|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15404 |
PRK15404 |
high-affinity branched-chain amino acid ABC transporter substrate-binding protein; |
4-373 |
0e+00 |
|
high-affinity branched-chain amino acid ABC transporter substrate-binding protein;
Pssm-ID: 237959 [Multi-domain] Cd Length: 369 Bit Score: 670.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 4 AKKQITKLFAAMVLAGVASHSFAaDTIKIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPK 83
Cdd:PRK15404 1 MKSKGKTLLAGCIALALSHAALA-DDIKIAIVGPMSGPVAQYGDMEFTGARQAIEDINAKGGIKGDKLEGVEYDDACDPK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 84 QAVAVANKIVNDGVKFVVGHLCSSSTQPASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADHV 163
Cdd:PRK15404 80 QAVAVANKVVNDGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLIFRTIGLDSDQGPTAAKYILEKV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 164 KPKTVAVLHDKQQYGEGIATAVKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEK 243
Cdd:PRK15404 160 KPKRIAVLHDKQQYGEGLARSVKDGLKKAGANVVFFEGITAGDKDFSALIAKLKKENVDFVYYGGYHPEMGQILRQAREA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 244 GLNAKFMGPEGVGNDSISQIAQGASEGLLVTLPQAFDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKS 323
Cdd:PRK15404 240 GLKTQFMGPEGVGNKSLSNIAGPASEGMLVTLPKRYDQDPANKAIVDAFKAKKQDPSGPFVWTTYAAVQSLAAGINRAGS 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1847698978 324 EDTDKVAKAIHEGTFKTPMGDLSFDEKGDLKNFKFVIYEWHFGKPKTEAN 373
Cdd:PRK15404 320 DDPAKVAKYLKANTFDTVIGPLSWDEKGDLKGFEFGVFEWHADGTKTAAK 369
|
|
| PBP1_ABC_LIVBP-like |
cd06342 |
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active ... |
31-363 |
8.62e-143 |
|
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.
Pssm-ID: 380565 [Multi-domain] Cd Length: 334 Bit Score: 408.45 E-value: 8.62e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVNDGVKFVVGHLCSSSTQ 110
Cdd:cd06342 1 KIGVAGPLTGPNAALGQDIRNGAELAVDEINAKGGGLGFKIELVAQDDACDPAQAVAAAQKLVADGVVAVIGHYNSGAAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 111 PASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKTLE 190
Cdd:cd06342 81 AAAPIYAEAGIPMISPSATNPKLTEQGYKNFFRVVGTDDQQGPAAADYAAKTLKAKRVAVIHDGTAYGKGLADAFKKALK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 191 DKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGASEG 270
Cdd:cd06342 161 ALGGTVVGREGITPGTTDFSALLTKIKAANPDAVYFGGYYPEAGLLLRQLREAGLKAPFMGGDGIVSPDFIKAAGDAAEG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 271 LLVTLP-QAFDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAIHEGTFKTPMGDLSFDE 349
Cdd:cd06342 241 VYATTPgAPPEKLPAAKAFLKAYKAKFGEPPGAYAAYAYDAAQVLLAAIEKAGSTDRAAVAAALRATDFDGVTGTISFDA 320
|
330
....*....|....
gi 1847698978 350 KGDLKNFKFVIYEW 363
Cdd:cd06342 321 KGDLTGPAFTVYQV 334
|
|
| LivK |
COG0683 |
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ... |
27-366 |
7.68e-94 |
|
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];
Pssm-ID: 440447 [Multi-domain] Cd Length: 314 Bit Score: 282.98 E-value: 7.68e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 27 ADTIKIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLC 105
Cdd:COG0683 1 ADPIKIGVLLPLTGPYAALGQPIKNGAELAVEEINAAGGVLGRKIELVVEDDASDPDTAVAAARKLIDqDKVDAIVGPLS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 106 SSSTQPASDIYEDEGIIMITPAATAPEIT-ARGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATA 184
Cdd:COG0683 81 SGVALAVAPVAEEAGVPLISPSATAPALTgPECSPYVFRTAPSDAQQAEALADYLAKKLGAKKVALLYDDYAYGQGLAAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 185 VKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFmgpegvgndsisqia 264
Cdd:COG0683 161 FKAALKAAGGEVVGEEYYPPGTTDFSAQLTKIKAAGPDAVFLAGYGGDAALFIKQAREAGLKGPL--------------- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 265 qgasegllvtlpqafdqlpeNKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAIHEGTFKTPMGD 344
Cdd:COG0683 226 --------------------NKAFVKAYKAKYGREPSSYAAAGYDAALLLAEAIEKAGSTDREAVRDALEGLKFDGVTGP 285
|
330 340
....*....|....*....|..
gi 1847698978 345 LSFDEKGDLKNfKFVIYEWHFG 366
Cdd:COG0683 286 ITFDPDGQGVQ-PVYIVQVKAD 306
|
|
| PBP1_ABC_HAAT-like |
cd06349 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-360 |
1.08e-84 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380572 [Multi-domain] Cd Length: 338 Bit Score: 260.58 E-value: 1.08e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLCSSST 109
Cdd:cd06349 1 KIGVSGPLTGDNAEYGQQFKNGVELAVDEINAAGGVNGRKLELVVYDDQGDPKEAVNIAQKFVsDDKVVAVIGDFSSSCS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITaRGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKTL 189
Cdd:cd06349 81 MAAAPIYEEAGLVQISPTASHPDFT-KGGDYVFRNSPTQAVEAPFLADYAVKKLGAKKIAIIYLNTDWGVSAADAFKKAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 190 EDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGASE 269
Cdd:cd06349 160 KALGGEIVATEAYLPGTKDFSAQITKIKNANPDAIYLAAYYNDAALIAKQARQLGWDVQIFGSSSLYSPEFIELAGDAAE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 270 GLLVTLP-QAFDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSeDTDKVAKAIHEGTFKTPM-GDLSF 347
Cdd:cd06349 240 GVYLSSPfFPESPDPEVKEFVKAYKAKYGEDPDDFAARAYDAVNILAEAIEKAGT-DREAIRDALANIKDFSGLtGTITF 318
|
330
....*....|....
gi 1847698978 348 DEKGD-LKNFKFVI 360
Cdd:cd06349 319 DENGDvLKSLTILV 332
|
|
| PBP1_ABC_ligand_binding-like |
cd19980 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-360 |
2.86e-84 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380635 [Multi-domain] Cd Length: 334 Bit Score: 259.46 E-value: 2.86e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSST 109
Cdd:cd19980 1 KIGVIAPLSGPVAALGQQVLNGAKLAVEEINAKGGVLGRKLELVVEDDKCPPAEGVAAAKKLITdDKVPAIIGAWCSSVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKTL 189
Cdd:cd19980 81 LAVMPVAERAKVPLVVEISSAPKITEGGNPYVFRLNPTNSMLAKAFAKYLADKGKPKKVAFLAENDDYGRGAAEAFKKAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 190 EDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGASE 269
Cdd:cd19980 161 KAKGVKVVATEYFDQGQTDFTTQLTKLKAANPDAIFVVAETEDGALILKQARELGLKQQLVGTGGTTSPDLIKLAGDAAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 270 GLLVTLPQAFD-QLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAIHEGT-FKTPMGDLSF 347
Cdd:cd19980 241 GVYGASIYAPTaDNPANKAFVAAYKKKYGEPPDKFAALGYDAVMVIAEAIKKAGSTDPEKIRAAALKKVdYKGPGGTIKF 320
|
330
....*....|...
gi 1847698978 348 DEKGDLKNFKFVI 360
Cdd:cd19980 321 DEKGQAHKNVVLV 333
|
|
| PBP1_ABC_LivK_ligand_binding-like |
cd06347 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-352 |
4.24e-84 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380570 [Multi-domain] Cd Length: 334 Bit Score: 259.01 E-value: 4.24e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSST 109
Cdd:cd06347 1 KIGVIGPLTGEAAAYGQPALNGAELAVDEINAAGGILGKKIELIVYDNKSDPTEAANAAQKLIDeDKVVAIIGPVTSSIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITArGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDK-QQYGEGIATAVKKT 188
Cdd:cd06347 81 LAAAPIAQKAKIPMITPSATNPLVTK-GGDYIFRACFTDPFQGAALAKFAYEELGAKKAAVLYDVsSDYSKGLAKAFKEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 189 LEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGAS 268
Cdd:cd06347 160 FEKLGGEIVAEETYTSGDTDFSAQLTKIKAANPDVIFLPGYYEEAALIIKQARELGITAPILGGDGWDSPELLELGGDAV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 269 EGLLVTLPQAFD-QLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAIHEGT-FKTPMGDLS 346
Cdd:cd06347 240 EGVYFTTHFSPDdPSPEVQEFVKAYKAKYGEPPNAFAALGYDAVMLLADAIKRAGSTDPEAIRDALAKTKdFEGVTGTIT 319
|
....*.
gi 1847698978 347 FDEKGD 352
Cdd:cd06347 320 FDPNGN 325
|
|
| PBP1_ABC_transporter_LIVBP-like |
cd06268 |
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the ... |
31-315 |
6.99e-79 |
|
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily; Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.
Pssm-ID: 380492 [Multi-domain] Cd Length: 298 Bit Score: 244.16 E-value: 6.99e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLCSSST 109
Cdd:cd06268 1 KIGVVVPLTGPYADYGEEILRGVALAVEEINAAGGINGRKLELVIADDQGDPETAVAVARKLVdDDKVLAVVGHYSSSVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKTL 189
Cdd:cd06268 81 LAAAPIYQEAGIPLISPGSTAPELTEGGGPYVFRTVPSDAMQAAALADYLAKKLKGKKVAILYDDYDYGKSLADAFKKAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 190 EDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGASE 269
Cdd:cd06268 161 KALGGEIVAEEDFPLGTTDFSAQLTKIKAAGPDVLFLAGYGADAANALKQARELGLKLPILGGDGLYSPELLKLGGEAAE 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1847698978 270 GLLVTLP-QAFDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIA 315
Cdd:cd06268 241 GVVVAVPwHPDSPDPPKQAFVKAYKKKYGGPPSWRAATAYDATQALA 287
|
|
| PBP1_ABC_transporter_GPCR_C-like |
cd04509 |
Family C of G-protein coupled receptors and their close homologs, the type 1 ... |
41-276 |
2.86e-75 |
|
Family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems; This CD includes members of the family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems. The family C GPCR includes glutamate/glycine-gated ion channels such as the NMDA receptor, G-protein-coupled receptors, metabotropic glutamate, GABA-B, calcium sensing, pheromone receptors, and atrial natriuretic peptide-guanylate cyclase receptors. The glutamate receptors that form cation-selective ion channels, iGluR, can be classified into three different subgroups according to their binding-affinity for the agonists NMDA (N-methyl-D-asparate), AMPA (alpha-amino-3-dihydro-5-methyl-3-oxo-4-isoxazolepropionic acid), and kainate. L-glutamate is a major neurotransmitter in the brain of vertebrates and acts through either mGluRs or iGluRs. mGluRs subunits possess seven transmembrane segments and a large N-terminal extracellular domain. ABC-type leucine-isoleucine-valine binding protein (LIVBP) is a bacterial periplasmic binding protein that has homology with the amino-terminal domain of the glutamate-receptor ion channels (iGluRs). The extracellular regions of iGluRs are made of two PBP-like domains in tandem, a LIVBP-like domain that constitutes the N terminus (included in this model) followed by a domain related to lysine-arginine-ornithine-binding protein (LAOBP) that belongs to the type 2 periplasmic binding fold protein superfamily. The uncharacterized periplasmic components of various ABC-type transport systems are also included in this family.
