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Conserved domains on  [gi|1850342|gb|AAB48030|]
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Tpr [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR_MLP1_2 pfam07926
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of ...
 1040-1166 2.40e-26

TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of human TPR protein and to yeast myosin-like proteins 1 (MLP1) and 2 (MLP2). These proteins share a number of features; for example, they all have coiled-coil regions and all three are associated with nuclear pores. TPR is thought to be a component of nuclear pore complex- attached intra-nuclear filaments, and is implicated in nuclear protein import. Moreover, its N-terminal region is involved in the activation of oncogenic kinases, possibly by mediating the dimerization of kinase domains or by targeting these kinases to the nuclear pore complex. MLP1 and MLP2 are involved in the process of telomere length regulation, where they are thought to interact with proteins such as Tel1p and modulate their activity.


:

Pssm-ID: 462316 [Multi-domain]  Cd Length: 129  Bit Score: 106.18  E-value: 2.40e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1040 LSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQK 1119
Cdd:pfam07926    3 LSSLQSEIKRLKEEAADAEAQLQKLQEDLEKQAEIAREAQQNYERELVLHAEDIKALQALREELNELKAEIAELKAEAES 82

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1850342    1120 AESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKL 1166
Cdd:pfam07926   83 AKAELEESEESWEEQKKELEKELSELEKRIEDLNEQNKLLHDQLESL 129
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 773-1619 2.68e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.52  E-value: 2.68e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     773 KLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRL---SSQIEKLEHEIS 849
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyalANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     850 HLKKKLENEVEQRhtltRNLDVQLLDTKRQLD-TETNLHLNTKEL------LKNAQKEIATLKRHLSNMEVQVASQSSQR 922
Cdd:TIGR02168  306 ILRERLANLERQL----EELEAQLEELESKLDeLAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     923 TGKgqpsnKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLnkEKQVTEEVRKNIEVRLKESAEFQT 1002
Cdd:TIGR02168  382 ETL-----RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL--EEAELKELQAELEELEEELEELQE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1003 QLEKKLMEVEKEKQELqDDKRRAIESMEQQLSELKKTLSSVQNEVQEA--LQRASTALSNEQQARRDCQEQAKIAVEAQN 1080
Cdd:TIGR02168  455 ELERLEEALEELREEL-EEAEQALDAAERELAQLQARLDSLERLQENLegFSEGVKALLKNQSGLSGILGVLSELISVDE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1081 KYEREL------MLHAADVEALQAAKEQVS---KMASVRQHLEETTQKAESQLleckaswEERERMLKDEVSKCVCRCED 1151
Cdd:TIGR02168  534 GYEAAIeaalggRLQAVVVENLNAAKKAIAflkQNELGRVTFLPLDSIKGTEI-------QGNDREILKNIEGFLGVAKD 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1152 LEKQNRLLHDQIEKLSDKVVasVKEGVQGPLNVslseegksQEQILEILRFIRREKEIAETRFEVAqveslryrqrvell 1231
Cdd:TIGR02168  607 LVKFDPKLRKALSYLLGGVL--VVDDLDNALEL--------AKKLRPGYRIVTLDGDLVRPGGVIT-------------- 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1232 erelqelqdslnaeREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDIlplqean 1311
Cdd:TIGR02168  663 --------------GGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEL------- 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1312 AELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDtEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTN 1391
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE-AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1392 N-------QNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKvmetsaqssg 1464
Cdd:TIGR02168  801 LrealdelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE---------- 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1465 dHQEQHVSVQ-EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQD---LQDRTTQEE 1540
Cdd:TIGR02168  871 -LESELEALLnERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRidnLQERLSEEY 949

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1541 QLRQQ--------ITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELdvriTALKSQYEGRISR 1612
Cdd:TIGR02168  950 SLTLEeaealenkIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDL----TEAKETLEEAIEE 1025


                   ....*..
gi 1850342    1613 LERELRE 1619
Cdd:TIGR02168 1026 IDREARE 1032
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 227-1066 3.01e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 3.01e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     227 ENKKEEVSRLEEqmnglktSNEHLQKhVEDLLTKLKEAK---EQQASMEEKFHnELNAHIK------LSNLYKSAADDSE 297
Cdd:TIGR02168  172 ERRKETERKLER-------TRENLDR-LEDILNELERQLkslERQAEKAERYK-ELKAELRelelalLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     298 AKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEqskdqmekEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAA 377
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVS--------ELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     378 MSPTAAAVAKIVKPGMKLTELynayvetqdQLLLEKLENKrinkyLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVK 457
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDEL---------AEELAELEEK-----LEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     458 LEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADissssevisqhl 537
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE------------ 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     538 vsyrnIEELQQQNQRLLVALRELgetreREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSiVRQRDMYRIL 617
Cdd:TIGR02168  449 -----LEELQEELERLEEALEEL-----REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG-VKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     618 LSQTTGVAIPLH--------------ASSLDDV---------SLASTPKRPSTSQTvsTPAPVPVIESTEAIEAKAALKQ 674
Cdd:TIGR02168  518 LSGILGVLSELIsvdegyeaaieaalGGRLQAVvvenlnaakKAIAFLKQNELGRV--TFLPLDSIKGTEIQGNDREILK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     675 LQEIFENYKKEKAE-NEKIQN------------EQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQdnveGYRREITS 741
Cdd:TIGR02168  596 NIEGFLGVAKDLVKfDPKLRKalsyllggvlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITG----GSAKTNSS 671

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     742 LHERNQKLTATTQKQEQiintMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEqrgqnllltnlqt 821
Cdd:TIGR02168  672 ILERRREIEELEEKIEE----LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD------------- 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     822 iqgilersetetKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLhlntKELLKNAQKEI 901
Cdd:TIGR02168  735 ------------LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL----EAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     902 ATLKRHLS--NMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN-- 977
Cdd:TIGR02168  799 KALREALDelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEal 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     978 -KEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD---DKRRAIESMEQQLSELKKTLSSVQN-EVQEALQ 1052
Cdd:TIGR02168  879 lNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDNLQERLSEEYSlTLEEAEA 958

                          890
                   ....*....|....
gi 1850342    1053 RASTALSNEQQARR 1066
Cdd:TIGR02168  959 LENKIEDDEEEARR 972
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 53-354 3.38e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 3.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      53 QYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLK-ALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLirtn 131
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSqELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL---- 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     132 ERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEK-ELLHSQNTWLNTELKTKTDELLA 210
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     211 LgrekgNEILELKcnLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKfHNELNAHIKLSNLYK 290
Cdd:TIGR02169  827 E-----KEYLEKE--IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR-LGDLKKERDELEAQL 898

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1850342     291 SAAddsEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEK--IGRLEKELE 354
Cdd:TIGR02169  899 REL---ERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsLEDVQAELQ 961
DUF5585 super family cl39316
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 1640-1877 2.13e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


The actual alignment was detected with superfamily member pfam17823:

Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 43.02  E-value: 2.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1640 EQQRQITLKTTPASGErgiaSTSDPPTANIKPTPVVSTPSKV---TAAAMAG----NKSTPRASIRPMVTPATVTNPTTT 1712
Cdd:pfam17823   89 EHTPHGTDLSEPATRE----GAADGAASRALAAAASSSPSSAaqsLPAAIAAlpseAFSAPRAAACRANASAAPRAAIAA 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1713 PTA----TVMPTTQVESQEAMQSEGPVEHVPVFGSTS---------GSVRSTSPNVQPSISQ-----PILTVQQQTQATA 1774
Cdd:pfam17823  165 ASAphaaSPAPRTAASSTTAASSTTAASSAPTTAASSapatltparGISTAATATGHPAAGTalaavGNSSPAAGTVTAA 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1775 FVQPTQQSHPQIEPANQELSSNIVEVVQSSPVER---PSTSTAVfGTVSATPSSSLpkrtREEEEDSTIEAS-DQVSDDT 1850
Cdd:pfam17823  245 VGTVTPAALATLAAAAGTVASAAGTINMGDPHARrlsPAKHMPS-DTMARNPAAPM----GAQAQGPIIQVStDQPVHNT 319

                          250       260
                   ....*....|....*....|....*..
gi 1850342    1851 VEMPLPKKLKSVTPVGTEEEVMAEEST 1877
Cdd:pfam17823  320 AGEPTPSPSNTTLEPNTPKSVASTNLA 346
 
Name Accession Description Interval E-value
TPR_MLP1_2 pfam07926
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of ...
 1040-1166 2.40e-26

TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of human TPR protein and to yeast myosin-like proteins 1 (MLP1) and 2 (MLP2). These proteins share a number of features; for example, they all have coiled-coil regions and all three are associated with nuclear pores. TPR is thought to be a component of nuclear pore complex- attached intra-nuclear filaments, and is implicated in nuclear protein import. Moreover, its N-terminal region is involved in the activation of oncogenic kinases, possibly by mediating the dimerization of kinase domains or by targeting these kinases to the nuclear pore complex. MLP1 and MLP2 are involved in the process of telomere length regulation, where they are thought to interact with proteins such as Tel1p and modulate their activity.


Pssm-ID: 462316 [Multi-domain]  Cd Length: 129  Bit Score: 106.18  E-value: 2.40e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1040 LSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQK 1119
Cdd:pfam07926    3 LSSLQSEIKRLKEEAADAEAQLQKLQEDLEKQAEIAREAQQNYERELVLHAEDIKALQALREELNELKAEIAELKAEAES 82

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1850342    1120 AESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKL 1166
Cdd:pfam07926   83 AKAELEESEESWEEQKKELEKELSELEKRIEDLNEQNKLLHDQLESL 129
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 773-1619 2.68e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.52  E-value: 2.68e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     773 KLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRL---SSQIEKLEHEIS 849
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyalANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     850 HLKKKLENEVEQRhtltRNLDVQLLDTKRQLD-TETNLHLNTKEL------LKNAQKEIATLKRHLSNMEVQVASQSSQR 922
Cdd:TIGR02168  306 ILRERLANLERQL----EELEAQLEELESKLDeLAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     923 TGKgqpsnKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLnkEKQVTEEVRKNIEVRLKESAEFQT 1002
Cdd:TIGR02168  382 ETL-----RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL--EEAELKELQAELEELEEELEELQE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1003 QLEKKLMEVEKEKQELqDDKRRAIESMEQQLSELKKTLSSVQNEVQEA--LQRASTALSNEQQARRDCQEQAKIAVEAQN 1080
Cdd:TIGR02168  455 ELERLEEALEELREEL-EEAEQALDAAERELAQLQARLDSLERLQENLegFSEGVKALLKNQSGLSGILGVLSELISVDE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1081 KYEREL------MLHAADVEALQAAKEQVS---KMASVRQHLEETTQKAESQLleckaswEERERMLKDEVSKCVCRCED 1151
Cdd:TIGR02168  534 GYEAAIeaalggRLQAVVVENLNAAKKAIAflkQNELGRVTFLPLDSIKGTEI-------QGNDREILKNIEGFLGVAKD 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1152 LEKQNRLLHDQIEKLSDKVVasVKEGVQGPLNVslseegksQEQILEILRFIRREKEIAETRFEVAqveslryrqrvell 1231
Cdd:TIGR02168  607 LVKFDPKLRKALSYLLGGVL--VVDDLDNALEL--------AKKLRPGYRIVTLDGDLVRPGGVIT-------------- 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1232 erelqelqdslnaeREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDIlplqean 1311
Cdd:TIGR02168  663 --------------GGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEL------- 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1312 AELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDtEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTN 1391
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE-AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1392 N-------QNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKvmetsaqssg 1464
Cdd:TIGR02168  801 LrealdelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE---------- 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1465 dHQEQHVSVQ-EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQD---LQDRTTQEE 1540
Cdd:TIGR02168  871 -LESELEALLnERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRidnLQERLSEEY 949

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1541 QLRQQ--------ITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELdvriTALKSQYEGRISR 1612
Cdd:TIGR02168  950 SLTLEeaealenkIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDL----TEAKETLEEAIEE 1025


                   ....*..
gi 1850342    1613 LERELRE 1619
Cdd:TIGR02168 1026 IDREARE 1032
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 227-1066 3.01e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 3.01e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     227 ENKKEEVSRLEEqmnglktSNEHLQKhVEDLLTKLKEAK---EQQASMEEKFHnELNAHIK------LSNLYKSAADDSE 297
Cdd:TIGR02168  172 ERRKETERKLER-------TRENLDR-LEDILNELERQLkslERQAEKAERYK-ELKAELRelelalLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     298 AKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEqskdqmekEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAA 377
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVS--------ELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     378 MSPTAAAVAKIVKPGMKLTELynayvetqdQLLLEKLENKrinkyLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVK 457
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDEL---------AEELAELEEK-----LEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     458 LEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADissssevisqhl 537
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE------------ 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     538 vsyrnIEELQQQNQRLLVALRELgetreREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSiVRQRDMYRIL 617
Cdd:TIGR02168  449 -----LEELQEELERLEEALEEL-----REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG-VKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     618 LSQTTGVAIPLH--------------ASSLDDV---------SLASTPKRPSTSQTvsTPAPVPVIESTEAIEAKAALKQ 674
Cdd:TIGR02168  518 LSGILGVLSELIsvdegyeaaieaalGGRLQAVvvenlnaakKAIAFLKQNELGRV--TFLPLDSIKGTEIQGNDREILK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     675 LQEIFENYKKEKAE-NEKIQN------------EQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQdnveGYRREITS 741
Cdd:TIGR02168  596 NIEGFLGVAKDLVKfDPKLRKalsyllggvlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITG----GSAKTNSS 671

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     742 LHERNQKLTATTQKQEQiintMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEqrgqnllltnlqt 821
Cdd:TIGR02168  672 ILERRREIEELEEKIEE----LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD------------- 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     822 iqgilersetetKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLhlntKELLKNAQKEI 901
Cdd:TIGR02168  735 ------------LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL----EAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     902 ATLKRHLS--NMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN-- 977
Cdd:TIGR02168  799 KALREALDelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEal 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     978 -KEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD---DKRRAIESMEQQLSELKKTLSSVQN-EVQEALQ 1052
Cdd:TIGR02168  879 lNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDNLQERLSEEYSlTLEEAEA 958

                          890
                   ....*....|....
gi 1850342    1053 RASTALSNEQQARR 1066
Cdd:TIGR02168  959 LENKIEDDEEEARR 972
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 36-620 8.18e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 8.18e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    36 IDGLKGRHEKFKVESEQ--QYFEIEKRLshsqerlvnETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIA----I 109
Cdd:COG1196  195 LGELERQLEPLERQAEKaeRYRELKEEL---------KELEAELLLLKLRELEAELEELEAELEELEAELEELEAelaeL 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   110 QSQFTRTKEELEAEKRDLIRTNER---LSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQE 186
Cdd:COG1196  266 EAELEELRLELEELELELEEAQAEeyeLLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   187 KELLHSQNTWLNTELKTKTDELLALGREKGNEILElkcnLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKE 266
Cdd:COG1196  346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE----LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   267 QQASMEEkfhnelnahiklsnlyksAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKI 346
Cdd:COG1196  422 ELEELEE------------------ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   347 GRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRinkyldei 426
Cdd:COG1196  484 EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED-------- 555

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   427 vkEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLME 506
Cdd:COG1196  556 --DEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   507 leeaRGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESA 586
Cdd:COG1196  634 ----AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                        570       580       590
                 ....*....|....*....|....*....|....
gi 1850342   587 LTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQ 620
Cdd:COG1196  710 AEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1353-1659 8.46e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 8.46e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1353 EYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASltnnqnlIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTIT 1432
Cdd:COG1196  233 KLRELEAELEELEAELEELEAELEELEAELAELEAE-------LEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1433 QVKKIGRRYKTQYEELKAQQDkvmETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEAR 1512
Cdd:COG1196  306 RLEERRRELEERLEELEEELA---ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1513 NLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEktrkAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQK 1592
Cdd:COG1196  383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE----ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1850342  1593 DELDVRITALKSQYEGRISRLERELREHQErhLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIA 1659
Cdd:COG1196  459 EALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523
PTZ00121 PTZ00121
MAEBL; Provisional
 930-1644 4.62e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.56  E-value: 4.62e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    930 NKEDVDDLVSQLRQTEEQVNDLkERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEfQTQLEKKLM 1009
Cdd:PTZ00121 1048 IDEDIDGNHEGKAEAKAHVGQD-EGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARK-AEEAKKKAE 1125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1010 EVEK-EKQELQDDKRRAIESMEQQlselkktlssvQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELML 1088
Cdd:PTZ00121 1126 DARKaEEARKAEDARKAEEARKAE-----------DAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELR 1194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1089 HAADVEALQAAK--EQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKL 1166
Cdd:PTZ00121 1195 KAEDARKAEAARkaEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA 1274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1167 SDKVVAsvkEGVQGPLNVSLSEEGKSQEQIleilrfiRREKEIAETRFEVAQVESLRYRQRVELLERELQELQdslnAER 1246
Cdd:PTZ00121 1275 EEARKA---DELKKAEEKKKADEAKKAEEK-------KKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKK----AEE 1340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1247 EKVQVTAKTmAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLElDILPLQEANAELSEKSGMLQAEKK 1326
Cdd:PTZ00121 1341 AKKAAEAAK-AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD-EAKKKAEEDKKKADELKKAAAAKK 1418

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1327 LLEEDVKRWKARNQHLVSQQKdpdTEEYRKllsEKEVHTKRIQQLTEEIGRLKAEIARSnasltnnqnlIQSLKEDLNKV 1406
Cdd:PTZ00121 1419 KADEAKKKAEEKKKADEAKKK---AEEAKK---ADEAKKKAEEAKKAEEAKKKAEEAKK----------ADEAKKKAEEA 1482

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1407 RTEKETIQKDLDAKiiDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQA 1486
Cdd:PTZ00121 1483 KKADEAKKKAEEAK--KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKA 1560

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1487 ETKSKSLESQVENLQKTLSEKETE-ARNLQEQTVQLQSELSRLRQDL---QDRTTQEEQLRQQITEKEEKTRKAIVAAKS 1562
Cdd:PTZ00121 1561 EEKKKAEEAKKAEEDKNMALRKAEeAKKAEEARIEEVMKLYEEEKKMkaeEAKKAEEAKIKAEELKKAEEEKKKVEQLKK 1640

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1563 KIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQE-RHLEQRDEPQEPSNKVPEQ 1641
Cdd:PTZ00121 1641 KEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEaKKAEELKKKEAEEKKKAEE 1720


                  ...
gi 1850342   1642 QRQ 1644
Cdd:PTZ00121 1721 LKK 1723
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
26-612 2.22e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 72.79  E-value: 2.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     26 EKFLADQQSEIDGLKGRHEKFKVESEqqyfEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEiaqdr 105
Cdd:PRK03918  164 YKNLGEVIKEIKRRIERLEKFIKRTE----NIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE----- 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    106 niaiqsqftRTKEELEAEKRdlirtnerlsqELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQasdvsvkyrekrlEQ 185
Cdd:PRK03918  235 ---------ELKEEIEELEK-----------ELESLEGSKRKLEEKIRELEERIEELKKEIEELE-------------EK 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    186 EKELlhsqntwlnTELKTKTDELLALGREKgNEILELKCNLEnkkEEVSRLEEQMNGLktsnEHLQKHVEDLLTKLKEAK 265
Cdd:PRK03918  282 VKEL---------KELKEKAEEYIKLSEFY-EEYLDELREIE---KRLSRLEEEINGI----EERIKELEEKEERLEELK 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    266 EQQASMEEKFhNELNAHIKLSNLYKSAADDSEAKSNELT-RAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEmle 344
Cdd:PRK03918  345 KKLKELEKRL-EELEERHELYEEAKAKKEELERLKKRLTgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE--- 420

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    345 kigrlEKELENANDLLSATKRK----GAILSEEE-LAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRI 419
Cdd:PRK03918  421 -----IKELKKAIEELKKAKGKcpvcGRELTEEHrKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEL 495

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    420 NKYLD--EIVKEVEAK-----APILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEdtdkANKQSSVLERDNRRMEIQ 492
Cdd:PRK03918  496 IKLKElaEQLKELEEKlkkynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE----LKKKLAELEKKLDELEEE 571

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    493 VKDLSQQIRVL-----------LMELEEARGNHV-IRDEEVSSADISSSSEVISQHLV-SYRNIEELQQQNQRLLVALRE 559
Cdd:PRK03918  572 LAELLKELEELgfesveeleerLKELEPFYNEYLeLKDAEKELEREEKELKKLEEELDkAFEELAETEKRLEELRKELEE 651

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1850342    560 LGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRD 612
Cdd:PRK03918  652 LEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 872-1684 1.92e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 69.76  E-value: 1.92e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     872 QLLDTKRQLDTETNLHLNTKELLKNAqkeIATLKRHLSNMEVQVASQSSQRTGKGQpsNKEDVDDLVSQLRQTEEQVNDL 951
Cdd:pfam15921   86 QVKDLQRRLNESNELHEKQKFYLRQS---VIDLQTKLQEMQMERDAMADIRRRESQ--SQEDLRNQLQNTVHELEAAKCL 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     952 KE-RLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQT--------QLEKKLMEVEKEKQELQDdk 1022
Cdd:pfam15921  161 KEdMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTmhfrslgsAISKILRELDTEISYLKG-- 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1023 rrAIESMEQQLSELKktlSSVQNEVQEALQ----RASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLhaadveALQA 1098
Cdd:pfam15921  239 --RIFPVEDQLEALK---SESQNKIELLLQqhqdRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEI------IQEQ 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1099 AKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLK-------DEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVV 1171
Cdd:pfam15921  308 ARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlanSELTEARTERDQFSQESGNLDDQLQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1172 ASVKE-GVQGPLNVSLSEEGKSQEQILEILRfirreKEIAETRFEVAQVESL--RYRQRVELLERELQELQDSLNAEREK 1248
Cdd:pfam15921  388 KREKElSLEKEQNKRLWDRDTGNSITIDHLR-----RELDDRNMEVQRLEALlkAMKSECQGQMERQMAAIQGKNESLEK 462

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1249 VQ-VTAKTMAQHEELMKKTETMNvvmeTNKMLREEKERLEQDLQ-QMQAKVRKLEldilplqEANAELSEksgmLQAEKK 1326
Cdd:pfam15921  463 VSsLTAQLESTKEMLRKVVEELT----AKKMTLESSERTVSDLTaSLQEKERAIE-------ATNAEITK----LRSRVD 527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1327 LLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQ-----QLTEEIGRLKAEIARSNASLTNNQNLIQSLKE 1401
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQienmtQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ 607

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1402 DLNKVRTEKETIQKDLDAKIIDIQ-EKVKTITqvkkigrrykTQYEELKAQQDKVMETSaqssgdhqeqhvsvQEMQELK 1480
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLElEKVKLVN----------AGSERLRAVKDIKQERD--------------QLLNEVK 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1481 ETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQ-------LRQQITEKeekt 1553
Cdd:pfam15921  664 TSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHamkvamgMQKQITAK---- 739

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1554 RKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQ-------QKDELDVRITALKSQ---YEGRISRLERELREHQER 1623
Cdd:pfam15921  740 RGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQelstvatEKNKMAGELEVLRSQerrLKEKVANMEVALDKASLQ 819

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1850342    1624 HLEQRDEPQEPSNKVPEQQRQITLKTTPASGErGIASTSDPPTANIKPTPVVSTPSKVTAA 1684
Cdd:pfam15921  820 FAECQDIIQRQEQESVRLKLQHTLDVKELQGP-GYTSNSSMKPRLLQPASFTRTHSNVPSS 879
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 158-1049 5.32e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.46  E-value: 5.32e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     158 TKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLE 237
Cdd:pfam02463  150 MKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYL 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     238 EQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEA 317
Cdd:pfam02463  230 DYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     318 GEANKAIQDHLLEVEQSKDQMEKEMlEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVkpgmKLTE 397
Cdd:pfam02463  310 VDDEEKLKESEKEKKKAEKELKKEK-EEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK----LESE 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     398 LYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEakapILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANK 477
Cdd:pfam02463  385 RLSSAAKLKEEELELKSEEEKEAQLLLELARQLE----DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     478 QSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVAL 557
Cdd:pfam02463  461 LKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     558 RELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQrdmYRILLSQTTGVAIPLHASSLDDVS 637
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKS---IAVLEIDPILNLAQLDKATLEADE 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     638 LASTPKRPSTSQTVSTpapvpviESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQ 717
Cdd:pfam02463  618 DDKRAKVVEGILKDTE-------LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELA 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     718 LDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEiraENLKKEKEMLKLSEVR 797
Cdd:pfam02463  691 KEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEE---EEKSRLKKEEKEEEKS 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     798 LSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTK 877
Cdd:pfam02463  768 ELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     878 RQLDTETNLHLNTKELLKNAQKEIATLKRHLSN-MEVQVASQSSQRTGKGQpsnKEDVDDLVSQLRQTEEQVNDLKERLK 956
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLLKEEELEeQKLKDELESKEEKEKEE---KKELEEESQKLNLLEEKENEIEERIK 924

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     957 TSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQdDKRRAIESMEQQLSEL 1036
Cdd:pfam02463  925 EEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKE-ERYNKDELEKERLEEE 1003

                          890
                   ....*....|...
gi 1850342    1037 KKTLSSVQNEVQE 1049
Cdd:pfam02463 1004 KKKLIRAIIEETC 1016
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 53-354 3.38e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 3.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      53 QYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLK-ALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLirtn 131
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSqELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL---- 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     132 ERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEK-ELLHSQNTWLNTELKTKTDELLA 210
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     211 LgrekgNEILELKcnLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKfHNELNAHIKLSNLYK 290
Cdd:TIGR02169  827 E-----KEYLEKE--IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR-LGDLKKERDELEAQL 898

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1850342     291 SAAddsEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEK--IGRLEKELE 354
Cdd:TIGR02169  899 REL---ERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsLEDVQAELQ 961
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
29-372 3.66e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.46  E-value: 3.66e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    29 LADQQSEIDGLKGRHEKF------KVESEQQYFEIEKRLSHSQERL---------VNETRECQSLRLELEKLNNQLKALT 93
Cdd:COG4717   73 LKELEEELKEAEEKEEEYaelqeeLEELEEELEELEAELEELREELeklekllqlLPLYQELEALEAELAELPERLEELE 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    94 EKNKELEIAQDRNIAIQSQFTRTKEELEAEKRdliRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQA-- 171
Cdd:COG4717  153 ERLEELRELEEELEELEAELAELQEELEELLE---QLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEel 229

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   172 ----SDVSVKYREKRLEQEKELL--------HSQNTWLNTELKTKTDELLALG---------------REKGNEILELKC 224
Cdd:COG4717  230 eqleNELEAAALEERLKEARLLLliaaallaLLGLGGSLLSLILTIAGVLFLVlgllallflllarekASLGKEAEELQA 309

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   225 NLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFH--NELNAHIKLSNLYKSAADDSEAKSNE 302
Cdd:COG4717  310 LPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEelQLEELEQEIAALLAEAGVEDEEELRA 389

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1850342   303 LTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEML-EKIGRLEKEL-ENANDLLSATKRKGAILSE 372
Cdd:COG4717  390 ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELeEELEELEEELeELEEELEELREELAELEAE 461
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1-274 1.07e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      1 MAAVLQQVLERTELNKLPKSVQNKLEKFLAdQQSEIDGLKGRHEKFKveseqqyfEIEKRLS-HSQERLVNETRECQSLR 79
Cdd:PRK03918  461 LKRIEKELKEIEEKERKLRKELRELEKVLK-KESELIKLKELAEQLK--------ELEEKLKkYNLEELEKKAEEYEKLK 531

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     80 LELEKLNNQLKALTEKNKELEIAQDRNIAIQSQftrtKEELEAEKRDLIRTNERLSQE-LEYLTEDVKRLNEKLKESNTT 158
Cdd:PRK03918  532 EKLIKLKGEIKSLKKELEKLEELKKKLAELEKK----LDELEEELAELLKELEELGFEsVEELEERLKELEPFYNEYLEL 607

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    159 KG---ELQLKLDELQASDVSVKYREKRLEQEKellhsqntwlnTELKTKTDELLALGREKGNEilelkcNLENKKEEVSR 235
Cdd:PRK03918  608 KDaekELEREEKELKKLEEELDKAFEELAETE-----------KRLEELRKELEELEKKYSEE------EYEELREEYLE 670

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1850342    236 LEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEK 274
Cdd:PRK03918  671 LSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKA 709
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 1640-1877 2.13e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 43.02  E-value: 2.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1640 EQQRQITLKTTPASGErgiaSTSDPPTANIKPTPVVSTPSKV---TAAAMAG----NKSTPRASIRPMVTPATVTNPTTT 1712
Cdd:pfam17823   89 EHTPHGTDLSEPATRE----GAADGAASRALAAAASSSPSSAaqsLPAAIAAlpseAFSAPRAAACRANASAAPRAAIAA 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1713 PTA----TVMPTTQVESQEAMQSEGPVEHVPVFGSTS---------GSVRSTSPNVQPSISQ-----PILTVQQQTQATA 1774
Cdd:pfam17823  165 ASAphaaSPAPRTAASSTTAASSTTAASSAPTTAASSapatltparGISTAATATGHPAAGTalaavGNSSPAAGTVTAA 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1775 FVQPTQQSHPQIEPANQELSSNIVEVVQSSPVER---PSTSTAVfGTVSATPSSSLpkrtREEEEDSTIEAS-DQVSDDT 1850
Cdd:pfam17823  245 VGTVTPAALATLAAAAGTVASAAGTINMGDPHARrlsPAKHMPS-DTMARNPAAPM----GAQAQGPIIQVStDQPVHNT 319

                          250       260
                   ....*....|....*....|....*..
gi 1850342    1851 VEMPLPKKLKSVTPVGTEEEVMAEEST 1877
Cdd:pfam17823  320 AGEPTPSPSNTTLEPNTPKSVASTNLA 346
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 5-272 5.15e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.41  E-value: 5.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342       5 LQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRlshsqerlVNETR-ECQSLRLELE 83
Cdd:pfam15921  543 LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKE--------INDRRlELQEFKILKD 614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      84 KLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNE----KLKESNTTK 159
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRnfrnKSEEMETTT 694

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     160 GELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALgrEKGNEILELKCNLENK-----KEEVS 234
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDAL--QSKIQFLEEAMTNANKekhflKEEKN 772

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1850342     235 RLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASME 272
Cdd:pfam15921  773 KLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
 
Name Accession Description Interval E-value
TPR_MLP1_2 pfam07926
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of ...
 1040-1166 2.40e-26

TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of human TPR protein and to yeast myosin-like proteins 1 (MLP1) and 2 (MLP2). These proteins share a number of features; for example, they all have coiled-coil regions and all three are associated with nuclear pores. TPR is thought to be a component of nuclear pore complex- attached intra-nuclear filaments, and is implicated in nuclear protein import. Moreover, its N-terminal region is involved in the activation of oncogenic kinases, possibly by mediating the dimerization of kinase domains or by targeting these kinases to the nuclear pore complex. MLP1 and MLP2 are involved in the process of telomere length regulation, where they are thought to interact with proteins such as Tel1p and modulate their activity.


Pssm-ID: 462316 [Multi-domain]  Cd Length: 129  Bit Score: 106.18  E-value: 2.40e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1040 LSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQK 1119
Cdd:pfam07926    3 LSSLQSEIKRLKEEAADAEAQLQKLQEDLEKQAEIAREAQQNYERELVLHAEDIKALQALREELNELKAEIAELKAEAES 82

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1850342    1120 AESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKL 1166
Cdd:pfam07926   83 AKAELEESEESWEEQKKELEKELSELEKRIEDLNEQNKLLHDQLESL 129
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 773-1619 2.68e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.52  E-value: 2.68e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     773 KLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRL---SSQIEKLEHEIS 849
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyalANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     850 HLKKKLENEVEQRhtltRNLDVQLLDTKRQLD-TETNLHLNTKEL------LKNAQKEIATLKRHLSNMEVQVASQSSQR 922
Cdd:TIGR02168  306 ILRERLANLERQL----EELEAQLEELESKLDeLAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     923 TGKgqpsnKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLnkEKQVTEEVRKNIEVRLKESAEFQT 1002
Cdd:TIGR02168  382 ETL-----RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL--EEAELKELQAELEELEEELEELQE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1003 QLEKKLMEVEKEKQELqDDKRRAIESMEQQLSELKKTLSSVQNEVQEA--LQRASTALSNEQQARRDCQEQAKIAVEAQN 1080
Cdd:TIGR02168  455 ELERLEEALEELREEL-EEAEQALDAAERELAQLQARLDSLERLQENLegFSEGVKALLKNQSGLSGILGVLSELISVDE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1081 KYEREL------MLHAADVEALQAAKEQVS---KMASVRQHLEETTQKAESQLleckaswEERERMLKDEVSKCVCRCED 1151
Cdd:TIGR02168  534 GYEAAIeaalggRLQAVVVENLNAAKKAIAflkQNELGRVTFLPLDSIKGTEI-------QGNDREILKNIEGFLGVAKD 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1152 LEKQNRLLHDQIEKLSDKVVasVKEGVQGPLNVslseegksQEQILEILRFIRREKEIAETRFEVAqveslryrqrvell 1231
Cdd:TIGR02168  607 LVKFDPKLRKALSYLLGGVL--VVDDLDNALEL--------AKKLRPGYRIVTLDGDLVRPGGVIT-------------- 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1232 erelqelqdslnaeREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDIlplqean 1311
Cdd:TIGR02168  663 --------------GGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEL------- 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1312 AELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDtEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTN 1391
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE-AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1392 N-------QNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKvmetsaqssg 1464
Cdd:TIGR02168  801 LrealdelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE---------- 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1465 dHQEQHVSVQ-EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQD---LQDRTTQEE 1540
Cdd:TIGR02168  871 -LESELEALLnERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRidnLQERLSEEY 949

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1541 QLRQQ--------ITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELdvriTALKSQYEGRISR 1612
Cdd:TIGR02168  950 SLTLEeaealenkIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDL----TEAKETLEEAIEE 1025


                   ....*..
gi 1850342    1613 LERELRE 1619
Cdd:TIGR02168 1026 IDREARE 1032
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 785-1649 6.09e-22

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 104.38  E-value: 6.09e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     785 KKEKEMLKLSEVRLSQQRESLLAEQRGQNLlltnlQTIQGilERSETETKQRLSSQIEKLE-HEISHLKKKLENEVEQRH 863
Cdd:TIGR02169  171 KKEKALEELEEVEENIERLDLIIDEKRQQL-----ERLRR--EREKAERYQALLKEKREYEgYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     864 TLTRNLDVQLLDTKRQLD--------TETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQrtgkgQPSNKEDVD 935
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISelekrleeIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERS-----IAEKERELE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     936 DLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEvrlKESAEFQTqLEKKLMEVEKEK 1015
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELE---EVDKEFAE-TRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1016 QELQDdKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKiaveaqnKYERELMLHAADVEA 1095
Cdd:TIGR02169  395 EKLKR-EINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIK-------KQEWKLEQLAADLSK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1096 lqaAKEQVSKMASVRQHLEETTQKAESQLLECKAS---WEERERMLKDEVskcvcrcEDLEKQNRLLHDQIEKLsdkvvA 1172
Cdd:TIGR02169  467 ---YEQELYDLKEEYDRVEKELSKLQRELAEAEAQaraSEERVRGGRAVE-------EVLKASIQGVHGTVAQL-----G 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1173 SVKEGVQGPL---------NVSLSEEGKSQEQIleilRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLN 1243
Cdd:TIGR02169  532 SVGERYATAIevaagnrlnNVVVEDDAVAKEAI----ELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVE 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1244 AEReKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQD--LQQMQAKVRKLELDILPLQEANAELSEKSGML 1321
Cdd:TIGR02169  608 FDP-KYEPAFKYVFGDTLVVEDIEAARRLMGKYRMVTLEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGL 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1322 QAEKKLLEEDVKRWKARnqhlvsqqkdpdTEEYRKLLSEKEvhtKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKE 1401
Cdd:TIGR02169  687 KRELSSLQSELRRIENR------------LDELSQELSDAS---RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ 751

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1402 DLNKVRTEKETIQKDLD---AKIIDIQEKVKTI------TQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVS 1472
Cdd:TIGR02169  752 EIENVKSELKELEARIEeleEDLHKLEEALNDLearlshSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1473 VQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEK 1552
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1553 TRKAIVAAKSKIAHLAGVKDQLTKENEELKQRN---------GALDQQKDELDVRITALKS-------QYEGRISRLErE 1616
Cdd:TIGR02169  912 IEKKRKRLSELKAKLEALEEELSEIEDPKGEDEeipeeelslEDVQAELQRVEEEIRALEPvnmlaiqEYEEVLKRLD-E 990

                          890       900       910
                   ....*....|....*....|....*....|...
gi 1850342    1617 LREHQERHLEQRDEPQEPSNKVPEQQRQITLKT 1649
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEEYEKKKREVFMEA 1023
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 672-1453 6.42e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 6.42e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     672 LKQLQEIFENYKKEKAENEKIQNE---QLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQK 748
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEEltaELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     749 LTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILER 828
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     829 SETETK---QRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTK-ELLKNAQKEIATL 904
Cdd:TIGR02168  394 QIASLNneiERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLeEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     905 KRHLSNMEVQVASQSSQRTG-KGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQY-QAMVTSLEESLNKEKQV 982
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSlERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYeAAIEAALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     983 TEE-VRKNIEVRLKESAEFQTQLEKKLMEvEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTA--LS 1059
Cdd:TIGR02168  554 NLNaAKKAIAFLKQNELGRVTFLPLDSIK-GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVddLD 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1060 NEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERmLK 1139
Cdd:TIGR02168  633 NALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEE-LE 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1140 DEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVvasvkEGVQGPLNVSLSEEGKSQEQILEilrfIRREKEIAETRFEVAQV 1219
Cdd:TIGR02168  712 EELEQLRKELEELSRQISALRKDLARLEAEV-----EQLEERIAQLSKELTELEAEIEE----LEERLEEAEEELAEAEA 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1220 ESLRYRQRVELLERELQELQDSLNAEREKVQvtaktmAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRK 1299
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELT------LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1300 LELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDtEEYRKLLSEKEVHTKRIQQLTEEIGRLK 1379
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE-SKRSELRRELEELREKLAQLELRLEGLE 935

