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Conserved domains on  [gi|1864817253|ref|WP_176990886|]
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MULTISPECIES: NAD kinase [Stenotrophomonas]

Protein Classification

NAD kinase( domain architecture ID 10012223)

ATP-dependent NAD kinase catalyzes the phosphorylation of NAD to NADP

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 11-255 6.09e-158

inorganic polyphosphate/ATP-NAD kinase; Reviewed


:

Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 438.10  E-value: 6.09e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  11 ASSTEAAQLALAQMRARYGDYTPEQAEVLCPLGGDGFLLQALHRYGALGKPVFGMKLGTVGFLMNQFRDDDLPARLAAAE 90
Cdd:PRK04761    1 ASPTPEAQAALEELVKRYGDVPIEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLMNEYSEDDLLERIAAAE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  91 PANLRPLEMLALTESGTTTGSLAYNDVSLLRQTRQAAHIGIDLNGQERVAELIGDGVLVATPAGSTAYNYSAHGPILPLG 170
Cdd:PRK04761   81 PTVLHPLRMTATDVSGEVHEALAINEVSLFRQTRQAAKLRISIDGKVRMEELVCDGVLVATPAGSTAYNLSAHGPILPLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 171 SHTIALTPLAPYRPRRWRGAILKADTEVRFRVLDPYKRPVSVTADSHETRDVVEVTIRESRERRVTMLFDPEHNLEDRIL 250
Cdd:PRK04761  161 SNLLALTPISPFRPRRWRGALLPNSATVRFDVLEPDKRPVSAVADNTEVRDVVEVTIREDKDITVTLLFDPGHSLEERIL 240


                  ....*
gi 1864817253 251 SEQFM 255
Cdd:PRK04761  241 AEQFG 245
 
Name Accession Description Interval E-value
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 11-255 6.09e-158

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 438.10  E-value: 6.09e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  11 ASSTEAAQLALAQMRARYGDYTPEQAEVLCPLGGDGFLLQALHRYGALGKPVFGMKLGTVGFLMNQFRDDDLPARLAAAE 90
Cdd:PRK04761    1 ASPTPEAQAALEELVKRYGDVPIEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLMNEYSEDDLLERIAAAE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  91 PANLRPLEMLALTESGTTTGSLAYNDVSLLRQTRQAAHIGIDLNGQERVAELIGDGVLVATPAGSTAYNYSAHGPILPLG 170
Cdd:PRK04761   81 PTVLHPLRMTATDVSGEVHEALAINEVSLFRQTRQAAKLRISIDGKVRMEELVCDGVLVATPAGSTAYNLSAHGPILPLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 171 SHTIALTPLAPYRPRRWRGAILKADTEVRFRVLDPYKRPVSVTADSHETRDVVEVTIRESRERRVTMLFDPEHNLEDRIL 250
Cdd:PRK04761  161 SNLLALTPISPFRPRRWRGALLPNSATVRFDVLEPDKRPVSAVADNTEVRDVVEVTIREDKDITVTLLFDPGHSLEERIL 240


                  ....*
gi 1864817253 251 SEQFM 255
Cdd:PRK04761  241 AEQFG 245
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
6-255 7.49e-71

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 218.47  E-value: 7.49e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253   6 RIAFLAS-STEAAQLALAQMRARYGDY-------------------TPEQAEVLCPLGGDGFLLQALHRYGALGKPVFGM 65
Cdd:COG0061     3 RIAIVAKpGKPEALEAAEELAELLEERgievvldedtavpgvpleeLGEEADLVIVLGGDGTLLRAARLLAPLGIPILGI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  66 KLGTVGFLMNQFRDD--DLPARLAAAEPANLRP--LEMLALTESGTTTGSLAYNDVSLLRQTR-QAAHIGIDLNGqERVA 140
Cdd:COG0061    83 NLGRLGFLTEIEPEEleEALERLLAGEYEVEERllLEATVDRDGEVVHEALALNEVVVLRGSIaRMIELEVYIDG-EFLE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 141 ELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPYRPrRWRGAILKADTEVRFRVLDPYkRPVSVTADSHETR 220
Cdd:COG0061   162 EFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTL-SSRPLVLPDDSEIEIEVLEDS-RPAVLVADGQEVR 239