Pssm-ID: 380490 Cd Length: 306 Bit Score: 235.28 E-value: 2.86e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 41 PVTQYGDMQVAGAEMAVEQINAKG-GVNGKMLEAKVYDDACDPKQAVAVANKIVND-----------------------G 96
Cdd:cd04509 21 IVAQYGIQRFEAMEQALDDINADPnLLPNNTLGIVIYDDCCDPKQALEQSNKFVNDliqkdtsdvrctngeppvfvkpeG 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 97 VKFVVGHLCSSSTQPASDIYEDEGIIMITPAATAPEITA-RGYKLVFRTIGLDSAQGPAAGNYIADHVkPKTVAVLHDKQ 175
Cdd:cd04509 101 IKGVIGHLCSSVTIPVSNILELFGIPQITYAATAPELSDdRGYQLFLRVVPLDSDQAPAMADIVKEKV-WQYVSIVHDEG 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 176 QYGEGIATAVKKTLEDKGVKVAVFEGV--NAGDKDFAAIISKLKQAN-VDFVYYGGYHPELGLILRQAKEKGLNAKF--M 250
Cdd:cd04509 180 QYGEGGARAFQDGLKKGGLCIAFSDGItaGEKTKDFDRLVARLKKENnIRFVVYFGYHPEMGQILRAARRAGLVGKFqfM 259
|
250 260
....*....|....*....|....*..
gi 1847698978 251 GPEGVGNDSIS-QIAQGASEGLLVTLP 276
Cdd:cd04509 260 GSDGWANVSLSlNIAEESAEGLITIKP 286
|
|
| PBP1_ABC_ligand_binding-like |
cd19984 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-315 |
1.23e-72 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380639 [Multi-domain] Cd Length: 296 Bit Score: 228.26 E-value: 1.23e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANK-IVNDGVKFVVGHLCSSST 109
Cdd:cd19984 1 KIGVILPLTGDAASYGEDMKNGIELAVEEINAAGGINGKKIELIYEDSKCDPKKAVSAANKlINVDKVKAIIGGVCSSET 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITARGyKLVFRTIGLDSAQGPAAGNYIADHVKpKTVAVLHDKQQYGEGIATAVKKTL 189
Cdd:cd19984 81 LAIAPIAEQNKVVLISPGASSPEITKAG-DYIFRNYPSDAYQGKVLAEFAYNKLY-KKVAILYENNDYGVGLKDVFKKEF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 190 EDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGASE 269
Cdd:cd19984 159 EELGGKIVASESFEQGETDFRTQLTKIKAANPDAIFLPGYPKEGGLILKQAKELGIKAPILGSDGFEDPELLEIAGEAAE 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1847698978 270 GLLVTLPQAFDQL-PENKALADAFQAKKQDPTGPFVFPAYSAVEVIA 315
Cdd:cd19984 239 GVIFTYPAFDDSSeKKQKFFFYRYKEKYGKEPDIYAALAYDAVMILA 285
|
|
| PBP1_ABC_HAAT-like |
cd06344 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
32-361 |
4.96e-70 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380567 [Multi-domain] Cd Length: 332 Bit Score: 222.87 E-value: 4.96e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 32 IGIAGArtGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLCSSSTQ 110
Cdd:cd06344 2 IVIGVA--WPFAPDGDLFLEGVELAVEEINAAGGVLGRKIRLVEYDDEASVDKGLAIAQRFAdNPDVVAVIGHRSSYVAI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 111 PASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADHvKPKTVAVLHDKQQYGEGIATAVKKTLE 190
Cdd:cd06344 80 PASIIYERAGLLMLSPGATAPKLTQHGFKYIFRNIPSDEDIARQLARYAARQ-GYKRIVIYYDDDSYGKGLANAFEEEAR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 191 DKGVKVAVFEGVNAGDKDFAAIISKLKQA-NVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGASE 269
Cdd:cd06344 159 ELGITIVDRRSYSSDEEDFRRLLSKWKALdFFDAIFLAGSMPEGAEFIKQARELGIKVPIIGGDGLDSPELIEIAGKAAE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 270 GLLVtlPQAFD---QLPENKALADAFQAK-KQDPTgpfVFPA--YSAVEVIAKAIEQTKSEDTDKVAKAIHE-GTFKTPM 342
Cdd:cd06344 239 GVVV--ATVFDpddPRPEVRAFVEAFRKKyGREPD---VWAAqgYDAVKLLAEAIEKAGSTVPAKIASALRFlENWEGVT 313
|
330
....*....|....*....
gi 1847698978 343 GDLSFDEKGDLKNFKFVIY 361
Cdd:cd06344 314 GTYSFDANGDVVGKAIYFK 332
|
|
| PBP1_ABC_ligand_binding-like |
cd06338 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
31-363 |
3.67e-69 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380561 [Multi-domain] Cd Length: 347 Bit Score: 220.92 E-value: 3.67e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNG----KMLEAKVYDDACDPKQAVAVANK-IVNDGVKFVVGHLC 105
Cdd:cd06338 1 KIGASLSLTGPFAGEGKAQKRGYELWVEDVNAAGGVKGggkkRPVELVYYDDQSDPATAVRLYEKlITEDKVDLLLGPYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 106 SSSTQPASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADHV-KPKTVAVLHDKQQYGEGIATA 184
Cdd:cd06338 81 SGLTLAAAPVAEKYGIPMIAGGAASDSIFERGYKYVFGVLPPASDYAKGLLDLLAELGpKPKTVAIVYEDDPFGKEVAEG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 185 VKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPE-GVGNDSISQI 263
Cdd:cd06338 161 AREAAKKAGLEVVYDESYPPGTTDFSPLLTKVKAANPDILLVGGYPPDAITLVRQMKELGYNPKAFFLTvGPAFPAFREA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 264 AQGASEGLLVT---LPQA-FDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAIHEGTFK 339
Cdd:cd06338 241 LGKDAEGVLGPsqwEPSLpYKVFPGAKEFVKAYKEKFGEEPSYHAAAAYAAGQVLQQAIEKAGSLDPEKVRDALASLDFD 320
|
330 340
....*....|....*....|....
gi 1847698978 340 TPMGDLSFDEKGDLKNFKFVIYEW 363
Cdd:cd06338 321 TVYGPIKFDETGLQIGKPMVVVQW 344
|
|
| PBP1_ABC_HAAT-like |
cd19988 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-315 |
2.35e-67 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380643 [Multi-domain] Cd Length: 302 Bit Score: 214.83 E-value: 2.35e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSST 109
Cdd:cd19988 1 KIGVFGPLSGDAAPYGQAMLQGAELAVEEINAAGGILGIPIELVVEDDEGLPAASVSAAKKLIYqDKVWAIIGSINSSCT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKTL 189
Cdd:cd19988 81 LAAIRVALKAGVPQINPGSSAPTITESGNPWVFRCTPDDRQQAYALVDYAFEKLKVTKIAVLYVNDDYGRGGIDAFKDAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 190 EDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGASE 269
Cdd:cd19988 161 KKYGIEVVVEESYNRGDKDFSPQLEKIKDSGAQAIVMWGQYTEGALIAKQARELGLKQPLFGSDGLVTPKFIELAGDAAE 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1847698978 270 GllVTLPQAF---DQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIA 315
Cdd:cd19988 241 G--AIATTPFlpdSDDPKVSAFVEKYKKRYGEEPDVFAAQAYDAMNILA 287
|
|
| PBP1_ABC_ligand_binding-like |
cd06335 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
31-333 |
5.93e-65 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380558 [Multi-domain] Cd Length: 348 Bit Score: 210.16 E-value: 5.93e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLCSSST 109
Cdd:cd06335 1 KIGVIGPLTGPSAELGESARRGVELAVEEINAAGGILGRKIELVERDDEANPTKAVQNAQELIdKEKVVAIIGPTNSGVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEIT---ARGYKLVFRTIGLDSAQGPAAGNYIADHvKPKTVAVLHDKQQYGEGIATAVK 186
Cdd:cd06335 81 LATIPILQEAKIPLIIPVATGTAITkppAKPRNYIFRVAASDTLQADFLVDYAVKK-GFKKIAILHDTTGYGQGGLKDVE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 187 KTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQG 266
Cdd:cd06335 160 AALKKRGITPVATESFKIGDTDMTPQLLKAKDAGADVILVYGLGPDLAQILKAMEKLGWKVPLVGSWGLSMPNFIELAGP 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1847698978 267 ASEGLLVTLPQAFDQL-PENKALADAFQAK---KQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAI 333
Cdd:cd06335 240 LAEGTIMTQTFIEDYLtPRAKKFIDAYKKKygtDRIPSPVSAAQGYDAVYLLAAAIKQAGSTDGKKIRAAL 310
|
|
| PBP1_ABC_ligand_binding-like |
cd06340 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
31-363 |
1.10e-64 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380563 [Multi-domain] Cd Length: 352 Bit Score: 209.34 E-value: 1.10e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGG---VNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCS 106
Cdd:cd06340 1 KIGVLYPLSGPLALIGQEAKRGAELAVDEINAAGGiksLGGAKIELVVADTQSDPEVAASEAERLITqEGVVAIIGAYSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 107 SSTQPASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADH-----VKPKTVAVLHDKQQYGEGI 181
Cdd:cd06340 81 SVTLAASQVAERYGVPFVTASAVADEITERGFKYVFRTAPTASQFAEDAVDFLKELakkkgKKIKKVAIIYEDSAFGTSV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 182 ATAVKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAK-FMGPEGVGNDSI 260
Cdd:cd06340 161 AKGLKKAAKKAGLEVVLDEPYPAGATDLSSEVLKLKAAKPDVVFATSYTNDAILLLRTMKELGFKPKaIIGVGGGYSDPE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 261 SQIAQGA-SEGLLVTLPQAFDQ---LPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKA---- 332
Cdd:cd06340 241 FLKALGKdAEGVFSVVPWSPDLakkKPGAKEVNERYKKKYGEDMTGHAARAYTAAWVLADALERAGSTDPEAIRAAaalt 320
|
330 340 350
....*....|....*....|....*....|...
gi 1847698978 333 --IHEGTFkTPMGDLSFDEKGDLKNFKFVIYEW 363
Cdd:cd06340 321 ldIPEGLI-MPGGGVKFDEKGQNVLARPVVVQW 352
|
|
| PBP1_ABC_ligand_binding-like |
cd06346 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-352 |
2.12e-61 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380569 [Multi-domain] Cd Length: 314 Bit Score: 199.71 E-value: 2.12e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSST 109
Cdd:cd06346 1 KIGALLPLTGPLASLGPPMLAAAELAVEEINAAGGVLGKKVELVVEDSQTDPTAAVDAARKLVDvEGVPAIVGAASSGVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITA-RGYKLVFRTIGLDSAQGPAAGNYIADHvKPKTVAVLHDKQQYGEGIATAVKKT 188
Cdd:cd06346 81 LAVASVAVPNGVVQISPSSTSPALTTlEDKGYVFRTAPSDALQGVVLAQLAAER-GFKKVAVIYVNNDYGQGLADAFKKA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 189 LEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGL-NAKFMGPEGV-GNDSISQIAQG 266
Cdd:cd06346 160 FEALGGTVTASVPYEPGQTSYRAELAQAAAGGPDALVLIGYPEDGATILREALELGLdFTPWIGTDGLkSDDLVEAAGAE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 267 ASEGLLVTLPQAfDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAieqtksedtdkvakaiHEGTfktpMGDLS 346
Cdd:cd06346 240 ALEGMLGTAPGS-PGSPAYEAFAAAYKAEYGDDPGPFAANAYDAVMLLALA----------------YEGA----SGPID 298
|
....*.
gi 1847698978 347 FDEKGD 352
Cdd:cd06346 299 FDENGD 304
|
|
| PBP1_ABC_HAAT-like |
cd19981 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-321 |
3.41e-59 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380636 [Multi-domain] Cd Length: 297 Bit Score: 193.66 E-value: 3.41e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSST 109
Cdd:cd19981 1 KIGFFAPLTGPAAADGKSALHGAELAVEQINAAGGINGKKVELVVYDDQASPKQAVNIAQKLIEqDKVVAVVSGSYSGPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITARGyKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKTL 189
Cdd:cd19981 81 RAAAPIFQEAKVPMVSAYAVHPDITKAG-DYVFRVAFLGPVQGRAGAEYAVKDLGAKKVAILTIDNDFGKSLAAGFKEEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 190 EDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGASE 269
Cdd:cd19981 160 KKLGAEIVSEYAYALGDRDFRPILTKIKSANPDAIYASGYYAEAAPIVKQARELGIKVPIIGQEGYDSPKFIEIAGSAAE 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1847698978 270 GLLVTLP-QAFDQLPENKALADAFQAK-KQDPTGpFVFPAYSAVEVIAKAIEQT 321
Cdd:cd19981 240 GVIITTSlNRDSDRPITQKFIKEYRKRyGIDPDM-VAASTYDAVMVLAGEVQKP 292
|
|
| Peripla_BP_6 |
pfam13458 |
Periplasmic binding protein; This family includes a diverse range of periplasmic binding ... |
29-366 |
1.12e-58 |
|
Periplasmic binding protein; This family includes a diverse range of periplasmic binding proteins.