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1850342    1380 AEIARSNASLTNNQNLiqSLKEDLNKVRtEKETIQKDLDAKIIDIQEKVKTITQVKKIG----RRYKTQYEELKAQQD 1453
Cdd:TIGR02168  936 VRIDNLQERLSEEYSL--TLEEAEALEN-KIEDDEEEARRRLKRLENKIKELGPVNLAAieeyEELKERYDFLTAQKE 1010
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 227-1066 3.01e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 3.01e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     227 ENKKEEVSRLEEqmnglktSNEHLQKhVEDLLTKLKEAK---EQQASMEEKFHnELNAHIK------LSNLYKSAADDSE 297
Cdd:TIGR02168  172 ERRKETERKLER-------TRENLDR-LEDILNELERQLkslERQAEKAERYK-ELKAELRelelalLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     298 AKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEqskdqmekEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAA 377
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVS--------ELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     378 MSPTAAAVAKIVKPGMKLTELynayvetqdQLLLEKLENKrinkyLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVK 457
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDEL---------AEELAELEEK-----LEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     458 LEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADissssevisqhl 537
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE------------ 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     538 vsyrnIEELQQQNQRLLVALRELgetreREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSiVRQRDMYRIL 617
Cdd:TIGR02168  449 -----LEELQEELERLEEALEEL-----REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG-VKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     618 LSQTTGVAIPLH--------------ASSLDDV---------SLASTPKRPSTSQTvsTPAPVPVIESTEAIEAKAALKQ 674
Cdd:TIGR02168  518 LSGILGVLSELIsvdegyeaaieaalGGRLQAVvvenlnaakKAIAFLKQNELGRV--TFLPLDSIKGTEIQGNDREILK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     675 LQEIFENYKKEKAE-NEKIQN------------EQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQdnveGYRREITS 741
Cdd:TIGR02168  596 NIEGFLGVAKDLVKfDPKLRKalsyllggvlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITG----GSAKTNSS 671

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     742 LHERNQKLTATTQKQEQiintMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEqrgqnllltnlqt 821
Cdd:TIGR02168  672 ILERRREIEELEEKIEE----LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD------------- 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     822 iqgilersetetKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLhlntKELLKNAQKEI 901
Cdd:TIGR02168  735 ------------LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL----EAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     902 ATLKRHLS--NMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN-- 977
Cdd:TIGR02168  799 KALREALDelRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEal 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     978 -KEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD---DKRRAIESMEQQLSELKKTLSSVQN-EVQEALQ 1052
Cdd:TIGR02168  879 lNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREklaQLELRLEGLEVRIDNLQERLSEEYSlTLEEAEA 958

                          890
                   ....*....|....
gi 1850342    1053 RASTALSNEQQARR 1066
Cdd:TIGR02168  959 LENKIEDDEEEARR 972
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 974-1640 5.31e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 5.31e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     974 ESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQ---DDKRRAIESMEQQLSELKKTLSSVQNEVQEA 1050
Cdd:TIGR02168  242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQkelYALANEISRLEQQKQILRERLANLERQLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1051 LQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKeqvSKMASVRQHLEeTTQKAESQLLECKAS 1130
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE---SRLEELEEQLE-TLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1131 WEERERMLKDEVskcvcrcEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGplnvSLSEEGKSQEQILEILRFIRREKEIA 1210
Cdd:TIGR02168  398 LNNEIERLEARL-------ERLEDRRERLQQEIEELLKKLEEAELKELQA----ELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1211 ETRFEVAQVESL-------RYRQRVELLERELQELQDSLNAEREKVQVtAKTMAQH-----------EELMKKTETM--- 1269
Cdd:TIGR02168  467 REELEEAEQALDaaerelaQLQARLDSLERLQENLEGFSEGVKALLKN-QSGLSGIlgvlselisvdEGYEAAIEAAlgg 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1270 ---NVVMETNKMLREEKERLEQDLqqmQAKVRKLELDILPLQEANAE----LSEKSGMLQAEKKLLEEDVKRWKARN--- 1339
Cdd:TIGR02168  546 rlqAVVVENLNAAKKAIAFLKQNE---LGRVTFLPLDSIKGTEIQGNdreiLKNIEGFLGVAKDLVKFDPKLRKALSyll 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1340 -QHLVSQQKDPDTEEYRKLLSEKEVHT---------------------------KRIQQLTEEIGRLKAEIARSNASLTN 1391
Cdd:TIGR02168  623 gGVLVVDDLDNALELAKKLRPGYRIVTldgdlvrpggvitggsaktnssilerrREIEELEEKIEELEEKIAELEKALAE 702

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1392 NQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKkigRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHV 1471
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE---ERIAQLSKELTELEAEIEELEERLEEAEEELAE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1472 SVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKE- 1550
Cdd:TIGR02168  780 AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAa 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1551 --EKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALK----------SQYEGRISRLERELR 1618
Cdd:TIGR02168  860 eiEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRreleelreklAQLELRLEGLEVRID 939

                          730       740
                   ....*....|....*....|...
gi 1850342    1619 EHQERHLEQ-RDEPQEPSNKVPE 1640
Cdd:TIGR02168  940 NLQERLSEEySLTLEEAEALENK 962
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 818-1644 3.74e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.49  E-value: 3.74e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     818 NLQTIQGILErsETETK-QRLSSQIEK------LEHEISHLKKKLE-NEVEQRHTLTRNLDVQLLDTKRQLDTETnlhln 889
Cdd:TIGR02168  187 NLDRLEDILN--ELERQlKSLERQAEKaerykeLKAELRELELALLvLRLEELREELEELQEELKEAEEELEELT----- 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     890 tkELLKNAQKEIATLKRHLSNMEVQVASQssqrtgkgqpsnKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMV 969
Cdd:TIGR02168  260 --AELQELEEKLEELRLEVSELEEEIEEL------------QKELYALANEISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     970 TSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVE------KEKQELQDDKRRAIESMEQQLSELKKTLSSV 1043
Cdd:TIGR02168  326 EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEelesrlEELEEQLETLRSKVAQLELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1044 QNEVqEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAAdVEALQAAKEQVSKMASVRQHLEETTQKAESQ 1123
Cdd:TIGR02168  406 EARL-ERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEEL-QEELERLEEALEELREELEEAEQALDAAERE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1124 LLECKASWEERERMLkDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVvaSVKEGVQGPLNVSLSE-----EGKSQEQILE 1198
Cdd:TIGR02168  484 LAQLQARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLSELI--SVDEGYEAAIEAALGGrlqavVVENLNAAKK 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1199 ILRFIRrEKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAK--------------TMAQHEELMK 1264
Cdd:TIGR02168  561 AIAFLK-QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvdDLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1265 KT--ETMNVVME-----------------TNKML--REEKERLEQDLQQMQAKVRKLEldilplqeanAELSEKSGMLQA 1323
Cdd:TIGR02168  640 KLrpGYRIVTLDgdlvrpggvitggsaktNSSILerRREIEELEEKIEELEEKIAELE----------KALAELRKELEE 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1324 EKKLLEEDVKRWKARNQHLVSQQKDpdteeYRKLLSEKEVHTKRIQQLTEEIGRLKAEIArsnasltnnqnliqSLKEDL 1403
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKD-----LARLEAEVEQLEERIAQLSKELTELEAEIE--------------ELEERL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1404 NKVRTEKETIQKDLdakiidiqekvktitqvkkigrryktqyEELKAQQDKVMETSAQSSGDHQEQHvsvQEMQELKETL 1483
Cdd:TIGR02168  771 EEAEEELAEAEAEI----------------------------EELEAQIEQLKEELKALREALDELR---AELTLLNEEA 819

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1484 NQAETKskslesqVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSK 1563
Cdd:TIGR02168  820 ANLRER-------LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALL 892

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1564 IAHLagvkDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEG---RISRLERELREHQErhLEQRDEPQEPSNKVPE 1640
Cdd:TIGR02168  893 RSEL----EELSEELRELESKRSELRRELEELREKLAQLELRLEGlevRIDNLQERLSEEYS--LTLEEAEALENKIEDD 966


                   ....
gi 1850342    1641 QQRQ 1644
Cdd:TIGR02168  967 EEEA 970
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 56-1053 9.14e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 9.14e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      56 EIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKAlTEKNKELEiAQDRNIAIQSQFTRtKEELEAEKRDLIRTNERLS 135
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKSLERQAEK-AERYKELK-AELRELELALLVLR-LEELREELEELQEELKEAE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     136 QELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREK 215
Cdd:TIGR02168  253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     216 gneilelkcnlENKKEEVSRLEEqmnglktsnehlqkhvedlltKLKEAKEQQASMEEKFhnelnahiklsnlyksaadd 295
Cdd:TIGR02168  333 -----------DELAEELAELEE---------------------KLEELKEELESLEAEL-------------------- 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     296 seaksneltravEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEmlekIGRLEKELENANDLLSATKRKGAILSEEel 375
Cdd:TIGR02168  361 ------------EELEAELEELESRLEELEEQLETLRSKVAQLELQ----IASLNNEIERLEARLERLEDRRERLQQE-- 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     376 aamsptaaavakivkpgmkLTELYNAYVETQDQLLLEKLEnkRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLS 455
Cdd:TIGR02168  423 -------------------IEELLKKLEEAELKELQAELE--ELEEELEELQEELERLEEALEELREELEEAEQALDAAE 481

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     456 VKLEQAMKEI---QRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRV-------LLMELEEARGNHVIRDEEVssad 525
Cdd:TIGR02168  482 RELAQLQARLdslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVdegyeaaIEAALGGRLQAVVVENLNA---- 557

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     526 ISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSkitelqlkLESALTELEQLRKSRQHQMQLVD 605
Cdd:TIGR02168  558 AKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD--------LVKFDPKLRKALSYLLGGVLVVD 629

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     606 SIVRQRDMYRILLSQTTGVaiplhasSLDDVSLastpkrpsTSQTVSTPAPVPVIESTeaIEAKAALKQLQEIFEnykkE 685
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIV-------TLDGDLV--------RPGGVITGGSAKTNSSI--LERRREIEELEEKIE----E 688

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     686 KAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQ 765
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     766 DLRGANEKLAVAEIRAENLKKEKEMLKLsevRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETK------QRLSS 839
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKE---ELKALREALDELRAELTLLNEEAANLRERLESLERRIAaterrlEDLEE 845

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     840 QIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLldtkrqldtetnlhlntkELLKNAQKEIATLKRHLSNMEVQVASQS 919
Cdd:TIGR02168  846 QIEELSEDIESLAAEIEELEELIEELESELEALL------------------NERASLEEALALLRSELEELSEELRELE 907

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     920 SQRtgkgqpsnkedvDDLVSQLRQTEEQVNDLKERLktstsnvEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAE 999
Cdd:TIGR02168  908 SKR------------SELRRELEELREKLAQLELRL-------EGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE 968

                          970       980       990      1000      1010
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1850342    1000 fqtQLEKKLMEVEKEKQELQDDKRRAIESMEqQLSELKKTLSSVQNEVQEALQR 1053
Cdd:TIGR02168  969 ---EARRRLKRLENKIKELGPVNLAAIEEYE-ELKERYDFLTAQKEDLTEAKET 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 27-884 5.81e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 5.81e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      27 KFLADQQSEID-GLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKlnnqlkALTEKNKELEIAQDR 105
Cdd:TIGR02168  216 KELKAELRELElALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL------EVSELEEEIEELQKE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     106 NIAIQSQftrtKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQ 185
Cdd:TIGR02168  290 LYALANE----ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     186 EKELLHSQNTWLNTELktktdellalgREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAK 265
Cdd:TIGR02168  366 ELEELESRLEELEEQL-----------ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     266 EQQASMEEKFHNElnahiklsnlyksAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEM--L 343
Cdd:TIGR02168  435 LKELQAELEELEE-------------ELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQenL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     344 EKIGRLEKELENANDLLSATK-RKGAILSEEE------LAAMSPTAAAVAkivkpgMKLTELYNAYVETQDQ-------- 408
Cdd:TIGR02168  502 EGFSEGVKALLKNQSGLSGILgVLSELISVDEgyeaaiEAALGGRLQAVV------VENLNAAKKAIAFLKQnelgrvtf 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     409 LLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASL------SVKLEQAMKEIQRLQEDTD--------- 473
Cdd:TIGR02168  576 LPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDNALELAKKLRPGYRivtldgdlv 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     474 ---------KANKQSSVLERDN--RRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYR- 541
Cdd:TIGR02168  656 rpggvitggSAKTNSSILERRReiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDl 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     542 NIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIvrqRDMYRILLSQT 621
Cdd:TIGR02168  736 ARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL---REALDELRAEL 812

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     622 TGVAIPLHASSLDDVSLastpkrpstsqtvstpapvpvieSTEAIEAKAALKQLQEIFENykkekaenekiQNEQLEKLQ 701
Cdd:TIGR02168  813 TLLNEEAANLRERLESL-----------------------ERRIAATERRLEDLEEQIEE-----------LSEDIESLA 858

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     702 EQVTDLRSQNTKISTQLDFASKRYEMLQdnvegyrREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRA 781
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNERASLE-------EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     782 ENLkkekemlklsEVRLSQQRESLLAEqrgQNLLLTNLQTIQGILERSETETKQRLSS---QIEKL-------EHEISHL 851
Cdd:TIGR02168  932 EGL----------EVRIDNLQERLSEE---YSLTLEEAEALENKIEDDEEEARRRLKRlenKIKELgpvnlaaIEEYEEL 998

                          890       900       910
                   ....*....|....*....|....*....|...
gi 1850342     852 KKKLENEVEQRHTLTRNLDvQLLDTKRQLDTET 884
Cdd:TIGR02168  999 KERYDFLTAQKEDLTEAKE-TLEEAIEEIDREA 1030
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 667-1628 6.72e-15

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 81.25  E-value: 6.72e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     667 EAKAALKQLQEIFENYKKEKAEN--EKIQNEQLEKLQEQVTDLR------SQNTKISTQLDFASKRYEMLQDNVEGYRRE 738
Cdd:TIGR00606  167 EGKALKQKFDEIFSATRYIKALEtlRQVRQTQGQKVQEHQMELKylkqykEKACEIRDQITSKEAQLESSREIVKSYENE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     739 ITSLHERNQKLTATTQKQEQIINTMTQdlrganekLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTN 818
Cdd:TIGR00606  247 LDPLKNRLKEIEHNLSKIMKLDNEIKA--------LKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     819 LQTIQGILERSETETKQRLSSQiEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELlknaq 898
Cdd:TIGR00606  319 RELVDCQRELEKLNKERRLLNQ-EKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQI----- 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     899 KEIATLKRHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNK 978
Cdd:TIGR00606  393 KNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDR 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     979 EKQVTEEVRKNI-EVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQqLSELKKTLSSVQNEVQEALQRASTA 1057
Cdd:TIGR00606  473 ILELDQELRKAErELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQ-LNHHTTTRTQMEMLTKDKMDKDEQI 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1058 LSNEQQARRDCQEQAKiavEAQNKYERELMLHAADVEALQAaKEQVSKMASVRQHLEETTQKAESQLleckASWEERERM 1137
Cdd:TIGR00606  552 RKIKSRHSDELTSLLG---YFPNKKQLEDWLHSKSKEINQT-RDRLAKLNKELASLEQNKNHINNEL----ESKEEQLSS 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1138 LKDEVSKcVCRCEDLEKQNRLLHDQIEKLS-DKVVASVKEGVQGPLNVSLSEEGKSQEQILEilRFIRREKEIAETrfev 1216
Cdd:TIGR00606  624 YEDKLFD-VCGSQDEESDLERLKEEIEKSSkQRAMLAGATAVYSQFITQLTDENQSCCPVCQ--RVFQTEAELQEF---- 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1217 aqVESLRYRQRVELLERELQELQDSlNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQak 1296
Cdd:TIGR00606  697 --ISDLQSKLRLAPDKLKSTESELK-KKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQE-- 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1297 vrKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIG 1376
Cdd:TIGR00606  772 --TLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNR 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1377 RLKAEiarsnasltnNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEEL----KAQQ 1452
Cdd:TIGR00606  850 KLIQD----------QQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDspleTFLE 919

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1453 DKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQV-ENLQKTLSEKETEARNL-------QEQTVQLQSE 1524
Cdd:TIGR00606  920 KDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIqDGKDDYLKQKETELNTVnaqleecEKHQEKINED 999

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1525 LSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDElDVRITALKS 1604
Cdd:TIGR00606 1000 MRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRN-HVLALGRQK 1078

                          970       980
                   ....*....|....*....|....
gi 1850342    1605 QYEGRISRLERELREHQERHLEQR 1628
Cdd:TIGR00606 1079 GYEKEIKHFKKELREPQFRDAEEK 1102
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 671-1338 2.05e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.72  E-value: 2.05e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     671 ALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLT 750
Cdd:TIGR02168  292 ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     751 ATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQrgQNLLLTNLQTIQGILERSE 830
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL--EEAELKELQAELEELEEEL 449

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     831 TETKQRLSSQIEKLEhEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSN 910
Cdd:TIGR02168  450 EELQEELERLEEALE-ELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL 528

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     911 MEVQ-----------------------------VASQSSQRTGKGQ--PSNKEDVDDLVSQLRQTEEQVNDLKERLKTST 959
Cdd:TIGR02168  529 ISVDegyeaaieaalggrlqavvvenlnaakkaIAFLKQNELGRVTflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     960 SNVEQYQ----------AMVTSLEESLNKEKQVTEEVR---------------------------------KNIEVRLKE 996
Cdd:TIGR02168  609 KFDPKLRkalsyllggvLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktnssilerrreiEELEEKIEE 688

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     997 SAEFQTQLEKKLMEVEKEKQELQD---DKRRAIESMEQQLSELKKTLSSVQNEVQEALQRastalsNEQQARRDCQEQAK 1073
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEeleQLRKELEELSRQISALRKDLARLEAEVEQLEER------IAQLSKELTELEAE 762

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1074 IAVEAQNKYERELMLHAADVEaLQAAKEQVSKMASVRQHLEETTQKAESQLLECKasweERERMLKDEVSKCVCRCEDLE 1153
Cdd:TIGR02168  763 IEELEERLEEAEEELAEAEAE-IEELEAQIEQLKEELKALREALDELRAELTLLN----EEAANLRERLESLERRIAATE 837

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1154 KQNRLLHDQIEKLSDKVVAsvkegvqgpLNVSLSEEGKSQEQIleilrfirrEKEIAETRFEVAQVESLRYRQRveller 1233
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIES---------LAAEIEELEELIEEL---------ESELEALLNERASLEEALALLR------ 893

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1234 elqelqdslnaerekvqvtaktmaqhEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEA-NA 1312
Cdd:TIGR02168  894 --------------------------SELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSE 947

                          730       740
                   ....*....|....*....|....*.
gi 1850342    1313 ELSEKSGMLQAEKKLLEEDVKRWKAR 1338
Cdd:TIGR02168  948 EYSLTLEEAEALENKIEDDEEEARRR 973
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 36-620 8.18e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 8.18e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    36 IDGLKGRHEKFKVESEQ--QYFEIEKRLshsqerlvnETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIA----I 109
Cdd:COG1196  195 LGELERQLEPLERQAEKaeRYRELKEEL---------KELEAELLLLKLRELEAELEELEAELEELEAELEELEAelaeL 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   110 QSQFTRTKEELEAEKRDLIRTNER---LSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQE 186
Cdd:COG1196  266 EAELEELRLELEELELELEEAQAEeyeLLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   187 KELLHSQNTWLNTELKTKTDELLALGREKGNEILElkcnLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKE 266
Cdd:COG1196  346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE----LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   267 QQASMEEkfhnelnahiklsnlyksAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKI 346
Cdd:COG1196  422 ELEELEE------------------ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   347 GRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRinkyldei 426
Cdd:COG1196  484 EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED-------- 555

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   427 vkEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLME 506
Cdd:COG1196  556 --DEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   507 leeaRGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESA 586
Cdd:COG1196  634 ----AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                        570       580       590
                 ....*....|....*....|....*....|....
gi 1850342   587 LTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQ 620
Cdd:COG1196  710 AEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1353-1659 8.46e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 8.46e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1353 EYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASltnnqnlIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTIT 1432
Cdd:COG1196  233 KLRELEAELEELEAELEELEAELEELEAELAELEAE-------LEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1433 QVKKIGRRYKTQYEELKAQQDkvmETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEAR 1512
Cdd:COG1196  306 RLEERRRELEERLEELEEELA---ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1513 NLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEktrkAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQK 1592
Cdd:COG1196  383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE----ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1850342  1593 DELDVRITALKSQYEGRISRLERELREHQErhLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIA 1659
Cdd:COG1196  459 EALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 667-1301 1.62e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.51  E-value: 1.62e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   667 EAKAALK--QLQEIFENYKKEKAENE-KIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLH 743
Cdd:COG1196  208 QAEKAERyrELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ 287

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   744 ERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQrgqnllltnlqtiq 823
Cdd:COG1196  288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL-------------- 353

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   824 gilersetetkqrlssqiEKLEHEISHLKKKLENEVEQRHTLTRnldvQLLDTKRQLDTETNLHLNTKELLKNAQKEIAT 903
Cdd:COG1196  354 ------------------EEAEAELAEAEEALLEAEAELAEAEE----ELEELAEELLEALRAAAELAAQLEELEEAEEA 411

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   904 LKRHLSNMEvqvasqssqrtgkgqpsnkEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVT 983
Cdd:COG1196  412 LLERLERLE-------------------EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   984 EEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQ 1063
Cdd:COG1196  473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1064 ARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRqhleettqkaESQLLECKASWEERERMLKDEVS 1143
Cdd:COG1196  553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA----------AVDLVASDLREADARYYVLGDTL 622

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1144 KCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLR 1223
Cdd:COG1196  623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1850342  1224 YRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLE 1301
Cdd:COG1196  703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 413-1174 1.69e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 1.69e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     413 KLENKRIN-KYLDEIVKEVEAKAPILKRQ----------REEYERAQKAVASLSvkLEQAMKEIQRLQEDTDKANKQSSV 481
Cdd:TIGR02168  180 KLERTRENlDRLEDILNELERQLKSLERQaekaerykelKAELRELELALLVLR--LEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     482 LERDNRRMEIQVKDLSQQIRVLLMELEEARG---NHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALR 558
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKelyALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     559 ELgetrereeqETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTgvaiplhassLDDVSL 638
Cdd:TIGR02168  338 EL---------AELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE----------LQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     639 ASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQ------NEQLEKLQEQVTDLRSQNT 712
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQeelerlEEALEELREELEEAEQALD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     713 KISTQLDFASKRYEMLQD---NVEGYRREITSLHERNQKLTATTQKQEQIINT-------MTQDLRGANEKLAV----AE 778
Cdd:TIGR02168  479 AAERELAQLQARLDSLERlqeNLEGFSEGVKALLKNQSGLSGILGVLSELISVdegyeaaIEAALGGRLQAVVVenlnAA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     779 IRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQnlLLTNLQTIQGILERSETeTKQRLSSQIEKLeheISHLK--KKLE 856
Cdd:TIGR02168  559 KKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDRE--ILKNIEGFLGVAKDLVK-FDPKLRKALSYL---LGGVLvvDDLD 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     857 NEVEQRHTLTRNLDVQLLD----------TKRQLDTETNLhLNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQRTGKg 926
Cdd:TIGR02168  633 NALELAKKLRPGYRIVTLDgdlvrpggviTGGSAKTNSSI-LERRREIEELEEKIEELEEKIAELEKALAELRKELEEL- 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     927 qpsnKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEvrlkesaefqtQLEK 1006
Cdd:TIGR02168  711 ----EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE-----------EAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1007 KLMEVEKEKQELQDDkrraIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERel 1086
Cdd:TIGR02168  776 ELAEAEAEIEELEAQ----IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE-- 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1087 mlhaadvealqaAKEQVSKMASVRQHLEETTQKAESQL---LECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQI 1163
Cdd:TIGR02168  850 ------------LSEDIESLAAEIEELEELIEELESELealLNERASLEEALALLRSELEELSEELRELESKRSELRREL 917

                          810
                   ....*....|.
gi 1850342    1164 EKLSDKVVASV 1174
Cdd:TIGR02168  918 EELREKLAQLE 928
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 837-1384 4.26e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 4.26e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   837 LSSQIEKLE---------HEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRH 907
Cdd:COG1196  198 LERQLEPLErqaekaeryRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   908 LSNMEVQVASQSSQRtgkgqpsnkedvddLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVR 987
Cdd:COG1196  278 ELELELEEAQAEEYE--------------LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELE 343

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   988 ---KNIEVRLKESAEFQTQLEKKLMEVEK---EKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNE 1061
Cdd:COG1196  344 eelEEAEEELEEAEAELAEAEEALLEAEAelaEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL 423

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1062 QQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKAS-WEERERMLKD 1140
Cdd:COG1196  424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARlLLLLEAEADY 503

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1141 EVSKCVCRCEDLEKQNRLLHDQI------EKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQIL----------------E 1198
Cdd:COG1196  504 EGFLEGVKAALLLAGLRGLAGAVavligvEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLkaakagratflpldkiR 583

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1199 ILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAERE----------KVQVTAKTMAQHEELMKKTET 1268
Cdd:COG1196  584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLeaalrravtlAGRLREVTLEGEGGSAGGSLT 663

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1269 MNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKD 1348
Cdd:COG1196  664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743

                        570       580       590
                 ....*....|....*....|....*....|....*.
gi 1850342  1349 PDTEEYRKLLSEKEVhTKRIQQLTEEIGRLKAEIAR 1384
Cdd:COG1196  744 EEELLEEEALEELPE-PPDLEELERELERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 930-1644 4.62e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.56  E-value: 4.62e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    930 NKEDVDDLVSQLRQTEEQVNDLkERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEfQTQLEKKLM 1009
Cdd:PTZ00121 1048 IDEDIDGNHEGKAEAKAHVGQD-EGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARK-AEEAKKKAE 1125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1010 EVEK-EKQELQDDKRRAIESMEQQlselkktlssvQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELML 1088
Cdd:PTZ00121 1126 DARKaEEARKAEDARKAEEARKAE-----------DAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELR 1194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1089 HAADVEALQAAK--EQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKL 1166
Cdd:PTZ00121 1195 KAEDARKAEAARkaEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA 1274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1167 SDKVVAsvkEGVQGPLNVSLSEEGKSQEQIleilrfiRREKEIAETRFEVAQVESLRYRQRVELLERELQELQdslnAER 1246
Cdd:PTZ00121 1275 EEARKA---DELKKAEEKKKADEAKKAEEK-------KKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKK----AEE 1340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1247 EKVQVTAKTmAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLElDILPLQEANAELSEKSGMLQAEKK 1326
Cdd:PTZ00121 1341 AKKAAEAAK-AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD-EAKKKAEEDKKKADELKKAAAAKK 1418

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1327 LLEEDVKRWKARNQHLVSQQKdpdTEEYRKllsEKEVHTKRIQQLTEEIGRLKAEIARSnasltnnqnlIQSLKEDLNKV 1406
Cdd:PTZ00121 1419 KADEAKKKAEEKKKADEAKKK---AEEAKK---ADEAKKKAEEAKKAEEAKKKAEEAKK----------ADEAKKKAEEA 1482

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1407 RTEKETIQKDLDAKiiDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQA 1486
Cdd:PTZ00121 1483 KKADEAKKKAEEAK--KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKA 1560

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1487 ETKSKSLESQVENLQKTLSEKETE-ARNLQEQTVQLQSELSRLRQDL---QDRTTQEEQLRQQITEKEEKTRKAIVAAKS 1562
Cdd:PTZ00121 1561 EEKKKAEEAKKAEEDKNMALRKAEeAKKAEEARIEEVMKLYEEEKKMkaeEAKKAEEAKIKAEELKKAEEEKKKVEQLKK 1640

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1563 KIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQE-RHLEQRDEPQEPSNKVPEQ 1641
Cdd:PTZ00121 1641 KEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEaKKAEELKKKEAEEKKKAEE 1720


                  ...
gi 1850342   1642 QRQ 1644
Cdd:PTZ00121 1721 LKK 1723
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 53-595 7.90e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 7.90e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    53 QYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNE 132
Cdd:COG1196  233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   133 RLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAS-DVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLAL 211
Cdd:COG1196  313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEElEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   212 GR--EKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLY 289
Cdd:COG1196  393 RAaaELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   290 KSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAI 369
Cdd:COG1196  473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   370 LSEEELAAMSPTAAAVAKI----------VKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKR 439
Cdd:COG1196  553 VEDDEVAAAAIEYLKAAKAgratflpldkIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   440 QREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDE 519
Cdd:COG1196  633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   520 EVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLES-------ALTELEQ 592
Cdd:COG1196  713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAlgpvnllAIEEYEE 792


                 ...
gi 1850342   593 LRK 595
Cdd:COG1196  793 LEE 795
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 973-1619 1.95e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.05  E-value: 1.95e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   973 EESLNKEKQVTEEVRKNIEvRLKESAE----FQtQLEKKLMEVEKEKQELQDDKRRA-IESMEQQLSELKKTLSSVQNEV 1047
Cdd:COG1196  185 EENLERLEDILGELERQLE-PLERQAEkaerYR-ELKEELKELEAELLLLKLRELEAeLEELEAELEELEAELEELEAEL 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1048 QE---ALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQvskMASVRQHLEETTQKAESQL 1124
Cdd:COG1196  263 AEleaELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE---LEEELAELEEELEELEEEL 339

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1125 LECKASWEERERMLKDEVskcvcrcEDLEKQNRLLHDQIEKLSDKVVAsvkegvqgplnvsLSEEGKSQEQILEILRFIR 1204
Cdd:COG1196  340 EELEEELEEAEEELEEAE-------AELAEAEEALLEAEAELAEAEEE-------------LEELAEELLEALRAAAELA 399

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1205 REKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTEtmnvvmETNKMLREEKE 1284
Cdd:COG1196  400 AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL------ELLAELLEEAA 473

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1285 RLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDvKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVH 1364
Cdd:COG1196  474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR-GLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1365 TKRIQQLTEEIGRLKAEIA-RSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIG--RRY 1441
Cdd:COG1196  553 VEDDEVAAAAIEYLKAAKAgRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLvaARL 632

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1442 KTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQL 1521
Cdd:COG1196  633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEA 712

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1522 QSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTK---------------------ENEE 1580
Cdd:COG1196  713 EEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERelerlereiealgpvnllaieEYEE 792

                        650       660       670
                 ....*....|....*....|....*....|....*....
gi 1850342  1581 LKQRNGALDQQKDELDVRITALksqyEGRISRLERELRE 1619
Cdd:COG1196  793 LEERYDFLSEQREDLEEARETL----EEAIEEIDRETRE 827
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
26-612 2.22e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 72.79  E-value: 2.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     26 EKFLADQQSEIDGLKGRHEKFKVESEqqyfEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEiaqdr 105
Cdd:PRK03918  164 YKNLGEVIKEIKRRIERLEKFIKRTE----NIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE----- 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    106 niaiqsqftRTKEELEAEKRdlirtnerlsqELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQasdvsvkyrekrlEQ 185
Cdd:PRK03918  235 ---------ELKEEIEELEK-----------ELESLEGSKRKLEEKIRELEERIEELKKEIEELE-------------EK 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    186 EKELlhsqntwlnTELKTKTDELLALGREKgNEILELKCNLEnkkEEVSRLEEQMNGLktsnEHLQKHVEDLLTKLKEAK 265
Cdd:PRK03918  282 VKEL---------KELKEKAEEYIKLSEFY-EEYLDELREIE---KRLSRLEEEINGI----EERIKELEEKEERLEELK 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    266 EQQASMEEKFhNELNAHIKLSNLYKSAADDSEAKSNELT-RAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEmle 344
Cdd:PRK03918  345 KKLKELEKRL-EELEERHELYEEAKAKKEELERLKKRLTgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE--- 420

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    345 kigrlEKELENANDLLSATKRK----GAILSEEE-LAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRI 419
Cdd:PRK03918  421 -----IKELKKAIEELKKAKGKcpvcGRELTEEHrKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEL 495

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    420 NKYLD--EIVKEVEAK-----APILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEdtdkANKQSSVLERDNRRMEIQ 492
Cdd:PRK03918  496 IKLKElaEQLKELEEKlkkynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE----LKKKLAELEKKLDELEEE 571

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    493 VKDLSQQIRVL-----------LMELEEARGNHV-IRDEEVSSADISSSSEVISQHLV-SYRNIEELQQQNQRLLVALRE 559
Cdd:PRK03918  572 LAELLKELEELgfesveeleerLKELEPFYNEYLeLKDAEKELEREEKELKKLEEELDkAFEELAETEKRLEELRKELEE 651

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1850342    560 LGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRD 612
Cdd:PRK03918  652 LEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704
PTZ00121 PTZ00121
MAEBL; Provisional
 979-1632 8.61e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 71.33  E-value: 8.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    979 EKQVTEEVRKNIEVRLKESAEfQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTAL 1058
Cdd:PTZ00121 1186 EVRKAEELRKAEDARKAEAAR-KAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAH 1264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1059 SNEQQARRDCQEQAKI-----AVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAEsqllECKASWEE 1133
Cdd:PTZ00121 1265 FARRQAAIKAEEARKAdelkkAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAD----AAKKKAEE 1340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1134 RERmlKDEVSKCvcrcEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETR 1213
Cdd:PTZ00121 1341 AKK--AAEAAKA----EAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAA 1414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1214 FEVAQVESLRYR-QRVELLERELQELQDSLNAEREKVQVTAKTMAqhEELMKKTETMNVVMETNKMLREEKERLEQDLQQ 1292
Cdd:PTZ00121 1415 AAKKKADEAKKKaEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA--EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKA 1492

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1293 MQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRwKARNQHLVSQQKDPD----TEEYRKLLSEKEVHTKRI 1368
Cdd:PTZ00121 1493 EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK-KADEAKKAEEKKKADelkkAEELKKAEEKKKAEEAKK 1571

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1369 QQLTEEIGRLKAEIARSnaslTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIdiQEKVKTITQVKKIGRRYKTQYEEL 1448
Cdd:PTZ00121 1572 AEEDKNMALRKAEEAKK----AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK--AEELKKAEEEKKKVEQLKKKEAEE 1645

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1449 KAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQvenlqktLSEKETEARNLQEqtvqlqselsrL 1528
Cdd:PTZ00121 1646 KKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEA-------LKKEAEEAKKAEE-----------L 1707

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1529 RQDLQDRTTQEEQLRQqitEKEEKTRKAivaakskiahlagvkDQLTKENEELKQRNGALDQQKDELDvRITALKSQYEG 1608
Cdd:PTZ00121 1708 KKKEAEEKKKAEELKK---AEEENKIKA---------------EEAKKEAEEDKKKAEEAKKDEEEKK-KIAHLKKEEEK 1768

                         650       660
                  ....*....|....*....|....
gi 1850342   1609 RISRLERELREHQERHLEQRDEPQ 1632
Cdd:PTZ00121 1769 KAEEIRKEKEAVIEEELDEEDEKR 1792
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 872-1684 1.92e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 69.76  E-value: 1.92e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     872 QLLDTKRQLDTETNLHLNTKELLKNAqkeIATLKRHLSNMEVQVASQSSQRTGKGQpsNKEDVDDLVSQLRQTEEQVNDL 951
Cdd:pfam15921   86 QVKDLQRRLNESNELHEKQKFYLRQS---VIDLQTKLQEMQMERDAMADIRRRESQ--SQEDLRNQLQNTVHELEAAKCL 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     952 KE-RLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQT--------QLEKKLMEVEKEKQELQDdk 1022
Cdd:pfam15921  161 KEdMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTmhfrslgsAISKILRELDTEISYLKG-- 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1023 rrAIESMEQQLSELKktlSSVQNEVQEALQ----RASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLhaadveALQA 1098
Cdd:pfam15921  239 --RIFPVEDQLEALK---SESQNKIELLLQqhqdRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEI------IQEQ 307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1099 AKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLK-------DEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVV 1171
Cdd:pfam15921  308 ARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlanSELTEARTERDQFSQESGNLDDQLQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1172 ASVKE-GVQGPLNVSLSEEGKSQEQILEILRfirreKEIAETRFEVAQVESL--RYRQRVELLERELQELQDSLNAEREK 1248
Cdd:pfam15921  388 KREKElSLEKEQNKRLWDRDTGNSITIDHLR-----RELDDRNMEVQRLEALlkAMKSECQGQMERQMAAIQGKNESLEK 462

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1249 VQ-VTAKTMAQHEELMKKTETMNvvmeTNKMLREEKERLEQDLQ-QMQAKVRKLEldilplqEANAELSEksgmLQAEKK 1326
Cdd:pfam15921  463 VSsLTAQLESTKEMLRKVVEELT----AKKMTLESSERTVSDLTaSLQEKERAIE-------ATNAEITK----LRSRVD 527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1327 LLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQ-----QLTEEIGRLKAEIARSNASLTNNQNLIQSLKE 1401
Cdd:pfam15921  528 LKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQienmtQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ 607

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1402 DLNKVRTEKETIQKDLDAKIIDIQ-EKVKTITqvkkigrrykTQYEELKAQQDKVMETSaqssgdhqeqhvsvQEMQELK 1480
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLElEKVKLVN----------AGSERLRAVKDIKQERD--------------QLLNEVK 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1481 ETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQ-------LRQQITEKeekt 1553
Cdd:pfam15921  664 TSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHamkvamgMQKQITAK---- 739

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1554 RKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQ-------QKDELDVRITALKSQ---YEGRISRLERELREHQER 1623
Cdd:pfam15921  740 RGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQelstvatEKNKMAGELEVLRSQerrLKEKVANMEVALDKASLQ 819

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1850342    1624 HLEQRDEPQEPSNKVPEQQRQITLKTTPASGErGIASTSDPPTANIKPTPVVSTPSKVTAA 1684
Cdd:pfam15921  820 FAECQDIIQRQEQESVRLKLQHTLDVKELQGP-GYTSNSSMKPRLLQPASFTRTHSNVPSS 879
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 23-612 3.59e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 3.59e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      23 NKLEKFLADQQSEIDglkgRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIA 102
Cdd:TIGR02168  242 EELQEELKEAEEELE----ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     103 QDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKR 182
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     183 LEQEKELLHSQNTWLNTELKTKTDELLALGREKGN--------EILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHV 254
Cdd:TIGR02168  398 LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaelkelqaELEELEEELEELQEELERLEEALEELREELEEAEQAL 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     255 EDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKS---------NELTRAVEE-----LHKLLKEAGEA 320
Cdd:TIGR02168  478 DAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGvlselisvdEGYEAAIEAalggrLQAVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     321 NKAIQDHLLEVEQSK-----------DQMEKEMLEKIGRLEKELENANDLLSATKRK----GAILSEEELAAMSPTAAAV 385
Cdd:TIGR02168  558 AKKAIAFLKQNELGRvtflpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalSYLLGGVLVVDDLDNALEL 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     386 AKIVKPGMKLTEL-----------YNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASL 454
Cdd:TIGR02168  638 AKKLRPGYRIVTLdgdlvrpggviTGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQL 717

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     455 SVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGnHVIRDEEVSSADISSSSEVIS 534
Cdd:TIGR02168  718 RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE-ELAEAEAEIEELEAQIEQLKE 796

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     535 QHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSK-----------------------ITELQLKLESALTELE 591
Cdd:TIGR02168  797 ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATErrledleeqieelsedieslaaeIEELEELIEELESELE 876

                          650       660
                   ....*....|....*....|.
gi 1850342     592 QLRKSRQHQMQLVDSIVRQRD 612
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELE 897
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 19-507 4.25e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 68.51  E-value: 4.25e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      19 KSVQNKLEKFLADQQSEIDGLKGRHEKFK------VESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKal 92
Cdd:TIGR04523  172 ENELNLLEKEKLNIQKNIDKIKNKLLKLElllsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS-- 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      93 tEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQ---ELEYLTED-----VKRLNEKLKESNTTKGELQL 164
Cdd:TIGR04523  250 -NTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQlksEISDLNNQkeqdwNKELKSELKNQEKKLEEIQN 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     165 KLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKG----------NEILELKCNLENKKEEVS 234
Cdd:TIGR04523  329 QISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQsykqeiknleSQINDLESKIQNQEKLNQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     235 RLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFH------NELNAHIK--------LSNLYKSAADDSEAKS 300
Cdd:TIGR04523  409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSvkeliiKNLDNTREsletqlkvLSRSINKIKQNLEQKQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     301 NELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSK---DQMEKEMLEK---IGRLEKELENANDLLSATKRKGAILSEEE 374
Cdd:TIGR04523  489 KELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKekiEKLESEKKEKeskISDLEDELNKDDFELKKENLEKEIDEKNK 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     375 laamsptaaavaKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASL 454
Cdd:TIGR04523  569 ------------EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNI 636

