|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
10-998 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1091.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 10 IRARMLVLGGLGLLLAAGIMTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGG 89
Cdd:COG3696 10 LRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSISRFG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 90 VSVVYVQFADDTDINLDRTRVNERMQQARSNISvPGITVSMGPLATGMGEIMQFQIRGAG--RSLMELNRIMNWTVVPQM 167
Cdd:COG3696 90 LSVVTVIFEDGTDIYWARQLVLERLQQVREQLP-AGVTPELGPISTGLGEIYQYTLESDPgkYSLMELRTLQDWVIRPQL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 168 RLVPGVVDVNVNGGAEETYEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLADFGNIAV 247
Cdd:COG3696 169 RSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSLEDIENIVV 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 248 RTNpDGSAVRLRDLGRITRGARTRLGAVTRDGQGEIVIGVVMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRA 327
Cdd:COG3696 249 KTR-NGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVKIVPFYDRS 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 328 TLTGQTIATVRDNLVMGAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLG--AIDFGMIVDGSL 405
Cdd:COG3696 328 DLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGglAIDFGIIVDGAV 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 406 VVIEHVLSRREEEPDA----EFIPLVISSVQQVMRPVGFAILVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYC 481
Cdd:COG3696 408 VMVENILRRLEENRAAgtprERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFALLGALLLS 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 482 FICVPVLAALALGGVRPAGDTRLIAFLRRPYTHMVTWGETHPRILFGGTLVVLALSAGLAMRLGGEFIPQLDEGALAVTT 561
Cdd:COG3696 488 LTLVPVLASLLLRGKVPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMA 567
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 562 TRLPSASLDTVLASVTKQEQILRSFPEVRAVVSNTGTSAIPTDPMGVNETDSFIFLNPPSTWKTARTQAGLVAAMDDTLR 641
Cdd:COG3696 568 TLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGRTKEELIAEMREALE 647
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 642 rELPDALYSWSQPVQMRMDDLLSGVRTQIAVSIFGDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGTVPLIVVDIDRTQ 721
Cdd:COG3696 648 -QIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDIRIDRDA 726
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 722 AASRNVAVQDILDTVE-AIGGHIgARPVIVDNAIIGTQVRLDPRVATSAAAIGALQVRRMDGQgNAMLSQVAHVHEVDGP 800
Cdd:COG3696 727 AARYGLNVADVQDVVEtAIGGKA-VGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGA-QVPLSQVADIEVVEGP 804
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 801 PRISRDRVRRRMVVQANVRGRDLASFVAEAQARVARDVKLPAGYNMQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVA 880
Cdd:COG3696 805 NQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFLLLYLA 884
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 881 FGAVRPALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVSEIAALRARGMAVAQAAFAAAESRF 960
Cdd:COG3696 885 FGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGALERL 964
|
970 980 990
....*....|....*....|....*....|....*...
gi 1846948815 961 RPVMATALVASLGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:COG3696 965 RPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGG 1002
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
10-998 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 739.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 10 IRARMLVLGGLGLLLAAGIMTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGG 89
Cdd:TIGR00914 10 VAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSRYG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 90 VSVVYVQFADDTDINLDRTRVNERMQQARSNISvPGITVSMGPLATGMGEIMQFQI---------RGAGRSLMELNRIMN 160
Cdd:TIGR00914 90 LSQVTVIFKDGTDLYFARQLVNERLQQARDNLP-EGVSPEMGPISTGLGEIFLYTVeaeegarkkDGGAYTLTDLRTIQD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 161 WTVVPQMRLVPGVVDVNVNGGAEETYEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLA 240
Cdd:TIGR00914 169 WIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRAPGQVQSMD 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 241 DFGNIAVRTNpDGSAVRLRDLGRITRGARTRLGAVTRDGQgEIVIGVVMMESGASSNATLAAINRALPGIRQALPAGVTI 320
Cdd:TIGR00914 249 DIRNIVIATG-EGVPIRIRDVARVQIGKELRTGAATENGK-EVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPEGVEI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 321 EPYYTRATLTGQTIATVRDNLVMGAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGAIDFGMI 400
Cdd:TIGR00914 327 VTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGALDFGLI 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 401 VDGSLVVIEHVLSRREEEPDAEFIPL--------VISSVQQVMRPVGFAILVIIMVYLPILTLQGIEGHMFRPMAQTVIM 472
Cdd:TIGR00914 407 VDGAVVIVENAHRRLAEAQHHHGRQLtlkerlheVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPMAFTVVL 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 473 ALLASLAYCFICVPVLAALALGGVRPAGDTRLIAFLRRPYTHMVTWGETHPRILFGGTLVVLALSAGLAMRLGGEFIPQL 552
Cdd:TIGR00914 487 ALAGAMILSLTFVPAAVALFIRGKVAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASRVGGEFIPSL 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 553 DEGALAVTTTRLPSASLDTVLASVTKQEQILRSFPEVRAVVSNTGTSAIPTDPMGVNETDSFIFLNPPSTWKT-ARTQAG 631
Cdd:TIGR00914 567 NEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPESQWPEgKKTKED 646
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 632 LVAAMDDTLRReLPDALYSWSQPVQMRMDDLLSGVRTQIAVSIFGDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGTVP 711
Cdd:TIGR00914 647 LIEEIQEATVR-IPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAADVKVEQTTGLP 725
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 712 LIVVDIDRTQAASRNVAVQDILDTVE-AIGGHIGARPVIVDnAIIGTQVRLDPRVATSAAAIGALQVRRMDGQGNAM--- 787
Cdd:TIGR00914 726 YLTVEIDREKAARYGLTVGDVQDTVAtAVGGRMSGETFEGD-RRFDIVIRLPESLRESPQALRQLPIPLPLSEDARKqfi 804
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 788 -LSQVAHVHEVDGPPRISRDRVRRRMVVQANVRGRDLASFVAEAQARVARDVKLPAGYNMQWDGQFRNLQSATRRLEIVL 866
Cdd:TIGR00914 805 pLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQSATKRLQIVV 884
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 867 PVALGLIFALLVVAFGAVRPALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVSEIAALRARGM 946
Cdd:TIGR00914 885 PVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGP 964
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|..
gi 1846948815 947 AVAQAAFAAAESRFRPVMATALVASLGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:TIGR00914 965 SLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGG 1016
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
28-998 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 635.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 28 IMTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGGVSVVYVQFADDTDINLDR 107
Cdd:pfam00873 24 ILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSSQSSYGLSSITLTFELGTDIDIAR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 108 TRVNERMQQARSNISVPGITVSMGPLATGMGEIMQFQIRGAGRSL--MELNRIMNWTVVPQMRLVPGVVDVNVNGGAEET 185
Cdd:pfam00873 104 QDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYtqTDLRDYADTNIKPQLSRVPGVGDVQLFGGSEYA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 186 YEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLADFGNIAVRtNPDGSAVRLRDLGRIT 265
Cdd:pfam00873 184 MRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDFEKIIVK-NQDGSPVRLRDVATVE 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 266 RGARTRLGAVTRDGQgEIVIGVVMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQTIATVRDNLVMGA 345
Cdd:pfam00873 263 LGSELYRGFATFNGK-PAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVVYDTTPFIRASIEEVVKTLLEAI 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 346 VLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGAIDF--GMIVDGSLVVIEHVlSRREEEPDAEF 423
Cdd:pfam00873 342 VLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLaiGLVVDDAIVVVENI-ERVLEENGLKP 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 424 IPLVISSVQQVMRPVGFAILVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPVLAALALGGVRPAGD-- 501
Cdd:pfam00873 421 LEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVALTLTPALCATLLKPRREPKHgg 500
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 502 -----TRLIAFLRRPYTHMVTWGETHPRILFGGTLVVLALSAGLAMRLGGEFIPQLDEGALAVTTTRLPSASLDTVLASV 576
Cdd:pfam00873 501 ffrwfNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVM 580
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 577 TKQEQILRSFPEVRAVVSNTGTsAIPTDPMGVNETDSFIFLNPPSTWKTA-RTQAGLVAAMDDTLRrELPDALYSWSQPV 655
Cdd:pfam00873 581 KQVEKILKEKPEVESVFAVTGF-AFSGDNNGPNSGDAFISLKPWKERPGPeKSVQALIERLRKALK-QIPGANVFLFQPI 658
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 656 QMRMDDLLSGVRTQIAVSIFGDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGTVPLIVVDIDRTQAASRNVAVQDILDT 735
Cdd:pfam00873 659 QLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDT 738
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 736 VE-AIGGHIgARPVIVDNAIIGTQVRLDPRVATSAAAIGALQVRRMDGQgnaM--LSQVAHVHEVDGPPRISRDRVRRRM 812
Cdd:pfam00873 739 LStALGGSY-VNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGK---MipLSAFAKIEWGYGPPSINRYNGFRSI 814
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 813 VVQANVRGRDLASFVAEAQARVARDVKLPAGYNMQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVAFGAVRPALLVFV 892
Cdd:pfam00873 815 VISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALLVVFLVLAALYESWSDPLSIML 894
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 893 NLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVSEIAALRAR-GMAVAQAAFAAAESRFRPVMATALVAS 971
Cdd:pfam00873 895 TVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQeGKSLEEAILEACRLRLRPILMTALAAI 974
|
970 980
....*....|....*....|....*..
