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Conserved domains on  [gi|1859508042|ref|WP_175187019|]
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protein translocase subunit SecD [Prosthecochloris ethylica]

Protein Classification

preprotein translocase subunit SecD( domain architecture ID 11481672)

preprotein translocase subunit SecD is part of the Sec protein translocase complex; interacts with the SecYEG preprotein conducting channel

Gene Ontology:  GO:0015450|GO:0043952|GO:0065002
PubMed:  16452406|20444093

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
secD PRK05812
preprotein translocase subunit SecD; Reviewed
 6-587 0e+00

preprotein translocase subunit SecD; Reviewed


:

Pssm-ID: 235615 [Multi-domain]  Cd Length: 462  Bit Score: 549.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042   6 FTAFLIVALTALALWSLWPTYQEYSYNKQlsrfsssedslafvqehRESLDNARAKSLKLGLDLKGGMYLVLEVDLIDLL 85
Cdd:PRK05812    1 WKYLLILLVLLIGLLYALPNLRGALAPAT-----------------PEWLPALGAKPMKLGLDLRGGVHFLLEVDMDDAL 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  86 DQRAWNKDEQFRDILATVKERASDSGARIIDLLAGEFSRQGIRLSRYFYDvrdtdeeviAKLRDEAEEALSRAREIIRNR 165
Cdd:PRK05812   64 KKRLESLADDLRSLLREKKIRYGGVEITFRDAEDRDKAIALLRKLSSLTE---------AELKEITEEALEQAIEIIRNR 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 166 VDQYGVAEPQIQVQGARRIIVALPGVSDQERIRKLLRGTAKLEFKLVRdreamlaglerinaaleedvesgseagedtvd 245
Cdd:PRK05812  135 VNELGVAEPVIQRQGADRIVVELPGVQDTARAKEILGKTATLEFRLVP-------------------------------- 182

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 246 vpanplfehmtvmengrvyvpqysrdyllslfqrddiarllpkdtefrmsartiegqdgtqfhdlyllkktPELTGNVIT 325
Cdd:PRK05812  183 -----------------------------------------------------------------------VILTGDDIT 191

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 326 EAKATFGASAmQPEVTMKMNAEGTSKWARITGANIGRQIAIVLDGAVYSAPVVESKIPGGSSVINGIESLEEAQDLEIVL 405
Cdd:PRK05812  192 DASASFDQQG-QPVVNITLDSEGAKKFADITKANIGKRMAIVLDGEVISAPVIQSAITGGSAQITGNFTAEEARDLALLL 270

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 406 KAGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYRKAGISADLALVLNILFVLSVLAGFGAALTLP 485
Cdd:PRK05812  271 RAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYYRLFGLIANIALVANLVLILAVLSLLGATLTLP 350

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 486 GIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIG 565
Cdd:PRK05812  351 GIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTILDSNITTLIAAIILYALGTGPVKGFAVTLGIG 430

                         570       580
                  ....*....|....*....|..
gi 1859508042 566 TAASLFTALVVTKAIFDLLISK 587
Cdd:PRK05812  431 ILTSMFTAITVTRALVNLLYGR 452
 
Name Accession Description Interval E-value
secD PRK05812
preprotein translocase subunit SecD; Reviewed
 6-587 0e+00

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 235615 [Multi-domain]  Cd Length: 462  Bit Score: 549.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042   6 FTAFLIVALTALALWSLWPTYQEYSYNKQlsrfsssedslafvqehRESLDNARAKSLKLGLDLKGGMYLVLEVDLIDLL 85
Cdd:PRK05812    1 WKYLLILLVLLIGLLYALPNLRGALAPAT-----------------PEWLPALGAKPMKLGLDLRGGVHFLLEVDMDDAL 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  86 DQRAWNKDEQFRDILATVKERASDSGARIIDLLAGEFSRQGIRLSRYFYDvrdtdeeviAKLRDEAEEALSRAREIIRNR 165
Cdd:PRK05812   64 KKRLESLADDLRSLLREKKIRYGGVEITFRDAEDRDKAIALLRKLSSLTE---------AELKEITEEALEQAIEIIRNR 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 166 VDQYGVAEPQIQVQGARRIIVALPGVSDQERIRKLLRGTAKLEFKLVRdreamlaglerinaaleedvesgseagedtvd 245
Cdd:PRK05812  135 VNELGVAEPVIQRQGADRIVVELPGVQDTARAKEILGKTATLEFRLVP-------------------------------- 182

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 246 vpanplfehmtvmengrvyvpqysrdyllslfqrddiarllpkdtefrmsartiegqdgtqfhdlyllkktPELTGNVIT 325
Cdd:PRK05812  183 -----------------------------------------------------------------------VILTGDDIT 191

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 326 EAKATFGASAmQPEVTMKMNAEGTSKWARITGANIGRQIAIVLDGAVYSAPVVESKIPGGSSVINGIESLEEAQDLEIVL 405
Cdd:PRK05812  192 DASASFDQQG-QPVVNITLDSEGAKKFADITKANIGKRMAIVLDGEVISAPVIQSAITGGSAQITGNFTAEEARDLALLL 270

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 406 KAGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYRKAGISADLALVLNILFVLSVLAGFGAALTLP 485
Cdd:PRK05812  271 RAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYYRLFGLIANIALVANLVLILAVLSLLGATLTLP 350

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 486 GIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIG 565
Cdd:PRK05812  351 GIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTILDSNITTLIAAIILYALGTGPVKGFAVTLGIG 430

                         570       580
                  ....*....|....*....|..
gi 1859508042 566 TAASLFTALVVTKAIFDLLISK 587
Cdd:PRK05812  431 ILTSMFTAITVTRALVNLLYGR 452
SecD COG0342
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ...
 57-592 1.55e-166

Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440111 [Multi-domain]  Cd Length: 434  Bit Score: 481.15  E-value: 1.55e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  57 NARAKSLKLGLDLKGGMYLVLEVDLIDLLDQRAwnkdeqfrdilatvkerasdsgariidllagefsrqgirlsryfydv 136
Cdd:COG0342    25 NGPAKPIKLGLDLQGGVHLLLEVDTDAALDEDG----------------------------------------------- 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 137 rdtdeeviAKLRDEAEEALSRAREIIRNRVDQYGVAEPQIQVQGARRIIVALPGVSDQERIRKLLRGTAKLEFKLVRDRe 216
Cdd:COG0342    58 --------DGIREVTEEALDQAIEILRNRVNELGVSEPVIQRQGDDRIVVELPGVQDPAEAKELLGKTAKLEFRLVDDS- 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 217 amlaglerinaaleedvesgseagedtvdvpanplfehmtvmengrvyvpqysrdyllslfqrDDIARLLPKDTEfrmsa 296
Cdd:COG0342   129 ---------------------------------------------------------------ADAQAAVPAGSE----- 140