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1850342     455 SVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMEL 507
Cdd:TIGR04523  637 KSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKEL 689
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 158-1049 5.32e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.46  E-value: 5.32e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     158 TKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLE 237
Cdd:pfam02463  150 MKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYL 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     238 EQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEA 317
Cdd:pfam02463  230 DYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     318 GEANKAIQDHLLEVEQSKDQMEKEMlEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVkpgmKLTE 397
Cdd:pfam02463  310 VDDEEKLKESEKEKKKAEKELKKEK-EEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK----LESE 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     398 LYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEakapILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANK 477
Cdd:pfam02463  385 RLSSAAKLKEEELELKSEEEKEAQLLLELARQLE----DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     478 QSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVAL 557
Cdd:pfam02463  461 LKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     558 RELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQrdmYRILLSQTTGVAIPLHASSLDDVS 637
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKS---IAVLEIDPILNLAQLDKATLEADE 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     638 LASTPKRPSTSQTVSTpapvpviESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQ 717
Cdd:pfam02463  618 DDKRAKVVEGILKDTE-------LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELA 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     718 LDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEiraENLKKEKEMLKLSEVR 797
Cdd:pfam02463  691 KEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEE---EEKSRLKKEEKEEEKS 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     798 LSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTK 877
Cdd:pfam02463  768 ELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     878 RQLDTETNLHLNTKELLKNAQKEIATLKRHLSN-MEVQVASQSSQRTGKGQpsnKEDVDDLVSQLRQTEEQVNDLKERLK 956
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLLKEEELEeQKLKDELESKEEKEKEE---KKELEEESQKLNLLEEKENEIEERIK 924

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     957 TSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQdDKRRAIESMEQQLSEL 1036
Cdd:pfam02463  925 EEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKE-ERYNKDELEKERLEEE 1003

                          890
                   ....*....|...
gi 1850342    1037 KKTLSSVQNEVQE 1049
Cdd:pfam02463 1004 KKKLIRAIIEETC 1016
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1-742 9.08e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 9.08e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342       1 MAAVLQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKV---ESEQQYFEIEKRLSHSQERLVNETRECQS 77
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAeleELEAELEELESRLEELEEQLETLRSKVAQ 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      78 LRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQftRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKesnt 157
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERLQQEIEE--LLKKLEEAELKELQAELEELEEELEELQEELERLEEALE---- 464

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     158 tkgELQLKLDELQASDVSVKYREKRLEQEKELLHSqntwlntelktktdeLLALGREKGNEILELKCNLENKKEEVSRLE 237
Cdd:TIGR02168  465 ---ELREELEEAEQALDAAERELAQLQARLDSLER---------------LQENLEGFSEGVKALLKNQSGLSGILGVLS 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     238 EQMN---GLKTSNEH-LQKHVEDLLTK-LKEAKEQQASMEEkfhnelNAHIKLSNLYKSAADDSEAKSNELTRAVEE--- 309
Cdd:TIGR02168  527 ELISvdeGYEAAIEAaLGGRLQAVVVEnLNAAKKAIAFLKQ------NELGRVTFLPLDSIKGTEIQGNDREILKNIegf 600

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     310 ---LHKLLKEAGEANKAIQDHLLEVeqskdqmekemlekigRLEKELENANDLLSATKRKGAILSEEelaamsptaaavA 386
Cdd:TIGR02168  601 lgvAKDLVKFDPKLRKALSYLLGGV----------------LVVDDLDNALELAKKLRPGYRIVTLD------------G 652

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     387 KIVKPGMKLTelyNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQ 466
Cdd:TIGR02168  653 DLVRPGGVIT---GGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIS 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     467 RLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGnHVIRDEEVSSADISSSSEVISQHLVSYRNIEEL 546
Cdd:TIGR02168  730 ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE-ELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     547 QQQNQRLLVALRELGETREREEQETTSSK--ITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDmyrILLSQTTGV 624
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATErrLEDLEEQIEELSEDIESLAAEIEELEELIEELESELE---ALLNERASL 885

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     625 AIPLHASSLDDVSLASTPKRpstsqtvstpapvpviESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQV 704
Cdd:TIGR02168  886 EEALALLRSELEELSEELRE----------------LESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEY 949

                          730       740       750
                   ....*....|....*....|....*....|....*...
gi 1850342     705 tdlrsqntkiSTQLDFASKRYEMLQDNVEGYRREITSL 742
Cdd:TIGR02168  950 ----------SLTLEEAEALENKIEDDEEEARRRLKRL 977
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 973-1646 9.31e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 9.31e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     973 EESLNKEKQVTEEVRKNIEvrlkeSAEFQTQLEKKLMEVEKEKQELQ-----------DDKRRAIESMEQQLSELKKTLS 1041
Cdd:TIGR02168  185 RENLDRLEDILNELERQLK-----SLERQAEKAERYKELKAELRELElallvlrleelREELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1042 SVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVS-KMASVRQHLEETtQKA 1120
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEaQLEELESKLDEL-AEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1121 ESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVasvkegvqgplnvslseegksqeQILEIL 1200
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-----------------------QLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1201 RFIRREKEIAETRFEVAQVESLRYRQRVELLERelqelqdslNAEREKVQVTAKTMAQHEELMKKTETMNVVMEtnkmlr 1280
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLK---------KLEEAELKELQAELEELEEELEELQEELERLE------ 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1281 eekERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQH-----LVSQQKDPDtEEYR 1355
Cdd:TIGR02168  461 ---EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgVLSELISVD-EGYE 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1356 K------------LLSEKEVHTKRIQQLTEEIGRLKAEI--------ARSNASLTNNQNLIQSLKEDLNKVRTEKETIQK 1415
Cdd:TIGR02168  537 AaieaalggrlqaVVVENLNAAKKAIAFLKQNELGRVTFlpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRK 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1416 DLDAkIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKEtlnqAETKSKSLES 1495
Cdd:TIGR02168  617 ALSY-LLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEE----LEEKIEELEE 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1496 QVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLT 1575
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE 771

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1850342    1576 KENEELKQRNGALDQQKDELDVRITALKSQYEgRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQIT 1646
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALRE-ALDELRAELTLLNEEAANLRERLESLERRIAATERRLE 841
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
44-493 5.46e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.09  E-value: 5.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     44 EKFKVESEQQYFEIEKRLShsqeRLVNETRECQSLRLELEKLNNQLKALTEKNKELEiaqdRNIAIQSQFTRTKEELEAE 123
Cdd:PRK03918  299 SEFYEEYLDELREIEKRLS----RLEEEINGIEERIKELEEKEERLEELKKKLKELE----KRLEELEERHELYEEAKAK 370

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    124 KRDLirtnERLSQELEYLTedVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKEllhsqntwlntELKT 203
Cdd:PRK03918  371 KEEL----ERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIE-----------ELKK 433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    204 KTDELLALGRE-----KGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHV--EDLLTKLKEAKEQQASMEEKFh 276
Cdd:PRK03918  434 AKGKCPVCGRElteehRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLkkESELIKLKELAEQLKELEEKL- 512

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    277 nelnahiklsnlyksaaddSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEK--EMLEKIGRLEKELE 354
Cdd:PRK03918  513 -------------------KKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKlaELEKKLDELEEELA 573

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    355 NANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKA 434
Cdd:PRK03918  574 ELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELE 653

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1850342    435 PIL-----KRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQssVLERDNRRMEIQV 493
Cdd:PRK03918  654 KKYseeeyEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEE--LEEREKAKKELEK 715
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1283-1623 6.67e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 64.66  E-value: 6.67e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1283 KERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLsEKE 1362
Cdd:TIGR04523  199 LELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQK-ELE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1363 VHTKRIQQLTEEIGRLKAEIarSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYK 1442
Cdd:TIGR04523  278 QNNKKIKELEKQLNQLKSEI--SDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1443 TQYEELKAQQDKvmetsaqssgDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQ 1522
Cdd:TIGR04523  356 SENSEKQRELEE----------KQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1523 SELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDvRITAL 1602
Cdd:TIGR04523  426 KEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELK-KLNEE 504

                          330       340
                   ....*....|....*....|.
gi 1850342    1603 KSQYEGRISRLERELREHQER 1623
Cdd:TIGR04523  505 KKELEEKVKDLTKKISSLKEK 525
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 678-1584 8.41e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 64.61  E-value: 8.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     678 IFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFA-SKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQ 756
Cdd:pfam02463  164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKkALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQ 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     757 EQIINTMTQDLRGANEKLAVAEIRAENLKKEKEM---LKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETEt 833
Cdd:pfam02463  244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEekeKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE- 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     834 KQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLldtKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEV 913
Cdd:pfam02463  323 KKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELE---KLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELEL 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     914 QvasqssqrtgkgqpSNKEDVDDLVSQLRQTEEqvNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQvteevrknievr 993
Cdd:pfam02463  400 K--------------SEEEKEAQLLLELARQLE--DLLKEEKKEELEILEEEEESIELKQGKLTEEKE------------ 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     994 lkesaefqTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAK 1073
Cdd:pfam02463  452 --------ELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGR 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1074 IAVEAQNKYERELMLHAADVEALQAAKEQVSKMAsVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLE 1153
Cdd:pfam02463  524 IISAHGRLGDLGVAVENYKVAISTAVIVEVSATA-DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1154 KQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLER 1233
Cdd:pfam02463  603 LNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQ 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1234 ELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAE 1313
Cdd:pfam02463  683 EKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEK 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1314 LSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIArsnaSLTNNQ 1393
Cdd:pfam02463  763 EEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKE----EELEEL 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1394 NLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSV 1473
Cdd:pfam02463  839 ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENE 918

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1474 --QEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQlqselsrlrqdlqdrttqeeqlrqqitEKEE 1551
Cdd:pfam02463  919 ieERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLL---------------------------AKEE 971

                          890       900       910
                   ....*....|....*....|....*....|...
gi 1850342    1552 KTRKAIVAAKSKIAHLAGVKDQLTKENEELKQR 1584
Cdd:pfam02463  972 LGKVNLMAIEEFEEKEERYNKDELEKERLEEEK 1004
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 889-1629 1.45e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 63.91  E-value: 1.45e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     889 NTKELLKNAQKEIATLKRHLSNMEVQVASQSSqRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAM 968
Cdd:TIGR00606  245 NELDPLKNRLKEIEHNLSKIMKLDNEIKALKS-RKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVD 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     969 VTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD---------------DKRRAIESMEQQL 1033
Cdd:TIGR00606  324 CQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATrleldgfergpfserQIKNFHTLVIERQ 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1034 SELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKM-ASVRQH 1112
Cdd:TIGR00606  404 EDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELdQELRKA 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1113 LEETTQKAESQLLECKASWEERERMLKDEVSKCVCR-CEDLEKQNRLLHDQIEKLS------DKVVASVKEGVQGPLN-V 1184
Cdd:TIGR00606  484 ERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKlDQEMEQLNHHTTTRTQMEMltkdkmDKDEQIRKIKSRHSDElT 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1185 SLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMK 1264
Cdd:TIGR00606  564 SLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLER 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1265 ktetmnvvmetnkmLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVS 1344
Cdd:TIGR00606  644 --------------LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPD 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1345 QQKDPDTEeYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIiDI 1424
Cdd:TIGR00606  710 KLKSTESE-LKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAK-VC 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1425 QEKVKTITQVkkigrryktqYEELKAQQDKVMETSAQSSGDHQEQHVsvqemQELKETLNQAETKSKSLESQVENLQKTL 1504
Cdd:TIGR00606  788 LTDVTIMERF----------QMELKDVERKIAQQAAKLQGSDLDRTV-----QQVNQEKQEKQHELDTVVSKIELNRKLI 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1505 SEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRkAIVAAKSKIAHLAGVKDQLTKENEELKQR 1584
Cdd:TIGR00606  853 QDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIR-EIKDAKEQDSPLETFLEKDQQEKEELISS 931

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*
gi 1850342    1585 NGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRD 1629
Cdd:TIGR00606  932 KETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKE 976
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
879-1447 1.83e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.16  E-value: 1.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    879 QLDTETNLHLNTKELLKNAQKEIATLKRHLS---NMEVQVASQSSQRTGKgqpsnKEDVDDLVSQLRQTEEQVNDLKERL 955
Cdd:PRK03918  156 GLDDYENAYKNLGEVIKEIKRRIERLEKFIKrteNIEELIKEKEKELEEV-----LREINEISSELPELREELEKLEKEV 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    956 KTstsnVEQYQAMVTSLE---ESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVE--KEKQELQDDKRRAIESME 1030
Cdd:PRK03918  231 KE----LEELKEEIEELEkelESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYL 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1031 QQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIaveaqnkyERELMLHAADVEALQAAKEQVSKMASVR 1110
Cdd:PRK03918  307 DELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKEL--------EKRLEELEERHELYEEAKAKKEELERLK 378

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1111 QHLE-ETTQKAESQLLECkaswEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDkvvASVKEGVQGPLNVSLSEE 1189
Cdd:PRK03918  379 KRLTgLTPEKLEKELEEL----EKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK---AKGKCPVCGRELTEEHRK 451

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1190 GKSQEQILEILRFIRREKEIAET----RFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVtaktmaqhEELMKK 1265
Cdd:PRK03918  452 ELLEEYTAELKRIEKELKEIEEKerklRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNL--------EELEKK 523

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1266 TETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAE--------------------- 1324
Cdd:PRK03918  524 AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesveeleerlkelepfyne 603

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1325 -------KKLLEEDVKRWKARNQHLVS-----QQKDPDTEEYRKLLSEKEVH--TKRIQQLTEEIGRLKAEIARSNASLT 1390
Cdd:PRK03918  604 ylelkdaEKELEREEKELKKLEEELDKafeelAETEKRLEELRKELEELEKKysEEEYEELREEYLELSRELAGLRAELE 683

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1850342   1391 NNQNLIQSLKEDLNKVRTEKETIQKdLDAKIIDIQEKVKTITQVKKIGRRYKTQYEE 1447
Cdd:PRK03918  684 ELEKRREEIKKTLEKLKEELEEREK-AKKELEKLEKALERVEELREKVKKYKALLKE 739
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1274-1645 1.83e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 63.12  E-value: 1.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1274 ETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEE 1353
Cdd:TIGR04523  243 EKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKK 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1354 YRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNaslTNNQNLIQSLKEDLNKVRTEKETIQ------KDLDAKIIDIQEK 1427
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSE---SENSEKQRELEEKQNEIEKLKKENQsykqeiKNLESQINDLESK 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1428 VKTITQVKKIG----RRYKTQYEELKAQQDKVMET--SAQSSGDHQEQHVSVQEM---------QELKETLNQAETKSKS 1492
Cdd:TIGR04523  400 IQNQEKLNQQKdeqiKKLQQEKELLEKEIERLKETiiKNNSEIKDLTNQDSVKELiiknldntrESLETQLKVLSRSINK 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1493 LESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKS-----KIAHL 1567
Cdd:TIGR04523  480 IKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKddfelKKENL 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1568 AGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQ----------YEGRISRLERELREHQERH---LEQRDEPQEP 1634
Cdd:TIGR04523  560 EKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEkkdlikeieeKEKKISSLEKELEKAKKENeklSSIIKNIKSK 639

                          410
                   ....*....|.
gi 1850342    1635 SNKVPEQQRQI 1645
Cdd:TIGR04523  640 KNKLKQEVKQI 650
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1279-1451 2.39e-09

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 59.94  E-value: 2.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1279 LREEKERLEQDLQQMQAKVRKLELDilpLQEANAELSEksgmLQAEKKLLEEDVKRWKARNQHLVSQQKD-PDTEEYRKL 1357
Cdd:COG1579   22 LEHRLKELPAELAELEDELAALEAR---LEAAKTELED----LEKEIKRLELEIEEVEARIKKYEEQLGNvRNNKEYEAL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1358 LSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTItqVKKI 1437
Cdd:COG1579   95 QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL--AAKI 172

                        170
                 ....*....|....
gi 1850342  1438 GRRYKTQYEELKAQ 1451
Cdd:COG1579  173 PPELLALYERIRKR 186
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 54-1122 2.88e-09

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 63.15  E-value: 2.88e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      54 YFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEK-----NKELEIaQDRNIAIQSQFTRTKEELE--AEKRD 126
Cdd:TIGR01612  539 YKEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEikdlfDKYLEI-DDEIIYINKLKLELKEKIKniSDKNE 617

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     127 LIRTNERLSQELE----YLTEDVK----RLNEKLKESNTTKGELQLKLDELQASDVSVKYRE-KRLEQEKELLHSQNTWL 197
Cdd:TIGR01612  618 YIKKAIDLKKIIEnnnaYIDELAKispyQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYNElSSIVKENAIDNTEDKAK 697

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     198 NTELKTKTDELLALGREKGNEILELK-CNLENKKEEVSRLEEQMNGLKTS--NEHLQKHVEDLLTKLKE--------AKE 266
Cdd:TIGR01612  698 LDDLKSKIDKEYDKIQNMETATVELHlSNIENKKNELLDIIVEIKKHIHGeiNKDLNKILEDFKNKEKElsnkindyAKE 777

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     267 QQ-----ASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAV----EELHKLLKEAgeanKAIQDHLLEVEQSKDQ 337
Cdd:TIGR01612  778 KDelnkyKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTIsikeDEIFKIINEM----KFMKDDFLNKVDKFIN 853

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     338 MEKEMLEKIgrlEKELENANDLLSATKRKgaiLSEEELA----AMSPTAAAVAKIVKPGMKLTELYNAYVETQDQL---- 409
Cdd:TIGR01612  854 FENNCKEKI---DSEHEQFAELTNKIKAE---ISDDKLNdyekKFNDSKSLINEINKSIEEEYQNINTLKKVDEYIkice 927

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     410 ----LLEKLENKR--INKYLDEIVKEVEAKAPILKRQREEYERA--------QKAVASLSV-----KLEQAMKEIQRLQE 470
Cdd:TIGR01612  928 ntkeSIEKFHNKQniLKEILNKNIDTIKESNLIEKSYKDKFDNTlidkinelDKAFKDASLndyeaKNNELIKYFNDLKA 1007

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     471 D--TDKAN---KQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNhvIRDE---EVSSADISSSSEVISQHLVSYRN 542
Cdd:TIGR01612 1008 NlgKNKENmlyHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYN--IIDEiekEIGKNIELLNKEILEEAEINITN 1085

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     543 IEELQQQNQRL-LVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHqmqLVDSIVRQrdmyrillsqt 621
Cdd:TIGR01612 1086 FNEIKEKLKHYnFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSEN---YIDEIKAQ----------- 1151

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     622 tgvaiplhASSLDDVslastpkrpsTSQTVSTPAPVPVIESTEAIEAKAALKqlQEIFENYKKEKAENEKIQNEQ--LEK 699
Cdd:TIGR01612 1152 --------INDLEDV----------ADKAISNDDPEEIEKKIENIVTKIDKK--KNIYDEIKKLLNEIAEIEKDKtsLEE 1211

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     700 LQE-QVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQK------LTATTQKQEQIINTMTQDLR---- 768
Cdd:TIGR01612 1212 VKGiNLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEienemgIEMDIKAEMETFNISHDDDKdhhi 1291

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     769 -GANEKLAVAEIRAENLKKEK---EMLKLSEVRLSQQRESLLAEQRGQ--NLLLTNLQTIQGILERSETetkQRLSSQIE 842
Cdd:TIGR01612 1292 iSKKHDENISDIREKSLKIIEdfsEESDINDIKKELQKNLLDAQKHNSdiNLYLNEIANIYNILKLNKI---KKIIDEVK 1368

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     843 KLEHEISHLKKKLENEVEQRHTLTRNL--DVQLLDTKRQLD---------------TETNLHL-----NTKELLKNAQKE 900
Cdd:TIGR01612 1369 EYTKEIEENNKNIKDELDKSEKLIKKIkdDINLEECKSKIEstlddkdidecikkiKELKNHIlseesNIDTYFKNADEN 1448

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     901 IATLKRHLSNMEvqVASQSSQRTGKGQPSN-KEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVE-------QYQAMVTSL 972
Cdd:TIGR01612 1449 NENVLLLFKNIE--MADNKSQHILKIKKDNaTNDHDFNINELKEHIDKSKGCKDEADKNAKAIEknkelfeQYKKDVTEL 1526

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     973 eesLNKEKQVT-----EEVRKNIEVRLKESAEFQTQL-------EKKLMEVEKEKQELQDDKRRAIESmeqqlselKKTL 1040
Cdd:TIGR01612 1527 ---LNKYSALAiknkfAKTKKDSEIIIKEIKDAHKKFileaeksEQKIKEIKKEKFRIEDDAAKNDKS--------NKAA 1595

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1041 SSVQNEVqEALQRASTALSNEQQARRDCQEQA-----KIAVEAQNKYERELMLHAADVEALQ----AAKEQVSKMASVRQ 1111
Cdd:TIGR01612 1596 IDIQLSL-ENFENKFLKISDIKKKINDCLKETesiekKISSFSIDSQDTELKENGDNLNSLQefleSLKDQKKNIEDKKK 1674

                         1210
                   ....*....|.
gi 1850342    1112 HLEETTQKAES 1122
Cdd:TIGR01612 1675 ELDELDSEIEK 1685
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 123-1053 3.58e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 3.58e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     123 EKRDLIrtnERLSQELEYLTEDVKRLNEkLKESNTTKGELQLKLDElqasdvsVKYREKRLEQEKELLHSQNtwlntELK 202
Cdd:TIGR02169  154 ERRKII---DEIAGVAEFDRKKEKALEE-LEEVEENIERLDLIIDE-------KRQQLERLRREREKAERYQ-----ALL 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     203 TKTDELLalGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAH 282
Cdd:TIGR02169  218 KEKREYE--GYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEK 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     283 I-KLSNLYKSAADDSEAKSNELTRAVEELHKLLKEageankaIQDHLLEVEQSKDQMEKEMLEKIgRLEKELENANDLLS 361
Cdd:TIGR02169  296 IgELEAEIASLERSIAEKERELEDAEERLAKLEAE-------IDKLLAEIEELEREIEEERKRRD-KLTEEYAELKEELE 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     362 ATKRKgailSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLEnkrinkyLDEIVKEVEAKAPILKRQR 441
Cdd:TIGR02169  368 DLRAE----LEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQR-------LSEELADLNAAIAGIEAKI 436

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     442 EEYERAQKAVASlsvKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIrvllmeleeargnhvirdEEV 521
Cdd:TIGR02169  437 NELEEEKEDKAL---EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQREL------------------AEA 495

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     522 SSADISSSSEVISqhlvSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQ-------LKLESALTELEQLR 594
Cdd:TIGR02169  496 EAQARASEERVRG----GRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvveddAVAKEAIELLKRRK 571

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     595 KSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLhasslddvsLASTPK-RPSTSQTVSTPAPVPVIESTEAIEAKAALK 673
Cdd:TIGR02169  572 AGRATFLPLNKMRDERRDLSILSEDGVIGFAVDL---------VEFDPKyEPAFKYVFGDTLVVEDIEAARRLMGKYRMV 642

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     674 QLQ-EIFE---------NYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLH 743
Cdd:TIGR02169  643 TLEgELFEksgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     744 ERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQnllltNLQTIQ 823
Cdd:TIGR02169  723 KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS-----RIPEIQ 797

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     824 GILERSEtETKQRLSSQIEKLEHEIshlkKKLENEVEQRHTLTRNLDVQLLDTKRQLDTEtnlhlntKELLKNAQKEIAT 903
Cdd:TIGR02169  798 AELSKLE-EEVSRIEARLREIEQKL----NRLTLEKEYLEKEIQELQEQRIDLKEQIKSI-------EKEIENLNGKKEE 865

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     904 LKRHLSNMEVQVASQSSQRTGKgqpsnKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLnkeKQVT 983
Cdd:TIGR02169  866 LEEELEELEAALRDLESRLGDL-----KKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL---SEIE 937

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1850342     984 EEVRKNIEVRLKESAEfqTQLEKKLMEVEKEKQELQDDKRRAI---ESMEQQLSELKKTLSSVQNEVQEALQR 1053
Cdd:TIGR02169  938 DPKGEDEEIPEEELSL--EDVQAELQRVEEEIRALEPVNMLAIqeyEEVLKRLDELKEKRAKLEEERKAILER 1008
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1187-1638 3.83e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.39  E-value: 3.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1187 SEEGKSQEQILEILRFIRREKEIAEtRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKT 1266
Cdd:PRK03918  214 SELPELREELEKLEKEVKELEELKE-EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKA 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1267 ETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLE---------EDVKRWKA 1337
Cdd:PRK03918  293 EEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEeleerhelyEEAKAKKE 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1338 RNQHLVSQQKDPDTEEYRKLLSE----KEVHTKRIQQLTEEIGRLKAEIARSNASLT-------------------NNQN 1394
Cdd:PRK03918  373 ELERLKKRLTGLTPEKLEKELEElekaKEEIEEEISKITARIGELKKEIKELKKAIEelkkakgkcpvcgrelteeHRKE 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1395 LIQSLKEDLNKVRTEKETIqKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVmetsaqSSGDHQEQHVSVQ 1474
Cdd:PRK03918  453 LLEEYTAELKRIEKELKEI-EEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKL------KKYNLEELEKKAE 525

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1475 EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEqtvqLQSELSRLRQDLQDRT-TQEEQLRQQITEKEEKT 1553
Cdd:PRK03918  526 EYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDE----LEEELAELLKELEELGfESVEELEERLKELEPFY 601

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1554 RKAIvaakskiaHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSqYEGRISRLERELREhqERHLEQRDEPQE 1633
Cdd:PRK03918  602 NEYL--------ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE-LRKELEELEKKYSE--EEYEELREEYLE 670


                  ....*
gi 1850342   1634 PSNKV 1638
Cdd:PRK03918  671 LSREL 675
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 872-1556 1.18e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 60.75  E-value: 1.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     872 QLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQPSNKE--DVDDLVSQLRQTEEQVN 949
Cdd:TIGR00618  167 ELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKElkHLREALQQTQQSHAYLT 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     950 DLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVtEEVRKNIE-----VRLKESAEFQTQLEKKLMEVEKEKQELQDD--- 1021
Cdd:TIGR00618  247 QKREAQEEQLKKQQLLKQLRARIEELRAQEAVL-EETQERINrarkaAPLAAHIKAVTQIEQQAQRIHTELQSKMRSrak 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1022 ---KRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQA 1098
Cdd:TIGR00618  326 llmKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDIL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1099 AKEQVSKMAsvrQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEK--QNRL---LHDQIEKLSDKVVAS 1173
Cdd:TIGR00618  406 QREQATIDT---RTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKihLQESaqsLKEREQQLQTKEQIH 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1174 VKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQV-T 1252
Cdd:TIGR00618  483 LQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASlK 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1253 AKTMAQHEELMKKTETMNVVMETNKMLREEKERLeQDLQQMQAKVRKLELDILPLQEANAELS-EKSGMLQAEKKLLEED 1331
Cdd:TIGR00618  563 EQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRL-QDLTEKLSEAEDMLACEQHALLRKLQPEqDLQDVRLHLQQCSQEL 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1332 VKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKE 1411
Cdd:TIGR00618  642 ALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFN 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1412 TIQKDLDAKIIDIQEKVKTITQV-KKIGRRYKTQYEELK-AQQDKVMETSAQSSGDHQEQHVS----------VQEMQEL 1479
Cdd:TIGR00618  722 EIENASSSLGSDLAAREDALNQSlKELMHQARTVLKARTeAHFNNNEEVTAALQTGAELSHLAaeiqffnrlrEEDTHLL 801

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1850342    1480 KETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKA 1556
Cdd:TIGR00618  802 KTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 423-1170 1.38e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 60.52  E-value: 1.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     423 LDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSsvlerdnRRMEIQVKDLSQQIRV 502
Cdd:pfam15921  119 LQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQL-------RKMMLSHEGVLQEIRS 191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     503 LLMELEEARGNHVIRDEEVSSADISSSSEVISQhlvsyrnieelqqqnqrllvALRELgetrereeqettSSKITELQLK 582
Cdd:pfam15921  192 ILVDFEEASGKKIYEHDSMSTMHFRSLGSAISK--------------------ILREL------------DTEISYLKGR 239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     583 LESALTELEQLRKSRQHQMQLVdsIVRQRDMYRILLSQttgvaiplHASSLDDVSLASTPKRpstSQTVSTPAPVPVIES 662
Cdd:pfam15921  240 IFPVEDQLEALKSESQNKIELL--LQQHQDRIEQLISE--------HEVEITGLTEKASSAR---SQANSIQSQLEIIQE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     663 TEAIEAKAALKQLQEI---FENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEgyrREI 739
Cdd:pfam15921  307 QARNQNSMYMRQLSDLestVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQ---KLL 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     740 TSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNL 819
Cdd:pfam15921  384 ADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKV 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     820 QTIQGILErsetETKQRLSSQIEKL----------EHEISHLKKKLENevEQRHTLTRNLDVQLLDTKRQLDTETNLHL- 888
Cdd:pfam15921  464 SSLTAQLE----STKEMLRKVVEELtakkmtlessERTVSDLTASLQE--KERAIEATNAEITKLRSRVDLKLQELQHLk 537

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     889 NTKELLKNAQKEIATLKRHLSNME--VQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLK-------TST 959
Cdd:pfam15921  538 NEGDHLRNVQTECEALKLQMAEKDkvIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQefkilkdKKD 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     960 SNVEQYQAMVTSLEesLNKEKQVTEEVRknievRLKESAEFQTQLEKKLMEVEKEKQELQD----------DKRRAIESM 1029
Cdd:pfam15921  618 AKIRELEARVSDLE--LEKVKLVNAGSE-----RLRAVKDIKQERDQLLNEVKTSRNELNSlsedyevlkrNFRNKSEEM 690

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1030 EQQLSELKKTLSSVQNEVQEALQRASTALSNEQQArrdcqeqAKIAVEAQNKyerelmlhaadveaLQAAKEQVSKMASV 1109
Cdd:pfam15921  691 ETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHA-------MKVAMGMQKQ--------------ITAKRGQIDALQSK 749

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1850342    1110 RQHLEETTQKAESQllecKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKV 1170
Cdd:pfam15921  750 IQFLEEAMTNANKE----KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKV 806
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1359-1565 2.10e-08

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 58.69  E-value: 2.10e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1359 SEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEkvktitQVKKIG 1438
Cdd:COG3883   16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE------RREELG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1439 RRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSV--------QEMQELKETLNQAETKSKSLESQVENLQKTLSEKETE 1510
Cdd:COG3883   90 ERARALYRSGGSVSYLDVLLGSESFSDFLDRLSALskiadadaDLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 1850342  1511 ARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIA 1565
Cdd:COG3883  170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1368-1646 2.29e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.70  E-value: 2.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1368 IQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQK--DLDAKIIDIQ------EKVKTITQVKKIGR 1439
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqALLKEKREYEgyellkEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1440 RYKTQYEEL---KAQQDKVMETSAQSSGDHQEQHVSVQEMQElkETLNQAETKSKSLESQVENLQKTLSEKETEARNLQE 1516
Cdd:TIGR02169  245 QLASLEEELeklTEEISELEKRLEEIEQLLEELNKKIKDLGE--EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1517 QTVQLQSELSRLRQDLqdrttqeEQLRQQITEKeektrkaivaakskiahlAGVKDQLTKENEELKQRNGALDQQKDELD 1596
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEI-------EELEREIEEE------------------RKRRDKLTEEYAELKEELEDLRAELEEVD 377

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1850342    1597 VRITALK---SQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQIT 1646
Cdd:TIGR02169  378 KEFAETRdelKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIA 430
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 53-354 3.38e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 3.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      53 QYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLK-ALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLirtn 131
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSqELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL---- 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     132 ERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEK-ELLHSQNTWLNTELKTKTDELLA 210
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     211 LgrekgNEILELKcnLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKfHNELNAHIKLSNLYK 290
Cdd:TIGR02169  827 E-----KEYLEKE--IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR-LGDLKKERDELEAQL 898

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1850342     291 SAAddsEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEK--IGRLEKELE 354
Cdd:TIGR02169  899 REL---ERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsLEDVQAELQ 961
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1344-1563 3.94e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.85  E-value: 3.94e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1344 SQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIID 1423
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1424 IQEKVKTI-TQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQK 1502
Cdd:COG4942   99 LEAQKEELaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1850342  1503 TLSEKETEARNLQEQTVQ-------LQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSK 1563
Cdd:COG4942  179 LLAELEEERAALEALKAErqkllarLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1411-1661 4.48e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 4.48e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1411 ETIQKDLDaKIIDIQEKVKTitQVKKIGRRYKtQYEELKAQQDKVMETSAQSSGDHQEQHVsvQEMQELKETLNQAETKS 1490
Cdd:TIGR02168  182 ERTRENLD-RLEDILNELER--QLKSLERQAE-KAERYKELKAELRELELALLVLRLEELR--EELEELQEELKEAEEEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1491 KSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITE-----------------KEEKT 1553
Cdd:TIGR02168  256 EELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANlerqleeleaqleelesKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1554 RKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQY----------EGRISRLERELrEHQER 1623
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVaqlelqiaslNNEIERLEARL-ERLED 414

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1850342    1624 HLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIAST 1661
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEAELKELQAELEELEEELEEL 452
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 543-1119 4.58e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 4.58e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   543 IEELQQQNQRLLVALREL--GETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQ 620
Cdd:COG1196  248 LEELEAELEELEAELAELeaELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   621 TTGVAIplhasslddvslastpkrpstsqtvstpapvpvIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKL 700
Cdd:COG1196  328 LEEELE---------------------------------ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   701 QEQVTDLRSQNtkiSTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRganEKLAVAEIR 780
Cdd:COG1196  375 AEAEEELEELA---EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE---EEEALEEAA 448

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   781 AENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQtiqgilERSETETKQRLSSQIEKLEHEISHLKKKLENEVE 860
Cdd:COG1196  449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE------AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   861 QRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQ 940
Cdd:COG1196  523 AGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD 602

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   941 LRQTEEQVNDLKERLktstsnVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD 1020
Cdd:COG1196  603 LVASDLREADARYYV------LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1021 DKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAK 1100
Cdd:COG1196  677 AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756

                        570
                 ....*....|....*....
gi 1850342  1101 EQVSKMASVRQHLEETTQK 1119
Cdd:COG1196  757 PEPPDLEELERELERLERE 775
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 680-1436 4.58e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 58.49  E-value: 4.58e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     680 ENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQI 759
Cdd:TIGR04523   60 DKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKN 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     760 INTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQrLSS 839
Cdd:TIGR04523  140 IDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKS-LES 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     840 QIEKLEHEishlKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQS 919
Cdd:TIGR04523  219 QISELKKQ----NNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     920 SQrtgkgqpsnkedvddlVSQLRQTEEQV--NDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKES 997
Cdd:TIGR04523  295 SE----------------ISDLNNQKEQDwnKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESEN 358

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     998 AEFQTQLEKKLMEVEKEKQElQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDcQEQAKIAVE 1077
Cdd:TIGR04523  359 SEKQRELEEKQNEIEKLKKE-NQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE-IERLKETII 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1078 AQNKYERELmlhaadVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCvcrcEDLEKQNR 1157
Cdd:TIGR04523  437 KNNSEIKDL------TNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKEL----KKLNEEKK 506

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1158 LLHDQIEKLSDKVvasvkegvqgplnvslsEEGKSQEQILEilrfirreKEIAETRFEVAQVESlryrqrvellerelqe 1237
Cdd:TIGR04523  507 ELEEKVKDLTKKI-----------------SSLKEKIEKLE--------SEKKEKESKISDLED---------------- 545

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1238 lqdslnaerekvqvtaktmaqheELMKKTETMNvvmetnkmlreeKERLEQDLQQMQAKVRKLELDILPLQEANAELSEK 1317
Cdd:TIGR04523  546 -----------------------ELNKDDFELK------------KENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQEL 590

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1318 SGMLQAEKKlleedvkrwkarnqhlvsqqkdpdteeyrKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQ 1397
Cdd:TIGR04523  591 IDQKEKEKK-----------------------------DLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKN 641

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1850342    1398 SLKEDLNKVRTE-KETIQK--DLDAKIIDIQEKVKTITQVKK 1436
Cdd:TIGR04523  642 KLKQEVKQIKETiKEIRNKwpEIIKKIKESKTKIDDIIELMK 683
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 992-1628 6.41e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 58.44  E-value: 6.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     992 VRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTAlsneQQARRDCQE- 1070
Cdd:TIGR00618  197 ELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLL----KQLRARIEEl 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1071 QAKIAVEAQNKYERELMLHAADVEALQAAKEQVskmasvRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRce 1150
Cdd:TIGR00618  273 RAQEAVLEETQERINRARKAAPLAAHIKAVTQI------EQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQR-- 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1151 DLEKQNRLLHDQIEKLSDKVVASVKEGVQgplNVSLSEEGKSQEQILEILRFIRR--EKEIAETRFEVAQVESLRYRQRV 1228
Cdd:TIGR00618  345 RLLQTLHSQEIHIRDAHEVATSIREISCQ---QHTLTQHIHTLQQQKTTLTQKLQslCKELDILQREQATIDTRTSAFRD 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1229 ELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTEtmnvVMETNKMLREEKERLE--QDLQQMQAKVRKLELDILP 1306
Cdd:TIGR00618  422 LQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIH----LQESAQSLKEREQQLQtkEQIHLQETRKKAVVLARLL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1307 LQEANAELSEKSgmlqaekkLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSN 1386
Cdd:TIGR00618  498 ELQEEPCPLCGS--------CIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQ 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1387 ASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKI---------IDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVME 1457
Cdd:TIGR00618  570 QSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSeaedmlaceQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALH 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1458 TSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENL----------QKTLSEKETEARNLQEQTVQLQSELSR 1527
Cdd:TIGR00618  650 ALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLtywkemlaqcQTLLRELETHIEEYDREFNEIENASSS 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1528 LRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYE 1607
Cdd:TIGR00618  730 LGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIG 809

                          650       660
                   ....*....|....*....|.
gi 1850342    1608 GRISRLERELREHQERHLEQR 1628
Cdd:TIGR00618  810 QEIPSDEDILNLQCETLVQEE 830
mukB PRK04863
chromosome partition protein MukB;
994-1633 7.20e-08

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 58.43  E-value: 7.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    994 LKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIE------SMEQQLSELKKTLSSVQNEV--QEALQRASTALsNEQQAR 1065
Cdd:PRK04863  285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAElneaesDLEQDYQAASDHLNLVQTALrqQEKIERYQADL-EELEER 363