gi 1846948815 972 LGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:pfam00873 975 LGVLPLALSTGAGSELQQPLGIVVFGG 1001
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
34-1007 |
9.08e-86 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 298.47 E-value: 9.08e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 34 LPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGGVSVVYVQFADDTDINLDRTRVNER 113
Cdd:NF033617 29 LPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQFRLGTDLDVALSEVQAA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 114 MQQARSNISV----PGITVSMGPLATGmgeIMQFQIRGAGRSLMELNRIMNWTVVPQMRLVPGVVDVNVNGGAEETYEVT 189
Cdd:NF033617 109 INAAQSLLPSeapdPPVYRKANSADTP---IMYIGLTSEEMPRGQLTDYAERVLAPKLSQINGVGSVDVSGGQRPAMRVW 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 190 LDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLADFGNIAVRTNPDGSAVRLRDLGRITRGAR 269
Cdd:NF033617 186 LDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYADNGAPVRLGDVATVELGAE 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 270 TRLGAVTRDGQGEIVIGVVMmESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQTIATVRDNLVMGAVLVV 349
Cdd:NF033617 266 NVRNRAWANGVPAVVLGINR-QPGANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFIRASIDEVESTLLEAVALVI 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 350 GVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGA--IDFGMIVDGSLVVIEHVlSRREEEPDAEFIPLV 427
Cdd:NF033617 345 LVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMAlvLAIGLVVDDAIVVVENI-HRHIEEGESPLEAAL 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 428 ISSvqqvmRPVGFAI----LVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPVLAALAL------GGVR 497
Cdd:NF033617 424 KGA-----REIGFTViamtLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPMMCSRLLkanekpGRFA 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 498 PAGDtRLIAFLRRPYTHMVTWGETHPRILFGGTLVVLALSAGLAMRLGGEFIPQLDEGALAVTTTRLPSASLDTVLASVT 577
Cdd:NF033617 499 RAVD-RFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMR 577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 578 KQEQILRSFPEVRAVVSNTGTSAIPTDPMGvnetdsFIFLNPPSTWKTARTQAGLVAAMDDTLRRELPDALYSWSqpvqm 657
Cdd:NF033617 578 DVEKILSSDPEVQSLTSFNGVGGNPGDNTG------FGIINLKPWDERDVSAQEIIDRLRPKLAKVPGMDLFLFP----- 646
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 658 rMDDLLSGV---RTQIAVSIFGDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGTVPLIVVDIDRTQAASRNVAVQDILD 734
Cdd:NF033617 647 -LQDLPGGAgssLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGS 725
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 735 TVE-AIGGHIGARpvivdnaiIGTQVR-------LDPRVATSAAAIGALQVRRMDGQGNAmLSQVAHVHEVDGPPRISRD 806
Cdd:NF033617 726 TLEvAFGQRQVNT--------IYTDGNqykvvleVDRRYRLNPEALNQIYVRSNDGKLVP-LSTLAKIEERAAPLSLNHF 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 807 RVRRRMVVQANVRGRDLASFVAEAQARVARDvKLPAGYNMQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVAFGAVRP 886
Cdd:NF033617 797 NQFNSATLSFNLAPGVSLGEAIEALDQAAKE-LLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVD 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 887 ALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVS-EIAALRARGMAVAQAAFAAAESRFRPVMA 965
Cdd:NF033617 876 PLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEfANELQRHQGLSRREAIYQAAALRLRPILM 955
|
970 980 990 1000
....*....|....*....|....*....|....*....|..
gi 1846948815 966 TALVASLGFFPMAFSESAGAEVERPLASVVIGGLVTSTLLTL 1007
Cdd:NF033617 956 TTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTL 997
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
28-998 |
3.19e-53 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 202.39 E-value: 3.19e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 28 IMTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGGVSVVYVQFADDTDINLDR 107
Cdd:PRK09577 24 IFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAGQASLSLTFKQGVNADLAA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 108 TRVNERMQQARSNISVP----GITVSMGplATGMGEIMQFQIRGAGRSLMELNRIMNWTVVPQMRLVPGVVDVNVnGGAE 183
Cdd:PRK09577 104 VEVQNRLKTVEARLPEPvrrdGIQVEKA--ADNIQLIVSLTSDDGRLTGVELGEYASANVLQALRRVEGVGKVQF-WGAE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 184 ETYEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQS------VVGRGLVGSLADFGNIAVRTNPDGSAVR 257
Cdd:PRK09577 181 YAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSapiaatVFADAPLKTPEDFGAIALRARADGSALY 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 258 LRDLGRITRGAR-----TRLGAVTRDGQGeivigvVMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQ 332
Cdd:PRK09577 261 LRDVARIEFGGNdynypSYVNGKTATGMG------IKLAPGSNAVATEKRVRATMDELSRYFPPGVKYQIPYETSSFVRV 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 333 TIATVRDNLVMGAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLgaidFGMI------VDGSLV 406
Cdd:PRK09577 335 SMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTM----FGMVlaigilVDDAIV 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 407 VIEHVLSRREEEPDAEFIPLVissvqQVMRPVGFAIL----VIIMVYLPILTLQGIEGHMFRPMAqtviMALLASLAY-C 481
Cdd:PRK09577 411 VVENVERLMVEEGLSPYDATV-----KAMKQISGAIVgitvVLTSVFVPMAFFGGAVGNIYRQFA----LSLAVSIGFsA 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 482 FICVPVLAALALGGVRPAGD------------------------TRLIAFLRRPYTHMVTWGethprilfggtlVVLALS 537
Cdd:PRK09577 482 FLALSLTPALCATLLKPVDGdhhekrgffgwfnrfvarstqryaTRVGAILKRPLRWLVVYG------------ALTAAA 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 538 AGLAMRLGGEFIPQLDEGALAVTTTRLPSASLDTVLASVTKQEQILRSFPEVRAVVSNTGTSAIPTdpmGVNETDSFIFL 617
Cdd:PRK09577 550 ALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGE---GPNGGMIFVTL 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 618 NPPSTWKTARTQAGLVAAMDDTLRRELPD-ALYSWSQPVqmrMDDLLSG----VRTQIAVSIfgdDLAMLAELGDRVVAA 692
Cdd:PRK09577 627 KDWKERKAARDHVQAIVARINERFAGTPNtTVFAMNSPA---LPDLGSTsgfdFRLQDRGGL---GYAAFVAAREQLLAE 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 693 MSGVKGAADVAAAGDGTVPLIVVDIDRTQAASRNVAVQDILDTVEAIGG--HIGarpvivdNAIIGTQVR-----LDPRV 765
Cdd:PRK09577 701 GAKDPALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGsdYIG-------DFMHGSQVRrvivqADGRH 773
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 766 ATSAAAIGALQVRRMDGQGNAmLSQVAHVHEVDGPPRISRDRVRRRMVVQANVRGRDLASFVAEAQARVARdvKLPAGYN 845
Cdd:PRK09577 774 RLDPDDVKKLRVRNAQGEMVP-LAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAA--TLPAGIG 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 846 MQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVAFGAVRPALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFG 925
Cdd:PRK09577 851 YAWSGQSFEERLSGAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIG 930
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1846948815 926 VAILNGVVLVSEIAALRARGMAVAQAAFAAAESRFRPVMATALVASLGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:PRK09577 931 LSAKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGG 1003
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
10-998 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1091.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 10 IRARMLVLGGLGLLLAAGIMTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGG 89
Cdd:COG3696 10 LRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSISRFG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 90 VSVVYVQFADDTDINLDRTRVNERMQQARSNISvPGITVSMGPLATGMGEIMQFQIRGAG--RSLMELNRIMNWTVVPQM 167
Cdd:COG3696 90 LSVVTVIFEDGTDIYWARQLVLERLQQVREQLP-AGVTPELGPISTGLGEIYQYTLESDPgkYSLMELRTLQDWVIRPQL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 168 RLVPGVVDVNVNGGAEETYEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLADFGNIAV 247
Cdd:COG3696 169 RSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSLEDIENIVV 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 248 RTNpDGSAVRLRDLGRITRGARTRLGAVTRDGQGEIVIGVVMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRA 327
Cdd:COG3696 249 KTR-NGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVKIVPFYDRS 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 328 TLTGQTIATVRDNLVMGAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLG--AIDFGMIVDGSL 405
Cdd:COG3696 328 DLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGglAIDFGIIVDGAV 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 406 VVIEHVLSRREEEPDA----EFIPLVISSVQQVMRPVGFAILVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYC 481
Cdd:COG3696 408 VMVENILRRLEENRAAgtprERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFALLGALLLS 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 482 FICVPVLAALALGGVRPAGDTRLIAFLRRPYTHMVTWGETHPRILFGGTLVVLALSAGLAMRLGGEFIPQLDEGALAVTT 561
Cdd:COG3696 488 LTLVPVLASLLLRGKVPEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMA 567
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 562 TRLPSASLDTVLASVTKQEQILRSFPEVRAVVSNTGTSAIPTDPMGVNETDSFIFLNPPSTWKTARTQAGLVAAMDDTLR 641
Cdd:COG3696 568 TLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGRTKEELIAEMREALE 647
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 642 rELPDALYSWSQPVQMRMDDLLSGVRTQIAVSIFGDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGTVPLIVVDIDRTQ 721
Cdd:COG3696 648 -QIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDIRIDRDA 726
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 722 AASRNVAVQDILDTVE-AIGGHIgARPVIVDNAIIGTQVRLDPRVATSAAAIGALQVRRMDGQgNAMLSQVAHVHEVDGP 800
Cdd:COG3696 727 AARYGLNVADVQDVVEtAIGGKA-VGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGA-QVPLSQVADIEVVEGP 804
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 801 PRISRDRVRRRMVVQANVRGRDLASFVAEAQARVARDVKLPAGYNMQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVA 880
Cdd:COG3696 805 NQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFLLLYLA 884
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 881 FGAVRPALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVSEIAALRARGMAVAQAAFAAAESRF 960
Cdd:COG3696 885 FGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGALERL 964
|
970 980 990
....*....|....*....|....*....|....*...