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 297 rTIEGQDGTQfhdlYLLKKTPELTGNVITEAKATFGASAMQPEVTMKMNAEGTSKWARITGANIGRQIAIVLDGAVYSAP 376
Cdd:COG0342   141 -LLPCRDGQP----YLLLGPVVLTGDDLTDASAGFDQQTGQPVVSFTLDSEGAKKFADATRENVGKPLAIVLDGEVISAP 215

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 377 VVESKIPGGSSVINGIESLEEAQDLEIVLKAGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYRKA 456
Cdd:COG0342   216 VIQEPITGGSAQITGSFTVEEAQDLALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLP 295

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 457 GISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDS 536
Cdd:COG0342   296 GLVANIALALNVVLLLGVLSLLGATLTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILDA 375

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1859508042 537 QITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAIFDLLISKNLLTE 592
Cdd:COG0342   376 NVTTLIAAVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKK 431
secD TIGR01129
protein-export membrane protein SecD; Members of this family are highly variable in length ...
 130-581 7.81e-140

protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273456 [Multi-domain]  Cd Length: 397  Bit Score: 411.68  E-value: 7.81e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 130 SRYFYDVrDTDEEVIAKLRDEA-----EEALSRAREIIRNRVDQYGVAEPQIQVQGARRIIVALPGVSDQERIRKLLRGT 204
Cdd:TIGR01129   9 ARVLLEV-DMSTAVVLKLSEAEvnairKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGVTDTSRAKDILGGT 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 205 AKLEFKLVRDREAMLAglerinAALEEDVESGSEagedtvdvpanplfehmtvmengrvyvpqysrdyLLSLFQRDdiar 284
Cdd:TIGR01129  88 ATLEFRLVDDESTSPD------DALAGNVPAGSE----------------------------------LLDSRSGD---- 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 285 llpkdtefrmsartiegqdgtqfHDLYLLKKTPELTGNVITEAKATFGASAMQPEVTMKMNAEGTSKWARITGANIGRQI 364
Cdd:TIGR01129 124 -----------------------PKYYLLKKSPVLTGDHITDATSSVDQRSGQPVVSFSLDSEGARIFGDFTQANIGKRL 180

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 365 AIVLDGAVYSAPVVESKIPGGSSVINGIESLEEAQDLEIVLKAGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFI 444
Cdd:TIGR01129 181 AIVLDNKVVSAPTIQEAITGGSGQITGNFTAEEANDLALVLRSGALPAPLQILEERTIGPSLGADSIEAGIKAGLIGLVL 260

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 445 VAVFMIFYYRKAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVET 524
Cdd:TIGR01129 261 VLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEELRLGKSVRQAIEA 340

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1859508042 525 GYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAIF 581
Cdd:TIGR01129 341 GFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFTRLLL 397
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 416-580 5.72e-18

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 82.27  E-value: 5.72e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 416 IIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYR-KAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTI 494
Cdd:pfam02355  15 IISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEwRFALGAIIALAHDVIITVGVFSLFGIEVDLATVAALLTII 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 495 GMAVDANVLIFERIREEIGQKK--NLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFT 572
Cdd:pfam02355  95 GYSVNDTVVVFDRVRENLRKKTraTLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALLVGVIVGTYS 174


                  ....*...
gi 1859508042 573 ALVVTKAI 580
Cdd:pfam02355 175 SIFIASPI 182
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 442-593 2.23e-13

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 73.66  E-value: 2.23e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  442 LFIVA----VFMIFYYRKAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKK- 516
Cdd:NF037998   451 LLILAiaimIYLLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYKNKr 530

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1859508042  517 NLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAIFDLLISKNLLTER 593
Cdd:NF037998   531 SIEESFKIANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVARLMIWLTIKLQWFKKY 607
 
Name Accession Description Interval E-value
secD PRK05812
preprotein translocase subunit SecD; Reviewed
 6-587 0e+00

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 235615 [Multi-domain]  Cd Length: 462  Bit Score: 549.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042   6 FTAFLIVALTALALWSLWPTYQEYSYNKQlsrfsssedslafvqehRESLDNARAKSLKLGLDLKGGMYLVLEVDLIDLL 85
Cdd:PRK05812    1 WKYLLILLVLLIGLLYALPNLRGALAPAT-----------------PEWLPALGAKPMKLGLDLRGGVHFLLEVDMDDAL 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  86 DQRAWNKDEQFRDILATVKERASDSGARIIDLLAGEFSRQGIRLSRYFYDvrdtdeeviAKLRDEAEEALSRAREIIRNR 165
Cdd:PRK05812   64 KKRLESLADDLRSLLREKKIRYGGVEITFRDAEDRDKAIALLRKLSSLTE---------AELKEITEEALEQAIEIIRNR 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 166 VDQYGVAEPQIQVQGARRIIVALPGVSDQERIRKLLRGTAKLEFKLVRdreamlaglerinaaleedvesgseagedtvd 245
Cdd:PRK05812  135 VNELGVAEPVIQRQGADRIVVELPGVQDTARAKEILGKTATLEFRLVP-------------------------------- 182

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 246 vpanplfehmtvmengrvyvpqysrdyllslfqrddiarllpkdtefrmsartiegqdgtqfhdlyllkktPELTGNVIT 325
Cdd:PRK05812  183 -----------------------------------------------------------------------VILTGDDIT 191

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 326 EAKATFGASAmQPEVTMKMNAEGTSKWARITGANIGRQIAIVLDGAVYSAPVVESKIPGGSSVINGIESLEEAQDLEIVL 405
Cdd:PRK05812  192 DASASFDQQG-QPVVNITLDSEGAKKFADITKANIGKRMAIVLDGEVISAPVIQSAITGGSAQITGNFTAEEARDLALLL 270

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 406 KAGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYRKAGISADLALVLNILFVLSVLAGFGAALTLP 485
Cdd:PRK05812  271 RAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYYRLFGLIANIALVANLVLILAVLSLLGATLTLP 350

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 486 GIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIG 565
Cdd:PRK05812  351 GIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTILDSNITTLIAAIILYALGTGPVKGFAVTLGIG 430