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1066 rdcQEQAKIAVEAQNkyERELMLHAADVEALQAAKEQVSKMASVRQHLEETtQKAESQLLECKASWEErermlkdevSKC 1145
Cdd:PRK04863  364 ---LEEQNEVVEEAD--EQQEENEARAEAAEEEVDELKSQLADYQQALDVQ-QTRAIQYQQAVQALER---------AKQ 428

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1146 VCRCEDLEKQNrlLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQ-EQILEILR--------------FIRREKEIA 1210
Cdd:PRK04863  429 LCGLPDLTADN--AEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQfEQAYQLVRkiagevsrseawdvARELLRRLR 506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1211 ETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKV---QVTAKTMAQ--HEELMKKTETMNVVMETnkmLREEKER 1285
Cdd:PRK04863  507 EQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRlgkNLDDEDELEqlQEELEARLESLSESVSE---ARERRMA 583

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1286 LEQDLQQMQAKVRKLE---LDILPLQEANAELSEKSG--------MLQAEKKLLEEDVKRWKARNQhlVSQQKDPDTEEY 1354
Cdd:PRK04863  584 LRQQLEQLQARIQRLAaraPAWLAAQDALARLREQSGeefedsqdVTEYMQQLLERERELTVERDE--LAARKQALDEEI 661

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1355 RKLLSEKEVHTKRIQQLTEEI-GRLKAEI------------------ARsNASLTNNQNLIQS-------LKEDLNKV-- 1406
Cdd:PRK04863  662 ERLSQPGGSEDPRLNALAERFgGVLLSEIyddvsledapyfsalygpAR-HAIVVPDLSDAAEqlagledCPEDLYLIeg 740

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1407 --------RTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQY-EELKAQQDKVMETSAQSSGDhqeqhvsVQEMQ 1477
Cdd:PRK04863  741 dpdsfddsVFSVEELEKAVVVKIADRQWRYSRFPEVPLFGRAAREKRiEQLRAEREELAERYATLSFD-------VQKLQ 813

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1478 ELKETLNQAETKSKSL------ESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQ-------------DRTTQ 1538
Cdd:PRK04863  814 RLHQAFSRFIGSHLAVafeadpEAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSalnrllprlnllaDETLA 893

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1539 E--EQLRQQITEKEEKTR--KAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKS--------QY 1606
Cdd:PRK04863  894 DrvEEIREQLDEAEEAKRfvQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEvvqrrahfSY 973

                         730       740       750
                  ....*....|....*....|....*....|...
gi 1850342   1607 EGRISRLERE------LREHQERHLEQRDEPQE 1633
Cdd:PRK04863  974 EDAAEMLAKNsdlnekLRQRLEQAEQERTRARE 1006
PTZ00121 PTZ00121
MAEBL; Provisional
 117-612 7.73e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.23  E-value: 7.73e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    117 KEELEAEKRDLIRTNERLSQELEYLTEDVKRLN------EKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELL 190
Cdd:PTZ00121 1237 KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQaaikaeEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKK 1316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    191 HSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQAS 270
Cdd:PTZ00121 1317 ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    271 MEEKFHNELNA-HIKLSNLYKSAADDSEAKSNELTRAvEELHKLLKE---AGEANKAIQDHLLEVEQSKDQMEKEMLEKI 346
Cdd:PTZ00121 1397 KKKAEEDKKKAdELKKAAAAKKKADEAKKKAEEKKKA-DEAKKKAEEakkADEAKKKAEEAKKAEEAKKKAEEAKKADEA 1475

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    347 GRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYvETQDQLLLEKLENKRinkYLDEI 426
Cdd:PTZ00121 1476 KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE-EAKKADEAKKAEEKK---KADEL 1551

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    427 VKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLME 506
Cdd:PTZ00121 1552 KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE 1631

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    507 LEEARGNHVIRDEEVSSADISSSSEviSQHLVSYRNIEELQQQNQRLLVALR-----ELGETREREEQETTSSKITELQL 581
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAE--EENKIKAAEEAKKAEEDKKKAEEAKkaeedEKKAAEALKKEAEEAKKAEELKK 1709

                         490       500       510
                  ....*....|....*....|....*....|.
gi 1850342    582 KLESALTELEQLRKSRQHQMQLVDSIVRQRD 612
Cdd:PTZ00121 1710 KEAEEKKKAEELKKAEEENKIKAEEAKKEAE 1740
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 667-1046 1.06e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.34  E-value: 1.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     667 EAKAALKQLQEIFENYKKEKAENEKI---QNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLH 743
Cdd:TIGR04523  311 ELKSELKNQEKKLEEIQNQISQNNKIisqLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLE 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     744 ERNQKLTATTQKQEQIintmtqdlrgaNEKLavaEIRAENLKKEKEMLklsevrlsqqresllaEQRGQNLLLTNLQtiq 823
Cdd:TIGR04523  391 SQINDLESKIQNQEKL-----------NQQK---DEQIKKLQQEKELL----------------EKEIERLKETIIK--- 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     824 gilersetetkqrLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRqldTETNLHLNTKElLKNAQKEIAT 903
Cdd:TIGR04523  438 -------------NNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINK---IKQNLEQKQKE-LKSKEKELKK 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     904 LKRHLSNMEVQVASQSSQrtgkgQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQamvtsLEESLNKEKQVT 983
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKK-----ISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKEN-----LEKEIDEKNKEI 570

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1850342     984 EEVRKNIEVRLKEsaefQTQLEKKLMEVEKEKQELqddkRRAIESMEQQLSELKKTLSSVQNE 1046
Cdd:TIGR04523  571 EELKQTQKSLKKK----QEEKQELIDQKEKEKKDL----IKEIEEKEKKISSLEKELEKAKKE 625
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1421-1620 1.23e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1421 IIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDkvMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENL 1500
Cdd:COG4913  244 LEDAREQIELLEPIRELAERYAAARERLAELEY--LRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDAL 321

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1501 QKTLSEKETEARN--------LQEQTVQLQSELSRLRqdlQDRTTQEEQLRqQITEKEEKTRKAIVAAKSKIAHLAGVKD 1572
Cdd:COG4913  322 REELDELEAQIRGnggdrleqLEREIERLERELEERE---RRRARLEALLA-ALGLPLPASAEEFAALRAEAAALLEALE 397

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 1850342  1573 QLTKENE----ELKQRNGALDQQKDELDVRITAL---KSQYEGRISRLERELREH 1620
Cdd:COG4913  398 EELEALEealaEAEAALRDLRRELRELEAEIASLerrKSNIPARLLALRDALAEA 452
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1052-1619 1.35e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.36  E-value: 1.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1052 QRASTALSNEQQARRDCQEQ-AKIAVEAQNKYERELmlhaadVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKAS 1130
Cdd:PRK02224  169 ERASDARLGVERVLSDQRGSlDQLKAQIEEKEEKDL------HERLNGLESELAELDEEIERYEEQREQARETRDEADEV 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1131 WEERERmlkdevskcvcRCEDLEKqnrlLHDQIEKLSDKVVASVKEgvqgplNVSLSEEGKSQEQILEILRfIRREKEIA 1210
Cdd:PRK02224  243 LEEHEE-----------RREELET----LEAEIEDLRETIAETERE------REELAEEVRDLRERLEELE-EERDDLLA 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1211 ETRFEVAQVESLRyrQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTEtmnvvmETNKMLREEKERLEQDL 1290
Cdd:PRK02224  301 EAGLDDADAEAVE--ARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE------ERAEELREEAAELESEL 372

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1291 QQMQAKVRKLELDILPLQEANAELSEK-------SGMLQAEKKLLEEDVKRWKARNQHLVS--QQKDPDTEEYRKLLSEK 1361
Cdd:PRK02224  373 EEAREAVEDRREEIEELEEEIEELRERfgdapvdLGNAEDFLEELREERDELREREAELEAtlRTARERVEEAEALLEAG 452

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1362 EVHT------------------KRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEdLNKVRTEKETIQKDLDAKIID 1423
Cdd:PRK02224  453 KCPEcgqpvegsphvetieedrERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDR-IERLEERREDLEELIAERRET 531

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1424 IQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSgdhQEQHVSVQEMQELKETLNQAETKSKSL------ESQV 1497
Cdd:PRK02224  532 IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAR---EEVAELNSKLAELKERIESLERIRTLLaaiadaEDEI 608

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1498 ENLQ---KTLSEKETEARN----LQEQTVQLQSEL--SRLRQDLQDRTTQEEQLRQ------QITEKEEKTRKAIVAAKS 1562
Cdd:PRK02224  609 ERLRekrEALAELNDERRErlaeKRERKRELEAEFdeARIEEAREDKERAEEYLEQveekldELREERDDLQAEIGAVEN 688

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1850342   1563 KIAHLAGVKDQLtKENEELKQRNGALDQQKDELDVRITALKSQYEGR-ISRLERELRE 1619
Cdd:PRK02224  689 ELEELEELRERR-EALENRVEALEALYDEAEELESMYGDLRAELRQRnVETLERMLNE 745
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
671-1220 1.64e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.00  E-value: 1.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    671 ALKQLQEIFENYKKEKAENEKIQnEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLT 750
Cdd:PRK03918  163 AYKNLGEVIKEIKRRIERLEKFI-KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    751 AT---TQKQEQIINTMTQDLRGANEKLAVAEIRAENLK-KEKEMLKLSE-----VRLSQQRESLLAEQRGQNLLLTNL-Q 820
Cdd:PRK03918  242 ELekeLESLEGSKRKLEEKIRELEERIEELKKEIEELEeKVKELKELKEkaeeyIKLSEFYEEYLDELREIEKRLSRLeE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    821 TIQGILER-SETETKqrlSSQIEKLEHEISHLKKKLEnEVEQRHTL---TRNLDVQLLDTKRQLDTETNLHLNTK-ELLK 895
Cdd:PRK03918  322 EINGIEERiKELEEK---EERLEELKKKLKELEKRLE-ELEERHELyeeAKAKKEELERLKKRLTGLTPEKLEKElEELE 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    896 NAQKEIATLKRHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEES 975
Cdd:PRK03918  398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    976 LNKEKQVTEEVRKNIE--VRLKESAEFQTQLEKKLMEVEKEKQElqdDKRRAIESMEQQLSELKKTLSSVQNEVQ--EAL 1051
Cdd:PRK03918  478 LRKELRELEKVLKKESelIKLKELAEQLKELEEKLKKYNLEELE---KKAEEYEKLKEKLIKLKGEIKSLKKELEklEEL 554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1052 QRASTALSNE-QQARRDCQEQAKIAVEAQNKYERELmlhAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKAS 1130
Cdd:PRK03918  555 KKKLAELEKKlDELEEELAELLKELEELGFESVEEL---EERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKA 631

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1131 WEERERMLKDeVSKCVCRCEDLEKqnRLLHDQIEKLSDKVVASVKEgvQGPLNVSLSEEGKSQEQILEILRFIRREK-EI 1209
Cdd:PRK03918  632 FEELAETEKR-LEELRKELEELEK--KYSEEEYEELREEYLELSRE--LAGLRAELEELEKRREEIKKTLEKLKEELeER 706

                         570
                  ....*....|.
gi 1850342   1210 AETRFEVAQVE 1220
Cdd:PRK03918  707 EKAKKELEKLE 717
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 575-1513 1.72e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.00  E-value: 1.72e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     575 KITELQLKLESALTELEQLRKSRQHQMQlvdsivrqrdmYRILLSQTTGVAIPLHASSLddvslastpkrpstsqtvstp 654
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAER-----------YQALLKEKREYEGYELLKEK--------------------- 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     655 apvpviesteaieaKAALKQLQEIfenyKKEKAENEkiqnEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNveg 734
Cdd:TIGR02169  233 --------------EALERQKEAI----ERQLASLE----EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE--- 287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     735 yrrEITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNL 814
Cdd:TIGR02169  288 ---EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE 364

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     815 LLTNLQTIQGILERSETETKQRLSSqiekleheishLKKKLENEVEQRHTLTRNLDvQLLDTKRQLDTETnlhLNTKELL 894
Cdd:TIGR02169  365 ELEDLRAELEEVDKEFAETRDELKD-----------YREKLEKLKREINELKRELD-RLQEELQRLSEEL---ADLNAAI 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     895 KNAQKEIATLKRHLSNMEVQVASQSSQRTgkgqpSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEE 974
Cdd:TIGR02169  430 AGIEAKINELEEEKEDKALEIKKQEWKLE-----QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     975 SLNKEKQVTEEVRKNIE---------VRLKEsaEFQTQLEK------KLMEVEKEkqelqDDKRRAIESMEqqlselkkt 1039
Cdd:TIGR02169  505 RVRGGRAVEEVLKASIQgvhgtvaqlGSVGE--RYATAIEVaagnrlNNVVVEDD-----AVAKEAIELLK--------- 568

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1040 lssvqnevQEALQRAS-TALSNEQQARRD--------CQEQAKIAVEAQNKYERELMLHAAD---VEALQAAKEQVSK-- 1105
Cdd:TIGR02169  569 --------RRKAGRATfLPLNKMRDERRDlsilsedgVIGFAVDLVEFDPKYEPAFKYVFGDtlvVEDIEAARRLMGKyr 640

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1106 MASVRQHLEETT------QKAESQLLECKASWEERERMLKDEVskcvcrcEDLEKQ-NRLLHDQ--IEKLSDKVVASVKE 1176
Cdd:TIGR02169  641 MVTLEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERL-------EGLKRElSSLQSELrrIENRLDELSQELSD 713

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1177 GVQgplnvSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQvTAKTM 1256
Cdd:TIGR02169  714 ASR-----KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALN-DLEAR 787

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1257 AQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVkrwk 1336
Cdd:TIGR02169  788 LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKK---- 863

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1337 arnqhlvsqqkdpdteeyRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKvrteKETIQKD 1416
Cdd:TIGR02169  864 ------------------EELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEK----KRKRLSE 921

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1417 LDAKIIDIQEKVKTITQVKKIGRRYKTQ---YEELKAQQDKvMETSAQSSGDhqEQHVSVQEMQELKETLNQAETKSKSL 1493
Cdd:TIGR02169  922 LKAKLEALEEELSEIEDPKGEDEEIPEEelsLEDVQAELQR-VEEEIRALEP--VNMLAIQEYEEVLKRLDELKEKRAKL 998

                          970       980
                   ....*....|....*....|
gi 1850342    1494 ESQVENLQKTLSEKETEARN 1513
Cdd:TIGR02169  999 EEERKAILERIEEYEKKKRE 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 423-1036 1.84e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   423 LDEIVKEVEAKAPILKRQREEYERAQ--------KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVK 494
Cdd:COG1196  191 LEDILGELERQLEPLERQAEKAERYRelkeelkeLEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELE 270

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   495 DLSQQIRVLLMELEEARGNHVIRDEEVSSADissssevisqhlvsyRNIEELQQQNQRLLVALRELGETrereeqettss 574
Cdd:COG1196  271 ELRLELEELELELEEAQAEEYELLAELARLE---------------QDIARLEERRRELEERLEELEEE----------- 324

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   575 kITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTvstp 654
Cdd:COG1196  325 -LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA---- 399

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   655 apvpvIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEG 734
Cdd:COG1196  400 -----AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   735 YRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIR------AENLKKEKEMLKLSEVRLS-----QQRE 803
Cdd:COG1196  475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglagavAVLIGVEAAYEAALEAALAaalqnIVVE 554

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   804 SLLAEQRGQNLLLTNLQTIQGILErsetETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTE 883
Cdd:COG1196  555 DDEVAAAAIEYLKAAKAGRATFLP----LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA 630

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   884 TNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVE 963
Cdd:COG1196  631 RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA 710

                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1850342   964 QYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQddkrRAIESMEQQLSEL 1036
Cdd:COG1196  711 EAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE----RELERLEREIEAL 779
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1474-1623 3.01e-07

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 53.78  E-value: 3.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1474 QEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLR--QDLQDRTTQEEQLRQQITEKEE 1551
Cdd:COG1579   31 AELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRnnKEYEALQKEIESLKRRISDLED 110

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1850342  1552 KTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQER 1623
Cdd:COG1579  111 EILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPELLALYER 182
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 666-1621 3.38e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 55.95  E-value: 3.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     666 IEAKAALKQLQEIFENYKKEKAENEKIQNEQ------LEKLQEQVTDLRSQNTKI--------------STQLDFASKRY 725
Cdd:pfam01576   96 NEKKKMQQHIQDLEEQLDEEEAARQKLQLEKvtteakIKKLEEDILLLEDQNSKLskerklleerisefTSNLAEEEEKA 175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     726 EMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLA-----VAEIRAENLKKEKEmlklsevrlsq 800
Cdd:pfam01576  176 KSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAelqaqIAELRAQLAKKEEE----------- 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     801 qresllaeqrgqnllltnlqtIQGILERSETETKQRLSSQ--IEKLEHEISHLKKKLENEVEQRHTLT---RNLDVQLLD 875
Cdd:pfam01576  245 ---------------------LQAALARLEEETAQKNNALkkIRELEAQISELQEDLESERAARNKAEkqrRDLGEELEA 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     876 TKRQLDTETNLHLNTKELLKNAQKEIATLKRHLS----NMEVQVASQSSQRTgkgqpsnkEDVDDLVSQLrqteEQVNDL 951
Cdd:pfam01576  304 LKTELEDTLDTTAAQQELRSKREQEVTELKKALEeetrSHEAQLQEMRQKHT--------QALEELTEQL----EQAKRN 371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     952 KERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKEsaefqtqLEKKLMEVEKEKQELQDDKRR------- 1024
Cdd:pfam01576  372 KANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQE-------LQARLSESERQRAELAEKLSKlqseles 444

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1025 ---AIESMEQQLSELKKTLSSVQNE---VQEALQRA-------STALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAA 1091
Cdd:pfam01576  445 vssLLNEAEGKNIKLSKDVSSLESQlqdTQELLQEEtrqklnlSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQA 524

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1092 dveALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERmlkdevskcvcRCEDLEKQNRLLHDQIEKLsdkvv 1171
Cdd:pfam01576  525 ---QLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAA-----------AYDKLEKTKNRLQQELDDL----- 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1172 aSVKEGVQGPLNVSLSEEGKSQEQILeilrfirrekeiAETRFEVAQVESLRYRqrvellerelqelqdslnAEREKVQV 1251
Cdd:pfam01576  586 -LVDLDHQRQLVSNLEKKQKKFDQML------------AEEKAISARYAEERDR------------------AEAEAREK 634

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1252 TAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEED 1331
Cdd:pfam01576  635 ETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDA 714

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1332 VKRWKARNQHLVSQQKdpdteeyRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKE 1411
Cdd:pfam01576  715 KLRLEVNMQALKAQFE-------RDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQID 787

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1412 TIQKDLDakiidiqEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVsvqEMQELKETLNQAETKSK 1491
Cdd:pfam01576  788 AANKGRE-------EAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEA---ELLQLQEDLAASERARR 857

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1492 SLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLR---QQITEKEEKTRKAIVAAKSKIAHLA 1568
Cdd:pfam01576  858 QAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNdrlRKSTLQVEQLTTELAAERSTSQKSE 937

                          970       980       990      1000      1010
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1850342    1569 GVKDQLTKENEELKQRNGALDQQ-KDELDVRITALKSQYEGRISRLERELREHQ 1621
Cdd:pfam01576  938 SARQQLERQNKELKAKLQEMEGTvKSKFKSSIAALEAKIAQLEEQLEQESRERQ 991
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 816-1529 3.61e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 56.00  E-value: 3.61e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     816 LTNLQTIQGIL-ERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNlhlNTKELL 894
Cdd:pfam12128  227 IRDIQAIAGIMkIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDD---QWKEKR 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     895 KNAQKEIATLKRHLSNMEVQVASQSSQRtGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKtstsnveqyqamvtSLEE 974
Cdd:pfam12128  304 DELNGELSAADAAVAKDRSELEALEDQH-GAFLDADIETAAADQEQLPSWQSELENLEERLK--------------ALTG 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     975 SLNKEKQVTEEVRKNIEVRLK-ESAEFQTQLEKKLMEVEKEKQELQDDkrraiesMEQQLSELKKTLSSVQNEVQEALQR 1053
Cdd:pfam12128  369 KHQDVTAKYNRRRSKIKEQNNrDIAGIKDKLAKIREARDRQLAVAEDD-------LQALESELREQLEAGKLEFNEEEYR 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1054 ASTALSNEQ------QARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMasvRQHLEETTQKAESQLLEC 1127
Cdd:pfam12128  442 LKSRLGELKlrlnqaTATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKR---RDQASEALRQASRRLEER 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1128 KASWEERERMLKDEVSKCVcrcEDLEKQNRLLHDQIEKlsdkvVASVKEGVQGPLNVSLSEEGKSQEQILEILrfirrek 1207
Cdd:pfam12128  519 QSALDELELQLFPQAGTLL---HFLRKEAPDWEQSIGK-----VISPELLHRTDLDPEVWDGSVGGELNLYGV------- 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1208 eiaetRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQ-HEELMKKTETMNVVMETNKMLREEKERL 1286
Cdd:pfam12128  584 -----KLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQaNGELEKASREETFARTALKNARLDLRRL 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1287 EQDLQQMQAKVRKleldilPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVhtk 1366
Cdd:pfam12128  659 FDEKQSEKDKKNK------ALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDA--- 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1367 riqqlteEIGRLKAEIARSNASLTNNQNLIQS-LKEDLNKVRTEKETIQKdLDAKIIDIQEKVKTITQVKKIGRRYKTQY 1445
Cdd:pfam12128  730 -------QLALLKAAIAARRSGAKAELKALETwYKRDLASLGVDPDVIAK-LKREIRTLERKIERIAVRRQEVLRYFDWY 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1446 eelkaqqdkvmetsaqssgdhqeQHVSVQEMQELKETLNQAETKSKSLESQVENLQKT----LSEKETEARNLQEQTVQL 1521
Cdd:pfam12128  802 -----------------------QETWLQRRPRLATQLSNIERAISELQQQLARLIADtklrRAKLEMERKASEKQQVRL 858


                   ....*...
gi 1850342    1522 QSELSRLR 1529
Cdd:pfam12128  859 SENLRGLR 866
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 814-1057 3.98e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 3.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   814 LLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRhtltRNLDVQLLDTKRQL-DTETNLHLNTKE 892
Cdd:COG4942    9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL----AALERRIAALARRIrALEQELAALEAE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   893 lLKNAQKEIATLKRHLSNMEVQVASQ--SSQRTGKGQPS----NKEDVDDLVSQLRQTEEQVNDLKERLKTstsnVEQYQ 966
Cdd:COG4942   85 -LAELEKEIAELRAELEAQKEELAELlrALYRLGRQPPLalllSPEDFLDAVRRLQYLKYLAPARREQAEE----LRADL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   967 AMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQddkrRAIESMEQQLSELKKTLSSVQNE 1046
Cdd:COG4942  160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELA----AELAELQQEAEELEALIARLEAE 235

                        250
                 ....*....|.
gi 1850342  1047 VQEALQRASTA 1057
Cdd:COG4942  236 AAAAAERTPAA 246
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 25-273 4.47e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 4.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      25 LEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLvneTRECQSLRLELEKLNNQLKaltEKNKELEIAQD 104
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRV---KEKIGELEAEIASLERSIA---EKERELEDAEE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     105 RNIAIQSQFTRTKEE-------LEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGEL---QLKLDELQASDV 174
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEieelereIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELkdyREKLEKLKREIN 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     175 SVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALG---REKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQ 251
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEeekEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE 482

                          250       260
                   ....*....|....*....|..
gi 1850342     252 KHVEDLLTKLKEAKEQQASMEE 273
Cdd:TIGR02169  483 KELSKLQRELAEAEAQARASEE 504
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1365-1601 5.74e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.38  E-value: 5.74e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1365 TKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQ 1444
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1445 YEELKAQQDKVMETSAQSSGDHQEQHVSVQEmqelkeTLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSE 1524
Cdd:COG4942   99 LEAQKEELAELLRALYRLGRQPPLALLLSPE------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1850342  1525 LSRLRQDLQDRTTQEEQLRQQITEKEektrKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITA 1601
Cdd:COG4942  173 RAELEALLAELEEERAALEALKAERQ----KLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 13-352 5.75e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 5.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      13 ELNKLpKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQqyfeIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKAL 92
Cdd:TIGR02169  689 ELSSL-QSELRRIENRLDELSQELSDASRKIGEIEKEIEQ----LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKEL 763

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      93 TEKNKELEiaqdrniaiqSQFTRTKEELEAEKRDL----IRTNERLSQEL-EYLTEDVKRLNE---KLKESNTTKGELQL 164
Cdd:TIGR02169  764 EARIEELE----------EDLHKLEEALNDLEARLshsrIPEIQAELSKLeEEVSRIEARLREieqKLNRLTLEKEYLEK 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     165 KLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNeileLKCNLENKKEEVSRLEEQMNGLK 244
Cdd:TIGR02169  834 EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGD----LKKERDELEAQLRELERKIEELE 909

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     245 TSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLyksaaDDSEAKSNELTRAVEELHKLLKEAGEANKAI 324
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL-----EDVQAELQRVEEEIRALEPVNMLAIQEYEEV 984

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1850342     325 QDHLLEVEQSKDQMEKE---MLEKIGRLEKE 352
Cdd:TIGR02169  985 LKRLDELKEKRAKLEEErkaILERIEEYEKK 1015
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1368-1644 8.20e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 8.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1368 IQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEE 1447
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSN 205

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1448 LKAQqdkvmetsaqssgdhqeqhvsVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSR 1527
Cdd:TIGR04523  206 LKKK---------------------IQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNK 264

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1528 LRQDLQDRTTQEEQLRQQITEKEEKTRKaivaAKSKIAHLAGVKDQ-LTKE-NEELKQRNGALDQQKDELDvRITALKSQ 1605
Cdd:TIGR04523  265 IKKQLSEKQKELEQNNKKIKELEKQLNQ----LKSEISDLNNQKEQdWNKElKSELKNQEKKLEEIQNQIS-QNNKIISQ 339

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1850342    1606 YEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQ 1644
Cdd:TIGR04523  340 LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE 378
PTZ00121 PTZ00121
MAEBL; Provisional
 278-1119 1.67e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.99  E-value: 1.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    278 ELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMekemlekigrleKELENAN 357
Cdd:PTZ00121 1061 EAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAK------------KKAEDAR 1128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    358 DLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRInkylDEIVKEVEAKAPIL 437
Cdd:PTZ00121 1129 KAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKA----EELRKAEDARKAEA 1204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    438 KRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEAR-GNHVI 516
Cdd:PTZ00121 1205 ARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARkADELK 1284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    517 RDEEVSSADISSSSEVIsqhlvsyRNIEELQQQNQrllvalrelgetrereeqetTSSKITELQLKLESALTELEQLRKS 596
Cdd:PTZ00121 1285 KAEEKKKADEAKKAEEK-------KKADEAKKKAE--------------------EAKKADEAKKKAEEAKKKADAAKKK 1337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    597 RQHqmqlvdsivrqrdmyrillsqttgvaiplhASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQ 676
Cdd:PTZ00121 1338 AEE------------------------------AKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA 1387

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    677 EIFENYK--KEKAENEKIQNEQLEKLQE--QVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTAT 752
Cdd:PTZ00121 1388 EEKKKADeaKKKAEEDKKKADELKKAAAakKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE 1467

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    753 TQKQEQIINTMTQDLRGANEklavAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQnllltnlqtiqgiLERSETE 832
Cdd:PTZ00121 1468 EAKKADEAKKKAEEAKKADE----AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK-------------ADEAKKA 1530

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    833 TKQRLSSQIEKLEheishlKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKeiatlkrhlSNME 912
Cdd:PTZ00121 1531 EEAKKADEAKKAE------EKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE---------ARIE 1595

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    913 VQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNvEQYQAMVTSLEESLNKEKQVTEEVRKNIEV 992
Cdd:PTZ00121 1596 EVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE-EKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    993 RLKESAEFQTQLEKKLMEVEKEKQElqddKRRAIESMEQQLSELKKTLSSVQNEVQEALQRAstalsneQQARRDCQEQA 1072
Cdd:PTZ00121 1675 KKAEEAKKAEEDEKKAAEALKKEAE----EAKKAEELKKKEAEEKKKAEELKKAEEENKIKA-------EEAKKEAEEDK 1743

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....*...
gi 1850342   1073 KIAVEAQ-NKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQK 1119
Cdd:PTZ00121 1744 KKAEEAKkDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEK 1791
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1401-1591 2.03e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 2.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1401 EDLNKVRTEKETIQKDLDAkiIDIQEKVKTITQVKKIGRRY---KTQYEELKAQQDKVMETSAQSSGDHQEQHvsvQEMQ 1477
Cdd:COG4913  252 ELLEPIRELAERYAAARER--LAELEYLRAALRLWFAQRRLellEAELEELRAELARLEAELERLEARLDALR---EELD 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1478 ELKETLNQAETKSK-SLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKA 1556
Cdd:COG4913  327 ELEAQIRGNGGDRLeQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEA 406

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 1850342  1557 IVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQ 1591
Cdd:COG4913  407 LAEAEAALRDLRRELRELEAEIASLERRKSNIPAR 441
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 780-1621 2.13e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 53.26  E-value: 2.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     780 RAENLKKEKEMLKLSEVRLS--QQRESLLAEQRgqNLLLTNLQTIQGILERSEtETKQRLSSQIEKLEHEISHLKKKLEN 857
Cdd:pfam01576   10 KEEELQKVKERQQKAESELKelEKKHQQLCEEK--NALQEQLQAETELCAEAE-EMRARLAARKQELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     858 EVE---QRHTLTRNLDVQLLDTKRQLDTETNLHlntkellKNAQKEIATLKRHLSNMEVQVASQSSQRT--GKGQPSNKE 932
Cdd:pfam01576   87 EEErsqQLQNEKKKMQQHIQDLEEQLDEEEAAR-------QKLQLEKVTTEAKIKKLEEDILLLEDQNSklSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     933 DVDDLVSQLRQTEEQVNDLkERLKTstsnveQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKES-------AEFQTQLE 1005
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSL-SKLKN------KHEAMISDLEERLKKEEKGRQELEKAKRKLEGEStdlqeqiAELQAQIA 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1006 KKLMEVEKEKQELQDDKRRAIESMEQQLSELKKT--LSSVQNEVQEALQRASTALSNEQQARRDCQEQ------------ 1071
Cdd:pfam01576  233 ELRAQLAKKEEELQAALARLEEETAQKNNALKKIreLEAQISELQEDLESERAARNKAEKQRRDLGEElealkteledtl 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1072 --AKIAVEAQNKYERELML-----------HAADV--------EALQAAKEQVSKMASVRQHLEETTQKAESQLLE---- 1126
Cdd:pfam01576  313 dtTAAQQELRSKREQEVTElkkaleeetrsHEAQLqemrqkhtQALEELTEQLEQAKRNKANLEKAKQALESENAElqae 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1127 ------CKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVvasvkEGVQGPLNVSLSEEGKSQEQILEIL 1200
Cdd:pfam01576  393 lrtlqqAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSEL-----ESVSSLLNEAEGKNIKLSKDVSSLE 467

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1201 RFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVM----ETN 1276
Cdd:pfam01576  468 SQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLealeEGK 547

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1277 KMLREEKERLEQDLQQMQAKVRKLELDILPLQEanaELSEKSGMLQAEKKLLEEDVKRWKARNQHL-----VSQQKDPDT 1351
Cdd:pfam01576  548 KRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQ---ELDDLLVDLDHQRQLVSNLEKKQKKFDQMLaeekaISARYAEER 624

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1352 EEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTI 1431
Cdd:pfam01576  625 DRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEEL 704

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1432 T---QVKKIGR-RYKTQYEELKAQQDKVMETSAQSSGDHQEQHV-SVQEMQ-ELKETLNQA----------ETKSKSLES 1495
Cdd:pfam01576  705 EdelQATEDAKlRLEVNMQALKAQFERDLQARDEQGEEKRRQLVkQVRELEaELEDERKQRaqavaakkklELDLKELEA 784

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1496 QVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQlrqqiTEKEEKTRKA-IVAAKSKIAHLAGVKDQL 1574
Cdd:pfam01576  785 QIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKE-----SEKKLKNLEAeLLQLQEDLAASERARRQA 859

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 1850342    1575 TKENEELKQR--NGALDQQKDELDvritalKSQYEGRISRLERELREHQ 1621
Cdd:pfam01576  860 QQERDELADEiaSGASGKSALQDE------KRRLEARIAQLEEELEEEQ 902
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
662-1139 2.61e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 2.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    662 STEAIEAKaaLKQLQEIFENYKKEKAENEKIQNE--QLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREI 739
Cdd:PRK03918  253 SKRKLEEK--IRELEERIEELKKEIEELEEKVKElkELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERI 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    740 TSLHERNQKLTATTQKQEQI---INTMTQDLRGANEKLAVAEiRAENLKKEKEMLKLSEVrlsqQRESLLAEQRGQNLLl 816
Cdd:PRK03918  331 KELEEKEERLEELKKKLKELekrLEELEERHELYEEAKAKKE-ELERLKKRLTGLTPEKL----EKELEELEKAKEEIE- 404

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    817 tnlqtiqgiLERSE-TETKQRLSSQIEKLEHEISHLKK--------KLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLH 887
Cdd:PRK03918  405 ---------EEISKiTARIGELKKEIKELKKAIEELKKakgkcpvcGRELTEEHRKELLEEYTAELKRIEKELKEIEEKE 475

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    888 LNTKELLKNAQKEIATLKRHLSNMEvqVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQA 967
Cdd:PRK03918  476 RKLRKELRELEKVLKKESELIKLKE--LAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    968 MVTSLEEsLNKEKQVTEEVRKNIEVRLKESAefqtqlEKKLMEVEKEKQELQDDKRRAIE--SMEQQLSELKKTLSSVQN 1045
Cdd:PRK03918  554 LKKKLAE-LEKKLDELEEELAELLKELEELG------FESVEELEERLKELEPFYNEYLElkDAEKELEREEKELKKLEE 626

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1046 EVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAAdvEALQAAKEQVSKMASVRQHLEETTQKAESQLL 1125
Cdd:PRK03918  627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELS--RELAGLRAELEELEKRREEIKKTLEKLKEELE 704

                         490
                  ....*....|....
gi 1850342   1126 ECKASWEERERMLK 1139
Cdd:PRK03918  705 EREKAKKELEKLEK 718
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 680-1427 2.69e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 52.80  E-value: 2.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     680 ENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTAttqKQEQI 759
Cdd:pfam05483   63 EGLKDSDFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSL---KLEEE 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     760 INTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSS 839
Cdd:pfam05483  140 IQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKE 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     840 QIEKleheISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNL---------HLNTKELLKNAQKEIATLKRHLSN 910
Cdd:pfam05483  220 DHEK----IQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLleesrdkanQLEEKTKLQDENLKELIEKKDHLT 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     911 MEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQ-TEEQVNDLKERLKTSTSN---VEQYQAMVTSLEESLNKEKQVTEEV 986
Cdd:pfam05483  296 KELEDIKMSLQRSMSTQKALEEDLQIATKTICQlTEEKEAQMEELNKAKAAHsfvVTEFEATTCSLEELLRTEQQRLEKN 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     987 RKNIEVRLKESAEFQTQLEKklMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARR 1066
Cdd:pfam05483  376 EDQLKIITMELQKKSSELEE--MTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIH 453

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1067 DCQEQAKIAVEAQNKYERELmlhaadvealqaaKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKdEVSKCV 1146
Cdd:pfam05483  454 DLEIQLTAIKTSEEHYLKEV-------------EDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTL-ELKKHQ 519

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1147 CRCEDLEKQNRLLHDQIEKLSDKvvasvkegvqgplnvslseEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQ 1226
Cdd:pfam05483  520 EDIINCKKQEERMLKQIENLEEK-------------------EMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEY 580

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1227 RVELLERELQELQDSLNAEREKVQvtaktmaqheelmKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILP 1306
Cdd:pfam05483  581 EVLKKEKQMKILENKCNNLKKQIE-------------NKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELAS 647

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1307 LQEANAELSEKSGMLQAEKKLLEE----DVKRWKARNQHLVSQQKDPDTEEYRKL-----LSEKEVHT--KRIQQLTEEI 1375
Cdd:pfam05483  648 AKQKFEEIIDNYQKEIEDKKISEEklleEVEKAKAIADEAVKLQKEIDKRCQHKIaemvaLMEKHKHQydKIIEERDSEL 727

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1850342    1376 GRLKAEIARSNAS-------LTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEK 1427
Cdd:pfam05483  728 GLYKNKEQEQSSAkaaleieLSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1193-1630 2.72e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.85  E-value: 2.72e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1193 QEQILEILRFIRREKEIAETRFEVAQVEsLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKtetmnvv 1272
Cdd:COG4717   52 EKEADELFKPQGRKPELNLKELKELEEE-LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK------- 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1273 METNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEanaelseksgmLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTE 1352
Cdd:COG4717  124 LLQLLPLYQELEALEAELAELPERLEELEERLEELRE-----------LEEELEELEAELAELQEELEELLEQLSLATEE 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1353 EYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEdlnkvrtEKETIQKDLDAKIIDIqekvkTIT 1432
Cdd:COG4717  193 ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAL-------EERLKEARLLLLIAAA-----LLA 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1433 QVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEAR 1512
Cdd:COG4717  261 LLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELL 340

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1513 NLQEQTVQLQSELSRLRQDlqdrtTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQK 1592
Cdd:COG4717  341 ELLDRIEELQELLREAEEL-----EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELL 415

                        410       420       430
                 ....*....|....*....|....*....|....*....
gi 1850342  1593 DELDVRITAL-KSQYEGRISRLERELREHQERHLEQRDE 1630
Cdd:COG4717  416 GELEELLEALdEEELEEELEELEEELEELEEELEELREE 454
PRK01156 PRK01156
chromosome segregation protein; Provisional
 926-1537 2.95e-06

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 52.98  E-value: 2.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    926 GQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQamvtSLEESLNKEKQVTEEVRKNIEvrlkESAEFQTQLE 1005
Cdd:PRK01156  146 GDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNID----YLEEKLKSSNLELENIKKQIA----DDEKSHSITL 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1006 KKLMEVEKEKQELQDDKRRAIESMeQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERE 1085
Cdd:PRK01156  218 KEIERLSIEYNNAMDDYNNLKSAL-NELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNY 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1086 LMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAEsqllECKASWEERERMLKdevskcvcRCEDLEKQnrllHDQIEK 1165
Cdd:PRK01156  297 INDYFKYKNDIENKKQILSNIDAEINKYHAIIKKLS----VLQKDYNDYIKKKS--------RYDDLNNQ----ILELEG 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1166 LSDKVVASVKEGVQgpLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAE 1245
Cdd:PRK01156  361 YEMDYNSYLKSIES--LKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALREN 438

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1246 REKVqvtaktmaqhEELMKKTETMNVVMETNKMLREEKER-----LEQDLQQMQAKVRKLELDILPLQEanaelsEKSGM 1320
Cdd:PRK01156  439 LDEL----------SRNMEMLNGQSVCPVCGTTLGEEKSNhiinhYNEKKSRLEEKIREIEIEVKDIDE------KIVDL 502