Pssm-ID: 433225 [Multi-domain] Cd Length: 342 Bit Score: 193.64 E-value: 1.12e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 29 TIKIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLCSS 107
Cdd:pfam13458 1 PIKIGVLTPLSGPYASSGKSSRAGARAAIEEINAAGGVNGRKIELVVADDQGDPDVAAAAARRLVdQDGVDAIVGGVSSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 108 STQPASDIYEDEGIIMITPAATAPEITARGyklVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKK 187
Cdd:pfam13458 81 VALAVAEVLAKKGVPVIGPAALTGEKCSPY---VFSLGPTYSAQATALGRYLAKELGGKKVALIGADYAFGRALAAAAKA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 188 TLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFM--GPEGVGNDSISQIAQ 265
Cdd:pfam13458 158 AAKAAGGEVVGEVRYPLGTTDFSSQVLQIKASGADAVLLANAGADTVNLLKQAREAGLDAKGIklVGLGGDEPDLKALGG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 266 GASEGLLVTLP-QAFDQLPENKALADAFQAK-KQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAIHEGTFKTPMG 343
Cdd:pfam13458 238 DAAEGVYATVPfFPDLDNPATRAFVAAFAAKyGEAPPTQFAAGGYIAADLLLAALEAAGSPTREAVIAALRALPYDGPFG 317
|
330 340
....*....|....*....|...
gi 1847698978 344 DLSFDEKGDLKNFKFVIYEWHFG 366
Cdd:pfam13458 318 PVGFRAEDHQAVHCMYLVQVKAD 340
|
|
| PBP1_ABC_HAAT-like |
cd19986 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-315 |
1.20e-58 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380641 [Multi-domain] Cd Length: 297 Bit Score: 192.07 E-value: 1.20e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVNDG-VKFVVGHLCSSST 109
Cdd:cd19986 1 KIGVVAPLTGPAALNGEYQKNGAQLALEEINAAGGVLGRPLELVVEDDQGTNTGAVNAVNKLISDDkVVAVIGPHYSTQV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITpAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKTL 189
Cdd:cd19986 81 LAVSPLVKEAKIPVIT-GGTSPKLTEQGNPYMFRIRPSDSVSAKALAKYAVEELGAKKIAILYDNDDFGTGGADVVTAAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 190 EDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGASE 269
Cdd:cd19986 160 KALGLEPVAVESYNTGDKDFTAQLLKLKNSGADVIIAWGHDAEAALIARQIRQLGLDVPVIGSSSFATPTVLLLAGEALE 239
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1847698978 270 GLL-VTLPQAFDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIA 315
Cdd:cd19986 240 GIYsVTDFVPSDPDPKVQAFVKKYKAKYGEDPDLYSAWYYDAMYLLA 286
|
|
| PBP1_ABC_ligand_binding-like |
cd06345 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-352 |
3.08e-58 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380568 [Multi-domain] Cd Length: 356 Bit Score: 192.87 E-value: 3.08e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTgpvTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANK-IVNDGVKFVVGHLCSSST 109
Cdd:cd06345 1 KIGVLGPLS---APAGEAMERGAELAVEEINAAGGILGRKVELVVADTQGKPEDGVAAAERlITEDKVDAIVGGFRSEVV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITAR------GYKLVFRTIGLDSAQGPAAGNYIADHV----KPKTVAVLHDKQQYGE 179
Cdd:cd06345 78 LAAMEVAAEYKVPFIVTGAASPAITKKvkkdyeKYKYVFRVGPNNSYLGATVAEFLKDLLveklGFKKVAILAEDAAWGR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 180 GIATAVKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVG-ND 258
Cdd:cd06345 158 GIAEALKKLLPEAGLEVVGVERFPTGTTDFTPILSKIKASGADVIVTIFSGPGGILLVKQWAELGVPAPLVGINVPAqDP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 259 SISQIAQGASEGLLVTLPQA--FDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAIHEG 336
Cdd:cd06345 238 EFWENTGGAGEYEITLAFAApkAKVTPKTKPFVDAYKKKYGEAPNYTAYTAYDAIYILAEAIERAGSTDPDALVKALEKT 317
|
330
....*....|....*.
gi 1847698978 337 TFKTPMGDLSFDEKGD 352
Cdd:cd06345 318 DYEGVRGRIKFDKKDE 333
|
|
| PBP1_ABC_ligand_binding-like |
cd06343 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
27-334 |
4.23e-58 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however its ligand specificity has not been determined experimentally.
Pssm-ID: 380566 [Multi-domain] Cd Length: 355 Bit Score: 192.40 E-value: 4.23e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 27 ADTIKIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLC 105
Cdd:cd06343 4 DDEIKIGTSLPLSGPAAAYGKPVRAGAAAYFDEVNAAGGINGRKIELIVEDDGYDPARAVAAVRKLVEqDKVFAIVGGLG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 106 SSSTQPASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAV 185
Cdd:cd06343 84 TPTNLAVRPYLNEAGVPQLFPATGASALSPPPKPYTFGVQPSYEDEGRILADYIVETLPAAKVAVLYQNDDFGKDGLEGL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 186 KKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDS-ISQIA 264
Cdd:cd06343 164 KEALKAYGLEVVAEETYEPGDTDFSSQVLKLKAAGADVVVLGTLPKEAAAALKEAAKLGWKPTFLGSSVSADPTtLAKAG 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1847698978 265 QGASEGLLVTL---PQAFDQLPENKALADAFQAK-KQDPTGPFVFPAYSAVEVIAKAIEQTKSEDT-DKVAKAIH 334
Cdd:cd06343 244 GDAAEGVYSASylkDPTDADDPAVKEFREAYKKYfPDDPPNAYALYGYAAAQVFVEALKRAGKDLTrEGLIKALE 318
|
|
| PBP1_As_SBP-like |
cd06330 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
31-351 |
1.26e-57 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea that is predicted to be involved in the efflux of toxic compounds. Members of this subgroup include proteins from Herminiimonas arsenicoxydans, which is resistant to arsenic (As) and various heavy metals such as cadmium and zinc. Moreover, they show significant sequence similarity to the cluster of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa.
Pssm-ID: 380553 [Multi-domain] Cd Length: 342 Bit Score: 190.85 E-value: 1.26e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSST 109
Cdd:cd06330 1 KIGVITPLSGAAAVYGEPARNGAELAVEEINAAGGILGRKIELVVRDDKGKPDEAVRAARELVLqEGVDFLIGTISSGVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITA-RGYKLVFRTIGLDSAQGPAAGNYIAD-HVKPKTVAVLHDKQQYGEGIATAVKK 187
Cdd:cd06330 81 LAVAPVAEELKVLFIATDAATDRLTEeNFNPYVFRTSPNTYMDAVAAALYAAKkPPDVKRWAGIGPDYEYGRDSWAAFKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 188 TLEDKGVKVAVFEGVNA--GDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQ 265
Cdd:cd06330 161 ALKKLKPDVEVVGELWPklGATDYTAYITALLAAKPDGVFSSLWGGDLVTFVKQAKPYGLFDKTKVVSGLGGGSEVLQAL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 266 GAS--EGLLVT--LPQAFDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAIHEGTFKTP 341
Cdd:cd06330 241 GKEmpEGLIGGgrYPFGWPDTPLNKAFVEAYRAKYGEYPTYWAYEAYAAVMALKAAIEKAGSTDTDKVIAALEGLTFDTP 320
|
330
....*....|
gi 1847698978 342 MGDLSFDEKG 351
Cdd:cd06330 321 GGKITIRAED 330
|
|
| PBP1_ABC_HAAT-like |
cd06348 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-352 |
1.06e-56 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380571 [Multi-domain] Cd Length: 342 Bit Score: 188.60 E-value: 1.06e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANK-IVNDGVKFVVGHLCSSST 109
Cdd:cd06348 1 KIGVALSLTGPGALYGQSQKNGAQLAVEEINAAGGVGGVKIELIVEDTAGDPEQAINAFQKlINQDKVLAILGPTLSSEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITARGyKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHD-KQQYGEGIATAVKKT 188
Cdd:cd06348 81 FAADPIAQQAKVPVVGISNTAPGITDIG-PYIFRNSLPEDKVIPPTVKAAKKKYGIKKVAVLYDqDDAFTVSGTKVFPAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 189 LEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGAS 268
Cdd:cd06348 160 LKKNGVEVLDTETFQTGDTDFSAQLTKIKALNPDAIVISALAQEGALIVKQARELGLKGPIVGGNGFNSPDLIKLAGKAA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 269 EGLLVTlpQAF---DQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKS-----EDTDKVAKAIHEGTFKT 340
Cdd:cd06348 240 EGVIVG--SAWspdNPDPKNQAFVAAYKEKYGKEPDQFAAQAYDAAYILAEAIKKAGSttdraDLRDALARILIAKDFEG 317
|
330
....*....|..