                         570       580
                  ....*....|....*....|..
gi 1859508042 566 TAASLFTALVVTKAIFDLLISK 587
Cdd:PRK05812  431 ILTSMFTAITVTRALVNLLYGR 452
SecD COG0342
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ...
 57-592 1.55e-166

Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440111 [Multi-domain]  Cd Length: 434  Bit Score: 481.15  E-value: 1.55e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  57 NARAKSLKLGLDLKGGMYLVLEVDLIDLLDQRAwnkdeqfrdilatvkerasdsgariidllagefsrqgirlsryfydv 136
Cdd:COG0342    25 NGPAKPIKLGLDLQGGVHLLLEVDTDAALDEDG----------------------------------------------- 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 137 rdtdeeviAKLRDEAEEALSRAREIIRNRVDQYGVAEPQIQVQGARRIIVALPGVSDQERIRKLLRGTAKLEFKLVRDRe 216
Cdd:COG0342    58 --------DGIREVTEEALDQAIEILRNRVNELGVSEPVIQRQGDDRIVVELPGVQDPAEAKELLGKTAKLEFRLVDDS- 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 217 amlaglerinaaleedvesgseagedtvdvpanplfehmtvmengrvyvpqysrdyllslfqrDDIARLLPKDTEfrmsa 296
Cdd:COG0342   129 ---------------------------------------------------------------ADAQAAVPAGSE----- 140

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 297 rTIEGQDGTQfhdlYLLKKTPELTGNVITEAKATFGASAMQPEVTMKMNAEGTSKWARITGANIGRQIAIVLDGAVYSAP 376
Cdd:COG0342   141 -LLPCRDGQP----YLLLGPVVLTGDDLTDASAGFDQQTGQPVVSFTLDSEGAKKFADATRENVGKPLAIVLDGEVISAP 215

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 377 VVESKIPGGSSVINGIESLEEAQDLEIVLKAGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYRKA 456
Cdd:COG0342   216 VIQEPITGGSAQITGSFTVEEAQDLALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYRLP 295

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 457 GISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDS 536
Cdd:COG0342   296 GLVANIALALNVVLLLGVLSLLGATLTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTILDA 375

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1859508042 537 QITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAIFDLLISKNLLTE 592
Cdd:COG0342   376 NVTTLIAAVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKK 431
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 1-588 5.71e-151

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 452.76  E-value: 5.71e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042   1 MKNKRFTAFLIVALTALALWSLWPTYQeysynkqlsrfsssedslafvqehresldnarAKSLKLGLDLKGGMYLVLEVD 80
Cdd:PRK13024    1 MRNKRWVIFFLTLLLLIGIYYASPKFV--------------------------------TKNINLGLDLQGGFEVLLEVS 48

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  81 LIDLLDQRAwnkdeqfrdilatvkerasdsgariidllagefsrqgirlsryfydvrdtdeeviaklrdeaEEALSRARE 160
Cdd:PRK13024   49 PADKGKKAD--------------------------------------------------------------REALDSTVE 66

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 161 IIRNRVDQYGVAEPQIQVQGARRIIVALPGVSDQERIRKLLRGTAKLEFKLVRDREAMLAGLERInaaleedvesGSEAG 240
Cdd:PRK13024   67 VLRNRIDGLGVSEPNIQREGNNRIRVELPGVQDPERARELLGSTAKLTFRDVTDPPPPGVGGPVV----------GPDEG 136

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 241 EDTVDVpaNPLFehmtvmengrvyvpqysrdyllslfqrddiarllpkdtefrmsartiegqdgtqfhdlyllkktpeLT 320
Cdd:PRK13024  137 KDTAVL--NPVL------------------------------------------------------------------LS 148

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 321 GNVITEAKATFGASAM-QPEVTMKMNAEGTSKWARITGANI-----GRQIAIVLDGAVYSAPVVESKIPGGSSVINGIES 394
Cdd:PRK13024  149 GDDLTDAGAKFDQDQTnRPSVSLKLKSEGAKKWAKVTEKNSkkgppNNRIAIVLDPKVISAPTVNQPINGGSVQISGNFT 228

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 395 LEEAQDLEIVLKAGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYRKAGISADLALVLNILFVLSV 474
Cdd:PRK13024  229 VEEAKDLANLLNAGALPAPLKIIESRSVGPTLGQDAIDAGIIAGIIGFALIFLFMLVYYGLPGLIANIALLLYIFLTLGA 308

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 475 LAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGP 554
Cdd:PRK13024  309 LSSLGAVLTLPGIAGLVLGIGMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILDSNITTLIAAAILFFFGTGP 388

                         570       580       590
                  ....*....|....*....|....*....|....
gi 1859508042 555 IQGFAVTLMIGTAASLFTALVVTKAIFDLLISKN 588
Cdd:PRK13024  389 VKGFATTLIIGILASLFTAVFLTRLLLELLVKRG 422
secD TIGR01129
protein-export membrane protein SecD; Members of this family are highly variable in length ...
 130-581 7.81e-140

protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273456 [Multi-domain]  Cd Length: 397  Bit Score: 411.68  E-value: 7.81e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 130 SRYFYDVrDTDEEVIAKLRDEA-----EEALSRAREIIRNRVDQYGVAEPQIQVQGARRIIVALPGVSDQERIRKLLRGT 204
Cdd:TIGR01129   9 ARVLLEV-DMSTAVVLKLSEAEvnairKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGVTDTSRAKDILGGT 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 205 AKLEFKLVRDREAMLAglerinAALEEDVESGSEagedtvdvpanplfehmtvmengrvyvpqysrdyLLSLFQRDdiar 284
Cdd:TIGR01129  88 ATLEFRLVDDESTSPD------DALAGNVPAGSE----------------------------------LLDSRSGD---- 123

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 285 llpkdtefrmsartiegqdgtqfHDLYLLKKTPELTGNVITEAKATFGASAMQPEVTMKMNAEGTSKWARITGANIGRQI 364
Cdd:TIGR01129 124 -----------------------PKYYLLKKSPVLTGDHITDATSSVDQRSGQPVVSFSLDSEGARIFGDFTQANIGKRL 180

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 365 AIVLDGAVYSAPVVESKIPGGSSVINGIESLEEAQDLEIVLKAGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFI 444
Cdd:TIGR01129 181 AIVLDNKVVSAPTIQEAITGGSGQITGNFTAEEANDLALVLRSGALPAPLQILEERTIGPSLGADSIEAGIKAGLIGLVL 260