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1321 LQAEKKLLEEDVKRWKARNQHLVSQQKDPdTEEYRKLLSEKEVHTKrIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1400
Cdd:PRK01156  503 KKRKEYLESEEINKSINEYNKIESARADL-EDIKIKINELKDKHDK-YEEIKNRYKSLKLEDLDSKRTSWLNALAVISLI 580

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1401 eDLNKVRTEKETIQKDL---------------------DAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETS 1459
Cdd:PRK01156  581 -DIETNRSRSNEIKKQLndlesrlqeieigfpddksyiDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQI 659

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1850342   1460 AQSSGDHQEQhvsvqemQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTT 1537
Cdd:PRK01156  660 AEIDSIIPDL-------KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1467-1614 2.95e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 52.71  E-value: 2.95e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1467 QEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEA---------RNLQEQTVQLQSELSRLRQDLQDRTT 1537
Cdd:COG3206  212 EEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALpellqspviQQLRAQLAELEAELAELSARYTPNHP 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1538 QEEQLRQQI----TEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDV---RITALKSQYEGRI 1610
Cdd:COG3206  292 DVIALRAQIaalrAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRlerEVEVARELYESLL 371


                 ....
gi 1850342  1611 SRLE 1614
Cdd:COG3206  372 QRLE 375
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
29-372 3.66e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.46  E-value: 3.66e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    29 LADQQSEIDGLKGRHEKF------KVESEQQYFEIEKRLSHSQERL---------VNETRECQSLRLELEKLNNQLKALT 93
Cdd:COG4717   73 LKELEEELKEAEEKEEEYaelqeeLEELEEELEELEAELEELREELeklekllqlLPLYQELEALEAELAELPERLEELE 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    94 EKNKELEIAQDRNIAIQSQFTRTKEELEAEKRdliRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQA-- 171
Cdd:COG4717  153 ERLEELRELEEELEELEAELAELQEELEELLE---QLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEel 229

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   172 ----SDVSVKYREKRLEQEKELL--------HSQNTWLNTELKTKTDELLALG---------------REKGNEILELKC 224
Cdd:COG4717  230 eqleNELEAAALEERLKEARLLLliaaallaLLGLGGSLLSLILTIAGVLFLVlgllallflllarekASLGKEAEELQA 309

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   225 NLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFH--NELNAHIKLSNLYKSAADDSEAKSNE 302
Cdd:COG4717  310 LPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEelQLEELEQEIAALLAEAGVEDEEELRA 389

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1850342   303 LTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEML-EKIGRLEKEL-ENANDLLSATKRKGAILSE 372
Cdd:COG4717  390 ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELeEELEELEEELeELEEELEELREELAELEAE 461
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1243-1645 4.21e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.48  E-value: 4.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1243 NAEREKVQVTAKTMAQHEEL-----MKKTETMNVVMETNKMLREEKERLeqdlQQMQAKVRKLELDILPLQEANAELSEK 1317
Cdd:pfam01576   43 NALQEQLQAETELCAEAEEMrarlaARKQELEEILHELESRLEEEEERS----QQLQNEKKKMQQHIQDLEEQLDEEEAA 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1318 SGMLQAEKKLLEEDVKRWKARNQHLVSQQKdpdteeyrKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQ 1397
Cdd:pfam01576  119 RQKLQLEKVTTEAKIKKLEEDILLLEDQNS--------KLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMIS 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1398 SLKEDLN---KVRTEKETIQKDLDAKIIDIQEKVKTI-TQVKKIGRRYKTQYEELKAQQDKVMETSAQSSG---DHQEQH 1470
Cdd:pfam01576  191 DLEERLKkeeKGRQELEKAKRKLEGESTDLQEQIAELqAQIAELRAQLAKKEEELQAALARLEEETAQKNNalkKIRELE 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1471 VSVQEMQELKET----LNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRT----TQEEQL 1542
Cdd:pfam01576  271 AQISELQEDLESeraaRNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETrsheAQLQEM 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1543 RQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELdvritalksqyEGRISRLERELREHQE 1622
Cdd:pfam01576  351 RQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDS-----------EHKRKKLEGQLQELQA 419

                          410       420
                   ....*....|....*....|...
gi 1850342    1623 RHLEQRDEPQEPSNKVPEQQRQI 1645
Cdd:pfam01576  420 RLSESERQRAELAEKLSKLQSEL 442
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 978-1630 4.29e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.28  E-value: 4.29e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     978 KEKQVTEEVRKNIEVRLKESAEFQTQL------EKKLMEVEKEKQE---LQDDKRRAIESM-----EQQLSELKKTLSSV 1043
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLeelklqELKLKEQAKKALEyyqLKEKLELEEEYLlyldyLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1044 QNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMAS----VRQHLEETTQK 1119
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVddeeKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1120 AESQLLECKASWEERERMLKdEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNvSLSEEGKSQEQILEI 1199
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELK-ELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSS-AAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1200 LRFIRREKEIAETRFEVAQVESLRYRQRVELLEREL--QELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNK 1277
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIelKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1278 MLREE--KERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYR 1355
Cdd:pfam02463  484 EQLELllSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1356 KLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKdLDAKIIDIQEKVKTITQVK 1435
Cdd:pfam02463  564 QKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAK-VVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1436 KIGRRYKTQYEELKAQQDKVmETSAQSSGDHQEQHvsvqEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQ 1515
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKS-EVKASLSELTKELL----EIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1516 EQTVQLQSELSRL-------RQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGAL 1588
Cdd:pfam02463  718 EAEELLADRVQEAqdkineeLKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLK 797

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|..
gi 1850342    1589 DQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDE 1630
Cdd:pfam02463  798 AQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELA 839
PRK11281 PRK11281
mechanosensitive channel MscK;
744-1063 6.40e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.84  E-value: 6.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    744 ERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKE------KEMLKLSEVRLSQQRESLLAEQ-------- 809
Cdd:PRK11281   66 EQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDndeetrETLSTLSLRQLESRLAQTLDQLqnaqndla 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    810 --------------RGQNLLLTNLQTIQGI---LERSETETKQRLSSQIEKLEHEISHLKKKLENeveQRHTLTRNLDVQ 872
Cdd:PRK11281  146 eynsqlvslqtqpeRAQAALYANSQRLQQIrnlLKGGKVGGKALRPSQRVLLQAEQALLNAQNDL---QRKSLEGNTQLQ 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    873 LLDTKrQLDtETNLHLNtkellkNAQKEIATL------KRhLSNMEVQVA-SQSSQRTGKGQPS---------NKEDVDD 936
Cdd:PRK11281  223 DLLQK-QRD-YLTARIQ------RLEHQLQLLqeainsKR-LTLSEKTVQeAQSQDEAARIQANplvaqeleiNLQLSQR 293

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    937 LVSQ------LRQTEEQVNDLKERLKTSTSNV-EQYQAMVTSLEES--LNKEKQ------VTEEVRKNI-EVRLK--ESA 998
Cdd:PRK11281  294 LLKAteklntLTQQNLRVKNWLDRLTQSERNIkEQISVLKGSLLLSriLYQQQQalpsadLIEGLADRIaDLRLEqfEIN 373

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    999 EFQTQLE------KKLMevEKEKQELQDDKRRAIESM----EQQLSELKKTLSSVQNEV------QEALQRASTALSN-- 1060
Cdd:PRK11281  374 QQRDALFqpdayiDKLE--AGHKSEVTDEVRDALLQLlderRELLDQLNKQLNNQLNLAinlqlnQQQLLSVSDSLQStl 451


                  ...
gi 1850342   1061 EQQ 1063
Cdd:PRK11281  452 TQQ 454
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1-474 6.58e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 6.58e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     1 MAAVLQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFkvesEQQYFEIEKRLSHSQERLVNETRECQSLRL 80
Cdd:COG1196  339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL----AEELLEALRAAAELAAQLEELEEAEEALLE 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    81 ELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKG 160
Cdd:COG1196  415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   161 ELQLKLDELQASDVSVKYREKRLEQEK--ELLHSQNTWLNTELKTKTDELLALGREKGNEILE--LKCNLENKKEEVSRL 236
Cdd:COG1196  495 LLLEAEADYEGFLEGVKAALLLAGLRGlaGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEvaAAAIEYLKAAKAGRA 574

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   237 E----EQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHK 312
Cdd:COG1196  575 TflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE 654

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   313 LLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPG 392
Cdd:COG1196  655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   393 MKLTELYNAYVETQDQLLLEKLEnkrinkyLDEIVKEVEAKAPILKRQR-----------EEYERAQKAVASLSVK---L 458
Cdd:COG1196  735 EELLEELLEEEELLEEEALEELP-------EPPDLEELERELERLEREIealgpvnllaiEEYEELEERYDFLSEQredL 807

                        490
                 ....*....|....*.
gi 1850342   459 EQAMKEIQRLQEDTDK 474
Cdd:COG1196  808 EEARETLEEAIEEIDR 823
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 33-1049 7.02e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 51.98  E-value: 7.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      33 QSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNnqLKALTEKNKEL------------- 99
Cdd:TIGR01612  670 EDDIDALYNELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQNMETATVELH--LSNIENKKNELldiiveikkhihg 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     100 EIAQDRNIAIQSqFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQlkldelQASDVSVKYR 179
Cdd:TIGR01612  748 EINKDLNKILED-FKNKEKELSNKINDYAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAK------QNYDKSKEYI 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     180 EKRLEQEKELLHSQNtwlntELKTKTDELLAlgreKGNEILelkcNLENK-KEEVSRLEEQMNGL--KTSNEHLQKHVED 256
Cdd:TIGR01612  821 KTISIKEDEIFKIIN-----EMKFMKDDFLN----KVDKFI----NFENNcKEKIDSEHEQFAELtnKIKAEISDDKLND 887

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     257 LLTKLKEAK----EQQASMEEKFHN-----ELNAHIKLSnlyKSAADDSEAKSNELTRAVEELHKLLKEAGEANKaiqdh 327
Cdd:TIGR01612  888 YEKKFNDSKslinEINKSIEEEYQNintlkKVDEYIKIC---ENTKESIEKFHNKQNILKEILNKNIDTIKESNL----- 959

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     328 lleVEQS-KDQMEKEMLEKIGRLEKELENA---------NDLL--------SATKRKGAILSEEELAAMSPTAAAVAKIV 389
Cdd:TIGR01612  960 ---IEKSyKDKFDNTLIDKINELDKAFKDAslndyeaknNELIkyfndlkaNLGKNKENMLYHQFDEKEKATNDIEQKIE 1036

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     390 K-----PGMKL---TELYNAYVEtqdqllLEKLENKRINKYLDEIVKEVEakapilkrqreeyeraqkavasLSVKLEQA 461
Cdd:TIGR01612 1037 DankniPNIEIaihTSIYNIIDE------IEKEIGKNIELLNKEILEEAE----------------------INITNFNE 1088

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     462 MKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSssEVISQHLVSYR 541
Cdd:TIGR01612 1089 IKEKLKHYNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDL--EDVADKAISND 1166

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     542 NIEELQQQNQRLLVALrelgetREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQT 621
Cdd:TIGR01612 1167 DPEEIEKKIENIVTKI------DKKKNIYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEH 1240

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     622 TGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEA------IEAKAALKQLQEIFENYKK--EKAENEKIQ 693
Cdd:TIGR01612 1241 MIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDddkdhhIISKKHDENISDIREKSLKiiEDFSEESDI 1320

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     694 NEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQ--------DNVEGYRREItslHERNQKLTATTQKQEQIINTMTQ 765
Cdd:TIGR01612 1321 NDIKKELQKNLLDAQKHNSDINLYLNEIANIYNILKlnkikkiiDEVKEYTKEI---EENNKNIKDELDKSEKLIKKIKD 1397

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     766 DLrganeKLAVAEIRAENLKKEKEMLKLSEvRLSQQRESLLAEQRGQNLLLTNlqtiqgilERSETETKQRLSSQIEKLE 845
Cdd:TIGR01612 1398 DI-----NLEECKSKIESTLDDKDIDECIK-KIKELKNHILSEESNIDTYFKN--------ADENNENVLLLFKNIEMAD 1463

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     846 HEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLN----TKELLKNAQKEIATLKRHLSNMEVQVA-SQSS 920
Cdd:TIGR01612 1464 NKSQHILKIKKDNATNDHDFNINELKEHIDKSKGCKDEADKNAKaiekNKELFEQYKKDVTELLNKYSALAIKNKfAKTK 1543

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     921 QRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKT----STSNVEQYQAMV---TSLEESLNKEKQVTEeVRKNIEVR 993
Cdd:TIGR01612 1544 KDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRieddAAKNDKSNKAAIdiqLSLENFENKFLKISD-IKKKINDC 1622

                         1050      1060      1070      1080      1090      1100      1110
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     994 LKESAEFQTQL--------EKKLMEVEKEKQELQD------DKRRAIESMEQQLSELKKTLSSVQNEVQE 1049
Cdd:TIGR01612 1623 LKETESIEKKIssfsidsqDTELKENGDNLNSLQEfleslkDQKKNIEDKKKELDELDSEIEKIEIDVDQ 1692
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
408-865 7.11e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.31  E-value: 7.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   408 QLLLEKLENK---------RINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQ 478
Cdd:COG4717   45 AMLLERLEKEadelfkpqgRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   479 SSVLERDNRRMEI--QVKDLSQQIRVLLMELEEargnhvirdeevssadissssevISQHLVSYRNIEELQQQNQRLLVA 556
Cdd:COG4717  125 LQLLPLYQELEALeaELAELPERLEELEERLEE-----------------------LRELEEELEELEAELAELQEELEE 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   557 LRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQ----------RDMYRILLSQTTGVAI 626
Cdd:COG4717  182 LLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENEleaaaleerlKEARLLLLIAAALLAL 261

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   627 PLHASSLDDVSLASTPKR------PSTSQTVSTPAPVPVIESTEAIEAKAALKQL-QEIFENYKKEKAENEKIQNEQLEK 699
Cdd:COG4717  262 LGLGGSLLSLILTIAGVLflvlglLALLFLLLAREKASLGKEAEELQALPALEELeEEELEELLAALGLPPDLSPEELLE 341

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   700 LQEQVTDLRSQNTKIST------QLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEK 773
Cdd:COG4717  342 LLDRIEELQELLREAEEleeelqLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEEL 421

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   774 LAVAEirAENLKKEKEMLKLSEVRLSQQRESLLAEqrgqnllltnLQTIQGILERSETETkqrlssQIEKLEHEISHLKK 853
Cdd:COG4717  422 LEALD--EEELEEELEELEEELEELEEELEELREE----------LAELEAELEQLEEDG------ELAELLQELEELKA 483

                        490
                 ....*....|..
gi 1850342   854 KLENEVEQRHTL 865
Cdd:COG4717  484 ELRELAEEWAAL 495
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 618-1426 7.22e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.66  E-value: 7.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     618 LSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQL 697
Cdd:pfam15921   19 ITSNRGSSSPFFVSSIRGTIIENTSSTGTFTQIPIFPKYEVELDSPRKIIAYPGKEHIERVLEEYSHQVKDLQRRLNESN 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     698 EKLQEQVTDLRSQNTKISTQLdfasKRYEMLQDNVEGYRREitslhernqkltaTTQKQEQIINTMTQdlrganeklAVA 777
Cdd:pfam15921   99 ELHEKQKFYLRQSVIDLQTKL----QEMQMERDAMADIRRR-------------ESQSQEDLRNQLQN---------TVH 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     778 EIRAENLKKEkEMLKLSEVRLSQQRESLLAEQrgqnlllTNLQTIQGILERSETETKQRL------------------SS 839
Cdd:pfam15921  153 ELEAAKCLKE-DMLEDSNTQIEQLRKMMLSHE-------GVLQEIRSILVDFEEASGKKIyehdsmstmhfrslgsaiSK 224

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     840 QIEKLEHEISHLKKKL---ENEVEQRHTLTRNlDVQLLDTKRQLDTEtnlhlntkELLKNAQKEIATLKRHLSNMEVQVA 916
Cdd:pfam15921  225 ILRELDTEISYLKGRIfpvEDQLEALKSESQN-KIELLLQQHQDRIE--------QLISEHEVEITGLTEKASSARSQAN 295

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     917 S-QSSQRTGKGQPSNKEDVddLVSQLRQTEEQVNDLKERLKTSTsnvEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLK 995
Cdd:pfam15921  296 SiQSQLEIIQEQARNQNSM--YMRQLSDLESTVSQLRSELREAK---RMYEDKIEELEKQLVLANSELTEARTERDQFSQ 370

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     996 ESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQ------LSELKKTLSSVQNEVQ--EALQRAstalsneqqARRD 1067
Cdd:pfam15921  371 ESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDtgnsitIDHLRRELDDRNMEVQrlEALLKA---------MKSE 441

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1068 CQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLK---DEVSK 1144
Cdd:pfam15921  442 CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEatnAEITK 521

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1145 CVCRCeDLEKQ---------NRLLHDQIE----KLS----DKVVASVKEGVQGPLNVsLSEEGKSQEQILeiLRFIRREK 1207
Cdd:pfam15921  522 LRSRV-DLKLQelqhlknegDHLRNVQTEcealKLQmaekDKVIEILRQQIENMTQL-VGQHGRTAGAMQ--VEKAQLEK 597

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1208 EIAETRFEVAQVESLR------YRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTET----MNVVMETNK 1277
Cdd:pfam15921  598 EINDRRLELQEFKILKdkkdakIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTsrneLNSLSEDYE 677

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1278 MLR-------EEKE----RLEQDLQQMQAKVRKLELDILPLQEANA-----------ELSEKSGM---LQAEKKLLEEDV 1332
Cdd:pfam15921  678 VLKrnfrnksEEMEtttnKLKMQLKSAQSELEQTRNTLKSMEGSDGhamkvamgmqkQITAKRGQidaLQSKIQFLEEAM 757

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1333 ------KRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQslkedlnkv 1406
Cdd:pfam15921  758 tnankeKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ--------- 828

                          890       900
                   ....*....|....*....|
gi 1850342    1407 RTEKETIQKDLDaKIIDIQE 1426
Cdd:pfam15921  829 RQEQESVRLKLQ-HTLDVKE 847
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1475-1641 7.40e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.54  E-value: 7.40e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1475 EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKeeKTR 1554
Cdd:COG1579   11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNV--RNN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1555 KAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDEPQEP 1634
Cdd:COG1579   89 KEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168


                 ....*..
gi 1850342  1635 SNKVPEQ 1641
Cdd:COG1579  169 AAKIPPE 175
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 32-495 7.56e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 51.26  E-value: 7.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      32 QQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTE--KNKELEIAQDRNIAI 109
Cdd:pfam05483  336 QMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKfkNNKEVELEELKKILA 415

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     110 QsqftrtKEELEAEKRDLirtnERLSQELEYLTEDVKRLNEKlKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKEL 189
Cdd:pfam05483  416 E------DEKLLDEKKQF----EKIAEELKGKEQELIFLLQA-REKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEK 484

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     190 LHsqntwlNTELKTKTDELL----ALGREKGNEILELKCNLE---NKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLK 262
Cdd:pfam05483  485 LK------NIELTAHCDKLLlenkELTQEASDMTLELKKHQEdiiNCKKQEERMLKQIENLEEKEMNLRDELESVREEFI 558

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     263 EAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHllEVEQSKDQMEKEM 342
Cdd:pfam05483  559 QKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKK--GSAENKQLNAYEI 636

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     343 leKIGRLEKELENAN----DLLSATKRKGAI--LSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLEN 416
Cdd:pfam05483  637 --KVNKLELELASAKqkfeEIIDNYQKEIEDkkISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKH 714

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1850342     417 KrinkyLDEIVKEVEAKAPILKRQREEYERAQkavASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKD 495
Cdd:pfam05483  715 Q-----YDKIIEERDSELGLYKNKEQEQSSAK---AALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 70-509 7.90e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.17  E-value: 7.90e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      70 NETREcQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLN 149
Cdd:TIGR04523   31 QDTEE-KQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKIN 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     150 EKLKESNTTKGELQLKLDELqasdvsvkyrEKRLEQEKELLhsqnTWLNTELKTKTDELLALGrEKGNEILELKCNLENK 229
Cdd:TIGR04523  110 SEIKNDKEQKNKLEVELNKL----------EKQKKENKKNI----DKFLTEIKKKEKELEKLN-NKYNDLKKQKEELENE 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     230 KEEVSR--LEEQMNGLKTSNEHLQKHVedLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAV 307
Cdd:TIGR04523  175 LNLLEKekLNIQKNIDKIKNKLLKLEL--LLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQ 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     308 EELHKLLKEAGEANKAIQDHLLEVEQSKDQMeKEMLEKIGRLEKELENAN-------------DLLSATKRKGAILSE-- 372
Cdd:TIGR04523  253 TQLNQLKDEQNKIKKQLSEKQKELEQNNKKI-KELEKQLNQLKSEISDLNnqkeqdwnkelksELKNQEKKLEEIQNQis 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     373 EELAAMSPTAAAVAKIVKpgmKLTELYNAYVETQDQL-----LLEKLeNKRINKYLDEIvKEVEAKAPILKRQREEYERA 447
Cdd:TIGR04523  332 QNNKIISQLNEQISQLKK---ELTNSESENSEKQRELeekqnEIEKL-KKENQSYKQEI-KNLESQINDLESKIQNQEKL 406

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1850342     448 ----QKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEE 509
Cdd:TIGR04523  407 nqqkDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKV 472
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
110-511 7.91e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 7.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    110 QSQFTRTKEELEA-EKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQL----------KLDELQA------S 172
Cdd:PRK02224  186 RGSLDQLKAQIEEkEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEvleeheerreELETLEAeiedlrE 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    173 DVSVKYREKrlEQEKELLHSQNTWLNtELKTKTDELLA---LGREKGNEILELKCNLENKKEEV-SRLEEQMNGLKTSN- 247
Cdd:PRK02224  266 TIAETERER--EELAEEVRDLRERLE-ELEEERDDLLAeagLDDADAEAVEARREELEDRDEELrDRLEECRVAAQAHNe 342

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    248 --EHLQKHVEDLLTKLKEAKEQQASMEEKFHNElnahiklsnlyKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQ 325
Cdd:PRK02224  343 eaESLREDADDLEERAEELREEAAELESELEEA-----------REAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    326 DHLLEVEQSKD---QMEKEMLEKIGRLEKELENANDLLSATK--------------------RKGAILSEEELAAMSPTA 382
Cdd:PRK02224  412 DFLEELREERDelrEREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvetieedRERVEELEAELEDLEEEV 491

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    383 AAVAKIVKPGMKLtelynayVETQDQllLEKLENKRinkylDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAM 462
Cdd:PRK02224  492 EEVEERLERAEDL-------VEAEDR--IERLEERR-----EDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKR 557

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 1850342    463 KEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLsQQIRVLLMELEEAR 511
Cdd:PRK02224  558 EAAAEAEEEAEEAREEVAELNSKLAELKERIESL-ERIRTLLAAIADAE 605
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 70-370 8.12e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 8.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      70 NETRECQSLRLELEKLnnqlkALTEKNKELEIAQDRNIAIQSQFtrtkEELEAEKRDLIRTNERLSQELEYLTEDVKRLN 149
Cdd:TIGR02169  208 EKAERYQALLKEKREY-----EGYELLKEKEALERQKEAIERQL----ASLEEELEKLTEEISELEKRLEEIEQLLEELN 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     150 EKLKE-SNTTKGELQLKLDELQASDVSVKYREKRLEQEKEllhsqntwlntELKTKTDELLALGREKGNEILELKCNLEN 228
Cdd:TIGR02169  279 KKIKDlGEEEQLRVKEKIGELEAEIASLERSIAEKERELE-----------DAEERLAKLEAEIDKLLAEIEELEREIEE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     229 KKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKF------HNELNAHI-KLSNLYKSAADDSEAKSN 301
Cdd:TIGR02169  348 ERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLeklkreINELKRELdRLQEELQRLSEELADLNA 427

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1850342     302 ELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMlEKIGRLEKELENANDLLSATKRKGAIL 370
Cdd:TIGR02169  428 AIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE-QELYDLKEEYDRVEKELSKLQRELAEA 495
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 167-501 8.35e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.60  E-value: 8.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     167 DELQASDVSVKYREKRLEQEKELLHSQNTWLNTEL---KTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGL 243
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALaelRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     244 KTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFH------NELNAHI-KLSNLYKSAADDSEAKSNELTRAVEELHKL--- 313
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAeaeaeiEELEAQIeQLKEELKALREALDELRAELTLLNEEAANLrer 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     314 LKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAA---AVAKIVK 390
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEleeLSEELRE 905

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     391 PGMKLTELYNAYVETQD-----QLLLEKLENKRINKY----------LDEIVKEVEAKAPILKRQREEYERAQKAVASLS 455
Cdd:TIGR02168  906 LESKRSELRRELEELREklaqlELRLEGLEVRIDNLQerlseeysltLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1850342     456 VKLEQAMKEIQRLQEDTDKANKQS-----------SVLERDNRRMEIQVKDLSQQIR 501
Cdd:TIGR02168  986 PVNLAAIEEYEELKERYDFLTAQKedlteaketleEAIEEIDREARERFKDTFDQVN 1042
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1274-1565 8.83e-06

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 49.91  E-value: 8.83e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1274 ETNKMLREEKERLEQDLQQMQAKVRKLELDilpLQEANAELSEksgmLQAEKKLLEEDVKRWKARNQHLVsQQKDPDTEE 1353
Cdd:COG1340    1 SKTDELSSSLEELEEKIEELREEIEELKEK---RDELNEELKE----LAEKRDELNAQVKELREEAQELR-EKRDELNEK 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1354 YRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASltnnqnliqslKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQ 1433
Cdd:COG1340   73 VKELKEERDELNEKLNELREELDELRKELAELNKA-----------GGSIDKLRKEIERLEWRQQTEVLSPEEEKELVEK 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1434 VKKIGRRYKTQYEELKaQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKtlseketEARN 1513
Cdd:COG1340  142 IKELEKELEKAKKALE-KNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRK-------EADE 213

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 1850342  1514 LQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIA 1565
Cdd:COG1340  214 LHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEEL 265
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 662-870 1.08e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 1.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   662 STEAIEAKAALKQLQEIFENYKKEKAENEKIQNE---QLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRRE 738
Cdd:COG4942   19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKAllkQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   739 ITSLHERNQKLTATTQKQEQIINTM----TQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNL 814
Cdd:COG4942   99 LEAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 1850342   815 LLTNLQTIQGILERSETETKQRLSsqieKLEHEISHLKKKLENEVEQRHTLTRNLD 870
Cdd:COG4942  179 LLAELEEERAALEALKAERQKLLA----RLEKELAELAAELAELQQEAEELEALIA 230
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
145-595 1.25e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   145 VKRLNEKLKESNTTKGEL-QLKLDELQASDVSVKYREKRLEQEKELLHSQNTwLNTELKTKTDELLALGREKGNeiLELK 223
Cdd:COG4717   48 LERLEKEADELFKPQGRKpELNLKELKELEEELKEAEEKEEEYAELQEELEE-LEEELEELEAELEELREELEK--LEKL 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   224 CNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKfHNELNAHIKLSNLYKsaaddsEAKSNEL 303
Cdd:COG4717  125 LQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAEL-QEELEELLEQLSLAT------EEELQDL 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   304 TRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMlEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAA 383
Cdd:COG4717  198 AEELEELQQRLAELEEELEEAQEELEELEEELEQLENEL-EAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIA 276

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   384 AVAKIV---------KPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASL 454
Cdd:COG4717  277 GVLFLVlgllallflLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREA 356

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   455 SVKLEQAmkEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHvirDEEVSSADISSSSEVIS 534
Cdd:COG4717  357 EELEEEL--QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEEL---LGELEELLEALDEEELE 431

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1850342   535 QHLVSYRniEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRK 595
Cdd:COG4717  432 EELEELE--EELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAE 490
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1240-1633 1.40e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.49  E-value: 1.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1240 DSLNAEREKVQVTAKTMAQHEELMKktETMNVVMETNKMLREEKErleqdlQQMQAKVRKLELDILPLQEANAELSEKSG 1319
Cdd:pfam05483  292 DHLTKELEDIKMSLQRSMSTQKALE--EDLQIATKTICQLTEEKE------AQMEELNKAKAAHSFVVTEFEATTCSLEE 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1320 MLQAEKKLLEEDVKRWKARNQHLvsQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSL 1399
Cdd:pfam05483  364 LLRTEQQRLEKNEDQLKIITMEL--QKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQEL 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1400 KEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSgdhQEQHVSVQEMQEL 1479
Cdd:pfam05483  442 IFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELT---QEASDMTLELKKH 518

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1480 KETLNQAETKSKSLESQVENLQktlsEKETEARNLQEQtvqLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVA 1559
Cdd:pfam05483  519 QEDIINCKKQEERMLKQIENLE----EKEMNLRDELES---VREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKI 591

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1850342    1560 AKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITAlksqYEGRISRLERELREHQERHLEQRDEPQE 1633
Cdd:pfam05483  592 LENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNA----YEIKVNKLELELASAKQKFEEIIDNYQK 661
PLN02939 PLN02939
transferase, transferring glycosyl groups
 706-1046 1.51e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 50.67  E-value: 1.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    706 DLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSlhERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENL- 784
Cdd:PLN02939   57 KQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTS--SDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQLEDLv 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    785 ----KKEKEMLKLSEVRLS--QQRESLLAE----QRGQNLLLTNLqtiqgilerSETETKQRLSSQiEKLEHEI-SHLKK 853
Cdd:PLN02939  135 gmiqNAEKNILLLNQARLQalEDLEKILTEkealQGKINILEMRL---------SETDARIKLAAQ-EKIHVEIlEEQLE 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    854 KLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLK-------NAQKEIATLKRHLSNMEVQVASQSSQRTgkg 926
Cdd:PLN02939  205 KLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKaelievaETEERVFKLEKERSLLDASLRELESKFI--- 281

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    927 qpSNKEDVDDLVS-QLRQTEEQVNDLKERLKTSTSNVEQYqAMVTSLEESLNKEKQVTEEVRKNIEVRlKESAEFQTQLE 1005
Cdd:PLN02939  282 --VAQEDVSKLSPlQYDCWWEKVENLQDLLDRATNQVEKA-ALVLDQNQDLRDKVDKLEASLKEANVS-KFSSYKVELLQ 357

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1850342   1006 KKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNE 1046
Cdd:PLN02939  358 QKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEE 398
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
724-1337 1.69e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 1.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    724 RYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRE 803
Cdd:PRK03918  159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    804 SLLAEQRGQNLLLTNLqtiqgileRSETETKQRLSSQIEKLEHEISHLKKKLE--NEVEQRHTLTRNLdvqlldtkrqld 881
Cdd:PRK03918  239 EIEELEKELESLEGSK--------RKLEEKIRELEERIEELKKEIEELEEKVKelKELKEKAEEYIKL------------ 298

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    882 teTNLHLNTKELLKNAQKEIATLKRHLSNMEVQVasqssqrtgkgqpsnkEDVDDLVSQLRQTEEQVNDLKERLKTSTSN 961
Cdd:PRK03918  299 --SEFYEEYLDELREIEKRLSRLEEEINGIEERI----------------KELEEKEERLEELKKKLKELEKRLEELEER 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    962 VEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD---DKRRAIESMEQQ------ 1032
Cdd:PRK03918  361 HELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKeikELKKAIEELKKAkgkcpv 440

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1033 -------------LSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVE---AQNKYERELMLHAADVEAL 1096
Cdd:PRK03918  441 cgrelteehrkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLkelAEQLKELEEKLKKYNLEEL 520

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1097 QAAKEQVSKmasvrqhLEETTQKAESQLLECKASWeERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKE 1176
Cdd:PRK03918  521 EKKAEEYEK-------LKEKLIKLKGEIKSLKKEL-EKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE 592

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1177 gvqgplnvSLSEEGKSQEQILEiLRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVtaktm 1256
Cdd:PRK03918  593 --------RLKELEPFYNEYLE-LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE----- 658

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1257 aqhEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELsEKSGMLQAEKKLLEEDVKRWK 1336
Cdd:PRK03918  659 ---EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKEL-EKLEKALERVEELREKVKKYK 734


                  .
gi 1850342   1337 A 1337
Cdd:PRK03918  735 A 735
46 PHA02562
endonuclease subunit; Provisional
 1313-1535 2.02e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 49.63  E-value: 2.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1313 ELSEKSGMLQAEKKLLEEDVKrwkARNQHLVSQQKDPDTEEYRKllsekevhTKRIQQLTEEIGRLKAEIARSNASLTNN 1392
Cdd:PHA02562  178 ELNQQIQTLDMKIDHIQQQIK---TYNKNIEEQRKKNGENIARK--------QNKYDELVEEAKTIKAEIEELTDELLNL 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1393 QNLIQSLKEDLNKVRTEKETIQKDLD--AKII--------------DIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVM 1456
Cdd:PHA02562  247 VMDIEDPSAALNKLNTAAAKIKSKIEqfQKVIkmyekggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDTAIDELE 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1457 ETSAQssgdHQEQHVSVQEMQELKETLNQA----ETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDL 1532
Cdd:PHA02562  327 EIMDE----FNEQSKKLLELKNKISTNKQSlitlVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEK 402


                  ...
gi 1850342   1533 QDR 1535
Cdd:PHA02562  403 YHR 405
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
143-596 2.22e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.06  E-value: 2.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    143 EDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREK------G 216
Cdd:PRK03918  158 DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVkeleelK 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    217 NEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEE-----KFHNELNAHI-------- 283
Cdd:PRK03918  238 EEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyiklsEFYEEYLDELreiekrls 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    284 KLSNLYK------SAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENAN 357
Cdd:PRK03918  318 RLEEEINgieeriKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELE 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    358 --------DLLSATKRKGAILSEEE--LAAMSPTAAAVAKIVKPGMKLTE-----LYNAYVETQDQLLLEKLENKRINKY 422
Cdd:PRK03918  398 kakeeieeEISKITARIGELKKEIKelKKAIEELKKAKGKCPVCGRELTEehrkeLLEEYTAELKRIEKELKEIEEKERK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    423 LDEIVKEVE---AKAPILKRQREEYERAQKAVASLSV----KLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEiQVKD 495
Cdd:PRK03918  478 LRKELRELEkvlKKESELIKLKELAEQLKELEEKLKKynleELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE-ELKK 556

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    496 LSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELgeTREREEQETTSSK 575
Cdd:PRK03918  557 KLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKEL--KKLEEELDKAFEE 634

                         490       500
                  ....*....|....*....|.
gi 1850342    576 ITELQLKLESALTELEQLRKS 596
Cdd:PRK03918  635 LAETEKRLEELRKELEELEKK 655
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
819-1299 2.46e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.65  E-value: 2.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    819 LQTIQGILERSET--ETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDvQLLDTKRQLDTETNLHLNTKELLKN 896
Cdd:PRK02224  236 RDEADEVLEEHEErrEELETLEAEIEDLRETIAETEREREELAEEVRDLRERLE-ELEEERDDLLAEAGLDDADAEAVEA 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    897 AQKEIATLKRHLSNmEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLE--- 973
Cdd:PRK02224  315 RREELEDRDEELRD-RLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEeei 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    974 ESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRA------------------------IESM 1029
Cdd:PRK02224  394 EELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAealleagkcpecgqpvegsphvetIEED 473

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1030 EQQLSELKKTLSSV---QNEVQEALQRASTALSNEQQARRdCQEQAKIAVEAQNKYERELmlhAADVEALQAAKEQVSKM 1106
Cdd:PRK02224  474 RERVEELEAELEDLeeeVEEVEERLERAEDLVEAEDRIER-LEERREDLEELIAERRETI---EEKRERAEELRERAAEL 549

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1107 ASVRQHLEETTQKAESQLLECKasweERERMLKDEVSKCVCRCEDLEKQNRLLhDQIEKLSDKVvasvkegvqGPLNVSL 1186
Cdd:PRK02224  550 EAEAEEKREAAAEAEEEAEEAR----EEVAELNSKLAELKERIESLERIRTLL-AAIADAEDEI---------ERLREKR 615

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1187 SEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRY-RQRVELLERELQELQDSLNAEREKVQVTA----KTMAQHEE 1261
Cdd:PRK02224  616 EALAELNDERRERLAEKRERKRELEAEFDEARIEEAREdKERAEEYLEQVEEKLDELREERDDLQAEIgaveNELEELEE 695

                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 1850342   1262 LMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRK 1299
Cdd:PRK02224  696 LRERREALENRVEALEALYDEAEELESMYGDLRAELRQ 733
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1365-1630 2.64e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 2.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1365 TKRIQQLTEEIGRLKAEIARSNASltnnqnlIQSLKEDLNKVRTEKETIQK--DLDAKIIDIQEKVKTITQVKKigrryk 1442
Cdd:COG4913  609 RAKLAALEAELAELEEELAEAEER-------LEALEAELDALQERREALQRlaEYSWDEIDVASAEREIAELEA------ 675

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1443 tQYEELKAQQDKVMETSAQSSGdhqeqhvSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQ 1522
Cdd:COG4913  676 -ELERLDASSDDLAALEEQLEE-------LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL 747

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1523 SEL--SRLRQDLQDRttQEEQLRQQITEKEEKTRKAIVAAKSKIAhlagvkDQLTKENEELKQRNGALDQQKDELDvrit 1600
Cdd:COG4913  748 RALleERFAAALGDA--VERELRENLEERIDALRARLNRAEEELE------RAMRAFNREWPAETADLDADLESLP---- 815

                        250       260       270
                 ....*....|....*....|....*....|.
gi 1850342  1601 alksQYEGRISRLERE-LREHQERHLEQRDE 1630
Cdd:COG4913  816 ----EYLALLDRLEEDgLPEYEERFKELLNE 842
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
929-1124 2.71e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   929 SNKEDVDDLVSQLRQTEEQVNDLKERLktstsnvEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRlkesaefqtQLEKKL 1008
Cdd:COG4913  607 DNRAKLAALEAELAELEEELAEAEERL-------EALEAELDALQERREALQRLAEYSWDEIDVA---------SAEREI 670

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1009 MEVEKEKQELQDDKRrAIESMEQQLSELKKTLSSVQNEVqEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELML 1088
Cdd:COG4913  671 AELEAELERLDASSD-DLAALEEQLEELEAELEELEEEL-DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR 748

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 1850342  1089 HAADVEALQAAKEQVSKmaSVRQHLEETTQKAESQL 1124
Cdd:COG4913  749 ALLEERFAAALGDAVER--ELRENLEERIDALRARL 782
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
825-1059 2.71e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   825 ILERSETETK-QRLSSQIEKLE--HEIshlkkkLENEVEQRHTLTR--------NLDVQLLDTKRQLDTETNLHLNTKEL 893
Cdd:COG4913  217 MLEEPDTFEAaDALVEHFDDLEraHEA------LEDAREQIELLEPirelaeryAAARERLAELEYLRAALRLWFAQRRL 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   894 LKnAQKEIATLKRHLSNMEVQVASQSSQRTgkgqpSNKEDVDDLVSQLRQT--------EEQVNDLKERLKTSTSNVEQY 965
Cdd:COG4913  291 EL-LEAELEELRAELARLEAELERLEARLD-----ALREELDELEAQIRGNggdrleqlEREIERLERELEERERRRARL 364