gi 1847698978 341 PMGDLSFDEKGD 352
Cdd:cd06348 318 PLGPFSFDADRD 329
|
|
| PBP1_ABC_RPA1789-like |
cd06333 |
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, ... |
31-333 |
3.02e-53 |
|
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, RPA1791-1793), involved in active transport of lignin-derived aromatic substrates, and its close homologs; This group includes RPA1789 (CouP) from Rhodopseudomonas palustris and its close homologs in other bacteria. RPA1789 (CouP) is the periplasmic binding-protein component of an ABC system (CouPSTU; RPA1789, RPA1791-1793) that is involved in the active transport of lignin-derived aromatic substrates. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380556 [Multi-domain] Cd Length: 342 Bit Score: 179.67 E-value: 3.02e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSST 109
Cdd:cd06333 1 KIGAILSLTGPAASLGIPERNAVELLVEQINAAGGINGRKLELIVYDDESDPTKAVTNARKLIEeDKVDAIIGPSTTGES 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPeITARGYKLVFRTIGLDSAQGPAAGNYIADHvKPKTVAVLHDKQQYGEGIATAVKKTL 189
Cdd:cd06333 81 LAVAPIAEEAKVPLISLAGAAA-IVEPVRKWVFKTPQSDSLVAEAILDYMKKK-GIKKVALLGDSDAYGQSGRAALKKLA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 190 EDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGASE 269
Cdd:cd06333 159 PEYGIEIVADERFARTDTDMTAQLTKIRAAKPDAVLVWASGPPAALVAKNLRQLGYKGPIYQSHGAANQDFIKLAGKAAE 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1847698978 270 GLLVTLPQ--AFDQLPEN-------KALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAI 333
Cdd:cd06333 239 GVILPAGKllVADQLPDSdpqkkvlLEFVKAYEAKYGEGPSTFAGHAYDALLLLVEAIEPAGGTDRAALRDAL 311
|
|
| PBP1_ABC_ligand_binding-like |
cd06336 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
31-333 |
7.58e-53 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380559 [Multi-domain] Cd Length: 345 Bit Score: 178.58 E-value: 7.58e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGG--VNGK--MLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLC 105
Cdd:cd06336 1 KIGFLGPLSGPAAAWGLPMLRGLELAADEINAAGGikVGGKkyKVEVVSYDDKYTPAEAVAAARRLVSqDGVKFIFGPGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 106 SSSTQPASDIYEDEGIIMITpAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAV 185
Cdd:cd06336 81 SAIAAAVQPVTERNKVLLLT-AAFSDPILGPDNPLLFRIPPTPYEYAPPFIKWLKKNGPIKTVALIAPNDATGKDWAAAF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 186 KKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHP-ELGLILRQAKEKGLNAKFMGPEGVGNDSISQIA 264
Cdd:cd06336 160 VAAWKAAGGEVVAEEFYDRGTTDFYPVLTKILALKPDALDLGGSSPgPAGLIIKQARELGFKGPFVSEGGAKADEILKEV 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1847698978 265 QG-ASEGLLVTLPQAFDQLPEN--KALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAI 333
Cdd:cd06336 240 GGeAAEGFIGVLPADDDPIASPgaKAFVERYKKKYGEPPNSESALFYDAAYILVKAMEKAGTVDDTKKIRAA 311
|
|
| PBP1_ABC_ligand_binding-like |
cd19982 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
31-315 |
4.50e-47 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380637 [Multi-domain] Cd Length: 302 Bit Score: 162.07 E-value: 4.50e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSST 109
Cdd:cd19982 1 KIGAILSLTGPFAPFGEMFKNGYEMALEEINAAGGIKGKKLELVIEDDQSKPQTALAAAEKLVSqDKVPLIVGGYSSGIT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKTL 189
Cdd:cd19982 81 LPVAAVAERQKIPLLVPTAADDDITKPGYKYVFRLNPPASIYAKALFDFFKELVKPKTIAILYENTAFGTSVAKAARRFA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 190 EDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAK-FMGpeGVGNDSISQIAQGA- 267
Cdd:cd19982 161 KKRGIEVVADESYDKGATDFKPLLNKVKAANPDVVYMVSYLNDAILLMRQAKELGLNPKlFAG--GGAGFTIPEFLKQAg 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1847698978 268 --SEGLLVTLPQAFD-QLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIA 315
Cdd:cd19982 239 plAEYVVTATLWSPDvKYPGAKEFYEKYKAKYGVEPSYHEAEAYAALYVAA 289
|
|
| PBP1_ABC_HAAT-like |
cd19985 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-315 |
4.56e-46 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380640 [Multi-domain] Cd Length: 321 Bit Score: 160.13 E-value: 4.56e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVNDGVKFVVGHLCSSSTQ 110
Cdd:cd19985 1 HIAVVGPMSGKSASKGKSMLRGAELYIDQINAAGGINGKKVKLDVFDDQNDPDAARKAAQIIVSDKALAVIGHYYSSASI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 111 PASDIYEDEGIIMITPAATAPEITaRGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKTLE 190
Cdd:cd19985 81 AAGKIYKKAGIPAITPSATADAVT-RDNPWYFRVIFNDSLQGRFLANYAKKVLKKDKVSIIYEEDSYGKSLASVFEATAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 191 DKGVKV----AVFEGVNAGDKDFAAIISKLKQA--NVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQI- 263
Cdd:cd19985 160 ALGLKVlkkwSFDTDSSQLDQNLDQIVDELKKApdEPGVIFLATHADEGAKLIKKLRDAGLKAPIIGPDSLASESFAQGf 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1847698978 264 ---------AQGASEGLLVTLPQAFDQLPEN-KALADAFQAKKQDPTGPFVFPAYSAVEVIA 315
Cdd:cd19985 240 aeypeekeePGYYTDGIYATSPFIFDIANEKaQKFRDTYQKRYGEEPSWIAAFAYDAAMLAI 301
|
|
| PBP1_AmiC-like |
cd06331 |
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system ... |
31-349 |
2.68e-41 |
|
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF); This group includes the type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF), found in bacteria and Archaea. AmiC controls expression of the amidase operon by a ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon is induced. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380554 [Multi-domain] Cd Length: 333 Bit Score: 147.75 E-value: 2.68e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSST 109
Cdd:cd06331 1 KIGLLTPLSGPASVYGRAIANGAELAVEEINAAGGVLGRPVELVVEDDASDPATAVAAARRLIQqDKVDAIVGPITSATR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITARgykLVFRTigldsaqGPAAGNYIADHVKP------KTVAVLHDKQQYGEGIAT 183
Cdd:cd06331 81 NAVAPVAERAKVPLLYPTFYEGGECSP---YLFCF-------GEVPNQQLDPLIPWlmeeygKKFYLIGSDYVWPRTMND 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 184 AVKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYY---GGYHPELgliLRQAKEKGLNAKFMGPEGVGNDSI 260
Cdd:cd06331 151 AARRVIEAHGGEVVGEEYLPLGTTDFSSVIEKIKASGADVVLStlvGADAVTF---LKQFAAAGLRRKVRIAALLFDENT 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 261 SQIAQG-ASEGLLVTLPqAFDQL--PENKALADAFQAKkqdpTGPFVFP-------AYSAVEVIAKAIEQTKSEDTDKVA 330
Cdd:cd06331 228 LAGLGAeAAEGIYSVLS-YFQSLdtPENKAFVAAYRKK----FGEDAPPitslseaAYEAVHLYAAAVEKAGSTDPEAVI 302
|
330
....*....|....*....
gi 1847698978 331 KAIHEGTFKTPMGDLSFDE 349
Cdd:cd06331 303 AALPGVSFDGPQGPVTMDP 321
|
|
| PBP1_SBP-like |
cd19989 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
31-315 |
1.13e-36 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380644 [Multi-domain] Cd Length: 299 Bit Score: 134.71 E-value: 1.13e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLCSSST 109
Cdd:cd19989 1 KIGVLTPLSGPYAALGEEARRGAQLAVEEINAAGGILGRPVELVVEDTEGKPATAVQKARKLVeQDGVDFLTGAVSSAVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEIT-ARGYKLVFRTIGLDSAQGPAAGNYIADhVKPKTVAVLHDKQQYGEGIATAVKKT 188
Cdd:cd19989 81 LAVAPKAAELKVPYLVTVAADDELTgENCNRYTFRVNTSDRMIARALAPWLAE-NGGKKWYIVYADYAWGQSSAEAFKEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 189 LEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAK---FMGPEGVGNDSISQIAQ 265
Cdd:cd19989 160 IEELGGEVVGTLFAPLGTTDFSSYITQISDSGADGLLLALAGSDAVNFLKQAGQFGLGKKykiVGGILSIEPLALPALGD 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1847698978 266 gASEGLLVTLPQAFD-QLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIA 315
Cdd:cd19989 240 -AAEGVYGGVRYPPTlDTPANRAFVEAYEKEYGEAPDNFAGEAYEAMQALA 289
|
|
| PBP1_aromatic_compounds-like |
cd06332 |
type 1 periplasmic binding proteins of active transport systems predicted to be involved in ... |
31-352 |
1.69e-35 |
|
type 1 periplasmic binding proteins of active transport systems predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; This group includes the type 1 periplasmic binding proteins of active transport systems that are predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; their substrate specificities are not well characterized, however. Members also exhibit close similarity to active transport systems for short chain amides and/or urea found in bacteria and archaea.
Pssm-ID: 380555 [Multi-domain] Cd Length: 336 Bit Score: 132.34 E-value: 1.69e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKggVNGKMLEAKVYDDACDPKQAVAVANK-IVNDGVKFVVGHLCSSST 109
Cdd:cd06332 1 KIGLLAPLTGPFAALGEDMVRGFELALEEVGGE--VAGRKVELVVEDDAGDPDTAVTKARKlVEQDKVDVLIGPLSGDEG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQ-GPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKT 188
Cdd:cd06332 79 LAVAPYAKEPGVPFINPVAGADDLTQRAKAPNFFRTSFTGSQwSAPLGDYAYKELGYKKVATIGSDYAFGYEQAAGFKRG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 189 LEDKGVKVA--VFegVNAGDKDFAAIISKLKQAnVDFVYYGGYHPELGLILRQAKEKGL--NAKFMGPEGVGNDSISqIA 264
Cdd:cd06332 159 FEAAGGEVVqeIW--VPLGTTDFSPYIAQIPSA-DDAVFAFLGGADAVRFLKQYREFGLkdKIPLIGGGTTVDESVL-PA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 265 QG-ASEGLLVTLPQAFD-QLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTK--SEDTDKVAKAIHEGTFKT 340
Cdd:cd06332 235 MGdAALGIISASHYAEGlDNPENKKFVAAYKKKFGKLPSLYAAGGYDGAQAILEALEAVGgdVSDKQALAAALRKVKFDS 314
|
330
....*....|..
gi 1847698978 341 PMGDLSFDEKGD 352
Cdd:cd06332 315 PRGPFSFDENRN 326
|
|
| ANF_receptor |
pfam01094 |
Receptor family ligand binding region; This family includes extracellular ligand binding ... |
53-364 |
2.12e-33 |
|
Receptor family ligand binding region; This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.
Pssm-ID: 460062 [Multi-domain] Cd Length: 347 Bit Score: 127.12 E-value: 2.12e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 53 AEMAVEQINAKGGVNGKM-LEAKVYDDACDPKQAVAVANKIVNDGVKFVVGHLCSSSTQPASDIYEDEGIIMITPAATAP 131
Cdd:pfam01094 6 VRLAVEDINADPGLLPGTkLEYIILDTCCDPSLALAAALDLLKGEVVAIIGPSCSSVASAVASLANEWKVPLISYGSTSP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 132 EITARG-YKLVFRTIGLDSAQGPAAGNyIADHVKPKTVAVLHDKQQYGEGIATAVKKTLEDKGVKVA--VFEGVNAGDKD 208
Cdd:pfam01094 86 ALSDLNrYPTFLRTTPSDTSQADAIVD-ILKHFGWKRVALIYSDDDYGESGLQALEDALRERGIRVAykAVIPPAQDDDE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 209 FAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAK---FMGPEGVGNDS--ISQIAQGASEGLLVTLPQAfdqlP 283
Cdd:pfam01094 165 IARKLLKEVKSRARVIVVCCSSETARRLLKAARELGMMGEgyvWIATDGLTTSLviLNPSTLEAAGGVLGFRLHP----P 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 284 ENKALADAFQAKKQD------PTGPFVF----PAYSAVEVIAKAIEQTKSED--------------TDKVAKAIHEGTFK 339
Cdd:pfam01094 241 DSPEFSEFFWEKLSDekelyeNLGGLPVsygaLAYDAVYLLAHALHNLLRDDkpgracgalgpwngGQKLLRYLKNVNFT 320
|
330 340
....*....|....*....|....*
gi 1847698978 340 TPMGDLSFDEKGDLKNFKFVIYEWH 364
Cdd:pfam01094 321 GLTGNVQFDENGDRINPDYDILNLN 345
|
|
| PBP1_SBP-like |
cd06329 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
31-346 |
1.15e-32 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380552 [Multi-domain] Cd Length: 343 Bit Score: 125.08 E-value: 1.15e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVNDGVKFVVGHLCSSSTQ 110
Cdd:cd06329 1 KIAFIDPLSGPFASVGEIYLKGLQFAIEEINAGGGLLGRKIELVPFDNKGSPQEALIQLKKAIDQGIRFVLQGNSSAVAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 111 PASDIYE-------DEGIIMITPAATAPEIT-ARGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIA 182
Cdd:cd06329 81 ALIDAIEkhnqrnpDKRVLFLNYGAEAPELTgAKCSFWHFRFDANADMKMAALADYMKKDGSIKKVYLINQDYSFGRDVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 183 TAVKKTLEDKGVKVAVfegvnAGD--------KDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEG 254
Cdd:cd06329 161 AAAKKNLKKKRPDIEI-----VGEdlhplgkvKDFSPYIAKIKASGADTVITGNWGNDLTLLMKAARDSGLKAPFYTYYA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 255 VGNDSISQIAQgASEGLLVTLPQAFDQL--PENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKA 332
Cdd:cd06329 236 DGPGAPAAIGE-AGVGRLVAVAYWHPNPktPELEKFAEAFRAKYGRYPDFNIGRTYMGVEMLAAAIKKAGSTDPEKVAKA 314
|
330
....*....|....