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1864817253 221 DV---VEVTIRESrERRVTMLFDPEHNLEDRiLSEQFM 255
Cdd:COG0061   240 DLepgDRVEIRRS-PKPVRLLRLKDHSFFER-LREKLG 275
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 139-226 3.87e-06

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 44.98  E-value: 3.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 139 VAELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPYrPRRWRGAILKADTEVRFRVLDPyKRPVSVTADSHE 218
Cdd:pfam20143  26 LGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPH-SLSSRPIVVSSSSKLRIRVLSR-AEALLVDDGDPE 103

                          90
                  ....*....|..
gi 1864817253 219 T----RDVVEVT 226
Cdd:pfam20143 104 LdispGDRVRVR 115
 
Name Accession Description Interval E-value
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 11-255 6.09e-158

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 438.10  E-value: 6.09e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  11 ASSTEAAQLALAQMRARYGDYTPEQAEVLCPLGGDGFLLQALHRYGALGKPVFGMKLGTVGFLMNQFRDDDLPARLAAAE 90
Cdd:PRK04761    1 ASPTPEAQAALEELVKRYGDVPIEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLMNEYSEDDLLERIAAAE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  91 PANLRPLEMLALTESGTTTGSLAYNDVSLLRQTRQAAHIGIDLNGQERVAELIGDGVLVATPAGSTAYNYSAHGPILPLG 170
Cdd:PRK04761   81 PTVLHPLRMTATDVSGEVHEALAINEVSLFRQTRQAAKLRISIDGKVRMEELVCDGVLVATPAGSTAYNLSAHGPILPLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 171 SHTIALTPLAPYRPRRWRGAILKADTEVRFRVLDPYKRPVSVTADSHETRDVVEVTIRESRERRVTMLFDPEHNLEDRIL 250
Cdd:PRK04761  161 SNLLALTPISPFRPRRWRGALLPNSATVRFDVLEPDKRPVSAVADNTEVRDVVEVTIREDKDITVTLLFDPGHSLEERIL 240


                  ....*
gi 1864817253 251 SEQFM 255
Cdd:PRK04761  241 AEQFG 245
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
6-255 7.49e-71

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 218.47  E-value: 7.49e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253   6 RIAFLAS-STEAAQLALAQMRARYGDY-------------------TPEQAEVLCPLGGDGFLLQALHRYGALGKPVFGM 65
Cdd:COG0061     3 RIAIVAKpGKPEALEAAEELAELLEERgievvldedtavpgvpleeLGEEADLVIVLGGDGTLLRAARLLAPLGIPILGI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  66 KLGTVGFLMNQFRDD--DLPARLAAAEPANLRP--LEMLALTESGTTTGSLAYNDVSLLRQTR-QAAHIGIDLNGqERVA 140
Cdd:COG0061    83 NLGRLGFLTEIEPEEleEALERLLAGEYEVEERllLEATVDRDGEVVHEALALNEVVVLRGSIaRMIELEVYIDG-EFLE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 141 ELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPYRPrRWRGAILKADTEVRFRVLDPYkRPVSVTADSHETR 220
Cdd:COG0061   162 EFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTL-SSRPLVLPDDSEIEIEVLEDS-RPAVLVADGQEVR 239

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1864817253 221 DV---VEVTIRESrERRVTMLFDPEHNLEDRiLSEQFM 255
Cdd:COG0061   240 DLepgDRVEIRRS-PKPVRLLRLKDHSFFER-LREKLG 275
pnk PRK14077
NAD(+) kinase;
37-226 1.07e-19