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   966 QAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAiesmEQQLSELKKTLSSVQN 1045
Cdd:COG4913  365 EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELREL----EAEIASLERRKSNIPA 440

                        250
                 ....*....|....
gi 1850342  1046 EVQEALQRASTALS 1059
Cdd:COG4913  441 RLLALRDALAEALG 454
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 815-1561 2.87e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.63  E-value: 2.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     815 LLTNLQTIQGILERSETETKQRLSSQIEKLEHeishlKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELL 894
Cdd:TIGR04523   38 LEKKLKTIKNELKNKEKELKNLDKNLNKDEEK-----INNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEI 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     895 KNAQKEIATLKRHLSNMEVQVAsqssqrtgkgqpSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEE 974
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKLEKQKK------------ENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     975 SLNKEKQVTEEVRKNIEVR------LKESAEFQTQLEKKLMEVEKEKQELQDDkrraIESMEQQLSELKKTLSSVQNEVQ 1048
Cdd:TIGR04523  181 EKLNIQKNIDKIKNKLLKLelllsnLKKKIQKNKSLESQISELKKQNNQLKDN----IEKKQQEINEKTTEISNTQTQLN 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1049 EalqrastaLSNEQQARRDCQEQAKIAVEAQNKYERELMlhaadvEALQAAKEQVSKMASVRQhlEETTQKAESQLleck 1128
Cdd:TIGR04523  257 Q--------LKDEQNKIKKQLSEKQKELEQNNKKIKELE------KQLNQLKSEISDLNNQKE--QDWNKELKSEL---- 316

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1129 ASWEERERMLKDEVSKCvcrcedlEKQNRLLHDQIEKLSDKVVASVKEgvqgplNVSLSEEGKSQEQILEILrfirrEKE 1208
Cdd:TIGR04523  317 KNQEKKLEEIQNQISQN-------NKIISQLNEQISQLKKELTNSESE------NSEKQRELEEKQNEIEKL-----KKE 378

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1209 IAETRFEVAQVESlryrqrvellerelqelqdSLNAEREKVQVTAKTMAQHEELMKKtetmnvvmetnkmLREEKERLEQ 1288
Cdd:TIGR04523  379 NQSYKQEIKNLES-------------------QINDLESKIQNQEKLNQQKDEQIKK-------------LQQEKELLEK 426

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1289 DLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKArnqhlvsqqkdpdteEYRKLLSEKEVHTKRI 1368
Cdd:TIGR04523  427 EIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR---------------SINKIKQNLEQKQKEL 491

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1369 QQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKdldaKIIDIQEKVKTITQVKKigrryKTQYEEL 1448
Cdd:TIGR04523  492 KSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKES----KISDLEDELNKDDFELK-----KENLEKE 562

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1449 KAQQDKVMETSaqssgdHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRL 1528
Cdd:TIGR04523  563 IDEKNKEIEEL------KQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNI 636

                          730       740       750
                   ....*....|....*....|....*....|...
gi 1850342    1529 RQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAK 1561
Cdd:TIGR04523  637 KSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIK 669
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 84-373 3.33e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 49.12  E-value: 3.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      84 KLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQ 163
Cdd:pfam07888   35 RLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELS 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     164 LKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILE---LKCNLENKKEEVSRLEEQM 240
Cdd:pfam07888  115 EEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAErkqLQAKLQQTEEELRSLSKEF 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     241 NGLK-------TSNEHLQKHVEDLLTKLKEAKEQQASMEEkFHNELNAHIKLSNLYKSAAD----DSEAKSNELTRAVEE 309
Cdd:pfam07888  195 QELRnslaqrdTQVLQLQDTITTLTQKLTTAHRKEAENEA-LLEELRSLQERLNASERKVEglgeELSSMAAQRDRTQAE 273

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1850342     310 LHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEE 373
Cdd:pfam07888  274 LHQARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEE 337
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 12-274 3.54e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.25  E-value: 3.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      12 TELNKLPKSVQNkLEKFLADQQSEIDGLKGR----------HEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLE 81
Cdd:TIGR04523  419 QEKELLEKEIER-LKETIIKNNSEIKDLTNQdsvkeliiknLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE 497

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      82 LEKLNNQLKALTEKNKELEiaqdrniAIQSQFTRTKEELEAEKRdlirtneRLSQELEYLTEDVKRLNEKLKESNtTKGE 161
Cdd:TIGR04523  498 LKKLNEEKKELEEKVKDLT-------KKISSLKEKIEKLESEKK-------EKESKISDLEDELNKDDFELKKEN-LEKE 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     162 LQLKLDELqasdvsvkyreKRLEQEKELLHSQNTWLNTELKTKTDELLALGRE---KGNEILELKCNLENKKEEVSRLEE 238
Cdd:TIGR04523  563 IDEKNKEI-----------EELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEieeKEKKISSLEKELEKAKKENEKLSS 631

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1850342     239 QMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEK 274
Cdd:TIGR04523  632 IIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKK 667
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 39-521 4.11e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 48.95  E-value: 4.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      39 LKGRHEKFKVESEQQYFEI---EKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTR 115
Cdd:pfam05483  217 LKEDHEKIQHLEEEYKKEIndkEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTK 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     116 TKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNE----KLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLH 191
Cdd:pfam05483  297 ELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEekeaQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     192 SQNTWLNTELKTKTDELLALGREKGNEILELK----------------------------------CNLENKKEEVSRLE 237
Cdd:pfam05483  377 DQLKIITMELQKKSSELEEMTKFKNNKEVELEelkkilaedeklldekkqfekiaeelkgkeqeliFLLQAREKEIHDLE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     238 EQMNGLKTSNEHLQKHVEDLLTKLKEAKEQqasmeekfHNELNAHIKLSNLyksaaddseaksneltraveELHKLLKEA 317
Cdd:pfam05483  457 IQLTAIKTSEEHYLKEVEDLKTELEKEKLK--------NIELTAHCDKLLL--------------------ENKELTQEA 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     318 GEANKAIQDHLLEVEQSKDQmEKEMLEKIGRLEKELENANDLLSATkRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTE 397
Cdd:pfam05483  509 SDMTLELKKHQEDIINCKKQ-EERMLKQIENLEEKEMNLRDELESV-REEFIQKGDEVKCKLDKSEENARSIEYEVLKKE 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     398 LYNAYVETQDQLLLEKLENKriNKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQedtdkank 477
Cdd:pfam05483  587 KQMKILENKCNNLKKQIENK--NKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEII-------- 656

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1850342     478 qssvlerDNRRMEIQVKDLSQQirVLLMELEEARgnhVIRDEEV 521
Cdd:pfam05483  657 -------DNYQKEIEDKKISEE--KLLEEVEKAK---AIADEAV 688
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2-214 4.32e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 4.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     2 AAVLQQVLERTELNKLPKSVQNKL---EKFLADQQSEIDGLKGRHEkfkvESEQQYFEIEKRLSHSQERLVNETRECQSL 78
Cdd:COG4942   13 LAAAAQADAAAEAEAELEQLQQEIaelEKELAALKKEEKALLKQLA----ALERRIAALARRIRALEQELAALEAELAEL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    79 RLELEKLNNQLKALTEKNKELEIAQDRNiaiqSQFTRTKEELEAEK-RDLIRTNERLSQELEYLTEDVKRLNEKLKESNT 157
Cdd:COG4942   89 EKEIAELRAELEAQKEELAELLRALYRL----GRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 1850342   158 TKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGRE 214
Cdd:COG4942  165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1280-1419 4.33e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 48.70  E-value: 4.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1280 REEKERLEQDLQQMQAKVRKLEldilplqeanaelsEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLS 1359
Cdd:COG2433  398 EREKEHEERELTEEEEEIRRLE--------------EQVERLEAEVEELEAELEEKDERIERLERELSEARSEERREIRK 463

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1360 EKEvhtkrIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDA 1419
Cdd:COG2433  464 DRE-----ISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGELVPVKVVEK 518
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1276-1640 4.44e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.88  E-value: 4.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1276 NKMLREEKERLEQDLQQMQAKVRK--------LELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHL--VSQ 1345
Cdd:PRK02224  179 ERVLSDQRGSLDQLKAQIEEKEEKdlherlngLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELetLEA 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1346 QKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQ 1425
Cdd:PRK02224  259 EIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQ 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1426 EKVKTITQVKKIGRRYKTQYEELKAQQDKVMEtsaqssgdhqeqhvsvqEMQELKETLNQAETKSKSLESQVENLQKTLS 1505
Cdd:PRK02224  339 AHNEEAESLREDADDLEERAEELREEAAELES-----------------ELEEAREAVEDRREEIEELEEEIEELRERFG 401

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1506 EKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEE-------KTRKAIVAAKSKIAHLAGVKDQLTKEN 1578
Cdd:PRK02224  402 DAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAlleagkcPECGQPVEGSPHVETIEEDRERVEELE 481

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1850342   1579 EELKQrngaLDQQKDELDVRITALKS--QYEGRISRLERELREHQERHLEQRDEPQEPSNKVPE 1640
Cdd:PRK02224  482 AELED----LEEEVEEVEERLERAEDlvEAEDRIERLEERREDLEELIAERRETIEEKRERAEE 541
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 6-511 5.15e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.96  E-value: 5.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342       6 QQVLERTELNKLP-KSVQNKLEKFLADQQSEIDGLKGR-------HEKFKVESE--------QQYFEIEKRLSHSQERLV 69
Cdd:pfam15921  202 KKIYEHDSMSTMHfRSLGSAISKILRELDTEISYLKGRifpvedqLEALKSESQnkielllqQHQDRIEQLISEHEVEIT 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      70 NETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIaiqSQFTRTKEELEAEKRDLIRTNERLSQELEyltEDVKRLN 149
Cdd:pfam15921  282 GLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQL---SDLESTVSQLRSELREAKRMYEDKIEELE---KQLVLAN 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     150 EKLKESNTTKGELQLKL----DELQASDVSVKYREKRLEQEKEllHSQNTW------------LNTELKTKTDELLAL-- 211
Cdd:pfam15921  356 SELTEARTERDQFSQESgnldDQLQKLLADLHKREKELSLEKE--QNKRLWdrdtgnsitidhLRRELDDRNMEVQRLea 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     212 ------------------GREKGNEILE----LKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEaKEQQA 269
Cdd:pfam15921  434 llkamksecqgqmerqmaAIQGKNESLEkvssLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQE-KERAI 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     270 SMEEKFHNELNAHIKLSnlyksaaddseaksneltraVEELHKLLKEageankaiQDHLLEVEQSKDQMEKEMLEK---I 346
Cdd:pfam15921  513 EATNAEITKLRSRVDLK--------------------LQELQHLKNE--------GDHLRNVQTECEALKLQMAEKdkvI 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     347 GRLEKELENANDLLSATKRK-GAILSEEelaamsptaaavAKIVKpgmkltELYNAYVETQDqllLEKLENKRinkylDE 425
Cdd:pfam15921  565 EILRQQIENMTQLVGQHGRTaGAMQVEK------------AQLEK------EINDRRLELQE---FKILKDKK-----DA 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     426 IVKEVEAKAPILKRQREEYERAQ----KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNR----RMEIQVKDLS 497
Cdd:pfam15921  619 KIRELEARVSDLELEKVKLVNAGserlRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRnkseEMETTTNKLK 698

                          570
                   ....*....|....
gi 1850342     498 QQIRVLLMELEEAR 511
Cdd:pfam15921  699 MQLKSAQSELEQTR 712
PRK01156 PRK01156
chromosome segregation protein; Provisional
 65-499 5.32e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.74  E-value: 5.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     65 QERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQD---RNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYL 141
Cdd:PRK01156  151 RKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEklkSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNA 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    142 TEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKgNEILE 221
Cdd:PRK01156  231 MDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYK-NDIEN 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    222 LKCNLENKKEEVSRLEEQMNGLktsnEHLQKHVEDLLTKLKEAKE--QQASMEEKFHNELNAHIklsNLYKSAADDSEAK 299
Cdd:PRK01156  310 KKQILSNIDAEINKYHAIIKKL----SVLQKDYNDYIKKKSRYDDlnNQILELEGYEMDYNSYL---KSIESLKKKIEEY 382

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    300 SNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKemleKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Cdd:PRK01156  383 SKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISS----KVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVC 458

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    380 PTAAAVAKIvkpgmklTELYNAYVETQDQLLLEKLENKRINKYLDE-IVKEVEAKAPILKRQREEYERAQKAVASLSVKL 458
Cdd:PRK01156  459 GTTLGEEKS-------NHIINHYNEKKSRLEEKIREIEIEVKDIDEkIVDLKKRKEYLESEEINKSINEYNKIESARADL 531

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 1850342    459 EQAMKEIQRLQEDTDKANkqssvlERDNRRMEIQVKDLSQQ 499
Cdd:PRK01156  532 EDIKIKINELKDKHDKYE------EIKNRYKSLKLEDLDSK 566
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
29-217 5.69e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 5.69e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    29 LADQQSEIDGLKGRHEKFK-VESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEiaqdrnI 107
Cdd:COG4913  257 IRELAERYAAARERLAELEyLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELE------A 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   108 AIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLkesNTTKGELQLKLDELQASDVSVKYREKRLEQEK 187
Cdd:COG4913  331 QIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPL---PASAEEFAALRAEAAALLEALEEELEALEEAL 407

                        170       180       190
                 ....*....|....*....|....*....|
gi 1850342   188 ELLHSQNTWLNTELKTKTDELLALGREKGN 217
Cdd:COG4913  408 AEAEAALRDLRRELRELEAEIASLERRKSN 437
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 666-1138 6.85e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 48.28  E-value: 6.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     666 IEAKAALKQLQEIFENYKKEkaeNEKIQNEQLEKLQeqVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLheR 745
Cdd:pfam10174  188 AEAEMQLGHLEVLLDQKEKE---NIHLREELHRRNQ--LQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQML--K 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     746 NQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLS---EVRLSQQ----------RESLLAEQRGQ 812
Cdd:pfam10174  261 TNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQtklETLTNQNsdckqhievlKESLTAKEQRA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     813 NLLLTNLQTIQGILERSE------TETKQRLSSQIEKLEHEISHLKKKL---ENEVEQRHTLTRNLDVQLLDTKRQLDTE 883
Cdd:pfam10174  341 AILQTEVDALRLRLEEKEsflnkkTKQLQDLTEEKSTLAGEIRDLKDMLdvkERKINVLQKKIENLQEQLRDKDKQLAGL 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     884 TNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQpSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVE 963
Cdd:pfam10174  421 KERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDR-ERLEELESLKKENKDLKEKVSALQPELTEKESSLI 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     964 QYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEK--KLMEVEKEKQELQDdkrrAIESMEQQLSELKKTLS 1041
Cdd:pfam10174  500 DLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKahNAEEAVRTNPEIND----RIRLLEQEVARYKEESG 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1042 SVQNEVQ---EALQRASTALSN--------EQQARRDCQEQAKIAV-------EAQNKYERELMLH------AADVEALQ 1097
Cdd:pfam10174  576 KAQAEVErllGILREVENEKNDkdkkiaelESLTLRQMKEQNKKVAnikhgqqEMKKKGAQLLEEArrrednLADNSQQL 655

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 1850342    1098 AAKEQVSKMASVRQHLEETTQKAESQllecKASWEERERML 1138
Cdd:pfam10174  656 QLEELMGALEKTRQELDATKARLSST----QQSLAEKDGHL 692
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1491-1630 7.33e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 7.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1491 KSLESQVENLQ---KTLSEKETEARNLQEQTVQLQselsRLRQDLQDRTTQEEQLRQQiteKEEKTRKAIVAAKSKIAHL 1567
Cdd:COG4913  221 PDTFEAADALVehfDDLERAHEALEDAREQIELLE----PIRELAERYAAARERLAEL---EYLRAALRLWFAQRRLELL 293

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1850342  1568 AGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEG----RISRLERELREHQERHLEQRDE 1630
Cdd:COG4913  294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGnggdRLEQLEREIERLERELEERERR 360
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1346-1565 9.47e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.13  E-value: 9.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1346 QKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQ 1425
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1426 EK-------------------VKTITQVKKIGRRYKTQYEELKAQQDKVmetsaqssgdhqeqhvsVQEMQELKETLNQA 1486
Cdd:COG3883   97 RSggsvsyldvllgsesfsdfLDRLSALSKIADADADLLEELKADKAEL-----------------EAKKAELEAKLAEL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1850342  1487 ETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIA 1565
Cdd:COG3883  160 EALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1474-1648 1.03e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1474 QEMQELKETLNQAETKskslESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQ--DLQDRTTQEEQLRQQITEKEE 1551
Cdd:COG4717   71 KELKELEEELKEAEEK----EEEYAELQEELEELEEELEELEAELEELREELEKLEKllQLLPLYQELEALEAELAELPE 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1552 KTRKAivaaKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDV----RITALKSQYE---GRISRLERELREHQERH 1624
Cdd:COG4717  147 RLEEL----EERLEELRELEEELEELEAELAELQEELEELLEQLSLateeELQDLAEELEelqQRLAELEEELEEAQEEL 222

                        170       180
                 ....*....|....*....|....
gi 1850342  1625 LEQRDEPQEPSNKVPEQQRQITLK 1648
Cdd:COG4717  223 EELEEELEQLENELEAAALEERLK 246
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1444-1619 1.05e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.61  E-value: 1.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1444 QYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELK-----ETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQT 1518
Cdd:PRK05771   44 RLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEI 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1519 VQLQ------SELSRLRQ-------------DLQDRTTQEEQLRQQITEKEEKTRKAIVaakskiahLAGVKDQLTKENE 1579
Cdd:PRK05771  124 ERLEpwgnfdLDLSLLLGfkyvsvfvgtvpeDKLEELKLESDVENVEYISTDKGYVYVV--------VVVLKELSDEVEE 195

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1850342   1580 ELKQrngaLDQQKDELDVRITA--LKSQYEGRISRLERELRE 1619
Cdd:PRK05771  196 ELKK----LGFERLELEEEGTPseLIREIKEELEEIEKERES 233
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1-274 1.07e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      1 MAAVLQQVLERTELNKLPKSVQNKLEKFLAdQQSEIDGLKGRHEKFKveseqqyfEIEKRLS-HSQERLVNETRECQSLR 79
Cdd:PRK03918  461 LKRIEKELKEIEEKERKLRKELRELEKVLK-KESELIKLKELAEQLK--------ELEEKLKkYNLEELEKKAEEYEKLK 531

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     80 LELEKLNNQLKALTEKNKELEIAQDRNIAIQSQftrtKEELEAEKRDLIRTNERLSQE-LEYLTEDVKRLNEKLKESNTT 158
Cdd:PRK03918  532 EKLIKLKGEIKSLKKELEKLEELKKKLAELEKK----LDELEEELAELLKELEELGFEsVEELEERLKELEPFYNEYLEL 607

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    159 KG---ELQLKLDELQASDVSVKYREKRLEQEKellhsqntwlnTELKTKTDELLALGREKGNEilelkcNLENKKEEVSR 235
Cdd:PRK03918  608 KDaekELEREEKELKKLEEELDKAFEELAETE-----------KRLEELRKELEELEKKYSEE------EYEELREEYLE 670

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1850342    236 LEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEK 274
Cdd:PRK03918  671 LSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKA 709
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
23-511 1.14e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.73  E-value: 1.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     23 NKLEKFLADQQSEIDglkgRHEKFKVESEQQYFEIEKRLSHSQERlvnetrecqslRLELEKLNNQLKALTEKNKELEia 102
Cdd:PRK02224  209 NGLESELAELDEEIE----RYEEQREQARETRDEADEVLEEHEER-----------REELETLEAEIEDLRETIAETE-- 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    103 qdrniaiqsqftRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKR 182
Cdd:PRK02224  272 ------------REREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQA 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    183 LEQEKELLHSQNTWL---NTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLT 259
Cdd:PRK02224  340 HNEEAESLREDADDLeerAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELRE 419

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    260 KLKEAKEQQASMEEKFHNELNAhiklsnLYKSAADDSEAKSNELTRAVEElHKLLKEAGEANKAIQDHLLEVEQSKDQME 339
Cdd:PRK02224  420 ERDELREREAELEATLRTARER------VEEAEALLEAGKCPECGQPVEG-SPHVETIEEDRERVEELEAELEDLEEEVE 492

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    340 KemlekigrLEKELENANDLLSATKRKGAILSEEELAAmsptaaavakivkpgmKLTELYNAYVETQDqlllEKLENKRI 419
Cdd:PRK02224  493 E--------VEERLERAEDLVEAEDRIERLEERREDLE----------------ELIAERRETIEEKR----ERAEELRE 544

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    420 NKylDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQE----DTDKANKQSSVLERDNRRMEIQ--- 492
Cdd:PRK02224  545 RA--AELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERirtlLAAIADAEDEIERLREKREALAeln 622

                         490       500
                  ....*....|....*....|....*
gi 1850342    493 ------VKDLSQQIRVLLMELEEAR 511
Cdd:PRK02224  623 derrerLAEKRERKRELEAEFDEAR 647
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
667-886 1.15e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   667 EAKAALKQLQEIFENYK--KEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQ--------LDFASKRYEMLQDNVEGYR 736
Cdd:COG4913  222 DTFEAADALVEHFDDLEraHEALEDAREQIELLEPIRELAERYAAARERLAELeylraalrLWFAQRRLELLEAELEELR 301

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   737 REITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKlavaeiRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNL-- 814
Cdd:COG4913  302 AELARLEAELERLEARLDALREELDELEAQIRGNGGD------RLEQLEREIERLERELEERERRRARLEALLAALGLpl 375

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   815 ------LLTNLQTIQGILERSETETKQ------RLSSQIEKLEHEISHLKKKLEnEVEQRHTltrNLDVQLLDTKRQLDT 882
Cdd:COG4913  376 pasaeeFAALRAEAAALLEALEEELEAleealaEAEAALRDLRRELRELEAEIA-SLERRKS---NIPARLLALRDALAE 451


                 ....
gi 1850342   883 ETNL 886
Cdd:COG4913  452 ALGL 455
PRK11281 PRK11281
mechanosensitive channel MscK;
1280-1527 1.16e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1280 REEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKS----GMLQAEKKLLE--EDVKRWKAR----NQHLVSQQKDP 1349
Cdd:PRK11281   79 KEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETlstlSLRQLESRLAQtlDQLQNAQNDlaeyNSQLVSLQTQP 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1350 dtEEYRKLLSEkevHTKRIQQLT---------------EEIGRLKAEIARSNASLTNNQNLIQSlkedlNKVRTEKETIQ 1414
Cdd:PRK11281  159 --ERAQAALYA---NSQRLQQIRnllkggkvggkalrpSQRVLLQAEQALLNAQNDLQRKSLEG-----NTQLQDLLQKQ 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1415 KDL-DAKIIDIQEKVKTITQVkkIGRRYKTQYEELKAQQDkvmetSAQSSGDHQEQHVSVQEMQ---ELKETLNQAETKS 1490
Cdd:PRK11281  229 RDYlTARIQRLEHQLQLLQEA--INSKRLTLSEKTVQEAQ-----SQDEAARIQANPLVAQELEinlQLSQRLLKATEKL 301

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1850342   1491 KSL-------ESQVENLQKTlseketeARNLQEQTVQLQSE--LSR 1527
Cdd:PRK11281  302 NTLtqqnlrvKNWLDRLTQS-------ERNIKEQISVLKGSllLSR 340
COG5022 COG5022
Myosin heavy chain [General function prediction only];
51-521 1.30e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 47.38  E-value: 1.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    51 EQQYFEIEKRLSHSQERlvNETRECQSLRLELEK-LNNQLKALTEKNKELEIaqdRNIAIQSQFTRTkeeLEAEKRDLIR 129
Cdd:COG5022  793 WRLFIKLQPLLSLLGSR--KEYRSYLACIIKLQKtIKREKKLRETEEVEFSL---KAEVLIQKFGRS---LKAKKRFSLL 864

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   130 TNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAsdvsvKYREKRLEQEKELLhsqntwLNTELKTKTDELL 209
Cdd:COG5022  865 KKETIYLQSAQRVELAERQLQELKIDVKSISSLKLVNLELES-----EIIELKKSLSSDLI------ENLEFKTELIARL 933

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   210 ALGREKGNEILELKCNLEnKKEEVSRLEEQMNGLKTSNEHLqkhvEDLLTKLKEAKEQQASMEEKFHN---ELNAHIKLs 286
Cdd:COG5022  934 KKLLNNIDLEEGPSIEYV-KLPELNKLHEVESKLKETSEEY----EDLLKKSTILVREGNKANSELKNfkkELAELSKQ- 1007

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   287 nlyKSAADDSEAKSNELTRAVEELH---KLLKEAGEA-------NKAIQDHLLEVEQSKDQME-----KEMLEKIGRLEK 351
Cdd:COG5022 1008 ---YGALQESTKQLKELPVEVAELQsasKIISSESTElsilkplQKLKGLLLLENNQLQARYKalklrRENSLLDDKQLY 1084

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   352 ELENANDLLSATKRKGAILSEEELAAMSP-TAAAVAKIVKPG-----MKLTELYNAYVETQDQLLLEKLENKRINKYLDE 425
Cdd:COG5022 1085 QLESTENLLKTINVKDLEVTNRNLVKPANvLQFIVAQMIKLNllqeiSKFLSQLVNTLEPVFQKLSVLQLELDGLFWEAN 1164

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   426 IVKEVEAKAPILKRQREEYEraqkaVASLSVKLEQAMKEIQRLQEDTDKANKQssvlERDNRRMEIQVKDLSQQIRVLLM 505
Cdd:COG5022 1165 LEALPSPPPFAALSEKRLYQ-----SALYDEKSKLSSSEVNDLKNELIALFSK----IFSGWPRGDKLKKLISEGWVPTE 1235

                        490
                 ....*....|....*.
gi 1850342   506 ELEEARGNHVIRDEEV 521
Cdd:COG5022 1236 YSTSLKGFNNLNKKFD 1251
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1084-1627 1.38e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1084 RELMLHAADV-EALQAAKEQVSKMASVRQHLEETTQKAEsQLLECKASWEERERmLKDEVSKCV-----CRCEDLEKQNR 1157
Cdd:COG4913  214 REYMLEEPDTfEAADALVEHFDDLERAHEALEDAREQIE-LLEPIRELAERYAA-ARERLAELEylraaLRLWFAQRRLE 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1158 LLHDQIEKLSDKvvasvKEGVQGPLNVSLSEEGKSQEQILEILRFIRR---------EKEIAETRFEVAQVE--SLRYRQ 1226
Cdd:COG4913  292 LLEAELEELRAE-----LARLEAELERLEARLDALREELDELEAQIRGnggdrleqlEREIERLERELEERErrRARLEA 366

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1227 RVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNkmLREEKERLEQDLQQMQAkvRKLELDiLP 1306
Cdd:COG4913  367 LLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRD--LRRELRELEAEIASLER--RKSNIP-AR 441

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1307 LQEANAELSEKSGMLQAEKKLLEE--DVK----RWKA------RNQH---LVSQQKDPD-TEEYRKLLSEKEVHTKRIQQ 1370
Cdd:COG4913  442 LLALRDALAEALGLDEAELPFVGEliEVRpeeeRWRGaiervlGGFAltlLVPPEHYAAaLRWVNRLHLRGRLVYERVRT 521

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1371 LTEEIGRLKA---------EIARS------NASLTNNQNLIQ--SLkEDLNKVR---TEKETIQKDLDAKIIDIQEKVKT 1430
Cdd:COG4913  522 GLPDPERPRLdpdslagklDFKPHpfrawlEAELGRRFDYVCvdSP-EELRRHPraiTRAGQVKGNGTRHEKDDRRRIRS 600

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1431 ITQvkkIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQ------AETKSKSLESQVENLQKTL 1504
Cdd:COG4913  601 RYV---LGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswDEIDVASAEREIAELEAEL 677

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1505 SEKET---EARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAivaaksKIAHLAGVKDQLTKENEEL 1581
Cdd:COG4913  678 ERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDEL------QDRLEAAEDLARLELRALL 751

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|....*...
gi 1850342  1582 KQRNGALDQQKDELDVR--ITALKSQYEGRISRLERELREHQERHLEQ 1627
Cdd:COG4913  752 EERFAAALGDAVERELRenLEERIDALRARLNRAEEELERAMRAFNRE 799
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
851-1339 1.47e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   851 LKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQpsn 930
Cdd:COG4717   47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK--- 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   931 KEDVDDLVSQLRQTEEQVNDLKERLktstsnveqyqamvtsleESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLME 1010
Cdd:COG4717  124 LLQLLPLYQELEALEAELAELPERL------------------EELEERLEELRELEEELEELEAELAELQEELEELLEQ 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1011 VEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVqEALQRASTALSNEQQARRDCQEQAK-----------IAVEAQ 1079
Cdd:COG4717  186 LSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL-EELEEELEQLENELEAAALEERLKEarlllliaaalLALLGL 264

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1080 NKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERmlkdevskcvcrcEDLEKQNRLL 1159
Cdd:COG4717  265 GGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEEL-------------EELLAALGLP 331

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1160 HDQIEKLSDKVVASVKEGVQgplnvSLSEEGKSQEQileiLRFIRREKEIAETrFEVAQVESL-RYRQRVELLERELQEL 1238
Cdd:COG4717  332 PDLSPEELLELLDRIEELQE-----LLREAEELEEE----LQLEELEQEIAAL-LAEAGVEDEeELRAALEQAEEYQELK 401

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1239 QDSLNAERekvQVTAKTMAQHEELMKKTETMnvVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLqEANAELSEKS 1318
Cdd:COG4717  402 EELEELEE---QLEELLGELEELLEALDEEE--LEEELEELEEELEELEEELEELREELAELEAELEQL-EEDGELAELL 475

                        490       500
                 ....*....|....*....|.
gi 1850342  1319 GMLQAEKKLLEEDVKRWKARN 1339
Cdd:COG4717  476 QELEELKAELRELAEEWAALK 496
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1475-1696 1.64e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.36  E-value: 1.64e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1475 EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEK----- 1549
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaraly 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1550 -------------------------------EEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDvr 1598
Cdd:COG3883   97 rsggsvsyldvllgsesfsdfldrlsalskiADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE-- 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1599 itALKSQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTP 1678
Cdd:COG3883  175 --AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAA 252

                        250
                 ....*....|....*...
gi 1850342  1679 SKVTAAAMAGNKSTPRAS 1696
Cdd:COG3883  253 GAAGAAAGSAGAAGAAAG 270
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 3-596 1.64e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 47.27  E-value: 1.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342       3 AVLQQVLERTELNKLPKSVQnKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLEL 82
Cdd:pfam02463  305 LERRKVDDEEKLKESEKEKK-KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      83 EKLNNQLK----ALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTT 158
Cdd:pfam02463  384 ERLSSAAKlkeeELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKD 463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     159 KGELQLKLDELQaSDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEE 238
Cdd:pfam02463  464 ELELKKSEDLLK-ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYK 542

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     239 QMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLS----------------NLYKSAADDSEAKSNE 302
Cdd:pfam02463  543 VAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPlksiavleidpilnlaQLDKATLEADEDDKRA 622

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     303 LTRAVEELHKLLKEAGEANKAIQDHLLE-VEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPT 381
Cdd:pfam02463  623 KVVEGILKDTELTKLKESAKAKESGLRKgVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIK 702

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     382 AAAVAKIVKPGMKLTELYNayVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQA 461
Cdd:pfam02463  703 KKEQREKEELKKLKLEAEE--LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEER 780

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     462 MKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYR 541
Cdd:pfam02463  781 EKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLE 860

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1850342     542 NIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKS 596
Cdd:pfam02463  861 EEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEK 915
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 49-273 1.73e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    49 ESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEiaqdrniaiqsqftRTKEELEAEKRDLI 128
Cdd:COG4942   24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE--------------QELAALEAELAELE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   129 RTNERLSQELEYLTEDVKRLNEKL-KESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLhsqntwlnTELKTKTDE 207
Cdd:COG4942   90 KEIAELRAELEAQKEELAELLRALyRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQA--------EELRADLAE 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1850342   208 LLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEE 273
Cdd:COG4942  162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
PTZ00121 PTZ00121
MAEBL; Provisional
 118-996 2.00e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 2.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    118 EELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYRE-KRLEQEKELLHSQNTw 196
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDaKKAEAARKAEEVRKA- 1190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    197 lnTELKTKTDELLALGREKGNEilelkcnlENKKEEVSRLEEQMNGLKTsnehlqKHVEDLLTKLKEAKEQqasmEEKFH 276
Cdd:PTZ00121 1191 --EELRKAEDARKAEAARKAEE--------ERKAEEARKAEDAKKAEAV------KKAEEAKKDAEEAKKA----EEERN 1250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    277 NELNAHIKLSNLYKSAADDSEAKSNElTRAVEELHKL--LKEAGEANKAiqDHLLEVEQSKDQMEKEmlEKIGRLEKELE 354
Cdd:PTZ00121 1251 NEEIRKFEEARMAHFARRQAAIKAEE-ARKADELKKAeeKKKADEAKKA--EEKKKADEAKKKAEEA--KKADEAKKKAE 1325

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    355 NANDLLSATKRKG--AILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEA 432
Cdd:PTZ00121 1326 EAKKKADAAKKKAeeAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    433 KAPILKRQREEYERAQ--KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEA 510
Cdd:PTZ00121 1406 KADELKKAAAAKKKADeaKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA 1485

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    511 RGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQrllvaLRELGETREREEQETTSSKITELQLKLESALTEL 590
Cdd:PTZ00121 1486 DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADE-----AKKAEEAKKADEAKKAEEKKKADELKKAEELKKA 1560

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    591 EQLRKSRQhqmqlvdsiVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQtvstpapvpviESTEAIEAKA 670
Cdd:PTZ00121 1561 EEKKKAEE---------AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAE-----------EAKKAEEAKI 1620

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    671 ALKQLQEIFENYK-----KEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQldfASKRYEMLQDNVEGYRREitslHER 745
Cdd:PTZ00121 1621 KAEELKKAEEEKKkveqlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE---DKKKAEEAKKAEEDEKKA----AEA 1693

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    746 NQKLTATTQKQEQIINTMTQDLRGANE---KLAVAEIRAENLKKEKEMLKLSEVRLSQQRESllaEQRGQNLLLTNLQTI 822
Cdd:PTZ00121 1694 LKKEAEEAKKAEELKKKEAEEKKKAEElkkAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE---KKKIAHLKKEEEKKA 1770

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    823 QGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIA 902
Cdd:PTZ00121 1771 EEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFE 1850

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    903 TLKRHLSNMEVQvaSQSSQRTGKGQPSNKEDVDDLVSQLRQTEE-QVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQ 981
Cdd:PTZ00121 1851 KHKFNKNNENGE--DGNKEADFNKEKDLKEDDEEEIEEADEIEKiDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRD 1928

                         890
                  ....*....|....*
gi 1850342    982 VTEEVRKNIEVRLKE 996
Cdd:PTZ00121 1929 AEETREEIIKISKKD 1943
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 13-1579 2.00e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 46.97  E-value: 2.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      13 ELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQ----QYF-EIEKRLSHSQERLVNETREcqslrlELEK-LN 86
Cdd:TIGR01612  956 ESNLIEKSYKDKFDNTLIDKINELDKAFKDASLNDYEAKNneliKYFnDLKANLGKNKENMLYHQFD------EKEKaTN 1029

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      87 NQLKALTEKNKELEiaqDRNIAIQSQFTRTKEELEAE-KRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTT---KGEL 162
Cdd:TIGR01612 1030 DIEQKIEDANKNIP---NIEIAIHTSIYNIIDEIEKEiGKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDdfgKEEN 1106

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     163 QLKLDELQASDVSVKYREKRLEQEKELLhsqntwlnTELKTKTDELLALGREKGNEiLELKCNLENKKEEVSRLEEQMNG 242
Cdd:TIGR01612 1107 IKYADEINKIKDDIKNLDQKIDHHIKAL--------EEIKKKSENYIDEIKAQIND-LEDVADKAISNDDPEEIEKKIEN 1177

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     243 LKTS---NEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGE 319
Cdd:TIGR01612 1178 IVTKidkKKNIYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKE 1257

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     320 ANKAIQdhlleveqskDQMEKEMLEKigrleKELENANdLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELY 399
Cdd:TIGR01612 1258 KSPEIE----------NEMGIEMDIK-----AEMETFN-ISHDDDKDHHIISKKHDENISDIREKSLKIIEDFSEESDIN 1321

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     400 NAYVETQDQLLLEKLENKRINKYLDEI-----------VKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRL 468
Cdd:TIGR01612 1322 DIKKELQKNLLDAQKHNSDINLYLNEIaniynilklnkIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINL 1401

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     469 QE------------DTDKANKQSSVL-------ERDNRRMEIQVKDLSQQIRVLLMELEEA--RGNHVIRDE-------- 519
Cdd:TIGR01612 1402 EEckskiestlddkDIDECIKKIKELknhilseESNIDTYFKNADENNENVLLLFKNIEMAdnKSQHILKIKkdnatndh 1481

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     520 --------EVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALR---ELGETREREEQETTSSKI------TELQLK 582
Cdd:TIGR01612 1482 dfninelkEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLNkysALAIKNKFAKTKKDSEIIikeikdAHKKFI 1561

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     583 LESALTElEQLRKSRQHQMQLVDSIVRQRDmyrillSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIES 662
Cdd:TIGR01612 1562 LEAEKSE-QKIKEIKKEKFRIEDDAAKNDK------SNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESIEKKIS 1634

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     663 TEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMlqdnveGYRREITSL 742
Cdd:TIGR01612 1635 SFSIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEI------GIIEKIKEI 1708

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     743 HERNQ-KLTATTQKQEQIINTM-----TQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRL----SQQRESLLAEQ--- 809
Cdd:TIGR01612 1709 AIANKeEIESIKELIEPTIENLissfnTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAgcleTVSKEPITYDEikn 1788

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     810 ---RGQNLLLTNLQtiqgilerSETETKQRLSS-QIEKLEHEISHLKKKLENEVeqrhtltrnldvqlldtkrqlDTETN 885
Cdd:TIGR01612 1789 triNAQNEFLKIIE--------IEKKSKSYLDDiEAKEFDRIINHFKKKLDHVN---------------------DKFTK 1839

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     886 LHLNTKELLKNAQKEIATLKRH-----LSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKErlktSTS 960
Cdd:TIGR01612 1840 EYSKINEGFDDISKSIENVKNStdenlLFDILNKTKDAYAGIIGKKYYSYKDEAEKIFINISKLANSINIQIQ----NNS 1915

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     961 NVEQYQAMVTSLEESLNKEKQVT------EEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQE---LQDDKRRAIESMeQ 1031
Cdd:TIGR01612 1916 GIDLFDNINIAILSSLDSEKEDTlkfipsPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQDtlnIIFENQQLYEKI-Q 1994

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1032 QLSELKKTLSSVQ-------NEVQEALQRAS-----TALSNEQQARRDCQEQAKIAvEAQNKYERELMLHAADVEaLQAA 1099
Cdd:TIGR01612 1995 ASNELKDTLSDLKykkekilNDVKLLLHKFDelnklSCDSQNYDTILELSKQDKIK-EKIDNYEKEKEKFGIDFD-VKAM 2072