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 445 VAVFMIFYYRKAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVET 524
Cdd:TIGR01129 261 VLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEELRLGKSVRQAIEA 340

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1859508042 525 GYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAIF 581
Cdd:TIGR01129 341 GFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGIIASLFTALVFTRLLL 397
PRK14726 PRK14726
protein translocase subunit SecDF;
47-581 1.91e-99

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 321.28  E-value: 1.91e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  47 FVQEHRESLDN-ARAKSLKLGLDLKGGMYLVLEVDLIDLLDQRAWNKDEQFRDILATVKER---ASDSG----ARIID-- 116
Cdd:PRK14726   28 LSEAQLASLPSwLPHRQVTLGLDLQGGSHIVLKVERSDIVKDRLEETVANIRNALRDAGIRytgLTGNGqtvqVRITDpa 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 117 ---------------LLAGEFSRQGIRLSRY------FYDVRDTDEEVIAKLRDeaeeALSRAREIIRNRVDQYGVAEPQ 175
Cdd:PRK14726  108 qtqaavdalkpltapVSAGGLGGSSIQELTLqeggegQLRLQLTDAGIDYRVSS----ALTQSIEVVRRRVAELGTTEPL 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 176 IQVQGARRIIVALPGVSDQERIRKLLRGTAKLEFKLVRdrEAMLAgleriNAALEEDVESGSEAgedtvdvpanplfehm 255
Cdd:PRK14726  184 IRRQGDDRIVVQVPGLVDPQRLKNLLNQPAKLSFRLVD--SSMPA-----QEALNGRPPATSEV---------------- 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 256 tvmengrvyvpqysrdyllsLFQRDDIArlLPkdtefrmsartiegqdgtqfhdlYLLKKTPELTGNVITEAKATFGASA 335
Cdd:PRK14726  241 --------------------LYSLDDPP--VP-----------------------YLVERRAFVSGENLVDAQPVFDPQT 275

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 336 MQPEVTMKMNAEGTSKWARITGANIGRQIAIVLDGAVYSAPVVESKIPGGSSVINGIESLEEAQDLEIVLKAGALPAPVR 415
Cdd:PRK14726  276 NEPVVTFRLDAEGTQRFAQATQQNVGKHFAIVLDGQVISAPVIDEAITGGEGRISGNFSEQGANDLAVLLRAGALPATLT 355

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 416 IIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYRKAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIG 495
Cdd:PRK14726  356 VVEERTVGPGLGADSIAAGLVAGLIAAILVAALMIGFYGFLGVIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIG 435

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 496 MAVDANVLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALV 575
Cdd:PRK14726  436 MAVDSNVLIYERIREEEKTGHSLIQALDRGFSRALATIVDANVTILIAAVILFFLGSGAVRGFAVTLAVGILTTVFTAFT 515


                  ....*.
gi 1859508042 576 VTKAIF 581
Cdd:PRK14726  516 LTRSLV 521
secD PRK12933
protein translocase subunit SecD;
63-583 6.63e-77

protein translocase subunit SecD;


Pssm-ID: 183831 [Multi-domain]  Cd Length: 604  Bit Score: 255.38  E-value: 6.63e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  63 LKLGLDLKGGMYLVLEVDlIDLLDQ----------RAWNKDEQFRDilATVKErasDSGARIIDLLAGEFSRQGIR---- 128
Cdd:PRK12933  126 IKLGLDLRGGVQFLLDVD-VDPVYQeqrdalvdsvRQFLREQRIRG--VSVRL---DDSDQLAVTTPDNDARSAVRqfiq 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 129 ----------LSRYFYDVRDTDEEVIaKLRDEAeeaLSRAREIIRNRVDQYGVAEPQIQVQGARRIIVALPGVSDQERIR 198
Cdd:PRK12933  200 qnypgwqvtnSDDRGLQLKLSQQEKT-KFRNLT---VQQNLQIMRSRIEELGITEALVQRQGEHRIRIELPGVQDPAAAK 275

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 199 KLLRGTAKLEFklvrdreamlaglerinaaleedvesgseagedtvdvpanplFEhmtVMENGRVYvpqysrdyllslfq 278
Cdd:PRK12933  276 NVIGATASLAF------------------------------------------YE---VKESGSVN-------------- 296

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 279 rddiarllpkdtefrmsARTIEGQDGTQfhdLYLLKKtPELTGNVITEAKATFGASAMqPEVTMKMNAEGTSKWARITGA 358
Cdd:PRK12933  297 -----------------AKVLKDKNGRP---VYVARR-PVLGGEHIVDARASLGEMGM-AEVNISLDRAGGKKMSDFSRD 354

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 359 NIGRQIA-------------IVLDGAVYSAPVVESKIpGGSSVINGIESLEEAQDLEIVLKAGALPAPVRIIEERTVGPS 425
Cdd:PRK12933  355 NIGKPMAtsyseysrdeqgkTKQSEEVISVATIQSQL-GDRFRITGAGSYQEAQQLALLLRAGSLTAPVTIVEERTIGPS 433

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 426 LGSDYIRSGLLSAGWGLFIVAVFMIFYYRKAGISADLALVLNILFVLSVLAGF-GAALTLPGIAGLVLTIGMAVDANVLI 504
Cdd:PRK12933  434 LGAENIENGFAALALGMGITLLFMALWYRRLGWVANVALIANMVCLFGLLALIpGAVLTLPGIAGLVLTVGMAVDTNVLI 513

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1859508042 505 FERIREEIGQKKNLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAIFDL 583
Cdd:PRK12933  514 FERIKDKLKEGRSFAQAIDTGFDSAFSTIFDANFTTMITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGIFASRALINL 592
PRK13023 PRK13023
protein translocase subunit SecDF;
311-578 1.96e-55

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 200.23  E-value: 1.96e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 311 YLLKKTPELTGNVITEAKATFGASAMQPEVTMKMNAEGTSKWARITGANIGRQIAIVLDGAVYSAPVVESKIPGGSSVIN 390
Cdd:PRK13023  157 YLLKKTPILTGHDITDAKASISADDGQPVITLTLDDNGRRRLADLTAQGNENSFAIVVDNQVVSAPTVSGPLDTSELQIE 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 391 GIESLEEAQDLEIVLKAGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYRKAGISADLALVLNILF 470
Cdd:PRK13023  237 GAFDLQAANNMAVVLRSGALPQAVTVLEERTIASALGEDYASAAVLAALLAALVVGLFMVLSYGILGVIALVALVVNIII 316

