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Conserved domains on  [gi|1844517551|ref|XP_034493581|]
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fam-a protein [Plasmodium yoelii]

Protein Classification

PYST-A family protein( domain architecture ID 28115)

PYST-A family protein is incoded by one of a paralogous family of Plasmodium genes preferentially located in the subtelomeric regions of the chromosomes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PYST-A super family cl11754
Plasmodium yoelii subtelomeric family PYST-A; This model represents a paralogous family of ...
 47-250 1.12e-63

Plasmodium yoelii subtelomeric family PYST-A; This model represents a paralogous family of Plasmodium yoelii genes preferentially located in the subtelomeric regions of the chromosomes. Members of this family are expressed in both the Sporozoite and Gametozoite life stages. A single high-scoring gene was identified in the complete genome of P. falciparum as well as a single gene from P. chaboudi from GenBank which were included in the seed. There are no obvious homologs to these genes in any non-Plasmodium organism. These observations suggest an expansion of this family in yoelii from a common Plasmodium ancestor gene (present in a single copy in falciparum).


The actual alignment was detected with superfamily member TIGR01599:

Pssm-ID: 273712  Cd Length: 208  Bit Score: 198.78  E-value: 1.12e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1844517551  47 KYKDMACYSIYENLvAIDHANNTSELLIKLSETSTDDYSTHPTENGDKIIYSKKIGNMDIGRLHLTIPSASNYYDVIEEL 126
Cdd:TIGR01599   2 KKPHLVCTDPKEIK-RAEEIMEEAELRLKRHAINKNDYNLYSTPNPDSTVYYKKDHNTIIGKIHLTIQDPNKYDAIIKTL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1844517551 127 WDFNDTQKYNYKFIKGSLARVYSKDLIIFEKLNIDPKYVPFVKKYVLAAKVKHSNDTTVILCPSRALNYLGKIDDEPNMK 206
Cdd:TIGR01599  81 WDFNDNKKFGRKFIKGKVVRVYSPNLIMIQQRYKDASGSPNKYFYALATKVKVSEDTTIIACTSANINDHNKVDKKNFKN 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1844517551 207 EILENTQLIETEIDPEEA-----LIKLGTNISGFVIKKvENDQVDVTYI 250
Cdd:TIGR01599 161 KIIESANSFKTDIDSEEDirngeLKKMFVNLSGFIIKK-KDDNIDITYV 208
 
Name Accession Description Interval E-value
PYST-A TIGR01599
Plasmodium yoelii subtelomeric family PYST-A; This model represents a paralogous family of ...
 47-250 1.12e-63

Plasmodium yoelii subtelomeric family PYST-A; This model represents a paralogous family of Plasmodium yoelii genes preferentially located in the subtelomeric regions of the chromosomes. Members of this family are expressed in both the Sporozoite and Gametozoite life stages. A single high-scoring gene was identified in the complete genome of P. falciparum as well as a single gene from P. chaboudi from GenBank which were included in the seed. There are no obvious homologs to these genes in any non-Plasmodium organism. These observations suggest an expansion of this family in yoelii from a common Plasmodium ancestor gene (present in a single copy in falciparum).


Pssm-ID: 273712  Cd Length: 208  Bit Score: 198.78  E-value: 1.12e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1844517551  47 KYKDMACYSIYENLvAIDHANNTSELLIKLSETSTDDYSTHPTENGDKIIYSKKIGNMDIGRLHLTIPSASNYYDVIEEL 126
Cdd:TIGR01599   2 KKPHLVCTDPKEIK-RAEEIMEEAELRLKRHAINKNDYNLYSTPNPDSTVYYKKDHNTIIGKIHLTIQDPNKYDAIIKTL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1844517551 127 WDFNDTQKYNYKFIKGSLARVYSKDLIIFEKLNIDPKYVPFVKKYVLAAKVKHSNDTTVILCPSRALNYLGKIDDEPNMK 206
Cdd:TIGR01599  81 WDFNDNKKFGRKFIKGKVVRVYSPNLIMIQQRYKDASGSPNKYFYALATKVKVSEDTTIIACTSANINDHNKVDKKNFKN 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1844517551 207 EILENTQLIETEIDPEEA-----LIKLGTNISGFVIKKvENDQVDVTYI 250
Cdd:TIGR01599 161 KIIESANSFKTDIDSEEDirngeLKKMFVNLSGFIIKK-KDDNIDITYV 208
 
Name Accession Description Interval E-value
PYST-A TIGR01599
Plasmodium yoelii subtelomeric family PYST-A; This model represents a paralogous family of ...
 47-250 1.12e-63

Plasmodium yoelii subtelomeric family PYST-A; This model represents a paralogous family of Plasmodium yoelii genes preferentially located in the subtelomeric regions of the chromosomes. Members of this family are expressed in both the Sporozoite and Gametozoite life stages. A single high-scoring gene was identified in the complete genome of P. falciparum as well as a single gene from P. chaboudi from GenBank which were included in the seed. There are no obvious homologs to these genes in any non-Plasmodium organism. These observations suggest an expansion of this family in yoelii from a common Plasmodium ancestor gene (present in a single copy in falciparum).


Pssm-ID: 273712  Cd Length: 208  Bit Score: 198.78  E-value: 1.12e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1844517551  47 KYKDMACYSIYENLvAIDHANNTSELLIKLSETSTDDYSTHPTENGDKIIYSKKIGNMDIGRLHLTIPSASNYYDVIEEL 126
Cdd:TIGR01599   2 KKPHLVCTDPKEIK-RAEEIMEEAELRLKRHAINKNDYNLYSTPNPDSTVYYKKDHNTIIGKIHLTIQDPNKYDAIIKTL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1844517551 127 WDFNDTQKYNYKFIKGSLARVYSKDLIIFEKLNIDPKYVPFVKKYVLAAKVKHSNDTTVILCPSRALNYLGKIDDEPNMK 206
Cdd:TIGR01599  81 WDFNDNKKFGRKFIKGKVVRVYSPNLIMIQQRYKDASGSPNKYFYALATKVKVSEDTTIIACTSANINDHNKVDKKNFKN 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1844517551 207 EILENTQLIETEIDPEEA-----LIKLGTNISGFVIKKvENDQVDVTYI 250
Cdd:TIGR01599 161 KIIESANSFKTDIDSEEDirngeLKKMFVNLSGFIIKK-KDDNIDITYV 208
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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