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 85.99  E-value: 1.07e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  37 EVLCPLGGDGFLLQALHRYGALGKPVFGMKLGTVGFL----MNQ---FRDDDLPARLAAAEPANLrplEMLALTESGTTT 109
Cdd:PRK14077   66 DFLISLGGDGTLISLCRKAAEYDKFVLGIHAGHLGFLtditVDEaekFFQAFFQGEFEIEKPYML---SVFLEKKQGKIL 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 110 GSLAYNDVSLLRQTRQA-AHIGIDLNGQeRVAELIGDGVLVATPAGSTAYNYSAHGPIL-PLgSHTIALTPLAPYRPRRw 187
Cdd:PRK14077  143 EKLAFNDVVISKNNQASmAHIEAFLNEK-YFNEYFGDGVIVATPAGSTAYNMSANGPIIyPL-SQVFILTPVCSHSLTQ- 219

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1864817253 188 RGAILKADTEVRFRVldpyKRPVSVTADSHETRDVVEVT 226
Cdd:PRK14077  220 RPIVLPKGFEVEFKT----KSDCILCIDGQDRYKMNDFK 254
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 33-202 3.43e-19

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 84.59  E-value: 3.43e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  33 PEQAEVLCPLGGDGFLLQALHRYGALGKPVFGMKLGTVGFLMNqFRDDDLPARLAAAEPANLRPLE--MLALTESGTTTG 110
Cdd:PRK01911   62 DGSADMVISIGGDGTFLRTATYVGNSNIPILGINTGRLGFLAT-VSKEEIEETIDELLNGDYTIEErsLLQLESNPKLFG 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 111 SLAY--NDVSLLRqTRQAAHIGID--LNGqERVAELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPY---- 182
Cdd:PRK01911  141 ELNFalNEIAILK-RDTSSMITVHtyLNG-EYLNSYWADGLIVATPTGSTGYSLSCGGPIIVPDAKSFVITPIAPHnlnv 218

                         170       180
                  ....*....|....*....|
gi 1864817253 183 RPrrwrgAILKADTEVRFRV 202
Cdd:PRK01911  219 RP-----LVIPDDTEITLEV 233
ppnK PRK01185
NAD(+) kinase;
36-250 1.80e-15

NAD(+) kinase;


Pssm-ID: 179241 [Multi-domain]  Cd Length: 271  Bit Score: 74.08  E-value: 1.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  36 AEVLCPLGGDGFLLQALHRygALGkPVFGMKLGTVGFLmNQFRDDDLPARLAAAEPANLRPLEMLAL--------TESGT 107
Cdd:PRK01185   53 ADVIITIGGDGTILRTLQR--AKG-PILGINMGGLGFL-TEIEIDEVGSAIKKLIRGEYFIDERMKLkvyingerLEDCT 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 108 TTGSLAYNDVSLLRQTRqaahigIDLNGqERVAELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPYRpRRW 187
Cdd:PRK01185  129 NEAVIHTDRIAKIRQFK------IYYDG-HFLDTFKADGVIVATPTGSTSYSSSAGGPILLPNLEGMVISYIAPYS-SRP 200

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1864817253 188 RGAILKADTEVRFRVLDPyKRPVSVTADSHETR----DVVEVTIRESRERRVTMLFDPEHNLEDRIL 250
Cdd:PRK01185  201 KSVVVPSESTVEIKIAGD-QSSLLILDGQYEYKiskgDTVEISKSENYARFISFRESPYDRIREKLI 266
pnk PRK14075
NAD(+) kinase;
42-244 3.80e-15

NAD(+) kinase;


Pssm-ID: 184489 [Multi-domain]  Cd Length: 256  Bit Score: 72.84  E-value: 3.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  42 LGGDGFLLQALHRygaLGKPVFGMKLGTVGFLmNQFRDDDLPARLAAAEPANLRPLEMLALTESGTTTGSLAYNDVSLLR 121
Cdd:PRK14075   48 VGGDGTVLKAAKK---VGTPLVGFKAGRLGFL-SSYTLEEIDRFLEDLKNWNFREEKRWFLKIESELGNHLALNDVTLER 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 122 QTRQAAhIGIDLNGQERVAELI-GDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPYRPRRwRGAILKADTEVRF 200
Cdd:PRK14075  124 DPSQKM-VEIEVSFEDHSSMWFfADGVVISTPTGSTAYSLSLGGPIILPNCEVFEITPIAPQFLAT-RSIVIPSNEKVTV 201