gi 1846948815 961 RPVMATALVASLGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:COG3696 965 RPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGG 1002
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
10-998 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 739.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 10 IRARMLVLGGLGLLLAAGIMTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGG 89
Cdd:TIGR00914 10 VAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSRYG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 90 VSVVYVQFADDTDINLDRTRVNERMQQARSNISvPGITVSMGPLATGMGEIMQFQI---------RGAGRSLMELNRIMN 160
Cdd:TIGR00914 90 LSQVTVIFKDGTDLYFARQLVNERLQQARDNLP-EGVSPEMGPISTGLGEIFLYTVeaeegarkkDGGAYTLTDLRTIQD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 161 WTVVPQMRLVPGVVDVNVNGGAEETYEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLA 240
Cdd:TIGR00914 169 WIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRAPGQVQSMD 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 241 DFGNIAVRTNpDGSAVRLRDLGRITRGARTRLGAVTRDGQgEIVIGVVMMESGASSNATLAAINRALPGIRQALPAGVTI 320
Cdd:TIGR00914 249 DIRNIVIATG-EGVPIRIRDVARVQIGKELRTGAATENGK-EVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPEGVEI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 321 EPYYTRATLTGQTIATVRDNLVMGAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGAIDFGMI 400
Cdd:TIGR00914 327 VTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGALDFGLI 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 401 VDGSLVVIEHVLSRREEEPDAEFIPL--------VISSVQQVMRPVGFAILVIIMVYLPILTLQGIEGHMFRPMAQTVIM 472
Cdd:TIGR00914 407 VDGAVVIVENAHRRLAEAQHHHGRQLtlkerlheVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPMAFTVVL 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 473 ALLASLAYCFICVPVLAALALGGVRPAGDTRLIAFLRRPYTHMVTWGETHPRILFGGTLVVLALSAGLAMRLGGEFIPQL 552
Cdd:TIGR00914 487 ALAGAMILSLTFVPAAVALFIRGKVAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASRVGGEFIPSL 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 553 DEGALAVTTTRLPSASLDTVLASVTKQEQILRSFPEVRAVVSNTGTSAIPTDPMGVNETDSFIFLNPPSTWKT-ARTQAG 631
Cdd:TIGR00914 567 NEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPESQWPEgKKTKED 646
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 632 LVAAMDDTLRReLPDALYSWSQPVQMRMDDLLSGVRTQIAVSIFGDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGTVP 711
Cdd:TIGR00914 647 LIEEIQEATVR-IPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAADVKVEQTTGLP 725
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 712 LIVVDIDRTQAASRNVAVQDILDTVE-AIGGHIGARPVIVDnAIIGTQVRLDPRVATSAAAIGALQVRRMDGQGNAM--- 787
Cdd:TIGR00914 726 YLTVEIDREKAARYGLTVGDVQDTVAtAVGGRMSGETFEGD-RRFDIVIRLPESLRESPQALRQLPIPLPLSEDARKqfi 804
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 788 -LSQVAHVHEVDGPPRISRDRVRRRMVVQANVRGRDLASFVAEAQARVARDVKLPAGYNMQWDGQFRNLQSATRRLEIVL 866
Cdd:TIGR00914 805 pLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQSATKRLQIVV 884
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 867 PVALGLIFALLVVAFGAVRPALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVSEIAALRARGM 946
Cdd:TIGR00914 885 PVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGP 964
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|..
gi 1846948815 947 AVAQAAFAAAESRFRPVMATALVASLGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:TIGR00914 965 SLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGG 1016
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
28-998 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 635.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 28 IMTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGGVSVVYVQFADDTDINLDR 107
Cdd:pfam00873 24 ILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSSQSSYGLSSITLTFELGTDIDIAR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 108 TRVNERMQQARSNISVPGITVSMGPLATGMGEIMQFQIRGAGRSL--MELNRIMNWTVVPQMRLVPGVVDVNVNGGAEET 185
Cdd:pfam00873 104 QDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYtqTDLRDYADTNIKPQLSRVPGVGDVQLFGGSEYA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 186 YEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLADFGNIAVRtNPDGSAVRLRDLGRIT 265
Cdd:pfam00873 184 MRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDFEKIIVK-NQDGSPVRLRDVATVE 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 266 RGARTRLGAVTRDGQgEIVIGVVMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQTIATVRDNLVMGA 345
Cdd:pfam00873 263 LGSELYRGFATFNGK-PAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVVYDTTPFIRASIEEVVKTLLEAI 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 346 VLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGAIDF--GMIVDGSLVVIEHVlSRREEEPDAEF 423
Cdd:pfam00873 342 VLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLaiGLVVDDAIVVVENI-ERVLEENGLKP 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 424 IPLVISSVQQVMRPVGFAILVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPVLAALALGGVRPAGD-- 501
Cdd:pfam00873 421 LEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVALTLTPALCATLLKPRREPKHgg 500
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 502 -----TRLIAFLRRPYTHMVTWGETHPRILFGGTLVVLALSAGLAMRLGGEFIPQLDEGALAVTTTRLPSASLDTVLASV 576
Cdd:pfam00873 501 ffrwfNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVM 580
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 577 TKQEQILRSFPEVRAVVSNTGTsAIPTDPMGVNETDSFIFLNPPSTWKTA-RTQAGLVAAMDDTLRrELPDALYSWSQPV 655
Cdd:pfam00873 581 KQVEKILKEKPEVESVFAVTGF-AFSGDNNGPNSGDAFISLKPWKERPGPeKSVQALIERLRKALK-QIPGANVFLFQPI 658
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 656 QMRMDDLLSGVRTQIAVSIFGDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGTVPLIVVDIDRTQAASRNVAVQDILDT 735
Cdd:pfam00873 659 QLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDT 738
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 736 VE-AIGGHIgARPVIVDNAIIGTQVRLDPRVATSAAAIGALQVRRMDGQgnaM--LSQVAHVHEVDGPPRISRDRVRRRM 812
Cdd:pfam00873 739 LStALGGSY-VNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGK---MipLSAFAKIEWGYGPPSINRYNGFRSI 814
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 813 VVQANVRGRDLASFVAEAQARVARDVKLPAGYNMQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVAFGAVRPALLVFV 892
Cdd:pfam00873 815 VISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALLVVFLVLAALYESWSDPLSIML 894
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 893 NLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVSEIAALRAR-GMAVAQAAFAAAESRFRPVMATALVAS 971
Cdd:pfam00873 895 TVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQeGKSLEEAILEACRLRLRPILMTALAAI 974
|
970 980
....*....|....*....|....*..