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1100 KEQVSKMASVRQHLEETTQKAESQLLEckaSWEERERMLKDEvskcvcrcEDLEKQNRLLHDQIEKLSDKVVAsvKEGVQ 1179
Cdd:TIGR01612 2073 EEKFDNDIKDIEKFENNYKHSEKDNHD---FSEEKDNIIQSK--------KKLKELTEAFNTEIKIIEDKIIE--KNDLI 2139

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1180 GPLN-----------VSLSEEGKSqeQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELqelqdSLNAEREK 1248
Cdd:TIGR01612 2140 DKLIemrkecllfsyATLVETLKS--KVINHSEFITSAAKFSKDFFEFIEDISDSLNDDIDALQIKY-----NLNQTKKH 2212

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1249 V-QVTAKTMAQHEELMKKTEtmnvvmETNKMLREEKERLEQDLQQMQAKVrkLELDILPLQEANAELsEKSgmLQAEKKL 1327
Cdd:TIGR01612 2213 MiSILADATKDHNNLIEKEK------EATKIINNLTELFTIDFNNADADI--LHNNKIQIIYFNSEL-HKS--IESIKKL 2281

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1328 LEEdVKRWKARNQHL-------VSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLtnNQNLIQSLK 1400
Cdd:TIGR01612 2282 YKK-INAFKLLNISHinekyfdISKEFDNIIQLQKHKLTENLNDLKEIDQYISDKKNIFLHALNENTNF--NFNALKEIY 2358

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1401 EDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQV-KKIGR--RYKTQYEelkaQQDKVMETSAQssgDHQEQHVS----- 1472
Cdd:TIGR01612 2359 DDIINRENKADEIENINNKENENIMQYIDTITKLtEKIQDilIFVTTYE----NDNNIIKQHIQ---DNDENDVSkikdn 2431

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1473 ----VQEMQELKETLNQAETKSKSlESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQD-RTTQEEQLRQQIT 1547
Cdd:TIGR01612 2432 lkktIQSFQEILNKIDEIKAQFYG-GNNINNIIITISQNANDVKNHFSKDLTIENELIQIQKRLEDiKNAAHEIRSEQIT 2510

                         1690      1700      1710
                   ....*....|....*....|....*....|..
gi 1850342    1548 EKEEKTRKAIVAAKSKIAHlAGVKDQLTKENE 1579
Cdd:TIGR01612 2511 KYTNAIHNHIEEQFKKIEN-NSNKDEVYKINE 2541
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 892-1596 2.06e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.76  E-value: 2.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     892 ELLKNAQKEIATLKRHLSNMEVQVASQSSQRtgkgqpsnKEDVDDLVSQLRQTEEQVND----LKERLKTSTSNVEQYQA 967
Cdd:pfam12128  251 NTLESAELRLSHLHFGYKSDETLIASRQEER--------QETSAELNQLLRTLDDQWKEkrdeLNGELSAADAAVAKDRS 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     968 MVTSLEESLNKEKQVTEEVRKNIEVRLKEsaeFQTQLEkklmEVEKEKQELQDdkrrAIESMEQQLSELKKTLSSVQNEV 1047
Cdd:pfam12128  323 ELEALEDQHGAFLDADIETAAADQEQLPS---WQSELE----NLEERLKALTG----KHQDVTAKYNRRRSKIKEQNNRD 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1048 qeaLQRASTALSNEQQARRDCQEQAKIAVEAQNKYERElMLHAADVEALQAAKEQVSKMASVRQHLEETTqkAESQLLEC 1127
Cdd:pfam12128  392 ---IAGIKDKLAKIREARDRQLAVAEDDLQALESELRE-QLEAGKLEFNEEEYRLKSRLGELKLRLNQAT--ATPELLLQ 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1128 KASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVvasvkegvqGPLNVSLSEEGKSQEQILE--------I 1199
Cdd:pfam12128  466 LENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEAL---------RQASRRLEERQSALDELELqlfpqagtL 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1200 LRFIRREKEI-AETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQ-VTAKTMAQHEELMKktETMNVVMETNK 1277
Cdd:pfam12128  537 LHFLRKEAPDwEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKrIDVPEWAASEEELR--ERLDKAEEALQ 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1278 MLREEKERLEQDLQQMQAKV----RKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQhlvsqqkdpdtEE 1353
Cdd:pfam12128  615 SAREKQAAAEEQLVQANGELekasREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSAN-----------ER 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1354 YRKLLSEKEVHTKRIQQLTEEIGRLKAEIarSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKvktitq 1433
Cdd:pfam12128  684 LNSLEAQLKQLDKKHQAWLEEQKEQKREA--RTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETW------ 755

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1434 vkkigrrYKTQYEELKAQQDKVMETSaqssgdhqeqhvsvQEMQELKETLNQAETKSKSLESQVENLQKTLSEketEARN 1513
Cdd:pfam12128  756 -------YKRDLASLGVDPDVIAKLK--------------REIRTLERKIERIAVRRQEVLRYFDWYQETWLQ---RRPR 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1514 LQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAA-------KSKIAHLAGVKDQLTKENEELK--QR 1584
Cdd:pfam12128  812 LATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLsenlrglRCEMSKLATLKEDANSEQAQGSigER 891

                          730
                   ....*....|..
gi 1850342    1585 NGALDQQKDELD 1596
Cdd:pfam12128  892 LAQLEDLKLKRD 903
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 673-1564 2.12e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 46.97  E-value: 2.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     673 KQLQEIFENYK-KEKAENEKI-----QNEQLEKLQEQVTDLRSQ-NTKIS---TQLDFASKRYEMLQDNVEGYR------ 736
Cdd:TIGR01612  751 KDLNKILEDFKnKEKELSNKIndyakEKDELNKYKSKISEIKNHyNDQINidnIKDEDAKQNYDKSKEYIKTISikedei 830

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     737 -REITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLA------VAEIRAENLKKEKEMLKLSEVRLSQQRESLlaEQ 809
Cdd:TIGR01612  831 fKIINEMKFMKDDFLNKVDKFINFENNCKEKIDSEHEQFAeltnkiKAEISDDKLNDYEKKFNDSKSLINEINKSI--EE 908

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     810 RGQNLllTNLQTIQGILE--RSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTE-TNL 886
Cdd:TIGR01612  909 EYQNI--NTLKKVDEYIKicENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKAfKDA 986

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     887 HLNTKELLKNAqkeiatLKRHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNV-EQY 965
Cdd:TIGR01612  987 SLNDYEAKNNE------LIKYFNDLKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIiDEI 1060

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     966 QAMVTSLEESLNKEkqVTEEVRKNIEV--RLKESAE---FQTQLEKKLMEVEKEKQELQDDkrraIESMEQQ-------L 1033
Cdd:TIGR01612 1061 EKEIGKNIELLNKE--ILEEAEINITNfnEIKEKLKhynFDDFGKEENIKYADEINKIKDD----IKNLDQKidhhikaL 1134

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1034 SELKKTLSSVQNEVQEALQR----ASTALSNEQQARRDCQEQAKIAVEAQNKY----ERELMLHAADVEALQAAKEQVSK 1105
Cdd:TIGR01612 1135 EEIKKKSENYIDEIKAQINDledvADKAISNDDPEEIEKKIENIVTKIDKKKNiydeIKKLLNEIAEIEKDKTSLEEVKG 1214

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1106 M-ASVRQHL--------EETTQKAESQLLECKASWEERERMLKD--EVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASV 1174
Cdd:TIGR01612 1215 InLSYGKNLgklflekiDEEKKKSEHMIKAMEAYIEDLDEIKEKspEIENEMGIEMDIKAEMETFNISHDDDKDHHIISK 1294

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1175 KEgvqgplNVSLSEegkSQEQILEILRFIRREKEIAETRFEVAQ--VESLRYRQRVELLERELQELQDSLNAER-----E 1247
Cdd:TIGR01612 1295 KH------DENISD---IREKSLKIIEDFSEESDINDIKKELQKnlLDAQKHNSDINLYLNEIANIYNILKLNKikkiiD 1365

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1248 KVQVTAKTMAQHEELMK----KTETMNVVMETNKMLREEKERLE-----QDLQQMQAKVRKLELDILPLQEANAELSEKS 1318
Cdd:TIGR01612 1366 EVKEYTKEIEENNKNIKdeldKSEKLIKKIKDDINLEECKSKIEstlddKDIDECIKKIKELKNHILSEESNIDTYFKNA 1445

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1319 GMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSE-------------------------KEVHTKRIQQLTE 1373
Cdd:TIGR01612 1446 DENNENVLLLFKNIEMADNKSQHILKIKKDNATNDHDFNINElkehidkskgckdeadknakaieknKELFEQYKKDVTE 1525

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1374 EIGRLKAEIARSNASLTNNQN--LIQSLKEDLNKVRTEKETIQ---KDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEEL 1448
Cdd:TIGR01612 1526 LLNKYSALAIKNKFAKTKKDSeiIIKEIKDAHKKFILEAEKSEqkiKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENF 1605

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1449 KAQQDKVMETSAQSSGDHQEQHVSVQEMQELkeTLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQL---QSEL 1525
Cdd:TIGR01612 1606 ENKFLKISDIKKKINDCLKETESIEKKISSF--SIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELdelDSEI 1683

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|
gi 1850342    1526 SRLRQDL-QDRTTQEEQLRQQITEKEEKTRKAIVAAKSKI 1564
Cdd:TIGR01612 1684 EKIEIDVdQHKKNYEIGIIEKIKEIAIANKEEIESIKELI 1723
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1001-1627 2.14e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.65  E-value: 2.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1001 QTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEaLQRASTALSNEQqaRRDCQEQAKIAVEAQN 1080
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQE-MQMERDAMADIR--RRESQSQEDLRNQLQN 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1081 --------KYERELMLHAADVEALQAAKEQVSK---MASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVcrc 1149
Cdd:pfam15921  150 tvheleaaKCLKEDMLEDSNTQIEQLRKMMLSHegvLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKIL--- 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1150 EDLEKQNRLLHDQIEKLSDKVVAsvkegvqgplnvsLSEEGKSQEQILEILRFIRREKEIAETRFEVAQveslryrqrVE 1229
Cdd:pfam15921  227 RELDTEISYLKGRIFPVEDQLEA-------------LKSESQNKIELLLQQHQDRIEQLISEHEVEITG---------LT 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1230 LLERELQELQDSLNAEREKVQVTAKTmaQHEELMKK-TETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQ 1308
Cdd:pfam15921  285 EKASSARSQANSIQSQLEIIQEQARN--QNSMYMRQlSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEAR 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1309 EANAELSEKSGMLQAE-KKLLEEDVKRWKARNQHLVSQQK--DPDT------EEYRKLLSEKEVHTKRIQQLTE------ 1373
Cdd:pfam15921  363 TERDQFSQESGNLDDQlQKLLADLHKREKELSLEKEQNKRlwDRDTgnsitiDHLRRELDDRNMEVQRLEALLKamksec 442

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1374 --EIGRLKAEIARSNASLTNNQNL---IQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEEL 1448
Cdd:pfam15921  443 qgQMERQMAAIQGKNESLEKVSSLtaqLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKL 522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1449 KAQQD-KVMETSAQSSGDHQEQHVSVqEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSR 1527
Cdd:pfam15921  523 RSRVDlKLQELQHLKNEGDHLRNVQT-ECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIND 601

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1528 LRQDLQD-------RTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVK---DQLTKENEELKQRNGALDQQKDELDV 1597
Cdd:pfam15921  602 RRLELQEfkilkdkKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKqerDQLLNEVKTSRNELNSLSEDYEVLKR 681

                          650       660       670
                   ....*....|....*....|....*....|
gi 1850342    1598 RITALKSQYEGRISRLERELREHQErHLEQ 1627
Cdd:pfam15921  682 NFRNKSEEMETTTNKLKMQLKSAQS-ELEQ 710
PRK01156 PRK01156
chromosome segregation protein; Provisional
 980-1623 2.14e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.82  E-value: 2.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    980 KQVTEEVRKNI-----EVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRaIESMEQQLSELKKTLSSVQ------NEVQ 1048
Cdd:PRK01156  111 DDTTKYIEKNIlgiskDVFLNSIFVGQGEMDSLISGDPAQRKKILDEILE-INSLERNYDKLKDVIDMLRaeisniDYLE 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1049 EALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQL---- 1124
Cdd:PRK01156  190 EKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLsmel 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1125 ---LECKASWEERERMLKDEVSKCVCRCEDLEKqnrlLHDQIEKLSDkvvasVKEGVQGPLNVSLSEEGKsqeqiLEILR 1201
Cdd:PRK01156  270 eknNYYKELEERHMKIINDPVYKNRNYINDYFK----YKNDIENKKQ-----ILSNIDAEINKYHAIIKK-----LSVLQ 335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1202 FIRREKEIAETRFEVAQVESLRYRQRvELLERELQELQDSLNAEREKVQVTAKTMAQheelmKKTETMNVVMETNKMLRE 1281
Cdd:PRK01156  336 KDYNDYIKKKSRYDDLNNQILELEGY-EMDYNSYLKSIESLKKKIEEYSKNIERMSA-----FISEILKIQEIDPDAIKK 409

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLV---SQQKDPDTEEYRKLL 1358
Cdd:PRK01156  410 ELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSNHIInhyNEKKSRLEEKIREIE 489

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1359 SE-KEVHTKRIQQLTEEIGRLKAEIARSNASltnnQNLIQSLKEDLNKVRTEKETIqKDLDAKIIDIQEKVKTITQvkKI 1437
Cdd:PRK01156  490 IEvKDIDEKIVDLKKRKEYLESEEINKSINE----YNKIESARADLEDIKIKINEL-KDKHDKYEEIKNRYKSLKL--ED 562

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1438 GRRYKTQYEELKAQQDKVMETSAQSSGDhqeqhvsvqemqELKETLNQAETKSKSLESQVENLQ----KTLSEKETEARN 1513
Cdd:PRK01156  563 LDSKRTSWLNALAVISLIDIETNRSRSN------------EIKKQLNDLESRLQEIEIGFPDDKsyidKSIREIENEANN 630

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1514 LQEQtvqlqselsrlRQDLQDRTTQEEQLRQQItekeEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKD 1593
Cdd:PRK01156  631 LNNK-----------YNEIQENKILIEKLRGKI----DNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKA 695

                         650       660       670
                  ....*....|....*....|....*....|
gi 1850342   1594 ELdVRITALKSQYEGRISRLERELREHQER 1623
Cdd:PRK01156  696 NR-ARLESTIEILRTRINELSDRINDINET 724
46 PHA02562
endonuclease subunit; Provisional
 837-1049 2.46e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.16  E-value: 2.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    837 LSSQIEKLEHEISHLKKKLEneveqrhTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVA 916
Cdd:PHA02562  179 LNQQIQTLDMKIDHIQQQIK-------TYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIE 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    917 SQSSQ----RTGKGQPSNK-EDVDDLV-------------SQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNk 978
Cdd:PHA02562  252 DPSAAlnklNTAAAKIKSKiEQFQKVIkmyekggvcptctQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMD- 330

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1850342    979 ekQVTEEVRKNIEVRLKESAEFQT--QLEKKLMEVEKEKQELQD---DKRRAIESMEQQLSELKKTLSSVQNEVQE 1049
Cdd:PHA02562  331 --EFNEQSKKLLELKNKISTNKQSliTLVDKAKKVKAAIEELQAefvDNAEELAKLQDELDKIVKTKSELVKEKYH 404
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
679-861 2.47e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   679 FENYKKEKAENEKIQ--NEQLEKLQEQVTDLRSQNTKISTQLDFASK--RYEMLQDNVEGYRREITSLHERNQKLTATTQ 754
Cdd:COG4913  606 FDNRAKLAALEAELAelEEELAEAEERLEALEAELDALQERREALQRlaEYSWDEIDVASAEREIAELEAELERLDASSD 685

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   755 kqeqiintmtqDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLL------------AEQRGQNLLLTNLQT- 821
Cdd:COG4913  686 -----------DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEeeldelqdrleaAEDLARLELRALLEEr 754

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 1850342   822 -IQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQ 861
Cdd:COG4913  755 fAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
PRK09039 PRK09039
peptidoglycan -binding protein;
1475-1595 2.71e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 45.73  E-value: 2.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1475 EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKT- 1553
Cdd:PRK09039   61 QIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARALAQVe 140

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1850342   1554 --RKAIVAAKSKIAHLAGVKDQLTKENEE-------LKQR-NGALDQQKDEL 1595
Cdd:PRK09039  141 llNQQIAALRRQLAALEAALDASEKRDREsqakiadLGRRlNVALAQRVQEL 192
PRK12704 PRK12704
phosphodiesterase; Provisional
 1484-1615 2.93e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.92  E-value: 2.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1484 NQAETKSKSLESQVEnlqKTLSEKETEARNL-QEQTVQLQSELSRLRQDLQDRTTQEeqlRQQITEKEEKTRKaivaaks 1562
Cdd:PRK12704   27 KIAEAKIKEAEEEAK---RILEEAKKEAEAIkKEALLEAKEEIHKLRNEFEKELRER---RNELQKLEKRLLQ------- 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1850342   1563 KIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLER 1615
Cdd:PRK12704   94 KEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELER 146
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 894-1051 3.44e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.53  E-value: 3.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   894 LKNAQKEIATLKRHLSNMEVQVASQSSQRTGKgqpsnKEDVDDLVSQLRQTEEQVNDLKERLKTST------SNVEQYQA 967
Cdd:COG1579   19 LDRLEHRLKELPAELAELEDELAALEARLEAA-----KTELEDLEKEIKRLELEIEEVEARIKKYEeqlgnvRNNKEYEA 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   968 MvTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEV 1047
Cdd:COG1579   94 L-QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKI 172


                 ....
gi 1850342  1048 QEAL 1051
Cdd:COG1579  173 PPEL 176
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1435-1632 4.07e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 4.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1435 KKIGRRYKTQYEELKAQQDKVMETSAQssgdHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLqktlsEKETEARNL 1514
Cdd:COG4717   60 KPQGRKPELNLKELKELEEELKEAEEK----EEEYAELQEELEELEEELEELEAELEELREELEKL-----EKLLQLLPL 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1515 QEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDE 1594
Cdd:COG4717  131 YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAE 210

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 1850342  1595 LDVRITALKSqyegRISRLERELREHQERHLEQRDEPQ 1632
Cdd:COG4717  211 LEEELEEAQE----ELEELEEELEQLENELEAAALEER 244
PRK01156 PRK01156
chromosome segregation protein; Provisional
 232-760 4.11e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 45.66  E-value: 4.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    232 EVSRLEEQMNGLKTSNEHLQKHV---EDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVE 308
Cdd:PRK01156  160 EINSLERNYDKLKDVIDMLRAEIsniDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKS 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    309 ELHKLLKEAGEANKAIQDhlLEVEQSKDQMEKEMLEKIGRLEKELE---------NANDLLSATKRKGAILSEEELaaMS 379
Cdd:PRK01156  240 ALNELSSLEDMKNRYESE--IKTAESDLSMELEKNNYYKELEERHMkiindpvykNRNYINDYFKYKNDIENKKQI--LS 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    380 PTAAAVAKIVKPGMKLTELYNAYvetqDQLLLEKLENKRINKYLDEI----------VKEVEAKapilKRQREEYERAQK 449
Cdd:PRK01156  316 NIDAEINKYHAIIKKLSVLQKDY----NDYIKKKSRYDDLNNQILELegyemdynsyLKSIESL----KKKIEEYSKNIE 387

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    450 avaslsvKLEQAMKEIQRLQE-DTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGN-HVIRDEEVSSADIS 527
Cdd:PRK01156  388 -------RMSAFISEILKIQEiDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNmEMLNGQSVCPVCGT 460

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    528 SSSEVISQHLVSYRN-----IEELQQQNQRLLVALRELGETREREEQETTSSKITELQL---KLESALTELEQLR----- 594
Cdd:PRK01156  461 TLGEEKSNHIINHYNekksrLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINeynKIESARADLEDIKikine 540

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    595 -----------KSRQHQMQLVDsIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVS--------TPA 655
Cdd:PRK01156  541 lkdkhdkyeeiKNRYKSLKLED-LDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIgfpddksyIDK 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    656 PVPVIES---------TEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEkLQEQVTDLRSQNTKISTQLDFASKRYE 726
Cdd:PRK01156  620 SIREIENeannlnnkyNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKE-ITSRINDIEDNLKKSRKALDDAKANRA 698

                         570       580       590
                  ....*....|....*....|....*....|....
gi 1850342    727 MLQDNVEGYRREITSLHERNQKLTATTQKQEQII 760
Cdd:PRK01156  699 RLESTIEILRTRINELSDRINDINETLESMKKIK 732
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
931-1598 4.50e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.50e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   931 KEDVDDLVS---QLRQTEEQVNDLK------ERLKTSTSNVEQYQAMVTSL-----EESLNKEKQVTEEVRKNIEVRLKE 996
Cdd:COG4913  231 VEHFDDLERaheALEDAREQIELLEpirelaERYAAARERLAELEYLRAALrlwfaQRRLELLEAELEELRAELARLEAE 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   997 SAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQN---EVQEALQRASTALSNEQQA----RRDCQ 1069
Cdd:COG4913  311 LERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERrraRLEALLAALGLPLPASAEEfaalRAEAA 390

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1070 EQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSK---------------MASVRQHLEETTQKAESQ------LLECK 1128
Cdd:COG4913  391 ALLEALEEELEALEEALAEAEAALRDLRRELRELEAeiaslerrksniparLLALRDALAEALGLDEAElpfvgeLIEVR 470

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1129 ---ASWEE---------RERMLKDEvskcvcrcEDLEKQNRLLHDqiEKLSDKVVAS-VKEGVQGPLNVSLSEEGksqeq 1195
Cdd:COG4913  471 peeERWRGaiervlggfALTLLVPP--------EHYAAALRWVNR--LHLRGRLVYErVRTGLPDPERPRLDPDS----- 535

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1196 ILEILRF----IRR--EKEIAEtRFEVAQVESL----RY---------------------RQRVELLERELQELQDSLNA 1244
Cdd:COG4913  536 LAGKLDFkphpFRAwlEAELGR-RFDYVCVDSPeelrRHpraitragqvkgngtrhekddRRRIRSRYVLGFDNRAKLAA 614

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1245 EREKVQVTAKTMAQHEELMKKTETmnvVMETNKMLREEKERLEQ------DLQQMQAKVRKLELDILPLQEANAELSEks 1318
Cdd:COG4913  615 LEAELAELEEELAEAEERLEALEA---ELDALQERREALQRLAEyswdeiDVASAEREIAELEAELERLDASSDDLAA-- 689

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1319 gmlqaekklLEEDVKRWKARNQHLvsqqkdpdTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARsnASLTNNQNLIQS 1398
Cdd:COG4913  690 ---------LEEQLEELEAELEEL--------EEELDELKGEIGRLEKELEQAEEELDELQDRLEA--AEDLARLELRAL 750

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1399 LKEDLNKVRTEK--ETIQKDLDAKIIDIQEKV-KTITQVKKIGRRYKTQYEELKAQQDkvmeTSAQSSGDHQEQHVSVQE 1475
Cdd:COG4913  751 LEERFAAALGDAveRELRENLEERIDALRARLnRAEEELERAMRAFNREWPAETADLD----ADLESLPEYLALLDRLEE 826

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1476 ------MQELKETLNQAETKSkslesqVENLQKTLsekETEARNLQEQTVQLQSEL--------SRLRQDLQDRTTQE-E 1540
Cdd:COG4913  827 dglpeyEERFKELLNENSIEF------VADLLSKL---RRAIREIKERIDPLNDSLkripfgpgRYLRLEARPRPDPEvR 897

                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 1850342  1541 QLRQQITEKEEK-TRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNgaldqQKDELDVR 1598
Cdd:COG4913  898 EFRQELRAVTSGaSLFDEELSEARFAALKRLIERLRSEEEESDRRW-----RARVLDVR 951
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1367-1588 5.08e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.15  E-value: 5.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1367 RIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLdakiidiqekvktitqvkkigRRYKTQYE 1446
Cdd:COG1579   11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEI---------------------KRLELEIE 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1447 ELKAQQDKVmetsaqssgdhQEQHVSVQEMQELketlnqaetksKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELS 1526
Cdd:COG1579   70 EVEARIKKY-----------EEQLGNVRNNKEY-----------EALQKEIESLKRRISDLEDEILELMERIEELEEELA 127

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1850342  1527 RLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLA-GVKDQLTKENEELKQRNGAL 1588
Cdd:COG1579  128 ELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAaKIPPELLALYERIRKRKNGL 190
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
970-1551 6.31e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 6.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    970 TSLEESLNKEKQVTEEVRKNIEVrlKESAEFQTQL---EKKLMEVEKEKQELQDDKRRAIESME-------------QQL 1033
Cdd:PRK02224  176 LGVERVLSDQRGSLDQLKAQIEE--KEEKDLHERLnglESELAELDEEIERYEEQREQARETRDeadevleeheerrEEL 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1034 SELKKTLSSVQNEVQEAlQRASTALSNEQQARRDCQEQAKiavEAQNKYERELMLHAADVEALQAAKEQVSKmasvrqHL 1113
Cdd:PRK02224  254 ETLEAEIEDLRETIAET-EREREELAEEVRDLRERLEELE---EERDDLLAEAGLDDADAEAVEARREELED------RD 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1114 EETTQKAESQLLECKASWEERERMLKDevskcvcrCEDLEKQNRLLHDQIEKLsDKVVASVKEGVqgplnvslseeGKSQ 1193
Cdd:PRK02224  324 EELRDRLEECRVAAQAHNEEAESLRED--------ADDLEERAEELREEAAEL-ESELEEAREAV-----------EDRR 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1194 EQILEIlrfiRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELM---KKTETMN 1270
Cdd:PRK02224  384 EEIEEL----EEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLeagKCPECGQ 459

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1271 VV-----METNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEAnAELSEKSGMLQAEKKLLEE--DVKRWKARNQHLV 1343
Cdd:PRK02224  460 PVegsphVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDL-VEAEDRIERLEERREDLEEliAERRETIEEKRER 538

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1344 SQQKDPDTEEYRkllSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLkedlNKVRTEKETIQkDLDAKIID 1423
Cdd:PRK02224  539 AEELRERAAELE---AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL----ERIRTLLAAIA-DAEDEIER 610

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1424 IQEKVKTITQVKKIGRryktqyEELKAQQDKVMETSAQSSGDhqeqhvSVQEMQELKETLnqaetkskslESQVENLQKT 1503
Cdd:PRK02224  611 LREKREALAELNDERR------ERLAEKRERKRELEAEFDEA------RIEEAREDKERA----------EEYLEQVEEK 668

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1850342   1504 LSEKETEARNLQEQTVQLQSELSRL------RQDLQDRTTQEEQLRQQITEKEE 1551
Cdd:PRK02224  669 LDELREERDDLQAEIGAVENELEELeelrerREALENRVEALEALYDEAEELES 722
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 291-511 6.74e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 6.74e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   291 SAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMeKEMLEKIGRLEKELENANDLLSATKRKGAIL 370
Cdd:COG4942   17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAELAELEKEIAEL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   371 SEEELAAMSPTAAAVAKIVKPGM--KLTELYNAYVETQDQLLLEKLenKRINKYLDEIVKEVEAKAPILKRQREEYERAQ 448
Cdd:COG4942   96 RAELEAQKEELAELLRALYRLGRqpPLALLLSPEDFLDAVRRLQYL--KYLAPARREQAEELRADLAELAALRAELEAER 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1850342   449 KAVASLSVKLEQAMKEIQRLQEDTDKA----NKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEAR 511
Cdd:COG4942  174 AELEALLAELEEERAALEALKAERQKLlarlEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1350-1645 6.76e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.11  E-value: 6.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1350 DTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEketiqkdldakiidiqEKVK 1429
Cdd:pfam17380  297 EQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQE----------------ERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1430 TITQVKKigrryktqyEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKEt 1509
Cdd:pfam17380  361 ELERIRQ---------EEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQE- 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1510 EARNLQEQTVQLQS--ELSRLRQDLQDRTTQEEQLRQQiteKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGA 1587
Cdd:pfam17380  431 EARQREVRRLEEERarEMERVRLEEQERQQQVERLRQQ---EEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA 507

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1850342    1588 LDQQKD-------ELDVRITALKSQYEGRISRLERElrehQERHLEQRDEPQEPSNKVPEQQRQI 1645
Cdd:pfam17380  508 MIEEERkrkllekEMEERQKAIYEEERRREAEEERR----KQQEMEERRRIQEQMRKATEERSRL 568
PTZ00121 PTZ00121
MAEBL; Provisional
 780-1421 7.40e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 7.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    780 RAENLKKEKEMLKLSEVRLS---QQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEH--EISHLKKK 854
Cdd:PTZ00121 1244 KAEEERNNEEIRKFEEARMAhfaRRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEakKADEAKKK 1323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    855 LENEVEQRHTLTRNLDvqllDTKRQLDTETNLHLNTKELLKNAQK--EIATLKRHLSNMEVQVASQSSQRTGKGQPSNK- 931
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAE----EAKKAAEAAKAEAEAAADEAEAAEEkaEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKk 1399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    932 -EDVDDLVSQLRQTEEQVNDLKErLKTSTSNVEQYQAMVTSLEESlnkeKQVTEEVRKNIEVRLKESAEFQTQLEKKLME 1010
Cdd:PTZ00121 1400 aEEDKKKADELKKAAAAKKKADE-AKKKAEEKKKADEAKKKAEEA----KKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1011 VEKEKQELQ--DDKRRAIESMEQQLSELKKtlSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELML 1088
Cdd:PTZ00121 1475 AKKKAEEAKkaDEAKKKAEEAKKKADEAKK--AAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1089 HAADV-------EALQAAKEQVSKMASVRQhLEETTQKAESQLLECKASWEERERMLKDEVSKC---VCRCEDLEKQNRL 1158
Cdd:PTZ00121 1553 KAEELkkaeekkKAEEAKKAEEDKNMALRK-AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAeeaKIKAEELKKAEEE 1631

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1159 lHDQIEKLSDKVVASVKEGVQ-----GPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVA--QVESLRYRQRVELL 1231
Cdd:PTZ00121 1632 -KKKVEQLKKKEAEEKKKAEElkkaeEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALkkEAEEAKKAEELKKK 1710

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1232 ERELQELQDSLNAEREKVQVTAktmaqhEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEAN 1311
Cdd:PTZ00121 1711 EAEEKKKAEELKKAEEENKIKA------EEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1312 AELSEKSGMLQAEKKLLE-----EDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEV---HTKRIQQLTEEIGRLKAEIA 1383
Cdd:PTZ00121 1785 LDEEDEKRRMEVDKKIKDifdnfANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMqleEADAFEKHKFNKNNENGEDG 1864

                         650       660       670
                  ....*....|....*....|....*....|....*...
gi 1850342   1384 RSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKI 1421
Cdd:PTZ00121 1865 NKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREI 1902
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 51-325 8.01e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.53  E-value: 8.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     51 EQQYFEIEKRlshsQERLVNE-TRECQSLRLELEKLNNQLKALTEKNKeleiaqdrniaiqsqfTRTKEELEAEKRDLIR 129
Cdd:PRK05771   27 ELGVVHIEDL----KEELSNErLRKLRSLLTKLSEALDKLRSYLPKLN----------------PLREEKKKVSVKSLEE 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    130 TNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQ-----ASDVSVKYREKRLEQ------EKELLHSQNTWLN 198
Cdd:PRK05771   87 LIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEpwgnfDLDLSLLLGFKYVSVfvgtvpEDKLEELKLESDV 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    199 TELKTKTDE------LLALGREKGNEILELKCNLENKKEEVS---RLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQqa 269
Cdd:PRK05771  167 ENVEYISTDkgyvyvVVVVLKELSDEVEEELKKLGFERLELEeegTPSELIREIKEELEEIEKERESLLEELKELAKK-- 244

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1850342    270 smEEKFHneLNAHIKLSNLYKSAaddsEAKSNELT-------------RAVEELHKLLKEAGEANKAIQ 325
Cdd:PRK05771  245 --YLEEL--LALYEYLEIELERA----EALSKFLKtdktfaiegwvpeDRVKKLKELIDKATGGSAYVE 305
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
77-366 8.56e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 43.75  E-value: 8.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    77 SLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESN 156
Cdd:COG1340    5 ELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELN 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   157 TTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSqntwLNTELKTKTdellaLGREKGNEILelkcnlenkkEEVSRL 236
Cdd:COG1340   85 EKLNELREELDELRKELAELNKAGGSIDKLRKEIER----LEWRQQTEV-----LSPEEEKELV----------EKIKEL 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   237 EEQMNGLKTSNEhLQKHVEDLLTKLKEAKEQQasmeEKFHNELnahiklsnlyKSAADDSEAKSNELTRAVEELHKLLKE 316
Cdd:COG1340  146 EKELEKAKKALE-KNEKLKELRAELKELRKEA----EEIHKKI----------KELAEEAQELHEEMIELYKEADELRKE 210

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 1850342   317 AGEANKAIQDHLLEVEQSKDQmEKEMLEKIGRLEKELENANDLLSATKRK 366
Cdd:COG1340  211 ADELHKEIVEAQEKADELHEE-IIELQKELRELRKELKKLRKKQRALKRE 259
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1396-1661 9.23e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 44.43  E-value: 9.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1396 IQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELK-----------AQQDKVMETSAQSSg 1464
Cdd:pfam10174  242 ISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKqelskkesellALQTKLETLTNQNS- 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1465 dHQEQHVSVqemqeLKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDrttqeeqLRQ 1544
Cdd:pfam10174  321 -DCKQHIEV-----LKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRD-------LKD 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1545 QITEKEektRKAIVAAKsKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALK---SQYEGRISRL----EREL 1617
Cdd:pfam10174  388 MLDVKE---RKINVLQK-KIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEealSEKERIIERLkeqrERED 463

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1850342    1618 REHQERHLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIAST 1661
Cdd:pfam10174  464 RERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASS 507
FPP pfam05911
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ...
 181-282 1.05e-03

Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.