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1864817253 201 RVLdpykRPVSVTADSHETRDVVEVTIRESReRRVTMLFDPEHN 244
Cdd:PRK14075  202 ESQ----RDINLIVDGVLVGKTNRITVKKSR-RYVRILRPKDYD 240
ppnK PRK02155
NAD kinase;
35-244 1.12e-14

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 71.90  E-value: 1.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  35 QAEVLCPLGGDGFLLQALHRYGALGKPVFGMKLGTVGFLMNQFRDD---DLPARLAAAEPANLRPLEMLALTESGTTT-G 110
Cdd:PRK02155   63 RADLAVVLGGDGTMLGIGRQLAPYGVPLIGINHGRLGFITDIPLDDmqeTLPPMLAGNYEEEERMLLEARVVRDGEPIfH 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 111 SLAYNDVSLLR-QTRQAAHIGIDLNGqERVAELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPY----RPr 185
Cdd:PRK02155  143 ALAFNDVVVNRsGFSGMVELRVSVDG-RFMYNQRSDGLIVATPTGSTAYALSAGGPILHPQLPGWVLVPIAPHtlsnRP- 220

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1864817253 186 rwrgAILKADTEVRFRVLdpYKRPVSVTADSHETRDVVE---VTIRESRErRVTMLFDPEHN 244
Cdd:PRK02155  221 ----IVLPDDSEVAIQIV--GGRDVSVNFDMQSLTSLELgdrIEVRRSPH-TVRFLHPVGYS 275
ppnK PRK01231
NAD(+) kinase;
43-244 1.66e-13

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 68.45  E-value: 1.66e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  43 GGDGFLL---QALHRYGAlgkPVFGMKLGTVGFLMNqFRDDDLPARLAAA-------EPANLrpLEMLALTESGTTTGSL 112
Cdd:PRK01231   70 GGDGSLLgaaRALARHNV---PVLGINRGRLGFLTD-IRPDELEFKLAEVldghyqeEERFL--LEAEVRRGGEVIGQGD 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 113 AYNDVSLLRQtrQAAH-IGIDL--NGQErVAELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPY----RPr 185
Cdd:PRK01231  144 ALNDVVLHPG--KSTRmIEFELyiDGQF-VCSQRSDGLIVSTPTGSTAYALSGGGPIMHPKLDAIVLVPMFPHtlssRP- 219

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1864817253 186 rwrgAILKADTEVRFRVLDPYKRPVSVTADSHETRDVV---EVTIRESRErRVTMLFDPEHN 244
Cdd:PRK01231  220 ----IVVDGNSEIKIVISKDNRTYPRVSCDGQNSVTLApgdTVTIRKKPQ-KLRLIHPLDYN 276
ppnK PRK03708
NAD(+) kinase;
42-230 9.91e-13

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 66.27  E-value: 9.91e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  42 LGGDGFLLQALHRYGAlGKPVFGMKLGTVGFLMNQFRDDDLPA--RLAAAEPANLRPLEMLALTESGTTTGSLayNDVSL 119
Cdd:PRK03708   64 IGGDGTILRIEHKTKK-DIPILGINMGTLGFLTEVEPEETFFAlsRLLEGDYFIDERIKLRVYINGENVPDAL--NEVVI 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 120 LrqTRQAA---HIGIDLNGqERVAELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPYrPRRWRGAILKADT 196
Cdd:PRK03708  141 L--TGIPGkiiHLKYYVDG-ELADEVRADGLIISTPTGSTAYAMSAGGPFVDPRLDAILIAPLCPF-KLSSRPMVVPSSS 216

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1864817253 197 EVRFRVLDPYKRPVSVTADSHETR--DVVEVTIRES 230
Cdd:PRK03708  217 RIDVKLLRTGREIILVIDGQYYEElpPDTEITIKKS 252
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 36-181 1.65e-12