gi 1847698978 333 IHEGTFKTPMGDLS 346
Cdd:cd06329 315 LEGLSFDTPGGPVT 328
|
|
| PBP1_RPA0668_benzoate-like |
cd20014 |
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the ... |
31-349 |
5.08e-32 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380667 [Multi-domain] Cd Length: 346 Bit Score: 123.50 E-value: 5.08e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKggVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLCSSST 109
Cdd:cd20014 1 KIGLLLPYSGVYAALGEDIRNGFQLYLDEHGGK--LGGRPIELVKEDDEADPDVALQKARKLIeQDKVDVLVGPVSSGVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEIT-ARGYKLVFRTIGLDSAQGPAAGNYIADHVKpKTVAVLHDKQQYGEGIATAVKKT 188
Cdd:cd20014 79 LAIRDVVEQAKVPLIVANAGANALTrAACSPYIFRTSFSNWQLGYALGKYAAENVG-KTVVTIASDYAAGREVVAGFKEG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 189 LEDKGVKVAVFEGVNAGD-KDFAAIISKLKQANVDFVY--YGGyhPELGLILRQAKEKGLNAK--FMGPEGVGNDSISQI 263
Cdd:cd20014 158 FEAAGGKVVGEIWTPLGTtTDFSPYLTQIAASGPDAVYafFAG--ADAVRFVKQYAEFGLKGKipLYGPGFLTDEDVLPA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 264 AQGASEGLLVTLPQAfDQL--PENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSE--DTDKVAKAIHEGTFK 339
Cdd:cd20014 236 LGEAAEGIITVLHYA-PTLdnPANRAFVAAYQAKYGRLPDVYAVQGYDAAQVIDAALEAVGGDtsDKDILAAALELGSID 314
|
330
....*....|
gi 1847698978 340 TPMGDLSFDE 349
Cdd:cd20014 315 SPRGPFRFDP 324
|
|
| PBP1_SBP-like |
cd06328 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
31-347 |
1.04e-31 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative and gram-positive bacteria. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380551 [Multi-domain] Cd Length: 336 Bit Score: 122.41 E-value: 1.04e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQ-INAKGGVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLCSSS 108
Cdd:cd06328 1 KIGVITSLTGPLAAYGKQTERGFELGLEYaTDGTMEVDGRKIEVIVKDDQGDPDTAKAAATELIgDDGVDILVGTVSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 109 TQPASDIYEDEGIIMITPAATAPEITARGY-KLVFRTiGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKK 187
Cdd:cd06328 81 ALALAPVAEQNKKILIVGPAAADSITGENWnKYTFRT-SRNSWQDAIAGAKALADPLGKSVAFLAQDYAFGQDGVAAFKK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 188 TLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDF---VYYGGYHPELgliLRQAKEKGLNAKFMGPEGVGNdsISQIA 264
Cdd:cd06328 160 ALEAKGGKIVGEELVPVTTTDFTPYLQRILDAKPDVlfvAWAGTGALTL---WQQLADQGVLDDIKVVTGGPD--IATLA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 265 QGA-----SEGLLVTLPQAFDQlPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKS-EDTDKVAKAIHEGTF 338
Cdd:cd06328 235 ALGdalpgIEGLTYYYYGLPKN-PVNDWLVKAHKERYNAPPDLFTAGGFAAAQAVVRALEKAGGdTDVEKLIAALEGLTF 313
|
....*....
gi 1847698978 339 KTPMGDLSF 347
Cdd:cd06328 314 ETPKGKMTI 322
|
|
| PBP1_ABC_HAAT-like |
cd19983 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-315 |
3.14e-29 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380638 [Multi-domain] Cd Length: 303 Bit Score: 114.60 E-value: 3.14e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGpvtQYGDMQVA---GAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVNDGVKFVVGHLCSS 107
Cdd:cd19983 1 RIGFVGGLTG---RYSDLGVQgrnGAQLAVEEINAAGGINGRPVELIIRDDQQDPEAAKAADRELIAGGVVAIIGHMTSA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 108 STQPASDIYEDEGIIMITPAATAPEITARGYKLvFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDK--QQYGEGIATAV 185
Cdd:cd19983 78 MTVAVLPVINEAKVLMISPTVSTPELSGKDDYF-FRVTPTTRESAQALARYAYNRGGLRRVAVIYDLsnRAYSESWLDNF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 186 KKTLEDKGVKVAVFEGVNAG-DKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIA 264
Cdd:cd19983 157 RSEFEALGGRIVAEIPFSSGaDVDFSDLARRLLASKPDGLLLVASAVDTAMLAQQIRKLGSKIPLFSSAWAATEELLELG 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1847698978 265 QGASEGLLVtlPQAFD---QLPENKALADAFQAK-KQDPTGPFVFpAYSAVEVIA 315
Cdd:cd19983 237 GKAVEGMLF--SQAYDrnsSNPRYLAFKEAYEERfGREPSFAAAY-AYEAAMVLA 288
|
|
| PBP1_AmiC |
cd06357 |
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding ... |
31-350 |
5.67e-29 |
|
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family; This group includes the periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family. AmiC controls expression of the amidase operon by the ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon are induced.
Pssm-ID: 380580 [Multi-domain] Cd Length: 357 Bit Score: 115.37 E-value: 5.67e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANK-IVNDGVKFVVGhLCSSST 109
Cdd:cd06357 1 RVGLLFSQTGVTAIIEQSMLNGALLAIEEINAAGGVNGRPIEPVVYDPASDPDRYRELAERlLLEDGVRHIFG-CYTSAS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPAsdiyedegiiMItpaataPEITARGYKLVFRTI--GLDSAQ-----GPAA-------GNYIADHVKPKtVAVLHDKQ 175
Cdd:cd06357 80 RKA----------VL------PVVERHNALLWYPTPyeGFEYSPnviytGAVPnqhllplARYLLAHFGKR-VFLVGSNY 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 176 QYGEGIATAVKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYY-----GGYHpelglILRQAKEKGLNAKFM 250
Cdd:cd06357 143 VYPWESNRVARELIEASGGEVVGERYVPLGDTDFAEIIEEIKSLKPDVVFStlvgdSIYA-----FYRAYAEAGLDPADM 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 251 gP-------EGvgndSISQIAQGASEGLLVTLP--QAFDQlPENKALADAFQAK--KQDPTGPFVFPAYSAVEVIAKAIE 319
Cdd:cd06357 218 -PiaslttsEA----EVAAIGAEAAAGHYTSAPyfQSIDT-PENRAFVEAYRARfgDDAVTSAVAEAAYFQVHLLARAIE 291
|
330 340 350
....*....|....*....|....*....|.
gi 1847698978 320 QTKSEDTDKVAKAIHEGTFKTPMGDLSFDEK 350
Cdd:cd06357 292 RAGSDDPEAIRAALYGQEFDAPQGPVRIDPD 322
|
|
| PBP1_alkylbenzenes-like |
cd06360 |
type 1 periplasmic binding component of active transport systems predicted be involved in ... |
31-351 |
1.21e-28 |
|
type 1 periplasmic binding component of active transport systems predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; This group includes the type 1 periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; their substrate specificity is not well characterized, however.
Pssm-ID: 380583 [Multi-domain] Cd Length: 357 Bit Score: 114.31 E-value: 1.21e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKggVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLCSSST 109
Cdd:cd06360 1 KIGVLLPLTGPLAVNGEDVRDGFELYFDEIGNQ--VAGRKIELIVEDDEGKPDVGLTKARKLVeRDKVHVLAGIVSSAVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAATAPEIT-ARGYKLVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKT 188
Cdd:cd06360 79 YAVRDYVVEQKIPLVISNAGAAPLTqELASPYIFRTSFSNGQYDAPFGQYAYEKLGYRRIAVMASDYAAGHEQAGAFART 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 189 LEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKF--MGPEGVGNDSISQIAQG 266
Cdd:cd06360 159 FKQAGGKVVQEIYPPLGTADFAPYLARIQQDAADAVWAFFAGADAIRFVKQYDEYGLKGKLplVGIGGLVDDAILPEQGD 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 267 ASEGLLVTLP-QAFDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKS--EDTDKVAKAIHEGTFKTPMG 343
Cdd:cd06360 239 AALGIVSYLHySAALDTPENKAFVQAYRKKYGRDPGLYAEGGYVAARAIAEALEAVKGnvEDKEAFLEALRKVRFEAPRG 318
|
....*...
gi 1847698978 344 DLSFDEKG 351
Cdd:cd06360 319 PFRFDPYQ 326
|
|
| PBP1_ABC_ligand_binding-like |
cd19978 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
30-348 |
4.17e-26 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380633 [Multi-domain] Cd Length: 341 Bit Score: 106.89 E-value: 4.17e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 30 IKIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSS 108
Cdd:cd19978 1 IRLGMSAALSGPAAELGNEMKRGIEAAFNEVNAQGGVNGRKIKLIALDDGYEPDRTVKNTKKLIEeDKVFALIGYVGTPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 109 TQPASDIYEDEGIIMITPAATAPEITARGYKLVF--RTIGLDSAQgpAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVK 186
Cdd:cd19978 81 ALAALPLANEKKIPLFGPFTGAEFLRTPFLPYVFnlRASYADETE--ALVDYLVKTLGPKRIAIFYQNDAFGLAGLEGAK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 187 KTLEDKGVKVaVFEGV-NAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQ 265
Cdd:cd19978 159 KALKKRGLTP-VAEGSyTRNTLDVEEALAKILKAKPEAIILVGTYAPAAEFIRLARAAGLNPLFANVSFVGSEALALELG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 266 GASEGLLVT--LPQAFD-QLPenkaLADAFQA--KKQDPTGP--FV-FPAYSAVEVIAKAIEQTKSEDTDKVAKAIHEGT 337
Cdd:cd19978 238 DYGEGVIVSqvVPDPNDsSLP----IVKEYREamKKYGPNAPpdFVsLEGYLAARLLVEALKKAGPPLTREKLLALEESL 313
|
330
....*....|.
gi 1847698978 338 FKTPMGDLSFD 348
Cdd:cd19978 314 KNDLGKGLTLT 324
|
|
| PBP1_ABC_ligand_binding-like |
cd06334 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
31-322 |
1.15e-25 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380557 [Multi-domain] Cd Length: 360 Bit Score: 106.17 E-value: 1.15e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSST 109
Cdd:cd06334 1 KIGLLTDLTGPTADVGKPYAQGVRDYLNYVNEEGGINGVKIELEECDTGYKVPRAVACYKRLKAqDGVVAILGWGTGDTE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEgiIMITPAATAPEITARG--YKLVFRTIGLDSAQGPAAGNYIADHV----KPKTVAVLHDKQQYGEGIAT 183
Cdd:cd06334 81 ALAPRVAKDK--IPYISASYGRSLADDGkvFPYNFFVGATYSSQARALLKYIAQEWggklKGPKVAFVYHDSPFGREPIP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 184 AVKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQI 263
Cdd:cd06334 159 ALKAYAKELGFEVVAEQVPSPGALDATAQWLRIRRAGPDYVIIQGTGGSVAVIIKDAKRLGLKTKFIGNIWGGDEDLIKL 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1847698978 264 AQGASEGLLVTLPQAF-DQLPENKALADAFQAKKQDPTGPF---------VFPAYSAVEVIAKAIEQTK 322
Cdd:cd06334 239 AGDAAEGYVGVSPFAFgTDDPPGKEIVEEVAKKGKGDGPEEvgtvyynrgWATAMLAVEAIRRADKAGG 307
|
|
| Peripla_BP_5 |
pfam13433 |
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic ... |
30-350 |
2.84e-23 |
|
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic binding proteins.