gi 1846948815 972 LGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:pfam00873 975 LGVLPLALSTGAGSELQQPLGIVVFGG 1001
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
28-1002 |
1.66e-172 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 531.22 E-value: 1.66e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 28 IMTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGGVSVVYVQFADDTDINLDR 107
Cdd:COG0841 26 LLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITSTSSEGSSSITVEFELGTDIDEAL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 108 TRVNERMQQARSN----ISVPGITVSmgplATGMGEIMQFQIRGAGRSLMELNRIMNWTVVPQMRLVPGVVDVNVNGGAE 183
Cdd:COG0841 106 VDVQNAVDRARSDlpedVEPPGVTKV----NPSDFPVMVLALSSDDLDELELSDYAERNIKDRLERVPGVGQVQIFGGRE 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 184 ETYEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLADFGNIAVRTNpDGSAVRLRDLGR 263
Cdd:COG0841 182 REIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEEFENIVIRTN-DGSVVRLGDVAR 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 264 ITRGARTRLGAVTRDGQGEIVIGVvMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQTIATVRDNLVM 343
Cdd:COG0841 261 VEDGAEDYRSIARLNGKPAVGLAI-QKQPGANALEVADAVRAKLEELQASLPEGVELTIVYDQSEFIRASIEEVVKTLLE 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 344 GAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGAIDF--GMIVDGSLVVIEHVLSRREEEPDA 421
Cdd:COG0841 340 AILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLaiGIVVDDAIVVVENIERHMEEGLSP 419
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 422 efIPLVISSVQQVMRPVGFAILVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPVLAALALGGVRPAGD 501
Cdd:COG0841 420 --LEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALTLTPALCARLLKPHPKGKK 497
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 502 TRLIAF-------LRRPYTHMVTWGETHPRILFGGTLVVLALSAGLAMRLGGEFIPQLDEGALAVTTTRLPSASLDTVLA 574
Cdd:COG0841 498 GRFFRAfnrgfdrLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEA 577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 575 SVTKQEQILRSFPEVRAVVSNTGTSAIPTdpmGVNETDSFIFLNPPSTWKtaRTQAGLVAAMDDTLRrELPDALYSWSQP 654
Cdd:COG0841 578 VVRQVEEILLEVPEVESVFSVVGFSGGGS---GSNSGTIFVTLKPWDERD--RSADEIIARLREKLA-KIPGARVFVFQP 651
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 655 vqmrmDDLLSGVRTQIAVSIFGDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGTVPLIVVDIDRTQAASRNVAVQDILD 734
Cdd:COG0841 652 -----PAGGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAAALGVTVADVAS 726
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 735 TVE-AIGGHIGARpVIVDNAIIGTQVRLDPRVATSAAAIGALQVRRMDGQgNAMLSQVAHVHEVDGPPRISRDRVRRRMV 813
Cdd:COG0841 727 TLRaALGGRYVND-FNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGE-MVPLSSVATIEEGTGPSSINRYNGQRSVT 804
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 814 VQANV-RGRDLASFVAEAQARVARdVKLPAGYNMQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVAFGAVRPALLVFV 892
Cdd:COG0841 805 VSANLaPGVSLGEALAAIEELAAE-LKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLAAQFESFIQPLIILL 883
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 893 NLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVSEIAALRARGMAVAQAAFAAAESRFRPVMATALVASL 972
Cdd:COG0841 884 TVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEAARLRLRPILMTSLATIL 963
|
970 980 990
....*....|....*....|....*....|
gi 1846948815 973 GFFPMAFSESAGAEVERPLASVVIGGLVTS 1002
Cdd:COG0841 964 GLLPLALGTGAGAEFRQPLGIAVIGGLLFS 993
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
34-1007 |
9.08e-86 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 298.47 E-value: 9.08e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 34 LPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGGVSVVYVQFADDTDINLDRTRVNER 113
Cdd:NF033617 29 LPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQFRLGTDLDVALSEVQAA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 114 MQQARSNISV----PGITVSMGPLATGmgeIMQFQIRGAGRSLMELNRIMNWTVVPQMRLVPGVVDVNVNGGAEETYEVT 189
Cdd:NF033617 109 INAAQSLLPSeapdPPVYRKANSADTP---IMYIGLTSEEMPRGQLTDYAERVLAPKLSQINGVGSVDVSGGQRPAMRVW 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 190 LDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLADFGNIAVRTNPDGSAVRLRDLGRITRGAR 269
Cdd:NF033617 186 LDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYADNGAPVRLGDVATVELGAE 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 270 TRLGAVTRDGQGEIVIGVVMmESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQTIATVRDNLVMGAVLVV 349
Cdd:NF033617 266 NVRNRAWANGVPAVVLGINR-QPGANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFIRASIDEVESTLLEAVALVI 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 350 GVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGA--IDFGMIVDGSLVVIEHVlSRREEEPDAEFIPLV 427
Cdd:NF033617 345 LVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMAlvLAIGLVVDDAIVVVENI-HRHIEEGESPLEAAL 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 428 ISSvqqvmRPVGFAI----LVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPVLAALAL------GGVR 497
Cdd:NF033617 424 KGA-----REIGFTViamtLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLTPMMCSRLLkanekpGRFA 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 498 PAGDtRLIAFLRRPYTHMVTWGETHPRILFGGTLVVLALSAGLAMRLGGEFIPQLDEGALAVTTTRLPSASLDTVLASVT 577
Cdd:NF033617 499 RAVD-RFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMR 577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 578 KQEQILRSFPEVRAVVSNTGTSAIPTDPMGvnetdsFIFLNPPSTWKTARTQAGLVAAMDDTLRRELPDALYSWSqpvqm 657
Cdd:NF033617 578 DVEKILSSDPEVQSLTSFNGVGGNPGDNTG------FGIINLKPWDERDVSAQEIIDRLRPKLAKVPGMDLFLFP----- 646
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 658 rMDDLLSGV---RTQIAVSIFGDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGTVPLIVVDIDRTQAASRNVAVQDILD 734
Cdd:NF033617 647 -LQDLPGGAgssLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGS 725
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 735 TVE-AIGGHIGARpvivdnaiIGTQVR-------LDPRVATSAAAIGALQVRRMDGQGNAmLSQVAHVHEVDGPPRISRD 806
Cdd:NF033617 726 TLEvAFGQRQVNT--------IYTDGNqykvvleVDRRYRLNPEALNQIYVRSNDGKLVP-LSTLAKIEERAAPLSLNHF 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 807 RVRRRMVVQANVRGRDLASFVAEAQARVARDvKLPAGYNMQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVAFGAVRP 886
Cdd:NF033617 797 NQFNSATLSFNLAPGVSLGEAIEALDQAAKE-LLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVD 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 887 ALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVS-EIAALRARGMAVAQAAFAAAESRFRPVMA 965
Cdd:NF033617 876 PLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEfANELQRHQGLSRREAIYQAAALRLRPILM 955
|
970 980 990 1000
....*....|....*....|....*....|....*....|..