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 65.65  E-value: 1.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  36 AEVLCPLGGDGFLLQALHRYGALGKPVFGMKLGTVGFLMN---QFRDDDLPARLAAAEPANLRPLEMLALTESGTTTGS- 111
Cdd:PRK04539   69 CDLVAVLGGDGTFLSVAREIAPRAVPIIGINQGHLGFLTQiprEYMTDKLLPVLEGKYLAEERILIEAALIREGKTAERa 148

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1864817253 112 LAYNDVSLlrqTRQAAHIGIDLN---GQERVAELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAP 181
Cdd:PRK04539  149 LALNDAVL---SRGGAGQMIEFEvfvNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICP 218
ppnK PRK02645
NAD(+) kinase;
9-181 2.95e-11

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 62.24  E-value: 2.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253   9 FLASSTEAAQLALAqmrarygdytpeqaevlcpLGGDGFLLQALHRYGALGKPVFGMKLG-TVGFL---MNQFRDDDLPA 84
Cdd:PRK02645   50 FLASASELIDLAIV-------------------LGGDGTVLAAARHLAPHDIPILSVNVGgHLGFLthpRDLLQDESVWD 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  85 RLAAAEPANLRPLEMLALTESGTTTGS-------LAYNDV---SLLRQTRQAAHIGIDLNGqERVAELIGDGVLVATPAG 154
Cdd:PRK02645  111 RLQEDRYAIERRMMLQARVFEGDRSNEepvsesyYALNDFylkPASEDRSPTCILELEIDG-EVVDQYQGDGLIVSTPTG 189

                         170       180
                  ....*....|....*....|....*..
gi 1864817253 155 STAYNYSAHGPILPLGSHTIALTPLAP 181
Cdd:PRK02645  190 STAYTMAAGGPILHPGIDAIIVTPICP 216
ppnK PRK04885
inorganic polyphosphate/ATP-NAD kinase; Provisional
 6-167 1.69e-10

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235317 [Multi-domain]  Cd Length: 265  Bit Score: 59.83  E-value: 1.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253   6 RIAFLASSTEAAQLALAQMRARYGD----YTPEQAEVLCPLGGDGFLLQALHRY-GALGKPVF-GMKLGTVGFLMNqFRD 79
Cdd:PRK04885    2 KVAIISNGDPKSKRVASKLKKYLKDfgfiLDEKNPDIVISVGGDGTLLSAFHRYeNQLDKVRFvGVHTGHLGFYTD-WRP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  80 ---DDLPARLAAAEPANLR-P-LEMLALTESGTTTGSLAYNDVSLLRQTRQ-AAHIGIdlNGQ--ERVAeliGDGVLVAT 151
Cdd:PRK04885   81 fevDKLVIALAKDPGQVVSyPlLEVKITYEDGEKEKYLALNEATIKRIEGTlVADVYI--NGVlfERFR---GDGLCVST 155

                         170
                  ....*....|....*.
gi 1864817253 152 PAGSTAYNYSAHGPIL 167
Cdd:PRK04885  156 PTGSTAYNKSLGGAVL 171
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
42-204 3.31e-10

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 59.74  E-value: 3.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  42 LGGDGFLLQALHRYGALGKPVFGMKLGTVGFLmNQFRDDDLPARLAAAEPANLR-----PLEMLALTESGTTTGSLAYND 116
Cdd:PRK14076  355 IGGDGTVLRASKLVNGEEIPIICINMGTVGFL-TEFSKEEIFKAIDSIISGEYEiekrtKLSGFILKDGHQNILPSALNE 433

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 117 VSLLrqTRQAA---HIGIDLNGqERVAELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPY----RPrrwrg 189
Cdd:PRK14076  434 VVIT--TKNPAkmlHFEVYVNG-ELVEEVRADGIIISTPTGSTAYSLSAGGPIVEPTVDGFIIVPICPFklssRP----- 505

                         170
                  ....*....|....*
gi 1864817253 190 AILKADTEVRFRVLD 204
Cdd:PRK14076  506 LVVSANSEIKIKLLK 520
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 33-167 6.99e-10