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 471 VLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVY 550
Cdd:PRK13023  317 LTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAMESGFYRALSTIVDANLTTLIAALVLFLL 396

                         250       260
                  ....*....|....*....|....*...
gi 1859508042 551 GIGPIQGFAVTLMIGTAASLFTALVVTK 578
Cdd:PRK13023  397 GSGTVHGFALTVAIGIGTTLFTTLTFTR 424
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 115-592 4.73e-54

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 198.93  E-value: 4.73e-54
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  115 IDLLAGefsRQgIRLSryFYDVRD---TDEEVIAKLRDEaeealsrareiIRNRVDQYGVAEPQIQVQGaRRIIVALPG- 190
Cdd:PRK12911   582 IDFVGG---KQ-IRLA--FKDHQGkqlTDKEGILKVSDE-----------LYARLNKLGVSEVEMRREG-DHIHLSVPGs 643

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  191 --VSDQErirklLRGTAKLEFKLVRD----REAMLAGLERINAALEEDVESGSEAGEDTVDVPANPLFEHmtvmENGRVy 264
Cdd:PRK12911   644 agISSAE-----ILGTSKMSFHVVNEqfssYSALRYEVQRFLDYLWFTARSQDKTSPEAINRLASALFNG----DEGSA- 713

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  265 vPQYSRDYLLSLfQRDDIArlLPK----------DTEFRMSArtIEGQDGTQFHDLYLLKKTPELTGNVITEAKATFGAS 334
Cdd:PRK12911   714 -PASVREAVTKL-KEEGLA--FSKsgleggsaslDTTYSMIA--IEKDSEEKANPLMIVFRNYALDGASLKNIRPEFAVG 787

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  335 -------AMQPEVTMKMNAEG---------TSKWAR--ITG-------ANIGRQIAIVLDGAVYSAPVVESKIPGGSSVi 389
Cdd:PRK12911   788 egyvlnfSVKDTATFSDARELsptesfhawTSAYCQegVSGtkngqfsGGRGWRMAVVLDGYVVSDPVLNVPLKDHASV- 866

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  390 NGIESLEEAQDLEIVLKAGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYRKAGISADLALVLNIL 469
Cdd:PRK12911   867 SGKFSHREVHRLATDLKSGAMSFVPEVLSEEVISPELGKSQRTQGIISVCLGLAVLIVLMSVYYRFGGVIASGAVLLNLL 946

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  470 FVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDSQITTLGAGFLLYV 549
Cdd:PRK12911   947 LIWAALQYLDAPLTLSGLAGIVLAMGMAVDANVLVFERIREEYLLSRSLSESVEAGYKKAFSAIFDSNLTTILASALLLM 1026

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 1859508042  550 YGIGPIQGFAVTLMIGTAASLFTALVVTKAIFDLLISKNLLTE 592
Cdd:PRK12911  1027 LDTGPIKGFALTLIIGIFSSMFTALFMTKFFFMIWMNKTQETQ 1069
2A0604s01 TIGR00916
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ...
 420-574 1.26e-49

protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273336 [Multi-domain]  Cd Length: 192  Bit Score: 170.52  E-value: 1.26e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 420 RTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYRKAGISADLALVLN-ILFVLSVLAGFGAALTLPGIAGLVLTIGMAV 498
Cdd:TIGR00916  35 GTVGPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHdVILILGVLSLFGATLTLPGIAGLLTIIGYSV 114

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1859508042 499 DANVLIFERIREEI--GQKKNLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTAL 574
Cdd:TIGR00916 115 DDTVVIFDRIREELrkYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
secD PRK08343
preprotein translocase subunit SecD; Reviewed
 319-565 5.31e-24

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 236245 [Multi-domain]  Cd Length: 417  Bit Score: 104.57  E-value: 5.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 319 LTGNVITE-AKATFGASAMQPEVTMKMNAEGTSKWARI------TGANIGRQIAIVLDG-AVYSAPVVE---SKIPGGSS 387
Cdd:PRK08343  131 LTGDDIESvGSPSQDPSGGAWGVPFTLSEDGAEKFAEVakgkgaTDDPSGHPLDMYLDGeLIYAAPLSPdlaSGLASGPV 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 388 VIN------GIESLEEAQDLEIVLKAGALPAPVRIIEERTVGPSLGSDYIRSGLLsAGWGLFIVAVFMIFY-YRKAGISA 460
Cdd:PRK08343  211 VITvgstgtTEEAKEEAKELYIHLRSGALPVKLDIEGSGSVSPSLGEQFKKGSLI-AGLLALLAVALVVFLrYREPRIAL 289

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 461 DLAL--VLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKnlRTAVETGYSKAFSAIIDSQI 538
Cdd:PRK08343  290 PMVItsLSEVIIILGFAALIGWQLDLASIAGIIAVIGTGVDDLIIITDEVLHEGKVPS--RKVFLSRIKRAFFIIFAAAA 367

                         250       260
                  ....*....|....*....|....*..
gi 1859508042 539 TTLGAGFLLYVYGIGPIQGFAVTLMIG 565
Cdd:PRK08343  368 TTIAAMSPLAVMGLGDLKGFAITTILG 394
SecD_SecF pfam02355
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ...
 416-580 5.72e-18

Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.


Pssm-ID: 280510 [Multi-domain]  Cd Length: 189  Bit Score: 82.27  E-value: 5.72e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 416 IIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYR-KAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTI 494
Cdd:pfam02355  15 IISIETVGPTVGSELARKAVLALLFALLLILIYVGLRFEwRFALGAIIALAHDVIITVGVFSLFGIEVDLATVAALLTII 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 495 GMAVDANVLIFERIREEIGQKK--NLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFT 572
Cdd:pfam02355  95 GYSVNDTVVVFDRVRENLRKKTraTLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALLVGVIVGTYS 174


                  ....*...
gi 1859508042 573 ALVVTKAI 580
Cdd:pfam02355 175 SIFIASPI 182
3a0501s07 TIGR00966
protein-export membrane protein SecF; This bacterial protein is always found with the ...
 414-573 9.58e-17

protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273368 [Multi-domain]  Cd Length: 246  Bit Score: 80.01  E-value: 9.58e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 414 VRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYY-RKAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVL 492
Cdd:TIGR00966  80 AEIRSIDAVGPSVGGELARKAVLALLAALVLILIYITVRFeWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALLT 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 493 TIGMAVDANVLIFERIREEIGQKK--NLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMI----GT 566
Cdd:TIGR00966 160 IIGYSINDTVVVFDRIRENLRKYTrkTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVgvivGT 239