gi 1846948815 966 TALVASLGFFPMAFSESAGAEVERPLASVVIGGLVTSTLLTL 1007
Cdd:NF033617 956 TTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTL 997
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
28-998 |
7.58e-55 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 207.66 E-value: 7.58e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 28 IMTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRG-GVSVVYVQFADDTDINLD 106
Cdd:TIGR00915 24 TLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSDSdGSMTITLTFEQGTDPDIA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 107 RTRVNERMQQAR----SNISVPGITVSMGPLATGMgeIMQFQIRGAGRSLMELNRIMNWTVVPQMRLVPGVVDVNVNGgA 182
Cdd:TIGR00915 104 QVQVQNKLQLATpllpQEVQRQGVRVEKASSNFLM--VIGLVSDDGSMTKEDLSDYAASNMVDPLSRLEGVGDVQLFG-S 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 183 EETYEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWI------THHAEQQSVVGRGLVGSLADFGNIAVRTNPDGSAV 256
Cdd:TIGR00915 181 QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLgglpavPGQQLNATIIAQTRLQTPEQFENILLKVNTDGSQV 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 257 RLRDLGRITRGAR-----TRLGAVTRDGQGeivigvVMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTG 331
Cdd:TIGR00915 261 RLKDVARVELGGEnysisARFNGKPASGLA------IKLATGANALDTAKAVKAELAVLEPFFPQGMKYVYPYDTTPFVE 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 332 QTIATVRDNLVMGAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGA--IDFGMIVDGSLVVIE 409
Cdd:TIGR00915 335 ASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAmvLAIGLLVDDAIVVVE 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 410 HV--LSRREEEPDAEFIPLVISSVQQVMrpVGFAiLVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPV 487
Cdd:TIGR00915 415 NVerVMAEEGLPPKEATRKSMGQIQGAL--VGIA-MVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPA 491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 488 LAALAL----GGVRPAGDTRLIAFLRRPYTHMVTWGETHPRILFGGT---LVVLALSAG----LAMRLGGEFIPQLDEGA 556
Cdd:TIGR00915 492 LCATMLkpieKGEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRgryLLVYVLLVGgmvfLFVRLPTSFLPDEDQGV 571
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 557 LaVTTTRLPSAS----LDTVLASVTKqEQILRSFPEVRAVVSNTGTSAIPTdpmGVNETDSFIFLNPpstWKTARTQAGL 632
Cdd:TIGR00915 572 F-MTIVQLPAGAtaerTQAVLAQVTK-YLLAKEKANVESVFTVNGFSFAGR---GQNMGMAFIRLKD---WEERTGKENS 643
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 633 VAAMDDTLRREL---PDALYSWSQPVQMRMDDLLSGVRTQIAVSIfGDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGT 709
Cdd:TIGR00915 644 VFAIAGRATGHFmqiKDAMVIAFVPPAILELGNATGFDFFLQDRA-GLGHEALLQARNQLLGLAAQNPALTRVRPNGLED 722
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 710 VPLIVVDIDRTQAASRNVAVQDILDTVEAIGGHIGARPVIVDNAIIGTQVRLDPRVATSAAAIGALQVRRMDGQGNAMlS 789
Cdd:TIGR00915 723 EPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVPF-S 801
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 790 QVAHVHEVDGPPRISRDRVRRRMVVQANvrgrdlASF---VAEAQARVARDV-KLPAGYNMQWDGQfrNLQSATRRLEIV 865
Cdd:TIGR00915 802 AFATVRWEYGSPQLERYNGLPSMEILGS------AAPgvsTGQAMAAMEAIAqKLPPGFGFSWTGM--SYEERLSGSQAP 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 866 LPVALGLIFALLVVA--FGAVRPALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVSEIAALRA 943
Cdd:TIGR00915 874 ALYALSLLVVFLCLAalYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMA 953
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*
gi 1846948815 944 RGMAVAQAAFAAAESRFRPVMATALVASLGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:TIGR00915 954 QGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGG 1008
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
28-998 |
3.19e-53 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 202.39 E-value: 3.19e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 28 IMTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGGVSVVYVQFADDTDINLDR 107
Cdd:PRK09577 24 IFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAGQASLSLTFKQGVNADLAA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 108 TRVNERMQQARSNISVP----GITVSMGplATGMGEIMQFQIRGAGRSLMELNRIMNWTVVPQMRLVPGVVDVNVnGGAE 183
Cdd:PRK09577 104 VEVQNRLKTVEARLPEPvrrdGIQVEKA--ADNIQLIVSLTSDDGRLTGVELGEYASANVLQALRRVEGVGKVQF-WGAE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 184 ETYEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQS------VVGRGLVGSLADFGNIAVRTNPDGSAVR 257
Cdd:PRK09577 181 YAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSapiaatVFADAPLKTPEDFGAIALRARADGSALY 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 258 LRDLGRITRGAR-----TRLGAVTRDGQGeivigvVMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQ 332
Cdd:PRK09577 261 LRDVARIEFGGNdynypSYVNGKTATGMG------IKLAPGSNAVATEKRVRATMDELSRYFPPGVKYQIPYETSSFVRV 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 333 TIATVRDNLVMGAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLgaidFGMI------VDGSLV 406
Cdd:PRK09577 335 SMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTM----FGMVlaigilVDDAIV 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 407 VIEHVLSRREEEPDAEFIPLVissvqQVMRPVGFAIL----VIIMVYLPILTLQGIEGHMFRPMAqtviMALLASLAY-C 481
Cdd:PRK09577 411 VVENVERLMVEEGLSPYDATV-----KAMKQISGAIVgitvVLTSVFVPMAFFGGAVGNIYRQFA----LSLAVSIGFsA 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 482 FICVPVLAALALGGVRPAGD------------------------TRLIAFLRRPYTHMVTWGethprilfggtlVVLALS 537
Cdd:PRK09577 482 FLALSLTPALCATLLKPVDGdhhekrgffgwfnrfvarstqryaTRVGAILKRPLRWLVVYG------------ALTAAA 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 538 AGLAMRLGGEFIPQLDEGALAVTTTRLPSASLDTVLASVTKQEQILRSFPEVRAVVSNTGTSAIPTdpmGVNETDSFIFL 617
Cdd:PRK09577 550 ALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGE---GPNGGMIFVTL 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 618 NPPSTWKTARTQAGLVAAMDDTLRRELPD-ALYSWSQPVqmrMDDLLSG----VRTQIAVSIfgdDLAMLAELGDRVVAA 692
Cdd:PRK09577 627 KDWKERKAARDHVQAIVARINERFAGTPNtTVFAMNSPA---LPDLGSTsgfdFRLQDRGGL---GYAAFVAAREQLLAE 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 693 MSGVKGAADVAAAGDGTVPLIVVDIDRTQAASRNVAVQDILDTVEAIGG--HIGarpvivdNAIIGTQVR-----LDPRV 765
Cdd:PRK09577 701 GAKDPALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGsdYIG-------DFMHGSQVRrvivqADGRH 773
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 766 ATSAAAIGALQVRRMDGQGNAmLSQVAHVHEVDGPPRISRDRVRRRMVVQANVRGRDLASFVAEAQARVARdvKLPAGYN 845
Cdd:PRK09577 774 RLDPDDVKKLRVRNAQGEMVP-LAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAA--TLPAGIG 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 846 MQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVAFGAVRPALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFG 925
Cdd:PRK09577 851 YAWSGQSFEERLSGAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIG 930
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1846948815 926 VAILNGVVLVSEIAALRARGMAVAQAAFAAAESRFRPVMATALVASLGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:PRK09577 931 LSAKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGG 1003
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
34-998 |
3.22e-43 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 171.06 E-value: 3.22e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 34 LPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGGVSVVYVQFADDTDINLDRTRVNER 113
Cdd:PRK10614 32 LPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILQFDFDRDINGAARDVQAA 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 114 MQQARSnisvpgitvsmgPLATGM-------------GEIMQFQIRGAGRSLMELNRIMNWTVVPQMRLVPGVVDVNVNG 180
Cdd:PRK10614 112 INAAQS------------LLPSGMpsrptyrkanpsdAPIMILTLTSDTYSQGQLYDFASTQLAQTISQIDGVGDVDVGG 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 181 GAEETYEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLADFGNIAVRTNpDGSAVRLRD 260
Cdd:PRK10614 180 SSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLIIHYN-NGAAVRLGD 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 261 LGRITRGARTRLGAVTRDGQGEIVIgVVMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQTIATVRDN 340