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 58.39  E-value: 6.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  33 PEQAEVLCPLGGDGFLLQALHRYGALGKPVFGMKLGTVGFLMnQFRDDDLPARLAAAEPANLRPLEMLAL----TESGTT 108
Cdd:PRK03372   70 ADGCELVLVLGGDGTILRAAELARAADVPVLGVNLGHVGFLA-EAEAEDLDEAVERVVDRDYRVEERMTLdvtvRVGGEI 148

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1864817253 109 TGS-LAYNDVSLLRQTRQA---AHIGIDlngqER-VAELIGDGVLVATPAGSTAYNYSAHGPIL 167
Cdd:PRK03372  149 VWRgWALNEASLEKADREGmleVVLEVD----GRpVSSFGCDGVLVSTPTGSTAYAFSAGGPVV 208
ppnK PRK00561
NAD(+) kinase;
36-207 9.45e-09

NAD(+) kinase;


Pssm-ID: 100598 [Multi-domain]  Cd Length: 259  Bit Score: 54.50  E-value: 9.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  36 AEVLCPLGGDGFLLQALHRYGALGKPVFGMKLGTVGFlMNQFRDDDLPARLAaaepANLRPLEM--LALTESGTTTGS-L 112
Cdd:PRK00561   34 ADYLFVLGGDGFFVSTAANYNCAGCKVVGINTGHLGF-YTSFNETDLDQNFA----NKLDQLKFtqIDLLEVQIDDQIhL 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 113 AYNDVSLLRQTRQAAHIGIDLNGQERVAeliGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAP-YRPRR---WR 188
Cdd:PRK00561  109 VLNELAVYTNTAYPINIFIDNEFWEKYR---GSGLLIGPRTGSTALAKSAKGAVIFPRIDVIQIIELNPlLHPNQttiQS 185

                         170
                  ....*....|....*....
gi 1864817253 189 GAILKADTEVRFRVLDPYK 207
Cdd:PRK00561  186 PIILPIDTKVEFEIKKAFD 204
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 145-233 4.33e-08

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 52.64  E-value: 4.33e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 145 DGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPY----RPrrwrgAILKADTEVRFRVlDPYKRPVSVTADSHETR 220
Cdd:PRK03378  177 DGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHtlsaRP-----LVIDSSSTIRLKF-SPNRSDLEISCDSQIAL 250

                          90
                  ....*....|....*.
gi 1864817253 221 DVV---EVTIRESRER 233
Cdd:PRK03378  251 PIQpgeEVLIRRSDYH 266
ppnK PRK02649
NAD(+) kinase;
42-182 4.36e-08

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 53.06  E-value: 4.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  42 LGGDGFLLQALHRYGALGKPVFGMKLGTVGFLMNQFRDDdLPARLAAA--------EPANLrplEMLALTESGTTTGSLA 113
Cdd:PRK02649   75 LGGDGTVLSAARQLAPCGIPLLTINTGHLGFLTEAYLNQ-LDEAIDQVlagqytieERTML---TVSVMRGDQLRWEALS 150

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 114 YNDVSLLRQTRQA-AHIGIDLnGQERVAELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPY 182
Cdd:PRK02649  151 LNEMVLHREPLTSmCHFEIAI-GRHAPVDIAADGVILSTPTGSTAYSLSAGGPVITPDVPVLQLTPICPH 219
ppnK PRK02231
NAD(+) kinase;
16-184 1.59e-07

NAD(+) kinase;


Pssm-ID: 167337 [Multi-domain]  Cd Length: 272  Bit Score: 50.96  E-value: 1.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  16 AAQLALAQMRARYGDYTPEQAEVLCPLGGDGFLLQALHRYGALGKPVFGMKLGTVGFLMnqfrdDDLPARLAAAEPANLR 95
Cdd:PRK02231   23 AEQLNLPENHLASLEEIGQRAQLAIVIGGDGNMLGRARVLAKYDIPLIGINRGNLGFLT-----DIDPKNAYEQLEACLE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  96 P----------LEMLALTESGTTTGSLAYNDVSLlrQTRQAAHIgID----LNGQERVAELiGDGVLVATPAGSTAYNYS 161
Cdd:PRK02231   98 RgeffveerflLEAKIERNGKIIATSNALNEVVI--HPAKIAHM-IDfhvyIDDKFAFSQR-SDGLIISTPTGSTAYSLS 173