                  ....*..
gi 1859508042 567 AASLFTA 573
Cdd:TIGR00966 240 YSSIFIA 246
SecF COG0341
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ...
 393-573 2.07e-15

Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440110 [Multi-domain]  Cd Length: 291  Bit Score: 77.01  E-value: 2.07e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 393 ESLEEAQDLEIVLKAGAlpAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYR-KAGISADLALVLNILFV 471
Cdd:COG0341    96 ESAEEVEKVRAALKEAF--GDVEIVRVEFVGPTVGKELTRKALLALLVALIGILIYIAFRFEwRFAVGAVVALLHDVLIT 173

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 472 LSVLAGFGAALTLPGIAGLvLTI-GMAVDANVLIFERIREeigqkkNLRtavetGYSKA-FSAIIDSQI----------- 538
Cdd:COG0341   174 LGIFSLFGLEFDLTFIAAL-LTIiGYSLNDTVVVFDRIRE------NLR-----KYRKMtLAEIINLSInqtlsrtints 241

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1859508042 539 -TTLGAGFLLYVYGIGPIQGFAVTLMIG----TAASLFTA 573
Cdd:COG0341   242 lTTLLVVLALLFFGGETLRDFALALLIGiivgTYSSIFIA 281
MMPL COG1033
Predicted exporter protein, RND superfamily [General function prediction only];
431-576 9.56e-14

Predicted exporter protein, RND superfamily [General function prediction only];


Pssm-ID: 440656 [Multi-domain]  Cd Length: 767  Bit Score: 74.51  E-value: 9.56e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 431 IRSGLLSAGWGLFIVAVFMIFYYR--KAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERI 508
Cdd:COG1033   604 IESQIRSLLLALLLIFLLLLLAFRslRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRY 683

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1859508042 509 REEIGQKKNLRTAVETGYSKAFSAIIDSQITTLgAGFLLYVY-GIGPIQGFAVTLMIGTAASLFTALVV 576
Cdd:COG1033   684 REERRKGGDLEEAIRRALRTTGKAILFTSLTLA-AGFGVLLFsSFPPLADFGLLLALGLLVALLAALLL 751
RND_1 NF037998
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ...
 442-593 2.23e-13

protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.


Pssm-ID: 468306  Cd Length: 1237  Bit Score: 73.66  E-value: 2.23e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  442 LFIVA----VFMIFYYRKAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKK- 516
Cdd:NF037998   451 LLILAiaimIYLLFAYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYKNKr 530

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1859508042  517 NLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAIFDLLISKNLLTER 593
Cdd:NF037998   531 SIEESFKIANKETIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVARLMIWLTIKLQWFKKY 607
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 389-573 5.22e-13

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 72.19  E-value: 5.22e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 389 INGIESLEEAQDLEIVLK-----AGALPAPVRIIEerTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYR-KAGISADL 462
Cdd:PRK13024  531 TYGILSDDEEADTEIVAKlknalKNDKGGTIPSSE--TVGPTVGKELARNAIIAVLIALIGILLYILIRFEwTFSLGAIL 608

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 463 ALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQ--KKNLRTAVETGYSKAFSAIIDSQITT 540
Cdd:PRK13024  609 ALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIRENLRLykKKDLREIVNKSINQTLSRTINTSLTT 688

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1859508042 541 LGAGFLLYVYGIGPIQGFAVTLMIG----TAASLFTA 573
Cdd:PRK13024  689 LLVLLALLIFGGSSLRNFSLALLVGlivgTYSSIFIA 725
MMPL COG1033
Predicted exporter protein, RND superfamily [General function prediction only];
439-587 1.57e-11

Predicted exporter protein, RND superfamily [General function prediction only];


Pssm-ID: 440656 [Multi-domain]  Cd Length: 767  Bit Score: 67.19  E-value: 1.57e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 439 GWGLFIVAVFMIFYYR--KAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKK 516
Cdd:COG1033   225 PLALLLILLLLFLFFRslRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGL 304

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1859508042 517 NLRTAVETGYSKAFSAIIDSQITTlGAGFL-LYVYGIGPIQGFAVTLMIGTAASLFTALVVT---KAIFDLLISK 587
Cdd:COG1033   305 DKREALREALRKLGPPVLLTSLTT-AIGFLsLLFSDIPPIRDFGIVAAIGVLLAFLTSLTLLpalLSLLPRPKPK 378
MMPL pfam03176
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ...
 441-580 1.76e-08

MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.


Pssm-ID: 308676 [Multi-domain]  Cd Length: 332  Bit Score: 56.53  E-value: 1.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 441 GLFIVAVFMIFYYRkagiSADLALVLNILFVLSVLAGFGAALTLPGIAGL-----------VLTIGMAVDANVLIFERIR 509
Cdd:pfam03176 151 TLVVIFIILLIVYR----SVVAALLPLLTVGLSLGAAQGLVAILAHILGIglstfalnllvVLLIAVGTDYALFLVSRYR 226

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1859508042 510 EEIGQKKNLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAI 580
Cdd:pfam03176 227 EELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLAALTLLPAL 297
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
 398-580 4.76e-08

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 56.00  E-value: 4.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 398 AQDLEIVLKAGALPAPVRIieERTVGPSLGSDYIRS-----GLLSAGWGLFIVAVFMIFYYR-KAGISADLALVLNILFV 471
Cdd:TIGR00921 157 YNDVERSLERTNPPSGKFL--DVTGSPAINYDIEREfgkdmGTTMAISGILVVLVLLLDFKRwWRPLLPLVIILFGVAWV 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 472 LSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDSQITTLgAGFL-LYVY 550
Cdd:TIGR00921 235 LGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTS-AGFAaLALS 313

                         170       180       190
                  ....*....|....*....|....*....|
gi 1859508042 551 GIGPIQGFAVTLMIGTAASLFTALVVTKAI 580
Cdd:TIGR00921 314 EFPMVSEFGLGLVAGLITAYLLTLLVLPAL 343
YdfJ COG2409
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ...
 432-584 1.44e-07

Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];