Cdd:PRK10614 259 VATVTDSVQDVRNAGMTNAKPAILL-MIRKLPEANIIQTVDRIRAKLPELRETIPAAIDLQIAQDRSPTIRASLEEVEQT 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 341 LVMGAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGA--IDFGMIVDGSLVVIEHVlSRREEe 418
Cdd:PRK10614 338 LAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMAltIATGFVVDDAIVVLENI-SRHLE- 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 419 pdAEFIPLViSSVQQVmRPVGFAILVI----IMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPVLAALALG 494
Cdd:PRK10614 416 --AGMKPLQ-AALQGV-REVGFTVLSMslslVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLTLTPMMCAWLLK 491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 495 GVRPAGDTRLIAF------LRRPYTHMVTWGETHPRILFGGTLVVLALSAGLAMRLGGEFIPQLDEGALAVTTTRLPSAS 568
Cdd:PRK10614 492 SSKPREQKRLRGFgrmlvaLQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTFFPEQDTGRLMGFIQADQSIS 571
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 569 LDTVLASVTKQEQILRSFPEVRAVVSNTGTSAIPTDPMgvnetdsFIFLNPPSTWKTARTQagLVAAMDDTLRRELPDAL 648
Cdd:PRK10614 572 FQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMM-------FITLKPLSERSETAQQ--VIDRLRVKLAKEPGANL 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 649 ysWSQPVQmrmdDLLSGVRTQIA---VSIFGDDLAMLAELGDRVVAAMSGVKGaadvaaagdgtvpLIVVDIDRTQAASR 725
Cdd:PRK10614 643 --FLMAVQ----DIRVGGRQSNAsyqYTLLSDDLAALREWEPKIRKALAALPE-------------LADVNSDQQDKGAE 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 726 NVAVQDiLDTVEAIGGHIGARPVIVDNAIIGTQV--------------RLDPRVATSAAAIGALQVrrMDGQGNAM-LSQ 790
Cdd:PRK10614 704 MALTYD-RDTMARLGIDVQAANSLLNNAFGQRQIstiyqplnqykvvmEVDPRYTQDISALEKMFV--INNEGKAIpLSY 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 791 VAHVHEVDGPPRISRDRVRRRMVVQANV-RGRDLaSFVAEAQARVARDVKLPAGYNMQWDGQFRNLQSATRRLEIVLPVA 869
Cdd:PRK10614 781 FAKWQPANAPLSVNHQGLSAASTISFNLpTGKSL-SDASAAIERAMTQLGVPSTVRGSFAGTAQVFQETMNSQLILILAA 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 870 LGLIFALLVVAFGAVRPALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVS-EIAALRARGMAV 948
Cdd:PRK10614 860 IATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDfALEAQRNGNLTA 939
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|
gi 1846948815 949 AQAAFAAAESRFRPVMATALVASLGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:PRK10614 940 QEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGG 989
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
34-985 |
2.94e-39 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 158.46 E-value: 2.94e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 34 LPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGGVSV--VYVQFADDTDINLDR--TR 109
Cdd:PRK09579 32 LQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQNFSIisIYARIGADSDRLFTEllAK 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 110 VNERMQQARSNISVPgitvSMGPLATGMGEIMQFQIRGAGRSLMELNRIMNWTVVPQMRLVPGVVDVNVNGGAEETYEVT 189
Cdd:PRK09579 112 ANEVKNQLPQDAEDP----VLSKEAADASALMYISFYSEEMSNPQITDYLSRVIQPKLATLPGMAEAEILGNQVFAMRLW 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 190 LDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLADFGNIAVRTNPDgSAVRLRDLGRITRGAR 269
Cdd:PRK09579 188 LDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEAFAAIPVKTSGD-SRVLLGDVARVEMGAE 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 270 TRLGAVTRDGQGEIVIGVVMMESgASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQTIATVRDNLVMGAVLVV 349
Cdd:PRK09579 267 NYDSISSFDGIPSVYIGIKATPS-ANPLDVIKEVRAIMPELESQLPPNLKVSIAYDATLFIQASIDEVVKTLGEAVLIVI 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 350 GVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGA--IDFGMIVDGSLVVIEHVlSRREEEPDAEFiPLV 427
Cdd:PRK09579 346 VVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAmvLAIGLVVDDAIVVVENI-HRHIEEGKSPF-DAA 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 428 ISSVQQVMRPVGFAILVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPVLAALAL-GGVRPAGDT---- 502
Cdd:PRK09579 424 LEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALTLSPMMCALLLrHEENPSGLAhrld 503
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 503 RLIAFLRRPYTHMVTWG-ETHPRILFGGtLVVLALSAGLAMRLGGEFIPQLDEGALAVTTTRLPSASLDTVLASVTKQEQ 581
Cdd:PRK09579 504 RLFERLKQRYQRALHGTlNTRPVVLVFA-VIVLALIPVLLKFTQSELAPEEDQGIIFMMSSSPQPANLDYLNAYTDEFTP 582
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 582 ILRSFPEVRAVVSNTGTSAIPTDPMGvnetdsfiFLNPPstW-KTARTQAGLVAAMDDTLRRELPDALYSWSQPvqmRMD 660
Cdd:PRK09579 583 IFKSFPEYYSSFQINGFNGVQSGIGG--------FLLKP--WnERERTQMELLPLVQAKLEEIPGLQIFGFNLP---SLP 649
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 661 DLLSGVRTQIAVSIFGDDLAMLaELGDRVVAAMSGVKGAADVAAAGDGTVPLIVVDIDRTQAASRNVAVQDILDTVEAIG 740
Cdd:PRK09579 650 GTGEGLPFQFVINTANDYESLL-QVAQRVKQRAQESGKFAFLDIDLAFDKPEVVVDIDRAKAAQMGVSMQDLGGTLATLL 728
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 741 GHIGARPVIVDNAIIGTQVRLDPRVATSAAAIGALQVRRMDGQGNAmLSQVAHVHEVDGPprisRDRVRRRMVVQANVRG 820
Cdd:PRK09579 729 GEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLP-LSTLITLSDRARP----RQLNQFQQLNSAIISG 803
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 821 RDLASF--VAEAQARVARDvKLPAGYNMQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVAFGAVRPALLVFVNLPVAA 898
Cdd:PRK09579 804 FPIVSMgeAIETVQQIARE-EAPEGFAFDYAGASRQYVQEGSALWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSI 882
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 899 TGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVSEIAALR-ARGMAVAQAAFAAAESRFRPVMATALVASLGFFPM 977
Cdd:PRK09579 883 CGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRhEQGLSRREAIEEAAAIRLRPVLMTTAAMVFGMVPL 962
|
....*...
gi 1846948815 978 AFSESAGA 985
Cdd:PRK09579 963 ILATGAGA 970
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
29-998 |
1.32e-37 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 153.06 E-value: 1.32e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 29 MTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRG-GVSVVYVQFADDTDINLDR 107
Cdd:PRK10555 25 LAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGtGQASVTLSFKAGTDPDEAV 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 108 TRVNERMQQAR----SNISVPGITVSmgplATGMGEIMQFQIRGAGRSlMELNRIMNWTVV----PQMRlVPGVVDVNVN 179
Cdd:PRK10555 105 QQVQNQLQSAMrklpQAVQNQGVTVR----KTGDTNILTIAFVSTDGS-MDKQDIADYVASniqdPLSR-VNGVGDIDAY 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 180 gGAEETYEVTLDPARLIGSNLSVGEVYRAVDAGNA--ASG--GGW--ITHHAEQQSVVGRGLVGSLADFGNIAVRTNPDG 253
Cdd:PRK10555 179 -GSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAqiAVGqlGGTpsVDKQALNATINAQSLLQTPEQFRDITLRVNQDG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 254 SAVRLRDLGRITRGARtRLGAVTR-DGQGEIVIGvVMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQ 332
Cdd:PRK10555 258 SEVTLGDVATVELGAE-KYDYLSRfNGKPASGLG-VKLASGANEMATAKLVLNRLDELAQYFPHGLEYKVAYETTSFVKA 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 333 TIATVRDNLVMGAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGAI--DFGMIVDGSLVVIEH 410
Cdd:PRK10555 336 SIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMvlAIGLLVDDAIVVVEN 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 411 V--------LSRREEEPDAefiplvISSVQQVMrpVGFAiLVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCF 482
Cdd:PRK10555 416 VerimseegLTPREATRKS------MGQIQGAL--VGIA-MVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVLVAM 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 483 ICVPVLAALALGGVRPA---GDTRLIAFLRRPYTHMVTWGETH-PRILFGG---TLVVLALSAGLA---MRLGGEFIPQL 552
Cdd:PRK10555 487 ILTPALCATLLKPLKKGehhGQKGFFGWFNRMFNRNAERYEKGvAKILHRSlrwILIYVLLLGGMVflfLRLPTSFLPLE 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 553 DEGaLAVTTTRLPSAS-LDTVLASVTKQEQILRSfPEVRAVVSNTGTSAIPTDPMGVNETDSFIFLNPpstWKTARTQAG 631