                         170       180
                  ....*....|....*....|....*..
gi 1864817253 162 AHGPILPLGSHTIALTPLAPY----RP 184
Cdd:PRK02231  174 AGGPILTPNLNAIALVPMFPHtlssRP 200
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 139-226 3.87e-06

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 44.98  E-value: 3.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 139 VAELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAPYrPRRWRGAILKADTEVRFRVLDPyKRPVSVTADSHE 218
Cdd:pfam20143  26 LGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPH-SLSSRPIVVSSSSKLRIRVLSR-AEALLVDDGDPE 103

                          90
                  ....*....|..
gi 1864817253 219 T----RDVVEVT 226
Cdd:pfam20143 104 LdispGDRVRVR 115
ppnK PRK03501
NAD kinase;
33-204 1.10e-05

NAD kinase;


Pssm-ID: 179584  Cd Length: 264  Bit Score: 45.35  E-value: 1.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  33 PEQAEVLCPLGGDGFLLQALHRYG----ALGKPVfgMKLGTVGFLMNqFRDDDLPARLAAAEPANL--RPLEMLALTESG 106
Cdd:PRK03501   37 PKNANIIVSIGGDGTFLQAVRKTGfredCLYAGI--STKDQLGFYCD-FHIDDLDKMIQAITKEEIevRKYPTIEVTVDG 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 107 TTTgSLAYNDVSLLRQTRQAAHIGIDLNGQE----RvaeliGDGVLVATPAGSTAYNYSAHGPIL-PLgSHTIALTPLAP 181
Cdd:PRK03501  114 STS-FYCLNEFSIRSSIIKTFVIDVYIDDLHfetfR-----GDGMVVSTPTGSTAYNKSVRGAVVdPL-IPCFQVSELAS 186

                         170       180
                  ....*....|....*....|....*..
gi 1864817253 182 YRPRRWR--GA--ILKADTEVRFRVLD 204
Cdd:PRK03501  187 LNNNTYRtlGSpfILSHERKLTLKIVQ 213
PLN02727 PLN02727
NAD kinase
 38-184 8.85e-05

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 43.34  E-value: 8.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  38 VLCpLGGDGFLLQALHRYGALGKPVFGMKLGTVGFLMNQ----FRDD----------------DLPARL-------AAAE 90
Cdd:PLN02727  747 VAC-LGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHyfedFRQDlrqvihgnntldgvyiTLRMRLrceifrnGKAM 825

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  91 PANLRPLemlaLTESGTTTGSLAYndvslLRQTRQAAHigidlngQERVAELIGDGVLVATPAGSTAYNYSAHGPILPLG 170
Cdd:PLN02727  826 PGKVFDV----LNEVVVDRGSNPY-----LSKIECYEH-------DRLITKVQGDGVIVATPTGSTAYSTAAGGSMVHPN 889

                         170
                  ....*....|....*...
gi 1864817253 171 SHTIALTPLAP----YRP 184
Cdd:PLN02727  890 VPCMLFTPICPhslsFRP 907
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 42-184 1.82e-04

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 42.51  E-value: 1.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253  42 LGGDGFLLQALHRYGALGKPVFGMKLGTVGFlMNQFRD----DDLPARLAAAEPANLRP------LEMLALTESGTTTGS 111
Cdd:PLN02935  269 LGGDGTVLWAASMFKGPVPPVVPFSMGSLGF-MTPFHSeqyrDCLDAILKGPISITLRHrlqchiIRDAAKNEYETEEPI 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1864817253 112 LAYNDVSLLRqtrqaahiGID--LNGQE------RVAELIGDGVLVATPAGSTAYNYSAHGPILPLGSHTIALTPLAP-- 181
Cdd:PLN02935  348 LVLNEVTIDR--------GISsfLTNLEcycdnsFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPhs 419


                  ....*
gi 1864817253 182 --YRP 184
Cdd:PLN02935  420 lsFRP 424
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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