Pssm-ID: 441964 [Multi-domain]  Cd Length: 697  Bit Score: 54.39  E-value: 1.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 432 RSGLLSAGWGLFIVAVFMIFYYRkagiSADLALVLNILFVLSVLAGFGAALTL----------PGIAgLVLTIGMAVDAN 501
Cdd:COG2409   169 EDLGRAELITLPVALVVLLLVFR----SLVAALLPLLTAGLAVGVALGLLALLaaftdvssfaPNLL-TMLGLGVGIDYA 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 502 VLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAIF 581
Cdd:COG2409   244 LFLVSRYREELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLAALTLLPALL 323


                  ...
gi 1859508042 582 DLL 584
Cdd:COG2409   324 ALL 326
secF PRK13021
preprotein translocase subunit SecF; Reviewed
 414-584 3.13e-07

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 237274 [Multi-domain]  Cd Length: 297  Bit Score: 52.55  E-value: 3.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 414 VRIIEERTVGPSLGSDYIRSGLLSagwglFIVAVFMI-------FYYRKAgISADLALVLNILFVLSVLAGFGAALTLPG 486
Cdd:PRK13021  108 VQVLNSSIVGPQVGQELAEQGGLA-----LLVAMLCIlgylsyrFEWRLA-SGALFALVHDVIFVLAFFALTQMEFNLTV 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 487 IAGLVLTIGMAVDANVLIFERIREEIGQKK--NLRTAVETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMI 564
Cdd:PRK13021  182 LAAVLAILGYSLNDSIIIADRIRELLIAKPklAIQEINNQAIVATFSRTMVTSGTTLMTVGALWIMGGGPLEGFSIAMFI 261

                         170       180
                  ....*....|....*....|
gi 1859508042 565 GTAASLFTALVVTKAIFDLL 584
Cdd:PRK13021  262 GILTGTFSSISVGTSLPELL 281
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
 438-583 4.54e-07

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 52.92  E-value: 4.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 438 AGWGLFIVAVFMIFYYRKAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKN 517
Cdd:TIGR00921 575 AGAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSIHLAERYFEERKEHGP 654

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1859508042 518 lRTAVETGYSKAFSAIIDSQITTLGaGFL-LYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAIFDL 583
Cdd:TIGR00921 655 -KEAITHTMERTGPGILFSGLTTAG-GFLsLLLSHFPIMRNFGLVQGIGVLSSLTAALVVFPALLVL 719
PRK13023 PRK13023
protein translocase subunit SecDF;
374-581 1.96e-06

protein translocase subunit SecDF;


Pssm-ID: 171842 [Multi-domain]  Cd Length: 758  Bit Score: 50.77  E-value: 1.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 374 SAPVVESKIPGGSSVINGIESLEEAQDLEIVLK-AGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFY 452
Cdd:PRK13023  519 SARVLPAKSPRSALVIIGSQEVGDDAEQTVAVKlRGEFEQDYSFQRVDVVGPTVSEQLSRAGVLAVILSLIGIFIYVWFR 598

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 453 YR-KAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKN--LRTAVETGYSKA 529
Cdd:PRK13023  599 FRwQLALGAVLSTLHDVVILSGMFIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDRVRENLRRYKSapLPAIIDASINQT 678

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1859508042 530 FSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAIF 581
Cdd:PRK13023  679 LSRTLLTSFVTFLAHVPLYAFGGSEIRMFALALSVGIIVASYSSIFIAAPLL 730
PRK08578 PRK08578
preprotein translocase subunit SecF; Reviewed
 419-549 2.92e-06

preprotein translocase subunit SecF; Reviewed


Pssm-ID: 236302 [Multi-domain]  Cd Length: 292  Bit Score: 49.16  E-value: 2.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 419 ERTVGPSLGSDYIRSGLLSAGWGLFIVAVFMIFYYRKAGISAD--LALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGM 496
Cdd:PRK08578  121 EKQIGPTFGSQFQEQALKAVGFAFIGMAVVVFLIFRTPVPSLAviLSAFSDIIIALALMNLFGIELSLATVAALLMLIGY 200

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1859508042 497 AVDANVLIFERIREEigqkknlRTAVETGYSKAFSAIIDSQITTLGAGFLLYV 549
Cdd:PRK08578  201 SVDSDILLTTRVLKR-------RGTFDESIKRAMRTGITMTLTTIAAMAVLYI 246
PRK14726 PRK14726
protein translocase subunit SecDF;
393-573 3.47e-05

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 47.02  E-value: 3.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 393 ESLEEAQDLEIVLKAGALPAPVRIIEERTVGPSLGSDYIRSGLLSAGWGLFIVAVFM-IFYYRKAGISADLALVLNILFV 471
Cdd:PRK14726  633 DGGENAEQSAVTLVRGELEDDYDFRRVEVVGPAVSGELTMAATLGVLAALAAILIYIwIRFEWQFAVGAIIATLHDVILT 712

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 472 LSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKN--LRTAVETGYSKAFSAIIDSQITTLGAGFLLYV 549
Cdd:PRK14726  713 LGLFVLTGIEFNLTSIAAILTIVGYSLNDTVVVYDRVRENLRRYKKmpLPILIDASINQTLSRTVLTSATTLLALLALYL 792

                         170       180
                  ....*....|....*....|....*...
gi 1859508042 550 YGIGPIQGFAVTLM----IGTAASLFTA 573
Cdd:PRK14726  793 FGGEVIRSFTFAMLfgvaVGTFSSIYIA 820
ACR_tran pfam00873
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
 444-586 1.34e-04

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


Pssm-ID: 395701 [Multi-domain]  Cd Length: 1021  Bit Score: 44.98  E-value: 1.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  444 IVAVFMIFY-----YRKAGISAdLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANVLIFERIREEIG--QKK 516
Cdd:pfam00873  341 IVLVILVMFlflqnWRATLIPA-IAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDDAIVVVENIERVLEenGLK 419

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1859508042  517 NLRTAVEtGYSKAFSAIIDSQItTLGAGFL--LYVYGI-GPI-QGFAVTLMIGTAASLFTALVVTKAIFDLLIS 586
Cdd:pfam00873  420 PLEAAYK-SMGEIGGALVAIAL-VLSAVFLpiLFLGGLtGRIfRQFAITIVLAILLSVLVALTLTPALCATLLK 491
COG4258 COG4258
Predicted exporter [General function prediction only];
431-576 1.89e-04

Predicted exporter [General function prediction only];


Pssm-ID: 443400 [Multi-domain]  Cd Length: 783  Bit Score: 44.46  E-value: 1.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 431 IRSGLLSAGWGLFIVAVFMIFYYR-KAGISADLALVLNILFVLSVLAGFGAALTLPGIAGLVLTIGMAVDANvlIFerIR 509
Cdd:COG4258   639 NDALWLLLLALLLILLLLLLRLRSlRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYA--LF--FT 714