Pssm-ID: 463875 [Multi-domain] Cd Length: 363 Bit Score: 99.59 E-value: 2.84e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 30 IKIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANK-IVNDGVKFVVGHLCSSS 108
Cdd:pfam13433 1 IKVGVLHSLTGTMAISERSLKDATLMAIEEINAAGGVLGRKIEPVVVDPASDWPLFAEKARKlIDQDKVRVVFGCWTSAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 109 TQPASDIYEDEGIIMITPAATAPEITARGyklVFRTIGLDSAQGPAAGNYIADHVKPKTVAVLHDkQQYGEGIATAVKKT 188
Cdd:pfam13433 81 RKAVLPVFERHNGLLFYPVQYEGFESSRN---IFYTGAAPNQQAIPAVDYLLSELGKRFFLVGSD-YVYPRTTNRILRAY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 189 LEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVY---YGGYHPELgliLRQAKEKGLNAKFMgP---EGVGNDSISQ 262
Cdd:pfam13433 157 LKAKGGEVVGERYLPLGSSDWQSIVAKIKAAGPDVVFstiNGDSNVAF---YRALRAAGITAEDI-PvmsFSVAEEELAG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 263 IAQGASEGLLVTLP--QAFDQlPENKALADAFQAKKQDP---TGPFVfPAYSAVEVIAKAIEQTKSEDTDKVAKAIHEGT 337
Cdd:pfam13433 233 MGPEPLVGHLAAWNyfQSLDT-PENKAFVAAFKARYGDDrvtNDPME-AAYIGVHLWAQAVEKAGTDDPDAVRQAMLGQE 310
|
330
....*....|...
gi 1847698978 338 FKTPMGDLSFDEK 350
Cdd:pfam13433 311 FDAPQGPVKIDPE 323
|
|
| PBP1_amide_urea_BP-like |
cd06356 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
31-350 |
1.28e-22 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the type 1 periplasmic-binding proteins that are predicted to have a function similar to that of an active transport system for short chain amides and/or urea in bacteria and Archaea, by sequence comparison and phylogenetic analysis.
Pssm-ID: 380579 [Multi-domain] Cd Length: 334 Bit Score: 96.99 E-value: 1.28e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLCSSST 109
Cdd:cd06356 1 KIGSIFDLSGGLNIYGKPMVHAMKLAVEEINAAGGLLGRQIELVAYDTQSDMQKYTQYAQQLIlRDKVDVVFGGITSASR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAAtapeitargY------KLVFRTiGLDSAQGPA-AGNYIADHVKPKtVAVLHDKQQYGEGIA 182
Cdd:cd06356 81 EAIRPILRRNKILYFYNTQ---------YeggvcdKNTFCT-GSTPEQQVSpLIEWAIKKYGKK-VYIIAADYNFGQISA 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 183 TAVKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYY---GGYHPELgliLRQAKEKGLNAKFMGPE---GVG 256
Cdd:cd06356 150 DWVKKYAKKNGGEVVGEEFFPLDVTDFGPTIQKIQAAKPDFVVSllvGGNHISF---YRQWAAAGLKKKIPIVStvfGAG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 257 NDSIsQIAQGASEGLLVTlPQAFDQL--PENKALADAFQAK--KQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKA 332
Cdd:cd06356 227 NEHK-VLSPPELEGMYVS-YSYFEELdtPANKAFVAKWRAKygDEPYINQEAVGVYNAVYLWAEAVEKAGSTEREAVIAA 304
|
330
....*....|....*....
gi 1847698978 333 IHEG-TFKTPMGDLSFDEK 350
Cdd:cd06356 305 LESGiSFDGPSGTVTVDPK 323
|
|
| PBP1_ABC_ligand_binding-like |
cd06326 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
30-274 |
3.54e-21 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380549 [Multi-domain] Cd Length: 339 Bit Score: 92.99 E-value: 3.54e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 30 IKIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLCSSS 108
Cdd:cd06326 1 IVIGQSAPLSGPLAELGREYLAGAKAYFDQVNAAGGINGRKIRLVTLDDGYDPARTVENTRQLIeQDKVVALFGYVGTAN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 109 TQPASDIYEDEGIIMITPAATAPEITARGYKLVFRTIGLDSAQgpaaGNYIADHVKP---KTVAVLHDKQQYGEGIATAV 185
Cdd:cd06326 81 VEAVLPLLEEAGVPLVGPLTGADSLREPGNPYVFHVRASYADE----VEKIVRHLATlglKRIAVVYQDDPFGKEGLAAA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 186 KKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQ 265
Cdd:cd06326 157 EAALAARGLEPVATAAVARNAADVAAAAAALAAAKPQAVVLIAAGKAAAAFIKALRAAGGAAQFYGLSVVGAAALAKALG 236
|
....*....
gi 1847698978 266 GASEGLLVT 274
Cdd:cd06326 237 DAARGVVVS 245
|
|
| PBP1_FmdD-like |
cd06355 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
31-350 |
7.91e-21 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF), found in Methylophilus methylotrophus, and its homologs from other bacteria. FmdD, a type 1 periplasmic binding protein, is induced by short-chain amides and urea and repressed by excess ammonia, while FmdE and FmdF are hydrophobic transmembrane proteins. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380578 [Multi-domain] Cd Length: 347 Bit Score: 92.25 E-value: 7.91e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANK-IVNDGVKFVVGHLCSSST 109
Cdd:cd06355 1 KVGILHSLSGTMAISERPLVDATLLAIDEINAAGGLLGRKIEPVIEDGASDWPTFAEKAEKlITQDKVAVIFGCWTSASR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAA-----TAPEItargyklvFRTIGLDSAQGPAAGNYIADHVKPKtVAVLHDKQQYGEGIATA 184
Cdd:cd06355 81 KAVLPVIEKYNGLLFYPVQyegleQSPNI--------VYTGATPNQQILPAIDWLLENLGKR-FFLVGSDYVFPRTANKI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 185 VKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVY---YGGYHPELgliLRQAKEKGLNAKFMgPE---GVGND 258
Cdd:cd06355 152 IRDQLKALGGEVVGEEYVPLGGTDFDAIVAKIKAFKPDVIVntlNGDSNIAF---FKQLAAAGITASDL-PVlsfSVSEA 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 259 SISQIAQGASEGLLVTLP--QAFDqLPENKALADAFQAK--KQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAIH 334
Cdd:cd06355 228 ELRAIGPEELAGHYAAWNyfQSLD-TPENQAFVEAFKAKygADRVTSDPMEAAYLGVYLWAQAVEKAGSFDPDAVRAALK 306
|
330
....*....|....*.
gi 1847698978 335 EGTFKTPMGDLSFDEK 350
Cdd:cd06355 307 GQSFEAPGGTVTVDPE 322
|
|
| PBP1_ABC_ligand_binding-like |
cd19979 |
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes ... |
31-341 |
4.60e-20 |
|
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380634 [Multi-domain] Cd Length: 350 Bit Score: 89.98 E-value: 4.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVNDgvKFVVGHLCSSSTQ 110
Cdd:cd19979 1 VIGLDADLSGGSAASGEAIKRGIQLAIDEINAAGGLLGRKLELVAKDHRGNPARGVDNLREFAAD--PDVLAVFGGLHSP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 111 PASDIYED---EGIIMITPAATAPEITARGYKL--VFRtIGLDSAQgpaAGNYIADH---VKPKTVAVLHDKQQYGEGIA 182
Cdd:cd19979 79 VLLAELDFiheLKIPYLVPWAAATPITRNGYSPnyIFR-LSVDDSL---AGPFLVEYalkKGCKRPALLLENTGWGRSNL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 183 TAVKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQ 262
Cdd:cd19979 155 KAMTKALAKKGLQPVGVEWFNWGDTDAKPQLRALKAAGADAILLVANAPEGAAIVKALAALPERLPIISHWGITGGDFPE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 263 IAQGASEGLLVTLPQ--AFDQLPENKALADAFQAKKQD------------PTGpfVFPAYSAVEVIAKAIEQTKSEDTDK 328
Cdd:cd19979 235 LPREALSKIDLRFIQtfSFFDANQSPRGKQVLARYKRRypvedpesdipaPVG--FAHAYDLTHLLALAIEQAGSTDRAA 312
|
330 340
....*....|....*....|.
gi 1847698978 329 VAKAI-----HEG---TFKTP 341
Cdd:cd19979 313 VRAALellppHEGlikTYKPP 333
|
|
| PBP1_Nba-like |
cd06359 |
type 1 periplasmic binding component of active transport systems predicted to be involved in ... |
31-348 |
2.66e-19 |
|
type 1 periplasmic binding component of active transport systems predicted to be involved in 2-nitrobenzoic acid degradation pathway; This group includes the type 1 periplasmic binding component of active transport systems that are predicted to be involved in 2-nitrobenzoic acid degradation pathway; their substrate specificities are not well characterized.
Pssm-ID: 380582 [Multi-domain] Cd Length: 333 Bit Score: 87.69 E-value: 2.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAK-GGVNGKMLEAkvyDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSS 108
Cdd:cd06359 1 KIGFITTLSGPAAVLGQDMRDGFNLALEQLGGKlGGLPVEVVVE---DDQLKPDVAKQAAERLIErDKVDFVTGIIFSNV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 109 TQPASDIYEDEGIIMITPAATAPEITARG-YKLVFRTIGLDSAQGPAAGNYIADHvKPKTVAVLHDKQQYGEGIATAVKK 187
Cdd:cd06359 78 MLAVVKPVVDSKVFYISANAGPSDLAGKGcNPNFFVTSWQNDQLHEAAGKYANDK-GYKRVYLLAPNYQAGKDALAGFKR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 188 TLEDKGVKVAVfegVNAGDKDFAAIISKLKQANVDFVYYggYHP-ELGL-ILRQAKEKGLNAK--FMGPeGVGNDSISQI 263
Cdd:cd06359 157 TYKGEVVGEIY---TPLGQLDFSAELAQIRAAKPDAVFA--FYPgGMGVnFVKQYAQAGLKKKipLYTV-GTLDDEDLLP 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 264 AQG-ASEGLLVTlPQAFDQL--PENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDK--VAKAIHEGTF 338
Cdd:cd06359 231 AMGdAALGVLSV-SQWSPDLdnPENKRFVAAFRKKYGRPPSNYAAQGYDAALLIDAAVKAVGGDLSDKdaLRAALRKADF 309
|
330
....*....|
gi 1847698978 339 KTPMGDLSFD 348
Cdd:cd06359 310 KSVRGAFRFN 319
|
|
| PBP1_SBP-like |
cd20378 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
31-371 |
6.69e-19 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380668 [Multi-domain] Cd Length: 357 Bit Score: 87.01 E-value: 6.69e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQinaKGGVNGKMLEAKVYDDACDPKQAVAVANKIVN-DGVKFVVGHLCSSST 109
Cdd:cd20378 1 TLGGLVSMSGAFAAAGKLADRGMRLAVEE---YGGALGRPLKYITRDTEGKPGTGVRKVQEAIAqDGARFFIGGTLSSVA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 110 QPASDIYEDEGIIMITPAAtAPEIT-ARGYKLVFRTigldsaQGPAAG-------NYIADHVKPKTVAVLHDKQQYGEGI 181
Cdd:cd20378 78 LAVSEEAEKAGGVYITSGG-ADEITgSRCNRSTFRW------SVPTYGairqtvrPVIKAMPKAKRWYTITPQYVFGESL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 182 ATAVKKTLEDKGvkvavFEGVNA-----GDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGL--NAKFMGPEG 254
Cdd:cd20378 151 LKNAKEVLKEKG-----IEHVGNsyhslGEREFSGYLTKAMAARPDVLLILNFGSQAVDALRQAVSFGLkrKMKILVAWS 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 255 VGNDSISQIAQGASEGLLVTLpQAFDQL--PENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKA 332
Cdd:cd20378 226 SGLDQFQELGPDICEGVYFGA-QYWHDVdtPANKALVKVYQAKFKETPSYALAAGYACTRMLLDAIDKAGSTDPAAVIKA 304
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1847698978 333 IHEGTFKTPMGDLSFDeKGD---LKNFKFVIyewhfGKPKTE 371
Cdd:cd20378 305 LEGLKYDGITGDEEVR-AADhqvLKPYYLLR-----GKAKAA 340
|
|
| PBP1_SBP-like |
cd19987 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
31-344 |
7.72e-19 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380642 [Multi-domain] Cd Length: 353 Bit Score: 86.61 E-value: 7.72e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKG------------GVNGKMLEAKVYDDACDPKQAVAVANK-IVNDGV 97
Cdd:cd19987 1 TIGLNVPLSGPYAPQGEDQRRGFELAVDHLNNGGglvdkdsrlsgdGILGKKVELVTADTETKADTAVDNAKRlIEQDGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 98 KFVVGHLCSSSTQPASDIYEDEGIIMITPAATAPEITAR-GYKLVFRTI--GLDSAQgpAAGNYIADHV-KPKTVAVLHD 173
Cdd:cd19987 81 VMITGGSSSAVAVAAQKLAQKEGVLYFAGLSHSNDTTGKdCHRYGFRECfnAHMSAK--ALAPYLVEKFgKDRKYFYLTA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 174 KQQYGEGIATAVKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFmgpE 253
Cdd:cd19987 159 DYTWGHSTEQSMREYTEAHGWKTVGNPATPLGETDFSAALLNAADSGADVLVLVLFGRDMVNALKQAKQFGLLKKM---D 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 254 GVGNDSISQIAQGAS----EGLLVTL---PQAFDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDT 326
Cdd:cd19987 236 IVVPLLTAFMAESVGpeimEGVLGTVnwhWSLPDDYSYAFGKAEAFEKEYGAYPSQAAASAYVQVLQYAAAVERAGSFDP 315
|
330
....*....|....*...