Cdd:PRK10555 567 DRG-MFTTSVQLPSGStQQQTLKVVEKVEKYYFT-HEKDNVMSVFATVGSGPGGNGQNVARMFIRLKD---WDERDSKTG 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 632 LVAAMDDTLR---RELPDALYSWSQPVQmrmddlLSGVRTQIAVSI-------FGDDLAMLAElgDRVVAAMSGVKGAAD 701
Cdd:PRK10555 642 TSFAIIERATkafNKIKEARVIASSPPA------ISGLGSSAGFDMelqdhagAGHDALMAAR--NQLLALAAKNPELTR 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 702 VAAAGDGTVPLIVVDIDRTQAASRNVAVQDILDTVEAIGGhigarPVIVDNAIIGTQVRldpRVATSAAA--------IG 773
Cdd:PRK10555 714 VRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWG-----SSYVNDFMDRGRVK---KVYVQAAApyrmlpddIN 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 774 ALQVRRMDGqGNAMLSQVAHVHEVDGPPRIsrdrvrrrmvvqANVRGRDLASFVAEAQARV----ARDV------KLPAG 843
Cdd:PRK10555 786 LWYVRNKDG-GMVPFSAFATSRWETGSPRL------------ERYNGYSAVEIVGEAAPGVstgtAMDImeslvkQLPNG 852
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 844 YNMQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVAFGAVRPALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIAL 923
Cdd:PRK10555 853 FGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTV 932
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1846948815 924 FGVAILNGVVLVSEIAALRARGMAVAQAAFAAAESRFRPVMATALVASLGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:PRK10555 933 IGLSAKNAILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGG 1007
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
29-998 |
2.38e-37 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 152.37 E-value: 2.38e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 29 MTVLGLPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVS-RGGVSVVYVQFADDTDINLDR 107
Cdd:PRK15127 25 LAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdSTGTVQITLTFESGTDADIAQ 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 108 TRVNERMQQAR----SNISVPGITVSMGPLATGMgeIMQFqIRGAGRslMELNRIMNWT---VVPQMRLVPGVVDVNVNG 180
Cdd:PRK15127 105 VQVQNKLQLAMpllpQEVQQQGVSVEKSSSSFLM--VVGV-INTDGT--MTQEDISDYVaanMKDPISRTSGVGDVQLFG 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 181 gAEETYEVTLDPARLIGSNLSVGEVYRAVDAGNA--ASG--GGWITHHAEQ--QSVVGRGLVGSLADFGNIAVRTNPDGS 254
Cdd:PRK15127 180 -SQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAqvAAGqlGGTPPVKGQQlnASIIAQTRLTSTEEFGKILLKVNQDGS 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 255 AVRLRDLGRITRGARTRLGAVTRDGQGEIVIGVvMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQTI 334
Cdd:PRK15127 259 RVRLRDVAKIELGGENYDIIAEFNGQPASGLGI-KLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISI 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 335 ATVRDNLVMGAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSL--GAIDFGMIVDGSLVVIEHVL 412
Cdd:PRK15127 338 HEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMfgMVLAIGLLVDDAIVVVENVE 417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 413 SRREEE--PDAEFIPLVISSVQQVMrpVGFAiLVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPVLAA 490
Cdd:PRK15127 418 RVMAEEglPPKEATRKSMGQIQGAL--VGIA-MVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCA 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 491 LALGGVRP----AGDTRLIAFLRRPY---THMVTWGETH-----PRILFGGTLVVLALsAGLAMRLGGEFIPQLDEGALa 558
Cdd:PRK15127 495 TMLKPIAKgdhgEGKKGFFGWFNRMFeksTHHYTDSVGNilrstGRYLVLYLIIVVGM-AYLFVRLPSSFLPDEDQGVF- 572
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 559 VTTTRLPSASLDTVLASVTKQEQILRSFPEVRAVVSNTGTSAIPTDPMGVNETDSFIFLNPPSTWKTARTQAGLVAAMDD 638
Cdd:PRK15127 573 LTMVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRAT 652
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 639 TLRRELPDAL-YSWSQPVQMRM-----------------DDLLSGVRTQIavsifgddLAMLAELGDRVVaamsGVKgaa 700
Cdd:PRK15127 653 RAFSQIKDAMvFAFNLPAIVELgtatgfdfelidqaglgHEKLTQARNQL--------LGEAAKHPDMLV----GVR--- 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 701 dvaAAGDGTVPLIVVDIDRTQAASRNVAVQDILDTVEAIGGHIGARPVIVDNAIIGTQVRLDPRVATSAAAIGALQVRRM 780
Cdd:PRK15127 718 ---PNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAA 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 781 DGQgNAMLSQVAHVHEVDGPPRISRDRVRRRMVVQAN-VRGRDLASFVAEAQARVArdvKLPAGYNMQWDGQFRNLQSAT 859
Cdd:PRK15127 795 DGQ-MVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQaAPGKSTGEAMELMEELAS---KLPTGVGYDWTGMSYQERLSG 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 860 RRLEIVLPVALGLIFALLVVAFGAVRPALLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVsEIA 939
Cdd:PRK15127 871 NQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIV-EFA 949
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1846948815 940 A--LRARGMAVAQAAFAAAESRFRPVMATALVASLGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:PRK15127 950 KdlMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGG 1010
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
34-998 |
2.27e-32 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 136.40 E-value: 2.27e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 34 LPVEAVPDISPRQVLVSVVAPGLATEEVEKLITFPVETSMTGIPGMTDLRSVSRGGVSVVYVQFadDTDINLDrtrVNER 113
Cdd:PRK10503 41 LPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITLQF--QLTLPLD---VAEQ 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 114 MQQARSNISV---------PGITVSMGPLATgmgEIMQFQIRGAGRSLMELNRIMNWTVVPQMRLVPGVVDVNVNGGAEE 184
Cdd:PRK10503 116 EVQAAINAATnllpsdlpnPPVYSKVNPADP---PIMTLAVTSTAMPMTQVEDMVETRVAQKISQVSGVGLVTLSGGQRP 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 185 TYEVTLDPARLIGSNLSVGEVYRAVDAGNAASGGGWITHHAEQQSVVGRGLVGSLADFGNIAVrTNPDGSAVRLRDLGRI 264
Cdd:PRK10503 193 AVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAEEYRQLII-AYQNGAPIRLGDVATV 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 265 TRGAR-TRLGAVTrDGQGEIVIGvVMMESGASSNATLAAINRALPGIRQALPAGVTIEPYYTRATLTGQTIATVRDNLVM 343
Cdd:PRK10503 272 EQGAEnSWLGAWA-NKQQAIVMN-VQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELML 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 344 GAVLVVGVLVVVIGRWQAALVIASVIPVALVCAMAGMRQFGISANLLSLGA--IDFGMIVDGSLVVIEHVlSRREEEPDA 421
Cdd:PRK10503 350 AIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMAltIATGFVVDDAIVVIENI-SRYIEKGEK 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 422 efiPLviSSVQQVMRPVGFAIL----VIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPVLAALALGGVR 497
Cdd:PRK10503 429 ---PL--AAALKGAGEIGFTIIsltfSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSQES 503
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 498 PAGDTRLI----AFLRR---PYTHMVTWGETHPRILFGGTLVVLALSAGLAMRLGGEFIPQLDEGALAVTTTRLPSASLD 570
Cdd:PRK10503 504 LRKQNRFSraseRMFDRviaAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFFPVQDNGIIQGTLQAPQSSSFA 583
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 571 tvlASVTKQEQIlrsfpevravvsntgTSAIPTDPmGVNETDSFIFL---NPpsTWKTARTQAGL--VAAMDDTLRRELP 645
Cdd:PRK10503 584 ---NMAQRQRQV---------------ADVILQDP-AVQSLTSFVGVdgtNP--SLNSARLQINLkpLDERDDRVQKVIA 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 646 ---------DALYSWSQPVQ-MRMDDLLSgvRTQIAVSIFGDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGTVPLIVV 715
Cdd:PRK10503 643 rlqtavakvPGVDLYLQPTQdLTIDTQVS--RTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYV 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 716 DIDRTQAASRNVAVQDILDtveAIGGHIGARPVivdnAIIGTQ-----VRLDPRVATSaAAIGALQVRRMDGQGNAM--L 788
Cdd:PRK10503 721 NVDRDSASRLGISMADVDN---ALYNAFGQRLI----STIYTQanqyrVVLEHNTENT-PGLAALDTIRLTSSDGGVvpL 792
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 789 SQVAHVHEVDGPPRISRDRVRRRMVVQANVRGRDLASFVAEAQARVARDVKLPAGYNMQWDGQFRNLQSA---TRRLEIV 865
Cdd:PRK10503 793 SSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSAlgsTVWLIVA 872
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 866 LPVALGLIFALLVVAFgaVRPaLLVFVNLPVAATGGIVALTLRGMPFSISAGIGFIALFGVAILNGVVLVS-EIAALRAR 944
Cdd:PRK10503 873 AVVAMYIVLGVLYESF--IHP-ITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDfALAAEREQ 949
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....