Pssm-ID: 461778 [Multi-domain]  Cd Length: 859  Bit Score: 44.28  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     181 KRLEQEKELLHSQNTWLNTELKTKTDELLALG---REKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDL 257
Cdd:pfam05911  684 KRLKEEFEQLKSEKENLEVELASCTENLESTKsqlQESEQLIAELRSELASLKESNSLAETQLKCMAESYEDLETRLTEL 763

                           90       100
                   ....*....|....*....|....*
gi 1850342     258 LTKLKEAKEQQASMEEKFHNELNAH 282
Cdd:pfam05911  764 EAELNELRQKFEALEVELEEEKNCH 788
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
965-1380 1.08e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   965 YQAMVTSLEESLNKEKQvtEEVRKNIEVRLKESAEFQtQLEKKLMEVEKEKQELQDdKRRAIESMEQQLSELKKTLSSVQ 1044
Cdd:COG4717   40 LAFIRAMLLERLEKEAD--ELFKPQGRKPELNLKELK-ELEEELKEAEEKEEEYAE-LQEELEELEEELEELEAELEELR 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1045 NEVqEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQL 1124
Cdd:COG4717  116 EEL-EKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEEL 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1125 LECKASWEE---RERMLKDEVSKCVCRCEDLEKQ------NRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQ 1195
Cdd:COG4717  195 QDLAEELEElqqRLAELEEELEEAQEELEELEEEleqlenELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILT 274

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1196 ILEIL-----------RFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMK 1264
Cdd:COG4717  275 IAGVLflvlgllallfLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR 354

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1265 KTETMNVVMETNKMLREEKERLE-----------------QDLQQMQAKVRKLELDILPLQEAN---------AELSEKS 1318
Cdd:COG4717  355 EAEELEEELQLEELEQEIAALLAeagvedeeelraaleqaEEYQELKEELEELEEQLEELLGELeellealdeEELEEEL 434

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1850342  1319 GMLQAEKKLLEEDVKRWKARNQHLVSQQKD-PDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKA 1380
Cdd:COG4717  435 EELEEELEELEEELEELREELAELEAELEQlEEDGELAELLQELEELKAELRELAEEWAALKL 497
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 413-1206 1.15e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.27  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     413 KLENKRINKYLDEIVKEVEAKAPilKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQ 492
Cdd:TIGR00606  278 KKQMEKDNSELELKMEKVFQGTD--EQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQ 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     493 VKDLSQQIRVLLMELEEargNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRE---LGETREREEQ 569
Cdd:TIGR00606  356 ADRHQEHIRARDSLIQS---LATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSkerLKQEQADEIR 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     570 ETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSivrqrdMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQ 649
Cdd:TIGR00606  433 DEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGS------SDRILELDQELRKAERELSKAEKNSLTETLKKEVKSL 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     650 TVstpapvpviESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKlQEQVTDLRSQNTKISTQLDFASKRYEMLQ 729
Cdd:TIGR00606  507 QN---------EKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDK-DEQIRKIKSRHSDELTSLLGYFPNKKQLE 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     730 DNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMlklsEVRLSQQRESLLAEQ 809
Cdd:TIGR00606  577 DWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE----ESDLERLKEEIEKSS 652

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     810 RGQNLLLTNLQTIQGILERSETETKQ--RLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLH 887
Cdd:TIGR00606  653 KQRAMLAGATAVYSQFITQLTDENQSccPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLA 732

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     888 LNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQRTgkgqpSNKEDVDDLVSQLRQTEEQVNDLK--ERLKTSTSNVEQY 965
Cdd:TIGR00606  733 PGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIE-----EQETLLGTIMPEEESAKVCLTDVTimERFQMELKDVERK 807

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     966 QAMVTSLEESLNKEKQVTEeVRKNIEvrlkesaEFQTQLEKKLMEVEkEKQELQDDKRRAIESMEQQLSELKktlsSVQN 1045
Cdd:TIGR00606  808 IAQQAAKLQGSDLDRTVQQ-VNQEKQ-------EKQHELDTVVSKIE-LNRKLIQDQQEQIQHLKSKTNELK----SEKL 874

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1046 EVQEALQRASTAlsnEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMasvrqhlEETTQKAESQLL 1125
Cdd:TIGR00606  875 QIGTNLQRRQQF---EEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSK-------ETSNKKAQDKVN 944

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1126 ECKASWEERERMLKDEVSKCVCRCEDLEKQnrllhdqieklsdkvvasvKEGVQGPLNVSLSEEGKSQEQILEILRFIRR 1205
Cdd:TIGR00606  945 DIKEKVKNIHGYMKDIENKIQDGKDDYLKQ-------------------KETELNTVNAQLEECEKHQEKINEDMRLMRQ 1005


                   .
gi 1850342    1206 E 1206
Cdd:TIGR00606 1006 D 1006
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 1242-1406 1.17e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 44.25  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1242 LNAEREKVQVTAKTMAQHEELMKKTE-TMNVVMETNKMLREEKERLEQDLqqmqaKVRKLELDILPLQEANaeLSEKSGM 1320
Cdd:pfam05667  337 LEELQEQLEDLESSIQELEKEIKKLEsSIKQVEEELEELKEQNEELEKQY-----KVKKKTLDLLPDAEEN--IAKLQAL 409

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1321 LQAEKKLLEEDVKRWKARnqhlvsqqKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1400
Cdd:pfam05667  410 VDASAQRLVELAGQWEKH--------RVPLIEEYRALKEAKSNKEDESQRKLEEIKELREKIKEVAEEAKQKEELYKQLV 481


                   ....*.
gi 1850342    1401 EDLNKV 1406
Cdd:pfam05667  482 AEYERL 487
mukB PRK04863
chromosome partition protein MukB;
1246-1645 1.19e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.56  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1246 REKVQVTAKTMAQHEELMkkTETMNVVmeTNKMLREEKER---LEQDL---QQMQAKVRKLELDilplQEANAELSEKSG 1319
Cdd:PRK04863  246 LEAIRVTQSDRDLFKHLI--TESTNYV--AADYMRHANERrvhLEEALelrRELYTSRRQLAAE----QYRLVEMARELA 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1320 MLQAEKKLLEEDvkrWKARNQHLVSqqkdpdteeyrkllsekeVHTKRIQQltEEIGRLKAEIARSNASLTNNQNLIQSL 1399
Cdd:PRK04863  318 ELNEAESDLEQD---YQAASDHLNL------------------VQTALRQQ--EKIERYQADLEELEERLEEQNEVVEEA 374

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1400 KEDLNKVRTEKETIQKDLD---AKIIDIQEKVktITQVKKIG--RRYKTQYEELKAQQDkVMETSAQSSGDHQEQHVSvq 1474
Cdd:PRK04863  375 DEQQEENEARAEAAEEEVDelkSQLADYQQAL--DVQQTRAIqyQQAVQALERAKQLCG-LPDLTADNAEDWLEEFQA-- 449

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1475 EMQELKETLNQAETKSKSLE----------------------SQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDL 1532
Cdd:PRK04863  450 KEQEATEELLSLEQKLSVAQaahsqfeqayqlvrkiagevsrSEAWDVARELLRRLREQRHLAEQLQQLRMRLSELEQRL 529

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1533 QDRTTQeEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQ------Y 1606
Cdd:PRK04863  530 RQQQRA-ERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARapawlaA 608

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 1850342   1607 EGRISRLERELREHQE----------RHLEQRDEPQEPSNKVPEQQRQI 1645
Cdd:PRK04863  609 QDALARLREQSGEEFEdsqdvteymqQLLERERELTVERDELAARKQAL 657
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
984-1506 1.30e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   984 EEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDdKRRAIESMEQQLSELKKTLSSVQNEVQEaLQRASTALSNEQQ 1063
Cdd:COG4717   49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEE-KEEEYAELQEELEELEEELEELEAELEE-LREELEKLEKLLQ 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1064 ARRDCQEQAKIAVEAQNKYERelmLHAADvEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVS 1143
Cdd:COG4717  127 LLPLYQELEALEAELAELPER---LEELE-ERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1144 KCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLR 1223
Cdd:COG4717  203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1224 YRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKL--E 1301
Cdd:COG4717  283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELeeE 362

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1302 LDILPLQEANAELSEKSGMlqaekklleedvkrwkarnqhlvsqqkdPDTEEYRKLLSEKEvhtkRIQQLTEEIGRLKAE 1381
Cdd:COG4717  363 LQLEELEQEIAALLAEAGV----------------------------EDEEELRAALEQAE----EYQELKEELEELEEQ 410

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1382 IARSNASLTNNQNLIQ--SLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRryktqYEELKAQQdkvmets 1459
Cdd:COG4717  411 LEELLGELEELLEALDeeELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGE-----LAELLQEL------- 478

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*..
gi 1850342  1460 aqssgdhqeqhvsvqemQELKETLNQAETKSKSLESQVENLQKTLSE 1506
Cdd:COG4717  479 -----------------EELKAELRELAEEWAALKLALELLEEAREE 508
Filament pfam00038
Intermediate filament protein;
765-1087 1.39e-03

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 43.37  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     765 QDLRGANEKLAVAEIRAENLKKEKEMLklsEVRLSQQRESLLAEQRG-QNLLLTNLQTIQGILERSETEtKQRLSSQIEK 843
Cdd:pfam00038    4 EQLQELNDRLASYIDKVRFLEQQNKLL---ETKISELRQKKGAEPSRlYSLYEKEIEDLRRQLDTLTVE-RARLQLELDN 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     844 LEHEISHLKKKLENEVEQRhtltRNLDVQLLDTKRQLDTETnlhLNTKELlknaQKEIATLKrhlsnmevqvasqssqrt 923
Cdd:pfam00038   80 LRLAAEDFRQKYEDELNLR----TSAENDLVGLRKDLDEAT---LARVDL----EAKIESLK------------------ 130

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     924 gkgqpsnkedvDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEvrknIEVRLKESAE--FQ 1001
Cdd:pfam00038  131 -----------EELAFLKKNHEEEVRELQAQVSDTQVNVEMDAARKLDLTSALAEIRAQYEE----IAAKNREEAEewYQ 195

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1002 TQLEKKLMEVEKEKQELQDDK------RRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQ---A 1072
Cdd:pfam00038  196 SKLEELQQAAARNGDALRSAKeeitelRRTIQSLEIELQSLKKQKASLERQLAETEERYELQLADYQELISELEAElqeT 275

                          330
                   ....*....|....*
gi 1850342    1073 KIAVEAQNKYERELM 1087
Cdd:pfam00038  276 RQEMARQLREYQELL 290
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1274-1496 1.59e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1274 ETNKMLREEKERLEQDLQQMQAKVR--KLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDT 1351
Cdd:COG3206  175 KALEFLEEQLPELRKELEEAEAALEefRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPD 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1352 EEYRKLLSEkevhtkRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEketIQKDLDAKIIDIQEKVKTI 1431
Cdd:COG3206  255 ALPELLQSP------VIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ---LQQEAQRILASLEAELEAL 325

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1850342  1432 tqvkkigrryKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQ 1496
Cdd:COG3206  326 ----------QAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLA 380
PRK12705 PRK12705
hypothetical protein; Provisional
 1498-1619 1.64e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 43.54  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1498 ENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKskIAHLAGVKDQLTKE 1577
Cdd:PRK12705   33 KEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDAR--AEKLDNLENQLEER 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1850342   1578 NEELKQRNGALDQQKDELD---VRITALkSQYEGR---ISRLERELRE 1619
Cdd:PRK12705  111 EKALSARELELEELEKQLDnelYRVAGL-TPEQARkllLKLLDAELEE 157
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
930-1098 1.65e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   930 NKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRlkesaefqtQLEKKLM 1009
Cdd:COG3206  203 QKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQ---------QLRAQLA 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1010 EVEKEKQELQ---DDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYEREL 1086
Cdd:COG3206  274 ELEAELAELSaryTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAEL 353

                        170
                 ....*....|..
gi 1850342  1087 MLHAADVEALQA 1098
Cdd:COG3206  354 RRLEREVEVARE 365
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
132-316 1.87e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   132 ERLSQELEYLTEDVKRLNEKLKESNTTKGELQ------LKLDELQASDVSVKYREKRLEQ-EKELlhsqntwlnTELKTK 204
Cdd:COG4913  613 AALEAELAELEEELAEAEERLEALEAELDALQerrealQRLAEYSWDEIDVASAEREIAElEAEL---------ERLDAS 683

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   205 TDELLALGREkgneilelkcnLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKF----HNELN 280
Cdd:COG4913  684 SDDLAALEEQ-----------LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLArlelRALLE 752

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 1850342   281 AHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKE 316
Cdd:COG4913  753 ERFAAALGDAVERELRENLEERIDALRARLNRAEEE 788
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 1640-1877 2.13e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 43.02  E-value: 2.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1640 EQQRQITLKTTPASGErgiaSTSDPPTANIKPTPVVSTPSKV---TAAAMAG----NKSTPRASIRPMVTPATVTNPTTT 1712
Cdd:pfam17823   89 EHTPHGTDLSEPATRE----GAADGAASRALAAAASSSPSSAaqsLPAAIAAlpseAFSAPRAAACRANASAAPRAAIAA 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1713 PTA----TVMPTTQVESQEAMQSEGPVEHVPVFGSTS---------GSVRSTSPNVQPSISQ-----PILTVQQQTQATA 1774
Cdd:pfam17823  165 ASAphaaSPAPRTAASSTTAASSTTAASSAPTTAASSapatltparGISTAATATGHPAAGTalaavGNSSPAAGTVTAA 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1775 FVQPTQQSHPQIEPANQELSSNIVEVVQSSPVER---PSTSTAVfGTVSATPSSSLpkrtREEEEDSTIEAS-DQVSDDT 1850
Cdd:pfam17823  245 VGTVTPAALATLAAAAGTVASAAGTINMGDPHARrlsPAKHMPS-DTMARNPAAPM----GAQAQGPIIQVStDQPVHNT 319

                          250       260
                   ....*....|....*....|....*..
gi 1850342    1851 VEMPLPKKLKSVTPVGTEEEVMAEEST 1877
Cdd:pfam17823  320 AGEPTPSPSNTTLEPNTPKSVASTNLA 346
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 1284-1640 2.16e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 43.50  E-value: 2.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1284 ERLEQDLQQMQAKVRKLELDIlplqeanaelSEKSGMLQAEKKLLEEDVKR--------------WKARNQHLVSQQKDP 1349
Cdd:PTZ00108 1002 GKLERELARLSNKVRFIKHVI----------NGELVITNAKKKDLVKELKKlgyvrfkdiikkksEKITAEEEEGAEEDD 1071

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1350 D------------TEEYRKLLSekevhtKRIQQLTEE-IGRLKAEIARSNASLTN--NQNLIQSLKEDLNKVRTEKETIQ 1414
Cdd:PTZ00108 1072 EaddeddeeelgaAVSYDYLLS------MPIWSLTKEkVEKLNAELEKKEKELEKlkNTTPKDMWLEDLDKFEEALEEQE 1145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1415 KDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLE 1494
Cdd:PTZ00108 1146 EVEEKEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQ 1225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1495 SQVENLQKTLSEKETEARNLQEQTVQLQSELS---RLRQDLQDRTTQEEQLR-------QQITEKEEKTRKAIVAAKSKI 1564
Cdd:PTZ00108 1226 EDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNdefSSDDLSKEGKPKNAPKRvsavqysPPPPSKRPDGESNGGSKPSSP 1305

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1850342   1565 AHlAGVKDQLTKENEELKQRNGAldQQKDELDVRITALKSQYEGR-ISRLERELREHQERHLEQRDEPQEPSNKVPE 1640
Cdd:PTZ00108 1306 TK-KKVKKRLEGSLAALKKKKKS--EKKTARKKKSKTRVKQASASqSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDE 1379
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 51-548 2.37e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 2.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      51 EQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQD--RNIAIQSQFTRTKEELEAEKRDLI 128
Cdd:TIGR00618  238 TQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKaaPLAAHIKAVTQIEQQAQRIHTELQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     129 RTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKrLEQEKELLHSQNTW------LNTELK 202
Cdd:TIGR00618  318 SKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREI-SCQQHTLTQHIHTLqqqkttLTQKLQ 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     203 TKTDELLALGREKGnEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAH 282
Cdd:TIGR00618  397 SLCKELDILQREQA-TIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQL 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     283 IKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQD-HLLEVEQSKDQmekEMLEKIGRLEKELENANDLLS 361
Cdd:TIGR00618  476 QTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDiDNPGPLTRRMQ---RGEQTYAQLETSEEDVYHQLT 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     362 ATKRKGAILSEEELAAMSPTaaavakivkpgMKLTELYNAYVETQDQLLleklenKRINKYLDEIVKEVEAKAPILKRQR 441
Cdd:TIGR00618  553 SERKQRASLKEQMQEIQQSF-----------SILTQCDNRSKEDIPNLQ------NITVRLQDLTEKLSEAEDMLACEQH 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     442 EEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNR---RMEIQVKDLSQQIRVLLMELEEARGNHVIRD 518
Cdd:TIGR00618  616 ALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVRehaLSIRVLPKELLASRQLALQKMQSEKEQLTYW 695

                          490       500       510
                   ....*....|....*....|....*....|
gi 1850342     519 EEVSSADISSSSEVISQHLVSYRNIEELQQ 548
Cdd:TIGR00618  696 KEMLAQCQTLLRELETHIEEYDREFNEIEN 725
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1649-1825 2.49e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 43.37  E-value: 2.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1649 TTPASGERGIASTSDPPTAN-IKPTPVVSTPSKVTAAAMAGNKSTPRASIRPmvtpaTVTNPTTTPTATVMPTTQVESQE 1727
Cdd:pfam05109  535 TSPTLGKTSPTSAVTTPTPNaTSPTPAVTTPTPNATIPTLGKTSPTSAVTTP-----TPNATSPTVGETSPQANTTNHTL 609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1728 AMQSEGPVEHVPVFGSTSG---------SVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHP-------QIEPAnq 1791
Cdd:pfam05109  610 GGTSSTPVVTSPPKNATSAvttgqhnitSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPtggenitQVTPA-- 687

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1850342    1792 elSSNIVEVVQSSPVERPSTSTAVFGTVSATPSS 1825
Cdd:pfam05109  688 --STSTHHVSTSSPAPRPGTTSQASGPGNSSTST 719
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
29-267 2.83e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 2.83e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    29 LADQQSEIDGLKGRH---EKFKVESEQQYFEIEKRLSHSQeRLVNETREC---QSLRLELEKLNNQLKALTEKNKELEIA 102
Cdd:COG4913  612 LAALEAELAELEEELaeaEERLEALEAELDALQERREALQ-RLAEYSWDEidvASAEREIAELEAELERLDASSDDLAAL 690

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   103 QDRNIAIQSQFtrtkEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKE-SNTTKGELQLKLDELQASDVsvkyREK 181
Cdd:COG4913  691 EEQLEELEAEL----EELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaEDLARLELRALLEERFAAAL----GDA 762

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   182 RLEQEKELLHSQNTWLNTELKTKTDEL-----------------LALGREKGNEILELKCNLENkkEEVSRLEEQMNGLK 244
Cdd:COG4913  763 VERELRENLEERIDALRARLNRAEEELeramrafnrewpaetadLDADLESLPEYLALLDRLEE--DGLPEYEERFKELL 840

                        250       260
                 ....*....|....*....|...
gi 1850342   245 TSNEHlqKHVEDLLTKLKEAKEQ 267
Cdd:COG4913  841 NENSI--EFVADLLSKLRRAIRE 861
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 670-1216 2.86e-03

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 43.28  E-value: 2.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    670 AALKQLQEIFENYKKE--KAENEKIQNEQLEKLQEQVTDLRSQNTKIST--QLDFASKRYEMLQDNVEgyrreitSLHER 745
Cdd:PTZ00440  833 EELKQLLQKFPTEDENlnLKELEKEFNENNQIVDNIIKDIENMNKNINIikTLNIAINRSNSNKQLVE-------HLLNN 905

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    746 NQKLTATTQKQEQIINTmtQDLRGANEKLavaeIRAENLKKEKEML--KLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQ 823
Cdd:PTZ00440  906 KIDLKNKLEQHMKIINT--DNIIQKNEKL----NLLNNLNKEKEKIekQLSDTKINNLKMQIEKTLEYYDKSKENINGND 979

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    824 GI-LERSETETK--QRLSSQIEKLEHEISHLKKKLENEVEQRHTltrnlDVQLLDTKRQLDTETNLHLNTKELLKNAQKE 900
Cdd:PTZ00440  980 GThLEKLDKEKDewEHFKSEIDKLNVNYNILNKKIDDLIKKQHD-----DIIELIDKLIKEKGKEIEEKVDQYISLLEKM 1054

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    901 IATLKRHLSNMEVQvASQSSQRTGKGQpSNKEDVDDLVSQLRQTEEQVNDLKERlktSTSNVEQYQAMVTSLEESLNKEK 980
Cdd:PTZ00440 1055 KTKLSSFHFNIDIK-KYKNPKIKEEIK-LLEEKVEALLKKIDENKNKLIEIKNK---SHEHVVNADKEKNKQTEHYNKKK 1129

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    981 QVTEEVRKNIEVRLKESAEFQTQlEKKLMEVEKEKQELqddKRRAIESMEQQLSELKKTLSSVQNEVQ---EALQRASTA 1057
Cdd:PTZ00440 1130 KSLEKIYKQMEKTLKELENMNLE-DITLNEVNEIEIEY---ERILIDHIVEQINNEAKKSKTIMEEIEsykKDIDQVKKN 1205

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1058 LSNEQQARRDCQEQAKIAVEAQNKYER--ELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKA-------ESQLLECK 1128
Cdd:PTZ00440 1206 MSKERNDHLTTFEYNAYYDKATASYENieELTTEAKGLKGEANRSTNVDELKEIKLQVFSYLQQVikennkmENALHEIK 1285

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1129 ASWE-----ERERMLKdEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFI 1203
Cdd:PTZ00440 1286 NMYEflisiDSEKILK-EILNSTKKAEEFSNDAKKELEKTDNLIKQVEAKIEQAKEHKNKIYGSLEDKQIDDEIKKIEQI 1364

                         570
                  ....*....|...
gi 1850342   1204 RreKEIAETRFEV 1216
Cdd:PTZ00440 1365 K--EEISNKRKEI 1375
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 11-154 3.13e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 3.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    11 RTELNKLPKSVQnKLEKFLADQQSEIDGLKGRHEKFKVE---SEQQYFEIEKRLSHSQERL--VNETRECQSLRLELEKL 85
Cdd:COG1579   23 EHRLKELPAELA-ELEDELAALEARLEAAKTELEDLEKEikrLELEIEEVEARIKKYEEQLgnVRNNKEYEALQKEIESL 101

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1850342    86 NNQL----KALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKE 154
Cdd:COG1579  102 KRRIsdleDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
PRK05431 PRK05431
seryl-tRNA synthetase; Provisional
 1402-1504 3.87e-03

seryl-tRNA synthetase; Provisional


Pssm-ID: 235461 [Multi-domain]  Cd Length: 425  Bit Score: 42.36  E-value: 3.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1402 DLNKVRTEKETIQKDLDAK--IIDIQEKVKTITQVKKIgrryKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQEL 1479
Cdd:PRK05431    3 DIKLIRENPEAVKEALAKRgfPLDVDELLELDEERREL----QTELEELQAERNALSKEIGQAKRKGEDAEALIAEVKEL 78

                          90       100
                  ....*....|....*....|....*
gi 1850342   1480 KETLNQAETKSKSLESQVENLQKTL 1504
Cdd:PRK05431   79 KEEIKALEAELDELEAELEELLLRI 103
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1342-1652 4.10e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.65  E-value: 4.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1342 LVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQnliQSLKEDLNKVRTEKETIQKDLDAKI 1421
Cdd:pfam02463  163 AGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQ---LKEKLELEEEYLLYLDYLKLNEERI 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1422 IDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQ-EMQELKETLNQAETKSKSLESQVENL 1500
Cdd:pfam02463  240 DLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAkEEEELKSELLKLERRKVDDEEKLKES 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1501 QKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENE- 1579
Cdd:pfam02463  320 EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELEl 399

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1850342    1580 --ELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQITLKTTPA 1652
Cdd:pfam02463  400 ksEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 1639-1825 4.14e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 42.25  E-value: 4.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1639 PEQQRQITLKTTPA-SGERGIASTSDPPTANikPTPVVSTPSKVTAAAmagNKSTPRASIRPMvtPATVTNPTTTPTATV 1717
Cdd:pfam17823  275 PHARRLSPAKHMPSdTMARNPAAPMGAQAQG--PIIQVSTDQPVHNTA---GEPTPSPSNTTL--EPNTPKSVASTNLAV 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1718 MPTTQVESQEAMQSEGPVEHVpvfgSTSGSVRSTSPNVQPSisqPILTVqQQTQATAFVQPTQQSHPQIEPANQelssni 1797
Cdd:pfam17823  348 VTTTKAQAKEPSASPVPVLHT----SMIPEVEATSPTTQPS---PLLPT-QGAAGPGILLAPEQVATEATAGTA------ 413

                          170       180
                   ....*....|....*....|....*...
gi 1850342    1798 vevvQSSPVERPSTSTAVFGTVSATPSS 1825
Cdd:pfam17823  414 ----SAGPTPRSSGDPKTLAMASCQLST 437
PRK01156 PRK01156
chromosome segregation protein; Provisional
 672-1044 4.77e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.20  E-value: 4.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    672 LKQLQEIFENYKKEK-------AENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHE 744
Cdd:PRK01156  372 IESLKKKIEEYSKNIermsafiSEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNG 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    745 RNQ----KLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQResllaeqrgqnllltnlq 820
Cdd:PRK01156  452 QSVcpvcGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEE------------------ 513

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    821 tiqgiLERSETETKQ--RLSSQIEKLEHEISHLKKKlENEVEQRHTLTRNLDVQLLDTKRQ-----LDTETNLHLNTKEL 893
Cdd:PRK01156  514 -----INKSINEYNKieSARADLEDIKIKINELKDK-HDKYEEIKNRYKSLKLEDLDSKRTswlnaLAVISLIDIETNRS 587

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    894 LKN-AQKEIATLKRHLSNMEVQVASQSSQrtgkgQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSL 972
Cdd:PRK01156  588 RSNeIKKQLNDLESRLQEIEIGFPDDKSY-----IDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEI 662

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1850342    973 EESLNKEKQVTEEVrKNIEVRLKESaefQTQLEKKLMEvEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQ 1044
Cdd:PRK01156  663 DSIIPDLKEITSRI-NDIEDNLKKS---RKALDDAKAN-RARLESTIEILRTRINELSDRINDINETLESMK 729
PRK12704 PRK12704
phosphodiesterase; Provisional
 1435-1607 4.86e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 4.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1435 KKIGrryKTQYEELKAQQDKVMEtSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKEteaRNL 1514
Cdd:PRK12704   26 KKIA---EAKIKEAEEEAKRILE-EAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKE---ENL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1515 QEQtvqlQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGvkdqLTKenEELKQRngALDQQKDE 1594
Cdd:PRK12704   99 DRK----LELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISG----LTA--EEAKEI--LLEKVEEE 166

                         170
                  ....*....|...
gi 1850342   1595 LDVRITALKSQYE 1607
Cdd:PRK12704  167 ARHEAAVLIKEIE 179
PRK11637 PRK11637
AmiB activator; Provisional
 889-1108 4.94e-03

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 41.99  E-value: 4.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    889 NTKELLKNAQKEIATlkrhlsnMEVQVASQSSQRTG-KGQPSNKEDVDDLVS-QLRQTEEQVNDLKERLKTSTSNVEQYQ 966
Cdd:PRK11637   44 DNRDQLKSIQQDIAA-------KEKSVRQQQQQRASlLAQLKKQEEAISQASrKLRETQNTLNQLNKQIDELNASIAKLE 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    967 AMVTSLEESLNK---------------------EKQVTE----------EVRKNIEVRLKESAEFQTQLEKKLMEVEKEK 1015
Cdd:PRK11637  117 QQQAAQERLLAAqldaafrqgehtglqlilsgeESQRGErilayfgylnQARQETIAELKQTREELAAQKAELEEKQSQQ 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1016 QELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARrdcQEQAKIAVEAQNKYERElmlhAADVEA 1095
Cdd:PRK11637  197 KTLLYEQQAQQQKLEQARNERKKTLTGLESSLQKDQQQLSELRANESRLR---DSIARAEREAKARAERE----AREAAR 269

                         250
                  ....*....|...
gi 1850342   1096 LQAAKEQVSKMAS 1108
Cdd:PRK11637  270 VRDKQKQAKRKGS 282
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 5-272 5.15e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.41  E-value: 5.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342       5 LQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRlshsqerlVNETR-ECQSLRLELE 83
Cdd:pfam15921  543 LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKE--------INDRRlELQEFKILKD 614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      84 KLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNE----KLKESNTTK 159
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRnfrnKSEEMETTT 694

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     160 GELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALgrEKGNEILELKCNLENK-----KEEVS 234
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDAL--QSKIQFLEEAMTNANKekhflKEEKN 772

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1850342     235 RLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASME 272
Cdd:pfam15921  773 KLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
COG5022 COG5022
Myosin heavy chain [General function prediction only];
413-1069 5.23e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 42.37  E-value: 5.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   413 KLENKRINKYLDEivKEVEAKAPILKRQREEYERAQKAVASL---------SVKLEQAMKEIQRLQEDTDKANKQSSVLE 483
Cdd:COG5022  825 TIKREKKLRETEE--VEFSLKAEVLIQKFGRSLKAKKRFSLLkketiylqsAQRVELAERQLQELKIDVKSISSLKLVNL 902

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   484 RDnrrmEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHlvSYRNIEELQQQNqrllvalrelget 563
Cdd:COG5022  903 EL----ESEIIELKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYV--KLPELNKLHEVE------------- 963

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   564 rereeqettsSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSqttgvAIPLHASSLDDVSLASTPK 643
Cdd:COG5022  964 ----------SKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYG-----ALQESTKQLKELPVEVAEL 1028

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   644 RPSTSQTVSTPApvpviesTEAIEAKAA-LKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTqldFAS 722
Cdd:COG5022 1029 QSASKIISSEST-------ELSILKPLQkLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKT---INV 1098

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   723 KRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEqIINTMTQDLRGANEKLAVAEIRAENLKKEKEMlklsEVRLSQQR 802
Cdd:COG5022 1099 KDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISK-FLSQLVNTLEPVFQKLSVLQLELDGLFWEANL----EALPSPPP 1173

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   803 ESLLAEQRgqnLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKL-ENEVEQRH------TLTRNLDVQLLD 875
Cdd:COG5022 1174 FAALSEKR---LYQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLkKLISEGWVpteystSLKGFNNLNKKF 1250

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   876 TKRQLDTETNLHLNTKEL-----LKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVND 950
Cdd:COG5022 1251 DTPASMSNEKLLSLLNSIdnllsSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKSATEVNYNSEELDDWCREF 1330

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   951 LKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVR--KNIEVR-LKES---AEFQTQLEKKLME-----VEKEKQELQ 1019
Cdd:COG5022 1331 EISDVDEELEELIQAVKVLQLLKDDLNKLDELLDACYslNPAEIQnLKSRydpADKENNLPKEILKkiealLIKQELQLS 1410

                        650       660       670       680       690
                 ....*....|....*....|....*....|....*....|....*....|...
gi 1850342  1020 DDKRRAIESMEQQLSELKKTLSSVQNEV---QEALQRASTALSNEQQARRDCQ 1069
Cdd:COG5022 1411 LEGKDETEVHLSEIFSEEKSLISLDRNSiykEEVLSSLSALLTKEKIALLDRK 1463
DivIVA COG3599
Cell division septum initiation protein DivIVA, interacts with FtsZ and MinD [Cell cycle ...
 930-1038 5.40e-03

Cell division septum initiation protein DivIVA, interacts with FtsZ and MinD [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442818 [Multi-domain]  Cd Length: 125  Bit Score: 39.07  E-value: 5.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   930 NKEDVDDLVSQLRQTEEQVN----DLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVrknievrlKESAEfqTQLE 1005
Cdd:COG3599   21 DEDEVDEFLDEVAEDYERLIrenkELKEKLEELEEELEEYRELEETLQKTLVVAQETAEEV--------KENAE--KEAE 90

                         90       100       110
                 ....*....|....*....|....*....|...
gi 1850342  1006 KKLMEVEKEKQELQDDKRRAIESMEQQLSELKK 1038
Cdd:COG3599   91 LIIKEAELEAEKIIEEAQEKARKIVREIEELKR 123
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 415-602 5.66e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 5.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   415 ENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERD----NRRME 490
Cdd:COG4942   21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEiaelRAELE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   491 IQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSsevISQHLVSYRN--IEELQQQNQRLLVALRELgetreree 568
Cdd:COG4942  101 AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQ---YLKYLAPARReqAEELRADLAELAALRAEL-------- 169

                        170       180       190
                 ....*....|....*....|....*....|....
gi 1850342   569 qETTSSKITELQLKLESALTELEQLRKSRQHQMQ 602
Cdd:COG4942  170 -EAERAELEALLAELEEERAALEALKAERQKLLA 202
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
698-1168 5.73e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 5.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    698 EKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVA 777
Cdd:PRK02224  310 EAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEEL 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    778 EIRAENLKKEKEMLKLSEVRLSQQRESLLaeqrgqnllltnlqtiqgilersetETKQRLSSQIEKLEHEIshlkKKLEN 857
Cdd:PRK02224  390 EEEIEELRERFGDAPVDLGNAEDFLEELR-------------------------EERDELREREAELEATL----RTARE 440

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    858 EVEQRHTLtrnLDVQLLDTKRQlDTETNLHLNTkelLKNAQKEIATLKRHLSNMEVQVASqssqrtgkgqpsnKEDVDDL 937
Cdd:PRK02224  441 RVEEAEAL---LEAGKCPECGQ-PVEGSPHVET---IEEDRERVEELEAELEDLEEEVEE-------------VEERLER 500

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    938 VSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVtsleeslnkekqvtEEVRKNIEVRLKESAEFQTQLEKKlMEVEKEKQE 1017
Cdd:PRK02224  501 AEDLVEAEDRIERLEERREDLEELIAERRETI--------------EEKRERAEELRERAAELEAEAEEK-REAAAEAEE 565

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1018 LQDDKRRAIESMEQQLSELKKTLSSVQN--EVQEALQRASTALSN-----EQQARRDCQEQAKIAVEAQNKYERELMLHA 1090
Cdd:PRK02224  566 EAEEAREEVAELNSKLAELKERIESLERirTLLAAIADAEDEIERlrekrEALAELNDERRERLAEKRERKRELEAEFDE 645

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   1091 ADVEALQAAKEQVSK-MASVRQHLEETTQKAESQLLECKASWEERERM--LKDEVSKCVCRCEDLEKqnrlLHDQIEKLS 1167
Cdd:PRK02224  646 ARIEEAREDKERAEEyLEQVEEKLDELREERDDLQAEIGAVENELEELeeLRERREALENRVEALEA----LYDEAEELE 721


                  .
gi 1850342   1168 D 1168
Cdd:PRK02224  722 S 722
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 962-1110 5.74e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.12  E-value: 5.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    962 VEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKEsaefqtqLEKKLMEVEKEKQELQDDKrraiesmEQQLSELKKTLS 1041
Cdd:PRK00409  504 IEEAKKLIGEDKEKLNELIASLEELERELEQKAEE-------AEALLKEAEKLKEELEEKK-------EKLQEEEDKLLE 569

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1850342   1042 SVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVR 1110
Cdd:PRK00409  570 EAEKEAQQAIKEAKKEADEIIKELRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELK 638
46 PHA02562
endonuclease subunit; Provisional
 7-170 5.85e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 5.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342      7 QVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESE-----QQYFEIEKRLSHSQERLVNetrecqslrle 81
Cdd:PHA02562  242 ELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVcptctQQISEGPDRITKIKDKLKE----------- 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342     82 lekLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTN----------ERLSQELEYLTEDVKRLNEK 151
Cdd:PHA02562  311 ---LQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVdkakkvkaaiEELQAEFVDNAEELAKLQDE 387

                         170
                  ....*....|....*....
gi 1850342    152 LKESNTTKGELQLKLDELQ 170
Cdd:PHA02562  388 LDKIVKTKSELVKEKYHRG 406
mukB PRK04863
chromosome partition protein MukB;
667-1036 5.94e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.25  E-value: 5.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    667 EAKAALKQLQEIFENYKKEKAENEkiqnEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRR-----EITS 741
Cdd:PRK04863  359 ELEERLEEQNEVVEEADEQQEENE----ARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERakqlcGLPD 434

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    742 LHERN-QKLTATTQKQEQiinTMTQDLRGANEKLAVAEIRAENLKKEKEMLK-----LSEVRLSQQRESLLAEQRGQNLL 815
Cdd:PRK04863  435 LTADNaEDWLEEFQAKEQ---EATEELLSLEQKLSVAQAAHSQFEQAYQLVRkiageVSRSEAWDVARELLRRLREQRHL 511

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    816 LTNLQTIQGILersetetkqrlssqiekleheishlkkkleNEVEQRHTLTRNLDVQLLDTKRQLdtetNLHLNTKELLK 895
Cdd:PRK04863  512 AEQLQQLRMRL------------------------------SELEQRLRQQQRAERLLAEFCKRL----GKNLDDEDELE 557

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    896 NAQKEIATLKRHLSnmevqvasqssqrtgkgqpSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEEs 975
Cdd:PRK04863  558 QLQEELEARLESLS-------------------ESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLRE- 617

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1850342    976 lnkekQVTEEVrknievrlkESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSEL 1036
Cdd:PRK04863  618 -----QSGEEF---------EDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIERL 664
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1371-1616 6.60e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 41.05  E-value: 6.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1371 LTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKA 1450
Cdd:COG1340    6 LSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1451 QQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAE-----------------TKSKSLESQVENLQKTLsEKETEARN 1513
Cdd:COG1340   86 KLNELREELDELRKELAELNKAGGSIDKLRKEIERLEwrqqtevlspeeekelvEKIKELEKELEKAKKAL-EKNEKLKE 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1514 LQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITE---KEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQ 1590
Cdd:COG1340  165 LRAELKELRKEAEEIHKKIKELAEEAQELHEEMIElykEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRK 244

                        250       260
                 ....*....|....*....|....*.
gi 1850342  1591 QKDELDVRITALKSQYEGRISRLERE 1616
Cdd:COG1340  245 ELKKLRKKQRALKREKEKEELEEKAE 270
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1199-1513 6.90e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.99  E-value: 6.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1199 ILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSlNAEREKVQVTAKTMAQhEELMKKTETMNVVMETNKM 1278
Cdd:COG5022  848 IQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQLQELKID-VKSISSLKLVNLELES-EIIELKKSLSSDLIENLEF 925

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1279 LREEKERLEQDLQQMQAKVRKL----ELDIL-PLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPdtEE 1353
Cdd:COG5022  926 KTELIARLKKLLNNIDLEEGPSieyvKLPELnKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKEL--AE 1003

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1354 YRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLiQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQ 1433
Cdd:COG5022 1004 LSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSIL-KPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQ 1082

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1434 VKKIGRrykTQYEELKAQQDKVMETSAQSSGD------HQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEK 1507
Cdd:COG5022 1083 LYQLES---TENLLKTINVKDLEVTNRNLVKPanvlqfIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGL 1159


                 ....*.
gi 1850342  1508 ETEARN 1513
Cdd:COG5022 1160 FWEANL 1165
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 852-1064 7.16e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 7.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   852 KKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQ---------SSQR 922
Cdd:COG3883   18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERreelgerarALYR 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   923 TGKGQPS-----NKEDVDDLVSQ---LRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRL 994
Cdd:COG3883   98 SGGSVSYldvllGSESFSDFLDRlsaLSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   995 KESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQA 1064
Cdd:COG3883  178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAA 247
WEMBL pfam05701
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required ...
 1205-1628 8.28e-03

Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required for the chloroplast avoidance response under high intensity blue light. This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells. Acts in association with PMI2 to maintain the velocity of chloroplast photo-relocation movement via the regulation of cp-actin filaments. Thus several member-sequences are described as "myosin heavy chain-like".


Pssm-ID: 461718 [Multi-domain]  Cd Length: 562  Bit Score: 41.17  E-value: 8.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1205 REKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAERekvqvtaktmAQHEELMKKteTMNVVMetnkMLREEKE 1284
Cdd:pfam05701  159 SERDIAIKRAEEAVSASKEIEKTVEELTIELIATKESLESAH----------AAHLEAEEH--RIGAAL----AREQDKL 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1285 RLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQ---------AEKKLLEEDVKRWKARNQHLVSQQK-DPDTEEY 1354
Cdd:pfam05701  223 NWEKELKQAEEELQRLNQQLLSAKDLKSKLETASALLLdlkaelaayMESKLKEEADGEGNEKKTSTSIQAAlASAKKEL 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1355 RKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNL-------IQSLKEDLNKVRTEKETIQkdldAKIIDIQEK 1427
Cdd:pfam05701  303 EEVKANIEKAKDEVNCLRVAAASLRSELEKEKAELASLRQRegmasiaVSSLEAELNRTKSEIALVQ----AKEKEAREK 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1428 VKTITQvkkigrryKTQYEELKAQQDKVMETSAQssgdhqeqhvsvQEMQELKETLNQAETKSKSLESQVENLQK-TLSE 1506
Cdd:pfam05701  379 MVELPK--------QLQQAAQEAEEAKSLAQAAR------------EELRKAKEEAEQAKAAASTVESRLEAVLKeIEAA 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342    1507 KETEARNLQEQTVQLQSELSRLRQDLQDR------TTQE-EQLRQQITEKEEKTRKAIVAAKSKIAHlagVKDQLTKENE 1579
Cdd:pfam05701  439 KASEKLALAAIKALQESESSAESTNQEDSprgvtlSLEEyYELSKRAHEAEELANKRVAEAVSQIEE---AKESELRSLE 515

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 1850342    1580 ELKQRNGALDQQKDELDVRITALKSQYEGRISrLERELREHQERHlEQR 1628
Cdd:pfam05701  516 KLEEVNREMEERKEALKIALEKAEKAKEGKLA-AEQELRKWRAEH-EQR 562
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
250-467 9.29e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 9.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   250 LQKHVEDLLTKLKEAKEQQASMEEKfhneLNAHIKLSNlYKSAADDSEAKSNELTRAVEELHKLLKEAGEAnKAIQDHLL 329
Cdd:COG4913  622 LEEELAEAEERLEALEAELDALQER----REALQRLAE-YSWDEIDVASAEREIAELEAELERLDASSDDL-AALEEQLE 695

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   330 EVEQSKDQMEKE---MLEKIGRLEKELENANDLLSAtkrkgailseeelaamsptaaavakivkpgmkLTELYNAYVETQ 406
Cdd:COG4913  696 ELEAELEELEEEldeLKGEIGRLEKELEQAEEELDE--------------------------------LQDRLEAAEDLA 743

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1850342   407 DQLLLEKLENKRINKYLDEIVKEVEakapilKRQREEYERAQKAVASLSVKLEQAMKEIQR 467
Cdd:COG4913  744 RLELRALLEERFAAALGDAVERELR------ENLEERIDALRARLNRAEEELERAMRAFNR 798
KpsE COG3524
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
940-1073 9.37e-03

Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442746 [Multi-domain]  Cd Length: 370  Bit Score: 40.99  E-value: 9.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342   940 QLRQTEEQVNDLKERLKTSTSNVEQYQamvtsleeslNKEKQVTEEvrKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQ 1019
Cdd:COG3524  178 AVRFAEEEVERAEERLRDAREALLAFR----------NRNGILDPE--ATAEALLQLIATLEGQLAELEAELAALRSYLS 245

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1850342  1020 DDK------RRAIESMEQQLSELKKTLSSV----------------QNEVQEALQRASTALSNEQQARRDCQEQAK 1073
Cdd:COG3524  246 PNSpqvrqlRRRIAALEKQIAAERARLTGAsggdslasllaeyerlELEREFAEKAYTSALAALEQARIEAARQQR 321
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1367-1652 9.54e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 9.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1367 RIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYE 1446
Cdd:COG4372   39 ELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELE 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1447 ELKAQQDKVMETSAQSSgdhqeqhvsvQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQtvQLQSELS 1526
Cdd:COG4372  119 ELQKERQDLEQQRKQLE----------AQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEA--EAEQALD 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1850342  1527 RLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQY 1606
Cdd:COG4372  187 ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELA 266

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 1850342  1607 EGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQITLKTTPA 1652
Cdd:COG4372  267 ILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGA 312
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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