gi 1847698978 327 DKVAKAIHEGTFKTPMGD 344
Cdd:cd19987 316 PAVIRALEGHEYTLLKGE 333
|
|
| PBP1_RPA0985_benzoate-like |
cd20013 |
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the ... |
31-348 |
1.03e-17 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0985 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0985 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380666 [Multi-domain] Cd Length: 356 Bit Score: 83.46 E-value: 1.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKggVNGKMLEAKVYDDA-CDPKQAVAVANK-IVNDGVKFVVGHLCSSS 108
Cdd:cd20013 1 KVGVIGPFSGPFADYGKQFDRGIDLYLKLHGDK--VGGRKVEVIYRDDGgPNPAVAKRLAQElIVRDKVQILIGFGFTPN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 109 TQPASDIYEDEGIIMITPAATAPEITARGYKLVfRTiGLDSAQ-GPAAGNYIADHVKPKTVAVLHDkqqYGEGI--ATAV 185
Cdd:cd20013 79 ALAVAPVATEAKTPTVIMNAATSSITRKSPYFV-RT-SFTMWQvAYPMGKWAAKNGIKKAYTAVAD---YAPGHdaETAF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 186 KKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVD--FVYYGGYHPELGLiLRQAKEKGLNA---KFMGPEGVGNDSI 260
Cdd:cd20013 154 KKAFEAAGGKIVGSIRVPLATPDFAPFMQRIKDAKPDavFVFVPAGAPSIGF-LKAYAERGLKEagiKLLGTGDATDDDD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 261 SQIAQGASEGLLVTLP-QAFDQLPENKALADAFQAKKQDPTGPFVFP--AYSAVEVIAKAIEQTK-SEDTDKVAKAIHEG 336
Cdd:cd20013 233 LPAMGDAALGLITAGHySAALDSPENKAFVAAYQKAYGPDARPDFMAvaAYDGMALIYKMIKATGgKFDGDKAMAAVKGL 312
|
330
....*....|..
gi 1847698978 337 TFKTPMGDLSFD 348
Cdd:cd20013 313 KWESPRGPISID 324
|
|
| PBP1_ABC_ligand_binding-like |
cd06341 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
51-327 |
1.46e-17 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380564 [Multi-domain] Cd Length: 340 Bit Score: 82.74 E-value: 1.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 51 AGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGhlcSSSTQPAS--DIYEDEGIIMITPA 127
Cdd:cd06341 21 AGAEARFGLANAAGGINGRKVEYVWCDDQSDPATNLQAARQLVeDEKVFALVG---SSSAASGSanDYLAQAGIPVVGGA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 128 ATAPEITARGYKLVFRTIGLDSAQgpAAGNYIADHVKPKTVAVLHDKQQYGEGIATAVKKTLEDKGVKVAVFEGVNAGDK 207
Cdd:cd06341 98 GVSVWCFRNMFSNFFSLGGGGSTT--TYGQYAAALGGTKAAVVVTDIPAASQQLAQQLAASLRAAGVEVVGTAPYAAAAP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 208 DFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAKFMGPEGVGNDSISQIAQGASEGLLVTLPQA--FDQLPEN 285
Cdd:cd06341 176 DYTAVAQAAKAAGADAVVGVLDPDVAARVLKAARAQGLDLKVALSPSGYDPSVLAAYGAALAGVSVASTFLpfEADTPAV 255
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1847698978 286 KALADA---FQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTD 327
Cdd:cd06341 256 KAYRAAmakYAPELQDPLQQFALSGYIAADLFVRGLEAAGGCPTR 300
|
|
| PBP1_GPCR_family_C-like |
cd06350 |
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory ... |
40-277 |
1.63e-13 |
|
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate; categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (m; Ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate and are categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs). The metabotropic glutamate receptors (mGluR) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. The mGluRs are coupled to G proteins and are thus distinct from the iGluRs which internally contain ligand-gated ion channels. The mGluR structure is divided into three regions: the extracellular region, the seven-spanning transmembrane region and the cytoplasmic region. The extracellular region is further divided into the ligand-binding domain (LBD) and the cysteine-rich domain. The LBD has sequence similarity to the LIVBP, which is a bacterial periplasmic protein (PBP), as well as to the extracellular region of both iGluR and the gamma-aminobutyric acid (GABA)b receptor. iGluRs are divided into three main subtypes based on pharmacological profile: NMDA, AMPA, and kainate receptors. All family C GPCRs have a large extracellular N terminus that contain a domain with homology to bacterial periplasmic amino acid-binding proteins.
Pssm-ID: 380573 Cd Length: 350 Bit Score: 70.79 E-value: 1.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 40 GPVTQYGDMQVAGAEMAVEQINAKGGVNGKM---LEAKvydDACD-PKQAVAVA-----------------NKIVNDGVK 98
Cdd:cd06350 20 GILNPRGVQLVEAMIYAIEEINNDSSLLPNVtlgYDIR---DTCSsSSVALESSleflldngikllansngQNIGPPNIV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 99 FVVGHLCSSSTQPASDIYEDEGIIMITPAATAPEITARG-YKLVFRTIGLDSAQGPAagnyIAD---HVKPKTVAVLHDK 174
Cdd:cd06350 97 AVIGAASSSVSIAVANLLGLFKIPQISYASTSPELSDKIrYPYFLRTVPSDTLQAKA----IADllkHFNWNYVSTVYSD 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 175 QQYGEGIATAVKKTLEDKGVKVAVFEGV--NAGDKDFAAIISKLKQA-NVDFVYYGGYHPELGLILRQAKEKGLNAK-FM 250
Cdd:cd06350 173 DDYGRSGIEAFEREAKERGICIAQTIVIpeNSTEDEIKRIIDKLKSSpNAKVVVLFLTESDARELLKEAKRRNLTGFtWI 252
|
250 260
....*....|....*....|....*...
gi 1847698978 251 GPEGVGNDS-ISQIAQGASEGLLVTLPQ 277
Cdd:cd06350 253 GSDGWGDSLvILEGYEDVLGGAIGVVPR 280
|
|
| PBP1_SBP-like |
cd06327 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
31-335 |
5.69e-13 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380550 [Multi-domain] Cd Length: 336 Bit Score: 69.14 E-value: 5.69e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPvtqYGDM----QVAGAEMAVEQinAKGGVNGKMLEAKVYDDACDPKQAVAVANKIV-NDGVKFVVGHLC 105
Cdd:cd06327 1 RIGVLTDLSGV---YADLsgpgSVEAAKMAVED--FGGKVLGRPIEVVSADHQNKPDVASAIAREWYdRDGVDAIVDVPN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 106 SSSTQPASDIYEDEGIIMITPAATAPEIT-----ARGYKLVFRTigldSAQGPAAGNYIADHVKpKTVAVLHDKQQYGEG 180
Cdd:cd06327 76 SAVALAVQKLAKEKKKIAIVTGAGSSDLTgkacsPYGVHWAYDT----YALARGTVKALVKQGG-KSWFFITADYAFGHS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 181 IATAVKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAK--FMGPEGVGND 258
Cdd:cd06327 151 LEADATAAVKAAGGKVVGSVRHPLGTTDFSSFLLQAQASGADVIALANAGADLVNAVKQAREFGLTDGgqKLAALLLFIT 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1847698978 259 SISQIAQGASEGLLVTLPQAFDQLPENKALADAFQAKKQDPTGPFVFPAYSAVEVIAKAIEQTKSEDTDKVAKAIHE 335
Cdd:cd06327 231 DIHALGLDAAQGLYLTTAFYWDRDDATRAWAKRFFARTGKMPTMLQAGVYSAVLHYLKAVKAAGTDDADAVVAKMRE 307
|
|
| PBP1_YraM_LppC_lipoprotein-like |
cd06339 |
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup ... |
31-239 |
1.33e-12 |
|
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup includes periplasmic binding component of lipoprotein LppC, an immunodominant antigen, whose molecular function is not characterized. Members of this subgroup are predicted to be involved in transport of lipid compounds, and they are sequence similar to the family of ABC-type hydrophobic amino acid transporters (HAAT).
Pssm-ID: 380562 [Multi-domain] Cd Length: 331 Bit Score: 68.07 E-value: 1.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGgvngkmLEAKVYDDAcDPKQAVAVANKIVNDGVKFVVGHLCSSSTQ 110
Cdd:cd06339 1 RIALLLPLSGPYAAAGQAIRDGIELALFDAGGSR------PELRVYDTG-GPEGAAAAYQQAVAEGADLIIGPLLKSSVA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 111 PASDIYEDEGIIMITPAATAPEITARGyklVFRtIGLDS-AQGPAAGNYIADHVKpKTVAVLHDKQQYGEGIATAVKKTL 189
Cdd:cd06339 74 ALAAAAQALGVPVLALNNDESATAGPG---LFQ-FGLSPeDEARQAARYAVQQGL-RRFAVLAPDNAYGQRVANAFREAW 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1847698978 190 EDKGVKVAVFEGVNAGDKDFAAIISKLKQAN----------------------VDFVYYGGYHPELGLILRQ 239
Cdd:cd06339 149 QALGGTVVAVESYDPDETDFSAAIRRLLGVDqsearirqlgellefeprrrqdFDAIFLPAGPEQARLIAPQ 220
|
|
| PBP1_GABAb_receptor |
cd06366 |
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for ... |
51-352 |
1.33e-11 |
|
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA); Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380589 [Multi-domain] Cd Length: 404 Bit Score: 65.34 E-value: 1.33e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 51 AGAEMAVEQINAKGGV-NGKMLEAKVYDDACDPKQAVAVANKIVNDGVKFVV--GHLCSSSTQP---ASDIYEdegIIMI 124
Cdd:cd06366 22 PAAEMALEHINNRSDIlPGYNLELIWNDTQCDPGLGLKALYDLLYTPPPKVMllGPGCSSVTEPvaeASKYWN---LVQL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 125 TPAATAPEITARG-YKLVFRTIGLDSAQGPAagnYIA--DHVKPKTVAVLHDKQQYGEGIATAVKKTLEDKGVKVAVFEG 201
Cdd:cd06366 99 SYAATSPALSDRKrYPYFFRTVPSDTAFNPA---RIAllKHFGWKRVATIYQNDEVFSSTAEDLEELLEEANITIVATES 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 202 VNAGDKDFAaiISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAK-----FMG---------PEGVGNDSISQIAQgA 267
Cdd:cd06366 176 FSSEDPTDQ--LENLKEKDARIIIGLFYEDAARKVFCEAYKLGMYGPkyvwiLPGwyddnwwdvPDNDVNCTPEQMLE-A 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 268 SEGLLVTLPQAFDQLPENKA---LADAFQA------KKQDPTG-PFVFPAYSAVEVIAKAIEQT---------------- 321
Cdd:cd06366 253 LEGHFSTELLPLNPDNTKTIsglTAQEFLKeylerlSNSNYTGsPYAPFAYDAVWAIALALNKTieklaeynktledfty 332
|
330 340 350
....*....|....*....|....*....|..
gi 1847698978 322 -KSEDTDKVAKAIHEGTFKTPMGDLSFDEKGD 352
Cdd:cd06366 333 nDKEMADLFLEAMNSTSFEGVSGPVSFDSKGD 364
|
|
| PBP1_ABC_ligand_binding-like |
cd06337 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
31-348 |
2.41e-08 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380560 [Multi-domain] Cd Length: 354 Bit Score: 55.00 E-value: 2.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDmqvaGAEMAVEQIN---AKGG--VNGKM--LEAKVYDDACDPKQAVAVANKIV-NDGVKFVVG 102
Cdd:cd06337 1 KIGRVSPLTGPLAAFGE----ADPWVLEQIReafADGGikVGGKKypVEIVVRDSQSDPNRAGEAARDLIlRDKVDLMLA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 103 HLCSSSTQPASDIYEDEGIIMITPAAT-APEITARGYKLVFRT-------IGLDSAqgpaAGNYIA--DHVK-PKTVAVL 171
Cdd:cd06337 77 SGTPDTVNPVADQCEANGVPCISTDAPwQAWFFGRGGDPAKGFkwtfhffWGLEDI----AANFLGmwDQVPtNKVVGLL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 172 HDKQQYGEGIATAVKKTLEDKGVKVAVFEGVNAGDKDFAAIISKLKQANVDFVYYGGYHPELGLILRQAKEKGLNAK--- 248
Cdd:cd06337 153 WPNDPDGTAFADAFLGLPAAAGYTLVDPGRFPPGTDDFSSIINAFKKAGVEIVTGVMIPPDFATFWRQAAQQGFKPKvvt 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 249 ------FMGPEGVGNDsisqiaqgASEGLLVTL---PqafdQLP--------ENKALADAF-QAKKQDPTGPFVFpAYSA 310
Cdd:cd06337 233 igkallFPSAVAALGD--------LGDGLSTEVwwsP----AHPfkssltgqTAAELADAYeKATGKQWTQPLGY-AHAL 299
|
330 340 350
....*....|....*....|....*....|....*...
gi 1847698978 311 VEVIAKAIEQTKSEDTDKVAKAIHEGTFKTPMGDLSFD 348
Cdd:cd06337 300 FEVAVDALKRAGSPDDEAVRAALADTDLDTIVGPVDFT 337
|
|
| PBP1_glutamate_receptors-like |
cd06269 |
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl ... |
44-217 |
3.68e-08 |
|
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as natriuretic peptide receptors (NPRs), and N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of ionotropic glutamate rece; This CD represents the ligand-binding domain of the family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs), and the N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the ionotropic glutamate receptors, all of which are structurally similar and related to the periplasmic-binding fold type 1 family. The family C GPCRs consists of metabotropic glutamate receptor (mGluR), a calcium-sensing receptor (CaSR), gamma-aminobutyric acid receptor (GABAbR), the promiscuous L-alpha-amino acid receptor GPR6A, families of taste and pheromone receptors, and orphan receptors. Truncated splicing variants of the orphan receptors are not included in this CD. The family C GPCRs are activated by endogenous agonists such as amino acids, ions, and sugar based molecules. Their amino terminal ligand-binding region is homologous to the bacterial leucine-isoleucine-valine binding protein (LIVBP) and a leucine binding protein (LBP). The ionotropic glutamate receptors (iGluRs) have an integral ion channel and are subdivided into three major groups based on their pharmacology and structural similarities: NMDA receptors, AMPA receptors, and kainate receptors. The family of membrane bound guanylyl cyclases is further divided into three subfamilies: the ANP receptor (GC-A)/C-type natriuretic peptide receptor (GC-B), the heat-stable enterotoxin receptor (GC-C)/sensory organ specific membrane GCs such as retinal receptors (GC-E, GC-F), and olfactory receptors (GC-D and GC-G).
Pssm-ID: 380493 [Multi-domain] Cd Length: 332 Bit Score: 54.35 E-value: 3.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 44 QYGDMQVAGAEMAVEQINAKG-GVNGKMLEAKVYDDACDPKQAVAVA-NKIVNDGVKFVVGHLCSSSTQPASDIYEDEGI 121
Cdd:cd06269 13 ESGAKVLPAFELALSDVNSRPdLLPKTTLGLAIRDSECNPTQALLSAcDLLAAAKVVAILGPGCSASAAPVANLARHWDI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 122 IMITPAATAPEITAR-GYKLVFRTIGLDSAQGPAAGNyIADHVKPKTVAVLHDKQQYGEGIATAVKKTLEDKGVKVA--- 197
Cdd:cd06269 93 PVLSYGATAPGLSDKsRYAYFLRTVPPDSKQADAMLA-LVRRLGWNKVVLIYSDDEYGEFGLEGLEELFQEKGGLITsrq 171
|
170 180
....*....|....*....|.
gi 1847698978 198 -VFEGVnagDKDFAAIISKLK 217
Cdd:cd06269 172 sFDENK---DDDLTKLLRNLR 189
|
|
| PBP1_NHase |
cd06358 |
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively ... |
31-225 |
3.54e-07 |
|
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides; This group includes the type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides, which are subsequently converted by amidases to yield free carboxylic acids and ammonia. NHases from bacteria and fungi have been purified and characterized. In Rhodococcus sp., the nitrile hydratase operon consists of six genes encoding NHase regulator 2, NHase regulator 1, amidase, NHase alpha subunit, NHase beta subunit, and NHase activator. The operon produces a constitutive hydratase that has a broad substrate spectrum: aliphatic and aromatic nitriles, mononitriles and dinitriles, hydroxynitriles and amino-nitriles, and a constitutive amidase of equally low substrate specificity. NHases are metalloenzymes containing either cobalt or iron, and therefore can be classified into two subgroups: ferric NHases and cobalt NHases.
Pssm-ID: 380581 [Multi-domain] Cd Length: 333 Bit Score: 51.44 E-value: 3.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 31 KIGIAGARTGPVTQYGDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVANKIVNDG-VKFVVG-HLcSSS 108
Cdd:cd06358 1 RIGLLIPLSGPAGLWGPSCEACAELAAAEINAAGGILGREVELVLIDAGGPPAEVAAAARRLVDDGaVDAIVGmHT-SAV 79
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 109 TQPASDI------------YE----DEGIIMI--TPaatapeitargyklvfrtigldSAQGPAAGNYIADHVKPKTVAV 170
Cdd:cd06358 80 RQALANAvggrvpyvytplYEggerTPGVYAIgeTP----------------------EEQLRPALRWLADERRVRRWFL 137
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170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1847698978 171 LHDKQQYGEGIATAVKKTLEDKGVKVaVFEG-VNAGDKDFAAIISKLKQANVDFVY 225
Cdd:cd06358 138 VGNDYVWPRASHAAARRYIARLGGEV-VGERfVPLGEDDFERVLARIRASRPDAVL 192
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| PBP1_mGluR |
cd06362 |
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of ... |
97-363 |
7.04e-07 |
|
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of the metabotropic glutamate receptors (mGluR), which are members of the family C of G-protein-coupled receptors that transduce extracellular signals into G-protein activation and ultimately into cellular responses. mGluRs bind to glutamate and function as an excitatory neurotransmitter; they are involved in learning, memory, anxiety, and the perception of pain. Eight subtypes of mGluRs have been cloned so far, and are classified into three groups according to their sequence similarities, transduction mechanisms, and pharmacological profiles. Group I is composed of mGlu1R and mGlu5R that both stimulate PLC hydrolysis. Group II includes mGlu2R and mGlu3R, which inhibit adenylyl cyclase, as do mGlu4R, mGlu6R, mGlu7R, and mGlu8R, which form group III.
Pssm-ID: 380585 [Multi-domain] Cd Length: 460 Bit Score: 50.75 E-value: 7.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 97 VKFVVGHLCSSSTQPASDIYEDEGIIMITPAATAPEI-TARGYKLVFRTIGLDSAQGPAagnyIAD---HVKPKTVAVLH 172
Cdd:cd06362 108 VVGVIGAESSSVSIQVANLLRLFKIPQISYASTSDELsDKERYPYFLRTVPSDSFQAKA----IVDillHFNWTYVSVVY 183
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 173 DKQQYGEGIATAVKKTLEDKGVKVAVFEGV--NAGDKDFAAIISKLKQ---ANVDFVYYGGyhPELGLILRQAKEKGLNA 247
Cdd:cd06362 184 SEGSYGEEGYKAFKKLARKAGICIAESERIsqDSDEKDYDDVIQKLLQkknARVVVLFADQ--EDIRGLLRAAKRLGASG 261
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170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 248 KFM--GPEGVGNDS-----ISQIAQGAsegLLVTLPQA--------FDQL-----PENKALADAFQAKKQ---DPTGP-- 302
Cdd:cd06362 262 RFIwlGSDGWGTNIddlkgNEDVALGA---LTVQPYSEevprfddyFKSLtpsnnTRNPWFREFWQELFQcsfRPSREns 338
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250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 303 ------------------FVFPAYSAVEVIAKAIE----------------QTKSEDTDKVAKAIHEGTFKTPMGD-LSF 347
Cdd:cd06362 339 cnddkllinksegykqesKVSFVIDAVYAFAHALHkmhkdlcpgdtglcqdLMKCIDGSELLEYLLNVSFTGEAGGeIRF 418
|
330 340
....*....|....*....|....*
gi 1847698978 348 DEKGD------LKNFKFVI---YEW 363
Cdd:cd06362 419 DENGDgpgrydIMNFQRNNdgsYEY 443
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|
| PBP1_GABAb_receptor_plant |
cd19990 |
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close ... |
46-360 |
2.16e-06 |
|
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants; This group includes the ligand-binding domain of Arabidopsis thaliana glutamate receptors, which have sequence similarity with animal ionotropic glutamate receptor and its close homologs in other plants. The ligand-binding domain of GABAb receptors are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380645 [Multi-domain] Cd Length: 373 Bit Score: 49.15 E-value: 2.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 46 GDMQVAGAEMAVEQINAKGGVNGKMLEAKVYDDACDPKQAVAVA-NKIVNDGVKFVVGHLCSSSTQPASDIYEDEGIIMI 124
Cdd:cd19990 13 GKEAKVAIEMAVSDFNSDSSSYGTKLVLHVRDSKGDPLQAASAAlDLIKNKKVEAIIGPQTSEEASFVAELGNKAQVPII 92
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 125 TPAATAPEITARGYKLVFRTIGLDSAQGPAagnyIADHVKP---KTVAVLHDKQQYGEGIATAVKKTLEDKGVKV---AV 198
Cdd:cd19990 93 SFSATSPTLSSLRWPFFIRMTHNDSSQMKA----IAAIVQSygwRRVVLIYEDDDYGSGIIPYLSDALQEVGSRIeyrVA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 199 FEgVNAGDKDFAAIISKLK--QANVdFVYYGGyhPELGLIL-RQAKEKGLnakfMG-------PEGVGN--DSISQIAQG 266
Cdd:cd19990 169 LP-PSSPEDSIEEELIKLKsmQSRV-FVVHMS--SLLASRLfQEAKKLGM----MEkgyvwivTDGITNllDSLDSSTIS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847698978 267 ASEGLLVTLPQaFDQLPENKALADAFQAK---------KQDPtGPFVFPAYSAVEVIAKAIE--------QTKSEDTDKV 329
Cdd:cd19990 241 SMQGVIGIKTY-IPESSEFQDFKARFRKKfrseypeeeNAEP-NIYALRAYDAIWALAHAVEklnssggnISVSDSGKKL 318
|
330 340 350
....*....|....*....|....*....|.
gi 1847698978 330 AKAIHEGTFKTPMGDLSFDEKGDLKNFKFVI 360
Cdd:cd19990 319 LEEILSTKFKGLSGEVQFVDGQLAPPPAFEI 349
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