gi 1846948815 945 GMAVAQAAFAAAESRFRPVMATALVASLGFFPMAFSESAGAEVERPLASVVIGG 998
Cdd:PRK10503 950 GMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGG 1003
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-417 |
2.77e-11 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 67.82 E-value: 2.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 1 MAHAY---LATLIRARMLVLGGLGLLLAAGIMTVLGLPVEAVPDISPRQVLVSVVAPGLAT--------EEVEKLI-TFP 68
Cdd:COG0841 511 LTRGYgrlLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSlerteavvRQVEEILlEVP 590
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 69 -VETSMTGIPGMTDLRSVSRGgvsVVYVQFADDTDINLDRTRVNERMQQARSNIsvPGITVSM-GPLATGMGEIMQFQIR 146
Cdd:COG0841 591 eVESVFSVVGFSGGGSGSNSG---TIFVTLKPWDERDRSADEIIARLREKLAKI--PGARVFVfQPPAGGLGSGAPIEVQ 665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 147 GAGRSLMELNRIMNwTVVPQMRLVPGVVDVNVNGGA-EETYEVTLDPARLIGSNLSVGEVYRAVdagNAASGGGWIT--- 222
Cdd:COG0841 666 LQGDDLEELAAAAE-KLLAALRQIPGLVDVRSDLQLgKPELQLDIDREKAAALGVTVADVASTL---RAALGGRYVNdfn 741
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 223 HHAEQQSVVGR---GLVGSLADFGNIAVRtNPDGSAVRLRDLGRITRGarTRLGAVTR-DGQGEIVIGVVMMEsGASSNA 298
Cdd:COG0841 742 RGGREYDVRVQapeEDRNSPEDLENLYVR-TPDGEMVPLSSVATIEEG--TGPSSINRyNGQRSVTVSANLAP-GVSLGE 817
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 299 TLAAINRALPgiRQALPAGVTIEP---YYTRATLTGQT-------IATVRdnLVMGAvlvvgvlvvVIGRWQAALVIASV 368
Cdd:COG0841 818 ALAAIEELAA--ELKLPPGVSIEFtgqAEEEQESFSSLglafllaLLLVY--LVLAA---------QFESFIQPLIILLT 884
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1846948815 369 IPVALVCAMAGMRQFGISANLLSL-GAID-FGMIVDGSLVVIEHVLSRREE 417
Cdd:COG0841 885 VPLALIGALLGLLLTGTPLNIYSQiGLIMlIGIVVKNAILLVDFANQLREE 935
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
862-982 |
1.44e-07 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 55.64 E-value: 1.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 862 LEIVLPVALGLIFALLVVAFGAVRPALLVFVN--LPVAATGGIVALTlrGMPFSISAGIGFIALFGVAILNGVVLVSEIA 939
Cdd:COG1033 220 LAIFFPLALLLILLLLFLFFRSLRGVLLPLLVvlLAVIWTLGLMGLL--GIPLSPLTILVPPLLLAIGIDYGIHLLNRYR 297
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1846948815 940 ALRARGMAVAQAAFAAAESRFRPVMATALVASLGFFPMAFSES 982
Cdd:COG1033 298 EERRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDI 340
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-491 |
2.70e-07 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 54.99 E-value: 2.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 3 HAY---LATLIRARMLVLGGLGLLLAAGIMTVLGLPVEAVPDISPRQVLVSVVAPGLAT--------EEVEKLIT-FPVE 70
Cdd:pfam00873 514 RGYaklLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSldqtqrvmKQVEKILKeKPEV 593
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 71 TSMTGIPGM---TDLRSVSRGGVSVVYVQFADDTDINLDRTRVNERMQQARSNIsvPGITVSMGP------LATGMGEIM 141
Cdd:pfam00873 594 ESVFAVTGFafsGDNNGPNSGDAFISLKPWKERPGPEKSVQALIERLRKALKQI--PGANVFLFQpiqlrgLGTISGFRS 671
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 142 QFQIRGAGRSLMELNRIMNwTVVPQMRLVPGVVDVNVNGgAEETYEVTLDPARLIGSNL--SVGEVYRAVdagNAASGGG 219
Cdd:pfam00873 672 DLQVKIFGDDLDALDEARN-QILAALAQLPGLSDVRSDG-QEDQPQLQVNIDREKAARLgvSIQDINDTL---STALGGS 746
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 220 WITHHAEQQSVV------GRGLVGSLADFGNIAVRtNPDGSAVRLRDLGRITRGARTrlGAVTR-DGQGEIVIGVVMMEs 292
Cdd:pfam00873 747 YVNDFPEGGRVYdvvvqlPEDFRSSPEDIGQLYVR-NPYGKMIPLSAFAKIEWGYGP--PSINRyNGFRSIVISGNVAA- 822
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 293 GASSNATLAAINRALPGIRqaLPAGVTIEP---YYTRATLTGQT-----IATVRDNLVMGAVlvvgvlvvvIGRWQAALV 364
Cdd:pfam00873 823 GDSLGDAMEAMAQIAKQVK--LPPGYGYTWtgqFEQEQLAGNSLpiliaLALLVVFLVLAAL---------YESWSDPLS 891
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 365 IASVIPVALVCAMAGMRQFGISANLLSL-GAID-FGMIVDGSLVVIEHVLSRREEEpDAEFIPLVISSVQQVMRPVGFAI 442
Cdd:pfam00873 892 IMLTVPLALVGALLALWLRGLPNSVYAQvGLILlIGLAVKNAILMVEFANELREQE-GKSLEEAILEACRLRLRPILMTA 970
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 1846948815 443 LVIIMVYLPILTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPVLAAL 491
Cdd:pfam00873 971 LAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVL 1019
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
816-981 |
2.09e-06 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 51.78 E-value: 2.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 816 ANVRGRDLASFVAEAQARVARDVKlPAGYNMQWDGQFRNLQSATRRLE----IVLPVALGLIFALLVVAFGAVRPALL-V 890
Cdd:COG1033 558 KDLDSEEIKALVEEVRAFLAENFP-PDGVEVTLTGSAVLFAAINESVIesqiRSLLLALLLIFLLLLLAFRSLRLGLIsL 636
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 891 FVN-LPVAATGGIVALTlrGMPFSISAGIGFIALFGVAILNGVVLVSEIAALRARGMAVAQAAFAAAESRFRPVMATALV 969
Cdd:COG1033 637 IPNlLPILLTFGLMGLL--GIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLT 714
|
170
....*....|..
gi 1846948815 970 ASLGFFPMAFSE 981
Cdd:COG1033 715 LAAGFGVLLFSS 726
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
358-594 |
5.60e-05 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 47.16 E-value: 5.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 358 RWQAALVIASVIPVALVCAMAGMRQFGISANLLS--LGAIDFGMIVDGSLvvieHVLSRREEE--PDAEFIPLVISSVQQ 433
Cdd:COG1033 241 SLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTilVPPLLLAIGIDYGI----HLLNRYREErrKGLDKREALREALRK 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 434 VMRPVGFAILVIIMVYLpilTLQGIEGHMFRPMAQTVIMALLASLAYCFICVPVLAALALGGVRPAGDTRLIAFLRRPYT 513
Cdd:COG1033 317 LGPPVLLTSLTTAIGFL---SLLFSDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPPELGRLLA 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 514 HMVTWGETHPRILFGGTLVVLALSAGLAMRL--GGEFIPQLDEG-----ALAVTTTRLPSAS-----LDT---------- 571
Cdd:COG1033 394 KLARFVLRRPKVILVVALVLAVVSLYGISRLkvEYDFEDYLPEDspirqDLDFIEENFGGSDplevvVDTgepdglkdpe 473
|
250 260
....*....|....*....|...
gi 1846948815 572 VLASVTKQEQILRSFPEVRAVVS 594
Cdd:COG1033 474 VLKEIDRLQDYLESLPEVGKVLS 496
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
464-992 |
6.62e-04 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 43.71 E-value: 6.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 464 RPMAQTV-----IMALLASLAYCFICV---PVLAALALGGVRPAGDTRLIAFLRRP--------------YTHMVT--WG 519
Cdd:COG3321 771 RHLRQPVrfadaVEALLADGVRVFLEVgpgPVLTGLVRQCLAAAGDAVVLPSLRRGedelaqlltalaqlWVAGVPvdWS 850
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 520 ETHPRilFGGTLVVLALSA----GLAMRLGGEFIPQLDEGALAVTTTRLPSASLDTVLASVTKQEQILRSFPEVRAVVSN 595
Cdd:COG3321 851 ALYPG--RGRRRVPLPTYPfqreDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAA 928
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 596 TGTSAIPTDPMGVNETDSFIFLNPPSTWKTARTQAGLVAAMDDTLRRELPDALYSWSQPVQMRMDDLLSGVRTQIAVSIF 675
Cdd:COG3321 929 LLALVALAAAAAALLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAA 1008
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 676 GDDLAMLAELGDRVVAAMSGVKGAADVAAAGDGTVPLIVVDIDRTQAASRNVAVQDILDTVEAIGGHIGARPVIVDNAII 755
Cdd:COG3321 1009 ALLLAAAAAAAALLALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAA 1088
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 756 GTQVRLDPRVATSAAAIGALQVRRMDGQGNAMLSQV--AHVHEVDGPPRISRDRVRRRMVVQANVRGRDLASFVAEAQAR 833
Cdd:COG3321 1089 ALAAAALALALAALAAALLLLALLAALALAAAAAALlaLAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALL 1168
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 834 VARDVKLPAGYNMQWDGQFRNLQSATRRLEIVLPVALGLIFALLVVAFGAVRPALLVFVNLPVAATGGIVALTLRGMPFS 913
Cdd:COG3321 1169 AAAALLLALALALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAAL 1248
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1846948815 914 ISAGIGFIALFGVAILNGVVLVSEIAALRARGMAVAQAAFAAAESRFRPVMATALVASLGFFPMAFSESAGAEVERPLA 992
Cdd:COG3321 1249 AAAAAALLAALAALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLA 1327
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
856-984 |
5.75e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 40.61 E-value: 5.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1846948815 856 QSATRRLEIVLPVALGLIFALLVVAFGAVRPALLVFVNLPVAATGGIVALTL-RGMPFSISAGIGFiALFGVAILNGVVL 934
Cdd:COG4258 245 QQIKHDISTIGLISLLGILLLLLLVFRSLRPLLLGLLPVAVGALAGLAAVSLvFGSVHGITLGFGS-SLIGVAVDYSLHY 323
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1846948815 935 VSEIAALRARGMAVAQaafaaaeSRFRPVMATALVAS-LGFFPMAFSESAG 984
Cdd:COG4258 324 LTHRRAAGEWDPRAAL-------RRIWPTLLLGLLTTvLGYLALLFSPFPG 367
|
|
| |