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1859508042 510 EEIGQKKNLRTavetgyskAFSAIIDSQITTLgAGF-LLYVYGIGPIQGFAVTLMIGTAASLFTALVV 576
Cdd:COG4258   715 EGLLDKGELAR--------TLLSILLAALTTL-LGFgLLAFSSTPALRSFGLTVLLGILLALLLAPLL 773
actII TIGR00833
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ...
 463-587 1.19e-03

Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 129913 [Multi-domain]  Cd Length: 910  Bit Score: 41.88  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 463 ALVLNILFVLSVLAGFGAALTLPGIAG----------------LVLTIGMAVDANVLIFERIREEIgqKKNLRTAVETGY 526
Cdd:TIGR00833 767 APVAPIVLIGSVALSYLWALGLSVLAFqhilgaelhwsvlagvFVLLVALGVDYNMLLVSRIKEES--PAGNRTGIIRAL 844

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1859508042 527 SKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFAVTLMIGTAASLFTALVVTKAIFDLLISK 587
Cdd:TIGR00833 845 GSTGGVITAAGLVFAGTMAALASAQLTAIAQFGFTVGVGILLDTFIVRSVTVPALTLLLGR 905
PRK12911 PRK12911
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
 441-573 2.38e-03

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 171815 [Multi-domain]  Cd Length: 1403  Bit Score: 41.00  E-value: 2.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  441 GLFIVAVFMIFYYRKAgISADLALVLNILFVLSVLAGFGAALT-----LPGIAGLVLTIGMAVDANVLIFERIREEigQK 515
Cdd:PRK12911  1245 GIILLYVSLRFEWRYA-FSAICALIHDLLATCAVLVALHFFLQkiqidLQAIGALMTVLGYSLNNTLIIFDRIRED--RQ 1321

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1859508042  516 KNLRTA----VETGYSKAFSAIIDSQITTLGAGFLLYVYGIGPIQGFA----VTLMIGTAASLFTA 573
Cdd:PRK12911  1322 EKLFTPmpilINDALQKTLGRTVMTTATTLSVLLILLFVGGGSIFNFAfimtIGILLGTLSSLYIA 1387
AcrB COG0841
Multidrug efflux pump subunit AcrB [Defense mechanisms];
394-584 2.43e-03

Multidrug efflux pump subunit AcrB [Defense mechanisms];


Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 40.86  E-value: 2.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  394 SLEEA-QDLEIVLKAGALPAPVRII------EERTVGPSLGSdyirsgllsagwgLFIVAVFMIFyyrkagisadlaLVL 466
Cdd:COG0841    814 SLGEAlAAIEELAAELKLPPGVSIEftgqaeEEQESFSSLGL-------------AFLLALLLVY------------LVL 868

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  467 NILF--------VLSV--LAGFGA---------ALTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVETGYS 527
Cdd:COG0841    869 AAQFesfiqpliILLTvpLALIGAllgllltgtPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEAAR 948

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1859508042  528 KAFSAIIdsqITTL--GAGFLLYVYGIGP----IQGFAVTLMIGTAASLFTALVVTKAIFDLL 584
Cdd:COG0841    949 LRLRPIL---MTSLatILGLLPLALGTGAgaefRQPLGIAVIGGLLFSTLLTLFVVPVLYVLL 1008
HpnN TIGR03480
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ...
 385-584 2.64e-03

hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.


Pssm-ID: 274598 [Multi-domain]  Cd Length: 862  Bit Score: 40.75  E-value: 2.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 385 GSSVINGIESleEAQDLEIVLKAGA---LPAPVRIIEERTVGPSLGSDYirSGLLSagwgLFIVAVFMIFYYRKAGIsad 461
Cdd:TIGR03480 227 AEKAINAIRA--AAKDLRLDEDHGVtvrLTGEVALSDEELATVSEGATV--AGLLS----FVLVLVLLWLALRSPRL--- 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 462 LALVLNILFV-LSVLAGFGAA----LTLPGIAGLVLTIGMAVDANVLIFERIREEIGQKKNLRTAVETGYSKAFSAIIDS 536
Cdd:TIGR03480 296 VFAVLVTLIVgLILTAAFATLavghLNLISVAFAVLFIGLGVDFAIQFSLRYREERFRGGNHREALSVAARRMGAALLLA 375

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1859508042 537 QITTlGAGFLLYVY----GI---GPIQGFavtlmiGTAASLFTALVVTKAIFDLL 584
Cdd:TIGR03480 376 ALAT-AAGFFAFLPtdykGVselGIIAGT------GMFIALFVTLTVLPALLRLL 423
AcrB COG0841
Multidrug efflux pump subunit AcrB [Defense mechanisms];
472-577 5.37e-03

Multidrug efflux pump subunit AcrB [Defense mechanisms];


Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 39.70  E-value: 5.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042  472 LSVLAGFGAA---------LTLpgiAGLVLTIGMAVDA------NVlifERIREEigqKKNLRTAVETGYSKAFSAIIDS 536
Cdd:COG0841    367 VSLIGTFAVMyllgfslniLTL---FALVLAIGIVVDDaivvveNI---ERHMEE---GLSPLEAAIKGAREVAGAVIAS 437

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1859508042  537 QITTLgAGF--LLYVYGI-GPI-QGFAVTLMIGTAASLFTALVVT 577
Cdd:COG0841    438 TLTLV-AVFlpLAFMGGItGQLfRQFALTVAIALLISLFVALTLT 481
YdfJ COG2409
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ...
 462-576 6.11e-03

Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];


Pssm-ID: 441964 [Multi-domain]  Cd Length: 697  Bit Score: 39.75  E-value: 6.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 462 LALVLNILFVLSVLAGFGAA------------LTLPGIAGLVLTIGMAV------DANVLIFERIREEIGQKKNLRTAVE 523
Cdd:COG2409   543 APLKAVLTNLLSLGAALGVLvlvfqhgwlllgFTPGPLDSFVPLLLFVIlfglgmDYEVFLVSRIREEYDRGGGTREAVI 622

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1859508042 524 TGYSKafSAIIdsqITTLG-------AGFLlyVYGIGPIQGFAVTLMIGTaasLFTALVV 576
Cdd:COG2409   623 RGLAR--TGRV---ITSAAlimaavfAAFA--TSPLVFLKQIGFGLAVGV---LLDAFVV 672
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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