  Cd Length: 188  Bit Score: 40.37  E-value: 3.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883232606 1641 EPVTAEVLAQRQAE-EAIRRETERRADEIVRKMAENKPDLPDGRTEQAVREIAgQERERAVTSereAALpesvlrEPQRE 1719
Cdd:PRK02292     4 ETVVEDIRDEARARaSEIRAEADEEAEEIIAEAEADAEEILEDREAEAEREIE-QLREQELSS---AKL------EAKRE 73
                           90       100       110
                   ....*....|....*....|....*....|....
gi 1883232606 1720 R-EAVREVVRE--NLLQERLQQMERDMVRDLQKE 1750
Cdd:PRK02292    74 RlNARKEVLEDvrNQVEDEIASLDGDKREELTKS 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH