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Conserved domains on  [gi|1861003550|ref|WP_175856274|]
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ABC transporter permease subunit, partial [Burkholderia cepacia]

Protein Classification

ABC transporter permease( domain architecture ID 30)

ABC transporter permease is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TM_PBP2 super family cl00427
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 1-139 2.31e-60

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


The actual alignment was detected with superfamily member PRK10592:

Pssm-ID: 444901  Cd Length: 281  Bit Score: 187.37  E-value: 2.31e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   1 GRFKGFTLYTGMINAPLVIPEVIQGISLLLLFVALEQMFGWPKGRGMVTIWIGHVMLCVSYVAIIVQSRVKEMNKSLEEA 80
Cdd:PRK10592   94 GRFRGSNGFAFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVISSRLRELDRSIEEA 173

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1861003550  81 ALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPGSTTLPLVVFS 139
Cdd:PRK10592  174 AMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFVSGPGATTLPMLVFS 232
 
Name Accession Description Interval E-value
PRK10592 PRK10592
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 1-139 2.31e-60

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182574  Cd Length: 281  Bit Score: 187.37  E-value: 2.31e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   1 GRFKGFTLYTGMINAPLVIPEVIQGISLLLLFVALEQMFGWPKGRGMVTIWIGHVMLCVSYVAIIVQSRVKEMNKSLEEA 80
Cdd:PRK10592   94 GRFRGSNGFAFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVISSRLRELDRSIEEA 173

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1861003550  81 ALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPGSTTLPLVVFS 139
Cdd:PRK10592  174 AMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFVSGPGATTLPMLVFS 232
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 2-139 1.65e-45

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 148.72  E-value: 1.65e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLFVALEQmfgwpkGRGMVTIWIGHVMLCVSYVAIIVQSRVKEMNKSLEEAA 81
Cdd:COG1177    92 RFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGL------SGGLWGLILAHVVFTLPFVVLVVLARLQGFDPSLEEAA 165

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1861003550  82 LDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPGSTTLPLVVFS 139
Cdd:COG1177   166 RDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGVTTLPVYIYS 223
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 2-135 3.38e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 55.36  E-value: 3.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLFVALEQMFGWPkGRGMVTIWIGHVMLcVSYVAIIVQSRVKEMNKSLEEAA 81
Cdd:cd06261    30 RGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILP-GLGLPALILALLLI-APFARLIRRAALESIPKDLVEAA 107

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1861003550  82 LDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPGSTTLPL 135
Cdd:cd06261   108 RALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGT 161
3a0106s02 TIGR00969
sulfate ABC transporter, permease protein; This model describes a subfamily of both CysT and ...
 2-138 3.42e-10

sulfate ABC transporter, permease protein; This model describes a subfamily of both CysT and CysW, paralogous and generally tandemly encoded permease proteins of the sulfate ABC transporter. [Transport and binding proteins, Anions]


Pssm-ID: 273370  Cd Length: 271  Bit Score: 56.21  E-value: 3.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLF------------VALEQMFGWPkgrGMVtiwIGHVMLCVSYVAIIVQSR 69
Cdd:TIGR00969  91 QFPGRKLLDALIDLPFALSPVVAGLTLALLYgsngwlgswlasFGIQIIFTWP---GMA---LAMIFVSLPFVVREVQPV 164

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1861003550  70 VKEMNKSLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSG--PGST-TLPLVVF 138
Cdd:TIGR00969 165 LEELGTEAEEAAATLGASGWQTFWRVTLPSIRWALLYGVVLTFARALGEFGAVVVVSGniPGKTlTLPLLIE 236
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 2-125 2.45e-04

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 39.20  E-value: 2.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIqgISLLLLFVALEQMFGWpkgrGMVTIWIGHVMLCVSYVAIIVQSRVKEMNKSLEEAA 81
Cdd:pfam00528  13 GRRLDRLLRPLIDLLQALPSFV--LAILLVVIAILSILGH----GILPAIILALLGWAGYARLIRRAALRSLPSDLVEAA 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1861003550  82 LDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFL 125
Cdd:pfam00528  87 RALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL 130
 
Name Accession Description Interval E-value
PRK10592 PRK10592
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 1-139 2.31e-60

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182574  Cd Length: 281  Bit Score: 187.37  E-value: 2.31e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   1 GRFKGFTLYTGMINAPLVIPEVIQGISLLLLFVALEQMFGWPKGRGMVTIWIGHVMLCVSYVAIIVQSRVKEMNKSLEEA 80
Cdd:PRK10592   94 GRFRGSNGFAFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVISSRLRELDRSIEEA 173

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1861003550  81 ALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPGSTTLPLVVFS 139
Cdd:PRK10592  174 AMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFVSGPGATTLPMLVFS 232
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 2-139 1.65e-45

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 148.72  E-value: 1.65e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLFVALEQmfgwpkGRGMVTIWIGHVMLCVSYVAIIVQSRVKEMNKSLEEAA 81
Cdd:COG1177    92 RFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGL------SGGLWGLILAHVVFTLPFVVLVVLARLQGFDPSLEEAA 165

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1861003550  82 LDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPGSTTLPLVVFS 139
Cdd:COG1177   166 RDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGVTTLPVYIYS 223
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 2-139 7.27e-30

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 108.15  E-value: 7.27e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLFVALEQMFGWpkgrgmVTIWIGHVMLCVSYVAIIVQSRVKEMNKSLEEAA 81
Cdd:PRK09500   88 RFRGKKFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGF------WSLLFAHITFCLPFVVVTVYSRLKGFDVRMLEAA 161

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1861003550  82 LDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPGSTTLPLVVFS 139
Cdd:PRK09500  162 KDLGASEFTILRKIILPLALPAVAAGWLLSFTLSLDDVVVSSFVTGPSYEILPLKIYS 219
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
1-139 5.41e-17

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 75.97  E-value: 5.41e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   1 GRFKGFTLYTGMInaPLVIPEVIQGISLLLLFVALeqmFGWPKGRGMVTIWIGHVMLCVSYVAIIVQSRVKEMNKSLEEA 80
Cdd:COG1178   370 GRLARLLDRLAML--PYAVPGIVLGLGLLLLFNRP---LPLLLYGTLAILVLAYVVRFLPFALRSLEAALAQIDPSLEEA 444

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1861003550  81 ALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPGSTTLPLVVFS 139
Cdd:COG1178   445 ARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPGFETLAVLIYQ 503
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
2-139 1.17e-15

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 72.12  E-value: 1.17e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLF-------VALEQMFGWPKG--RGMVTIWIGHVMLCVSYVAIIVQSRVKE 72
Cdd:COG1178    85 DFPGRRLLRWLLLLPLALPPYVVALAWIALFgpngllnTLLRALFGLEPPdiYGLGGIILVLVLFNYPYVYLLLRAALRS 164

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1861003550  73 MNKSLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLsGPGSTTLPLVVFS 139
Cdd:COG1178   165 IDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVL-GGGYTTLTTAIYQ 230
modB PRK09421
molybdate ABC transporter permease subunit;
1-139 1.39e-11

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 59.55  E-value: 1.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   1 GRFKGFTLYTGMINAPLVIPEVIQGISLLLLF-------VALEQMFGWPKGRGmvtiWIGHVMLC-VSYVAIIVQS---R 69
Cdd:PRK09421   39 CRFPGKSLLDSLLHLPLVLPPVVTGYLLLISMgrrgfigQWLYEWFGISFAFS----WRGAALAAaVMAFPLMVRAirlS 114

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1861003550  70 VKEMNKSLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLS-AFLSG-PGST-TLPLVVFS 139
Cdd:PRK09421  115 LEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAFARSLGEFGATiTFVSNiPGETqTIPSAMYT 187
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 2-139 1.56e-11

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 59.76  E-value: 1.56e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLFV------ALEQMFGWPKGRGMVTIWIGHVMLCVSYVAIIVQSRVKEMNK 75
Cdd:COG0555    85 RFPGKRLVDALVDLPFALPTAVAGIALLLLFGpngwlgQLLAPLGIKVAFTPLGIVLAQTFVSLPFVVRTVQPVLEELDP 164

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1861003550  76 SLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSG--PGST-TLPLVVFS 139
Cdd:COG0555   165 ELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAFARALGEFGAVIFIAGnlPMKTeILPLLIYL 231
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 2-135 3.38e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 55.36  E-value: 3.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLFVALEQMFGWPkGRGMVTIWIGHVMLcVSYVAIIVQSRVKEMNKSLEEAA 81
Cdd:cd06261    30 RGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILP-GLGLPALILALLLI-APFARLIRRAALESIPKDLVEAA 107

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1861003550  82 LDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPGSTTLPL 135
Cdd:cd06261   108 RALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGT 161
3a0106s02 TIGR00969
sulfate ABC transporter, permease protein; This model describes a subfamily of both CysT and ...
 2-138 3.42e-10

sulfate ABC transporter, permease protein; This model describes a subfamily of both CysT and CysW, paralogous and generally tandemly encoded permease proteins of the sulfate ABC transporter. [Transport and binding proteins, Anions]


Pssm-ID: 273370  Cd Length: 271  Bit Score: 56.21  E-value: 3.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLF------------VALEQMFGWPkgrGMVtiwIGHVMLCVSYVAIIVQSR 69
Cdd:TIGR00969  91 QFPGRKLLDALIDLPFALSPVVAGLTLALLYgsngwlgswlasFGIQIIFTWP---GMA---LAMIFVSLPFVVREVQPV 164

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1861003550  70 VKEMNKSLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSG--PGST-TLPLVVF 138
Cdd:TIGR00969 165 LEELGTEAEEAAATLGASGWQTFWRVTLPSIRWALLYGVVLTFARALGEFGAVVVVSGniPGKTlTLPLLIE 236
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 73-139 4.53e-10

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 55.92  E-value: 4.53e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1861003550  73 MNKSLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPGSTTLPLVVFS 139
Cdd:COG1176   180 IDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQ 246
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 1-112 1.08e-09

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 54.28  E-value: 1.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   1 GRFKGFTLYTGMINAPLVIPEVIQGISLLLLFV-------ALEQMFGWPkgrgMVTIWIGHVMLCVSY----VAIIVQSR 69
Cdd:COG4149    37 TRFRGKGLLEALVTLPLVLPPTVLGFYLLLLFGrngplgqLLEELFGIS----LVFTWTGAVLASVVVslplMVQPLRAA 112

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1861003550  70 VKEMNKSLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSF 112
Cdd:COG4149   113 FEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAVLAF 155
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
2-127 5.38e-09

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 52.83  E-value: 5.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLFVALEQMFGWPKGRGM--VTIWIG----HVMLCVSYVAIIVQSRVKEMNK 75
Cdd:PRK10971   89 RFPGRTLLDALMDLPFALPTAVAGLTLASLFSVNGWYGEWLAKFDIkvTYTWLGiavaMAFTSIPFVVRTVQPVLEELGP 168

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1861003550  76 SLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSG 127
Cdd:PRK10971  169 EYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSFTRSLGEFGAVIFIAG 220
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 15-118 1.15e-08

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 51.99  E-value: 1.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550  15 APLVIPEVIQGISLLLLFVA---LEQMFGWPKGRGMVTIWIGHVMLCVSYVAIIVQSRVKEMNKSLEEAALDLGATPLKV 91
Cdd:TIGR03262  98 LPLLAPSLLPAISLIYLFGNqglLKGLLGGFSIYGFWGIVIGEVFYTFPHALMILVTALSLADGRLYEAARAMGASPWRT 177

                          90       100
                  ....*....|....*....|....*..
gi 1861003550  92 FFVVTLPLISQALLSGWLLSFTLSIDD 118
Cdd:TIGR03262 178 FFTVTLPGAKYGLISAAFVVFTLVITD 204
cysT CHL00187
sulfate transport protein; Provisional
 2-116 9.22e-08

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 48.86  E-value: 9.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLFVALEQMFGWPKGRGMVTIW----IGHVMLCVS--YVAIIVQSRVKEMNK 75
Cdd:CHL00187   86 NFPGKRLLDAAVDLPFALPTSVAGLTLATVYGDNGWIGHLLSHLGIQIVFtklgVLLAMIFVSfpFVVRTIQPVLQEIEK 165

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1861003550  76 SLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSI 116
Cdd:CHL00187  166 ELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAI 206
PRK10683 PRK10683
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 50-130 2.53e-07

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182646  Cd Length: 317  Bit Score: 48.17  E-value: 2.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550  50 IWIGHVMLCVSYVAIIVQSRVKEMNKSLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPG 129
Cdd:PRK10683  187 VYIGIVYAYLPFMVLPIYTALTRIDYSLVEAALDLGARPLKTFFSVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPD 266


                  .
gi 1861003550 130 S 130
Cdd:PRK10683  267 S 267
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
2-138 1.54e-05

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 42.81  E-value: 1.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLF-------VALEQMFGWP-------KGRGMVTIWIGHVMLCVSYVAIIVQ 67
Cdd:COG1175   106 KLRGRGFFRTLFFLPWVISPVVVALIWKWLFnpdygllNALLGALGLEpinwlgdPSLALPAVIIVTVWKGTGFNMLIFL 185

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1861003550  68 SRVKEMNKSLEEAA-LDlGATPLKVFFVVTLPLISQALLSGWLLSF--TLSIDDLVLSAFLSGPGSTTLPLVVF 138
Cdd:COG1175   186 AGLQSIPRELYEAArID-GASPWQRFRRITLPLLRPTILFVLVLSTigALQVFDLVYVLTGGGPGNSTTTLVLY 258
YnjC COG4135
ABC-type uncharacterized transport system YnjBCD, permease component [General function ...
 16-116 5.99e-05

ABC-type uncharacterized transport system YnjBCD, permease component [General function prediction only];


Pssm-ID: 443310 [Multi-domain]  Cd Length: 564  Bit Score: 41.39  E-value: 5.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550  16 PLVIPEV--IQGISLLLLFVALEQMFGWpkgrgmvTIWiGHVMLCVSYVAIIVQSRVKEMNKSLEEAALDLGATPLKVFF 93
Cdd:COG4135   401 PLLVPQIafLFGLQVLLLRLGLDGTWLA-------VIW-AHLVFVLPYVFLSLAGPWRALDPRYAQVAASLGASPWRVFW 472

                          90       100
                  ....*....|....*....|...
gi 1861003550  94 VVTLPLISQALLSGWLLSFTLSI 116
Cdd:COG4135   473 RVKLPLLLRPILTAAAVGFAVSV 495
cysW PRK11602
sulfate/thiosulfate ABC transporter permease CysW;
2-137 8.50e-05

sulfate/thiosulfate ABC transporter permease CysW;


Pssm-ID: 183225  Cd Length: 283  Bit Score: 40.89  E-value: 8.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLFVA------------LEQMFGWPkGRGMVTIWIGHVMLCVSYVAIIVQSR 69
Cdd:PRK11602   95 NFPGRQLLLTLLDIPFAVSPVVAGLVYLLFYGSngplggwldehnLQLMFSWP-GMVLVTIFVTCPFVVRELVPVMLSQG 173

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1861003550  70 VKEmnkslEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGP--GST-TLPLVV 137
Cdd:PRK11602  174 SQE-----DEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSirGETlSLPLQI 239
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 2-125 2.45e-04

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 39.20  E-value: 2.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIqgISLLLLFVALEQMFGWpkgrGMVTIWIGHVMLCVSYVAIIVQSRVKEMNKSLEEAA 81
Cdd:pfam00528  13 GRRLDRLLRPLIDLLQALPSFV--LAILLVVIAILSILGH----GILPAIILALLGWAGYARLIRRAALRSLPSDLVEAA 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1861003550  82 LDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFL 125
Cdd:pfam00528  87 RALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL 130
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 75-139 2.50e-04

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 39.36  E-value: 2.50e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1861003550  75 KSLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVL-SAFLSGPGSTTLPLVVFS 139
Cdd:COG3833   171 KELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILaSVLLRSPENYTLAVGLYS 236
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 2-139 2.49e-03

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 36.61  E-value: 2.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   2 RFKGFTLYTGMINAPLVIPEVIQGISLLLLFVALeqmfgwpkgrGMV----TIWIGHVMLCVSYVAIIVQSRVKEMNKSL 77
Cdd:COG0395   105 RFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQL----------GLLntywGLILPYLAFGLPFGIFLLRQFFRSIPREL 174

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1861003550  78 EEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLS-AFLSGPGSTTLPLVVFS 139
Cdd:COG0395   175 EEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPlILLTSPDLRTLPVGLAS 237
malF PRK10999
maltose ABC transporter permease MalF;
6-132 4.19e-03

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 36.09  E-value: 4.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550   6 FTLYTGMINAPLVIPEVIQG-----------------ISLLL---LF--------VALEQMFG----W---P-KGRGMVT 49
Cdd:PRK10999  300 LTVAVGMVLACLVQWEALKGkavyrvllilpyavpsfISILIfkgLFnqsfgeinMMLSALFGikpaWfsdPtLAKTMIL 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1861003550  50 I---WIGHvmlcvSYVAIIVQSRVKEMNKSLEEA-ALDlGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFL 125
Cdd:PRK10999  380 IvntWLGY-----PYMMILCMGLLKAIPDDLYEAsAMD-GAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLL 453

                         170
                  ....*....|..
gi 1861003550 126 S--GP---GSTT 132
Cdd:PRK10999  454 TngGPdmiGTTT 465
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 75-139 9.95e-03

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 34.59  E-value: 9.95e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1861003550  75 KSLEEAALDLGATPLKVFFVVTLPLISQALLSGWLLSFTLSIDDLVLSAFLSGPGSTTLPLVVFS 139
Cdd:PRK15050  189 ARQLEAAASLGASPWRVARRVILPEAWPALAAGGSLCLLLTLNEFGIVLFTGAKDVVTLPVLIYS 253
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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